Готові списки джерел за темами / UvrC

Добірка наукової літератури з теми "UvrC"

Автор: Grafiati
Опубліковано: 6 вересня 2023

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Статті в журналах з теми "UvrC"

1

Moolenaar, Geri F., Celine Moorman, and Nora Goosen. "Role of the Escherichia coli Nucleotide Excision Repair Proteins in DNA Replication." Journal of Bacteriology 182, no. 20 (October 15, 2000): 5706–14. http://dx.doi.org/10.1128/jb.182.20.5706-5714.2000.

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ABSTRACT DNA polymerase I (PolI) functions both in nucleotide excision repair (NER) and in the processing of Okazaki fragments that are generated on the lagging strand during DNA replication.Escherichia coli cells completely lacking the PolI enzyme are viable as long as they are grown on minimal medium. Here we show that viability is fully dependent on the presence of functional UvrA, UvrB, and UvrD (helicase II) proteins but does not require UvrC. In contrast, ΔpolA cells grow even better when theuvrC gene has been deleted. Apparently UvrA, UvrB, and UvrD are needed in a replication backup system that replaces the PolI function, and UvrC interferes with this alternative replication pathway. With specific mutants of UvrC we could show that the inhibitory effect of this protein is related to its catalytic activity that on damaged DNA is responsible for the 3′ incision reaction. Specific mutants of UvrA and UvrB were also studied for their capacity to support the PolI-independent replication. Deletion of the UvrC-binding domain of UvrB resulted in a phenotype similar to that caused by deletion of the uvrC gene, showing that the inhibitory incision activity of UvrC is mediated via binding to UvrB. A mutation in the N-terminal zinc finger domain of UvrA does not affect NER in vivo or in vitro. The same mutation, however, does give inviability in combination with the ΔpolA mutation. Apparently the N-terminal zinc-binding domain of UvrA has specifically evolved for a function outside DNA repair. A model for the function of the UvrA, UvrB, and UvrD proteins in the alternative replication pathway is discussed.
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2

LeCuyer, Brian E., Alison K. Criss, and H. Steven Seifert. "Genetic Characterization of the Nucleotide Excision Repair System of Neisseria gonorrhoeae." Journal of Bacteriology 192, no. 3 (November 20, 2009): 665–73. http://dx.doi.org/10.1128/jb.01018-09.

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ABSTRACT Nucleotide excision repair (NER) is universally used to recognize and remove many types of DNA damage. In eubacteria, the NER system typically consists of UvrA, UvrB, UvrC, the UvrD helicase, DNA polymerase I, and ligase. In addition, when DNA damage blocks transcription, transcription-repair coupling factor (TRCF), the product of the mfd gene, recruits the Uvr complex to repair the damage. Previous work using selected mutants and assays have indicated that pathogenic Neisseria spp. carry a functional NER system. In order to comprehensively examine the role of NER in Neisseria gonorrhoeae DNA recombination and repair processes, the predicted NER genes (uvrA, uvrB, uvrC, uvrD, and mfd) were each disrupted by a transposon insertion, and the uvrB and uvrD mutants were complemented with a copy of each gene in an ectopic locus. Each uvr mutant strain was highly sensitive to UV irradiation and also showed sensitivity to hydrogen peroxide killing, confirming that all of the NER genes in N. gonorrhoeae are functional. The effect of RecA expression on UV survival was minor in uvr mutants but much larger in the mfd mutant. All of the NER mutants demonstrated wild-type levels of pilin antigenic variation and DNA transformation. However, the uvrD mutant exhibited higher frequencies of PilC-mediated pilus phase variation and spontaneous mutation, a finding consistent with a role for UvrD in mismatch repair. We conclude that NER functions are conserved in N. gonorrhoeae and are important for the DNA repair capabilities of this strict human pathogen.
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3

Humann, Jodi L., Hope T. Ziemkiewicz, Svetlana N. Yurgel, and Michael L. Kahn. "Regulatory and DNA Repair Genes Contribute to the Desiccation Resistance of Sinorhizobium meliloti Rm1021." Applied and Environmental Microbiology 75, no. 2 (November 21, 2008): 446–53. http://dx.doi.org/10.1128/aem.02207-08.

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ABSTRACT Sinorhizobium meliloti can form a nitrogen-fixing symbiotic relationship with alfalfa after bacteria in the soil infect emerging root hairs of the growing plant. To be successful at this, the bacteria must be able to survive in the soil between periods of active plant growth, including when conditions are dry. The ability of S. meliloti to withstand desiccation has been known for years, but genes that contribute to this phenotype have not been identified. Transposon mutagenesis was used in combination with novel screening techniques to identify four desiccation-sensitive mutants of S. meliloti Rm1021. DNA sequencing of the transposon insertion sites identified three genes with regulatory functions (relA, rpoE2, and hpr) and a DNA repair gene (uvrC). Various phenotypes of the mutants were determined, including their behavior on several indicator media and in symbiosis. All of the mutants formed an effective symbiosis with alfalfa. To test the hypothesis that UvrC-related excision repair was important in desiccation resistance, uvrA, uvrB, and uvrC deletion mutants were also constructed. These strains were sensitive to DNA damage induced by UV light and 4-NQO and were also desiccation sensitive. These data indicate that uvr gene-mediated DNA repair and the regulation of stress-induced pathways are important for desiccation resistance.
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4

Hall, Barry G. "Genetics of selection-induced mutations: I. uvrA, uvrB, uvrC, and uvrD are selection-induced specific mutator loci." Journal of Molecular Evolution 40, no. 1 (January 1995): 86–93. http://dx.doi.org/10.1007/bf00166599.

