Готові списки джерел за темами / PanNEN

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Добірка наукової літератури з теми "PanNEN"

Автор: Grafiati
Опубліковано: 11 березня 2023

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Статті в журналах з теми "PanNEN"

1

Wen, Junmiao, Jiayan Chen, Di Liu, Xinyan Xu, Min Fan, and Zhen Zhang. "The Eighth Edition of the American Joint Committee on Cancer Distant Metastases Stage Classification for Metastatic Pancreatic Neuroendocrine Tumors Might Be Feasible for Metastatic Pancreatic Ductal Adenocarcinomas." Neuroendocrinology 110, no. 5 (July 30, 2019): 364–76. http://dx.doi.org/10.1159/000502382.

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Background: Significant modifications have been made to the 8th edition of the American Joint Committee on Cancer (AJCC) distant metastases (M) stage classification for metastatic pancreatic neuroendocrine tumors (PanNETs). We aimed to validate this revised classification among metastatic PanNET patients using the Surveillance, Epidemiology, and End Results database. We further sought to evaluate the feasibility of applying this classification to metastatic pancreatic neuroendocrine carcinoma (PanNEC) and pancreatic ductal adenocarcinoma (PDAC) patients. Methods: Stage IV pancreatic neuroendocrine neoplasm (PanNEN, including G1/G2 PanNET and G3 PanNEC classified according to the World Health Organization [WHO] 2010 grading scheme) and PDAC patients with metastatic disease diagnosed between 2010 and 2015 were identified and restaged according to the revised M stage classification for PanNET. Overall survival (OS) was compared using Kaplan-Meier analysis and log-rank test. Uni- and multivariate Cox regression models were utilized to identify prognostic factors. Results: A total of 1,371 stage IV PanNEN and 634 PDAC patients were included. Among PanNEN patients, liver (75.0%) was the most common metastatic site, followed by distant lymph nodes (8.5%), lung (8.4%), bone (7.3%), and brain (1.0%). The 5-year OS for PanNET patients with M1a, M1b, and M1c stage was 44.15, 53.32, and 19.70%, respectively. However, survival comparison showed no significant difference between M1a and M1b stages among PanNET patients. Similar findings were noted after applying this classification to PanNEC patients. Multivariate analysis showed that the age at diagnosis and the number of distant metastatic sites were independent prognostic factors for metastatic PanNEN patients. Interestingly, excellent survival discrimination by M stage among stage IV PDAC patients was noted (M1a vs. M1b vs. M1c, 5-year OS: 5.42, 2.46, and 0%, respectively). Conclusion: Our study is the first large sample-based validation of the AJCC 8th M stage classification for PanNET. The revised classification did not effectively stratify metastatic PanNEN patients. However, further study is warranted to validate this classification for PanNET patients according to the WHO 2017 classification. Interestingly, the revised M stage classification might be feasible for PDAC patients with metastatic disease.
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2

Azar, Ibrahim, Omid Yazdanpanah, Shiva Swaroop Bongu, Mohammed Najeeb Al Hallak, W. Michael Korn, Anthony Frank Shields, and Philip Agop Philip. "Molecular profiling of pancreatic neuroendocrine neoplasms (panNENs): A single-institution experience." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e16207-e16207. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16207.

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e16207 Background: PanNENs are rare with a heterogeneous pathophysiology and widely differing clinical course. Despite a recent update of the grading system, prognostication and prediction of response to therapy remain challenging. Somatostatin receptor aside, there are currently no predictive biomarkers or targeted agents for panNENs. Molecular profiling offers an opportunity to develop new drugs and personalize treatments. Methods: We compiled data from patients diagnosed with panNENs from Karmanos Cancer Institute between 2014 and 2020. Of the 35 patients with panNENs, 33 underwent Next Generation Sequencing (Caris Molecular Intelligence). Two tumor biopsies were insufficient for molecular analysis. Results: Of the 35 tumors analyzed, 11 were grade 1, 18 were G2, 2 were well-differentiated G3 and 4 were poorly differentiated pancreatic neuroendocrine carcinomas (panNEC). Median age at diagnosis was 61. 21 patients identified as White, 6 as Black and 8 as other. 21 were men. 28 patients were metastatic at diagnosis. The most frequently detected molecular alteration was MEN1 mutations (11 G1, 1 G1 and 1 G3). 3 G2 and 2 G3 tumors expressed PTEN mutations. All 3 p53 mutations were G3, 2 of them panNEC. An FGFR3 amplification was detected in a single G1 panNEN. Her2/Neu amplification was detected in a G2 tumor. Other frequent alterations were MGMT (4), TOP2A (4), ARID1A (3), TUBB3 (3) and TSC2 (3). 3 tumors were PD-L1 positive. All tumors were TMB non-high and MMR-proficient. Conclusions: Molecular profiling of panNEN can detect targetable alterations with currently validated commercial agents. panNENs are immunologically cold. Further genomic and epigenomic profiling studies can help understand the molecular underpinnings of pathophysiology and aid in the development of biology-driven targeted therapies.
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April-Monn, Simon Leonhard, Valentina Andreasi, Marco Schiavo Lena, Martin Carl Sadowski, Corina Kim-Fuchs, Michelle Claudine Buri, Avanee Ketkar, et al. "EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs)." Cancers 13, no. 19 (October 7, 2021): 5014. http://dx.doi.org/10.3390/cancers13195014.

