Готові списки джерел за темами / Veterinary pharmaceutical

Добірка наукової літератури з теми "Veterinary pharmaceutical"

Автор: Grafiati
Опубліковано: 7 вересня 2022
Оновлено: 18 вересня 2022

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Статті в журналах з теми "Veterinary pharmaceutical"

1

Im, Jong Kwon, Sang Hun Kim, Young Seuk Kim, and Soon Ju Yu. "Spatio-Temporal Distribution and Influencing Factors of Human and Veterinary Pharmaceuticals in the Tributary Surface Waters of the Han River Watershed, South Korea." International Journal of Environmental Research and Public Health 18, no. 15 (July 28, 2021): 7969. http://dx.doi.org/10.3390/ijerph18157969.

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Human and veterinary pharmaceuticals are being increasingly used for disease treatment; hence, their distribution and factors influencing them in the aquatic environment need to be investigated. This study observed the effect of human and animal populations, usage, purchasing criteria (prescription vs. non-prescription), and land use to identify the spatio-temporal distribution of eight pharmaceuticals at twenty-four sites of the tributaries of the Han River watershed. In rural areas, the mean concentration (detection frequency) of non-prescription pharmaceuticals (NPPs) was higher (lower) compared to that of prescription pharmaceuticals (PPs); in urban areas, a reverse trend was observed. Pharmaceutical concentrations in urban and rural areas were mainly affected by wastewater treatment plants (WWTPs) and non-point sources, respectively; concentrations were higher downstream (4.9 times) than upstream of the WWTPs. The concentration distribution (according to the target) was as follows: human–veterinary > human > veterinary. Correlation between total concentration and total usage of the pharmaceuticals was high, except for NPPs. Most livestock and land use (except cropland) were significantly positively correlated with pharmaceutical concentrations. Concentrations were mainly higher (1.5 times) during cold seasons than during warm seasons. The results of this study can assist policymakers in managing pharmaceutical pollutants while prioritizing emerging pollutants.
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2

Küster, Anette, and Nicole Adler. "Pharmaceuticals in the environment: scientific evidence of risks and its regulation." Philosophical Transactions of the Royal Society B: Biological Sciences 369, no. 1656 (November 19, 2014): 20130587. http://dx.doi.org/10.1098/rstb.2013.0587.

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During the past two decades scientists, regulatory agencies and the European Commission have acknowledged pharmaceuticals to be an emerging environmental problem. In parallel, a regulatory framework for environmental risk assessment (ERA) of pharmaceutical products has been developed. Since the regulatory guidelines came into force the German Federal Agency (UBA) has been evaluating ERAs for human and veterinary pharmaceutical products before they are marketed. The results show that approximately 10% of pharmaceutical products are of note regarding their potential environmental risk. For human medicinal products, hormones, antibiotics, analgesics, antidepressants and antineoplastics indicated an environmental risk. For veterinary products, hormones, antibiotics and parasiticides were most often discussed as being environmentally relevant. These results are in good correlation with the results within the open scientific literature of prioritization approaches for pharmaceuticals in the environment. UBA results revealed that prospective approaches, such as ERA of pharmaceuticals, play an important role in minimizing problems caused by pharmaceuticals in the environment. However, the regulatory ERA framework could be improved by (i) inclusion of the environment in the risk–benefit analysis for human pharmaceuticals, (ii) improvement of risk management options, (iii) generation of data on existing pharmaceuticals, and (iv) improving the availability of ERA data. In addition, more general and integrative steps of regulation, legislation and research have been developed and are presented in this article. In order to minimize the quantity of pharmaceuticals in the environment these should aim to (i) improve the existing legislation for pharmaceuticals, (ii) prioritize pharmaceuticals in the environment and (iii) improve the availability and collection of pharmaceutical data.
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3

Ahmed, I. "Pharmaceutical challenges in veterinary product development." Advanced Drug Delivery Reviews 54, no. 6 (October 4, 2002): 871–82. http://dx.doi.org/10.1016/s0169-409x(02)00074-1.

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4

Li, Z. H., and T. Randak. "Residual pharmaceutically active compounds (PhACs) in aquatic environment – status, toxicity and kinetics: a review." Veterinární Medicína 54, No. 7 (August 18, 2009): 295–314. http://dx.doi.org/10.17221/97/2009-vetmed.

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Анотація:
Awareness of residual pharmaceutically active compounds (PhACs) in aquatic ecosystems is growing as research into these pollutants increases and analytical detection techniques improve. For most pharmaceuticals analyzed, the effects on aquatic organisms have usually been investigated by toxic assays in the laboratory. However, little is known about integral analysis of pharmacokinetics in aquatic organisms and specific relations between pharmacokinetic parameters and influence factors. Moreover, the influence of the organisms involved and numerous other external factors complicates development of standard tests for environmental evaluation. Current knowledge about residual pharmaceuticals in the aquatic environment, including status, toxic effects, and pharmacokinetics in aquatic organisms, are reviewed. Based on the above, we identify major gaps in the current knowledge and some directions for future research, such as improvement of techniques to remove residual pharmaceuticals from wastewater, and the establishment of standard pharmaceutical modes of action.
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Priya, K. Vamsi, K. Umasankar, J. Praveen Kumar, and M. Kishore Babu. "Comparative study of medicinal products registration in USA and Europe." World Journal of Pharmaceutical Sciences 10, no. 03 (2022): 263–66. http://dx.doi.org/10.54037/wjps.2022.100303.

