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Статті в журналах з теми "PSCA"
Sun, Shi-Qi, Xiang-Tao Liu, Hui-Chen Guo, Shuang-Hui Yin, You-Jun Shang, Xia Feng, Zai-Xin Liu, and Qing-Ge Xie. "Protective immune responses in guinea pigs and swine induced by a suicidal DNA vaccine of the capsid gene of swine vesicular disease virus." Journal of General Virology 88, no. 3 (March 1, 2007): 842–48. http://dx.doi.org/10.1099/vir.0.82504-0.
Повний текст джерелаArndt, Claudia, Ralf Bergmann, Franziska Striese, Keresztély Merkel, Domokos Máthé, Liliana R. Loureiro, Nicola Mitwasi, et al. "Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management." Cancers 14, no. 8 (April 14, 2022): 1996. http://dx.doi.org/10.3390/cancers14081996.
Повний текст джерелаZou, Qiong, Leping Yang, Zhulin Yang, Jiangsheng Huang, and Xi Fu. "PSCA and Oct-4 Expression in the Benign and Malignant Lesions of Gallbladder: Implication for Carcinogenesis, Progression, and Prognosis of Gallbladder Adenocarcinoma." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/648420.
Повний текст джерелаXiang, Qian, Zhiguo Zhu, Lianmin Luo, Jiamin Wang, Yangzhou Liu, Yihan Deng, Mingda Zhou, and Zhigang Zhao. "The Correlation between PSCA Expression and Neuroendocrine Differentiation in Prostate Cancer." BioMed Research International 2020 (September 24, 2020): 1–9. http://dx.doi.org/10.1155/2020/5395312.
Повний текст джерелаGarcia-Gonzalez, Ulises, Daniel D. Cavalcanti, Abhishek Agrawal, Robert F. Spetzler, and Mark C. Preul. "Anatomical Study on the “Perforator-free Zone”: Reconsidering the Proximal Superior Cerebellar Artery and Basilar Artery Perforators." Neurosurgery 70, no. 3 (September 6, 2011): 764–73. http://dx.doi.org/10.1227/neu.0b013e3182351f8e.
Повний текст джерелаIsomoto, Hajime, Takuki Sakaguchi, Tatsuo Inamine, Shintaro Takeshita, Daisuke Fukuda, Ken Ohnita, Tsutomu Kanda, et al. "SNP rs2920280 in PSCA Is Associated with Susceptibility to Gastric Mucosal Atrophy and Is a Promising Biomarker in Japanese Individuals with Helicobacter pylori Infection." Diagnostics 12, no. 8 (August 16, 2022): 1988. http://dx.doi.org/10.3390/diagnostics12081988.
Повний текст джерелаKim, Sung Han, Weon Seo Park, Sang Jin Lee, Moon Kyung Choi, Seung Min Yeon, Jeong Nam Joo, Ara Ko, et al. "The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/292454.
Повний текст джерелаNejatollahi, Foroogh, Soghra Abdi, and Mahdi Asgharpour. "Antiproliferative and Apoptotic Effects of a Specific Antiprostate Stem Cell Single Chain Antibody on Human Prostate Cancer Cells." Journal of Oncology 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/839831.
Повний текст джерелаHodges, Ron. "How might harmonization influence the future prevalence of public sector creative accounting?" Tékhne 16, no. 1 (November 17, 2018): 3–14. http://dx.doi.org/10.2478/tekhne-2019-0001.
Повний текст джерелаPlé, Sophie, Viviana Job, Andréa Dessen, and Ina Attree. "Cochaperone Interactions in Export of the Type III Needle Component PscF of Pseudomonas aeruginosa." Journal of Bacteriology 192, no. 14 (May 21, 2010): 3801–8. http://dx.doi.org/10.1128/jb.00117-10.
Повний текст джерелаДисертації з теми "PSCA"
Heinrich, Marie-Christine [Verfasser]. "Die PSCA Expression ist mit günstigen Tumoreigenschaften und reduziertem PSA Rezidiv bei operiertem Prostatakarzinom assoziiert / Marie-Christine Heinrich." Hamburg : Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2020. http://d-nb.info/1221084798/34.