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Pancreatic neuroendocrine neoplasms are epigenetically driven tumors, but therapies against underlying epigenetic drivers are currently not available in the clinical practice. We aimed to investigate EZH2 (Enhancer of Zest homolog) expression in PanNEN and the impact of EZH2 inhibition in three different PanNEN preclinical models. EZH2 expression in PanNEN patient samples (n = 172) was assessed by immunohistochemistry and correlated with clinico-pathological data. Viability of PanNEN cell lines treated with EZH2 inhibitor (GSK126) was determined in vitro. Lentiviral transduction of shRNA targeting EZH2 was performed in QGP1 cells, and cell proliferation was measured. Rip1TAG2 mice underwent GSK126 treatment for three weeks starting from week 10 of age. Primary cells isolated from PanNEN patients (n = 6) were cultivated in 3D as islet-like tumoroids and monitored for 10 consecutive days upon GSK126 treatment. Viability was measured continuously for the whole duration of the treatment. We found that high EZH2 expression correlated with higher tumor grade (p < 0.001), presence of distant metastases (p < 0.001), and shorter disease-free survival (p < 0.001) in PanNEN patients. Inhibition of EZH2 in vitro in PanNEN cell lines and in patient-derived islet-like tumoroids reduced cell viability and impaired cell proliferation, while inhibition of EZH2 in vivo in Rip1TAG2 mice reduced tumor burden. Our results show that EZH2 is highly expressed in high-grade PanNENs, and during disease progression it may contribute to aberrations in the epigenetic cellular landscape. Targeting EZH2 may represent a valuable epigenetic treatment option for patients with PanNEN.
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Nakano, Kenzo, Toshihiko Masui, Akitada Yogo, Yuichiro Uchida, Asahi Sato, Yosuke Kasai, Kazuyuki Nagai, Takayuki Anazawa, Yoshiya Kawaguchi, and Shinji Uemoto. "Chloroquine induces apoptosis in pancreatic neuroendocrine neoplasms via endoplasmic reticulum stress." Endocrine-Related Cancer 27, no. 7 (July 2020): 431–39. http://dx.doi.org/10.1530/erc-20-0028.

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Although pancreatic neuroendocrine neoplasms (PanNENs) are generally indolent, patients with distant metastasis have a dismal prognosis. Recently, the autophagy inhibitor chloroquine (CQ) has been shown to suppress the tumour growth of PanNENs, but the detailed mechanisms have not been elucidated. Furthermore, these results were obtained from poorly differentiated cell lines rather than well-differentiated cell lines, which is the most prevalent type in this tumour. To explore the mechanism and efficacy of CQ on PanNENs, we applied CQ to cell lines and evaluated the resulting apoptosis and endoplasmic reticulum (ER) stress. CQ treatment induced ER stress, and an unfolded protein response was activated through the PERK-eIF2α-ATF4 pathway, resulting in the expression of the pro-apoptotic protein C/EBP homologous protein (CHOP), which reflects ER-stress-mediated apoptotic cell death. Furthermore, hydroxychloroquine (HCQ) was effective in Men1 heterozygous-deficient (Men1+/ΔN3-8) mice, a mouse PanNEN model that is considered to correspond to human low-grade PanNEN. HCQ administration decreased tumour size in Men1+/ΔN3-8 mice. In the HCQ group, histological analyses revealed that proliferative activity was unchanged, but apoptosis was accelerated, accompanied by CHOP expression. These results suggest that autophagy inhibition by CQ/HCQ could be used for the treatment of PanNEN, including the well-differentiated type.
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5

van den Bold, Ingeborg. "Pannen en paprika’s." TBV – Tijdschrift voor Bedrijfs- en Verzekeringsgeneeskunde 22, no. 7 (September 2014): 319. http://dx.doi.org/10.1007/s12498-014-0138-y.