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Анотація:
A pharmaceutical drug regulatory Affairs is mainly involved in registration process parameters of different pharmaceutical products and new drug application. Regulatory affairs professionals play vital roles in a pharmaceutical field as; it is related to healthcare products. The present article mainly focuses to provide similarities and differences in the registration of medicinal products in USA and European countries.This also provide details to protect public health in terms of safety, quality, and efficacy of products like medical devices, pharmaceuticals, veterinary medicines, pesticides, cosmetics & complementary medicines, agrochemicals, etc.
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6

Deshkar, Anuradha T., Ujwala P. Gawali, and Prashant A. Shirure. "Environmental pharmacology: an emerging science." International Journal of Basic & Clinical Pharmacology 7, no. 3 (February 22, 2018): 359. http://dx.doi.org/10.18203/2319-2003.ijbcp20180645.

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Анотація:
With continuous rapid expansion of the human population there is escalating demand for resources, including human and veterinary pharmaceuticals. This has lead to rapid development of global pharmaceutical industry and with that increase in issues caused by pharmaceutical products. In recent years a great concern has been expressed over the occurrence and persistence of pharmaceutical products in the environment and their potential impact on environment. Owing to this the new branch of science called environmental pharmacology has sprouted. Environmental pharmacology deals with dispersion and impact of pharmaceutical products on environment. Solutions need to be suggested to save this only liveable planet from ill effects of these pharmaceutical products. This has given birth to the science of Ecopharmacovigilance (EPV).
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MKALA, REUBEN SUNZU. "Antibiotic prescription practice at veterinary pharmaceutical shops and its potential impact on the development of antimicrobial resistance in Moshi, Northern Tanzania." Journal of Drug Delivery and Therapeutics 12, no. 1-S (February 15, 2022): 100–104. http://dx.doi.org/10.22270/jddt.v12i1-s.5285.

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Aim: We aimed to investigate antibiotic prescription practice in veterinary shops and its potential impact on the development of antimicrobial resistance. Methods: A correlation cross-sectional study was carried out in Moshi, Tanzania. A convenient sampling method was used to enroll 80 study participants and 80 Veterinary pharmaceutical shops selling antibiotics for cattle. The study questionnaire was administered to both pharmaceutical sellers and cattle keepers Results: A total of 80 veterinary pharmaceutical shops visited to deliver information about antibiotics sold with or without prescription from veterinary professionals and eighty (80) human participants. Most of the study participant 66/80 (82.5%) responded to started treatment before laboratory diagnosis and diagnosis was mainly based on symptoms and signs 58/80 (72.5%); owners description 17/80 (21.3%) and less frequently on none specific reason 15/80 (6.5%) (Χ2=77.89, P= 0.000, OR=0.875, 95% CI= 0.803-0.947). Tetracycline 30 (100%), Trimethoprim/sulfamethoxazole 10 (100%), and amoxicillin/clavulanic acid 7 (100%) were highly sold unprescribed drugs and no quantity of these drugs was prescribed before selling at Veterinary pharmaceutical shops. Conclusion: The regulation of Veterinary antibiotic prescription at veterinary pharmaceutical shops has to be a point of discussion and paid greater attention to ensure a sustainable control and reduction of transmission and spread of drug-resistant bacteria in humans and cattle. Keywords: antibiotic prescription practice, antimicrobial resistance, Veterinary pharmaceutical shops
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Brander, G. "The pharmaceutical industry and The Veterinary Record." Veterinary Record 123, no. 1 (July 2, 1988): 20–23. http://dx.doi.org/10.1136/vr.123.1.20.

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Capon, Hannah. "Understanding the pharmaceutical approach to pain management in canine osteoarthritis." Companion Animal 26, no. 6 (June 2, 2021): 73–80. http://dx.doi.org/10.12968/coan.2021.0039.

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Анотація:
Canine osteoarthritis was recently reclassified as a welfare concern by the Veterinary Companion Animal Surveillance System (VetCompass), an initiative run by the Royal College of Veterinary Surgeons, focused on improving companion animal health. This condition is a common cause for consultation in first opinion practice, with an estimated 35% of the canine population being affected. Chronic pain is complex and a multimodal approach is best for management, which includes pharmaceuticals employed in a methodical manner. This article provides an overview of the types of pain associated with canine osteoarthritis, as well as how to recognise them. Making reference to hypothetical cases, the appropriate pharmaceutical management is described. Further management strategies, as part of a multimodal approach, are summarised to ensure best practice.
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Stando, Klaudia, Ewa Korzeniewska, Ewa Felis, Monika Harnisz, and Sylwia Bajkacz. "Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues." Molecules 27, no. 14 (July 8, 2022): 4378. http://dx.doi.org/10.3390/molecules27144378.

