Готові списки джерел за темами / TMY

Добірка наукової літератури з теми "TMY"

Автор: Grafiati
Опубліковано: 14 березня 2023

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Статті в журналах з теми "TMY"

1

Rani, Mafia, N. M. A. Hadia, Ahmed M. Shawky, Rana Farhat Mehmood, Shanza Hameed, Saba Zahid, Javed Iqbal, Naifa S. Alatawi, Asma Ahmed та Rasheed Ahmad Khera. "Novel A-π-D-π-A type non-fullerene acceptors of dithienyl diketopyrropopyrrole derivatives to enhance organic photovoltaic applications: a DFT study". RSC Advances 13, № 3 (2023): 1640–58. http://dx.doi.org/10.1039/d2ra07291b.

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Анотація:
The investigated non-fullerene acceptor molecules TM1, TM2, TM3, TM4, TM5, TM6, and TM7 that are fashioned by making alterations at the terminal position of reference molecule TMR demonstrate significant absorption in the visible region.
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2

Leavitt, J., G. Latter, L. Lutomski, D. Goldstein, and S. Burbeck. "Tropomyosin isoform switching in tumorigenic human fibroblasts." Molecular and Cellular Biology 6, no. 7 (July 1986): 2721–26. http://dx.doi.org/10.1128/mcb.6.7.2721-2726.1986.

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Анотація:
We identified six tropomyosin (Tm) isoforms in diploid human fibroblasts. We used computerized microdensitometry of 2-dimensional protein profiles to measure the relative rates of synthesis and abundance of the individual Tm isoforms and actin, the two major structural constituents of microfilaments. In carcinogen-transformed human fibroblasts (HuT-14), the rates of synthesis of three Tm isoforms (Tm1, Tm2, and Tm6) were greatly decreased relative to normal diploid parental fibroblasts and to actin. In contrast, related nontumorigenic HuT fibroblasts which are "immortalized" and anchorage independent exhibited both slight down-regulation of Tm1 and Tm6 and 3.5-fold up-regulation of Tm3. Thus, Tm isoform switching from the predominance of the larger more avid Tm isoforms (Tm1, Tm2, Tm3, and Tm6) to the smaller, less avid Tm isoforms (Tm4 and Tm5) in microfilaments was a transformation-induced change correlated with tumorigenicity in human fibroblasts.
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3

Leavitt, J., G. Latter, L. Lutomski, D. Goldstein, and S. Burbeck. "Tropomyosin isoform switching in tumorigenic human fibroblasts." Molecular and Cellular Biology 6, no. 7 (July 1986): 2721–26. http://dx.doi.org/10.1128/mcb.6.7.2721.

Повний текст джерела
Анотація:
We identified six tropomyosin (Tm) isoforms in diploid human fibroblasts. We used computerized microdensitometry of 2-dimensional protein profiles to measure the relative rates of synthesis and abundance of the individual Tm isoforms and actin, the two major structural constituents of microfilaments. In carcinogen-transformed human fibroblasts (HuT-14), the rates of synthesis of three Tm isoforms (Tm1, Tm2, and Tm6) were greatly decreased relative to normal diploid parental fibroblasts and to actin. In contrast, related nontumorigenic HuT fibroblasts which are "immortalized" and anchorage independent exhibited both slight down-regulation of Tm1 and Tm6 and 3.5-fold up-regulation of Tm3. Thus, Tm isoform switching from the predominance of the larger more avid Tm isoforms (Tm1, Tm2, Tm3, and Tm6) to the smaller, less avid Tm isoforms (Tm4 and Tm5) in microfilaments was a transformation-induced change correlated with tumorigenicity in human fibroblasts.
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4

Nazeer, Khurram, Michael G. Janech, Jim J. C. Lin, Kevin J. Ryan, John M. Arthur, and Milos N. Budisavljevic. "Changes in protein profiles during course of experimental glomerulonephritis." American Journal of Physiology-Renal Physiology 296, no. 1 (January 2009): F186—F193. http://dx.doi.org/10.1152/ajprenal.90222.2008.

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Анотація:
Better characterization of the molecular mechanisms underlying glomerular cell proliferation may improve our understanding of the pathogenesis of glomerulonephritis and yield disease-specific markers. We used two-dimensional gel electrophoresis (2DE) and mass spectrometry (MS) to generate expression profiles of glomerular proteins in the course of anti-Thy-1 nephritis. Glomeruli were isolated from Wistar rats by sieving, and proteins were separated by 2DE. In preliminary studies using normal rats, we identified known glomerular proteins from microfilaments [tropomyosin (Tm)] and intermediate filaments (vimentin and lamin A), proteins involved in assembly (α-actinin-4, F-actin capping protein) and membrane cytoskeletal linking (ezrin), as well as several enzymes (protein disulfide isomerase, ATP synthase, and aldehyde dehydrogenase). Comparison of glomerular protein abundance between normal rats and rats in the early phase of anti-Thy-1 nephritis yielded 28 differentially expressed protein spots. MS analysis identified 16 differentially expressed proteins including Tm. Altered Tm abundance in the course of anti-Thy-1 nephritis was confirmed, and specific isoforms were characterized by Western blotting. We demonstrated a complex change in Tm isoform abundance in the course of anti-Thy-1 nephritis. The early mesangiolytic phase of the disease was characterized by decreased abundance of low-molecular-weight isoforms Tm5a/5b and increased abundance of high-molecular-weight isoforms Tm6, Tm1, Tm2, and Tm3. The late proliferative phase of the disease was associated with increased abundance of isoforms Tm5a/5b, Tm6, and Tm1 and decreased abundance of Tm3. Isoforms Tm4 and Tm5 remained unchanged in the course of this model of experimental glomerulonephritis. Characterization of Tm isoform abundance in the course of clinical glomerulonephritis may identify disease-specific markers.
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5

SALDANHA, DEJANIRA LUDERITZ, MARIA DO CARMO LIMA E. CUNHA DO CARMO LIMA E. CUNHA, and JOSÉ CARUSO MORESCO DANNI. "Identificação de Rochas Ultramáficas por Imagens Digitais TM - Landsat 5 no Escudo Sul-rio-grandense, RS." Pesquisas em Geociências 35, no. 1 (July 1, 2008): 21. http://dx.doi.org/10.22456/1807-9806.17892.

