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Добірка наукової літератури з теми "Osteoarthritis Risk factors"

Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 29 січня 2023

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Статті в журналах з теми "Osteoarthritis Risk factors"

Felson, David T. "Risk Factors for Osteoarthritis." Clinical Orthopaedics and Related Research 427 (October 2004): S16—S21. http://dx.doi.org/10.1097/01.blo.0000144971.12731.a2.

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Cimmino, Marco A., and Massimiliano Parodi. "Risk Factors for Osteoarthritis." Seminars in Arthritis and Rheumatism 34, no. 6 (October 2004): 29–34. http://dx.doi.org/10.1016/j.semarthrit.2004.03.009.

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Smetanin, S., and A. Lychagin. "RISK FACTORS FOR KNEE OSTEOARTHRITIS." Врач 31, no. 7 (2020): 81–84. http://dx.doi.org/10.29296/25877305-2020-07-16.

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Yan, Yi Lin Hong. "The Risk factors of Osteoarthritis." Highlights in Science, Engineering and Technology 14 (September 29, 2022): 90–99. http://dx.doi.org/10.54097/hset.v14i.1597.

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Osteoarthritis (OA) is the one type of arthritis which affects 7% of the population and is the 15th leading cause of disability. However, the etiology of this disease is complex and its pathogenesis is still under investigation. The pathological changes seen in OA most commonly include synovitis, osteophyte formation, cartilage degradation, thickening of the subchondral bone, etc. which may lead to symptoms such as stiffness, movement disorder and swelling. OA generally starts with the damage of the articular cartilage of the synovial joint which later leads to a cascade of effects that ultimately leads to joint destruction. Some of the identified risk factors of OA include old age, gender, genetics, obesity, and neurological disorder. However, even with these factors being identified, many of the mechanisms responsible for progression to OA behind these risk factors remain unclear. This paper reviews different articles regarding the risk factors of OA and summarizes the possible mechanisms behind each risk factor.

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Berryman, Phyllis, Eileen Lukes, Marilyn A. Aluoch, and Hesborn O. Wao. "Risk Factors for Occupational Osteoarthritis." AAOHN Journal 57, no. 7 (July 1, 2009): 283–90. http://dx.doi.org/10.3928/08910162-20090625-10.

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Zvekic-Svorcan, Jelena, Bojana Stamenkovic, Ivana Minakovic, Rastislava Krasnik, Tanja Jankovic, and Aleksandra Mikov. "Risk factors for hand osteoarthritis." Medical review 73, no. 3-4 (2020): 81–87. http://dx.doi.org/10.2298/mpns2004081z.

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Introduction. Hand osteoarthritis is a joint degenerative disease characterized by hand deformities affecting the hand strength and function, leading to greater disability and increased healthcare utilization. The objective of this study was to estimate the impact of different risk factors on the incidence of hand osteoarthritis. Material and Methods. The study was a prospective cross-sectional study conducted at the Special Hospital for Rheumatic Diseases Novi Sad, Serbia, during a one year period (2017 - 2018). It included 100 postmenopausal women aged 60 to 70 years presenting with pain in the hands ? 3 according to the visual analogue scale. All respondents were divided into two groups, according to radiographic findings graded using the Kellgren-Lawrence scale. Risk factors responsible for the development of hand osteoarthritis were examined and the research procedure included medical history data, physical examination of the hand joints, anthropometric measurements, and laboratory tests. Statistical processing and analysis was performed using Statistical Package for the Social Sciences ver. 25. Results. Statistically significant differences were found between the two groups in relation to positive family history of degenerative changes in the hand joints (p = 0.000), as well as in relation to metabolic syndrome (p = 0.001). Conclusion. A positive family history of degenerative changes of the hands and presence of metabolic syndrome are significant risk factors for the development of hand osteoarthritis.

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Kolber, Morey J., William J. Hanney, Scott W. Cheatham, and Paul A. Salamh. "Risk Factors for Hip Osteoarthritis." Strength and Conditioning Journal 39, no. 3 (June 2017): 35–41. http://dx.doi.org/10.1519/ssc.0000000000000222.

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Aluoch, Marilyn A., Hesborn O. Wao, Phyllis Berryman, and Eileen Lukes. "Risk Factors for Occupational Osteoarthritis." AAOHN Journal 57, no. 7 (July 2009): 283–92. http://dx.doi.org/10.1177/216507990905700706.

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MCALINDON, T., and D. T. FELSON. "Nutrition: risk factors for osteoarthritis." Annals of the Rheumatic Diseases 56, no. 7 (July 1, 1997): 397–400. http://dx.doi.org/10.1136/ard.56.7.397.

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Sowers, MaryFran. "Epidemiology of risk factors for osteoarthritis: systemic factors." Current Opinion in Rheumatology 13, no. 5 (September 2001): 447–51. http://dx.doi.org/10.1097/00002281-200109000-00018.

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Більше джерел

Дисертації з теми "Osteoarthritis Risk factors"

Abdul-Rahim, Hunar Attoof. "Morphological risk factors in hip osteoarthritis." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606376.

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Purpose: Variation in morphology in the proximal femur and pelvis (e.g. acetabular dysplasia, non-spherical femoral head) can biomechanically compromise the hip joint and predispose to hip osteoarthritis (OA). Such morphological variation may in part explain the heritability of hip OA. The objective of this study was to evaluate a range of 2-dimensional morphological measures on standard radiographs to determine: normal range, right: left symmetry, age and gender differences; and to investigate whether they are associated with the risk of hip OA. Methods: A nested case control study was undertaken in 566 unilateral hip OA cases and 1108 controls in the established Nottingham Genetics of Osteoarthritis and Lifestyle (GOAL) database. Unaffected hips of unilateral hip OA cases were compared to the normal controls, under the assumption that similar morphological features would be observed for the affected hips prior to the development of hip OA. Definition of radiographic hip OA was joint space width (JSW) ~ 2.5 mm. Standardized antero-posterior (AP) radiographs of the pelvis were used to measure the morphological features. Measurements were performed by a single observer and the reproducibility was evaluated at baseline, mid and end of the study. Normal values, thresholds (mean±1.96SD) and symmetry of the features were derived from the control subjects. The intra-observer reliability was examined using intra-class correlation coefficient (ICC). Odds ratio (OR) and 95% confidence interval (Cl) were calculated for association. Logistic regression was used to adjust for age, gender and body mass index (BM!). Measurements were divided into tertiles to examine dose response. ii Results: The intra-observer reliability

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Bottomley, Nicholas J. "Anteromedial osteoarthritis : a surgical perspective of incidence, progression and risk factors." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:34c87265-bbae-4018-b120-ef1d6bed73aa.