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Анотація:
Manure is a major source of soil and plant contamination with veterinary drugs residues. The aim of this study was to evaluate the uptake of 14 veterinary pharmaceuticals by parsley from soil fertilized with manure. Pharmaceutical content was determined in roots and leaves. Liquid chromatography coupled with tandem mass spectrometry was used for targeted analysis. Screening analysis was performed to identify transformation products in the parsley tissues. A solid-liquid extraction procedure was developed combined with solid-phase extraction, providing recoveries of 61.9–97.1% for leaves and 51.7–95.6% for roots. Four analytes were detected in parsley: enrofloxacin, tylosin, sulfamethoxazole, and doxycycline. Enrofloxacin was detected at the highest concentrations (13.4–26.3 ng g−1). Doxycycline accumulated mainly in the roots, tylosin in the leaves, and sulfamethoxazole was found in both tissues. 14 transformation products were identified and their distribution were determined. This study provides important data on the uptake and transformation of pharmaceuticals in plant tissues.
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Більше джерел

Дисертації з теми "Veterinary pharmaceutical"

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Oppel, Katrin. "Taste masking of an active pharmaceutical ingredient for veterinary application /." [S.l.] : [s.n.], 2008. http://edoc.unibas.ch/diss/DissB_8737.

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Scandurra, Salvatore <1973&gt. "Veterinary drugs in drinking water used for pharmaceutical treatments in breeding farms." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5673/.

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Анотація:
Water is susceptible to be used for numerous purposes, including edible, both for humans and animals. In the food animal production, drinking water is frequently used as a way to carry out the most common pharmacological treatments. In these cases, there are many variables which could degrade drugs dissolved in this mean, even when properly arranged pharmaceutical formulations are used. In fact, although a product obtains a Marketing Authorization through appropriate laboratory studies both drug stability and solubility, on the other hand the solubility of the same drug in natural water used as a drinking water is not documented. In the present study has been evaluated the dissolution kinetics (at 0 hours and 24 hours) of products, having oxytetracycline and tylosin as active ingredient, used in drinking water samples in order to see how the different physical and chemical factors that characterize the drinking water may affect therapeutic efficacy. In fact, multiple factors, also of little relevance if individually considered, are able to adversely affect the pharmacological treatment carried out in drinking water.
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3

Kirk, Loren, and Stacy D. Brown. "Beyond-Use Date Determination for Buprenorphine Buccal Veterinary Solution Using Validated High-Performance Liquid Chromatographic Method." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/5283.

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4

Steve, Donna L. "Analytical techniques used in the development of quantitative and qualitative assays for pharmaceutical and biological products in animal health." Kansas State University, 2017. http://hdl.handle.net/2097/35491.

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Анотація:
Master of Science in Biomedical Sciences
Department of Diagnostic Medicine/Pathobiology
Alison P. Adams
The animal health industry is a growing industry. Owners of pets and other animals want to ensure their animals are healthy. To do this, the animal health industry markets a variety of products from pharmaceutical products, such as antibiotics, to biological products, such as vaccines. These products are developed and marketed after the company provides regulators the necessary information as guided by a set of regulations. Pharmaceutical products follow Title 21 of the Code of Federal Regulations, while biological products follow Title 9 of the Code of Federal Regulations. During the product development process as well as after marketing, regardless of the regulations to follow, each product must go through testing for efficacy, safety, potency, and stability. The regulatory guidelines provide direction to companies on expectations of the testing requirements for each type of product. Different analytical techniques are used to provide the necessary data in support of product development. Discussed in this report, two analytical techniques are well known in the industry, and one is quickly becoming a technique of great value. Mass spectrometry, coupled with liquid chromatography, is an industry standard for testing product potency and purity as well as pharmacokinetics. The enzyme-linked immunosorbent assay (ELISA) is also used to measure potency of products as well as product stability. The newest technique is flow cytometry that characterizes cells within a suspension, most often with the use of cellular biomarkers as targets. By understanding the application of each technique as well as how it relates to regulatory requirements, the industry can provide assurances to regulators that their products are safe and efficacious for the treatment and/or prevention of animal diseases. This report outlines the history, theory, and use of three different analytical techniques currently used for pharmaceutical and biological products in animal health.
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Kirk, Loren, and Stacy D. Brown. "Validated High-Performance Liquid Chromatographic Method for Buprenorphine Quantification in Oral Veterinary Solution for Application Toward a Beyond-Use Date Determination." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/5286.

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Barbosa, Carolina Cive. "Perfil de inovação farmacêutica veterinária no Brasil." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/74/74134/tde-27112017-110751/.