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6

Müringer, Alfred. "Pannen beim Versichererwechsel." Versicherungsmagazin 50, no. 10 (October 2003): 54–57. http://dx.doi.org/10.1007/bf03244419.

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7

Otto, Raik, Katharina M. Detjen, Pamela Riemer, Melanie Fattohi, Carsten Grötzinger, Guido Rindi, Bertram Wiedenmann, Christine Sers, and Ulf Leser. "Transcriptomic Deconvolution of Neuroendocrine Neoplasms Predicts Clinically Relevant Characteristics." Cancers 15, no. 3 (February 1, 2023): 936. http://dx.doi.org/10.3390/cancers15030936.

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Анотація:
Pancreatic neuroendocrine neoplasms (panNENs) are a rare yet diverse type of neoplasia whose precise clinical–pathological classification is frequently challenging. Since incorrect classifications can affect treatment decisions, additional tools which support the diagnosis, such as machine learning (ML) techniques, are critically needed but generally unavailable due to the scarcity of suitable ML training data for rare panNENs. Here, we demonstrate that a multi-step ML framework predicts clinically relevant panNEN characteristics while being exclusively trained on widely available data of a healthy origin. The approach classifies panNENs by deconvolving their transcriptomes into cell type proportions based on shared gene expression profiles with healthy pancreatic cell types. The deconvolution results were found to provide a prognostic value with respect to the prediction of the overall patient survival time, neoplastic grading, and carcinoma versus tumor subclassification. The performance with which a proliferation rate agnostic deconvolution ML model could predict the clinical characteristics was found to be comparable to that of a comparative baseline model trained on the proliferation rate-informed MKI67 levels. The approach is novel in that it complements established proliferation rate-oriented classification schemes whose results can be reproduced and further refined by differentiating between identically graded subgroups. By including non-endocrine cell types, the deconvolution approach furthermore provides an in silico quantification of panNEN dedifferentiation, optimizing it for challenging clinical classification tasks in more aggressive panNEN subtypes.
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8

Tsoli, Marina, Maria-Eleni Spei, Göran Wallin, Gregory Kaltsas, and Kosmas Daskalakis. "Association of a Palliative Surgical Approach to Stage IV Pancreatic Neuroendocrine Neoplasms with Survival: A Systematic Review and Meta-Analysis." Cancers 12, no. 8 (August 11, 2020): 2246. http://dx.doi.org/10.3390/cancers12082246.

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Анотація:
The role of primary tumor resection in patients with pancreatic neuroendocrine neoplasms (PanNENs) and unresectable distant metastases remains controversial. We aimed to evaluate the effect of palliative primary tumor resection (PPTR) on overall survival (OS) in this setting. We searched the MEDLINE, Embase, Cochrane Library, Web of Science and SCOPUS databases up to January 2020 and used the Newcastle–Ottawa scale (NOS) criteria to assess quality/risk of bias. A total of 5661 articles were screened. In 10 studies, 5551 unique patients with stage IV PanNEN and unresectable metastases were included. The five-year OS for PanNEN patients undergoing PPTR in stage IV was 56.6% vs. 23.9% in the non-surgically treated patients (random effects relative risk (RR): 1.70; 95% CI: 1.53–1.89). Adjusted analysis of pooled hazard ratios (HR) confirmed longer OS in PanNEN patients undergoing PPTR (random effects HR: 2.67; 95% CI: 2.24–3.18). Cumulative OS analysis confirmed an attenuated survival benefit over time. The complication rate of PPTR was as high as 27%. In conclusion, PPTR may exert a survival benefit in stage IV PanNEN. However, the included studies were subject to selection bias, and special consideration should be given to PPTR anchored to a multimodal treatment strategy. Further longitudinal studies are warranted, with long-term follow-up addressing the survival outcomes associated with surgery in stage IV disease.
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9

Gulde, Sebastian, Alessia Foscarini, Simon L. April-Monn, Edoardo Genio, Alessandro Marangelo, Swapna Satam, Daniel Helbling, et al. "Combined Targeting of Pathogenetic Mechanisms in Pancreatic Neuroendocrine Tumors Elicits Synergistic Antitumor Effects." Cancers 14, no. 22 (November 8, 2022): 5481. http://dx.doi.org/10.3390/cancers14225481.

