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Статті в журналах з теми "RNA pathogenesis"
Chatterjee, Biswanath, Che-Kun James Shen, and Pritha Majumder. "RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis." International Journal of Molecular Sciences 22, no. 21 (November 1, 2021): 11870. http://dx.doi.org/10.3390/ijms222111870.
Повний текст джерелаKarst, Stephanie M. "Pathogenesis of Noroviruses, Emerging RNA Viruses." Viruses 2, no. 3 (March 23, 2010): 748–81. http://dx.doi.org/10.3390/v2030748.
Повний текст джерелаBaysal, Bora E., Shraddha Sharma, Seyedsasan Hashemikhabir, and Sarath Chandra Janga. "RNA Editing in Pathogenesis of Cancer." Cancer Research 77, no. 14 (June 30, 2017): 3733–39. http://dx.doi.org/10.1158/0008-5472.can-17-0520.
Повний текст джерелаDay, John W., and Laura P. W. Ranum. "RNA pathogenesis of the myotonic dystrophies." Neuromuscular Disorders 15, no. 1 (January 2005): 5–16. http://dx.doi.org/10.1016/j.nmd.2004.09.012.
Повний текст джерелаPekarsky, Yuri, and Carlo M. Croce. "Noncoding RNA genes in cancer pathogenesis." Advances in Biological Regulation 71 (January 2019): 219–23. http://dx.doi.org/10.1016/j.jbior.2018.12.002.
Повний текст джерелаPoltronieri, Palmiro, Binlian Sun, and Massimo Mallardo. "RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load." Current Genomics 16, no. 5 (July 10, 2015): 327–35. http://dx.doi.org/10.2174/1389202916666150707160613.
Повний текст джерелаRomano, Giulia, Michela Saviana, Patricia Le, Howard Li, Lavender Micalo, Giovanni Nigita, Mario Acunzo, and Patrick Nana-Sinkam. "Non-Coding RNA Editing in Cancer Pathogenesis." Cancers 12, no. 7 (July 8, 2020): 1845. http://dx.doi.org/10.3390/cancers12071845.
Повний текст джерелаGipson, Theresa A., Andreas Neueder, Nancy S. Wexler, Gillian P. Bates, and David Housman. "Aberrantly splicedHTT,a new player in Huntington’s disease pathogenesis." RNA Biology 10, no. 11 (November 2013): 1647–52. http://dx.doi.org/10.4161/rna.26706.
Повний текст джерелаRanum, Laura P. W., and John W. Day. "Myotonic Dystrophy: RNA Pathogenesis Comes into Focus." American Journal of Human Genetics 74, no. 5 (May 2004): 793–804. http://dx.doi.org/10.1086/383590.
Повний текст джерелаHu, Wen-Yuan, Christopher P. Myers, Jennifer M. Kilzer, Samuel L. Pfaff, and Frederic D. Bushman. "Inhibition of Retroviral Pathogenesis by RNA Interference." Current Biology 12, no. 15 (August 2002): 1301–11. http://dx.doi.org/10.1016/s0960-9822(02)00975-2.
Повний текст джерелаДисертації з теми "RNA pathogenesis"
Frederick, Madeline Rose. "The role of RNA-editing in viral mediated pathogenesis." Kent State University Honors College / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors152545654349718.
Повний текст джерелаAlsomali, Khayria. "Investigating RNA editing in the pathogenesis of amyotrophic lateral sclerosis." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/9182/.
Повний текст джерелаTalbot, Kevin. "The molecular pathogenesis of autosomal recessive spinal muscular atrophy." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300137.
Повний текст джерелаFris, Elizabeth Megan. "Small RNA Sibling Pairs RyfA and RyfB in Shigella dysenteriae and their Impact on Pathogenesis." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1531480621100282.
Повний текст джерелаFahl, Willian de Oliveira. "Marcadores moleculares para a patogenia de vírus da raiva: relação entre períodos de incubação, carga viral e os genes codificadores das proteínas virais P e L." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-24072014-103209/.
