Добірка наукової літератури з теми "Pharmacokinetics"
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Статті в журналах з теми "Pharmacokinetics"
Iorio, Alfonso. "Using pharmacokinetics to individualize hemophilia therapy." Hematology 2017, no. 1 (December 8, 2017): 595–604. http://dx.doi.org/10.1182/asheducation-2017.1.595.
Повний текст джерелаKamp, Jasper, Erik Olofsen, Thomas K. Henthorn, Monique van Velzen, Marieke Niesters, and Albert Dahan. "Ketamine Pharmacokinetics." Anesthesiology 133, no. 6 (September 30, 2020): 1192–213. http://dx.doi.org/10.1097/aln.0000000000003577.
Повний текст джерелаJeong, Seung-Hyun, Ji-Hun Jang, and Yong-Bok Lee. "Pharmacokinetic Comparison between Methotrexate-Loaded Nanoparticles and Nanoemulsions as Hard- and Soft-Type Nanoformulations: A Population Pharmacokinetic Modeling Approach." Pharmaceutics 13, no. 7 (July 9, 2021): 1050. http://dx.doi.org/10.3390/pharmaceutics13071050.
Повний текст джерелаGrzegorzewski, Jan, Janosch Brandhorst, Kathleen Green, Dimitra Eleftheriadou, Yannick Duport, Florian Barthorscht, Adrian Köller, Danny Yu Jia Ke, Sara De Angelis, and Matthias König. "PK-DB: pharmacokinetics database for individualized and stratified computational modeling." Nucleic Acids Research 49, no. D1 (November 5, 2020): D1358—D1364. http://dx.doi.org/10.1093/nar/gkaa990.
Повний текст джерелаAlbitar, Orwa, Sabariah Noor Harun, Hadzliana Zainal, Baharudin Ibrahim, and Siti Maisharah Sheikh Ghadzi. "Population Pharmacokinetics of Clozapine: A Systematic Review." BioMed Research International 2020 (January 8, 2020): 1–10. http://dx.doi.org/10.1155/2020/9872936.
Повний текст джерелаTang, Bo-Hao, Yue-E. Wu, Chen Kou, Yu-Jie Qi, Hui Qi, Hai-Yan Xu, Stephanie Leroux, et al. "Population Pharmacokinetics and Dosing Optimization of Amoxicillin in Neonates and Young Infants." Antimicrobial Agents and Chemotherapy 63, no. 2 (December 3, 2018): e02336-18. http://dx.doi.org/10.1128/aac.02336-18.
Повний текст джерелаEgan, Talmage D., Bernou Huizinga, Samir K. Gupta, Rudy L. Jaarsma, Richard J. Sperry, James B. Yee, and Keith T. Muir. "Remifentanil Pharmacokinetics in Obese versus Lean Patients." Anesthesiology 89, no. 3 (September 1, 1998): 562–73. http://dx.doi.org/10.1097/00000542-199809000-00004.
Повний текст джерелаStepensky, David. "Pharmacokinetics of Toxin-Derived Peptide Drugs." Toxins 10, no. 11 (November 20, 2018): 483. http://dx.doi.org/10.3390/toxins10110483.
Повний текст джерелаLi, Qiao, Yan Yang, Ting Zhou, Rui Wang, Na Li, Min Zheng, Yuan-Yuan Li, et al. "A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples." Molecules 23, no. 8 (August 15, 2018): 2042. http://dx.doi.org/10.3390/molecules23082042.
Повний текст джерелаToja-Camba, Francisco José, Nerea Gesto-Antelo, Olalla Maroñas, Eduardo Echarri Arrieta, Irene Zarra-Ferro, Miguel González-Barcia, Enrique Bandín-Vilar, et al. "Review of Pharmacokinetics and Pharmacogenetics in Atypical Long-Acting Injectable Antipsychotics." Pharmaceutics 13, no. 7 (June 23, 2021): 935. http://dx.doi.org/10.3390/pharmaceutics13070935.
Повний текст джерелаДисертації з теми "Pharmacokinetics"
Chigutsa, Emmanuel. "Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs." Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3275.
Повний текст джерелаIncludes bibliographical references.
