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Статті в журналах з теми "Phage library"
Farquharson, Emma L., and Sam R. Nugen. "Enterobacteria Phage Ac3's Genome Annotation and Host Range Analysis Against the ECOR Reference Library." PHAGE 3, no. 3 (September 1, 2022): 165–70. http://dx.doi.org/10.1089/phage.2022.0008.
Повний текст джерелаPetrenko, V. A., G. P. Smith, M. M. Mazooji та T. Quinn. "α-Helically constrained phage display library". Protein Engineering, Design and Selection 15, № 11 (листопад 2002): 943–50. http://dx.doi.org/10.1093/protein/15.11.943.
Повний текст джерелаSaggio, I., and R. Laufer. "Biotin binders selected from a random peptide library expressed on phage." Biochemical Journal 293, no. 3 (August 1, 1993): 613–16. http://dx.doi.org/10.1042/bj2930613.
Повний текст джерелаWen, Jianxin, and Kunpeng Yuan. "Phage Display Technology, Phage Display System, Antibody Library, Prospects and Challenges." Advances in Microbiology 11, no. 03 (2021): 181–89. http://dx.doi.org/10.4236/aim.2021.113013.
Повний текст джерелаDing, Yan-Li, Mei-Yun Liu, Wei Han, Sheng-Li Yang, Hui Liu, and Yi Gong. "Application of Phage-displayed Single Chain Antibodies in Western Blot." Acta Biochimica et Biophysica Sinica 37, no. 3 (March 1, 2005): 205–9. http://dx.doi.org/10.1093/abbs/37.3.205.
Повний текст джерелаGillespie, James W., Liping Yang, Laura Maria De Plano, Murray A. Stackhouse, and Valery A. Petrenko. "Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer." Viruses 11, no. 11 (October 26, 2019): 988. http://dx.doi.org/10.3390/v11110988.
Повний текст джерелаBrichta, J., H. Vesela, and M. Franek. "Production of scFv recombinant fragments against 2,4-dichlorophenoxyacetic acid hapten using naďve phage library." Veterinární Medicína 48, No. 9 (March 30, 2012): 237–47. http://dx.doi.org/10.17221/5776-vetmed.
Повний текст джерелаDaniele, Sblattero, Not Tarcisio, Marzari Roberto, and Bradbury Andrew. "PHAGE ANTIBODY LIBRARY FROM CELIAC DISEASE PATIENT." Journal of Pediatric Gastroenterology & Nutrition 28, no. 5 (May 1999): 568. http://dx.doi.org/10.1097/00005176-199905000-00118.
Повний текст джерелаBarchan, D., M. Balass, M. C. Souroujon, E. Katchalski-Katzir, and S. Fuchs. "Identification of epitopes within a highly immunogenic region of acetylcholine receptor by a phage epitope library." Journal of Immunology 155, no. 9 (November 1, 1995): 4264–69. http://dx.doi.org/10.4049/jimmunol.155.9.4264.
Повний текст джерелаDuplessis, Martin, Céline M. Lévesque, and Sylvain Moineau. "Characterization of Streptococcus thermophilus Host Range Phage Mutants." Applied and Environmental Microbiology 72, no. 4 (April 2006): 3036–41. http://dx.doi.org/10.1128/aem.72.4.3036-3041.2006.
Повний текст джерелаДисертації з теми "Phage library"
Bell, Matthew John. "Phage display of a cDNA library from Arabidopsis thaliana." Thesis, Coventry University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393652.
Повний текст джерелаKeklikian, Artine. "Construction of a Synthetic Human VL Phage Display Library and Isolation of Potential Neuropilin-1-specific VL Therapeutics from the Library." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20197.
Повний текст джерелаClayton, Ruth. "Generation and characterisation of human sperm antibodies by combinatorial phage display library technology." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286988.
Повний текст джерелаHald, Rikke. "Generation and characterisation of a naive human antibody phage display library : a resource for clinically relevant reagents /." Cph. : Department of Pharmacology, The Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/rikkehald.htm.
Повний текст джерелаPrendergast, D. "Discovery of tumour necrosis factor receptor-1 (p55) binding peptides using a phage display library." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368468.
Повний текст джерелаSaxena, Abhishek. "Construction of immune scFv M13 phage display library and isolation of anti-glycan monoclonal antibodies." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=203295.