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Анотація:
Pancreatic neuroendocrine neoplasms (PanNENs) are the second most common malignancy of the pancreas. Surgery remains the only curative treatment for localized disease. For patients with inoperable advanced or metastatic disease, few targeted therapies are available, but their efficacy is unpredictable and variable. Exploiting prior knowledge on pathogenetic processes involved in PanNEN tumorigenesis, we tested buparlisib (PI3K inhibitor) and ribociclib (CDK4/6 inhibitor), as single agents or in combination, in different preclinical models. First, we used cell lines representative of well-differentiated (INS-1E, NT-3) and poorly differentiated (BON-1) PanNENs. The combination of buparlisib with ribociclib reduced the proliferation of 2D and 3D spheroid cultures more potently than the individual drugs. Buparlisib, but not ribociclib, induced apoptosis. The anti-proliferative activity of the drugs correlated with downstream target inhibition at mRNA and protein levels. We then tested the drugs on primary islet microtissues from a genetic PanNET animal model (Men1-defective mice) and from wild-type mice: the drug combination was effective against the former without altering islet cell physiology. Finally, we treated PanNET patient-derived islet-like 3D tumoroids: the combination of buparlisib with ribociclib was effective in three out of four samples. Combined targeting of PI3K and CDK4/6 is a promising strategy for PanNENs spanning various molecular and histo-pathological features.
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10

IZUMO, WATARU, RYOTA HIGUCHI, TORU FURUKAWA, TAKEHISA YAZAWA, SHUICHIRO UEMURA, YUTARO MATSUNAGA, MASAHIRO SHIIHARA, et al. "Evaluation of the Significance of Lymphatic, Microvascular and Perineural Invasion in Patients With Pancreatic Neuroendocrine Neoplasms." Cancer Diagnosis & Prognosis 2, no. 2 (March 3, 2022): 150–59. http://dx.doi.org/10.21873/cdp.10089.

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Background: Some prognostic factors for pancreatic neuroendocrine neoplasms (PanNENs) have been reported; however, the significance of lymphatic, microvascular, and perineural invasion remains unclear. We aimed to clarify the role of these factors in PanNEN recurrence. Patients and Methods: We analyzed 138 patients who underwent curative pancreatectomy and were pathologically diagnosed with PanNEN. We evaluated the association between clinicopathological factors and the recurrence of PanNENs. Results: The numbers of patients with lymphatic, microvascular, and perineural invasion were 34 (25%), 43 (31%) and 17 (12%), respectively. Twenty-four patients (17%) had recurrences, and the 3, 5, and 10-year recurrence-free survival (RFS) rates were 88%, 84%, and 76%, respectively. The recurrence sites (with duplication) were mainly the liver (twenty-two patients), followed by the lymph nodes (seven patients), and bone (two patients). In multivariate analyses, grade 2-3 and the presence of microvascular invasion were significant risk factors for RFS (hazard ratio=7.5 and 7.9, respectively). When examining outcomes according to these factors, the 5-year RFS rates of patients with risk scores of 0, 1, and 2 were 100%, 91%, and 32%, respectively (p<0.001). Even in patients with grade 1 (n=97) or limited resection (enucleation, splenic-preserving distal pancreatectomy, central pancreatectomy, and duodenum-preserving pancreatic head resection, n=62), the presence of microvascular invasion was a significant risk factor for RFS (hazard ratio=13.4 and 18.0, respectively). Conclusion: The presence of microvascular invasion is an independent risk factor for recurrence in patients with PanNEN.
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Дисертації з теми "PanNEN"

1

Pannen, Hendrik [Verfasser]. "The ESCRT Machinery regulates Retromer dependent Transcytosis of Septate Junction Components in Drosophila / Hendrik Pannen." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2020. http://d-nb.info/1224099656/34.