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Anteromedial osteoarthritis of the knee (AMOA) has been defined anatomically, histologically and radiologically and yet little is known about the epidemiology of the disease or the risk factors involved in the development of the disease. The broad aim of this thesis was to combine clinical insight with the utilisation of modern, large epidemiological datasets to provide information to inform better the clinical management of patients with AMOA. Specifically, the prevalence and incidence of AMOA, the time taken to progress from early disease to severe disease that may require surgical intervention, the radiological characterisation of disease and the assessment of mechanical risk factors implicit in the development of this pattern of disease are investigated. A cross-sectional study of the radiological prevalence of AMOA in a symptomatic cohort in a specialist secondary care knee clinic showed that AMOA was the commonest pattern of knee OA, present in more than 60% of symptomatic subjects. Less than 25% of subjects with AMOA presented with advanced or 'bone-on-bone' disease, emphasising the clinical importance of understanding the progression from earlier stages of disease to this advanced stage. A 20-year longitudinal radiographic study was performed on 1000 women to describe the prevalence, incidence and progression of AMOA. The prevalence of AMOA was 43% and the incidence over 20-years was 0.4. Life table analysis showed that the risk of developing advanced AMOA in a previously normal knee was 2.6%. Of those subjects with early radiological AMOA, 11% progressed to advanced 'bone-on-bone' disease within 10 years and 37% within 20 years. The role of mechanical risk factors in the development of AMOA showed that both anatomical limb and proximal tibial alignment were significantly more varus aligned in those that developed AMOA at 20-years. Assessment of the shape of the medial tibial plateau in a longitudinal MRI study showed that the angle of the upslope at the anterior aspect of the plateau was significantly increased in the group that subsequently developed AMOA. To enable AMOA to be studies in future MRI studies, the MRI description of the disease was defined. In summary, AMOA was shown to be the most common pattern of knee OA both in symptomatic surgical cohorts and in the community. The progression of the disease from an early stage to an advanced stage, which may require surgical intervention, was described for the first time. To enable better the recognition of AMOA in modern epidemiological studies, the MRI description of AMOA was defined and the clinical relevance of modern MRI was discussed. The anatomical alignment of the limb, the alignment of the proximal tibia and the morphology of the tibial plateau were all shown to have a role in the development of AMOA. Addressing these mechanical factors may provide a therapeutic surgical target for the management of patients with AMOA.

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Norvell, Daniel C. "Knee pain and symptomatic osteoarthritis after traumatic unilateral lower extremity amputation : prevalence and risk factors /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/10863.

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Cooper, Dale. "The risk factors associated with the prevalence of pain and self-reported physician-diagnosed osteoarthritis in Great Britain's Olympians." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/37890/.

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Background: Affecting approximately one in four adults over the age of 50 years in the UK, knee pain is a leading cause of disability in the elderly and bears a significant economic cost. Despite the plethora of studies that have investigated the factors associated with the onset of knee pain and osteoarthritis (OA) in the sedentary population, relatively little is known about the prevalence and factors associated with musculoskeletal pain and OA in an athletic sporting population. Objectives: This study aimed to: (1) describe the injury patterns, the prevalence of pain, and OA in Great Britain’s (GB) Olympians; (2) determine in GB Olympians aged 40 years and older the risk of pain and OA at three joints - the hip, knee and the lumbar spine; and (3) identify the individual risk factors associated with joint pain and OA in GB Olympians aged 40 years and older. Methods: This was a cross-sectional study design with an internal nested-case control study. A web-based and / or paper questionnaire was distributed by email and / or post to 2742 GB Olympians living in 30 different countries. The questionnaire was used to collect data on risk factors associated with the onset of pain and OA. The presence of OA was defined by a self-reported physician-diagnosis. Pain was self-reported using a body manikin, and defined as pain in or around the selected joint on most days for at least one month. The most severe limb was selected as the index joint for data analysis, if bilateral. Three separate models of binary logistic regression were constructed to examine the covariates that were associated with pain at the hip, knee, and the lumbar spine. A further three models were constructed to examine the covariates associated with OA at the aforementioned joints. Covariates were identified for analysis, and those that were associated with pain or OA (P < 0.25) were purposefully fitted into a multivariable regression model. The final regression models were constructed by refitting, one at a time, the covariates that had previously been excluded until all of the covariates and interactions that were clinically relevant or significant at traditional levels (P < 0.05) were included. Relative risk (RR) was estimated using odds ratio (OR), and confounding factors were adjusted (aOR) using logistic regression. The Faculty of Medicine and Health Sciences Research Ethics Committee at the University of Nottingham approved the study. Results: The response rate was 26%, with 714 returns achieved between the 22nd of May 2014 and the 31st of January 2015. The questionnaires were returned from GB Olympians living in 15 different countries, including the UK. The age of the GB Olympians recruited ranged from 19 to 97 years, with a mean age of 58.76 + 16.79 years. Fifty-seven per cent of those recruited were male (n = 405) and 43% were female (n = 309). The age of male GB Olympians recruited ranged from 22 to 97 years, with a mean age of 63.00 + 16.30 years. The age range of female GB Olympians recruited ranged from 19 to 93 years, with a mean age of 53.20 + 15.78 years. A total of 821 significant injuries were reported, resulting in an injury rate of 1150 significant injuries per 1000 registered GB Olympians, with 62% reporting they had sustained at least one significant injury (n = 441). Cartilage injuries, joint sprain (injury of joint and / or ligaments), and ligament ruptures were prominent in those with knee pain and knee OA. Intervertebral disc injuries, contusions and joint related injury were common in those with pain and OA at the lumbar spine. Pain was most prevalent at the lumbar spine (32.7%), knee (25.6%), hip (23.0%), and the ankle (14.1%). Osteoarthritis was most prevalent at the knee (14.2%), hip (11.1%), lumbar spine (5.0%), and the ankle (1.3%). Female gender and older age were significantly associated with lumbar spine OA, and older age and a previous significant hip injury were significantly associated with the prevalence of hip OA. Ageing and body mass index (BMI) (kg/m2), a previous significant knee injury and early-life (20-29 years) generalised joint hypermobility (GJH) (Beighton > 4/9) were found to be significantly associated with the prevalence of knee OA. The strongest factors associated with knee pain were a prior significant knee injury, early-life (20-29 years) varus knee alignment, competing in weight-bearing loading sports, widespread pain, and a higher body mass index (kg/m2). Factors associated with hip pain included a previous significant hip injury and competing in weight-bearing loading sports. A one-unit increase in age and BMI (kg/m2), and a prior significant lumbar spine injury were significantly associated with lumbar spine pain. A one-unit increase in physical well-being was significantly associated with a lower prevalence of pain at the hip and knee. Conclusion: This study found that: 1) injury appeared to be constantly the strongest risk factor for pain at the knee, hip and the lumbar spine, as well as OA at the hip and knee; 2) in GB Olympians aged 40 years and older, the knee was most likely affected by OA, and the lumbar spine by pain; 3) participation in weight-bearing loading sports was associated with hip and knee pain, but not hip and knee OA; and 3) generalised joint hypermobility (Beighton > 4/9) appeared to be not a risk factor for injury, and nor was it a risk factor for all joint pain/OA, except OA at the knee joint. Female GB Olympians with early-life GJH were more vulnerable to knee OA than their male counterparts. Future research is needed to help determine whether or not GJH is a risk factor associated with the onset of knee OA in the general population, particularly among females. As one of the few modifiable risk factors, joint injury prevention should be part of the future initiatives to reduce the risk of OA, along with maintaining a healthy body weight.