Повний текст джерелаRabies is an acute, progressive and infectious disease of the central nervous system of mammals, caused by Rabies virus (RABV). Although preventable by vaccine, it remains a serious public health problem, and is responsible for the death of humans and many other animals, including those of economic interest. This study aimed to assess the relationship between polymorphisms in genes encoding the P and L proteins of RABV samples belonging to antigenic variants 2 and 3 and incubation periods and titers in mice. For this, samples isolated from different mammalian rabies reservoirs of the Orders Carnivora and Chiroptera and samples of cattle from endemic areas for rabies virus were selected. The sequences obtained were used to construct phylogenetic trees to search for the segregation patterns of strains. The results showed that there were no markers or polymorphisms that explain variations in incubation periods and lethality amongst strains belonging to antigenic variants 2 and 3. This information might be used for discussions about the importance of rabies reservoirs, the dynamics of the virus maintenance and evolution of the different forms of this zoonotic disease among infected animals, contributing to further study about the search for molecular markers for pathogenesis.
Zentner, Gabriel Etienne. "Genomic analysis of ribosomal DNA and its application to the investigation of disease pathogenesis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1321478238.
Повний текст джерелаSantana, Estevan Alexis. "Identification of a Fur-regulated small regulatory RNA in nontypeable Haemophilus influenzae." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1410472201.
Повний текст джерелаCunyat, Viaplana Francesc. "Changes in the HIV-1 env gene: Implications at the RNA and protein structure levels." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/96233.
Повний текст джерелаLa glicoproteína de la envuelta (Env) es una de les proteínas claves del VIH-1 en patogénesis. La secuencia del gen env es importante para codificar la Env pero también para las estructuras secundarias de los RREs presentes en sus tránscritos. La relevancia de estos dos elementos ha sido comprobada extensamente, pese a que ensayos funcionales aún son requeridos en ambos casos para estudiar el impacto de cambios específicos. El tratamiento con el inhibidor de fusión T-20 selecciona virus resistentes después de adquirir cambios en el gen env. Para estudiar variantes funcionalmente relevantes de env que se encontraran in vivo decidimos utilizar mutaciones asociadas a T-20. Las predicciones de las estructuras secundarias de los RRE resultaron alteradas en los cambios que codificaban para G36V/D, V38A, Q40H y L45M, pero no para N43D o Q40H-L45M. Funcionalmente demostramos que sólo los mutantes que presentan el cambio L45M en su secuencia sufren un impacto de unión a la proteína viral Rev cuando ésta se encuentra en bajas concentraciones, sugiriendo que los cambios nucleotídicos que afectan a la formación del aminoácido 45 de gp41 juegan un papel en la unión a Rev. No obstante, la capacidad de transporte al citoplasma de estos RRE no está afectada. Por lo tanto, alteraciones en las estructuras secundarias predictivas a partir de secuencias nucleotídicas no necesariamente implican impactos funcionales y la mutación L45M tampoco se incorpora como mutación secundaria debido a la restauración de las funciones del RRE. Como es importante caracterizar funcionalmente Envs derivadas de pacientes para estudiar su patogenicidad, establecimos una metodología completa basándonos en el papel principal de la subunidad gp41. Los resultados demostraron que la línea celular efectora es esencial para optimizar la sensibilidad de los ensayos. La línea celular 293T debería utilizarse para experimentos de fusión y la HeLa per analizar parámetros de citopaticidad. Estudios clínicos habían sugerido que virus que contenían la mutación V38A y el polimorfismo viral N140I estaban asociados a una fallo virológico y beneficios inmunológicos del paciente debido a que eran menos patogénicos. Para entender estos datos discordantes analizamos Envs derivadas de pacientes y vimos que cuando éstas tenían los cambios V38A-N140I tenían menos capacidad para matar células diana de forma individual pese a no tener alterada su capacidad fusogénica. Estos datos remarcan la importancia del contexto de la Env y el papel central de gp41 en la patogénesis del VIH-1.