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Анотація:
Principal Components of Landsat TM images were used aiming to identify occurrences of ultramafic rocks in Rio Grande do Sul State, Brazil. Principal Component involving the pairs of bands TM1-TM5, TM4-TM2 and TM5-TM7 showed to be the best for the purposes of the study. Field surveys confirmed the results obtained by digital processing of the images.
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6

Fan, Xinying, Bin Chen, Changfeng Fu, and Lingyun Li. "Research on the Influence of Abrupt Climate Changes on the Analysis of Typical Meteorological Year in China." Energies 13, no. 24 (December 10, 2020): 6531. http://dx.doi.org/10.3390/en13246531.

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Анотація:
The conventional typical meteorological year (TMY) based on continuous-year original meteorological records without considering abrupt climate changes (ACC) may not be able to represent a real “typical” climate properly. Consequently, building performance analyses and simulations based on TMY may be not accurate. Current research rarely tackles this issue in TMY development. This paper presents an innovative TMY development with the consideration of ACC in the original meteorological records. It is based on the Chinese standard weather database method (CSWD) with the meteorological records of six Chinese cities in different climate zones. It applies the Moving t-test method to identify and exclude ACC points and to refine the timescales for TMY development. It also depicts the development of individual typical meteorological months again with the ACC impact to improve the accuracy of TMY. The method has been verified in several building energy consumption and thermal comfort analyses. The results demonstrate that the analysis based on the new TMY climate datasets when considering ACC will end up with less energy consumption and better thermal performance compared to the analyses based on the conversion dataset without considering ACC. This experimental research will refine TMY development, and further improve building energy performance analysis and design.
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7

Zang, Haixiang, Qingshan Xu, Pengwei Du, and Katsuhiro Ichiyanagi. "A Modified Method to Generate Typical Meteorological Years from the Long-Term Weather Database." International Journal of Photoenergy 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/538279.

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Анотація:
A modified typical meteorological year (TMY) method is proposed for generating TMY from practical measured weather data. A total of eleven weather indices and novel assigned weighting factors are applied in the processing of forming the TMY database. TMYs of 35 cities in China are generated based on the latest and accurate measured weather data (dry bulb temperature, relative humidity, wind velocity, atmospheric pressure, and daily global solar radiation) in the period of 1994–2010. The TMY data and typical solar radiation data are also investigated and analyzed in this paper, which are important in the utilizations of solar energy systems.
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8

Zhang, J. T. "Sequence requirements for membrane assembly of polytopic membrane proteins: molecular dissection of the membrane insertion process and topogenesis of the human MDR3 P-glycoprotein." Molecular Biology of the Cell 7, no. 11 (November 1996): 1709–21. http://dx.doi.org/10.1091/mbc.7.11.1709.

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Анотація:
The biogenesis of membrane proteins with a single transmembrane (TM) segment is well understood. However, understanding the biogenesis and membrane assembly of membrane proteins with multiple TM segments is still incomplete because of the complexity and diversity of polytopic membrane proteins. In an attempt to investigate further the biogenesis of polytopic membrane proteins, I used the human MDR3 P-glycoprotein (Pgp) as a model polytopic membrane protein and expressed it in a coupled cell-free translation/translocation system. I showed that the topogenesis of the C-terminal half MDR3 Pgp molecule is different from that of the N-terminal half. This observation is similar to that of the human MDR1 Pgp. The membrane insertion properties of the TM1 and TM2 in the N-terminal half molecule are different. The proper membrane anchorage of both TM1 and TM2 of the MDR3 Pgp is affected by their C-terminal amino acid sequences, whereas only the membrane insertion of the TM1 is dependent on the N-terminal amino acid sequences. The efficient membrane insertion of TM3 and TM5 of MDR3 Pgp, on the other hand, requires the presence of the putative TM4 and TM6, respectively. The TM8 in the C-terminal half does not contain an efficient stop-transfer activity. These observations suggest that the membrane insertion of putative TM segments in the human MDR3 Pgp does not simply follow the prevailing sequential event of the membrane insertion by signal-anchor and stop-transfer sequences. These results, together with my previous findings, suggest that different isoforms of Pgp can be used in comparison as a model system to understand the molecular mechanism of topogenesis of polytopic membrane proteins.
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9

Khalifa, Yosof, and Farag Alargt. "The Generation of Typical Meteorological Year for Tripoli, Libya." Solar Energy and Sustainable Development Journal 7, no. 1 (June 30, 2018): 18–23. http://dx.doi.org/10.51646/jsesd.v7i1.34.