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Limer, Kate Louise. "Assessing the risk of environmental factors and candidate susceptibility genes and their interactions on large joint osteoarthritis in a case : control study." Thesis, Nottingham Trent University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444623.

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Barros, Hilton José Melo. "Medidas radiográficas relacionadas ao risco de ocorrência de osteoartrite do quadril." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-05032010-125943/.

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O estudo busca determinar fatores predisponentes para osteoartrite do quadril, por meio da avaliação de parâmetros radiográficos nos quadris de indivíduos idosos. Foram realizadas medições em radiografias de 106 indivíduos com idade acima de 60 anos, sendo um grupo com osteoartrite do quadril e um segundo grupo de indivíduos sem osteoartrite (grupo controle). As incidências radiográficas utilizadas foram ântero-posterior da pelve em ortostase, falso perfil de Lequesne e Dunn a 45 graus de flexão do quadril. Após aplicação de critérios de seleção bem definidos para osteoartrite primária do quadril, o número de quadris avaliados foi 112 quadris de indivíduos normais e 72 quadris de indivíduos com osteoartrite. Os parâmetros radiográficos estudados foram ângulo centro-borda de Wiberg, ângulo de Tönnis, índice acetabular de profundidade por diâmetro, percentual de cobertura da cabeça do fêmur, ângulo colo-diafisário, ângulo centro-borda anterior, offset entre a cabeça e o colo do fêmur, ângulo alfa, esfericidade da cabeça do fêmur e versão do acetábulo. As medidas radiográficas ângulo colo-diafisário, ângulo alfa, índice acetabular de profundidade por diâmetro e percentual de cobertura da cabeça do fêmur apresentaram valores médios significativamente diferentes nos pacientes com osteoartrite primária, quando comparados aos do grupo controle, sugerindo serem fatores predisponentes para a osteoartrite do quadril
This study aimed to determine factors that predispose towards hip osteoarthritis, by means of evaluating the radiographic parameters of elderly individuals hips. Radiographic measurements were made on 106 individuals aged 60 years or over: one group with hip osteoarthritis and another group of individuals without osteoarthritis (control group). The radiographic views used were the antero-posterior view of the pelvis in orthostatic position, Lequesnes false profile and Dunns view with 45 degrees of hip flexion. After applying well-defined selection criteria for primary osteoarthritis of the hip, the numbers of hips evaluated were 112 hips from normal individuals and 72 hips from individuals with osteoarthritis. The radiographic parameters studied were the Wiberg center-edge angle, Tönnis angle, acetabular index of depth to diameter, percentage coverage of the femoral head, neck-shaft angle, anterior center-edge angle, femoral neck-head offset, alpha angle, sphericity of the femoral head and acetabular version. The radiographic measurements of the neck-shaft angle, alpha angle, acetabular index of depth to diameter and percentage coverage of the femoral head presented mean values that were significantly different between the patients with idiopathic osteoarthritis and the control group. This suggests that these factors may predispose towards hip osteoarthritis

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Jelena, Zvekić-Svorcan. "Povezanost funkcijskog stanja šake u osteoartrozi i koštane mase merene centralnom dvostrukom apsorpciometrijom X-zraka kosti kod žena u postmenopauzi." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=109650&source=NDLTD&language=en.