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5

Thomas, D. C., M. Levy, and A. Sancar. "Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli." Journal of Biological Chemistry 260, no. 17 (August 1985): 9875–83. http://dx.doi.org/10.1016/s0021-9258(17)39318-3.

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6

Selby, Christopher P., Laura A. Lindsey-Boltz, Yanyan Yang, and Aziz Sancar. "Mycobacteria excise DNA damage in 12- or 13-nucleotide-long oligomers by prokaryotic-type dual incisions and performs transcription-coupled repair." Journal of Biological Chemistry 295, no. 50 (October 21, 2020): 17374–80. http://dx.doi.org/10.1074/jbc.ac120.016325.

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In nucleotide excision repair, bulky DNA lesions such as UV-induced cyclobutane pyrimidine dimers are removed from the genome by concerted dual incisions bracketing the lesion, followed by gap filling and ligation. So far, two dual-incision patterns have been discovered: the prokaryotic type, which removes the damage in 11–13-nucleotide-long oligomers, and the eukaryotic type, which removes the damage in 24–32-nucleotide-long oligomers. However, a recent study reported that the UvrC protein of Mycobacterium tuberculosis removes damage in a manner analogous to yeast and humans in a 25-mer oligonucleotide arising from incisions at 15 nt from the 3´ end and 9 nt from the 5´ end flanking the damage. To test this model, we used the in vivo excision assay and the excision repair sequencing genome-wide repair mapping method developed in our laboratory to determine the repair pattern and genome-wide repair map of Mycobacterium smegmatis. We find that M. smegmatis, which possesses homologs of the Escherichia coli uvrA, uvrB, and uvrC genes, removes cyclobutane pyrimidine dimers from the genome in a manner identical to the prokaryotic pattern by incising 7 nt 5´ and 3 or 4 nt 3´ to the photoproduct, and performs transcription-coupled repair in a manner similar to E. coli.
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7

McCready, S., and L. Marcello. "Repair of UV damage in Halobacterium salinarum." Biochemical Society Transactions 31, no. 3 (June 1, 2003): 694–98. http://dx.doi.org/10.1042/bst0310694.

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Halobacterium is one of the few known Archaea that tolerates high levels of sunlight in its natural environment. Photoreactivation is probably its most important strategy for surviving UV irradiation and we have shown that both of the major UV photoproducts, cyclobutane pyrimidine dimers (CPDs) and (6–4) photoproducts, can be very efficiently repaired by photoreactivation in this organism. There are two putative photolyase gene homologues in the published genome sequence of Halobacterium sp. NRC-1. We have made a mutant deleted in one of these, phr2, and confirmed that this gene codes for a CPD photolyase. (6–4) photoproducts are still photoreactivated in the mutant so we are currently establishing whether the other homologue, phr1, codes for a (6–4) photolyase. We have also demonstrated an excision repair capacity that operates in the absence of visible light but the nature of this pathway is not yet known. There is probably a bacteria-type excision-repair mechanism, since homologues of uvrA, uvrB, uvrC and uvrD have been identified in the Halobacterium genome. However, there are also homologues of eukaryotic nucleotide-excision-repair genes (Saccharomy cescerevisiae RAD3, RAD25 and RAD2) so there may be multiple repair mechanisms for UV damage in Halobacterium.
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8

SaiSree, L., Manjula Reddy, and J. Gowrishankar. "lon Incompatibility Associated with Mutations Causing SOS Induction: Null uvrD Alleles Induce an SOS Response in Escherichia coli." Journal of Bacteriology 182, no. 11 (June 1, 2000): 3151–57. http://dx.doi.org/10.1128/jb.182.11.3151-3157.2000.

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ABSTRACT The uvrD gene in Escherichia coli encodes a 720-amino-acid 3′-5′ DNA helicase which, although nonessential for viability, is required for methyl-directed mismatch repair and nucleotide excision repair and furthermore is believed to participate in recombination and DNA replication. We have shown in this study that null mutations in uvrD are incompatible withlon, the incompatibility being a consequence of the chronic induction of SOS in uvrD strains and the resultant accumulation of the cell septation inhibitor SulA (which is a normal target for degradation by Lon protease). uvrD-lonincompatibility was suppressed by sulA,lexA3(Ind−), or recA (Def) mutations. Other mutations, such as priA, dam,polA, and dnaQ (mutD) mutations, which lead to persistent SOS induction, were also lonincompatible. SOS induction was not observed in uvrC andmutH (or mutS) mutants defective, respectively, in excision repair and mismatch repair. Nor wasuvrD-mediated SOS induction abolished by mutations in genes that affect mismatch repair (mutH), excision repair (uvrC), or recombination (recB andrecF). These data suggest that SOS induction inuvrD mutants is not a consequence of defects in these three pathways. We propose that the UvrD helicase participates in DNA replication to unwind secondary structures on the lagging strand immediately behind the progressing replication fork, and that it is the absence of this function which contributes to SOS induction inuvrD strains.
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9

Tang, M. S., and L. Ross. "Single-strand breakage of DNA in UV-irradiated uvrA, uvrB, and uvrC mutants of Escherichia coli." Journal of Bacteriology 161, no. 3 (1985): 933–38. http://dx.doi.org/10.1128/jb.161.3.933-938.1985.