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Анотація:
A pesquisa objetivou avaliar o estado da arte da inovação no setor de saúde animal, tanto no sentido de saber como e o que está sendo produzido, quanto à verificação de possíveis interações com as universidades. Ainda, a ausência de trabalhos publicados avaliando os tipos de patentes depositadas, bem como os grupos de pesquisa que atuam, direta ou indiretamente, nesta área fortaleceu a necessidade de iniciar uma pesquisa nesse sentido. Assim, por meio do levantamento e classificação de patentes depositadas, no Brasil, por indústrias de saúde animal e universidades públicas bem com estudo dos grupos de pesquisa do CNPq, buscou-se verificar o perfil de produção científico/tecnológico entre os dois atores principais (públicos e privados). Além disso, pontuou-se o que existe de demanda e oportunidade para inovação em saúde animal e fez-se uma primeira análise do nível de interação entre os grupos de pesquisa, que poderiam representar oportunidades de inovação, e empresas. Os resultados mostraram que o perfil de produção científica e tecnologia dos dois atores envolvidos, indústria e universidades, é distinto. Observa-se que as empresas de saúde animal apresentam maior número de depósitos de patente nas áreas de produtos biológicos e antiparasitários, enquanto as universidades apresentam pesquisas mais diluídas em temas de interesse para o setor de saúde animal, o que foi verificado tanto nas patentes depositadas quando na avaliação dos grupos de pesquisa. Ainda, verificou-se que, dos grupos avaliados, poucos declaram alguma parceria com instituições privadas. De uma forma geral, está sendo produzido conhecimento muito valioso nas universidades brasileiras que pode ser trabalhado em prol de colocar novas alternativas de medicamentos e terapias veterinárias. Neste contexto, acredita-se que a maior cooperação entre universidades e empresas da área de saúde animal poderá beneficiar o mercado e a sociedade com novas soluções.
The goal of this research is to evaluate the state of art on innovation of the animal health sector, studying what has been produced and how, and the possible interactions with universities. The absence of published papers evaluating patents as well as the research groups that act, directly or indirectly, in the area of animal health have strengthened the need to initiate this research. Thus, through the survey and classification of patents registered in Brazil by animal health companies and public universities, as well as the evaluation of CNPq research groups, we sought to verify the scientific / technological production profile between the two main parties (public and private). In addition, this work pointed iut the existing demand and opportunity for innovation in animal health and an initial analysis of the level of interaction between research groups and companies was made. The results showed that the scientific - technological production profile of the two parties is distinct. It was observed that animal health companies showed greater registration of patents on the areas of biological and antiparasitic products, while universities had patent registration more distributed on the topics of interest for animal health. These observations were true for both, registered patents and research groups do not state a partnership with a private company in the animal health industry. In general, information is created in Brazilian universities, and it can be used on the development for new alternatives for veterinary medicines and therapies. In conclusion, it is possible that greater cooperation between universities and animal health companies could benefit the market and the society with new solutions.
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Bourély, Chrystèle. "Le manque de médicaments vétérinaires autorisés : un véritable problème de santé publique." Thesis, Montpellier 1, 2011. http://www.theses.fr/2011MON10029.

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Анотація:
L'industrie pharmaceutique vétérinaire doit satisfaire de nombreux besoins spécifiques à la grande diversité des espèces et des maladies animales, afin de répondre à la forte demande d'innovation, ainsi qu'au maintien sur le marché des "vieux" médicaments vétérinaires déjà autorisés. Le médicament vétérinaire fait l'objet d'une évaluation scientifique destinée à garantir sa qualité, son efficacité et sa sécurité. Les risques liés à son utilisation pour l'animal, mais aussi et surtout pour l'homme en tant qu'utilisateur dudit médicament et consommateur de denrées alimentaires d'origine animale, et pour l'environnement, ont conduit à un accroissement progressif et constant des exigences réglementaires. Le manque de médicaments vétérinaires autorisés pour les espèces animales et pour les indications thérapeutiques dites "mineures", conséquence de ces exigences réglementaires, est à l'origine du développement de pratiques à risques. La pratique licite des prescriptions "hors AMM" de médicaments vétérinaires par les docteurs en médecine vétérinaire, ainsi que les utilisations illicites de substances actives autorisées, susceptibles de porter atteinte à la santé animale, à la santé publique, et à l'environnement, représentent un véritable problème de santé publique
The veterinary pharmaceutical industry has to satisfy numerous specific needs due to the wide variety of the animal species and diseases, to answer the high demand of innovation as well as to maintain on the market the "old" veterinary medicines. The veterinary medicine is the object of a scientific evaluation, intended to guarantee its quality, its efficiency and its security.The risks related to its use for the animal but also and especially for the human (as user of the aforementioned medicine and as consumer of foodstuffs of animal origin), and for the environment, had leddriven to the regulatory requirements governing for veterinary medicinal products being increasingly tightened.The lack of authorized veterinary medicines for the "minors" animal species and therapeutic uses, consequence of these regulatory requirements, is at the origin of the development of risky practices. The licit practice of prescriptions " out of official authorization " of veterinarian medicines from doctors of veterinarian medicine, as well as the illicit uses of authorized active substances, susceptible to strike a blow at the animal health, at the public health, as well as the environment, represent a true public health issue
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Gomes, Joana Catarina Fernandes. "A medicina veterinária e a resistência aos antimicrobianos em contexto "one health” : a proposta de uma ferramenta de apoio à prescrição de antimicrobianos de uso veterinário." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2021. http://hdl.handle.net/10400.5/21413.