Повний текст джерелаNguyen, Minh-Triet [Verfasser]. "PSCA als DNA-Vakzine zur Behandlung des duktalen Pankreaskarzinoms / Minh Triet Nguyen." Bonn : Universitäts- und Landesbibliothek Bonn, 2012. http://d-nb.info/104351094X/34.
Повний текст джерелаGünes, Serap. "MODIFICATION OF VESICULAR STOMATITIS VIRUS G PROTEIN FOR TARGETED GENE DELIVERY INTO PSCA-POSITIVE TUMOR CELLS." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2007. http://nbn-resolving.de/urn:nbn:de:swb:14-1182861723404-04537.
Повний текст джерелаMichen, Susanne. "Armierung von NK-Zellen mit den PSCA-spezifischen chimären Antigenrezeptoren NKp46-αPSCA und NKp46-KiBAP-αPSCA". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-160333.
Повний текст джерелаGünes, Serap. "Modifikation of vesicular stomatitis virus G protein for targeted gene delivery into PSCA-positive tumor cells." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:swb:14-1182861723404-04537.
Повний текст джерелаCREMONESE, Giorgia. "Prostate Stem Cell Antigen (PSCA): a putative target for immunotherapy and diagnosis in prostate, pancreatic and bladder carcinoma." Doctoral thesis, Università degli Studi di Verona, 2010. http://hdl.handle.net/11562/342880.
Повний текст джерелаAntibody-based therapy using unconjugated, toxin-conjugated or radiolabeled immunoglobulins recognizing tumor-associated antigens has proven beneficial for solid and hematolymphoid neoplasms. A suitable target could be prostate stem cell antigen (PSCA), a member of the “GPI-anchored protein”. PSCA is a cell surface-antigen expressed at low levels in normal prostate tissue and over expressed in prostate, pancreatic and bladder carcinomas. Moreover PSCA expression is positively correlated with Gleason score and with pathologic stage in prostate cancer. The present thesis describes the generation and characterization of the murine anti PSCA monoclonal antibody (mAb), obtained by hybridoma technology, and its fragment single chain (scFv), generated by cloning the variable heavy (VH) and light (VL) chain sequences in the expression vector pHEN-2. The mAb showed the ability to recognize with good affinity and specificity the native PSCA by flow cytometry. The diagnostic potential of the mAb was demonstrated by Western Blot performed with prostate and pancreatic neoplastic tissue lysates, showing the binding to denaturated and glycosylated PSCA, and by ELISA performed with fixed cells. The mAb was also assessed for its possible use in the therapeutic approach: the cell-proliferation assay demonstrated that the antibody alone is not able to induce cell death through a direct mechanism, while when it is conjugated to the ricin A chain toxin (RTA) by chemical linkage it can poison PC-3 hPSCA cells with an IC50 (i.e. concentration inhibiting 50% of the maximal cell proliferation) of 1.3x10-9 M, value 100 fold lower than the IC50 of the RTA toxin alone. The scFv was produced in E. Coli bacteria; flow cytometric analysis on PSCA-positive cells and immunoenzymatic assay on the recombinant antigen proved that the antibody fragment maintains the binding specificity of the parental monoclonal antibody. The affinity of the scFv is lower than the affinity of mAb but it is partially recovered making the scFv divalent by cross-linking the scFv monomers via an antibody-mediated myc- Tag interaction. To create a fusion immunotoxin (IT) the scFv was later genetically fused to the enzymatic domain of Pseudomonas aeruginosa exotoxin A (PE40). The resulting IT was expressed in E. Coli bacteria and it is accumulated in the inclusion bodies. The flow cytometric analysis on PSCA-positive cells performed with the whole refolded inclusion bodies extract containing the fusion IT confirmed that the interaction of scFv with the PSCA is preserved after fusion to PE40. The efficacy of purified scFv-PE40 will be analyse in vitro on positive and negative cell lines and subsequently in vivo models which also will be useful to study the side effects of this new drug.