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10

Thakur, Manoj, Sugith Badugu, and Kalappa Muniyappa. "UvrA and UvrC subunits of the Mycobacterium tuberculosis UvrABC excinuclease interact independently of UvrB and DNA." FEBS Letters 594, no. 5 (November 24, 2019): 851–63. http://dx.doi.org/10.1002/1873-3468.13671.

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Дисертації з теми "UvrC"

1

Walters, Robin George. "The organisation, expression and function of the UVRC gene of Escherichia coli." Thesis, University of Liverpool, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237558.

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2

Rizzini, Luca [Verfasser], and Roman [Akademischer Betreuer] Ulm. "UVR8: a plant UV-B photoreceptor = UVR8: ein pflanzlicher UV-B Photorezeptor." Freiburg : Universität, 2011. http://d-nb.info/1123457891/34.

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3

Findlay, Kirsten. "UVR8 function in a natural solar environment." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/8264/.

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4

Rose, Robert Michael. "Computer control of gelation in UVPC compounding." Thesis, University of Bradford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292425.

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5

Albrighton, Rachel Mary. "Mutational analysis of the DNA repair protein, UvrA." Thesis, University of Bristol, 2006. http://hdl.handle.net/1983/9fcda510-baf1-44c9-8eb5-f03b5c5a9ba8.

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6

PREVOST, DONALD. "Retines artificielles stochastiques : algorithmes et mise en uvre." Paris 11, 1995. http://www.theses.fr/1995PA112505.

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Cette these traite de problemes de vision bas-niveau, lesquels entrent dans la classe des problemes inverses mal-poses au sens mathematique. Leur resolution est envisagee sous l'angle de l'approche bayesienne sur champ de markov. Specifiquement, nous etudions les algorithmes d'optimisation applicables a des fonctions d'energie semi-quadratiques, telles que rencontrees en vision bas-niveau (detection de contours, segmentation des textures, determination de mouvement ou stereovision). Ces energies sont definies sur un champ de markov couple. Notre premier objectif est de determiner des approches algorithmiques avantageuses selon les criteres de l'optimalite de la solution ; de la qualite de la restauration, des perspectives de parallelisation et de realisation materielle. Notre demarche consiste a considerer une tache simple: la restauration d'images avec prise en compte des discontinuites. Nous avons compare differents algorithmes dedies a cette tache, puis nous avons propose une methode stochastique, simple et parallelisable, que nous avons appelee relaxation quasi-statique (rqs). Le second objectif releve de l'implantation materielle optoelectronique. Nous proposons une architecture parallele de mise en uvre pour l'algorithme rqs. Celle-ci reflete la structure du champ de markov couple: elle est base sur l'operation conjuguee d'un reseau de resistance stochastique et d'un module binaire. Afin de demontrer la faisabilite de machines d'optimisation stochastique operant a cadence video, nous avons concu et teste un systeme realisant des calculs de monte-carlo sur le probleme du verre de spin. Ce systeme utilise un circuit integre cmos optoelectronique (collaboration avec l'ief, contrat dret n 92-139) et un generateur optique de figures de speckle
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7

Wright, Caradee Yael, and n/a. "UVR exposure of NZ schoolchildren." University of Otago. Dunedin School of Medicine, 2007. http://adt.otago.ac.nz./public/adt-NZDU20070817.093312.

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Excess exposure to solar ultraviolet radiation (UVR) is the only readily modifiable skin cancer risk factor, and childhood exposure is implicated in melanoma aetiology. To assist the design and evaluation of child sun protection interventions in the school and community context, this first comprehensive study used electronic monitors to record time-stamped, second-by-second UVR exposure of 325 children (from 28 randomly selected New Zealand primary schools) who kept a diary record of concurrent activities and sun-protective practices and completed a sun-related knowledge, attitudes and usual behaviours questionnaire. School principals and Health promoters (HPs) were interviewed about school and community sun protection efforts. Using the Haddon matrix and Ottawa Charter of Health Promotion to guide research, four potential domains of influence were identified: the physical and social environments, protective products, and host (child). Two key outcomes identified were child UVR exposure and sun-protective practices. A path model was developed where potential influences on these outcomes included school, community, host factors (demographics, skin type, sun-related attitudes, and sun-related knowledge), and pattern of concurrent outdoor activity. Seven specific hypotheses were defined to investigate the effects of host, school and community factors on UVR exposure, sun-protective practices, and sun-related knowledge, attitudes and behaviours. To test for the effects of host factors, day of the week and activity on UVR exposure and sun-protective practices, linear mixed models containing these factors and interactions between Year level-sex, activity-Year level and activity-sex, accounting for clustering within schools and allowing for repeated measures, were applied. Logistic regression with a random school effect was used to assess differences in scored student questionnaire items. Structural equation modelling was implemented to consider associations between sun-related knowledge, attitudes and behaviours, and other explanatory factors for variations in UVR exposure and sun-protective practices. Three of the seven specific hypotheses were supported. There were statistically significant differences in UVR exposure by sex, skin type, day of the week and activity, and sex-activity and Year level-activity interactions. Passive pursuits were associated with the highest UVR exposure rates compared to outdoor active, travel and unclassified pursuits. There were statistically significant differences in sun-protective practices by sex, ethnicity and skin type, and sex-activity and Year level-activity interactions. Girls tended to have higher sun protection scores than boys, but were more likely to sunbathe and use sunscreen. Children identifying with Pacific Island ethnicities had higher scores than children with other ethnicities, and children with Fitzpatrick skin types I and II had higher scores than children with skin types III, IV and V. School and community factors were not associated with UVR exposure, sun-protective practices, sun-related knowledge, attitudes and behaviours, but school and HPs� scores were relatively high, reflecting the significant time and effort spent promoting youth sun protection. Trends for Year level indicated that whereas child sun-related knowledge increased with Year level, attitudes and behaviours supportive of sun protection declined. When considering sun-related knowledge, attitudes and behaviours simultaneously, knowledge was only significantly associated with behaviours when mediated by attitudes. The study findings have implications for child sun protection interventions.
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8