The Env glycoprotein is one of the key proteins used by HIV-1 to mediate its pathogenicity. The sequence of the env gene is important to encode the Env glycoprotein but also for the secondary structure of the RRE that harbor its transcripts. The relevance of both elements has been extensively proved, although functional assays were needed in both cases to study the impact of specific changes. Treatment with the fusion inhibitor T-20 in patients infected with HIV-1 select resistant viruses to this drug after acquiring changes in their env gene. Therefore, we decided to use T-20-associated changes in order to functionally study relevant in vivo env variants. Predictions of the RRE secondary structures showed alterations when they were encoding for the changes G36V/D, V38A, Q40H and L45M, but not when harboring N43D and Q40H-L45M. Functional data showed that only the mutants harboring the L45M mutation had impairments in their binding capacity to Rev when this protein was at low concentrations, suggesting that the nucleotide changes affecting the encoding of the amino acid 45 in gp41 plays a role in Rev binding. However, none of the RRE variants were affected in their ability to being transported to the cytoplasm. Thus, it was found that alterations in RRE secondary structures predicted from nucleotide sequences might not necessary imply functional impairments and that the L45M change was not incorporated as a secondary mutation due to a restoration of the RRE functions. As it is important to functionally characterize patient-derived Envs to understand their in vivo pathogenesis, we established a complete methodology to study them by focusing on the main role of the subunit gp41. Based on our results, the correct selection of the effector cell line is essential to optimize the sensitivity of the assays. The 293T cell line might be used for fusogenic experiments and the HeLa for analyzing death parameters. Clinical trials had suggested that V38A viral mutants arising in an Env context containing the N140I polymorphism, were low pathogenic due to they were associated with virological failure and immunologic benefits. In order to understand these in vivo discordant data, we used our complete methodology to analyze patient-derived Envs that harbored these changes. We found that the V38A mutant Envs that were arisen in a N140I context were less able to induce single-cell death to target cells despite not having an altered fusogenic capacity. Thus, these data supports the importance of the Env context and the main role of gp41 in HIV-1 pathogenesis.
Wilf, Nabil M. "The role of post-transcriptional regulators in pathogenesis and secondary metabolite production in Serratia sp. ATCC 39006." Thesis, University of Cambridge, 2011. https://www.repository.cam.ac.uk/handle/1810/245284.
Повний текст джерелаDelbianco, Alice. "Molecular mechanisms involved in the pathogenesis of beet soil-borne viruses." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-01017177.
Повний текст джерелаКниги з теми "RNA pathogenesis"
Chistyakova, Guzel, Lyudmila Ustyantseva, Irina Remizova, Vladislav Ryumin, and Svetlana Bychkova. CHILDREN WITH EXTREMELY LOW BODY WEIGHT: CLINICAL CHARACTERISTICS, FUNCTIONAL STATE OF THE IMMUNE SYSTEM, PATHOGENETIC MECHANISMS OF THE FORMATION OF NEONATAL PATHOLOGY. au: AUS PUBLISHERS, 2022. http://dx.doi.org/10.26526/monography_62061e70cc4ed1.46611016.
Повний текст джерелаSelvarajan, Ramasamy, Rajarshi Kumar Gaur, and Basavaprabhu L. Patil. Plant RNA Viruses: Molecular Pathogenesis and Management. Elsevier Science & Technology, 2023.
Знайти повний текст джерелаSelvarajan, Ramasamy, Rajarshi Kumar Gaur, and Basavaprabhu L. Patil. Plant RNA Viruses: Molecular Pathogenesis and Management. Elsevier Science & Technology Books, 2023.
Знайти повний текст джерелаVaheri, Antti, James N. Mills, Christina F. Spiropoulou, and Brian Hjelle. Hantaviruses. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0035.
Повний текст джерелаHughes, Alis, and Lesley Jones. Pathogenic Mechanisms. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0013.
Повний текст джерелаDenton, Christopher P., and Pia Moinzadeh. Systemic sclerosis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0121.
Повний текст джерелаMeng, X. J. Hepatitis E virus. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0048.
Повний текст джерелаWalters, Douglas B., and Lawrence H. Keith. Compendium of Safety Data Sheets for Research and Industrial Chemicals: Flavor and Fragrance Substances (Compendium of Safety Data Sheets for Research). Vch Pub, 1989.
