Готові списки джерел за темами / Physical comorbidity

Зміст

Статті в журналах
Дисертації
Книги
Частини книг
Тези доповідей конференцій
Звіти організацій

Добірка наукової літератури з теми "Physical comorbidity"

Автор: Grafiati

Опубліковано: 11 березня 2023

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями

Оберіть тип джерела:

Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Physical comorbidity".

Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.

Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.

Статті в журналах з теми "Physical comorbidity"

Williams, Shehan, and Thilini Rajapakse. "Physical illness and psychiatric comorbidity." Sri Lanka Journal of Psychiatry 4, no. 1 (July 3, 2013): 22. http://dx.doi.org/10.4038/sljpsyc.v4i1.5725.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Sharma, MahendraP. "Comorbidity of mental and physical disorders." Indian Journal of Medical Research 144, no. 5 (2016): 786. http://dx.doi.org/10.4103/0971-5916.203466.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Lauber, C. "ECP04-01 - Physical and mental comorbidity." European Psychiatry 27 (January 2012): 1. http://dx.doi.org/10.1016/s0924-9338(12)74092-0.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Qin, Ping, Keith Hawton, Preben Bo Mortensen, and Roger Webb. "Combined effects of physical illness and comorbid psychiatric disorder on risk of suicide in a national population study." British Journal of Psychiatry 204, no. 6 (June 2014): 430–35. http://dx.doi.org/10.1192/bjp.bp.113.128785.

Повний текст джерела

Анотація:

BackgroundPeople with physical illness often have psychiatric disorder and this comorbidity may have a specific influence on their risk of suicide.AimsTo examine how physical illness and psychiatric comorbidity interact to influence risk of suicide, with particular focus on relative timing of onset of the two types of illness.MethodBased on the national population of Denmark, individual-level data were retrieved from five national registers on 27 262 suicide cases and 468 007 gender- and birth-date matched living controls. Data were analysed using conditional logistic regression.ResultsBoth suicides and controls with physical illness more often had comorbid psychiatric disorder than their physically healthy counterparts. Although both physical and psychiatric illnesses constituted significant risk factors for suicide, their relative timing of onset in individuals with comorbidity significantly differentiated the associated risk of suicide. While suicide risk was highly elevated when onsets of both physical and psychiatric illness occurred close in time to each other, regardless which came first, psychiatric comorbidity developed some time after onset of physical illness exacerbated the risk of suicide substantially.ConclusionsSuicide risk in physically ill people varies substantially by presence of psychiatric comorbidity, particularly the relative timing of onset of the two types of illness. Closer collaboration between general and mental health services should be an essential component of suicide prevention strategies.

Стилі APA, Harvard, Vancouver, ISO та ін.

Joshi, R. G., D. R. Shakya, P. M. Shyangwa, and B. Pradhan. "Co-morbidity in women with alcohol dependence syndrome (ADS) in Eastern Nepal." Journal of Psychiatrists' Association of Nepal 5, no. 1 (September 29, 2017): 18–21. http://dx.doi.org/10.3126/jpan.v5i1.18326.

Повний текст джерела

Анотація:

Introduction: Women with ADS may have psychiatric comorbidites along with physical comorbidities. Societal attitudes towards women and alcohol are barriers to the detection and treatment of their alcohol related problems.Objective: To explore the magnitude of co-morbidity among women with ADS in Eastern Nepal.Method: This is a hospital based cross-sectional study of women with ADS. Those who scored two or more than two in T-ACE questionnaire were enrolled. The diagnosis was made according to ICD-10 criteria. Consultation with concerned physician was done to assess physical condition.Result: Fifty one patients with ADS were enrolled. Among them, 21.6% had no comorbidity, 52.9% had single co-morbidity (psychiatric or physical) and 25.5% had both psychiatric and physical co-morbidity. In psychiatric comorbidity, mood disorder in 35.29% was the commonest followed by nicotine use in 26.47%. Among mood disorders 83.3% had depression. In physical comorbidity, disease of gastrointestinal tract and hepatobiliary system in 50.9% was the commonest followed by hypertension in 11.5%.Conclusion: : Psychiatric as well as physical co-morbidities are common in women with ADS. The finding points to the importance of exploring comorbidities and their optimal treatment.

Стилі APA, Harvard, Vancouver, ISO та ін.

Chadda, RK, KN Nishanth, M. Sood, A. Biswas, and R. Lakshmy. "Physical comorbidity in schizophrenia & its correlates." Indian Journal of Medical Research 146, no. 2 (2017): 281. http://dx.doi.org/10.4103/ijmr.ijmr_1510_15.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Aragonès, Enric, Josep L. Piñol, and Antonio Labad. "Depression and physical comorbidity in primary care." Journal of Psychosomatic Research 63, no. 2 (August 2007): 107–11. http://dx.doi.org/10.1016/j.jpsychores.2007.05.008.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Kisely, S. R., and D. P. Goldberg. "Physical and Psychiatric Comorbidity in General Practice." British Journal of Psychiatry 169, no. 2 (August 1996): 236–42. http://dx.doi.org/10.1192/bjp.169.2.236.

Повний текст джерела

Анотація:

BackgroundThe aim of this study was to determine the association between physical and psychiatric morbidity among general practice patients and to explore the influence of possible intervening variables.MethodPhysical and psychiatric morbidity in 1620 consecutive patients attending their general practitioner (GP) was assessed using a two-stage design. Ninety-four per cent of the patients (n=1523) were successfully screened using the General Health Questionnaire (GHQ–12); 428 of the 602 patients (71%) eligible for the second stage were interviewed using the Composite International Diagnostic Instrument adapted for use in primary health care (CIDI–PHC), the Brief Disability Questionnaire (BDQ) and the Groningen Social Disability Schedule (GSDS) to assess psychiatric, physical and social status. Assessments of physical and psychiatric morbidity were also obtained from the patients' GPs.ResultsThere was a significant association between physical and psychiatric morbidity, although patients with four symptoms or less of physical illness were no more likely to be psychiatric cases than those with none. The association was accounted for by patients at the severe end of the physical continuum with five or more medically explained somatic symptoms: these were twice as likely to be psychiatric cases as those with no such symptoms. Female gender, social disability and physical disability were all significantly more likely to be associated with psychiatric disorder, whether measured by GP or research interview; and these relationships remained after the data were corrected for age differences.ConclusionsPatients in general practice with moderate to severe physical morbidity are at increased risk of developing psychiatric illness, and when medical illness is present, psychiatric symptoms are more severe. As physical and psychiatric comorbidity is relatively common in general practice, the specific needs of these patients should receive greater attention.