Повний текст джерелаLim, Theam Soon [Verfasser]. "Parameters affecting phage display library design for improved generation of human antibodies / Theam Soon Lim." Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023748355/34.
Повний текст джерелаCortini, Andrea. "Serum profiling and autoantibodies identification in Multiple Sclerosis using epitope and CSF IgG phage display libraries." Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3073.
Повний текст джерелаMultiple sclerosis (MS) is considered the prototype of inflammatory autoimmune diseases of the central nervous system (CNS). The typical feature of the disease is the plaques of demyelination. The evolution of the plaque lesion in MS implicates an inflammatory phase followed by a recovery of functional myelin; a second step is the chronic progressive disease with axonal loss. The earlier phase of MS may be mediated by an autoimmune reaction. Whereas the role of T cells in MS pathogenesis is well established, the role of B cells and autoantibodies in demyelination and plaque formation is still unresolved. However several evidences suggest a contribute of autoantibodies in MS pathogenesis. B cells and myelin specific autoantibodies are present in the sclerosis plaques, and there is an increased production of immunoglobulin (Ig) in the cerebrospinal fluid (CSF) of more than 90% of MS patients . Typically these Ig present an oligoclonal pattern and sequencing of oligoclonal IgG showed extensive somatic mutations suggesting B cell clonal expansion and a specific antigen-driven immune response. The most extensively studied putative autoantigens are components of CNS myelin (myelin basic protein MBP, proteolipid protein PLP, myelin oligodendrocyte glycoprotein MOG). The autoantibodies in MS recognize both linear and conformational epitopes, but at present the conformational epitopes of myelin proteins have not been identified. For example, in MS, the T-cell receptors of autoreactive T lymphocytes recognize various peptides of the MBP, and, in EAE, the anti-MOG antibodies recognize only conformational epitopes. Furthermore, the progression of MS is accompanied by the decline of primary T-cell autoreactivity and by the concurrent emergence of neo-autoreactivity (epitope spreading). However recent investigation have showed that no myelin antigens, like neuron-specific enolase (NSE), retinal arrestin, beta-arrestin, may also have a role in MS pathogenesis. Autoimmunity against these antigens may be linked to neurodegeneration, defective remyelination, and predisposition to uveitis in multiple sclerosis. Several strategies, involving the phage display technology, have been employed in the attempt to discover the antigen that drives the immune response in MS. A first strategy depends on the cloning of IgG repertoire of MS patients in a phage display library screened with brain sections or known antigens. Another strategy involves large phage display libraries of random peptides screened with IgG of CSF in order to identify peptides recognized by antibodies present in CSF of MS patients. Phage display is a technique which involves the coupling of phenotype to genotype in a selectable format. It has been extensively used in molecular biology to study protein-protein interactions and to select antibodies against a wide range of different antigens. In this project we have proposed: 1. to study the autoimmune response in MS by using the phage display for the expression of antibodies involved in the disease. We wanted to make a ScFv library from B cells of CSF of different multiple sclerosis patients, to employ as tool to select a phage display Human Brain cDNA library for the identification of new antigens recognized by the immune sistem in MS patients. 2. To produce single gene mini library of putative antigens (MBP,PLP, MOG) for the generation of epitope chips to use for serotyping the immune response in different patients 3. To investigate the feasibility to use a single gene phage display mini-library as tool for epitope mapping (both linear and conformational) of novels autoantigens 4. To investigate the role of NSE(neuron specific enolase), a new possible no myelin autoantigen in multiple sclerosis, in the pathogenesis of the disease and the usefulness as possible diagnostic marker. Results: Scope 1 B-cells from liquor of two MS patients were centrifuged and the total RNA was extracted from the pellets. Total RNA was retrotranscripted and variable region of heavy and light chain of the antibodies were amplified by PCR. Heavy chain and light chain were assorted and assembled before to be cloned in the phagemid vector pDAN 5. A 2x104 independent clones library was obtained and analyzed by PCR and fingerprinting. A diversity of 30,8% for heavy chain and 72,7% for light chain was established. ScFv library was used to select a phage display Human Brain cDNA library. 