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UVOD: Artroza šaka predstavlja jednu od najčešćih mišićno-skeletnih bolesti. Manifestuje se bolom, nekada otokom, deformacijom i gubitkom funkcije šaka. Postoje različita mišljenja o povezanosti osteoartroze (OA) i osteoporoze (OP) kao dva najčeša skeletna poremećaja. CILJ: istraživanja je da se utvrde faktori rizika za nastanak OA šaka, uporedi mineralna koštana gustina kod pacijenata sa OA šaka sa kontrolnom grupom i utvrdi značaj metaboličkog sindroma kod pacijenata sa OA šaka. MATERIJAL I METODE: Istraživanje je obavljeno u periodu od jedne godine kod bolesnika sa OA šaka – eksperimentalna grupa, i u kontrolnoj grupi bez OA. OA šaka je definisana na osnovu bola, klinički prisutnih deformiteta šaka kod žena u postmenopauzi starosne dobi od 60-70 godina i radiografskih promena ( drugog do četvrtog stepena prema Kellgren-Lowrencovoj skali). Analizirani su faktori rizika odgovorni za nastanak OA šaka, povezanost OA šaka sa snagom stiska šake, mineralnom koštanom gustinom i metaboličkim sindromom. Analazirirana je i funkcija šake pomoću tri validirana upitnika: Michigan Hand Outcomes Questionnaire (MHQ, Duruoz Hand Indeks (DHI), Health Assessment Questionnaire (PROMIS HAQ). Statistička obrada podataka rađena je u programu SPSS verzija 25. REZULTATI: Prosečna starost pacijentkinja je bila 65,89±3,67 godina. Eksperimentalna i kontrola grupa se statistički razlikuju prema porodičnoj anamnezi o strukturnim promenama zglobova šaka, prema bolnosti šaka u miru, bolnosti šaka pri palpaciji, uzdržavanju od pokreta prstiju šaka, snage stiska šake, metaboličkom sindromu( p<0,001). Kao značajni prediktori za nastanak osteoartroze šaka su se izdvojili pozitivna porodična anamneza o strukturnim promenama za zglobovima šaka i metabolički sindrom ( p<0,001). Utvrđen je veći broj ispitanica sa normalnom koštanom gustinom u kontrolnoj grupi. Eksperimentalna grupa bolesnica imala je lošiju funkciju šake, odnosno lošiji skor primenom validiranih upitnika ( p <0,001). ZAKLJUČAK: Pacijentkinje sa izraženom osteoartrozom šaka imaju smanjenu funkciju šake, češći metabolički sindrom u odnosu na kontrolnu grupu, ali ne i značajno nižu koštanu gustinu.
INTRODUCTION: Arthritis of the hand is one of the most common musculoskeletal disorders. It manifests as pain, sometimes accompanied by swelling and deformities, which may lead to the loss of hand function. However, there is no consensus on the relationship between osteoarthritis (OA) and osteoporosis (OP) as the two most common skeletal disorders. AIMS: The study aim was to determine the risk factors related to the development of OA in the hand, as well as compare the bone density in patients with hand OA (HOA) with that measured in the control group and establish the significance of metabolic syndrome in the HOA group. MATERIAL AND METHODS: The study was conducted over a 12-month period and included a sample comprising of the experimental (patients affected by HOA) and the control (individuals with no evidence of HOA) group. HOA was diagnosed based on the reported pain, clinical evidence of hand deformities in postmenopausal women aged 60−70, and radiological evidence of physiological changes (Grade II to IV, based on the Kellgren-Lowrence scale). The risk factors for the development of HOA were analyzed, along with the link between HOA and hand grip strength, bone mineral density and metabolic syndrome. Analyses also included had function, as determined by three validated questionnaires: Michigan Hand Outcomes Questionnaire (MHQ), Duruoz Hand Index (DHI), and Health Assessment Questionnaire (PROMIS HAQ). Statistical analyses were performed using the SPSS version 25 computer software. RESULTS: The average age of the sample was 65.89±3.67 years. There were statically significant differences between the experimental and the control group with respect to the family history of structural changes in the hand joints, perceived hand pain at rest and when palpated, reluctance to utilize fingers, hand grip strength, and metabolic syndrome (p < 0.001). Family history of structural changes to the hand joints and metabolic syndrome emerged as the strongest predictors of the osteoarthritis of the hand development (p < 0.001). A greater number of the control group members had normal bone mineral density, while the patients assigned to the experimental group had inferior hand function, as determined by the score on the aforementioned validated questionnaires (p < 0.001). CONCLUSION: Postmenopausal women with pronounced osteoarthritis of the hand have reduced hand function, and are more likely to suffer from a metabolic syndrome relative to the control group, while the differences in bone mineral density are not statistically significant.

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Ezzat, Allison Mairi. "Cumulative occupational physical load as a risk factor for knee osteoarthritis in men and women." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43108.

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Objective: To determine the association between cumulative occupational physical load (COPL) to the knee and the presence of symptomatic osteoarthritis (SOA) and magnetic resonance imaging–defined osteoarthritis (MRI-OA). Methods: Cross-sectional analyses of symptomatic and asymptomatic (n=327) individuals were performed. Inclusion criteria for the symptomatic participants were: 1) having pain, aching, or discomfort in or around the knee on most days of the month at any time in the past; 2) having any pain, aching, or discomfort in or around the knee in the past 12 months. Asymptomatic participants responded “no” to both knee pain questions. COPL was calculated using a self-reported level of activity (five levels) and participation in knee bending/kneeling tasks (three levels) for each occupation held. SOA was defined by the Kellgren Lawrence x-ray grade ≥2, plus the presence of knee pain, as defined by the study inclusion pain criteria. MRI-OA was defined using the criteria specified by Hunter and associates. Logistic regression analyses, adjusted with population weights, were used to examine the associations between COPL (reference group=the lowest COPL quarter) and the presence of SOA and MRI-OA, respectively, after controlling for age, female sex, body mass index, and two-way interactions. Results: Participants (women=167, men=160) were on average 58.5 (SD=11.0) years old with a BMI of 26.3 (SD=4.7). Of those, 102 (31.2%) participants had SOA. For SOA, a monotonic statistically significant relationship was found between COPL 4 (highest quarter; odds ratio (OR)=8.16; 95% CI=1.89, 35.27) and COPL 3 (OR=5.73; 95% CI=1.36, 24.12) versus COPL 1. For MRI-OA, monotonic and statistically significant associations were found in COPL 4 versus 1 (OR=9.54; 95% CI=2.65, 34.27); COPL 3 versus 1 (OR=9.04; 95% CI=2.65, 30.88); COPL 2 versus 1 (OR=7.18; 95% CI=2.17, 23.70). Conclusion: COPL is a significant risk factor for knee OA. Dose response relationships between COPL and both SOA and MRI-OA were found. This study provides new insight into the role of occupation in knee OA, although the results should be interpreted cautiously due to limitations associated with the cross-sectional study design.