Стилі APA, Harvard, Vancouver, ISO та ін.

Pestana Santos, A., and J. Amílcar Teixeira. "Medical Comorbidity in Schizophrenia." European Psychiatry 41, S1 (April 2017): S276. http://dx.doi.org/10.1016/j.eurpsy.2017.02.114.

Повний текст джерела

Анотація:

People with schizophrenia have higher prevalence of physical disease and its lifespan is shortened when compared with general population. On average, they die 10 to 25 years earlier than general population.AimThe authors aim to identify the main comorbidities in people with schizophrenia and define strategies to prevent it.MethodsLiterature review on Medline database.ResultsPeople with schizophrenia have higher risk to have hepatitis, cardiovascular diseases, diabetes, overweight, sexual dysfunction and obstetric complications. This high vulnerability is associated with higher rates of preventable risk factors, such as smoking, alcohol consumption, use of street drugs, poor dietary habits and lack of exercise. Moreover, some antipsychotic medications used to treat schizophrenia have been associated with higher incidence of physical disease. At last, there are risk factors attributable to patients and healthcare services. Psychiatrists are often not trained in detection and treatment of physical disease. Despite this, there are several attitudes that can reduce the associated morbidity and mortality in people with schizophrenia, such as improving access to healthcare services, integrated healthcare interventions to enable early diagnosis and promotion of healthy habits.ConclusionsDiagnosis and management of morbidity in people with schizophrenia are more difficult because obstacles related to the patient, the illness, the medical attitudes and the structure of the healthcare services. Regardless these difficulties, the increased frequency of physical disease in people with schizophrenia must be valued due to improved detection and treatment of medical disease will have significant benefits for their psychosocial function and overall quality of life.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Стилі APA, Harvard, Vancouver, ISO та ін.

Heun, R., and D. Schoepf. "Physical comorbidity and consequences for mortality and treatment." European Psychiatry 33, S1 (March 2016): S39. http://dx.doi.org/10.1016/j.eurpsy.2016.01.882.

Повний текст джерела

Анотація:

IntroductionAgeing is related to an increase rate of physical comorbidity. However, the interaction between physical comorbidity and the development of depression in the elderly is not yet clear. Depression may be the cause or consequence of physical morbidity. Both may increase mortality.MethodsA total of 9604 patients with depression and a control sample of 96040 patients who attended a general hospital were followed-up for up to 12 years. Physical comorbidity and mortality was assessed.ResultsTwenty-nine physical disorders were more prevalent in subjects with depression, but the effect of individual disorders on mortality did not differ significantly in the depressed and control sample.ConclusionsPatients with depression suffer more physical health problems than control patients that lead to death. The implications for early treatment will be discussed, a preventative approach may be most relevant.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Стилі APA, Harvard, Vancouver, ISO та ін.

Більше джерел

Дисертації з теми "Physical comorbidity"

Aschan, Lisa. "Health inequalities and mental health service use in mental-physical comorbidity." Thesis, King's College London (University of London), 2015. https://kclpure.kcl.ac.uk/portal/en/theses/health-inequalities-and-mental-health-service-use-in-mentalphysical-comorbidity(6f2c678e-1d94-40c0-9622-333539e46c4b).html.

Повний текст джерела

Анотація:

Although mental and physical health are likely to share common social causes, most mental-physical comorbidity research has focused on immediate mechanisms between mental and physical illness. This thesis takes a social epidemiological approach to mental-physical comorbidity, where social disadvantage and the disproportionate availability of resources are central. The amplified burden of comorbidity in terms of poor health and functioning may have implications for the relationship between comorbidity and mental health service use (MHSU). Whilst much research examines the impact of comorbidity on physical health services, MHSU is under-researched. Furthermore, comorbidity inequalities may be perpetuated through processes of cumulative disadvantage. For example, barriers to social participation may deplete resources over time, thus leading to worse health outcomes and more adverse social circumstances. This project therefore aims to: 1. Estimate the prevalence of comorbidity, and describe inequalities in mental-physical comorbidity by key socio-demographic and socioeconomic factors 2. Describe and explain the association between comorbidity and mental health service utilisation and quality 3. Describe the trajectories of social functioning by comorbidity Analyses make use of survey data from the South East London Community Health Survey (SELCoH) phases 1 (N=1698) and 2 (N=1052) (73% response among those approached at follow-up). Statistical methods used include weighted cross-sectional and longitudinal regression analyses. The results indicate that comorbidity is associated with distinct socio-economic inequalities (most consistently by household income), increased MHSU over time, and persistent social exclusion. This suggests that comorbidity reflects a process of cumulative disadvantage, which has important implications for comorbidity and health inequality research, and local services and policy makers. Altering the downward spiralling trajectories of health and social disadvantage among those with mental-physical comorbidity may be addressed through integrated care models, while interventions aimed at reducing social inequalities may effectively 3 prevent comorbidity and interrupt its downward spiralling course of disadvantage.

Стилі APA, Harvard, Vancouver, ISO та ін.

McNamara, Renae J. "Effect of water-based exercise in people with COPD with physical comorbidities." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/13271.