Carsberg, Catherine Jane. "Mechanisms underlying UVR-induced melanogenesis." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385314.

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9

Zhang, Zixin. "UVR transmission through clothing fabrics." Thesis, Queensland University of Technology, 1994. https://eprints.qut.edu.au/37170/1/37170_Zhang_1994.pdf.

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A new fabric transmission measuring system (FTMS) utilising a solar UV simulator and a broad band radiometer, has been designed and developed for fast assessment of the protection levels of clothing fabrics against the biological damage caused by sunlight. The radiometer has a spectral response similar to the erythema action spectrum for human skin. The advantages of the FTMS are simplicity, reliability, low cost and, most importantly, time-efficiency. It has a capacity to process sixty-five clothing samples in about twenty-five minutes. The FTMS was calibrated against a spectroradiometer. The error of the results obtained by the FTMS is estimated within ±8%. The FTMS was employed to study the effects of the parameters and conditions of clothing fabrics on the result of the erythema effective transmittance, i.e. the transmittance of irradiance weighted with the erythema action spectrum for human skin. It was observed that weave structure of clothing fabrics could change the transmittance by up to 11.2 times even though all other factors such as the colour and the dryness condition were maintained at constant. The variations of transmittance with various colours were up to about 200% for polyester(65%)/cotton(35%) samples, and 600% for cotton samples in the studies. A variation as high as about 20 times in transmittance was recorded by stretching lycra clothing fabrics. Wetness of clothing fabrics could change the erythema effective transmittance in either directions, i.e. increase and decrease, depending on the types of clothing fabrics. An increase of transmittance of about 3.1 times and a decrease of about 70% due to the wetness conditions were observed. A model was proposed to correlate the UV transmittance and the characteristics of clothing fabrics. The model was preliminarily tested and a correlation coefficient of 0.902 for the UV transmittance measured with the FTMS and the UV transmittance calculated by the model was obtained. The UV transmission through clothing fabrics is not only determined by the uncovered area of clothing fabrics, but also by the UVR scattering of clothing fabrics. Taking into account of the effects of UVR scattering by clothing fabrics would improve the results.
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10

LEGENDRE, STEPHANE. "Modeles en dynamique des populations mise en uvre informatique." Paris 6, 1996. http://www.theses.fr/1996PA066744.

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Le devenir des populations depend des capacites intrinseques des individus a survivre et a se reproduire et de leurs interactions avec l'environnement (climat, ressources, autres populations). Une synthese des modeles mathematiques en temps discret integrant ces facteurs est faite et la realisation du logiciel ulm (unified life models), destine a etudier ces modeles de facon tres generale, est exposee. Des quantites fondamentales telles que le taux de croissance et la probabilite d'extinction peuvent etre calculees, permettant au biologiste de repondre a des questions pratiques (gestion, conservation des especes) et theoriques (demographie evolutive). 1) dans le modele de base, les individus sont decrits par le cycle de vie qui integre les traits d'histoire de vie. Aux transitions entre les stades du cycle sont associes les parametres demographiques (survie, reproduction). La dynamique de la population structuree par les stades est connue par iteration du cycle dans le temps. Ce modele conduit au formalisme matriciel et des proprietes algebriques de la matrice (valeurs propres, vecteurs propres) donnent des informations demographiques essentielles. La stochasticite demographique est introduite en considerant que les transitions du cycle de vie sont des realisations de lois de probabilite a valeurs entieres. Les composantes regulatrices (densite-dependance) et aleatoires (stochasticite environnementale) sont prises en compte en alterant les parametres demographiques par des fonctions appropriees. 2) le fonctionnement du programme est explicite, notamment la gestion symbolique des objets. Les modeles, definis a l'aide d'un langage simple, peuvent etre etudies interactivement au moyen de commandes qui produisent des resultats numeriques et des representations graphiques. 3) des applications biologiques variees sont presentees : strategies de reintroduction du vautour fauve, etude d'une population de viperes en declin, interactions du virus c de la drosophile et de son hote.
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Книги з теми "UvrC"

1

chet, Caroline Fre. Mettre en ¿uvre le Six Sigma. Paris: E d. d'Organisation, 2005.