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Calvet, Fontova Joan. "Relació dels factors de risc cardiovasculars clàssics, la síndrome metabòlica i les adipoquines amb l'artrosi de genoll; implicacions en severitat clínica." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/400764.

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L’artrosi és una malaltia plurifactorial. En els darrers anys s’ha relacionat tant amb els factors de risc cardiovasculars clàssics com amb fenòmens d’inflamació, canviant el paradigma de la malaltia. En el primer treball s’avalua l’associació de l’artrosi simptomàtica de mans o genolls amb els factors de risc cardiovasculars clàssics i la síndrome metabòlica respecte un grup control. Es realitza una aproximació a la definició de síndrome metabòlica, donat es tracta d’un estudi transversal observacional. S’observa que tant l'obesitat com la hipertensió arterial són més freqüents en el grup de pacients amb artrosi. Igualment aquests pacients tenen una major presència de síndrome metabòlica. Quan es comparen els episodis cardiovasculars, el grup amb artrosi presenta un major nombre, però l’artrosi, tot i ser influent, no esdevé un factor de risc independent per la seva aparició. Es conclou que els pacients amb artrosi tenen una freqüència augmentada de factors de risc cardiovasculars i síndrome metabòlica. En el segon treball es valora un grup homogeni de pacients amb artrosi de genoll, donades quatre característiques peculiars. La primera és que totes són dones. La segona, totes les pacients presenten artrosi de genoll amb vessament associat. La tercera és que totes tenen elevats índex simptomàtics per dolor i/o discapacitat funcionals a nivell del genoll, i en darrer lloc, les pacients es distribueixen en els diferents graus d’afectació radiològica a diferència d’altres estudis on només s’avaluen pacients en estadi final protèsic. En aquest grup de pacients, es pretenia avaluar la relació dels factors de risc cardiovascular, la síndrome metabòlica i les adipoquines en líquid articular amb la severitat clínica de l’artrosi de genoll, valorada per un qüestionari que presenta dominis tant de dolor com de capacitat funcional com és l’índex de Lequesne. Com a variables de control s’utilitzen el grau d’afectació radiològic, la realització d’exercici físic, marcadors clàssics de la inflamació com el factor de necrosi tumoral, i mesures antropomètriques com el perímetre de cintura. Es determinen set adipoquines en líquid articular, leptina, adiponectina, resistina, osteopontina, visfatina, omentina i quemerina. Els nostres resultats mostren una associació significativa entre la leptina, la resistina i l’osteopontina amb la severitat clínica en artrosi de genoll amb vessament. De tota manera quan s’avalua aquesta associació sota l’efecte de les variables de confusió i de totes les adipoquines, només la resistina s'associa de forma directa i significativa amb l’índex de Lequesne, mentre que la visfatina mostra una associació significativa i inversa amb la severitat clínica. Entre les variables de confusió, el perímetre de cintura i el grau d’afectació radiològica tenen també una associació significativa i independent amb la severitat clínica, mentre que la realització d’exercici físic es relaciona de forma inversa i independent amb l’índex de Lequesne. Els nostres resultats mostren una associació entre diferents adipoquines en líquid articular i la severitat clínica, evidenciant la influència de factors proinflamatoris en l’artrosi de genoll, però també posen de manifest la presència de possibles interaccions biològiques entre les diferents adipoquines respecte la gravetat clínica, donat que les diferents associacions poden variar en funció de les adipoquines avaluades.
Osteoarthritis is a multifactorial disease. In last few years, ostearthritis has been related to classical cardiovascular risk factors and to inflammatory features, leading to a conceptual change of the disease. The first work was addressed to evaluate the association between symptomatic knee or hand osteoarthritis with cardiovascular risk factors and metabolic syndrome versus a control group. Due to the transversal design of the study, an approximation to the definition of metabolic syndrome was made. Patients with osteoarthritis had a high frequency of obesity, hypertension and metabolic syndrome. Unless the number of cardiovascular events was higher in the osteoarthritis group, no significant statistical differences were found, and although osteoarthritis had an influence, it was not independently associated to the presence of cardiovascular events. We concluded that patients with osteoarthritis had a high frequency of cardiovascular risk factors and metabolic syndrome. The second work was carried out in a homogeneous group of knee osteoarthritis with four disctintive features. First, all patient were women. Second, all patient had synovial effusion at the moment of evaluation. Third, the symptomatic levels regarding knee pain or disability were high. Lastly, patients were not in a final radiographic stage and the study was not addressed to patients who underwent prosthetic surgery. We aimed to assess the association between clinical severity with cardiovascular risk factors, metabolic syndrome and synovial fluid adipokines. Clinical severity was evaluated with the Lequesne index, which included pain and disability questions. The confusion factors assessed included radiological degree, physical exercise, classical inflammatory markers like tumour necrosis factor alpha, and anthropometric measurements like waist circumference. Seven adipokines in synovial fluid were determined (leptin, adiponectin, resistin, osteopontin, visfatin, omentin and chemerin). Our results showed a significant association between leptin, resistin and ostepontin with clinical severity in patients with knee osteoarthritis and joint effusion. When the association was evaluated with all confounders and all adipokines, only resistin was associated independently and directly to the Lequesne index, while visfatin was inversely and independently related to clinical severity. Between confounders, waist circunference and radiographic degree were independently and directly associated to clinical severity, while physical exercise was independently and inversely related to Lequesne index. An association between different adipokines and clinical severity was shown in our study, so proinflammatory factors in synovial fluid are important in the clinical evaluation of knee osteoarthritis. Another highlighted point derived from our results were the biological interactions between adipokines regarding knee osteoarthritis clinical severity, because the adipokine association may change depending on which of them were evaluated. This, in our opinion, is an important point for future studies.

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Yang, Yating, and 楊雅婷. "Potential Risk Factors Associated with Hand Osteoarthritis in Taiwan." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/56151486670129243766.