Повний текст джерела

Анотація:

People with chronic obstructive pulmonary disease (COPD) and physical comorbidities such as obesity, musculoskeletal, orthopaedic and neurological conditions have reduced free-living daily physical activity compared to people with COPD and healthy age-matched individuals. Less time is spent in light and moderate intensity physical activity and greater time is spent in sedentary behaviours. Water-based exercise training (WBET) may be an alternative to traditional land-based exercise training (LBET) for people with COPD and physical comorbidities (COPD+PC). Previous studies have shown positive outcomes for exercise capacity and quality of life following WBET, however these results were inconclusive given the trials were low in quality. In a prospective randomised controlled trial comparing an eight-week supervised WBET program to an equivalent eight-week supervised LBET program and a control group of no exercise training, WBET was found to be significantly more effective than LBET and no exercise training in increasing peak and endurance exercise capacity and improving aspects of quality of life in people with COPD+PC. In addition, obese participants randomised to the WBET program lost a greater amount of weight over the eight-week training period than participants in the LBET and no exercise training groups. WBET was found to be well accepted by people with COPD+PC, with no adverse events occurring during the training period. Furthermore, high satisfaction with the aquatic environment was reported. In a Cochrane review examining the effect of WBET in people with COPD, WBET was found to significantly improve exercise capacity (functional, peak and endurance exercise capacity) and quality of life compared to no exercise training. Compared to LBET, WBET was found to significantly improve endurance exercise capacity and fatigue. Limited quality evidence exists that WBET in people with COPD is safe and effective.

Стилі APA, Harvard, Vancouver, ISO та ін.

Andersson, Mikael. "Assessing Physical Activity and Physical Capacity in Subjects with Chronic Obstructive Pulmonary Disease." Doctoral thesis, Uppsala universitet, Sjukgymnastik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-220602.

Повний текст джерела

Анотація:

The overall aim of this thesis was to assess measurement properties of methods suitable for screening or monitoring of physical capacity and physical activity in subjects with chronic obstructive pulmonary disease (COPD), and to explore factors associated with physical activity levels. Methods: Four observational studies were conducted. Participants in studies I-III (sample sizes) (n=49, n=15, n=73) were recruited from specialist clinics, and in study IV from a population-based cohort (COPD n=470 and Non-COPD n=659). Psychometric properties of methods assessing physical capacity (study I) and physical activity (study II) were investigated in laboratory settings. Daily physical activity and clinical characteristics were assessed with objective methods (study III) and with subjective methods (study IV). Results: Physical capacity as measured by walking speed during a 30-metre walk test displayed high test-retest correlations (ICC>0.87) and small measurement error. The accuracy for step count and body positions differed between activity monitors and direct observations. In study III 92% of subjects had an activity level below what is recommended in guidelines. Forty five percent of subjects’ activity could be accounted for by clinical characteristics with lung function (22.5%), walking speed (10.1%), quadriceps strength (7.0%) and fat-free mass index (3.0%) being significant predictors. In study IV, low physical activity was significantly more prevalent in COPD subjects from GOLD grade ≥II than among Non-COPD subjects (22.4 vs. 14.6%, p = 0.016). The strongest factors associated with low activity in COPD subjects were a history of heart disease, OR (CI 95%) 2.11 (1.10-4.08) and fatigue, OR 2.33 (1.31-4.13) while obesity was the only significant factor in Non-COPD subjects, OR 2.26 (1.17-4.35). Conclusion: The 30 meter walk test and activity monitors are useful when assessing physical capacity and physical activity, respectively in patients with COPD. Impaired physical activity in severe COPD is related to low lung function, low walking speed, low muscle strength and altered body composition, whereas comorbidities and fatigue are linked to insufficient physical activity in patients with moderately severe COPD.

Стилі APA, Harvard, Vancouver, ISO та ін.

Prior, James Andrew. "Consequences of cardiovascular disease and osteoarthritis comorbidity on short and long-term physical health change in general practice." Thesis, Keele University, 2013. http://eprints.keele.ac.uk/206/.

Повний текст джерела

Анотація:

Comorbidity is defined as experiencing an ‘index’ health condition with one or more other conditions at the same time. The prevalence of comorbidity, in particular chronic disease comorbidity, is set to rise in ageing Western populations and negatively influences patient health and health care services. However, our understanding of how specific comorbid chronic disease combinations (such as cardiovascular disease and osteoarthritis) interact, the subsequent outcomes and how severity influences these remains limited. The aim of this thesis was to investigate the consequences of cardiovascular disease and osteoarthritis comorbidity on short and long-term physical health change in general practice populations.

Стилі APA, Harvard, Vancouver, ISO та ін.

Penman, Jean. "Engaging with persistent medically unexplained physical symptoms in healthcare : a realist psychosexual service evaluation." Thesis, University of Bedfordshire, 2015. http://hdl.handle.net/10547/622044.

Повний текст джерела

Анотація:

In this study the phenomenon of persistent physical symptoms (PPS) has been examined by realist evaluation of research and practice. Nimnuan et al., (2001) have shown that up to 35% of patients in primary care and 66% in specialist out-patient clinics have presented with such ‘medically unexplained’ symptoms. The cost in medical investigation to reach diagnosis for PPS is an estimated 10% of the annual UK National Health Service budget (Bermingham et al., 2010) but poor patient outcomes prevail (Dwamena et al., 2009). Currently, PPS is linked to high comorbidity with anxiety and depression (DH 2011b) and Cognitive Behavioural Therapy (CBT) is advised as the evidence based treatment for PPS (IAPT, 2014). However, a shortfall in clinical skills to address PPS is also demonstrated and engagement could be improved (De Lusignan et al., 2014). Moreover, the pragmatic study of alternative therapy modalities and processes for PPS is recommended (Leichsenring, 2005). To obtain a broader knowledge of process for patients with or without co-morbidity, practice based experience suggests that one such alternative is a brief psychodynamic intervention (STPP) for PPS. A Realist Literature Synthesis (Wong et al. 2013) highlights effective psychotherapeutic STPP interventions in real world circumstances in 5 comparison with CBT interventions for heterogenous PPS. STPP for PPS is found at least as effective as CBT, with improved engagement rates. Additionally, common factors were discovered between ‘third generation’ STPP and CBT for effective PPS interventions and these were developed into a preliminary cross-modality theoretical analytical framework. In the realist contextual evaluation (Pawson and Tilley, 1997) of a psychosexual service delivery, the majority of PPS sufferers were found only moderately co-morbid with anxiety and depression. For complete investigative study, clinical tools are developed providing integrative CBT/STPP principles for engagement with PPS for teaching, training and practice. In conclusion, the findings suggest that the reflexive insider position of the realist Therapist-Evaluator facilitates systematically derived Practice-Based Evidence of PPS process, meeting recommendations of Deary et al., (2007) to explore and define process and outcomes with PPS. The findings contribute to development of a conceptual platform to support health professionals in overcoming physical/mental health barriers to addressing PPS and wider patient access to effective care (NHSE, 2014, 2015).