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Анотація:
In this paper a Typical Meteorological Year (TMY) of Tripoli city, the capital of Libya was presented and analyzed using twelve year of measured weather data, this data includes global solar radiation, air temperature and wind speed. Th measurements were taken every ten minutes. Finkelstein–Schafer statistical method was applied to analyze the data and obtain the TMY for the site. Typical Meteorological Months (TMMs) were selected by choosing the one with the least deviation from the long-term cumulativedistribution function. A close-fi agreement is observed between the generated TMY and the long-term averages. Ths TMY generated will be very useful tool for optimal design and performance evaluation of solar energy conversion systems, heating, wind, and other renewable energy systems to be located in this part of Libya.
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10

Grudzińska, Magdalena, and Ewa Jakusik. "Energy performance of buildings in Poland on the basis of different climatic data." Indoor and Built Environment 26, no. 4 (February 9, 2016): 551–66. http://dx.doi.org/10.1177/1420326x16631031.

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Анотація:
Typical Meteorological Years (TMY) were prepared in Poland due to the introduction of obligatory energy certification for buildings. They are based on source data collected by the Institute of Meteorology and Water Management from 1971 to 2000. Predictions indicate that until the end of the 21st century, the air temperature will increase. Therefore, the characteristics obtained with the use of TMY may differ from the energy demand of buildings used nowadays. This article compares energy demand calculated with the use of TMY and subsequent climatic data from 2001 to 2012, for three different locations in Poland. The analyses were performed with the use of the dynamic simulation computer program, for typical living quarters in a multifamily residential building with different construction and window orientation. Results obtained with the use of TMY and subsequent climatic data show that the typical years can be used for the evaluation of heating demand. However, cooling demand calculated with the use of TMY was significantly lower in comparison with the mean cooling demand for the years 2001–2012. This may distort the energy needs and indoor environment conditions in summer, and cause discomfort or unnecessary energy use in presently occupied dwellings.
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Більше джерел

Дисертації з теми "TMY"

1

Lukášová, Veronika. "Posvítit si do tmy." Doctoral thesis, Vysoké učení technické v Brně. Fakulta výtvarných umění, 2019. http://www.nusl.cz/ntk/nusl-403863.

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Анотація:
My disertation theses explores the intricate relationship between art, science and photography in the framework of the contemporary culture. Clearly outlined research areas open up the subject to a broader theoretical examination to underpin the artistic strategies that can be employed in the practial research. The resulting artwork interprets the domain of particle physics in a series of artworks. First area of the research delves into the domain of images and seeks to understand the relationship between the images of art and science in a broader sense. Second area investigates ambiguous medium of photography as both tool of science and art. Third area is an overview of the history of representation of the subatomic world and issues related to representing what is in fact unrepresentable. Fourth seeks to find epistemic and conceptual connection between art and science and their interdisciplinary dialogue as Sci-Art. The fifth part introduces artworks that reflect the critical egangement with the theoretical research and the scientific method by building the instrument for the observation of the cosmic rays. Sources for the theoretical framework are largely drawn from the academic literature written in the UK and USA where the topics explored in the theses have been studied in depth. The time scope considered in the theses encompasses 1990's of the 20. century up utill the present day.
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2

Demirocak, Emre Dervis. "Thermodynamic And Economic Analysis Of A Solar Thermal Powered Adsorption Cooling System." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12610110/index.pdf.

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Анотація:
In this thesis, yearly performance of the solar adsorption cooling system which is proposed to be installed to a residential building in Antalya is theoretically investigated in detail. Firstly, thermodynamic designs of the adsorption cooling cycle for three different types of cycles which are intermittent, heat recovery and heat &
mass recovery cycles are presented. Secondly, adsorption characteristics of three adsorbent/adsorbate pairs which are zeolite-water, silica gel-water and activated carbon-methanol are given. Following this, load side (i.e., building) of the system is designed and parameters that should be considered in building design are presented. Then, solar-thermal cooling system design methodology with an emphasis on solar fraction is presented. In addition, system parameters effecting the performance of the adsorption cooling system are analyzed and results are presented. Finally, economic analysis is done in order to understand the economic feasibility of the solar-thermal cooling systems compared to conventional cooling systems. TRNSYS is used for the yearly simulations and an integrated model of the overall system is developed in TRNSYS. Since energy consumption and performance investigations of environment-dependent systems such as building HVAC, refrigeration systems and solar collectors usually require weather information, typical meteorological year (TMY) data for Antalya is also generated in order to be used in the analysis of the system parameters.
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3

Yang, X. (Xiaojiang). "Magnetic resonance imaging of the lateral pterygoid muscle in temporomandibular disorders." Doctoral thesis, University of Oulu, 2002. http://urn.fi/urn:isbn:9514266439.

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Анотація:
Abstract The fact that the lateral pterygoid muscle (LPM) and related symptoms play an important role in temporomandibular disorders (TMD) is widely recognized. In the study reported here, the LPM was investigated by magnetic resonance imaging (MRI) of patients with TMD. The visibility of the LPM in MRI with different projections was analyzed and a new imaging projection, condyle-the lateral pterygoid muscle projection (CLPM), for the LPM in MRI was introduced. Normal and abnormal findings of the LPM was compared with clinical symptoms of TMD. Compared with sagittal imaging of temporomandibular joint (TMJ), CLPM images and most of the oblique sagittal imaging were able to show the LPM clearly. Hypertrophy, atrophy and contracture of the LPM were found in TMJs either with disc in normal position or with disc displacements. Pathological changes of the superior belly and hypertrophy of the inferior belly combined with various pathological changes of the superior belly were the most frequently observed abnormal imaging findings of the LPM in TMD. The pathological changes of the LPM were associated with the main clinical symptoms of TMD. In patients with symptomatic condyle hypermobility, the pathological changes of the LPM and related symptoms were associated with the clinical symptoms of TMJs with disc in normal position. The imaging abnormalities of the LPM were common in TMJs with disc displacements and seemed to be fewer in condyle hypomobility cases in TMJs with anterior disc displacement with non-reduction (ADDnr). However, normal imaging of the LPM was also found in TMJs with severe osteoarthritic changes and disc displacement. The recognition of muscle alterations may lead to a more specific diagnosis and improve the understanding of the clinical symptoms and disease pathophysiology of TMD.
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4

Edwards, Emery Rose. "Illness Experience of People with Chronic Pain Resulting from Temporomandibular Disorders." Thesis, The University of Arizona, 2007. http://hdl.handle.net/10150/193257.