Leyton, Victor Jeffrey. "Engineered antibody fragments for the targeting and imaging of prostate stem cell antigen (PSCA)- expressing xenografts in vivo by microPET." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1624118821&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Повний текст джерелаQuinaud, Manuelle. "Étude structurale et fonctionnelle de PscE : PscF : PscG? un hétérotimère nécessaire à la biogenèse de l'aiguille de sécretion de type III de Pseudomonas aeruginosa." Grenoble 1, 2007. http://www.theses.fr/2007GRE10138.
Повний текст джерелаType III secretion systems are found in several Gram-negative bacteria. These nanomachines are involved in the transport of virulence effectors directly into the cytoplasm of Target cells. Pseudomonas aeruginosa, whose type III secretion needle is studied here, is the causative agent of a large number of nosocomial and chronic infections in cystic fibrosis patients. This system is composed of a base anchored in the double bacterial membrane and a hollow needle formed by a single polymerized protein (PscF in Pseudomonas aeruginosa). Within the bacterial cytoplasm, PscF requires two distinct chaperones for stabilisation before its secretion, without which the entire system is nonfunctionnal. The 2. 0 A X-ray crystal structure orthe PscE:PscF55-85 :PscG ternary complex reveals that the C-terminus of the needle protein PscF, which is essential for needle polymerisation, is engulfed within the hydrophobic groove of the TPR-like molecule PscG. This indicates that the macromolecular scaffold necessary to stabilize the needle protein is totally distinct from T chaperoned complexes between pilus- or flagellum- forming molecules. Disruption of specific PscG:PscF interactions leads to impairement of bacterial cytotoxicity toward macrophages, indicating that This essential heterotrimer, which possesses homologs in a wide variety of pathogens, is an attractive therapeutic Target for the development of novel drugs
Michen, Susanne [Verfasser], Hanns Achim [Akademischer Betreuer] Temme та Gerold [Akademischer Betreuer] Barth. "Armierung von NK-Zellen mit den PSCA-spezifischen chimären Antigenrezeptoren NKp46-αPSCA und NKp46-KiBAP-αPSCA / Susanne Michen. Gutachter: Hanns Achim Temme ; Gerold Barth. Betreuer: Hanns Achim Temme". Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://d-nb.info/1069093149/34.
Повний текст джерелаMorgenroth, Agnieszka. "Herstellung chimärer Rezeptoren zur tumorspezifischen Armierung polyklonaler, zytotoxischer T-Lymphozyten." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1134590060614-48883.
Повний текст джерелаКниги з теми "PSCA"
Boleng, Didimus Tanah. Laporan penelitian studi tentang tanggapan masyarakat terhadap pelaksanaan surveilans acute flaccid paralysis dalam upaya pemantauan kasus poliomyelitis psca [i.e. pasca] PIN tahun 1997. Samarinda: Lembaga Penelitian, Universitas Mulawarman, 2001.
Знайти повний текст джерелаAntunes, Arnaldo. Psia. 3rd ed. São Paulo, Brasil: Iluminuras, 1991.
Знайти повний текст джерелаJusticia, Programa Sociedad Civil y. Acceso a. la. PSCAJ, memoria. La Paz, Bolivia?]: Programa Sociedad Civil y Acceso a la Justicia, 2005.
Знайти повний текст джерелаMagdalena, Moltzan-Małkowska, and Prószyński Media, eds. Psia story. Warszawa: Prószyński Media, 2015.
Знайти повний текст джерелаŠtrelinger, Peter. Psia demokracia: Bájky. Bratislava: Goldpress Publishers, 1993.
Знайти повний текст джерелаMaria, Goudiss, ed. PSSA reading coach. 2nd ed. New York, N.Y: Educational Design, 2001.
Знайти повний текст джерелаIvančević, Olja Savičević. Nasmijati psa. Zagreb: AGM, 2007.
Знайти повний текст джерелаIvančević, Olja Savičević. Nasmijati psa. Zagreb: AGM, 2007.
Знайти повний текст джерелаBegeja, Ksanthipi. The family in the PSRA. New York: Albania Report, 1985.
Знайти повний текст джерелаCikuli, Zisa. Health service in the PSRA. New York: Albania Report, 1985.