Стилі APA, Harvard, Vancouver, ISO та ін.

Telford, Robin. "Physical and Mental Health Status of Adults with Serious Mental Illness Participating in a Jail Diversion Intervention." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5139.

Повний текст джерела

Анотація:

Adults with mental illnesses are at an increased risk to be diagnosed with one or more comorbid physical illnesses compared to the general population. Much of the disparities faced by adults with serious mental illnesses (SMI) can be attributed to medication side effects, increased risk for metabolic diseases, inability to communicate about severity and monitor physical health symptoms, poor health behaviors, high rates of smoking, and poor quality health care. The rate of physical illnesses for adults with mental illnesses are even higher among those who have been involved with the criminal justice system. In order to understand the relationship between physical and mental illnesses, longitudinal study designs are needed. Longitudinal studies can provide greater understanding of the temporal relationship of physical and mental illnesses. Despite the benefits of longitudinal studies, there also are challenges, including missing data. The first manuscript of this dissertation explores the physical and mental health status of adults with mental illnesses. Secondary data were used from three different studies: a sample of adults with SMI enrolled in a mental health court jail diversion program (n=91); a sample of Medicaid enrollees with SMI in Florida (n=688) who were part of a larger Substance Abuse and Mental Health Services Administration (SAMHSA) study; and a sample of inpatient and outpatient adults with SMI from five different study sites (n=969). The samples were combined into two data sets, consisting of the jail diversion sample and the SAMHSA sample, and the jail diversion sample and the 5-site sample. Participants in these samples answered questions on the Short-Form Health Survey (SF-12), recent arrests, drug and alcohol use, socio-demographic information, and mental illness symptom severity (measured only in the criminal justice and 5-site samples). Overall, the mental and physical health status scores were significantly lower for all of the participants compared to the general population mean scores. The participants reporting a recent arrest had a higher physical health score compared to those who did not have a recent arrest, and in the jail diversion and 5-site sample, had a lower mental health status score than those without a recent arrest. After taking age, drug and alcohol use, and psychiatric symptom severity into account, arrest was no longer associated with the physical health status score in either of the data sets. In the jail diversion and 5-site data set, arrest was still significantly associated with mental health status score after controlling for age, drug and alcohol use, and psychiatric symptom severity. The second manuscript of this dissertation explores the analysis of missing data in a longitudinal study to determine the missing data mechanisms and missing data patterns, and subsequently, how to prepare the data for analysis by using multiple imputation or maximum likelihood estimation. Secondary data were drawn from the same jail diversion sample as in the first manuscript. Data were collected at baseline, three months, six months, and nine months. Only participants with the potential to have data collected at these time points were included (n=50). Analysis revealed missing data due to missing item-level information, missing participant data at one time point but complete data at a subsequent time point, and missing participant data for those who dropped out of the study completely. The missing data mechanism for the missing item-level data were missing completely at random, whereas the participant-level missing data were missing at random. Multiple imputation was used for the item-level data and for the participant-level missing data. Maximum likelihood estimation was also used for the participant-level missing data and compared to the multiple imputation results. Findings suggest that multiple imputation produced more accurate parameter estimates, possibly due to the small sample size. The findings from this study indicate that more research needs to be done to fully understand the physical illnesses experienced by adults with mental illnesses who are involved with the criminal justice system. Understanding mental and physical illness comorbidity is important in public health as it dictates appropriate treatments and training for behavioral health practitioners and staff. In addition, missing data in longitudinal studies cannot be ignored, as it can bias the results, and appropriate techniques for exploring the missing data must be used. When missing data is ignored in analyses, the subsequent results can be incorrect and unable to detect treatment effects, thereby preventing effective programs from receiving necessary funding. In addition, ignoring missing data can impact funding for behavioral health services by underestimating the prevalence and severity of mental illnesses. Future research should focus on exploring how mental and physical health are related in adults with a recent arrest compared to the general population, and ways to integrate services to address both mental and physical health.

Стилі APA, Harvard, Vancouver, ISO та ін.

Marques, Wanessa Vieira. "Influência das comorbidades na capacidade funcional de pacientes com artrite reumatoide." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/3439.

Повний текст джерела

Анотація:

Submitted by Cássia Santos (cassia.bcufg@gmail.com) on 2014-10-21T11:09:00Z No. of bitstreams: 2 Dissertacao Mestrado Final Wanessa Vieira Marques - 2014.pdf: 2424315 bytes, checksum: 43cfe85410f8246c32e9c3194794b2d6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)
Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2014-10-23T11:19:39Z (GMT) No. of bitstreams: 2 Dissertacao Mestrado Final Wanessa Vieira Marques - 2014.pdf: 2424315 bytes, checksum: 43cfe85410f8246c32e9c3194794b2d6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)
Made available in DSpace on 2014-10-23T11:19:39Z (GMT). No. of bitstreams: 2 Dissertacao Mestrado Final Wanessa Vieira Marques - 2014.pdf: 2424315 bytes, checksum: 43cfe85410f8246c32e9c3194794b2d6 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2014-04-03
Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq
Patients with rheumatoid arthritis (RA) present higher prevalence of comorbidities. Such comorbidities are associated with different outcomes in RA patients, such as mortality risk, increase in disability, impact on RA specific treatment and higher medical costs. The purpose of this study was to assess the influence of comorbidities on the functional capacity and mobility of the affected individuals, and to identify, among the comorbidity indicators, the most appropriate to determine association between comorbidities and physical function on these patients. In a cross-sectional study we included 60 patients with RA fulfilling the American College of Rheumatology criteria (ACR, 1987) over a period of 11 months, both male and female between 43 and 80 years old. Comorbidities were assessed by means of three indicators: (i) total number of comorbidities (NCom) reported by the patients and listed on their medical records; (ii) the Charlson comorbidity index (CCI); and (iii) the functional comorbidity index (FCI). The activity of disease was evaluated by the Disease Activity Score, based on 28 joints and erythrocyte sedimentation rate value (DAS28/ESR). The participants’ functional capacity was measured using the Health Assessment Questionnaire (HAQ), and their mobility was measured using the chairrising test (CRT) and timed get up and go (TUG) test. Statistical analysis was performed using Log-Linear Stepwise multiple regression at 5% significance level. The prevalence of comorbidities in the investigated sample of patients with RA was 90% when the total number of comorbidities (NCom) was taken into consideration. In the final multiple regression model, the independent factors that influenced functional capacity (HAQ) were activity of disease (DAS28/ESR) and comorbidities, as assessed by FCI, which explained together 32.9% of the HAQ score variability (adjusted coefficient of determination [R2] = 0.329). With respect to the participants’ mobility (CRT and TUG), in the final model, only the independent factor comorbidities (FCI) exerted a significant influence on the results. The FCI scores explained 19.1% of the CRT variability (R2= 0.191) and 19.5% of the TUG variability (R2= 0.195). Among the comorbidity indicators used, the FCI was the main responsible for explain the physical function (HAQ) and mobility (CRT and TUG) variability at the final model in our sample. Comorbidities were highly prevalent in individuals with RA and exerted a negative influence on their functional capacity and mobility. FCI proved to be appropriate to determine the association between comorbidities and physical function in individuals with RA.
Pacientes com artrite reumatoide (AR) apresentam prevalência aumentada de comorbidades. A presença de comorbidades está associada a um pior desfecho clínico nesses indivíduos, tais como risco de mortalidade, comprometimento na funcionalidade, interferência no tratamento específico da AR e aumento nos custos médicos. O objetivo deste estudo foi investigar a influência das comorbidades na capacidade funcional e na mobilidade em pacientes com AR, e identificar, dentre os indicadores de comorbidade, aquele mais apropriado para determinar a associação entre comorbidades e desfecho funcional nesses indivíduos. Trata-se de um estudo transversal com a participação de 60 pacientes classificados com AR pelos critérios da American College of Rheumatology (ACR) de 1987 em um período de 11 meses, de ambos os gêneros e faixa etária entre 43 e 80 anos. As comorbidades foram avaliadas por meio de três indicadores: (i) número total de comorbidades (NCom) relatadas pelos pacientes e anotadas em prontuário médico; (ii) escore obtido no índice de comorbidade de Charlson (ICC); e escore obtido no índice de comorbidade funcional (ICF). A atividade da doença foi mensurada pelo Índice de Atividade da Doença baseado em 28 articulações e no valor do VHS (Disease Activity Score 28 – DAS28/VHS). A capacidade funcional e a mobilidade foram avaliadas por meio do escore obtido no Questionário de Avaliação da Saúde (Health Assessment Questionnaire – HAQ), no teste senta-levanta da cadeira cinco vezes (TSL) e no teste timed get up and go (TUG). A análise estatística dos dados foi realizada através de regressão múltipla Log-Linear Stepwise com nível de significância de 5%. Observou-se que a prevalência das comorbidades, analisada pelo indicador número total de comorbidades (NCom), foi de 90% em nossa amostra. No modelo final da análise múltipla os fatores determinantes da capacidade funcional (HAQ) foram a atividade da doença (DAS28/VHS) e as comorbidades, avaliadas pelo ICF, que em conjunto explicaram 32,9% da variabilidade do escore do HAQ (coeficiente de determinação [R2] ajustado = 0,329). Com relação à mobilidade (TSL e TUG), no modelo final, apenas as comorbidades (ICF) influenciaram significativamente o seu desempenho. O escore no ICF explicou 19,1% da variabilidade do TSL (R2 = 0,191)e 19,5% da variabilidade do TUG (R2 = 0,195). Dentre os indicadores de comorbidade utilizados, o indicador ICF foi o principal responsável por explicar no modelo final a variabilidade da capacidade funcional (HAQ) e da mobilidade (TSL e TUG) em nossa amostra. Conclui-se que as comorbidades são frequentes em pacientes com AR e influenciam negativamente a capacidade funcional e a mobilidade desses indivíduos. O ICF demonstrou ser um indicador de comorbidade apropriado para determinar a associação entre comorbidades e funcionalidade em pacientes com AR.

Стилі APA, Harvard, Vancouver, ISO та ін.

Gybrant, Gustav, and Pegita Seyedi. "KBT-I FÖR DEPRESSION : Är Kognitiv Beteendeterapi för Insomni (KBT-I) en effektiv behandling för depression – vid samtidig förekomst av insomni?" Thesis, Örebro universitet, Institutionen för juridik, psykologi och socialt arbete, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-33730.

Повний текст джерела

Анотація:

Depression och insomni är två vanliga former av psykisk ohälsa. I den här studien undersöktes om en bevisat effektiv behandling för insomni, (KBT-I), påverkade grad av depressiva symtom hos personer med konstaterade symtom på såväl depression som insomni. I studien kontrollerades för en minskning av nedstämdhet kunde tillskrivas en ökad fysisk aktivitetsnivå. En single case experimental design användes för ändamålet, med dagliga skattningar av sömn, nedstämdhet och fysisk aktivitetsnivå. Symtom på såväl insomi som nedstämdhet minskade signifikant hos tre av sex deltagare. Minskad nedstämdhet kunde inte förklaras av ökad fysisk aktivitetsnivå. Samvariation observerades mellan depression och insomni. Resultaten visar att insomni och depression kan påverkas av samma behandling, vilket antyder förekomst av gemensamma vidmakthållande mekanismer.
Insomnia and depression are two common mental health problems. This study investigated whether a proven effective treatment for insomnia CBT-I, would change the severity of depressive symptoms, for participants with comorbid insomnia and depression. It was controlled for, whether a reduction in depressive symptoms could be the result of increased physical activity. A single case experimental design, including daily measurements of sleep, depression and physical activity, was used as a means to answer the research questions. Symptoms of both depression and insomnia were significantly reduced for three out of six participants. Increased physical activity was not able to explain the decrease in depression scores. A correlation was observed, between depression and insomnia. The results shows that insomnia and depression can be affected by the same treatment, which implies existence of common perpetual mechanisms.

Стилі APA, Harvard, Vancouver, ISO та ін.

Alberte, Josiane Souza Pinto. "Fatores biopsicossociais no envelhecimento e percepção da qualidade de vida do idoso." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310907.