17 clones with an high reactivity were obtained and after sequencing 6 clones on 17 have shown to be the same antigen(antigen A ); the reactivity on other two antigens obtained with the selection (antigen B and C) of CSF from 18 MS patients and 16 patients with other neurological disease (OND) was tested by ELISA to evaluate diagnostic value of this protein. The results shown that SM response was statistically different from OND response; the ELISA test gave a specificity of 94,12% and a significance of 53,85 %. The reactivity for the antigen B was also evaluated on sera of MS patients and controls. The MS response was statistically different from OND response and shown a specificity of 97,44% and a significance of 58,62 %. Scope 2&3 We have generated three single gene mini libraries of the major antigens in MS (MBP, MOG and PLP); cDNA of each gene was obtained by RT-PCR and after fragmentation cloned in a phagemid vector (pEP1) to obtain a mini-library for each gene. We have obtained a 2x105 for MBP, 2.4x104 for MOG and 1.6x106 for PLP independent clones library. MBP and MOG libraries were characterized by PCR and fingerprinting. Sequencing analysis shown that the entire MBP transcript variant 7 mRNA (664-1177 nt) and MOG isoform alpha 1 mRNA (262-918 nt) were represented in the respective library. To testing the capacity of selecting a single epitope from our libraries, we have performed a selection test with a commercial monoclonal antibody that recognize MBP 82-98 epitope; after three selection panning all selected clones contain the nucleotidic sequence 906- 956 nt (MBP transcript variant 7 mRNA) which encodes the immunogenic epitope recognized by the monoclonal antibody. Scope 4 The reactivity of sera from 31 MS patients and 14 healthy controls was tested by ELISA on NSE ; statistical analysis of the results shown that the two populations were significantly different.
XXI Ciclo
1981
Bosompem, Amma N. "Isolation of an anti-CD20 single chain variable fragment from a naïve human phage-scFv library." Connect to this title online, 2007. http://etd.lib.clemson.edu/documents/1202410076/.
Повний текст джерелаMarson, Lorena. "Phage-display epitope library development for biomarkers identification in autoimmune diseases of the Central Nervous System." Doctoral thesis, Università degli studi di Trieste, 2012. http://hdl.handle.net/10077/7405.
Повний текст джерелаThe principal aim of my PhD was the setting of a protocol for the creation of phage libraries to display cDNA fragments encoding real ORF sequences, that could correspond to potential epitopes. A similar phage display library contains all the potential ORF repertoire of a cell or tissue. This tool can be specially used in the study of autoimmune diseases to perform different kind of analysis, such as the identification of epitopes involved in pathological reaction, the comparison between healthy and pathological conditions, or between different pathological conditions. A complex protocol was developed. It provides for: cDNA normalization, cDNA fragmentation to obtain peptides with useful size, and ORF enrichment to obtain really coding fragments. With this system we have created a epitopes library from Human brain mRNA.
Il principale obiettivo del mio lavoro di ricerca è la messa a punto di un protocollo per la costruzione di librerie fagiche di frammenti di cDNA codificanti per frammenti ORF, e che quindi potrebbero corrispondere a potenziali epitopi. Questo tipo di librerie contengono, potenzialmente, tutto il repertorio ORF di una cellula o di un tessuto e possono quindi essere utilizzate nello studio di malattie autoimmuni al fine di identificare nuovi epitopi coinvolti nella risposta immunitaria, di fare un confronto tra lo stato patologico e quello sano o tra diverse condizioni patologiche. Abbiamo quindi messo a punto un complesso protocollo che prevede: la normalizzazione del cDNA, la sua frammentazione per ottenere peptidi di dimensioni opportune, e l'arricchimento in frammenti realmente codificanti. Con questo sistema abbiamo realizzato una libreria di epitopi a partire da mRNA di cervello umano.
XXIV Ciclo
1984
Книги з теми "Phage library"
Tim, Clackson, and Lowman Henry B, eds. Phage display: A practical approach. Oxford: Oxford University Press, 2004.
Знайти повний текст джерелаClarke, Dougan & Associates. Library automation study: Feasibility phase : final report. [Waterloo, Ont.]: Clarke, Dougan & Associates, 1987.
Знайти повний текст джерелаBeaumont, Jane. Bancroft Public Library: Needs assessment for library automation, APSL phase I report. [Bancroft, Ont.]: The Library, 1987.
Знайти повний текст джерелаConsultants, Woods Gordon Management. Barrie Public Library facilities development study, phase II. [Toronto: Woods Gordon, 1989.
Знайти повний текст джерелаCrawford, Walt. Patron Access Project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Знайти повний текст джерелаCrawford, Walt. Patron Access Project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Знайти повний текст джерелаResearch Libraries Group. Research & Development Division., ed. Patron access project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Знайти повний текст джерелаAssociates, Fox Jones &. Wainfleet Township Public Library facility feasibility study: Phase II report. [Wainfleet, Ont: Wainfleet Township Public Library, 1991.