Знайти повний текст джерелаЧастини книг з теми "PSCA"
Wente, M. N., A. Jain, P. O. Berberat, T. Giese, H. A. Reber, R. E. Reiter, H. Friess, and M. W. Büchler. "Blockade des Prostata-Stammzellen-Antigens PSCA hemmt das Wachstum des Pankreaskarzioms." In Zurück in die Zukunft, 505–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-55611-1_323.
Повний текст джерелаWente, M. N., A. Jain, P. O. Berberat, T. Giese, H. A. Reber, R. E. Reiter, H. Friess, and M. W. Büchler. "Blockade des Prostata-Stammzellen-Antigens PSCA hemmt das Wachstum des Pankreaskarzinoms." In Deutsche Gesellschaft für Chirurgie, 157–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-19024-7_44.
Повний текст джерелаOh-oka, Hirozo, Saki Kakutani, Shoichiro Kamei, Hiroshi Matsubara, Masayo Iwaki, and Shigeru Itoh. "Photoactive Reaction Center (PscA/Cytochrome c 551)2 Complex of Chlorobium limicola." In Photosynthesis: from Light to Biosphere, 1061–64. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0173-5_250.
Повний текст джерелаMehlhorn, Heinz. "PSAC." In Encyclopedia of Parasitology, 2281. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4214.
Повний текст джерелаMehlhorn, Heinz. "PSAC." In Encyclopedia of Parasitology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4214-1.
Повний текст джерелаPichler, Robert, Johannes Wolfsgruber, Ferdinando Calabria, Orazio Schillaci, and Andreas Dunzinger. "68Ga-PSMA." In Radiopharmaceuticals, 211–25. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-27779-6_12.
Повний текст джерелаGulley, James L. "PSA." In Cancer Therapeutic Targets, 451–58. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4419-0717-2_31.
Повний текст джерелаGulley, James L. "PSA." In Cancer Therapeutic Targets, 1–8. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6613-0_31-4.
Повний текст джерелаvan Balen, J. A. M., A. A. Demeulemeester, M. Frölich, K. Mohrmann, L. M. Harms, W. C. H. van Helden, L. J. Mostert, and J. H. M. Souverijn. "PSA." In Memoboek, 173. Houten: Bohn Stafleu van Loghum, 2012. http://dx.doi.org/10.1007/978-90-313-9129-5_102.
Повний текст джерелаBraun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PSC." In Encyclopedia of Molecular Mechanisms of Disease, 1740. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6791.
Повний текст джерелаТези доповідей конференцій з теми "PSCA"
Tran, Chau P., Scott Knowles, Tove Olafsen, Eric J. Lepin, Anna M. Wu, and Robert E. Reiter. "Abstract 4283: Evaluation of PSCA-specific minibody for in vivo imaging." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4283.
Повний текст джерелаMatsuda, Koichi, Chizu Tanikawa, and Yusuke Nakamura. "Abstract 5063: PSCA as a potential therapeutic and prognostic biomarker for common cancer." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5063.
Повний текст джерелаMoore, Miranda L., Shuai Tang, Mark C. Willingham, and Purnima Dubey. "Abstract B37: PSCA haploinsufficiency enhances prostate tumor growth in prostate-specific Pten knockout mice." In Abstracts: First AACR International Conference on Frontiers in Basic Cancer Research--Oct 8–11, 2009; Boston MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.fbcr09-b37.
Повний текст джерелаBergmann, R., C. Arndt, D. Máthé, N. Berndt, LR Loureiro, N. Kovács, D. Szöllösi, et al. "Copper-64/Actinium-225-human anti-PSCA-IgG4 theranostics of a prostate cancer model." In NuklearMedizin 2021 – digital. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1726705.
Повний текст джерелаTsai, Wen-Ting K., Kirstin A. Zettlitz, Richard Tavaré, Felix B. Salazar, Robert E. Reiter, and Anna M. Wu. "Abstract 1856: Dual-modality immunoPET/fluorescence imaging of prostate cancer utilizing89Zr- or124I-Cy5.5-anti-PSCA cys-minibody." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1856.