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2

ve, Dewulf Genevie, ed. L' ¿uvre d'art: Balzac, Proust, Rilke. Nancy: Presses universitaires de Nancy, 1993.

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3

Franzheim, Elizabeth. Elizabeth Franzheim: L' uvre, 1965-1985. Paris: Paris Art Center, 1985.

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4

Roethlisberger, Marcel. Tout l' uvre peint de Claude Lorrain. Paris: Flammarion, 1986.

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5

Sidaner, Yann Farinaux-Le. Le Sidaner: L' uvre peint et gravé. (Monaco): A. Sauret, 1989.

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6

University of Victoria (B.C.). Alumni Association., ed. A multitude of the wise: UVic remembered. Victoria, B.C: Alumni Association of the University of Victoria, 1993.

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7

Musée des arts décoratifs (Paris, France). Chefs-d' uvre du Musée des arts décoratifs. Paris: Le Musée des arts décoratifs, 1985.

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8

Rahaniotis, Angela. Appetizers. Montreal: Brimar, 1995.

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9

Zhiĭdėė, Shuumryn. Uvc aĭmgiĭn ėru̇u̇liĭg khamgaalakhyn tu̇u̇khėn tovchoon. Ulaanbaatar: Soëmbo, 2005.

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10

Wegman, William. William Wegman: L'¿uvre photographique = photographic works, 1969-1976. Limoges: Fonds re gional d'art contemporain du Limousin, 1991.

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Частини книг з теми "UvrC"

1

Yadav, Shivam, and Neelam Atri. "Discovery of UVR8." In UV-B Radiation, 279–88. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119143611.ch14.

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2

Ruparel, Meeta. "UVC Mediairguard™." In 5th World Congress on Disaster Management: Volume III, 299–307. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003341963-39.

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3

Liu, Yan, and Xi Huang. "Isolation of UVR8 Protein Complexes." In Methods in Molecular Biology, 33–40. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1370-2_4.

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4

Singh, Jyoti. "UVR-Induced Skin Cancer." In Skin Aging & Cancer, 41–46. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2541-0_4.

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5

Dwivedi, Ashish, Amit Kumar Tripathi, Jyoti Singh, and Manish Kumar Pal. "Ultraviolet Radiation (UVR): An Introduction." In Photocarcinogenesis & Photoprotection, 1–8. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-5493-8_1.

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Chopra, Deepti, Dhanananajay Kumar, Divya Dubey, Jyoti Singh, Ajeet Kumar Srivastav, and Kailash Chand Gupta. "UVR and Vitamin D Synthesis." In Skin Aging & Cancer, 71–78. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2541-0_7.

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Chopra, Deepti, Jyoti Singh, Ajeet Kumar Srivastav, Divya Dubey, Ratan Singh Ray, and Kailash Chand Gupta. "Protective Role of Phytochemicals Against UVR." In Photocarcinogenesis & Photoprotection, 129–39. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-5493-8_12.

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Yadav, Neera, Amit Kumar Tripathi, and Monisha Banerjee. "UVR-Induced Epigenetic Regulation and Photocarcinogenesis." In Photocarcinogenesis & Photoprotection, 9–13. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-5493-8_2.

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Reddy Gade, Vishal, Deep Seth, Manish Kumar Agrawal, and Bhaskar Tamma. "Development of Autonomous UVC Disinfectant Robot." In Digital Human Modeling and Applications in Health, Safety, Ergonomics and Risk Management. AI, Product and Service, 135–51. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-77820-0_11.

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Chatterjee, Antra, Alok Kumar Shrivastava, Sonia Sen, Shweta Rai, Shivam Yadav, Ruchi Rai, Shilpi Singh, and LC Rai. "UVR8 Signalling, Mechanism and Integration with other Pathways." In UV-B Radiation, 289–307. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119143611.ch15.

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Тези доповідей конференцій з теми "UvrC"

1

Fredes, Pablo, Ulrich Raff, Cristian Soto, and Pratibha Sharma. "Empirical and Theoretical study of the Thermal Performance of High Power UVC LEDs." In Optical Devices and Materials for Solar Energy and Solid-state Lighting. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/pvled.2022.pvth3f.1.

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UVC LEDs exhibit high junction temperature (T J ) and voltage sensitivity, which influences their radiant power and lifetimes. This study of 275nm, 3-PAD UVC LEDs can be useful to estimate T J and emphasize the need for optimal thermal management.
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Tharwat, Marwa, Maram Alsofiani, Sereen Bahdad, Ghaida Alyousfi, and Heba Alebbie. "UVC Sanitizing Smart Kit." In 2022 5th International Conference on Computing and Informatics (ICCI). IEEE, 2022. http://dx.doi.org/10.1109/icci54321.2022.9756125.

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Furtado, Janaise Mesquita Bueno, Charlene Nascimento Dos Santos Trindade, Everton Granemann Souza, Mário Lúcio Moreira, and Chiara Das Dores Nascimento. "EFICÁCIA DA RADIAÇÃO UVC EM STAPHYLOCOCCUS AUREUS." In II Congresso Brasileiro de Biotecnologia On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2022. http://dx.doi.org/10.51189/conbiotec/05.

