Готові списки джерел за темами / Organ Transplant Recipient

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Добірка наукової літератури з теми "Organ Transplant Recipient"

Автор: Grafiati
Опубліковано: 11 березня 2023

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Статті в журналах з теми "Organ Transplant Recipient"

1

Samraj, Annie N., Ryan Morse, Niklas Krumm, Monica B. Pagano, John R. Hess, and Hamilton Tsang. "Genetic Testing to Resolve the Source of Hemolytic Antibody in Solid Organ Transplantation." American Journal of Clinical Pathology 152, Supplement_1 (September 11, 2019): S4. http://dx.doi.org/10.1093/ajcp/aqz112.007.

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Анотація:
Abstract Introduction Antibody-mediated hemolysis arising in the face of solid organ transplant can be devastating. Some degree of passenger lymphocyte syndrome is said to occur in up to 10% of ABO mismatched renal transplants, 40% of ABO mismatched liver transplants, and 70% of ABO mismatched heart-lung transplants, a reflection of the number of memory B-cells transplanted with the organ. Passenger lymphocyte syndrome is less common with minor antigens but can still be severe. Materials and Methods A series of patients developed immune hemolytic anemia after solid organ transplantation. Conventional serologic testing was performed using tube and solid-phase testing. Molecular testing was performed using gene-chip array. Results In patients receiving a minor antigen mismatched organ transplant and multiple allogenic red cell transfusions, serologic methods proved insufficient to resolve the source of minor blood group antibodies that arose in the aftermath of transplant. Genetic testing was able to clearly resolve donor and recipient types. Conclusions Passenger lymphocyte syndrome after mismatched organ transplantation is not rare. The mixtures of organ donor, recipient, and other transfused RBCs profoundly limit the usefulness of serologic testing. Genetic assignment of minor blood types to donor and recipient can guide therapy and inform prognosis.
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2

Borović, Vladan, Saša Borović, Vida Drąsutė, and Dejan Rančić. "SECURE ORGAN TRANSPLANT INFORMATION SYSTEM." Facta Universitatis, Series: Automatic Control and Robotics 17, no. 1 (November 26, 2018): 1. http://dx.doi.org/10.22190/fuacr1801001b.

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Анотація:
The heart of a modern and efficient information system is a computer database that can be accessed from all over the world. The system demands a strong protection and cryptography, due to a large number of threats in the electronic era. In the well organized transplant programs, all transplantation centers have access to the central computer database. In this important database, the transplantation centers enter information of their recipients along with the recipient profile and the donor profile. This is the basic principle of making the best match between donated organ and recipient. This paper elaborates the SetNet information system with potential criminal activities and malpractice regarding central computer database.
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3

Coleman-Musser, Lori, Kristine Nelson, and Roger Durand. "Discard Rates and Transplant Outcomes in Organs Recovered from Older Donors." Journal of Transplant Coordination 7, no. 4 (December 1997): 190–94. http://dx.doi.org/10.1177/090591999700700406.

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The number of donors aged 60 years and over has increased. This study examined discard rates and transplant outcomes in organs recovered from older donors. Data were obtained using a standard tool for donors aged 60 years and older during 1993 and 1994 and included demographics, medical history, use of vasopressors, renal/liver function studies, organ disposition, biopsy findings, and recipient organ function. Of 58 kidneys recovered, 24 were transplanted, 26 were used for research, and 8 were discarded. Of 14 livers recovered, 11 were transplanted, 1 was used for research, and 2 were discarded. Sixty-three percent of kidney recipients had immediate function; 79% at 30 days. Nine liver recipients had immediate function; 6 at 30 days, with 1 graft lost. Results show that kidneys and livers can be transplanted from older donors with positive outcomes. Factors such as medical history, use of vasopressors, and organ function studies may help predict organ disposition and function.
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4

Suddaby, Elizabeth C., Margaret J. Schaeffer, Lori E. Brigham, and Timothy R. Shaver. "Analysis of Organ Donors in the Peripartum Period." Journal of Transplant Coordination 8, no. 1 (March 1998): 35–39. http://dx.doi.org/10.1177/090591999800800108.