Знайти повний текст джерелаGaston, J. S. Hill. Reactive arthritis and enteropathic arthropathy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0115.
Повний текст джерелаGaston, J. S. Hill. Reactive arthritis and enteropathic arthropathy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0115_update_002.
Повний текст джерелаЧастини книг з теми "RNA pathogenesis"
Guha, Shalini, Priyanka Barman, Aruniti Manawa, and Sukesh R. Bhaumik. "Nuclear Export of mRNAs with Disease Pathogenesis and Therapeutic Implications." In RNA Technologies, 371–95. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08415-7_17.
Повний текст джерелаBishop, David H. L. "Viruses with Ambisense RNA Genomes." In Concepts in Viral Pathogenesis II, 32–39. New York, NY: Springer New York, 1986. http://dx.doi.org/10.1007/978-1-4612-4958-0_4.
Повний текст джерелаPalmenberg, A. C., and J. E. Osorio. "Cardioviral poly(C) tracts and viral pathogenesis." In Positive-Strand RNA Viruses, 67–77. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9326-6_8.
Повний текст джерелаRacaniello, V. R., and R. Ren. "Transgenic mice and the pathogenesis of poliomyelitis." In Positive-Strand RNA Viruses, 79–86. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9326-6_9.
Повний текст джерелаOkada, Yoshimi, Tetsuo Meshi, and Yuichiro Watanabe. "Structure and Functions of Tobacco Mosaic Virus RNA." In Viral Genes and Plant Pathogenesis, 23–38. New York, NY: Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-3424-1_3.
Повний текст джерелаRennick, Linda J., and Paul Duprex. "Modification of Measles Virus and Application to Pathogenesis Studies." In Reverse Genetics of RNA Viruses, 150–99. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118405338.ch6.
Повний текст джерелаHarrison, Stephen C. "Common Features in the Design of Small RNA Viruses." In Concepts in Viral Pathogenesis III, 3–19. New York, NY: Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4613-8890-6_1.
Повний текст джерелаDavis, N. L., F. B. Grieder, J. F. Smith, G. F. Greenwald, M. L. Valenski, D. C. Sellon, P. C. Charles, and R. E. Johnston. "A molecular genetic approach to the study of Venezuelan equine encephalitis virus pathogenesis." In Positive-Strand RNA Viruses, 99–109. Vienna: Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9326-6_11.
Повний текст джерелаNapierala, D., and M. Napierala. "Toxic RNA in Pathogenesis of Human Neuromuscular Disorders." In RNA Technologies in Cardiovascular Medicine and Research, 325–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-78709-9_17.
Повний текст джерелаGerlach, W. L., J. P. Haseloff, M. J. Young, and G. Bruening. "Use of Plant Virus Satellite RNA Sequences to Control Gene Expression." In Viral Genes and Plant Pathogenesis, 177–86. New York, NY: Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-3424-1_18.
Повний текст джерелаТези доповідей конференцій з теми "RNA pathogenesis"
Arnold, Lisa, Shashi Chillappagari, Martina Korfei, Andreas Guenther, and Poornima Mahavadi. "Regulation of RNA Binding Proteins in the Pathogenesis of Lung Fibrosis." In Herbsttagung der Sektion Zellbiologie in der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1678406.
Повний текст джерелаTsers, I., V. Gorshkov, N. Gogoleva, and Y. Gogolev. "Revealing the potential “master regulators” of pathogenesis in plants based on RNA-Seq data." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.254.
Повний текст джерелаOmura, Junichi, Sandra Breuils-Bonnet, Olivier Boucherat, Steeve Provencher, and Sébastien Bonnet. "Long noncoding RNA H19 in the pathogenesis of right ventricular failure with pulmonary arterial hypertension." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3933.
Повний текст джерелаAl-Kershi, S., S. Emmrich, C. Reimer, D. Heckl, and JH Klusmann. "Stem cell-enriched long non-coding RNA HOXA10-AS contributes to the pathogenesis of MLL-rearranged AML." In 30. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch-onkologische Forschung. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1602195.