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Introdução: A luz UV cobre um espectro eletromagnético entre 200 a 400nm sendo subdividida em quatro regiões: UVA (315 a 400nm), UVB (280 a 315nm), UVC (200 a 280nm) e far UVC (207 a 222nm). A luz UVC é conhecida por apresentar um alto efeito germicida, inativando um amplo espectro de microorganismos, como fungos, vírus e bactérias, através da formação de dímeros de pirimidinas, que são danos nas moléculas de DNA ou RNA, que comprometem a replicação desses seres microscópicos. Estudos recentes mostram que, dentro de um ambiente hospitalar, até 5% das bactérias são do tipo Staphylococcus aureus, devido a sua presença na pele de grande parte das pessoas. Na maioria dos casos, a S. Aureus não causa perigo, no entanto quando atinge a corrente sanguínea pode causar pneumonia (infecção pulmonar) ou endocardite (infecção das válvulas cardíacas). A dose letal de UVC para inativar a S. Aureus já é conhecida, entretanto existem variações na literatura. Objetivos: O presente trabalho tem como objetivo determinar a dose letal, por irradiação direta, de uma lâmpada tubular UVC de 36 W, e comprimento de onda de pico em 254nm, em colônias de Staphylococcus aureus (ATCC 25923). Materiais e métodos: Para execução do experimento, foi efetuada uma diluição seriada (1:1000000), a partir da escala 0.5 Mcfarland. Então, um inóculo de 100 µL foi semeado em placas de ágar padrão as quais foram irradiadas com tempos variando entre 3 e 20 segundos. Imediatamente após, as colônias foram colocadas em uma estufa por 24h e 48h para crescimento. Resultados: Os resultados indicam que 10 segundos de irradiação direta, equivalentes a uma dose de 3,17mJ/cm2, reduzem cerca de 95% das colônias bacterianas. Conclusão: Os experimentos realizados comprovam que o uso da radiação UVC de 254nm é eficaz para inativação de microorganismos, no entanto, a dose encontrada encontra-se mais próxima do limite inferior encontrado na literatura, que varia entre os valores de 2,0 e 6,6 mJ/cm2.
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4

Conan, R., C. Bradley, P. Hampton, O. Keskin, A. Hilton, and C. Blain. "UVic Woofer-Tweeter Test Bed: Status and Plans." In Adaptive Optics: Methods, Analysis and Applications. Washington, D.C.: OSA, 2007. http://dx.doi.org/10.1364/aopt.2007.ama7.

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Mamidi, Rachana, Arvin Sharifbaev, Shivani P. Patel, Matthew Gacura, Gary Vanderlaan, Xiaoxu Ji, and Davide Piovesan. "Effect of Liner Albedo on UVC Irradiation Control." In ASME 2022 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/imece2022-95797.

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Abstract Ultraviolet germicidal irradiation (UVGI) has been used successfully for the sterilization of tools and whole environments. The advantages of this method are numerous. There does not need to be any physical contact with the artifact to be sterilized; the procedure is quite fast and allows for covering large areas. As a drawback, the cost of these systems is often still prohibitive, and the necessity of the light to hit the surface to be effective might leave residual contamination in the shadowed areas within lumens. To avoid potential shadows, the internal surface of an environment can be covered with specific reflective materials appropriate for the wavelength of the irradiation source. We designed a cost-efficient sterilization chamber that uses UVC for decontamination (SHIVA, Small High-Intensity ultra-Violet Antimicrobial chamber.). The design focuses on a decontamination chamber easy to manufacture for rapid deployment. The device can also be used by the general public for sanitizing non washable materials. We tested the control of irradiation dose, based on different types of materials lining the internal part of the sterilization chamber. The reflectance of the material in the UVC Spectrum was critical for the increase of irradiation dose at the target. We tested 3 lining materials (Teflon, Aluminum, and Vinyl) using an 8W UVGI fluorescent lamp in the Ultra Violet-C (UVC) wavelength range, with peak irradiation at 254.3 nm. Variations between linings could provide a variation in dosage up to 30%. We observed that Vinyl reflectivity in the UVC range is close to 90% and provides the best compromise between the price of the lining, and the final irradiation dose provided to the samples. An increase in total irradiation allows for a more energy-efficient system that could utilize batteries rather than electrical energy from an outlet; hence improving portability.
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Kou, Yang, Xiu-hua Fu, Dong-mei Liu, Hao Zhu, and He-yue Tang. "Study on UVC ultraviolet filter film." In 6th International Symposium on Advanced Optical Manufacturing and Testing Technologies (AOMATT 2012), edited by Li Yang, Eric Ruch, and Shengyi Li. SPIE, 2012. http://dx.doi.org/10.1117/12.971446.

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7

González, Anabelis, William Pérez, Israel Centella, Samuel Finol, and Erick Ramos. "DISPOSITIVO UVC DISHES AND CULTLERY SANITATOR." In V Congreso de Investigación Desarrollo en Innovación de la Universidad Internacional de Ciencia y Tecnología. Universidad Internacional de Ciencia y Tecnología, 2021. http://dx.doi.org/10.47300/978-9962-5599-8-6-26.