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Анотація:
Dissertação de Mestrado Integrado em Medicina Veterinária
RESUMO - A resistência antimicrobiana é um problema complexo e multifacetado que ameaça diferentes sectores da sociedade, nomeadamente a saúde humana, animal e ambiental, mas também a economia e segurança globais Desta forma, as abordagens atuais a esta ameaça centram-se sobretudo na tomada de medidas para preservar a eficácia contínua dos antimicrobianos existentes, assim como em tentar reduzir e/ou eliminar o seu uso inadequado. Este combate deve ser alicerçado numa abordagem que reconhece a interligação e interdependência entre os animais, o Homem e o meio ambiente, conhecida como One Health – “Uma Só Saúde”. Assim, para combater o uso indiscriminado de antimicrobianos é necessário desenvolver estratégias e ferramentas de controlo de forma a orientar e uniformizar procedimentos e auxiliar os Médicos Veterinários no contexto da prescrição e uso justificado de antimicrobianos. Perante o exposto, apresenta-se uma revisão da literatura que incidiu sobretudo nas bases bibliográficas Pubmed, Google Scholar e Science Direct, com o objetivo final de fornecer uma ferramenta para orientar e uniformizar a prescrição e uso justificado de antimicrobianos e apresentar uma síntese das recomendações e boas práticas sobre a temática envolvente. A ferramenta desenvolvida teve como sustentáculo um projeto realizado em primeira mão pelo Centro Europeu de Prevenção e Controlo de Doenças (ECDC), e que foi posteriormente adaptado pela Direção Geral da Saúde (DGS) e pelo Grupo de Interesse de Infeciologia: Colégio de Especialidade de Farmácia Hospitalar. Os resultados obtidos permitiram elaborar e propor quatro check-lists, duas direcionadas para a clínica de animais de companhia e duas para a clínica de espécies pecuárias. Ambas divididas em duas categorias, prescrição e uso justificado.
ABSTRACT - Antimicrobial resistance is a complex problem that threatens different sectors of society, including human, animal and environmental health, but also the economy and global security. Thus, current approaches to this threat focus mainly on taking measures to preserve the continued effectiveness of existing antimicrobials, as well as trying to reduce and / or eliminate their overuse. This fight must be based on an approach that recognizes the interconnection and interdependence between animals, man and the environment, known as One Health. To fight the indiscriminate use of antimicrobials, it is necessary to develop strategies and tools in order to control, guide and standardize procedures that could be used to support Veterinarians in the context of prescription and responsible use of veterinary antimicrobials. In view of the above, a review of the literature searched in the bibliographic databases Pubmed, Google Scholar and Science Direct is presented, with the ultimate goal of providing a tool to guide and standardize the prescription and responsible use of antimicrobials, but also summarizing recommendations and good practices that were used to create such tool. The developed tool was supported by a project carried out firsthand by the European Center for Disease Prevention and Control (ECDC), which was subsequently adapted by the Direção Geral de Saúde (DGS) and the Grupo de Interesse de Infecciologia: Colégio de Especialidade de Farmácia Hospitalar. The results obtained made it possible to develop and propose four checklists, two of them regarding companion animals, and the other two regarding large animals. Both divided into two categories, prescription and responsible use.
N/A
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9

Silva, Naira Tainá Rodrigues. "Proposta de um modelo para geração e análise das oportunidades de mercado e tecnológica para o desenvolvimento de produtos farmacêuticos veterinários." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-27082009-084931/.