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碩士
國立臺北大學
統計學系
101
The aging problem is become a global problem. Once people in middle age, the physical function will gradually degenerate, and the occurrence of all chronic diseases or other aging diseases will increase apparent. Thus, the impact of the aging world should be studied more carefully. Osteoarthritis, also known as degenerative Joint Disease, is one of the most troublesome diseases among all of the most common elderly diseases. It not only induces pain constantly, but also causes the physical movement uncomfortably. Up to now, hand osteoarthritis disease symptoms and the patients’ own situation are studied rarely by researches studied osteoarthritis in Taiwan. If osteoarthritis can be diagnosed earlier by the clinical observation, it can effectively avoid the subsequent pain symptoms, possible loss of the physical function and even disability. This study utilized the data from Genome-Wide Study for Disease Susceptibility Genes in Patients with Hand Osteoarthritis (HOA) of the Han-Chinese Population involving a collection of eight hospitals. 497 eligible participants were classified into three groups. There were 182 participants who had hand osteoarthritis, and 115 participants who were treated as a disease control group and a normal control group of 200 participants. The demographics of participants, the family’s ancestral history and related disease history, profession and lifestyle, the medical history and drug history, the clinical physical examination, the clinical physical assessment, the grip strength, and pinch strength measurements were collected. Many clinical variables were grouped into many constructs established by the factor analysis and reliability analysis. The chi-square and Kruskall Wallis test were used to assess the association between the categorical variable and the continuous explanatory variable and the classification of the participants. The overall association between associated clinical variables and the classification of participants were assessed by the multinomial logit model. Age at screening, weight, finger joints swollen, gender, hospital classification have the greatest influence in predicting the classification of participants. More specifically, the study shows that people with swelling on finger joints suffer higher probability of hand osteoarthritis, and older age is an important risk of hand osteoarthritis. The results of this study provide clinical preliminary judgment in hand osteoarthritis. The health agencies can use such information to develop health policy in this area. As a result, people can effectively prevent from suffering hand osteoarthritis or reduce the risk having this disease.

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Книги з теми "Osteoarthritis Risk factors"

Prescott, Vanessa. A picture of osteoarthritis in Australia. Canberra: Australian Institute of Health and Welfare, 2007.

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Prescott, Vanessa. A picture of osteoarthritis in Australia. Canberra: Australian Institute of Health and Welfare, 2007.

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Doherty, Michael. Osteoarthritis. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0266.

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Osteoarthritis (OA) is a disorder of synovial joints and is characterized by the combination of focal hyaline cartilage loss and accompanying subchondral bone remodelling and marginal new bone formation (osteophyte). It has genetic, constitutional, and environmental risk factors and presents a spectrum of clinical phenotypes and outcomes. OA commonly affects just one region (e.g. knee OA, hip OA). However, multiple hand interphalangeal joint OA, usually accompanied by posterolateral firm swellings (nodes), is a marker for a tendency towards polyarticular ‘generalized nodal OA’.

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Abhishek, Abhishek, and Michael Doherty. Epidemiology and risk factors for calcium pyrophosphate deposition. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0048.

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Calcium pyrophosphate crystal deposition (CPPD) is rare in younger adults but becomes increasingly common over the age of 55 years, especially at the knee. Ageing and osteoarthritis (OA) are the main attributable risk factors. Hyperparathyroidism, hypomagnesaemia, haemochromatosis, and hypophosphatasia are other less common risk factors. Rare families with familial CPPD have been reported from many different parts of the world, and mainly present as young-onset polyarticular CPPD. Recent studies suggest that CPPD occurs as the result of a generalized constitutional predisposition and may also associate with low cortical bone mineral density. Previous meniscectomy, joint injury, and constitutional knee malalignment are local biomechanical risk factors specifically for knee chondrocalcinosis. Although associated with OA, current evidence suggests that CPPD does not associate with development or progression of OA.

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Vincent, Tonia L., and Linda Troeberg. Pathogenesis of osteoarthritis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0138.

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Understanding pathogenic mechanism in disease is critical for development of targeted therapeutic strategies. Although there are, at this time, only a handful of experimental approaches for treating osteoarthritis (OA), until 10 years ago this disease was almost universally considered an unmodifiable condition. Emerging data during this time, largely fuelled by studies in rodent models, has completely changed the paradigm of disease pathogenesis and has for the first time, generated novel, realistic targets for this highly prevalent and disabling condition. These targets include the aggrecanases, members of the ADAMTS family, and collagenases, which together are critical for the early breakdown of the extracellular matrix of cartilage. Some recent success has also been demonstrated by targeting bone in disease. Development of pain in OA is complex and likely arises from different tissues at different stages of disease. In the following section we describe the pathological features of OA, and discuss the evolution of theories of OA pathogenesis and factors that have limited mechanistic clarity in this disease. We summarize the molecular pathways that are now known to be active in disease, and consider how these identified molecular pathways could be linked to known epidemiological risk factors. We finish by discussing possible future therapeutic strategies that will emerge from these discoveries and the current limitations in implementing new therapies in OA.

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Doherty, Michael, Johannes Bijlsma, Nigel Arden, David J. Hunter, and Nicola Dalbeth. Introduction: what is osteoarthritis? Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0001.

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This brief introductory chapter summarizes some of the key clinical and structural features of osteoarthritis (OA) and highlights some general observations and concepts concerning the nature of OA. General observations include the preservation of OA throughout human evolution; the occurrence of OA in many other animals; the dynamic, metabolically active nature of OA pathophysiology; the fact that most OA never associates with symptoms or functional impairment; and the good outcome in many cases of symptomatic OA. Such observations support the concept of OA as the inherent repair process of synovial joints, which can be triggered by a range of diverse insults and in which all the joint tissues are involved. Aetiologically, OA is a common complex disorder with recognized genetic, constitutional, and environmental risk factors, and these may combine in multiple ways to cause marked variation in phenotypic presentation and in some instances ‘joint failure’ with associated symptoms and disability. Within the spectrum of OA are some discrete subsets, the best defined being nodal generalized OA. However, in many people OA does not fit neatly into one type and its phenotypic characteristics may change as it evolves. Two striking associations of OA are with ageing and with crystal deposition, especially calcium crystals but also urate crystals, and there are a number of possible mechanisms to explain these.