Повний текст джерела

Анотація:

Orientador: Maria Elena Guariento
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
Made available in DSpace on 2018-08-14T03:48:42Z (GMT). No. of bitstreams: 1 Alberte_JosianeSouzaPinto_D.pdf: 6193745 bytes, checksum: 00fa9fe29e50c34be0a72f6988e849f4 (MD5) Previous issue date: 2009
Resumo: Em vista da relevância que adquire o parâmetro qualidade de vida entre os indivíduos que estão envelhecendo, desenvolveu-se este trabalho que tem por objetivo avaliar e comparar os fatores que interferem na percepção da qualidade de vida (PQV) de dois grupos distintos de idosos que requerem um suporte institucional de duas instituições diferentes. Foram avaliados cento e seis pacientes entre sessenta e oitenta anos de ambos os sexos. Entre esses, 48 eram acompanhados no Ambulatório de Geriatria (AG) do Hospital de Clínicas da Faculdade de Ciências Médicas da UNICAMP. O outro grupo constituiu-se de 58 sujeitos do Grupo da Terceira Idade do Serviço Social do Comércio (SESC) de Campinas. Os instrumentos utilizados foram: ficha de avaliação de dados sócio-demográficos, prática de atividade física, doenças / estados mórbidos, número de medicamentos e fatores estressantes auto-relatados, bem como a percepção da qualidade de cada um dos ciclos de vida (infância, adolescência, idade adulta e velhice); International Neuropsychiatric Interview (MINI); questionário de qualidade de vida - WHOQOL-bref. Os resultados mostraram que a melhor percepção da qualidade de vida no domínio físico relacionou-se à prática de atividade física, ao não relato de dores, referência à boa infância e boa velhice, uso regular de menor quantidade de medicamentos. No domínio psicológico os idosos com melhor avaliação da qualidade de vida foram os que não apresentavam transtorno distímico, relatavam boa adolescência e velhice, usavam menor número de medicamentos e se consideravam felizes. No domínio social, a maior pontuação para qualidade de vida relacionou-se a: considerar-se feliz, não ter evidência de hipomania, negar solidão como evento estressante e referir boa adolescência. Quanto ao domínio ambiental, a referência à melhor qualidade de vida associou-se a: referir boa infância e velhice, maior nível de escolaridade e negar doença como evento estressante. Esses achados abrem para uma nova avaliação dos conceitos atuais sobre a velhice e processo de envelhecimento considerando-se os fatores que se associam a uma melhor percepção da qualidade de vida entre os idosos. Nesse estudo, verificou-se que a percepção da qualidade dos ciclos de vida, o uso de medicamentos, a prática de atividade física, a evidência de distimia e hipomania, o nível de escolaridade e a referência a dores, solidão e doença como eventos estressantes tinham interferência na percepção da qualidade de vida dos idosos avaliados
Abstract: Considering the relevance of life quality among aging individuals, this study has been developed with the aim to compare factors that interfere with the perception of lifequality (PLQ) between two distinct groups of elderly requiring the support of two different institutions. One hundred and six pacients have been assessed between ages sixty and eighty of both sexes. Among these, forty eight were followed closely by the Geriatric Ambulatory of the Hospital das Clínicas at the Faculty of Medical Sciences - UNICAMP. The other group consisted of fifty eight subjects from the group of elderly of the Serviço Social do Comércio (SESC) from Campinas. The instruments used were: a valuation card of sociodemographic data, ie, physical activity, diseases/morbid states, number of medicines taken, stress factors, as well as the perception of their life quality in each of the cycles of life, such as infancy, adolescence, adulthood and old age; The International Neuropsychiatric Interview (MINI); questionnaire on life quality - WHOQOL - BREF. The results showed that the best perception of quality of life in the physical domain were related to physical activity and absence of pain, a good activity and good age, regular minor use of medication. In the psychological area of the elderly, the best life quality valuation was of those who did not present distimic disorder, reported a happy adolescence and old age, used less medication, and considered themselves happy. In the social sphere the best valuation of life quality was related to considering oneself as happy, presenting an absence of hipomania, no stress on account of loneliness, a good adolescence. As for the environmental domain, the best quality of life was associated with a good childhood and old age, a higher level of education, no disease as stressful event. These findings lead to a new appraisal of the concepts on old age and the aging process, considering the possibilities associated with a better life quality for the elderly. In this study the perception of the life cycles'quality, the use of medication, physical activity, evidence of distimia and hipomania, level of education, reference to pains, solitude and disease as stressful events, interfered with the life quality of the valuated elderly
Doutorado
Saude Mental
Doutor em Ciências Médicas

Стилі APA, Harvard, Vancouver, ISO та ін.

Holmberg, Sara. "Musculoskeletal Disorders among Farmers and Referents, with Special Reference to Occurence, Health Care Utilization and Etiological Factors : A Population-based Study." Doctoral thesis, Uppsala University, Department of Public Health and Caring Sciences, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4626.

Повний текст джерела

Анотація:

Objectives. To study the prevalence of musculoskeletal symptoms among farmers as compared to rural referents and to evaluate the effects of physical work exposures, psychosocial factors, lifestyle and comorbidity.

Material and methods. A cross-sectional population-based survey of 1013 farmers and 769 matched referents was performed. Data on various symptoms, consultations and sick leave and information on primary health care and hospital admissions were obtained along with information on physical workload, psychosocial factors and lifestyle.

Results. The farmers reported higher lifetime prevalence of symptoms from hands and forearms, low back and hips as compared to the referents. However, the farmers did not seek medical advice more often than the referents, and they reported significantly fewer sick leaves. After adjustment for the influence of physical work exposure, farmers still had a excess rate of low back pain (LBP) and hip symptoms as compared with the referents, while a lower rate of neck-shoulder symptoms was revealed. Several of the psychosocial variables were associated with LBP but the difference in LBP prevalence between farmers and referents could only be explained to some extent. LBP was associated with musculoskeletal symptoms other than LBP and with chest discomfort, dyspepsia, symptoms from mucous membranes, skin problems, work-related fever attacks, and primary care for digestive disorders. Presence of both respiratory and digestive disorders doubled the LBP prevalence.