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Анотація:
A geração e análise de oportunidades é o primeiro passo no desenvolvimento de inovação e da ação empreendedora. Identificar ou criar uma oportunidade por si só não basta, é preciso também conhecer o ciclo de inovação tecnológica no setor do negócio para analisar e verificar a viabilidade de implementação da inovação e sua probabilidade de sucesso. Conhecer as variáveis que compõem o ambiente geral e conhecer o ambiente específico da organização é fundamental para a identificação e verificação da viabilidade de uma idéia inovadora. Isso é possível através do comprometimento da organização como um todo no monitoramento de variáveis externas e internas utilizando ferramentas de inteligência competitiva e de prospecção que permitem não só ter um panorama da realidade atual das variáveis como também permitem a previsão da realidade futuramente. Essa prospecção futura facilita o planejamento em longo prazo da introdução e desempenho da oportunidade de inovação identificada. Este trabalho analisa diversos modelos e processos de geração e análise de oportunidades e os diversos fatores que afetam esse processo como recursos, capacidades, competências, criatividade, ambiente organizacional, aprendizagem e conhecimento. Também verifica as características da indústria farmacêutica veterinária e suas tendências de inovação que serviram de suporte para o desenvolvimento de um modelo de geração e análise de oportunidades aplicado ao setor farmacêutico veterinário. O modelo proposto implica na verificação das variáveis do ambiente externo e interno à empresa assim como de alguns fatores que influenciam o processo de geração e análise de oportunidades. Conforme resultados obtidos, o modelo é exeqüível, flexível e adaptável às necessidades e estratégias específicas de cada organização.
The generation and analysis of opportunities is the first step in the development of innovation and entrepreneurial action. Identify or create an opportunity is itself not enough, we should also know the cycle of technological innovation in the business sector to review and verify the feasibility of implementation of innovation and its likelihood of success. Knowing the variables that compose the general environment and know the specific environment of the organization is essential to identify and verify the feasibility of an innovative idea. This is possible through the commitment of the organization as a whole in the monitoring of external and internal variables using tools for competitive intelligence and prospecting which not only have an overview of the current reality of the variables but also allow the prediction of future reality. This forecast facilitates the planning of future long-term performance and the introduction of the opportunity for innovation identified. This work examines various models and processes of generation and analysis of opportunities and the various factors that affect this process as resources, capabilities, skills, creativity, organizational environment , learning and knowledge. Also verify the characteristics of the veterinary pharmaceutical industry and its trends of innovation that served to support the development of a model generation and analysis of opportunities applied to veterinary pharmaceuticals. The proposed model implies the verification of the variables of the external environment and internal variables to the company as well as some factors that influence the process of generation and analysis opportunities. In accordance with results obtained, the model is feasible, flexible and adaptable to specific needs and strategies of each organization.
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10

Borges, Liliana Isabel Ferreira. "Gestão do stock farmacêutico num hospital de fauna silvestre : apresentação de dois estudos de caso." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2012. http://hdl.handle.net/10400.5/5016.

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Анотація:
Dissertação de Mestrado Integrado em Medicina Veterinária
A subida constante dos custos da sociedade em geral e dos cuidados de saúde em particular, tanto a nível humano, como animal, requer a implementação de medidas que controlem as despesas, sendo essencial o não comprometimento da qualidade destes serviços. Os stocks são o grande investimento de qualquer serviço farmacêutico. Deste modo, uma eficiente gestão do inventário farmacêutico traduz-se no equilíbrio entre um adequado nível de produtos, um melhor serviço ao cliente e um menor custo. Diversos autores defendem que o conhecimento de conceitos e metodologias da gestão de stocks por parte dos médicos veterinários é essencial no processo de formulação do inventário farmacêutico, contribuindo, assim, para viabilidade económica das instituições veterinárias. Os alvos do presente estudo foram dois hospitais de fauna silvestre, ambos geridos por organizações não-governamentais e sem fins lucrativos, o GREFA (Majadahonda, Espanha) e o CERVAS (Gouveia, Portugal). Estes centros ilustram dois cenários opostos no que se refere à dimensão, equipamentos e número de animais assistidos, no entanto ambos bastante actuais no que respeita à estruturação dos centros de recuperação e reabilitação de fauna silvestre. Os processos de inventariação e compra de stocks foram descritos e analisados para os dois centros e a sua análise permitiu identificar limitações em ambos os casos, nomeadamente ao nível das fases de compra e armazenamento dos stocks. Este trabalho procurou demonstrar como a implementação de alguns dos princípios básicos da gestão de stocks, como sejam a redução do número de fornecedores, a redução do número de encomendas, boas práticas de recepção e armazenamento e o controlo das movimentações dos produtos, podem optimizar parte da despesa inerente ao stock farmacêutico.
ABSTRACT - Pharmaceutical inventory management of a wildlife hospital – two case studies - Due to the continued rising in the costs of society in general and healthcare in particular, at both human and animal level, it is essential the implementation of measures to control these ones without compromising the quality of the service. The stocks are a major investment for any pharmaceutical service therefore an efficient pharmaceutical inventory management is reflected in the balance of an appropriate level of products, better customer service and lower costs. Several authors highlight that the understanding of concepts and methodologies of inventory management on the part of veterinarians is crucial in the formulation of a pharmaceutical inventory, thus ensuring the economic viability of veterinary institutions. The targets of the study were two wildlife hospitals, managed by nongovernmental and nonprofit organizations, GREFA (Majadahonda, Spain) and CERVAS (Gouveia, Portugal). Both centers illustrate opposite scenarios, according to their size, equipment and treated animals, but very widespread in the structuring of recovery and rehabilitation centers of wild fauna. The process of inventorying and stocks purchasing were described and analyzed for the two centers. Their analysis identified limitations in both cases, particularly in the phases of purchasing and stock storing. This work demonstrates that the implementation of some of the basic principles of stock management, such as reducing the number of suppliers, reducing the number of orders, proper storage practices and the goods transfer control, could optimize the expenses inherent to the pharmaceutical stock.
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Книги з теми "Veterinary pharmaceutical"

1

Cobb, George P., and Philip N. Smith, eds. Evaluating Veterinary Pharmaceutical Behavior in the Environment. Washington, DC: American Chemical Society, 2013. http://dx.doi.org/10.1021/bk-2013-1126.