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2

Pannen, Hans Derk [Verfasser], Karin [Akademischer Betreuer] Schnetz, and Jürgen [Akademischer Betreuer] Dohmen. "Analysis of transcriptional regulation by RcsB homo- and heterodimers in Escherichia coli / Hans Derk Pannen. Gutachter: Karin Schnetz ; Jürgen Dohmen." Köln : Universitäts- und Stadtbibliothek Köln, 2015. http://d-nb.info/1082030465/34.

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3

Krug, Sebastian [Verfasser], M. M. [Gutachter] Weber, and D. K. [Gutachter] Bartsch. "Identifikation und Charakterisierung von prognostischen und prädiktiven Markern in pankreatischen neuroendokrinen Neoplasien (PanNEN) / Sebastian Krug ; Gutachter: M. M. Weber, D. K. Bartsch." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2019. http://d-nb.info/121072975X/34.

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4

Bernardo, Papini Marcella Verfasser], Pannek [Akademischer Betreuer] Pannek, Pannek [Gutachter] Pannek, and Hans-Dietrich [Gutachter] [Haasis. "Robust Capacitated Vehicle Routing Problem with Uncertain Demands / Marcella Bernardo Papini ; Gutachter: Pannek Pannek, Hans-Dietrich Haasis ; Betreuer: Pannek Pannek." Bremen : Staats- und Universitätsbibliothek Bremen, 2019. http://d-nb.info/1196286310/34.

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5

Alert, Hans-Joachim. "Proteinabbau einheimischer Futtermittel im Pansen." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-119287.

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Mit Hilfe der Pansen-Beutel-Methode wurde an drei trockenstehenden Kühen der intraruminale Rohproteinabbau von Futtermitteln ermittelt. Daraus wurden folgende UDP-Gehalte (k = 5 %/h) abgeleitet: Sojaextraktionsschrot: 30 %, Rapsextraktionsschrot: 33 %, Rapskuchen: 15 %, Roggenpressschlempe: 43 %, Weizen/Gerste-Trockenschlempe: 25 %, Ackerbohnen: 22-26 %, Körnerfuttererbsen: 20-24 %, Blaue Lupinen: 27-35 %, Leguminosen-Gras-Gemenge: 18-35 %. Bei Körnermaisschrot (trocken bzw. feucht konserviert) wurde der intraruminale Stärkeabbau bestimmt: trocken 42 % Abbau, feucht 18 % Abbau. Außerdem wurde an vier hochleistenden Kühen die Wirkung von Einzelfuttermitteln im Rahmen von Mischrationen auf die Pansenfermentation untersucht (pH-Wert, NH 3 -Gehalt, Gehalt an FFS im Pansensaft). Trotz des höheren intraruminalen Stärkeabbaus führte Feuchtkornmais zu keinem erhöhten Acidoserisiko (etwa gleicher Pansen-pH-Wert-Verlauf wie bei Trockenmais). Anhand der NH 3 -Gehalte im Pansensaft wurde ein verringerter Rohproteinabbau bei Einsatz des pansengeschützten Sojaextraxtionsschrots Soypass 50 nachgewiesen. Durch mikronisierte Rapssaat in der TMR konnte der Rohfettgehalt in der Rationstrockenmasse auf > 6 % erhöht werden, ohne dass die Pansenfermentation nachteilig beeinflusst wurde. Die Broschüre fasst alle Untersuchungsergebnisse zusammen.
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6

Raoult, Olivier. "Diagnostic de pannes des systèmes complexes." Phd thesis, Grenoble INPG, 1989. http://tel.archives-ouvertes.fr/tel-00332209.

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Trois entités caractéristiques du problème de diagnostic sont dégagées: le langage d'observation, la référence de bon fonctionnement et le langage de qualification. Le langage d'observation déterminé l'information perceptible; la référence de bon fonctionnement introduit le concept de panne et le langage de qualification définit l'ensemble des réponses possibles du système
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7

Arsan, Murad Ismet. "Observateurs et diagnostic automatique de pannes." Toulouse, ENSAE, 1994. http://www.theses.fr/1994ESAE0019.