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Анотація:
This thesis discusses the illness experience of people living with chronic pain resulting from Temporomandibular disorders (TMD). The literature discusses various aspects of the experience of chronic pain, but there is little research reported specifically on the experience of living with TMD. Using analysis of sufferers' narratives, I discuss common explanatory models and coping strategies. I then present aspects of the bodily experience of TMD as seen in people with comorbid illnesses. The personal or mental aspects of TMD are explored, particularly in terms of fear, anxiety, and hope for the future. Lastly, the broader impacts of TMD are explored through sufferers' relationships with friends and family, and sufferers' ability to function in social contexts. It is concluded that TMD impacts many areas of sufferers' lives, and that the lived experience extends beyond diagnosis and treatment seeking to include the day to day management of TMD pain.
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5

Jára, Jaroslav. "Návrh postupu při obnově napájení vlastní spotřeby zdrojů Tepláren Brno po rozsáhlé systémové poruše v ES." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2015. http://www.nusl.cz/ntk/nusl-220373.

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Анотація:
This work deals with the issue of supply restoring for heating plant Teplárny Brno, a. s. Špitálka division, after a system-wide failure of the “blackout”. The thesis solves the “black start” of the Špitálka Teplárny Brno operation by delivering a voltage from the hydroelectric power Vír I, proposes a methodology for commissioning of individual devices, up to phasing the generators with subsequent possibility of creating an “island mode” in the area of Brno city, which the work already does not deal with. The work also deals with the preparation of the operational test, while starts of the selected devices are tested. The schedule of commissioning of each device is supported by calculations of the parameters for the entire system with regard to voltage drops while connecting the high load. The result of this work is the proposal of methodological process of supply restoring for power plant Teplárny Brno – Špitálka division, by submission a voltage from the hydroelectric power Vír I, which can be used both in any system-wide failure of the “blackout”, or during the operational test.
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6

Alder, Emma K. "Temporomandibular Joint Disorder: An Investigation of Masseter Muscle Activity in Response to Stressful Computer Data Entry." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1339772763.

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7

Harris, Darren Samuel. "Traffic management alternatives for business improvement districts." Thesis, Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/52255.

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Анотація:
When a vehicle enters an intersection with insufficient space to exit on the opposite side the result is often the obstruction of pedestrians and other vehicles, this phenomenon is usually referred to as "blocking the box." The purpose of this study was to determine different characteristics of blocking that might be considered in determining the installment of a "Don't Block the Box" (DBTB) campaign. This study identified potentially problematic intersections in Atlanta, Georgia and collected information, such as the number of vehicles that block the intersection (box junction), the amount of green time with blocking, and the percentages in which approaches were blocked. Based on the results it was found the characteristics of the number of blockers, percentage of green time with blocking, and the percentage of lost capacity are excellent indicators for a possible DBTB campaign. Organizations interested in potentially starting a DBTB should consider these characteristics part of the determination of suitability of DBTB for an intersection. Within this study is was found that the intersections of Peachtree Road & Highland Drive, Peachtree Road & Stratford Road, Peachtree Road & Lenox Mall Entrance, and 10th Street & Williams Street showed to be potential candidates for a DBTB campaign in Atlanta, Georgia. During the study period these intersections had high percentages of lost capacity, high number of blocks, and high percentages of green time with blocking. In conjunction with the DBTB data analysis a "DBTB survey" was developed. The objective of this survey was to help gain a better understanding of the current trends in DBTB campaigns around the United States. The "DBTB Survey" received 75 responses from 415 organizations around the nation, a 18.1% response rate. Six (60%) of the ten participants that currently have a DBTB campaign found a sufficient level of improvement in traffic operations and 46 of the total respondents (60%) proclaimed that if DBTB campaigns were shown to be an economical alternative for traffic management they would consider starting one to help congestion and safety.
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8

Silva, Álvaro Múcio Leite da [UNESP]. "Análise da intensidade e frequências dos ruídos articulares da articulação temporomandibular." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/97068.