The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in 78 patients with tuberculosis were described using non-linear mixed effects modeling. Pharmacodynamic data was comprised of weekly sputum liquid culture (using mycobacterial growth indicator tubes) time to detection results from 144 patients during the first 2 months of treatment. The effect of drug exposure on patient outcomes was investigated. To determine the adequacy of ofloxacin drug exposure, the probability of attaining the required area-under-the-curve to minimum inhibitory concentration ratio (AUC/MIC) of ofloxacin was determined in 65 patients on treatment for multidrug resistant tuberculosis. To improve efficiency in the clinical development of new drug regimens, clinical trial simulation was used to determine the optimal study design for a study investigating the efficacy of a new antitubercular drug regimen. The SLCO1B1 rs4149032 polymorphism existed at a high frequency of 0.70 in South Africans and resulted in a 28% decrease in bioavailability of rifampicin. The rifampicin peak concentration was a significant predictor of the 2 month treatment outcomes. A semimechanistic time to event model was developed to analyze days to positivity (time to detection) data. The model was comprised of a biexponential decay model describing bacillary decline in sputum from patients, followed by a logistic model with a lag time for growth of the mycobacteria in liquid culture. For the current 800 mg daily dose of ofloxacin, the probability of attaining an AUC/MIC target ratio of at least 100 was only 0.45. Based on clinical trial simulation, the optimum parallel study design was comprised of 125 study participants in each of 2 arms to achieve a study power of at least 80%. Increasing the study length beyond 42 days reduced study power perhaps due to increased amounts of censored data. Higher doses of rifampicin are required in the majority of South African patients with tuberculosis. A novel pharmacodynamic model of tuberculosis treatment is presented, which can be used for investigation of covariates such as drug exposure. Ofloxacin should be replaced with a more potent fluoroquinolone for treatment of multidrug resistant tuberculosis. Clinical trials should not be unduly long otherwise this may compromise study power.
Ulrich-Oppliger, Brigitte Madeleine. "Pharmacokinetics /." Bern, 1992. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Повний текст джерелаCharter, Mark Keith. "Maximum entropy pharmacokinetics." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316691.
Повний текст джерелаSmith, Jennifer Lisa. "Pharmacokinetics of methylamines." Thesis, Massachusetts Institute of Technology, 1992. http://hdl.handle.net/1721.1/12906.
Повний текст джерелаKhosravan, Reza. "Nonlinear pharmacokinetics of diltiazem." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0030/NQ46865.pdf.
Повний текст джерелаAl-Mustafa, Z. H. "Methotrexate pharmacokinetics and toxicity." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383988.
Повний текст джерелаWoodhouse, Jennifer Ann. "Plutonium pharmacokinetics and blood biochemistry." Thesis, University of Central Lancashire, 1997. http://clok.uclan.ac.uk/20148/.
Повний текст джерелаSmith, Adam John. "Modulating the Pharmacokinetics of Bioflavonoids." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4226.
Повний текст джерелаHarper, Kenneth W. "Pharmacokinetics of methohexitone and midazolam." Thesis, Queen's University Belfast, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254195.
Повний текст джерелаEvans, Gary Lee. "Pharmacokinetics and metabolism of lacidipine." Thesis, University of Hertfordshire, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387196.
Повний текст джерелаКниги з теми "Pharmacokinetics"
Pecile, A., and A. Rescigno, eds. Pharmacokinetics. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5.
Повний текст джерелаRiviere, Jim E. Comparative pharmacokinetics. Chichester, West Sussex: Wiley-Blackwell, 2011.
Знайти повний текст джерелаKrishna, Devarakonda Rama, and Ulrich Klotz. Clinical Pharmacokinetics. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75623-8.
Повний текст джерелаRiviere, Jim E. Comparative Pharmacokinetics. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9780470959916.
Повний текст джерелаDavies, Neal M., and Jaime A. Yáñez, eds. FLAVONOID PHARMACOKINETICS. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118468524.
Повний текст джерелаWu, Baojian, Danyi Lu, and Dong Dong, eds. Circadian Pharmacokinetics. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8807-5.
Повний текст джерелаJ, Breen Philip, ed. Basic pharmacokinetics. London: Pharmaceutical Press, 2009.
Знайти повний текст джерела1943-, Shroot B., Schaefer H. 1935-, and Centre international de recherches dermatologiques., eds. Skin pharmacokinetics. Basel: Karger, 1987.