Повний текст джерелаIto, Hidemi, Isao Oze, Satoyo Hosono, Miki Watanabe, Hideo Tanaka, and Keitaro Matsuo. "Abstract 2210: Cumulative risks of gastric cancer by PSCA polymorphism, Helicobacter Pylori infection and smoking history in Japan." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2210.
Повний текст джерелаHess, T., L. Hamann, YK Vashist, K. Butterbach, T. Schmidt, I. Krasniuk, A. Höblinger, et al. "Evidence for PTGER4, PSCA and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1604759.
Повний текст джерелаGalindo, Hector G., Milind Suraokar, Carmen Behrens, Denise M. Woods, Neda Kalhor, Kenneth D. Aldape, Junya Fujimoto, Roy S. Herbst, Heidi S. Erickson, and Ignacio I. Wistuba. "Abstract 5166: Identification of prostate stem cell antigen (PSCA) as a potential marker for lung cancer brain metastasis." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-5166.
Повний текст джерелаAbate-Daga, Daniel, Kiran H. Lagisetty, Luca Gattinoni, Zhiya Yu, Nicholas P. Restifo, Steven A. Rosenberg, and Richard A. Morgan. "Abstract 3966: Development of a fully-human chimeric antigen receptor against PSCA for the treatment of pancreatic cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3966.
Повний текст джерелаNavas, Tony, Trisha Haubrich, Jenny Llamas, Hector Avina, Zhang Chunying, Myra Perez, Linnette Capo, et al. "Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4566.
Повний текст джерелаЗвіти організацій з теми "PSCA"
Reiter, Robert E. Mechanisms and Refinements of PSCA Directed Antibody Therapy. Fort Belvoir, VA: Defense Technical Information Center, January 2003. http://dx.doi.org/10.21236/ada413309.
Повний текст джерелаReiter, Robert E. Mechanisms and Refinements of PSCA Directed Antibody Therapy. Fort Belvoir, VA: Defense Technical Information Center, March 2004. http://dx.doi.org/10.21236/ada426030.
Повний текст джерелаReiter, Robert. A PSCA Promoter Based Avian Retroviral Transgene Model of Normal and Malignant Prostate. Fort Belvoir, VA: Defense Technical Information Center, April 2004. http://dx.doi.org/10.21236/ada429113.
Повний текст джерелаReiter, Robert. A PSCA Promoter Based Avian Retroviral Transgene Model of Normal and Malignant Prostate. Fort Belvoir, VA: Defense Technical Information Center, April 2006. http://dx.doi.org/10.21236/ada460465.
Повний текст джерелаReiter, Robert E. Prostate stem Cell Antigen (PSCA): A Promising Marker and Therapeutic Target in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2002. http://dx.doi.org/10.21236/ada412761.
Повний текст джерелаReiter, Robert E. Prostate Stem Cell Antigen (PSCA): A Promising Prognostic Marker and Therapeutic Target in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2003. http://dx.doi.org/10.21236/ada419393.
Повний текст джерелаNair, Smita. Prostate Cancer Immunotherapy by Targeting Dendritic Cells In Vivo Using Receptor-Specific Aptamer Conjugated to Prostate Stem Cell Antigen (PSCA)-Encoding RNA. Fort Belvoir, VA: Defense Technical Information Center, August 2011. http://dx.doi.org/10.21236/ada551308.
Повний текст джерелаBochert, Monika. PSCR Impact Assessment:. Gaithersburg, MD: National Institute of Standards and Technology, 2023. http://dx.doi.org/10.6028/nist.gcr.23-038.
Повний текст джерелаMuljadi, E., M. Singh, and V. Gevorgian. PSCAD Modules Representing PV Generator. Office of Scientific and Technical Information (OSTI), August 2013. http://dx.doi.org/10.2172/1096111.
Повний текст джерелаNadeau, Lou, Melanie Sands, Douglas Lyons, and Clara Berger. NIST PSCR: Economic Impact Analysis. National Institute of Standards and Technology, June 2021. http://dx.doi.org/10.6028/nist.gcr.21-031.
Повний текст джерела