Знайти повний текст джерелаFox Jones & Associates. Wainfleet Township Public Library needs assessment study: Phase I report. [Wainfleet, Ont: WTPL, 1990.
Знайти повний текст джерелаLibrary, Fort Erie Public, and Information Technology Strategy Inc, eds. Fort Erie Public Library automation feasibility study: Phase 1 report. [Toronto, Ont: Information Technology Strategy Inc., 1988.
Знайти повний текст джерелаЧастини книг з теми "Phage library"
Midoro-Horiuti, Terumi, and Randall M. Goldblum. "Epitope Mapping with Random Phage Display Library." In Methods in Molecular Biology, 477–84. Totowa, NJ: Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-992-5_28.
Повний текст джерелаWeil, Clifford F., and Thomas E. Bureau. "Construction of a Genomic Library in Lambda Phage." In The Maize Handbook, 595–98. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2694-9_105.
Повний текст джерелаFagerlund, Annette, Astrid Hilde Myrset, and Mari Ann Kulseth. "Construction of a Filamentous Phage Display Peptide Library." In Methods in Molecular Biology, 19–33. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-673-3_2.
Повний текст джерелаSamoylova, Tatiana I., and Bruce F. Smith. "Identification of Cell Targeting Ligands Using Random Peptide-Presenting Phage Libraries." In Genetic Library Construction and Screening, 209–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56408-6_11.
Повний текст джерелаAddepalli, Balasubrahmanyam, Suryadevara Rao, and Arthur G. Hunt. "Phage Display Library Screening for Identification of Interacting Protein Partners." In Methods in Molecular Biology, 147–58. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2175-1_13.
Повний текст джерелаOmar, Noorsharmimi, and Theam Soon Lim. "Construction of Naive and Immune Human Fab Phage-Display Library." In Methods in Molecular Biology, 25–44. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7447-4_2.
Повний текст джерелаChen, Peng-Hsun Chase, and Wenshe Ray Liu. "The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library." In Methods in Molecular Biology, 219–30. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1617-8_17.
Повний текст джерелаZhu, Kejia, Shanshan Wu, Hailing Ma, Ke Wu, Wenhui Ji, Shifei Yang, Xiaolan Fu, et al. "Screening of Ochratoxin a mimotopes in phage random 7-peptide library." In Advances in Civil Engineering and Environmental Engineering, Volume 2, 45–49. London: CRC Press, 2023. http://dx.doi.org/10.1201/9781003383031-8.
Повний текст джерелаSummer, Elizabeth J. "Preparation of a Phage DNA Fragment Library for Whole Genome Shotgun Sequencing." In Methods in Molecular Biology, 27–46. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-565-1_4.
Повний текст джерелаJakob, Valentin, Saskia Helmsing, Michael Hust, and Martin Empting. "Restriction-Free Construction of a Phage-Presented Very Short Macrocyclic Peptide Library." In Methods in Molecular Biology, 95–113. New York, NY: Springer US, 2019. http://dx.doi.org/10.1007/978-1-4939-9853-1_6.
Повний текст джерелаТези доповідей конференцій з теми "Phage library"
Spitzer, S. G., P. Usharani, A. D. Roser, C. K. Kasper, and S. G. Bajaj. "THE CATALYTIC TRIAD RESIDUES (HIS221, ASP269, SER365) AND THE BINDING POCKET RESIDUE (ASP359) IN FACTOR IXBm ELSINORE (IXBmLE) ARE NOT ALTERED." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644071.
Повний текст джерелаJones, Kelvin M., Rajeev Samant, Shree Singh, and Deepa Bedi. "Abstract 1078: Identification of peptides binding to mesenchymal subtype breast cancer from phage display peptide library." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1078.
Повний текст джерелаBezerra, Marcus, Andrea Maranhao, Igor Studart, Larissa Pontes, Marcela Fonseca, and Gilvan Furtado. "Construction of a scFv library using directed evolution for rituximab-based therapies: using phage display towards antibody affinity maturation." In IV International Symposium on Immunobiologicals & VII Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2019. http://dx.doi.org/10.35259/isi.sact.2019_32708.