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This study was a retrospective review of 252 brain-dead potential donors from 1990 to 1996, including 5 organ donors in the peripartum period. The purpose of the study was to determine the effects of pregnancy on organ donor management and recipient outcome. Case analysis of 5 pregnant donors identified problems with hemodynamic stability and electrolyte abnormalities, including hypernatremia, hyperchloremia, and hypocalcemia. In addition, blood glucose was frequently elevated. Two donors were treated for diabetes insipidus. All 5 donors produced organs for 20 transplant recipients. Five heart recipients (including 1 heart-lung), 4 liver recipients, 4 kidney recipients, and 4 pancreas-kidney recipients have reported excellent outcomes. The use of organs from brain-dead organ donors in the peripartum period has minimal impact on donor management and recipient outcome.
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5

Mathes, David, Scott Stoll Graves, George E. Georges, Christian Kuhr, Jeff Chang, Tiffany Butts, and Rainer Storb. "Long-Term Tolerance to Kidney Allografts After Induced Rejection of Donor Hematopoietic Chimerism in a Preclinical Canine Model." Blood 120, no. 21 (November 16, 2012): 2991. http://dx.doi.org/10.1182/blood.v120.21.2991.2991.

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Abstract Abstract 2991 Allogeneic hematopoietic cell transplantation provides a reliable method for inducing tolerance towards solid organ grafts. However, this procedure can result in graft-versus-host disease (GVHD) thereby limiting its application. Here we test the hypothesis that mixed chimerism can be intentionally reverted to host hematopoiesis without rejection of a kidney graft. Recipient dogs were given 2 Gy total body irradiation (TBI) before and a short course of immunosuppression after marrow infusion from dog leukocyte antigen-identical littermates. All dogs achieved stable mixed chimerism. After a mean of 20 weeks, one cohort of dogs received kidney transplants from their respective marrow donors. Subsequently, recipients were reconditioned with 2 Gy TBI and given autologous granulocyte-colony stimulating factor-mobilized leukocytes (recipient leukocyte infusion) that had been collected before marrow transplant. Dogs receiving a second TBI and recipient leukocyte infusion without a kidney transplant rejected their donor hematopoietic graft within 3 weeks. Dogs that received kidney grafts, followed by a second TBI and recipient leukocyte infusion, rejected their marrow graft without rejecting their transplanted kidneys for periods greater than one year. Mixed chimerism may be clinically reverted to 100% recipient without rejection of a kidney allograft. This model has potential applications in understanding the mechanism of split tolerance. This finding may have application towards minimizing the risk of GVHD in solid organ transplant patients given hematopoietic cell transplantation from HLA-identical donors. Disclosures: No relevant conflicts of interest to declare.
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6

Lalwani, Jaya, Lokesh Kumar, Rameshwar ., and Jagadeesan M. "A rare case of mucormycosis in heart transplantation." International Journal of Advances in Medicine 9, no. 11 (October 26, 2022): 1143. http://dx.doi.org/10.18203/2349-3933.ijam20222671.

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Mucormycosis is the third most common invasive fungal infection with a high mortality rate seen in immunocompromised patients. It is an increasingly well-reported invasive fungal infection that affects recipients of solid-organ transplant. The incidence of mucormycosis in patients with heart transplants ranges from 0 to 0.6%. We reported a case of mucormycosis in a young heart transplant male recipient.
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7

Rao, Nitesh N., Chris Wilkinson, Mark Morton, Greg D. Bennett, Graeme R. Russ, Patrick T. Coates, and Shilpa Jesudason. "Successful pregnancy in a recipient of an ABO-incompatible renal allograft." Obstetric Medicine 12, no. 1 (March 7, 2018): 42–44. http://dx.doi.org/10.1177/1753495x17745390.