Знайти повний текст джерелаKällén, Anders. Computational pharmacokinetics. Boca Raton, FL: Chapman & Hall/CRC, 2008.
Знайти повний текст джерелаKällén, Anders. Computational pharmacokinetics. Boca Raton: Taylor & Francis, 2007.
Знайти повний текст джерелаЧастини книг з теми "Pharmacokinetics"
Gladtke, Erich. "History of Pharmacokinetics." In Pharmacokinetics, 1–9. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_1.
Повний текст джерелаMetzler, Carl M. "Equivalence of Bioavailability and Efficacy in Drug Testing." In Pharmacokinetics, 215–25. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_10.
Повний текст джерелаThakur, Ajit K. "Modeling and Risk Assessment of Carcinogenic Dose-Response." In Pharmacokinetics, 227–44. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_11.
Повний текст джерелаBass, Ludvik, and Susan M. Pond. "The Puzzle of Rates of Cellular Uptake of Protein-Bound Ligands." In Pharmacokinetics, 245–69. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_12.
Повний текст джерелаMordenti, Joyce. "A Pharmacokinetic Equation Guide for Clinicians." In Pharmacokinetics, 271–89. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_13.
Повний текст джерелаWagner, John G. "Pharmacokinetic Studies in Man." In Pharmacokinetics, 291–322. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_14.
Повний текст джерелаBreuer, Francesco. "Metabolic Models in Radiation Protection." In Pharmacokinetics, 323–35. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_15.
Повний текст джерелаBeck, James S. "Conceptual Foundations and Uses of Models in Pharmacokinetics." In Pharmacokinetics, 11–18. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_2.
Повний текст джерелаRescigno, Aldo, and Ajit K. Thakur. "Development of Compartmental Concepts." In Pharmacokinetics, 19–26. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_3.
Повний текст джерелаThakur, Ajit K. "Modeling of Pharmacokinetic Data." In Pharmacokinetics, 27–59. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5463-5_4.
Повний текст джерелаТези доповідей конференцій з теми "Pharmacokinetics"
Dol, F., G. Houin, D. Dupouy, C. Caranobe, Y. Cadroy, P. Sié, and B. Boneu. "THE PHARMACOKINETICS OF 125-I DERMATAN SULFATE IN THE RABBIT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643243.
Повний текст джерелаEvans, Conor L. "Quantifying human cutaneous pharmacokinetics." In Advanced Chemical Microscopy for Life Science and Translational Medicine 2021, edited by Garth J. Simpson, Ji-Xin Cheng, and Wei Min. SPIE, 2021. http://dx.doi.org/10.1117/12.2577713.
Повний текст джерелаJohansson, Ann, Jenny Svensson, Stefan Andersson-Engels, Niels Bendsoe, Katarina Svanberg, Irving Bigio, Eleni Alexandratou, et al. "mTHPC pharmacokinetics following topical administration." In Biomedical Optics 2006, edited by Gerard L. Coté and Alexander V. Priezzhev. SPIE, 2006. http://dx.doi.org/10.1117/12.647602.
Повний текст джерелаCaranobe, C., G. Houin, C. Picard, J. M. Pereillo, and B. Boneu. "THE PHARMACOKINETICS OF 125I PENTOSAN POLYSULFATE IN THE RABBIT : EVIDENCE FOR A SATURABLE MECHANISM OF CLEARANCE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643248.
Повний текст джерелаKasyanova, V. V., and I. N. Bazhukova. "Modeling of cerium oxide nanoparticles pharmacokinetics." In THE 2ND INTERNATIONAL CONFERENCE ON PHYSICAL INSTRUMENTATION AND ADVANCED MATERIALS 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0032208.
Повний текст джерелаLee, Seok-Yong, Chang-Keun Cho, Pureum Kang, Eunvin Ko, and Chou Yen Mu. "Physiologically Based Pharmacokinetic (PBPK) Modeling to Predict the Pharmacokinetics of Irbesartan in DifferentCYP2C9Genotypes." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.508580.
Повний текст джерелаAhmed, Nusrat, Yashpal S. Chhonker, Valentina Shakhnovich, Veronica Williams, and Daryl J. Murry. "Development of a Physiologically Based Pharmacokinetic Model for Predicting Midazolam Pharmacokinetics in a Pediatric Population with Obesity." In ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.404.938920.