Conclusions. Symptoms from hips and low back were more frequent among farmers than among referents, but farmers did not seek more health care and reported fewer sick leaves than referents. Physical work exposure and psychosocial factors did not explain the differences in low back and hip symptoms between the two groups. Significant associations between LBP and digestive and respiratory disorders might indicate that these disorders may have etiological factors in common.

Стилі APA, Harvard, Vancouver, ISO та ін.

Книги з теми "Physical comorbidity"

Von Korff, Michael R., Kate M. Scott, and Oye Gureje, eds. Global Perspectives on Mental-Physical Comorbidity in the WHO World Mental Health Surveys. Cambridge: Cambridge University Press, 2009. http://dx.doi.org/10.1017/cbo9780511770531.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Michael, Von Korff, Scott Kate M. 1960-, and Gureje Oye, eds. Global perspectives on mental-physical comorbidity in the WHO World Mental Health Surveys. Cambridge: Cambridge University Press, 2009.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Michael, Von Korff, Scott Kate M, and Gureje Oye, eds. Global perspectives on mental-physical comorbidity in the WHO world mental health surveys. Cambridge: Cambridge University Press, 2009.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Michael, Von Korff, Scott Kate M. 1960-, and Gureje Oye, eds. Global perspectives on mental-physical comorbidity in the WHO World Mental Health Surveys. Cambridge: Cambridge University Press, 2009.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Psychological and physical co-morbidity: A behavioral medicine perspective. New York: Springer, 2011.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

J, Gordon Adam, ed. Physical illness and drugs of abuse: A review of the evidence. Cambridge: Cambridge University Press, 2010.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Rebecca, Perez, and Cohen Janice S, eds. The integrated case management manual: Assisting complex patients regain physical and mental health. New York: Springer, 2010.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Kolbasovsky, Andrew. A therapist's guide to understanding common medical conditions: Addressing a client's mental and physical health. New York: W.W. Norton, 2008.

Знайти повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Belik, Shay-Lee, Jitender Sareen, and Murray B. Stein. Anxiety Disorders and Physical Comorbidity. Oxford University Press, 2008. http://dx.doi.org/10.1093/oxfordhb/9780195307030.013.0046.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Sartorius, N., R. I. G. Holt, and M. Maj, eds. Comorbidity of Mental and Physical Disorders. S. Karger AG, 2014. http://dx.doi.org/10.1159/isbn.978-3-318-02604-7.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Більше джерел

Частини книг з теми "Physical comorbidity"

Murray, Hannah, and Sharif El-Leithy. "Physical comorbidity." In Working with Complexity in PTSD, 240–52. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003288329-26.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

El Aroussy, Nadia, and Yasser El Miedany. "Comorbidity and Physical Therapy." In Comorbidity in Rheumatic Diseases, 307–21. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59963-2_15.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Seeman, Mary V. "Psychosis and Physical Comorbidity." In Mental Health and Illness of Women, 1–28. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-10-0371-4_20-1.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Seeman, Mary V. "Psychosis and Physical Comorbidity." In Mental Health and Illness of Women, 231–58. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-10-2369-9_20.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Dalle Grave, Riccardo, Massimiliano Sartirana, and Simona Calugi. "Physical Complications." In Complex Cases and Comorbidity in Eating Disorders, 101–11. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-69341-1_7.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Kariuki-Nyuthe, Catherine, and Dan J. Stein. "Anxiety and Related Disorders and Physical Illness." In Comorbidity of Mental and Physical Disorders, 81–87. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000365538.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Hosman, Clemens. "Prevention of Comorbid Mental and Physical Disorders." In Comorbidity of Mental and Physical Disorders, 165–77. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000365601.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Gordon, Adam J., James W. Conley, and Joanne M. Gordon. "Physical Diseases and Addictive Disorders: Associations and Implications." In Comorbidity of Mental and Physical Disorders, 114–28. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000365543.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Fisher, Edwin B., Juliana C. N. Chan, Sarah Kowitt, Hairong Nan, Norman Sartorius, and Brian Oldenburg. "Conceptual Perspectives on the Co-Occurrence of Mental and Physical Disease: Diabetes and Depression as a Model." In Comorbidity of Mental and Physical Disorders, 1–14. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000365522.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Oldenburg, Brian, Adrienne O'Neil, and Fiona Cocker. "Public Health Perspectives on the Co-Occurrence of Non-Communicable Diseases and Common Mental Disorders." In Comorbidity of Mental and Physical Disorders, 15–22. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000365524.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Тези доповідей конференцій з теми "Physical comorbidity"

Abdollahyan, Maryam, Fabrizio Smeraldi, Rashmi Patel, and Conrad Bessant. "Investigating Comorbidity of Mental and Physical Disorders in Online Health Forums." In APPIS 2020: 3rd International Conference on Applications of Intelligent Systems. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3378184.3378195.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Mckevitt, S., C. Jinks, EL Healey, and JG Quicke. "RF26 The effectiveness of physical actvitiy interventions for people with osteoarthritis and comorbidity: a meta-analysis of obesity." In Society for Social Medicine 62nd Annual Scientific Meeting, Hosted by the MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, 5–7 September 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/jech-2018-ssmabstracts.114.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Lalo, Rezarta. "The Association between Social Integration, Coping Mechanisms and Anxiety in Patients with Non-Communicable Diseases." In World Lumen Congress 2021, May 26-30, 2021, Iasi, Romania. LUMEN Publishing House, 2022. http://dx.doi.org/10.18662/wlc2021/33.

Повний текст джерела

Анотація:

Recently, mental health issue and chronic physical condition are substantially linked and this comorbidity is likely to increase.Patient focusing in the self-care activities is an important component in the mechanism of coping with chronic disease with a significant impact on clinical and psychological outcomes. In this context, the current study is conducted to assess the impact of self-care and social integration mechanisms on anxiety levels among patients with chronic non-communicable diseases.This observational study of cross-sectional design was performed in the pathology service of Fier city hospital, in Albania during August-September 2020. To assess the level of anxiety, we used the scale of 7 items of General Anxiety Disorder (GAD-7) with a score of ≥10 indicating GAD. Subscales of the Health Education Impact Questionnaire (heiQ) were used in order to evaluate social integration and self-care mechanism. The data were entered into the statistical program SPSS, version 23. The regression analysis is performedto examine the relationship between variables. The findings revealed that 56% of participants had GAD, 47% of participants were unable to self-monitor the disease, while 89% of them didnot performe any type of physical activity. The scale of anxiety was significantly associated with variables of Self–monitoring (p=0.000<0.05; OR=0.10) and Social integration (p=0.000<0.05; OR=21.4). These findings address the need to support peoplewho struggle with chronic non-communicable diseases developing adaptive ways to deal with their chronic condition and improve their lifestyle for better overall health.