Повний текст джерелаMumby, S., V. Elyasigomari, C. K. Hui, F. Perros, A. Hautefort, M. Humbert, J. Wort, and I. M. Adcock. "Evidence for Endothelial Barrier Dysfunction, Vascular Permeability and Altered Matrix Degradation in PAH Pathogenesis Using RNA-Sequence Analysis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7194.
Повний текст джерелаChatterji, Priya, Kathryn Hamilton, Sarah Andres, Rei Mizuno, Philip Hicks, Arjun Jeganathan, Monte M. Winslow, et al. "Abstract 1136: Cooperative functional roles of RNA binding proteins LIN28B and IMP1 in the pathogenesis of colorectal cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1136.
Повний текст джерелаCamilleri, Emily T., Pauli J. Beckmann, Jon D. Larson, Morito Kurata, Jingmin Shu, Emily Pope, Wendy A. Hudson, et al. "Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2264.
Повний текст джерелаOmura, J., K. Habbout, S. Martineau, S. Breuils-Bonnet, V. Nadeau, F. Potus, S. L. Archer, et al. "Long Non-Coding RNA H19 in the Pathogenesis of Right Ventricular Failure Associated with Pulmonary Arterial Hypertension -A Putative Novel Biomarker and Therapeutic Target-." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2403.
Повний текст джерелаGuggenbiller, Matthew, Md Sazzad Hassan, Min Yan, Jun Li, Victoria Makuru, and Urs von Holzen. "Abstract 3604: Identification of genes involved in pathogenesis of esophageal adenocarcinoma using RNA sequencing from laser capture micro-dissected formalin-fixed paraffin-embedded tissue specimens." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3604.
Повний текст джерелаRamos, Jairo, and Deodutta Roy. "Abstract 1552: Integrative bioinformatics analyses of ChIP seq and RNA seq data reveals a complex regulatory landscape of NRF1 network involved in the pathogenesis of breast cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1552.
Повний текст джерелаЗвіти організацій з теми "RNA pathogenesis"
Mawassi, Munir, and Valerian Dolja. Role of RNA Silencing Suppression in the Pathogenicity and Host Specificity of the Grapevine Virus A. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7592114.bard.
Повний текст джерелаDawson, William O., Moshe Bar-Joseph, Charles L. Niblett, Ron Gafny, Richard F. Lee, and Munir Mawassi. Citrus Tristeza Virus: Molecular Approaches to Cross Protection. United States Department of Agriculture, January 1994. http://dx.doi.org/10.32747/1994.7570551.bard.
Повний текст джерелаTianzi, Zhang. The Emerging Roles of Long Non-coding RNAs in the Pathogenesis of Breast Cancer. Envirarxiv, November 2022. http://dx.doi.org/10.55800/envirarxiv488.
Повний текст джерелаSionov, Edward, Nancy Keller, and Shiri Barad-Kotler. Mechanisms governing the global regulation of mycotoxin production and pathogenicity by Penicillium expansum in postharvest fruits. United States Department of Agriculture, January 2017. http://dx.doi.org/10.32747/2017.7604292.bard.
Повний текст джерелаXu, Jin-Rong, and Amir Sharon. Comparative studies of fungal pathogeneses in two hemibiotrophs: Magnaporthe grisea and Colletotrichum gloeosporioides. United States Department of Agriculture, May 2008. http://dx.doi.org/10.32747/2008.7695585.bard.
Повний текст джерелаHarman, Gary E., and Ilan Chet. Enhancement of plant disease resistance and productivity through use of root symbiotic fungi. United States Department of Agriculture, July 2008. http://dx.doi.org/10.32747/2008.7695588.bard.
Повний текст джерелаSharon, Amir, and Maor Bar-Peled. Identification of new glycan metabolic pathways in the fungal pathogen Botrytis cinerea and their role in fungus-plant interactions. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597916.bard.
Повний текст джерелаLevisohn, Sharon, Mark Jackwood, and Stanley Kleven. New Approaches for Detection of Mycoplasma iowae Infection in Turkeys. United States Department of Agriculture, February 1995. http://dx.doi.org/10.32747/1995.7612834.bard.
Повний текст джерела