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Doherty, Michael, David J. Hunter, Hans Bijlsma, Nigel Arden, and Nicola Dalbeth, eds. Oxford Textbook of Osteoarthritis and Crystal Arthropathy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.001.0001.

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The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. There are also new in-depth sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning.

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L, Sutton Amy, ed. Arthritis sourcebook: Basic consumer health information about the risk factors, symptoms, diagnosis, and treatment of osteoarthritis, rheumatoid arthritis, juvenile arthritis, gout, infectious ... 3rd ed. Detroit, MI: Omnigraphics, 2010.

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Dekker, Joost, Daniel Bossen, Jasmijn Holla, Mariëtte de Rooij, Cindy Veenhof, and Marike van der Leeden. Psychological strategies in osteoarthritis of the knee or hip. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0025.

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Characteristic clinical presentations of osteoarthritis (OA) include pain and activity limitations. These presentations are dependent on psychological processes. The literature reviewed in this chapter leads to the following conclusions: (1) symptoms of depression, anxiety, and fatigue are more prevalent among patients with OA than among the general population. Recently, a depressive mood phenotype has been identified in knee OA. (2) Symptoms of depression, anxiety, and fatigue, as well as other psychological variables are established risk factors for future worsening of pain and activity limitations. (3) Psychological interventions such as depression care and pain coping skills training have been demonstrated to improve pain and activity limitations, as well as psychological outcomes. Self-management may have beneficial effects, although there is clearly room for improvement. Interventions combining psychological interventions with exercise therapy have been shown to be effective; improved outcome over exercise therapy alone stills needs to be demonstrated. (4) Psychological interventions are effective in improving exercise adherence and promoting physical activity. Overall, it can be concluded that the psychological approach towards OA is fruitful: the psychological approach has resulted in substantial contributions to the understanding and management of clinical presentations of OA, including pain and activity limitations.

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Runhaar, Jos, and Sita M. A. Bierma-Zeinstra. Lifestyle. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0012.

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Modern lifestyles put a great burden on the human musculoskeletal system. Since 1980, the worldwide prevalence of obesity has tripled in many European countries. Obesity is known to affect both weight-bearing and non-weight-bearing joints due to a combination of mechanical overload and systemic inflammation. On the other hand, both to combat the obesity pandemic and to increase or maintain the quality of life, physical activity and sports are encouraged next to a healthy diet. Although both have a positive influence on cardiovascular risk factors, physical activity and especially sporting activities do lead to increased loading of the active joints and increased risk for joint injuries, which might lead to osteoarthritis development. This chapter provides an overview of the current knowledge on lifestyle risk factors for the development and progression of osteoarthritis as published in recent systematic reviews, complemented with several narrative reviews.

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Частини книг з теми "Osteoarthritis Risk factors"

Bialog, Crisostomo, and Anthony M. Reginato. "Epidemiology, Risk Factors, and Aging of Osteoarthritis." In Geriatric Rheumatology, 173–85. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-5792-4_18.

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Rodríguez-Merchán, E. Carlos, Hortensia De la Corte-Rodríguez, and Carlos A. Encinas-Ullán. "Peroneal Nerve Palsy After Total Knee Arthroplasty: Prevalence, Risk Factors, Diagnosis and Management." In Comprehensive Treatment of Knee Osteoarthritis, 135–42. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44492-1_13.

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van der Leeden, Marike, Cindy Veenhof, Leo D. Roorda, and Joost Dekker. "Risk Factors for Functional Decline in Osteoarthritis of the Knee or Hip." In Exercise and Physical Functioning in Osteoarthritis, 39–48. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7215-5_4.

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Yamazaki, Junya, and Lars Engebretsen. "Anterior Cruciate Ligament Surgery: Risk Factors for Development of Osteoarthritis: What Can We Do to Prevent It?" In The ACL-Deficient Knee, 41–48. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-4270-6_4.

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Alexos, Antonios, Serafeim Moustakidis, Christos Kokkotis, and Dimitrios Tsaopoulos. "Physical Activity as a Risk Factor in the Progression of Osteoarthritis: A Machine Learning Perspective." In Lecture Notes in Computer Science, 16–26. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53552-0_3.

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Hashmi, Syed Musab. "Chapter-04 Risk Factors in Osteoarthritis." In Step by Step� Treatment of Osteoarthritis Knee, 41–56. Jaypee Brothers Medical Publishers (P) Ltd., 2011. http://dx.doi.org/10.5005/jp/books/11230_4.

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Barr, Andrew J., and Philip G. Conaghan. "Osteoarthritis." In Oxford Textbook of Medicine, edited by Richard A. Watts, 4470–81. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0450.

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Clinical osteoarthritis (OA) is a syndrome of joint pain associated with structural deterioration of synovial joints that over time involves the whole joint organ. It is the most common form of arthritis and a leading cause of chronic pain, disability, and socioeconomic burden. Affected individuals report pain (especially on weight bearing) and joint stiffness leading to loss of muscle strength and poor joint function. This results in reduced participation in valued activities, low mood, sleep disturbance, and poor quality of life. The aetiology of joint deterioration, pain, and the interaction of the two remains unclear. OA is associated with a variety of both modifiable and non-modifiable risk factors including obesity, age, gender, occupational injury, trauma, and genetic predisposition. Obesity is the strongest potentially modifiable risk factor.

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Blanco, Francisco J. "Osteoarthritis." In Oxford Textbook of Geriatric Medicine, 553–62. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198701590.003.0072.

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Osteoarthritis (OA) is the most common joint disease related to ageing involving cartilage degradation, synovial inflammation, subchondral bone sclerosis, degeneration of ligaments and, in the knee, the menisci and hypertrophy of the joint capsule. Other alterations, in periarticular muscles, nerves, bursa, and local fat pads, also contribute to OA. Some risk factors are associated with OA and it is possible to differentiate between risk factors that confer a generalized susceptibility to OA, such as age, osteoporosis, heredity, and gender, and the differing local biomechanical factors of joints, such as trauma, anatomical variance of the articulation, occupational exposures, and obesity. The treatment of osteoarthritis should be individualized and adjusted to the joint affected. The objectives are to control pain, maintain function, and to slow progression. Treatment of OA can be considered in symptom-modifying and structure-modifying treatments.