Повний текст джерелаDing, Huihua, Fan-Lin Wu, Dan-Yun Lai, Yuan-Jia Tang, Zhao-Wei Xu, Ming-Liang Ma, Shu-Juan Guo, et al. "165 Identification of serum biomarkers for systemic lupus erythematosus using a library of phage displayed random peptides and deep sequencing." In 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5–8, 2019, Abstract Presentations. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-lsm.165.
Повний текст джерелаPloos van Amstel, J. K., A. L. van der Zanden, E. Bakker, P. H. Reitsma, and R. M. Bertina. "INDEPENDENT ISOLATION OF HUMAN PROTEIN S cDNA AND THE ASSIGNMENT OF THE GENE TO CHROMOSOME 3." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644638.
Повний текст джерелаAhmed, Kafil, Vyankatesh Pidiyar, Syed Ahmed, and Sanket Shah. "Development of anti-SARS-CoV-2 specific scFv antibody library from convalescent plasma of COVID-19 recovered patients using phage display technology." In International Symposium on Immunobiological. Instituto de Tecnologia em Imunobiológicos, 2021. http://dx.doi.org/10.35259/isi.2021_46568.
Повний текст джерелаPearson, Hannah. "Making Collection Management Manageable: A Three-Phase Approach to an Annual Subscription Review." In Charleston Library Conference. Purdue Univeristy, 2020. http://dx.doi.org/10.5703/1288284317143.
Повний текст джерелаOrcutt, Darby. "The User‐Driven Collection 4.0: The Next Phase in User‐Driven Monographic Acquisition." In Charleston Library Conference. Purdue University Press, 2016. http://dx.doi.org/10.5703/1288284316286.
Повний текст джерелаHuber, P., J. Dalmon, M. Laurent, G. Courtois, D. Thevenon та G. Marguerie. "CHARACTERIZATION OFTHE 5’FLANKING REGION FOR THE HUMAN FIBRINOGEN β GENE". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642889.
Повний текст джерелаRathemacher, Andrée, Robert Heaton, Noah Levin, and Christine Stohn. "Six Impossible Things: Moving KBART into the Next Decade." In Charleston Library Conference. Purdue Univeristy, 2020. http://dx.doi.org/10.5703/1288284317173.
Повний текст джерелаЗвіти організацій з теми "Phage library"
Pai, Jih T. Tumor Targeting with Phage Library. Fort Belvoir, VA: Defense Technical Information Center, July 2000. http://dx.doi.org/10.21236/ada383701.
Повний текст джерелаSiciliano, E. R., and E. D. Arthur. Medium-Energy Nuclear Data Library (MENDLIB): Phase 1. Office of Scientific and Technical Information (OSTI), October 1987. http://dx.doi.org/10.2172/5978252.
Повний текст джерелаCiezki, John G., and Robert W. Ashton. PEBB Feedback Control Low Library. Volume 1: Three-Phase Inverter Control Algorithms. Fort Belvoir, VA: Defense Technical Information Center, January 1999. http://dx.doi.org/10.21236/ada360711.
Повний текст джерелаBaughman, Sue, Ava Brillat, Gordon Daines, Greg Davis, Stephanie JH McReynolds, Margaret Roller, and Kevin Borden. Building a Community of Assessment: Final Report of the Research Library Impact Framework Pilot Initiative. Association of Research Libraries, March 2023. http://dx.doi.org/10.29242/report.rlif2023.
Повний текст джерелаEyal, Yoram, and Sheila McCormick. Molecular Mechanisms of Pollen-Pistil Interactions in Interspecific Crossing Barriers in the Tomato Family. United States Department of Agriculture, May 2000. http://dx.doi.org/10.32747/2000.7573076.bard.
Повний текст джерелаPinelli, Thomas E., John M. Kennedy, and Terry F. White. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 10. Summary Report to Phase 3 Academic Library Respondents Including Frequency Distributions. Fort Belvoir, VA: Defense Technical Information Center, August 1991. http://dx.doi.org/10.21236/ada252069.
Повний текст джерелаEpel, Bernard L., Roger N. Beachy, A. Katz, G. Kotlinzky, M. Erlanger, A. Yahalom, M. Erlanger, and J. Szecsi. Isolation and Characterization of Plasmodesmata Components by Association with Tobacco Mosaic Virus Movement Proteins Fused with the Green Fluorescent Protein from Aequorea victoria. United States Department of Agriculture, September 1999. http://dx.doi.org/10.32747/1999.7573996.bard.
Повний текст джерела