Повний текст джерелаKeith, Godfrey,. "Modelling the Double Peak Phenomenon in Pharmacokinetics." In Modeling and Control in Biomedical Systems, edited by Rees, Stephen, Chair Andreassen, Steen and Andreassen, Steen. Elsevier, 2009. http://dx.doi.org/10.3182/20090812-3-dk-2006.00022.
Повний текст джерелаFeizpour, Amin, Louise Bastholm, Troels T. Marstrand, and Conor L. Evans. "Label-free Quantification of Pharmacokinetics in Skin." In Bio-Optics: Design and Application. Washington, D.C.: OSA, 2019. http://dx.doi.org/10.1364/boda.2019.jw3c.1.
Повний текст джерелаHovanessian, Vladimir A., Asatour Lalaian, and Grigor Gyulkhandanyan. "Laser fluorescence investigation of chlorin e6 pharmacokinetics." In BiOS Europe '96, edited by Stanley B. Brown, Benjamin Ehrenberg, and Johan Moan. SPIE, 1996. http://dx.doi.org/10.1117/12.260784.
Повний текст джерелаЗвіти організацій з теми "Pharmacokinetics"
Hawkins, David R. Determination of Drug Pharmacokinetics and Metabolic Profile. Volume 2. Fort Belvoir, VA: Defense Technical Information Center, March 1988. http://dx.doi.org/10.21236/ada192428.
Повний текст джерелаHeinen, Jessica. Process of Modeling Pharmacokinetics Using Nonlinear Mixed-Effect Models. Ames (Iowa): Iowa State University, January 2020. http://dx.doi.org/10.31274/cc-20240624-1156.
Повний текст джерелаGurley, L. R., K. O. Umbarger, J. M. Kim, E. M. Bradbury, and B. E. Lehnert. Staurosporine analysis and its pharmacokinetics in the blood of rats. Office of Scientific and Technical Information (OSTI), July 1994. http://dx.doi.org/10.2172/10160825.
Повний текст джерелаCheung, Nai-Kong V., Shakeel Modak, Yukang Lin, Hongfen Guo, Pat Zanzonico, John Chung, Yuting Zuo, et al. Pharmacokinetics of Genetically Engineered Antibody Forms Using Positron Emission Tomography. Office of Scientific and Technical Information (OSTI), August 2004. http://dx.doi.org/10.2172/828873.
Повний текст джерелаKarna, Shravya, and Alex Konstantatos. Methadone and Buprenorphine for Management of Acute Postoperative Pain. World Federation of Societies of Anaesthesiologists, May 2022. http://dx.doi.org/10.28923/atotw.472.
Повний текст джерелаKamimori, Gary H. Effect of Time of Menstrual Cycle on Drug Pharmacokinetics and Pharmacodynamics. Fort Belvoir, VA: Defense Technical Information Center, May 2001. http://dx.doi.org/10.21236/ada409105.
Повний текст джерелаKornhauser, David M., Brent G. Petty, and Paul S. Lietman. Pharmacokinetics and Pharmacodynamics of Sustained Low-Dose Intravenous Infusions of Pyridostigmine. Fort Belvoir, VA: Defense Technical Information Center, May 1993. http://dx.doi.org/10.21236/ada530411.
Повний текст джерелаCarpenter, Hillary M., and Lawrence R. Curtis. Pharmacokinetics of Lipophilic Agents Following Preexposure: Non-Cytochrome P-450 Mediated Mechanisms. Fort Belvoir, VA: Defense Technical Information Center, May 1990. http://dx.doi.org/10.21236/ada225356.
Повний текст джерелаGorden, Patrick J., Michael D. Kleinhenz, Larry W. Wulf, Butch KuKanich, Chang J. Lee, Chong Wang, and Johann F. Coetzee. Altered Plasma Pharmacokinetics of Ceftiofur Hydrochloride in Cows Affected with Severe Clinical Mastitis. Ames (Iowa): Iowa State University, January 2016. http://dx.doi.org/10.31274/ans_air-180814-216.
Повний текст джерелаLi, Haobo, Zhu Zhang, Haoyi Weng, Yuting Qiu, Pablo Zubiaur, Yu Zhang, Guohui Fan, et al. Association of rs2244613 Polymorphism with Dabigatran Pharmacokinetics and Safety: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0027.
Повний текст джерела