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Keenan, Anne-Maree, and Shannon Munteanu. "Osteoarthritis." In The Foot and Ankle in Rheumatology, 53–66. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198734451.003.0004.

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In this chapter, we will cover osteoarthritis. First we will provide an overview, with definitions, pathogenesis and risk factors, and clinical features, followed by recommendations for holistic management of the disease. A detailed discussion on the prevalence and impact of foot disease is then given, by area of the foot. Specific non-pharmacological and pharmacological management are described, and surgical options are outlined. Finally, clinical trials and the future direction of research are covered.

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Zhang, Yuqing, and Sita M. A. Bierma-Zeinstra. "Diagnosis, risk factors for OA development and progression, OA prevention, and recognizing comorbidities." In Osteoarthritis Health Professional Training Manual, 39–53. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-99269-5.00005-0.

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Тези доповідей конференцій з теми "Osteoarthritis Risk factors"

Doherty, M. "SP0005 Risk factors for osteoarthritis." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.27.

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Melikoglu, M. Alkan, and A. Kul. "AB0809 Fall risk and related factors in knee osteoarthritis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.3072.

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Alekseeva, L., S. Anikin, N. Kashevarova, E. Sharapova, E. Taskina, T. Korotkova, T. Raskina, et al. "FRI0545 Risk factors predicting radiological progression of knee osteoarthritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.2089.

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Oladejo, R. A., and B. T. Achori. "Development of a Risk-Factor Model for Predicting Occurrence of Knee Osteoarthritis." In 27th iSTEAMS-ACity-IEEE International Conference. Society for Multidisciplinary and Advanced Research Techniques - Creative Research Publishers, 2021. http://dx.doi.org/10.22624/aims/isteams-2021/v27p40.

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This study identified the required risk factors for Knee Osteoarthritis (KOA) patients and formulated a predictive model based on the identified variables. Extensive review of related work was done so as to understand the body of knowledge surrounding musculoskeletal related diseases and to identify knee osteoarthritis as one of the diseases under musculoskeletal condition as well as elicit the risk factors for it, these were validated from medical experts. The model to forecast knee osteoarthritis was formulated comparing four supervised machine learning algorithms namely Naïve Bayes, Multilayer perceptron, C4.5 Decision Tree and Support Vector Machine. The result of the model showed an accuracy of 97.59% considering the 36 initially identified attributes using no feature selection method, the results also showed the minimum number of variables relevant for knee osteoarthritis condition. Further results showed that all identified variables are relevant for effective and efficient development of a prognostic model for knee osteoarthritis. The study concluded that age as the most important variable for KOA and that all 36 identified attributes are relevant for predicting the risk of KOA. Keywords: Knee osteoarthritis, Prognostic Model, Machine learning.

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Aydoğdu, O., Z. Sarı, US Yurdalan, and GM Polat. "SAT0743-HPR Risk factors for fear of falling in patients with knee osteoarthritis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.5714.

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Vladimirov, S., M. Eliseev, O. Zhelyabina, and M. Chikina. "SAT0369 Comparison of risk factors for cardiovascular diseases in pts with cppd gout and osteoarthritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5693.

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Manlapaz, D. G., P. Jayakaran, G. Sole, and C. M. Chapple. "SAT0738-HPR Factors associated with risk of falling in adults with knee osteoarthritis: a cross-sectional study." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.4388.

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Flugsrud, GB, B. Espehaug, LI Havelin, L. Nordsletten, and HE Meyer. "OP0123 Body mass index and physical activity as risk factors for primary osteoarthritis. a cohort study in 50.034 persons." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.783.

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Zhu, Z., W. Han, S. Zheng, K. Wang, T. Winzenberg, F. Cicuttini, C. Ding, and G. Jones. "THU0647 Interactions between steps per day and risk factors for osteoarthritis on mri-detected osteophytes in a population based cohort study." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.1162.

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Skousgaard, Søren, Søren Møller, Axel Skytthe, Prof Søren Overgaard, and Lars Peter Andreas Brandt. "308 Occupational risk factors for hip and knee osteoarthritis – evidence of gene-exposure interaction: a co-twin control study in danish twins." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.748.

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Звіти організацій з теми "Osteoarthritis Risk factors"

Huang, XiMeng, ZeXi Yang, and Ying Huang. Lateral Wedge Insoles for Reducing Biomechanical Risk Factors for Medial Knee Osteoarthritis after a period of time: a meta-analysis of controlled randomized trials. INPLASY - International Platform of Registered Systematic Review Protocols, March 2020. http://dx.doi.org/10.37766/inplasy2020.3.0015.

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Huang, Xi-Meng, Ze-Xi Yang, and Ying Huang. Physical Therapy and Orthopedic Equipment-induced Reduction in the Biomechanical Risk Factors Related to Knee Osteoarthritis: a Bayesian network meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2020. http://dx.doi.org/10.37766/inplasy2020.9.0054.

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A. Komnos, Georgios, Antonios Papadopoulos, Efstratios Athanaselis, Theofilos Karachalios, and Sokratis E. Varitimidis. Migrating Periprosthetic Infection from a Total Hip Replacement to a Contralateral Non-Operated Osteoarthritic Knee Joint. Science Repository, January 2023. http://dx.doi.org/10.31487/j.ijscr.2022.03.02.

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Анотація:

Introduction: There is a paucity of published data on whether a treated infected arthroplasty is a risk factor for infection in another, non-operated joint. Contamination of a primary, arthritic, non-operated joint from an infected arthroplasty is a relatively rare entity. Case: We report a case of migration of a pathogen (Enterococcus faecalis) from an infected prosthetic joint (hip) to the contralateral native joint (knee). Identification of the pathogen was made with PCR, by obtaining cultures during the implantation of the primary knee prosthesis. Conclusion: Contamination of a primary, arthritic, non-operated joint from an infected arthroplasty has not been widely reported. Management of such cases is extremely challenging and without clear and established guidelines. Our experience shows that tissue samples should be taken intraoperatively and sent for cultures, so as to exclude contamination in those cases.

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