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Анотація:
Made available in DSpace on 2014-06-11T19:28:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-12-12Bitstream added on 2014-06-13T18:57:54Z : No. of bitstreams: 1 silva_aml_me_guara.pdf: 1372198 bytes, checksum: 8bdab5df0828cfa6c6b83983a359c40b (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O presente trabalho tem por objetivos, analisar a intensidade e freqüência dos ruídos articulares da articulação temporomandibular (A.T.M.) de indivíduos saudáveis e patológicos, auxiliar nos procedimentos clínicos e em futuras pesquisas. Para a análise dos sinais coletados foi desenvolvido um sistema para aquisição de dados, composto por um conjunto estetoscópio/microfone, equipamentos para condicionamento e aquisição de sinais e aplicativos computacionais para registro, análise e apresentação dos dados. A identificação das freqüências dominantes e o cálculo dos parâmetros considerados no domínio do tempo (valor médio, valor eficaz, desvio padrão e nível da pressão sonora – NPS) foram realizados por meio de programas computacionais específicos. Os resultados decorrentes dos cálculos e das observações em relação aos sinais obtidos, possibilitaram a determinação das faixas de freqüência, o nível da pressão sonora em decibéis (dB)* da população em estudo, além de proporcionar algumas diferenças entre os grupos patológicos e não-patológicos. Pode-se concluir que a presença da patologia influiu na amplitude dos sinais coletados, diferenciando dessa forma os casos patológicos dos não patológicos. Outra contribuição desse trabalho foi o desenvolvimento de um exame não invasivo para as Disfunções das Articulações Temporomandibulares (D.T.Ms.)
This word has the objective of analyzing the amount and frequency of articular noise in temporomandibular joint (TMJ) of both healthy and pathological individuals and aid in clinical procedures as well as in future researches. For the proposed analysis, a dada collecting system was developed comprising a stethoscope/microphone set, equipment for the signal conditioning and capturing, and computer software for data recording, analysis and presentation. The identification of dominating frequencies and the parameter calculation considered in the time period (average amount, efficient amount, linear fit, and sound pressure level) were performed through specific computer softwares. The results found through the calculations and observations in relation to the signals obtained made the determination of the frequency, the level of sound pressure (in dB) of the studied population possible besides differentiating the pathological and non-pathological groups. It can be concluded that the presence of the pathology influenced in the amplitude of the collected signals, differentiating of this form the pathological cases of the not pathological ones. Another contribution of this work was the development of a not invasive examination for the temporomandibular dysfunction (TMD)
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9

Foley, Bryan Francis. "IDENTIFICATION OF POTENTIAL GENETIC MARKERS OF FACIAL ASYMMETRY AND TMD IN ORTHOGNATHIC SURGERY PATIENTS." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/286577.

Повний текст джерела
Анотація:
Oral Biology
M.S.
Temporomandibular disorders (TMD) are comorbid conditions. Most are related to anxiety-induced muscular pain, but some are associated with facial asymmetry resulting from condylar resorption (CR) or condylar hyperplasia (CH). The etiology of the most common forms of CH and CR are still unknown. CR can be caused by rheumatoid arthritis (RA) or more commonly osteoarthritis (OA) of the TMJ, and inflammatory mediators have been previously implicated. Previous studies have identified pain/inflammatory genes related to chronic TMD while others have demonstrated potential genetic markers for RA. Similarly, genome-wide association (GWA) studies have identified genes associated with height, some of which may participate in craniofacial growth, CH, and the development of asymmetry. Masseter muscle is frequently involved in TMD of muscular origin, and left/right fiber-type differences have been previously found in subjects with facial asymmetry. A human transcriptome microarray was used to evaluate whether genes involved with height, pain, or inflammation were differentially expressed in masseter muscle from facially asymmetric patients with and without TMD. This study evaluated orthognathic surgery patients with varying skeletal malocclusions, including subjects with and without facial asymmetry and TMD (n= 93). Masseter muscle samples were collected from ten orthognathic surgery patients treated to correct skeletal malocclusions. Two of whom were classified with facial asymmetry with or without TMD, with one of the two showing positive evidence of CR. Samples were disrupted in QIAzol Lysis Reagent, RNA was isolated using a Qiagen miRNeasy Mini Kit according to the manufacturer's instructions, and quality of the total RNA was tested by Agilent Bioanalyzer and Nanodrop spectrophotometry. Samples were used for quantitative Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) and protocols for microarray analysis were conducted as described in the Ambion WT Expression Manual and the Affymetrix GeneChip Expression Analysis Technical Manual. Principal Components Analysis (PCA) was completed to detect fold-changes for each transcript to determine differences in global gene expression between the two asymmetric and eight remaining subjects. To find differentially expressed transcripts step-up t-tests were performed to correct for false discovery rate (FDR) comparing the two asymmetric samples to the eight symmetric samples. Differences were considered significant if step-up p-values were ±2 between groups. This study evaluated 847 height-related genes and 551 genes associated in pain/inflammatory processes. Genes of interest were determined a priori from GWA studies and the Algynomics Pain Research Panel v.2.0 partially derived from the Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) study. Two hundred and eight transcripts of 847 height associated genes and 132 of 551 pain/inflammatory genes were significant for expression (P±2.0 fold differences in facial asymmetry and/or TMD specimens. Among genes specifically reported to be associated with pain/inflammation, NPY5R (+2.11 fold), GABRA6 (+2.14 fold), CACNA2D1 (-12.51 fold) and EREG (+2.12 fold) showed significantly different (P<0.001) expression levels in the two asymmetric versus the remaining eight symmetric patients. CACNA2D1 expression was significantly increased in symmetric male subjects versus symmetric females (P < 0.05) as well as in asymmetric females versus asymmetric males (P < 0.05). CACNA2D1 expression was also significantly increased in symmetric male subjects versus symmetric females (P <0.05) and was differentially expressed at lower levels, however not significantly, in asymmetric males (p = 0.51). Based on the results collected, the following conclusions were drawn. These methods provide a novel approach to study TMD and/or facial asymmetry in human subjects. To our knowledge, this is the first study to demonstrate that significant expression variation in human height genes may contribute to facial asymmetry with or without TMD, possibly through decreased expression of CACNA2D1. These data suggest TMD patients with facial asymmetry associated with condylar resorption may show significant differential expression of certain inflammatory marker genes such as EREG and CACNA2D1. These data support that gender may play a key role in the development of TMD, possibly through increased CACNA2D1 expression providing protective effects in TMD-free males but deleterious effect in females with TMD. These results support previous findings of pain/inflammatory genes associated with TMD derived from muscular pain. Further studies are needed to understand the genetic contributions to TMD, which may play an important role in future clinical intervention.
Temple University--Theses
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10

Bauerle, Erin Ruane. "ASSOCIATION OF MASSETER MUSCLE CACNA2D1, CACNA1S, GABARAP, AND TRPM7 GENE EXPRESSION IN TEMPOROMANDIBULAR JOINT DISORDERS." Master's thesis, Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/392863.