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Le travail présenté dans cette thèse s'inscrit dans le contexte général du diagnostic des systèmes dynamiques à partir de modèles en utilisant la théorie des observateurs. Dans un premier temps, nous présentons les observateurs élémentaires de dimension un, qui ne sont pas forcément les observateurs d'état mais d'une combinaison linéaire d'état. Nous examinons aussi les propriétés fondamentales et la création de banques de ces observateurs particuliers. Deuxièmement, nous introduisons différentes procédures de génération des résidus découplés en utilisant les observateurs élémentaires. Nous détaillons les conditions d'existence des résidus générés et etudions leur sensibilisation afin d'obtenir des résidus structurés. Par la suite, nous nous intéressons au problème de la robustesse de rédidus par rapport aux incertitudes dans la modélisation du système. Une première méthode proposée compare deux obseravtions, l'une biaisée et l'autre rendue non biaisée par les variations paramétriques ; l'estimation des paramètres inconnus est déduite de cette comparaison. En revanche, si les directions de paramètres incertains sont trop nombreuses, il devient très difficile de générer l'observateur non biaisé. Dans ce cas, nous proposons une deuxième méthode qui comprend l'identification non linéaire des paramètres incertains et qui utilisent les résidus structurés pour détecter et localiser l'anomalie. Les deux méthodes présentées envisagent des calculs à effectuer en temps réel. Dernièrement, nous montrons l'équivalence (théorique, fonctionnelle et de mise en oeuvre) entre deux techniques de génération de résidus : celle fondée sur l'espace de parité et celle fondée sur les observateurs. L'originalité de notre approche réside dans l'aspect constructif de notre développement.
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Raoult, Olivier Lux Augustin Mossière Jacques Demogeot Jacques. "Diagnostic de pannes des systèmes complexes." S.l. : Université Grenoble 1, 2008. http://tel.archives-ouvertes.fr/tel-00332209.

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9

Khier, Mohammed. "Estimation du taux de panne." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37606568t.

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10

Huc, Florian. "Conception de Réseaux Dynamiques Tolérants aux Pannes." Phd thesis, Université de Nice Sophia-Antipolis, 2008. http://tel.archives-ouvertes.fr/tel-00472781.

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Cette thèse aborde différents aspects de la conception d'un réseau de télécommunications. Un tel réseau utilise des technologies hétérogènes : liens antennes-satellites, radio, fibres optiques ou bien encore réseaux embarqués dans un satellite. Les problématiques varient en fonction de la partie du réseau considérée, du type de requêtes et de l'objectif. Le cas des requêtes de type paquets est abordé dans le cadre des réseaux en forme de grille, mais le thème principal est le routage de requêtes de type connections (unicast et multicast). Les objectifs considérés sont : la conception d'un réseau embarqué dans un satellite de télécommunication, de taille minimum et tolérant des pannes de composants; le dimensionnement des liens d'un réseau afin qu'il supporte des pannes corrélées ou qu'il offre une bonne qualité de service, ou s'il autorise des connections {\em multicast}; le dimensionnement de la taille des buffers d'un réseau d'accés radio; et l'optimisation de l'utilisation des ressources d'un réseau dynamique orienté connections. Dans tous ces cas la problématique du routage de connections est centrale. Mon approche consiste à utiliser la complémentarité de techniques algorithmique et d'optimisation combinatoire ainsi que d'outils issus de la théorie des graphes tels la pathwidth et des notions reliées -process number, jeux de captures et treewidth-, différents types de coloration -impropre et pondérée, proportionnelle, directed star colouring-, les graphes d'expansion et des techniques de partitions telle la quasi partition.
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Книги з теми "PanNEN"

1

Foelkel, Frithjof. Onder de pannen: Roman. Amsterdam: Meulenhoff, 1995.

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2

Kahl, Ernst. Prost Mahlzeit!: Kulinarische Pannen und andere Delikatessen. Zürich: Kein & Aber, 2010.

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3

Dirk, De Prins, ed. Duet met potten en pannen: Koken met Johan Segers en Dirk De Prins. Antwerpen: BMP Culinair, 2006.

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4

Zittlau, Jörg. Warum Robben kein Blau sehen und Elche ins Altersheim gehen: Pleiten und Pannen im Bauplan der Natur. Berlin: Ullstein, 2008.

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5

Sarang pannŭn anae, chonʼgyŏng pannŭn nampʻyŏn. Sŏul Tʻŭkpyŏlsi: Ŭlchi Sŏjŏk, 1989.

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6

Czakó, Gábor. Pannon krétakör. Budapest: Válasz Könyvkiadó, 2001.

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7

Cookson, Catherine. Rok panien. Bratislava: Slovensky spisovatel, 1996.