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El problema que enfrenta la humanidad con mayor urgencia es la pandemia por el virus Civid-19. En tal sentido, los científicos se apresuran a encontrar una vacuna para atender la urgencia, pero, desde la academia, se debe buscar formas alternas de atender otras necesidades de las sociedades, tal es el caso de la sanitización o desinfección de los utensilios comunes para la alimentación y más específicamente los platos y cubiertos no desechables, que son los que más comúnmente se utilizan en los hogares de menor recurso en general, pero también en restaurantes, hoteles, centros de salud, comedores escolares y otros. El objetivo de esta investigación es desarrollar un prototipo de un dispositivo que desinfecte platos y cubiertos, mediante el uso de luz Ultravioleta tipo “C” (UVC), La luz ultravioleta es una luz que se ha empleado hace más de un siglo para la desinfección de alimentos, agua, la estética y hasta su aplicación en la medicina. Por medio de la Luz UV se ha logrado grandes contribuciones a la salud de muchas personas. Con una metodología de investigación aplicada. Por ser una investigación en desarrollo, el resultado de este trabajo producirá un prototipo basado en un circuito Arduino Uno, R3, con un bajo consumo eléctrico y un diseño simple, que puede ser utilizado, tanto en el hogar, como en ambientes comerciales.
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8

Mohammadi, Alireza, Austin Kucharsky, and Nathir A. Rawashdeh. "UVC and far-UVC light disinfection ground robot design for sterilizing the Coronavirus on vertical surfaces." In Autonomous Systems: Sensors, Processing and Security for Ground, Air, Sea and Space Vehicles and Infrastructure 2022, edited by Michael C. Dudzik, Theresa J. Axenson, and Stephen M. Jameson. SPIE, 2022. http://dx.doi.org/10.1117/12.2618558.

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9

"Comparison of UVC Lamp and UVC-light Emitting Diodes for Treating Municipal Wastewater Reverse Osmosis Concentrate." In International Conference on Biological, Civil and Environmental Engineering. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c0314076.

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10

Li, Yiyang, Jianxia Ning, Zhengyuan Xu, Srikanth V. Krishnamurthy, and Gang Chen. "UVOC-MAC: A MAC protocol for outdoor ultraviolet networks." In 2010 18th IEEE International Conference on Network Protocols (ICNP). IEEE, 2010. http://dx.doi.org/10.1109/icnp.2010.5762756.

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Звіти організацій з теми "UvrC"

1

Tawfik, Aly, Deify Law, Juris Grasis, Joseph Oldham, and Moe Salem. COVID-19 Public Transportation Air Circulation and Virus Mitigation Study. Mineta Transportation Institute, June 2022. http://dx.doi.org/10.31979/mti.2021.2036.

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COVID-19 may have forever changed our world. Given the limited space and air circulation, potential infections on public transportation could be concerningly high. Accordingly, this study has two objectives: (1) to understand air circulation patterns inside the cabins of buses; and (2) to test the impact of different technologies in mitigating viruses from the air and on surfaces inside bus cabins. For the first objective, different devices, metrics and experiments (including colored smoke; videotaping; anemometers; pressure differentials; particle counts; and 3D numerical simulation models) were utilized and implemented to understand and quantify air circulation inside different buses, with different characteristics, and under different operating conditions (e.g. with windows open and shut). For the second objective, three different live prokaryotic viruses were utilized: Phi6, MS2 and T7. Various technologies (including positive pressure environment inside the cabin, HEPA filters with different MERV ratings, concentrated UV exposure with charged carbon filters in the HVAC systems, center point photocatalytic oxidation technology, ionization, and surface antiviral agents) were tested to evaluate the potential of mitigating COVID-19 infections via air and surfaces in public transportation. The effectiveness of these technologies on the three live viruses was tested in both the lab and in buses in the field. The results of the first objective experiments indicated the efficiency of HVAC system designs, where the speed of air spread was consistently much faster than the speed of air clearing. Hence, indicating the need for additional virus mitigation from the cabin. Results of the second objective experiments indicated that photocatalytic oxidation inserts and UVC lights were the most efficient in mitigating viruses from the air. On the other hand, positive pressure mitigated all viruses from surfaces; however, copper foil tape and fabrics with a high percentage of copper mitigated only the Phi6 virus from surfaces. High-temperature heating was also found to be highly effective in mitigating the different viruses from the vehicle cabin. Finally, limited exploratory experiments to test possible toxic by-products of photocatalytic oxidation and UVC lights inside the bus cabin did not detect any increase in levels of formaldehyde, ozone, or volatile organic compounds. Implementation of these findings in transit buses, in addition to the use of personal protective equipment, could be significantly valuable for protection of passengers and drivers on public transportation modes, possibly against all forms of air-borne viruses.
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2

Tawfik, Aly, Deify Law, Juris Grasis, Joseph Oldham, and Moe Salem. COVID-19 Public Transportation Air Circulation and Virus Mitigation Study. Mineta Transportation Institute, June 2022. http://dx.doi.org/10.31979/mti.2022.2036.