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Commission of the European Communities. Recasting of the Community pharmaceutical legislation: Veterinary legislation. Brussels: Commission of the European Communities, 1996.

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3

Crawford, Richard L. Selected web sites for biomedical, pharmaceutical, veterinary and animal sciences. Beltsville, Md: U.S. Dept. of Agriculture, National Agricultural Library, Animal Welfare Information Center, 1999.

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Animal Welfare Information Center (U.S.), ed. Selected web sites for biomedical, pharmaceutical, veterinary and animal sciences. Beltsville, Md. (10301 Baltimore Blvd., Beltsville 20705): U.S. Dept. of Agriculture, National Agricultural Library, Animal Welfare Information Center, 1999.

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5

Crawford, Richard L. Selected web sites for biomedical, pharmaceutical, veterinary and animal sciences. Beltsville, Md. (10301 Baltimore Blvd., Beltsville 20705): U.S. Dept. of Agriculture, National Agricultural Library, Animal Welfare Information Center, 1999.

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Crawford, Richard L. Selected web sites for biomedical, pharmaceutical, veterinary and animal sciences. Beltsville, Md. (10301 Baltimore Blvd., Beltsville 20705): U.S. Dept. of Agriculture, National Agricultural Library, Animal Welfare Information Center, 1999.

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7

Symposium, American Academy of Veterinary Pharmacology and Therapeutics. Veterinary pharmacology in the pharmaceutical industry: Proceedings of the ninth biennial symposium. [s.l.]: [s.n.], 1994.

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8

American Academy of Veterinary Pharmacology and Therapeutics Biennial Symposium (9th 1994 Kalamazoo, MI). Veterinary pharmacology in the pharmaceutical industry: Proceedings of the ninth biennial symposium Kalamazoo, MI, June 15-19, 1994. s.l: s.n., 1994.

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9

Pharmscience. The Australian contract manufacturing resource guide for the pharmaceutical and veterinary industries. 2nd ed. Caulfield East, Vic: Julex Pty Ltd, 2002.

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10

RVN, Green Nicola, and Lake Terry DVM, eds. Essential calculations for veterinary nurses and technicians. 2nd ed. Edinburgh: Elsevier Saunders, 2009.

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Частини книг з теми "Veterinary pharmaceutical"

1

Nahler, Gerhard. "Committee for Veterinary Medicinal Products (CVMP)." In Dictionary of Pharmaceutical Medicine, 32. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_245.

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2

Hahn, Gesine. "Target Animal Safety for Veterinary Pharmaceutical Products (VICH GL 43)." In Berichte zu Tierarzneimitteln 2009, 58–69. Basel: Birkhäuser Basel, 2009. http://dx.doi.org/10.1007/978-3-0346-0295-2_2.

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Kovensky, José, Eric Grand, and María Laura Uhrig. "Applications of Glycosaminoglycans in the Medical, Veterinary, Pharmaceutical, and Cosmetic Fields." In Industrial Applications of Renewable Biomass Products, 135–64. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-61288-1_5.

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4

Hamscher, Gerd. "Veterinary Pharmaceuticals." In Organic Pollutants in the Water Cycle, 99–120. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/352760877x.ch5.

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5

Donham, Kelley J. "Veterinary Pharmaceuticals." In Agricultural Medicine, 413–36. Hoboken, NJ: John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118647356.ch12.

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6

Chen, Chaoqi, Sheldon Hilaire, and Kang Xia. "Veterinary Pharmaceuticals, Pathogens and Antibiotic Resistance." In Animal Manure, 385–407. Madison, WI, USA: American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, 2020. http://dx.doi.org/10.2134/asaspecpub67.c26.

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7

Bartelt-Hunt, Shannon L. "Fate of Veterinary Pharmaceuticals in Agroecosystems." In Women in Water Quality, 173–84. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17819-2_10.

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8

Boxall, A. B. A., P. Kay, P. A. Blackwell, and L. A. Fogg. "Fate of Veterinary Medicines Applied to Soils." In Pharmaceuticals in the Environment, 165–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-09259-0_14.

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9

Waiser, Marley. "Aquatic Ecotoxicology of Veterinary Antibiotics and Pharmaceuticals." In Encyclopedia of Aquatic Ecotoxicology, 67–78. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-5704-2_7.