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Анотація:
Oral Biology
M.S.
A major physiological risk factor of temporomandibular disorders (TMD) is sensitization of peripheral and central nervous system pain processing pathways. Calcium channel, voltage-dependent, alpha-2/delta subunit-1 (CACNA2D1) has a crucial role in relaying nociceptive information in the spinal dorsal horn. Up-regulation of CACNA2D1 results in abnormal excitatory synapse formation and enhanced presynaptic excitatory neurotransmitter release. Blocking CACNA2D1 with gabapentinoid-class drugs relieves orofacial hypersensitivity. Drs. Foley, Horton, and Sciote previously reported that in a small sample group (n=12), CACNA2D1 expression was greater in males than females, but increased in women with TMD. The objectives of this study are to corroborate these data and investigate expression patterns of other ion channel and conducting system genes. Additionally, since the null polymorphism ACTN3-577XX associates with muscle fiber microdamage during eccentric contraction, we tested for possible gene associations with ACTN3-R577XX genotypes. Masseter muscle samples came from human subjects (n=23 male; 48 female) with malocclusions undergoing orthognathic surgery. This population had skeletal disharmony of the jaws and thus was prone to eccentric contraction. Three males and eighteen females were diagnosed with localized masticatory myalgia. Muscle total RNA was isolated and CACNA2D1, CACNA1S, GABARAP, and TRPM7 expression was quantified using RT-PCR. Expression of these genes were compared based on TMD status and various characteristics that may influence TMD including: sex, age, facial symmetry, sagittal dimension, vertical dimension, ACTN3-577 genotype and fiber type. CACNA2D1 expression differed significantly between sexes, overall (p<0.02), and without TMD (p=0.001). Women with (n=13) and without (n=23) TMD differed significantly (p<0.03). CACNA2D1 expression was also significantly higher (p=0.031) in subjects below age 25. Similarly, GABARAP expression was significantly higher (p=0.001) for patients younger than 25 and for patients less than or equal to age 18 (p=0.013). Otherwise, CACNA1S, TRPM7 and GABARAP differences were not significant. GABARAP expression differed, but not significantly by sex and for the ACTN3-577XX-null genotype. In a population of malocclusion patients, masseter muscle CACNA2D1 expression is significantly higher than CACNA1S, TRPM7, and GABARAP. CACNA2D1 expression is greater in males than females without TMD. However, CACNA2D1 expression increases significantly in females with TMD-associated myalgia. This may support evidence for calcium channel regulation of nociception differences seen between sexes in TMD. It was also found that expression of CACNA2D1 and GABARAP is significantly higher in younger subjects. Additionally, observations presented here suggest potential influence of ACTN3-null condition on function of GABARAP.
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Книги з теми "TMY"

1

Borský, Karel. Procitání do tmy. Třebíč: Akcent, 2000.

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Přikryl, Vladimír. Za vlády tmy. Praha: Naše vojsko, 1993.

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Divadla svítící do tmy. Praha: Národní informační a poradenské středisko pro kulturu, 2006.

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Pliešovský, Richard. 3 kroky do tmy. Martin: Ruper, 2000.

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5

Schmögnerová, Brigita. Svetlo sa rodí za tmy. Bratislava: Odkaz, 1998.

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Staženi z k°uže ze tmy vycházíme. Praha: Torst, 2007.

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Tíseň tmy, aneb, Halasovské interpretace po roce 1948. Praha: Akropolis, 2005.

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Sucháň, Ján. Z tmy na svetlo: 53 príhovorov z rádia Twist. Bratislava: Vydavatel̓stvo Ps mont, 1997.

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Žáček, Jan. A oddělil světlo od tmy: Román o Janu Sarkandrovi. Olomouc: Nakl. Velehrad, 1995.

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10

1956-, Križka Teodor, ed. Z tmy svieti tvoja dlaň: Výber z mladšej slovenskej l̕úbostnej poézie. Bratislava: Smena, 1986.

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Частини книг з теми "TMY"

1

Pompeu-Santos, Silvino. "The TISB, TMG and TMF concepts." In Innovation in TBM Traffic Tunnels, 101–32. London: CRC Press, 2023. http://dx.doi.org/10.1201/9781003144861-6.

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2

Turiault, Marc, Caroline Cohen, Guy Griebel, David E. Nichols, Britta Hahn, Gary Remington, Ronald F. Mucha, et al. "TMS." In Encyclopedia of Psychopharmacology, 1324. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4602.

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Weik, Martin H. "try." In Computer Science and Communications Dictionary, 1843. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_20194.

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Ellis, Stephanie. "“Try”." In Five Minutes a Day to an Upgraded Therapy Practice, 69–70. New York: Routledge, 2021. http://dx.doi.org/10.4324/9781003125082-33.

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Abegunde, Maria Hamilton. "Tey." In ASHÉ, 59–73. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003046011-5.