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Анотація:
COVID-19 may have forever changed our world. Given the limited space and air circulation, potential infections on public transportation could be concerningly high. Accordingly, this study has two objectives: (1) to understand air circulation patterns inside the cabins of buses; and (2) to test the impact of different technologies in mitigating viruses from the air and on surfaces inside bus cabins. For the first objective, different devices, metrics and experiments (including colored smoke; videotaping; anemometers; pressure differentials; particle counts; and 3D numerical simulation models) were utilized and implemented to understand and quantify air circulation inside different buses, with different characteristics, and under different operating conditions (e.g. with windows open and shut). For the second objective, three different live prokaryotic viruses were utilized: Phi6, MS2 and T7. Various technologies (including positive pressure environment inside the cabin, HEPA filters with different MERV ratings, concentrated UV exposure with charged carbon filters in the HVAC systems, center point photocatalytic oxidation technology, ionization, and surface antiviral agents) were tested to evaluate the potential of mitigating COVID-19 infections via air and surfaces in public transportation. The effectiveness of these technologies on the three live viruses was tested in both the lab and in buses in the field. The results of the first objective experiments indicated the efficiency of HVAC system designs, where the speed of air spread was consistently much faster than the speed of air clearing. Hence, indicating the need for additional virus mitigation from the cabin. Results of the second objective experiments indicated that photocatalytic oxidation inserts and UVC lights were the most efficient in mitigating viruses from the air. On the other hand, positive pressure mitigated all viruses from surfaces; however, copper foil tape and fabrics with a high percentage of copper mitigated only the Phi6 virus from surfaces. High-temperature heating was also found to be highly effective in mitigating the different viruses from the vehicle cabin. Finally, limited exploratory experiments to test possible toxic by-products of photocatalytic oxidation and UVC lights inside the bus cabin did not detect any increase in levels of formaldehyde, ozone, or volatile organic compounds. Implementation of these findings in transit buses, in addition to the use of personal protective equipment, could be significantly valuable for protection of passengers and drivers on public transportation modes, possibly against all forms of air-borne viruses.
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3

Mora-Pérez, Dora Alicia, Julio Escobar-Potes, Arley Barandica-Villegas, Diana M. Cortázar-Gómez, Johana Andrea Sanabria-Domínguez, and Cristian Camilo Guevara-Acevedo. Boletín Económico Regional: Suroccidente, IV trimestre de 2022. Banco de la República Colombia, March 2023. http://dx.doi.org/10.32468/ber-surocc.tr4-2022.

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En el cuarto trimestre de 2022, la actividad económica de Suroccidente registró un crecimiento anual; aunque, con menor dinámica respecto a los trimestres previos. Los mejores resultados se observaron en la industria manufacturera y los desembolsos de crédito agropecuario de Finagro para estimular este sector, cuya oferta estuvo afectada nuevamente por la intensidad de las precipitaciones y el alto costo de los insumos. Por el contrario, se evidenciaron reducciones en las ventas reales del comercio interno, incluidas las de vehículos nuevos, el transporte, la construcción de edificaciones y la venta de vivienda nueva; en esta última debido al agotamiento de los subsidios a compradores, y a los mayores costos de financiación, tanto en UVR por la alta inflación, como en tasas por la política monetaria. Finalmente, la tasa de desempleo cerró a la baja en las tres ciudades capitales de la región; mientras que, la inflación fue alta al triplicarse los precios de la canasta de alimentos, seguidos del costo de los servicios públicos y de los combustibles.
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4

Banai, Menachem, and Gary Splitter. Molecular Characterization and Function of Brucella Immunodominant Proteins. United States Department of Agriculture, July 1993. http://dx.doi.org/10.32747/1993.7568100.bard.

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The BARD project was a continuation of a previous BARD funded research project. It was aimed at characterization of the 12kDa immunodominant protein and subsequently the cloning and expression of the gene in E. coli. Additional immunodominant proteins were sought among genomic B. abortus expression library clones using T-lymphocyte proliferation assay as a screening method. The 12kDa protein was identified as the L7/L12 ribosomal protein demonstrating in the first time the role a structural protein may play in the development of the host's immunity against the organism. The gene was cloned from B. abortus (USA) and B. melitensis (Israel) showing identity of the oligonucleotide sequence between the two species. Further subcloning allowed expression of the protein in E. coli. While the native protein was shown to have DTH antigenicity its recombinant analog lacked this activity. In contrast the two proteins elicited lymphocyte proliferation in experimental murine brucellosis. CD4+ cells of the Th1 subset predominantly responded to this protein demonstrating the development of protective immunity (g-IFN, and IL-2) in the host. Similar results were obtained with bovine Brucella primed lymphocytes. UvrA, GroE1 and GroEs were additional Brucella immunodominant proteins that demonstrated MHC class II antigenicity. The role cytotoxic cells are playing in the clearance of brucella cells was shown using knock out mice defective either in their CD4+ or CD8+ cells. CD4+ defective mice were able to clear brucella as fast as did normal mice. In contrast mice which were defective in their CD8+ cells could not clear the organisms effectively proving the importance of this subtype cell line in development of protective immunity. The understanding of the host's immune response and the expansion of the panel of Brucella immunodominant proteins opened new avenues in vaccine design. It is now feasible to selectively use immunodominant proteins either as subunit vaccine to fortify immunity of older animals or as diagnostic reagents for the serological survaillance.
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