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10

Henderson, Keri L. D., and Joel R. Coats. "Veterinary pharmaceuticals in the environment: an introduction." In ACS Symposium Series, 3–7. Washington DC: American Chemical Society, 2009. http://dx.doi.org/10.1021/bk-2009-1018.ch002.

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Тези доповідей конференцій з теми "Veterinary pharmaceutical"

1

Queiroz, Nayhara B. D. F., and M. S. Amaral. "EFEITOS DE MICRO-HIDRATAÇÃO EM PROPRIEDADES CONFORMACIONAIS E ESPECTROSCÓPICAS DO ANTIBIÓTICO MARBOFLOXACINO." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020177.

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Marbofloxacin (MRB) is a fluoroquinolone used as a veterinary antibiotic. Some analytical methods of optical absorption are used for their determination in pharmaceutical formulations. Thus, we decided to study the electronic absorption spectrum of MRB in the UV-Vis region. For this, we use the TD-DFT, COSMO methods - based on the solvation continuum model - and micro-hydration. The interactions of MRB in both water and vacuum were simulated using computational modeling techniques. Ab initio quantum calculations were used to optimize the geometry of the isolated molecule and in the optical transition energy calculations. The solute-solvent simulation was performed with the Molecular Dynamics technique in the NpT ensemble using a temperature of 300 K in the Amber computer package. The system balance was monitored by Root Mean Square Deviation. The analyzes of the absorption spectra were carried out using the micro-hydration method. This method involved the use of different numbers, from 2 to 8, of the water molecules of the first solvation layer to calculate transition energies. The transition energies were calculated using the TD-DFT method at the theory level B3LYP / 6-311G using together the Conductor-like Screening Model solvation model that assesses the effect of the solvent implicit in the system. For all micro-hydration systems, energy absorption decreases as the wavelength increases. Observing the values it is noticed that there was a deviation in the absorption spectrum 325.4 nm (in the isolated molecule) to 274.1 (with the addition of water). These values are within the experimental ones where we have the bands with maximum absorption at 268 nm and 335 nm.
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Pierce, Larry, and Honglin Shi. "Evaluation of Veterinary Pharmaceuticals and Iodine for Use as a Groundwater Tracer in Hydrologic Investigation of Contamination Related to Dairy Cattle Operations." In National Cave and Karst Research Institute Symposium 5. University of South Florida Tampa Library, 2015. http://dx.doi.org/10.5038/9780991000951.1013.

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Звіти організацій з теми "Veterinary pharmaceutical"

1

van Asselt, E. D., M. G. Pikkemaat, R. G. Hobe, N. P. Meijer, H. van Egmond, and P. Bikker. Potential occurrence of veterinary pharmaceuticals in animal by-products : an inventory of authorised substances in non-EU countries that are not allowed within the EU. Wageningen: Wageningen Food Safety Research, 2021. http://dx.doi.org/10.18174/558162.

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Evidence Synthesis and Meta-Analysis for Drug Safety. Council for International Organizations of Medical Sciences (CIOMS), 2016. http://dx.doi.org/10.56759/lela7055.

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At any point in the drug development process, systematic reviews and meta-analysis can provide important information to guide the future path of the development programme and any actions that might be needed in the post-marketing setting. This report gives the rationale for why and when a meta-analysis should be considered, all in the context of regulatory decision-making, and the tasks, data collection, and analyses that need to be carried out to inform those decisions. -- There is increasing demand by decision-makers in health care, the biopharmaceutical industry, and society at large to have access to the best available evidence on benefits and risks of medicinal products. The best strategy will take an overview of all the evidence and where it is possible and sensible, combine the evidence and summarize the results. For efficacy, the outcomes generally use the same or very similar predefined events for each of the trials to be included. Most regulatory guidance and many Cochrane Collaboration reviews have usually given more attention to assessment of benefits, while issues around combining evidence on harms have not been as well-covered. However, the (inevitably) unplanned nature of the data on safety makes the process more difficult. -- Combining evidence on adverse events (AEs), where these were not the focus of the original studies, is more challenging than combining evidence on pre-specified benefits. This focus on AEs represents the main contribution of the current CIOMS X report. The goal of the CIOMS X report is to provide principles on appropriate application of meta-analysis in assessing safety of pharmaceutical products to inform regulatory decision-making. This report is about meta-analysis in this narrow area, but the present report should also provide conceptually helpful points to consider for a wider range of applications, such as vaccines, medical devices, veterinary medicines or even products that are combinations of medicinal products and medical devices. -- Although some of the content of this report describes highly technical statistical concepts and methods (in particular Chapter 4), the ambition of the working group has been to make it comprehensible to non-statisticians for its use in clinical epidemiology and regulatory science. To that end, Chapters 3 and 4, which contain the main technical statistical aspects of the appropriate design, analysis and reporting of a meta-analysis of safety data are followed by Chapter 5 with a thought process for evaluating the findings of a meta-analysis and how to communicate these.
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