Стилі APA, Harvard, Vancouver, ISO та ін.

Ghandeharioun, Hosna. "Online Obstructive Sleep Apnea Detection Based on Hybrid Machine Learning and Classifier Combination for Home-Based Applications." In 3rd International Conference on Machine Learning & Applications (CMLA 2021). Academy and Industry Research Collaboration Center (AIRCC), 2021. http://dx.doi.org/10.5121/csit.2021.111503.

Повний текст джерела

Анотація:

Automatic detection of obstructive sleep apnea (OSA) is in great demand. OSA is one of the most prevalent diseases of the current century and established comorbidity to Covid-19. OSA is characterized by complete or relative breathing pauses during sleep. According to medical observations, if OSA remained unrecognized and un-treated, it may lead to physical and mental complications. The gold standard of scoring OSA severity is the time-consuming and expensive method of polysomnography (PSG). The idea of online home-based surveillance of OSA is welcome. It serves as an effective way for spurred detection and reference of patients to sleep clinics. In addition, it can perform automatic control of the therapeutic/assistive devices. In this paper, several configurations for online OSA detection are proposed. The best configuration uses both ECG and SpO2 signals for feature extraction and MI analysis for feature reduction. Various methods of supervised machine learning are exploited for classification. Finally, to reach the best result, the most successful classifiers in sensitivity and specificity are combined in groups of three members with four different combination methods. The proposed method has advantages like limited use of biological signals, automatic detection, online working scheme, and uniform and acceptable performance (over 85%) in all the employed databases. These advantages have not been integrated in previous published methods.

Стилі APA, Harvard, Vancouver, ISO та ін.

Vihar, Jangala Sai, and Deepak Mulajker. "A Descriptive Study to Assess the Association of Geriatric Score with Observed Chemo Toxicity in Cancer Patients Older than 60 Years." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735373.

Повний текст джерела

Анотація:

Abstract Introduction Cancer is the leading cause of death worldwide with elderly patients being predominantly affected. There seems to be a bias against administering chemotherapy to elderly patients with fewer elderly patients receiving chemotherapy as compared with their stagematched younger patients because of concerns about their capacity to endure treatment. To make personalized treatment decisions and to anticipate serious adverse effects, a toxicity prediction tool that can be computed at the bedside is the need of the hour. This well-validated score has not been tested in the Indian population. So, we decided to test the same score in our patients and try to correlate the score with the observed toxicity. Objectives This study was aimed to determine geriatric functional status by means of a standardized geriatric score and to correlate geriatric score with observed chemo toxicity. Materials and Methods Fifty consecutive elderly patients (age > 60 years) with a diagnosis of cancer and scheduled for chemotherapy were recruited. These patients were evaluated using the geriatric assessment tool which is based on functional, nutritional, and psychological status. After that patient’s pretherapy, chemo toxicity score or geriatric score was calculated using a published well-validated tool that consisted of 11 prechemotherapy variables as follows:a) Age of patient,b) Cancer typec) Planned chemotherapy dose,d) Planned number of chemotherapy drugse) Hemoglobin,f) Creatinine clearanceg) Geriatric questions like -i. How is your hearing?ii. Number of falls in past 6 months?iii. Can take your own medicines?iv. Does your health limit you in walking one block ? during past 4 weeksv. How much of time has your physical health or emotional problems interfered with your social activities (like visiting with friends, relatives etc.)The patients were then followed from the beginning to the end of six cycles of their chemotherapy regimen. Toxicities were noted after each clinical encounter by using the NCI-CTCAE, version 3.0.25. Results General characteristics: the mean age of participants was 66 years (standard deviation [SD] = 4.6 and range: 60–85 years). Of them, 60% received polychemotherapy and 82% received standard doses of chemotherapy. The mean score on activities of daily living was 66.7, comorbidity score was 2.7, the psychological scale was 63.8, the social-activity scale was 54.3, and social-support scale was 64.1. The mean pretherapy toxicity score is 7.24 according to the toxicity calculator. At least one grade 3 to 5 toxicity occurred in 30% of the patients (66% of grade 3, 20% of grade 4, and 13.3% of grade 5). The correlation between the predicted score and observed graded toxicity score by Pearson’s scale (α = 0.05) was 0.63. Conclusion The prediction model is easy to use, thus increasing the feasibility of incorporation in daily practice is important. It may enable oncologists to better assess the risk/benefit ratio and to adjust the treatment accordingly.

Стилі APA, Harvard, Vancouver, ISO та ін.

Звіти організацій з теми "Physical comorbidity"

Li, Yinhua, Wanting Lan, and Xiaohui Hou. The effectiveness of physical activities on children with autism spectrum disorder: A systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0034.

Повний текст джерела

Анотація:

Review question / Objective: The purpose of this meta-analysis was to evaluate the efficacy of different physical activity interventions and to determine which physical activity interventions are most effective for children with autism spectrum disorder. Condition being studied: Autism is a set of heterogeneous neurodevelopmental conditions, characterized by early-onset difficulties in social communication and unusually restricted, repetitive behavior and interests. Autism affects more male than female individuals, and comorbidity is common (>70% have concurrent conditions). Exercise has increasingly emerged as one of the promising compensation methods that can positively affect autistic symptoms. The positive effects of various physical activity interventions have been reported, but it is unclear which interventions are most effective at improving symptoms of autism.

Стилі APA, Harvard, Vancouver, ISO та ін.

Ми пропонуємо знижки на всі преміум-плани для авторів, чиї праці увійшли до тематичних добірок літератури. Зв'яжіться з нами, щоб отримати унікальний промокод!