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8

Miklós, Mészöly. Pannon töredék. [Budapest]: Trikolor, 2001.

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9

1949-, Halmos Ferenc, Aradi Nóra, Fehér Katalin, and Járai-Komlódi Magda, eds. Pannon enciklópedia. Budapest: Pannon, 1993.

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10

Gulazāra. Pichale panne. Nayī Dillī: Bhāratīya Jñānapīṭha, 2012.

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Більше джерел

Частини книг з теми "PanNEN"

1

Schmitt-Thomas, Karlheinz G. "Ereignisketten von Pannen zu Katastrophen." In Integrierte Schadenanalyse, 21–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-46134-1_4.

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2

Schmitt-Thomas, Karlheinz G. "Ereignisketten von Pannen zu Katastrophen." In Integrierte Schadenanalyse, 20–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-07947-8_5.

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3

La Rosa, Stefano, and Amedeo Sciarra. "Neuroendocrine Neoplasm of the Pancreas (PanNEN)." In Pathology of the Pancreas, 152–54. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-62416-3_5543.

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4

La Rosa, Stefano, and Amedeo Sciarra. "Neuroendocrine Neoplasm of the Pancreas (PanNEN)." In Encyclopedia of Pathology, 1–3. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-28845-1_5543-1.

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5

Schneider, Alexander. "Die häufigsten Pannen im Zusammenhang mit Arbeitsverhältnissen." In Recht in der Unternehmenspraxis, 59–85. Wiesbaden: Gabler Verlag, 2004. http://dx.doi.org/10.1007/978-3-322-96338-3_4.

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6

Schmitt, Irmtraud. "Pleiten, Pech und Pannen: Was tun Sie, wenn…" In Praxishandbuch Event Management, 139–42. Wiesbaden: Gabler Verlag, 2012. http://dx.doi.org/10.1007/978-3-8349-7098-5_7.

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7

Kalus, Kunigunde. "Das große 1x1 des heutigen Wirtschaftens – auch Pannen kommen schon mal vor." In Wie wirtschaftet die Welt?, 123–81. Wiesbaden: Springer Fachmedien Wiesbaden, 2017. http://dx.doi.org/10.1007/978-3-658-16829-2_4.

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8

Schnyder, Peter. "Die Panne." In Dürrenmatt-Handbuch, 73–75. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05314-5_17.

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9

Irving, E. "The Case for Pangea B, and the Intra-Pangean Megashear." In Timescales Of The Paleomagnetic Field, 13–27. Washington, D. C.: American Geophysical Union, 2013. http://dx.doi.org/10.1029/145gm02.

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10

Schäfer, Michael. "ÖPP auf staatlicher Ebene: Warum die Bilanz vorwiegend Pleiten, Pech und Pannen aufweist und wir trotzdem nicht schwarz-weiß malen dürfen." In Öffentlich-Private Partnerschaften, 199–211. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-28273-8_7.

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Тези доповідей конференцій з теми "PanNEN"

1

Wicaksono, Ardi Ciptadi, Hari Prasetyo, and Titien Suhermiatin. "Pengaruh Paclobutrazol dan Dosis Pupuk Phospor untuk Meningkatkan Produksi Benih Katang Tanah (Arachis hypogeae L.) Varietas Takar Dua." In Seminar, Expo dan Diskusi (SEEDs) Perbenihan Nasional 2017. Jember: AGROPROSS, National Conference Proceedings of Agriculture, 2017. http://dx.doi.org/10.25047/agropross.2017.21.

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Анотація:
Ketersediaan tanaman pangan terutama kacang tanah diupayakan dapat memenuhi kebutuhan masyarakat yang terus meningkat. Penelitian ini dilakukan dengan harapan dapat meningkatkan hasil panen serta kualitas benih kacang tanah dengan pengaplikasi paclobutrazol dan penggunaan dosis SP36 yang efektif. Rancangan Acak Kelompok (RAK) (2 faktor dan 3 ulangan). Faktor pertama yaitu paclobutrazol (4 taraf) dan faktor kedua adalah dosis pupuk SP36 (3 taraf). Hasil menunjukan bahwa perlakuan dengan penerapan paclobutrazol berpengaruh terhadap peningkatan hasil panen dan kualitas benih kacang tanah. Pada perlakuan aplikasi paclobutrazol terbaik untuk meningkatkan hasil panen yaitu tanpa menggunakan paclobutrazol dan pada penggunaan dosis SP36 125 kg/ha merupakan hasil yang paling tinggi yaitu 1.05 ton/ha benih bernas. Penggunaan dosis SP36 terbaik untuk meningkatkan kualitas benih yaitu 125 kg/ha dengan nilai 98.78% untuk daya perkecambahan dan 98,78% unutk jumlah kecepatan perkecambahan benih. Interaksi antara konsentrasi paclobutrazol dan dosis SP36 tedapat pada parameter tinggi tanaman dan jumlah bunga.
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2

Triaire, Sylvie. "Le livre des pannes. Bouvard et Pécuchet." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5816.