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Raj, Satish R., S. R. Wayne Chen, Robert S. Sheldon, Arti N. Shah, Bharat K. Kantharia, Ulrich Salzer, Bodo Grimbacher, et al. "TMD." In Encyclopedia of Molecular Mechanisms of Disease, 2082. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7008.

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Kallioniemi, Elisa, Mervi Könönen, and Sara Määttä. "TMS-EEG." In Biomedical Engineering Challenges, 175–97. Chichester, UK: John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119296034.ch9.

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Selinger, Jonathan V. "Toy Model." In Introduction to the Theory of Soft Matter, 1–5. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21054-4_1.

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Kouraklis, John. "TMS Aurelius." In Introducing Delphi ORM, 19–68. Berkeley, CA: Apress, 2019. http://dx.doi.org/10.1007/978-1-4842-5013-6_2.

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Hung, Patrick C. K., Laura Rafferty, and Marcelo Fantinato. "Toy Computing." In Encyclopedia of Computer Graphics and Games, 1–3. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-08234-9_197-1.

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Тези доповідей конференцій з теми "TMY"

1

Ferreira, Camila Carvalho, and Henor Artur de Souza. "UTILIZAÇÃO DE ARQUIVOS CLIMÁTICOS PARA A ANÁLISE DAS CONDIÇÕES DE CONFORTO TÉRMICO ADAPTATIVO EM VIÇOSA." In XVIII ENCONTRO NACIONAL DE TECNOLOGIA DO AMBIENTE CONSTRUÍDO. UFRGS, 2020. http://dx.doi.org/10.46421/entac.v18i.812.

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Os índices de conforto térmico são instrumentos para a análise da sensação térmica do usuário e, no caso dos modelos de conforto adaptativo, se baseiam em dados climáticos para a definição da temperatura de conforto e respectivas faixas de conforto térmico. Desta forma, a qualidade do dado climático tem impacto na definição das condições de conforto. Assim, o objetivo deste artigo é avaliar o impacto de diferentes bases de dados climáticos na definição das condições de conforto térmico adaptativo para a cidade de Viçosa. Para tal análise, foram gerados dados horários para um dia típico de cada mês a partir dos dados mensais de temperatura e aplicadas as condições de conforto com base no modelo adaptativo da ASHRAE 55. As condições de conforto geradas a partir dos dados climáticos das Normais Climatológicas e dos arquivos climáticos TMY, TMY2 e TMY3 foram analisadas e comparados. Os resultados apontam que o arquivo no formato TMY tem aplicabilidade limitada, enquanto o formato TMY3 apresenta melhores resultados e mais próximos às condições de conforto estabelecidas a partir das Normais Climatológicas. (Pesquisa de pos doc em andamento)
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2

Mikofski, Mark A., and Rounak Kharait. "Comparison of Predicted PV System Performance with SURFRAD versus TMY." In 2021 IEEE 48th Photovoltaic Specialists Conference (PVSC). IEEE, 2021. http://dx.doi.org/10.1109/pvsc43889.2021.9519024.

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Crawley, Drury, and Linda Lawrie. "Rethinking the TMY: is the ‘Typical’ Meteorological Year Best for Building Performance Simulation?" In 2015 Building Simulation Conference. IBPSA, 2015. http://dx.doi.org/10.26868/25222708.2015.2707.

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Alargt, Farag S., Yosof M. Khalifa, and Ahmad H. Kharaz. "Generation of a TMY for Tripoli City Using the Finkelstein –Schafer Statistical Method." In IECON 2021 - 47th Annual Conference of the IEEE Industrial Electronics Society. IEEE, 2021. http://dx.doi.org/10.1109/iecon48115.2021.9589177.

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5

Gilbert, Robert B., and Kelly Kissock. "The Effect of Thermal Mass on Thermal Transmission Loads." In ASME 2007 Energy Sustainability Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/es2007-36101.

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A finite-difference model is used to simulate the effects of thermal mass on thermal load. A sinusoidal function is used to simulate the exterior air temperature. The interior air temperature set point remains constant. The mechanism by which thermal mass affects thermal load is described. Equations are given to calculate thermal load as a function of the exterior air temperature amplitude, the temperature above and below the mean temperature. Equations are given to calculate the minimum thermal load resulting from thermal mass and therefore the maximum thermal load reduction with thermal mass. Equations and methods are given to calculate the minimum thermal load resulting from thermal mass from weather data files, TMY or TMY2 files. A design equation is given as a guideline to determine the amount of thermal mass required to reduce the thermal load with given weather conditions.
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6

Varadarajan, Krupasagar, and Mario A. Medina. "Estimation of Hourly Solar Loads on the Surfaces of Moving Refrigerated Tractor Trailers Outfitted With Phase Change Materials (PCMs) for Several Routes Across the Continental U.S." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-85476.

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The primary objective of this paper was to calculate solar loads and wind chill temperatures on the surfaces of moving refrigerated tractor trailers outfitted with phase change materials (PCMs) for several routes across the Continental United States. As food transportation vehicles, these trucks experience different environmental conditions as they are in motion. The study of PCMs on food transportation vehicles could lead to new findings related to energy conservation. In this research work, a solar model was developed based on synthesized weather data files obtained from the National Solar Radiation Data Base (NSRDB), which contains weather information from 1961 through 1990 for 239 locations (TMY2 data) and weather information from 1991 through 2005 for 1020 locations (TMY3 data). The solar model comprised two parts, data extraction and solar load calculations. The data extraction part separated and picked out the required fields from the TMY data and used them in the solar load calculations program, which was used to estimate the solar loads and wind chill temperatures of every exposed surface of a moving tractor trailer. These solar loads, and wind chill temperatures would then be used in selecting the adequate type of PCMs for a particular route and time of year. In conventional cargo trucks, the refrigeration units are operated by burning fossil fuels, mainly diesel. Therefore, a decrease in refrigeration load would have an impact in fuel consumption and/or in the reduction in size of the refrigeration equipment’s.
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7

GEORGIOU, George, Mahroo EFTEKHARI, Monjur MOURSHED, and Philip EAMES. "A Study Of The Effect Of Weighting Indices For The Development Of Tmy Used For Building Simulation." In 2017 Building Simulation Conference. IBPSA, 2013. http://dx.doi.org/10.26868/25222708.2013.2241.