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3

Rabau, Sophie. "Comment saboter un texte ?" In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5779.

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4

Laurichesse, Jean-Yves. "Les Âmes fortes de Giono ou le récit comme contra-diction." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5792.

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5

Massonaud, Dominique. "Aragon romancier : Balbutiements et coups d’arrêts." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5800.

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6

Naïm, Jérémy. "Robbe-Grillet, rouleur de mécaniques." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5786.

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7

Courrént, Mireille. "En panne sur l’autoroute. Le roman grec ou comment draguer son lecteur avec un véhicule neuf et le plein d’essence sur une voie de grande circulation." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5798.

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8

Abecassis, Jack I. "La Voie Lactée et Le Fantôme de la Liberté de Luis Buñuel, une Étude des Contraintes Cognitives de la Narration." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5802.

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9

Blanc, Anne-Lise. "Christian Gailly, l’art de parer la panne." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5790.

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10

Blaise, Marie. "Melville, l’homme-confiance et le faiseur de nœuds." In "Le coup de la panne". Ratés et dysfonctionnements textuels. Fabula, 2018. http://dx.doi.org/10.58282/colloques.5814.

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Звіти організацій з теми "PanNEN"

1

Bertolini, Louis, Nathan Brannon, Jared Olson, Bernard Price, Robert Wardle, Mike Steinzig, and Michael Winfield. Pantex Falling Man - Independent Review Panel Report. Office of Scientific and Technical Information (OSTI), November 2014. http://dx.doi.org/10.2172/1164980.

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2

Moretz, Colleen. Transparent Pannier. Ames: Iowa State University, Digital Repository, 2017. http://dx.doi.org/10.31274/itaa_proceedings-180814-228.

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3

Mosquera Castro, Tania, Roberto Bartolomé Abraira, Mario César Vila, Esperanza Martín Hernández, and Francisco Alonso Toucido. Alfar de Panxón. Institut Català d’Arqueologia Clàssica, 2022. http://dx.doi.org/10.51417/figlinae_071.

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Анотація:
Ficha del yacimiento Alfar de Panxón ubicado a Nigrán (Pontevedra) incluida en el proyecto "Figlinae Hispanae (FIGHISP). Catálogo en red de las alfarerías hispanorromanas y estudio de la comercialización de sus productos".
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4

Miller, Jacob K. Pantex Forklift Field Measurement Report. Office of Scientific and Technical Information (OSTI), March 2019. http://dx.doi.org/10.2172/1544967.

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5

Chen, K. C., and K. O. Merewether. Pantex lightning study recommendations report. Office of Scientific and Technical Information (OSTI), December 1993. http://dx.doi.org/10.2172/10115273.

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6

Snyder, S. F. Pantex Plant meteorological monitoring program. Office of Scientific and Technical Information (OSTI), July 1993. http://dx.doi.org/10.2172/10176440.

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7

Ruslan, Kadir. Produktivitas Tanaman Pangan dan Hortikultura. Jakarta, Indonesia: Center for Indonesian Policy Studies, 2021. http://dx.doi.org/10.35497/345661.

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8

Cheriton, David R., Dale B. Henderson, Duncan C. Miller, David L. Mills, and Stuart D. Cheshire. Scaleability Panel Review. Fort Belvoir, VA: Defense Technical Information Center, October 1993. http://dx.doi.org/10.21236/ada285508.

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9

Herring, Angela. LSSw Panel Introduction. Office of Scientific and Technical Information (OSTI), April 2022. http://dx.doi.org/10.2172/1864970.

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10

Dadfarnia, Mehdi. Panel Summary Report:. Gaithersburg, MD: National Institute of Standards and Technology, 2022. http://dx.doi.org/10.6028/nist.ir.8445.

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