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8

Bracht, Matheus Körbes, Vanessa Aparecida Caieiro da Costa, Ana Paula Melo, and Roberto Lamberts. "Série histórica versus ano meteorológico típico: Desempenho térmico de modelo unifamiliar com três alternativas de envoltória em Brasília." In XIX ENCONTRO NACIONAL DE TECNOLOGIA DO AMBIENTE CONSTRUÍDO. UFRGS, 2022. http://dx.doi.org/10.46421/entac.v19i1.1992.

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O trabalho consiste na simulação do desempenho térmico de uma edificação, considerando uma série histórica de Brasília em comparação a um arquivo de ano meteorológico típico (TMY) e o arquivo climático INMET utilizado na NBR15575. Esses arquivos são usados como dados de entrada para simulações termo energéticas de uma edificação unifamiliar com três diferentes envoltórias. Foi possível observar o aumento de temperaturas durante a série histórica, assim como o aumento de carga térmica de resfriamento e temperaturas operativas máximas em todos os casos. Notou-se uma divergência significativa entre os resultados encontrados da série histórica com os do arquivo climático INMET.
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9

Sheline, Carolyn, and Amos Winter. "Machine Learning Method for Forecasting Weather Needed For Crop Water Demand Estimations in Low-Resource Settings Using A Case Study in Morocco." In ASME 2021 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/detc2021-70571.

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Abstract Low and middle income countries often do not have the infrastructure needed to support weather forecasting models, which are computationally expensive and often require detailed inputs from local weather stations. Local, low-cost weather prediction services are needed to enable optimal irrigation scheduling and increase crop productivity for rural farmers in low-resource settings. This work proposes a machine learning approach to predict the weather inputs needed to calculate crop water demand, namely evapotranspiration and precipitation. The focus of this work is on the accuracy with which Moroccan weather can be predicted with a vector autoregression (VAR) model compared to using typical meteorological year (TMY) weather, and how this accuracy changes as the number of weather parameters is reduced.
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10

Chaker, Mustapha, and Cyrus B. Meher-Homji. "Selection of Climatic Design Points for Gas Turbine Power Augmentation." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-46463.

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There is a widespread interest in the application of gas turbine power augmentation technologies such as evaporative cooling or mechanical chilling in the mechanical drive and power generation markets. Very often, the selection of the design point is based on the use of ASHRAE data or a design point that is in the basis of design for the project. This approach can be detrimental and can result in a non optimal solution. In order to evaluate the benefits of power augmentation, users can use locally collected weather data, or recorded hourly bin data set from databases such as TMY, EWD, and IWS. This paper will cover a suggested approach for the analysis of climatic data for power augmentation applications and show how the selection of the design point can impact performance and economics of the installation. The final selection of the design point depends on the specific application, the revenues generated and installation costs. To the authors’ knowledge, this is the first attempt to treat this topic in a structured analytical manner by comparing available database information with actual climatic conditions.
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Звіти організацій з теми "TMY"

1

Habte, A., A. Lopez, M. Sengupta, and S. Wilcox. Temporal and Spatial Comparison of Gridded TMY, TDY, and TGY Data Sets. Office of Scientific and Technical Information (OSTI), February 2014. http://dx.doi.org/10.2172/1126297.

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2

Muñoz, Mario, Philip Brabyn, Manuel Fernandez, and Ian Zylberberg. TMJ Arthrocentesis. Touch Surgery Simulations, 2018. http://dx.doi.org/10.18556/touchsurgery/2018.s0113.

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3

Schnitzler, B. G., and J. B. Briggs. TMI-2 isotopic inventory calculations. Office of Scientific and Technical Information (OSTI), August 1985. http://dx.doi.org/10.2172/6332535.

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Moon, S. TMS XTRRA experiments on NIF. Office of Scientific and Technical Information (OSTI), August 2020. http://dx.doi.org/10.2172/1650443.

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5

McCormick, R. D., J. L. Anderson, and D. W. Golden. TMI-2 data summary report. Office of Scientific and Technical Information (OSTI), September 1987. http://dx.doi.org/10.2172/6120550.

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Gordey, S. P. Geology, central Tay River, Yukon. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2013. http://dx.doi.org/10.4095/288983.

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Wentz, Frank. Updates to TMI Ocean Products. Remote Sensing Systems, March 2015. http://dx.doi.org/10.56236/rss-az.

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Jackson, L. E. Terrain Inventory, Tay River, Yukon Territory. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1986. http://dx.doi.org/10.4095/130179.

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Ruhl, R. C., M. A. Petrik, and T. L. Cable. Status of the TMI SOFC system. Office of Scientific and Technical Information (OSTI), December 1996. http://dx.doi.org/10.2172/460196.

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10

Clower, C. A. Jr. Titanium-getter testing for TMX-U. Office of Scientific and Technical Information (OSTI), March 1985. http://dx.doi.org/10.2172/5883073.

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