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Kidney transplantation restores fertility in patients with end-stage renal disease, with many successful pregnancies after kidney transplantation being reported. However, there are little data regarding pregnancy in women transplanted under modern-era desensitisation protocols that utilise rituximab, plasma exchange and intravenous immunoglobulin, including ABO-incompatible transplants. Pregnancies in ABO-incompatible recipients can pose new challenges from an immunological perspective. Here, we report a case of successful pregnancy using in vitro fertilisation, in a renal transplant recipient who underwent desensitisation two years prior, that included use of rituximab and plasma exchange to receive an ABO-incompatible transplant from her husband and subsequent father of the baby. We believe this was the first case of successful pregnancy after ABO-incompatible kidney transplantation in Australia and New Zealand. This case also highlights the difficulties faced in conception following transplantation and demonstrates that in vitro fertilisation utilising ovulation induction can be successfully utilised for conception in this cohort. This recipient also had gestational diabetes, worsening renal function and preterm delivery which are important complications often seen in pregnancies of solid organ transplant recipients.
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8

Stine, Jonathan G., Neeral Shah, and Curtis Argo. "Immunosuppressed Solid Organ Transplant Recipient." Gastroenterology 146, no. 2 (February 2014): 345–590. http://dx.doi.org/10.1053/j.gastro.2013.09.045.

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9

Rojas Vasquez, Marta, Anthea Peters, Raymond Lai, Curtis Mabilangan, Burton Catherine, and Jutta Preiksaitis. "Epidemiology of Post-Transplant Lymphoproliferative Disorders in Children with Solid Organ Transplant over 34 Years of a Single Center Experience." Blood 134, Supplement_1 (November 13, 2019): 1602. http://dx.doi.org/10.1182/blood-2019-125344.

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Background Post-Transplant lymphoproliferative disorders (PTLD) are a heterogeneous group of lymphoid neoplasms following solid organ transplantation (SOT) caused by uncontrolled lymphoproliferation often induced by Epstein Barr Virus (EBV) due to the lack of cytotoxic T cell response resulting from immunosuppression. A pre-emptive intervention strategy for PTLD prevention was implemented in our center in 2002 for all EBV-mismatched SOT recipients consisting in close monitoring of the viral load and consideration for early intervention (Ex; reduction of immunosuppression) in addition to universal antiviral prophylaxis (implemented in 1990). We aim to describe the incidence and risk factors for PTLD in children with SOT, including all transplant types, at a single center over 34 years. We also aim to analyze the impact of a pre-emptive PTLD prevention program. Material and methods All patients younger than 18 years of age who received SOT at the University of Alberta Hospital/Stollery Children's Hospital from January 1st, 1984 to December 31st, 2018 were included. Donor and recipient baseline data (age, sex, donor living status, date and type of transplant, EBV and cytomegalovirus serostatus) were extracted from a prospective database. Retrospective chart review was performed for PTLD cases along with expert pathology review (when tissue available). Local Ethics Board was obtained. Statistical analyses were performed using SPSS software version 25 and R version 3.3.3. Results Characteristics of the study population, immunosuppression regimen used by transplant program and specific immunosuppression for PTLD cases are summarized in table 1, 2 and 3 respectively. PTLD characteristics were compared based on the time of presentation of PTLD ≤1 year, 1 to 5 years and >5 years (table 4). Most of the cases with PTLD presented with primary involvement in multiple sites followed by lymph nodes, gastro-intestinal tract, allograft, tonsils/adenoids and other sites. Advance staging (III-IV) was present in 71% of cases. The incidence rate of PTLD for the whole group was 0.82/100 Person-year (Figure 1 A). The incidence rate peaked at 1-year post-transplant and had a decreasing trend in the following years post-transplant, with no cases beyond 12 years post-transplant (Figure 1 B). The cumulative incidence was the highest for the multi-visceral transplants followed by thoracic, liver and kidney transplants (Figure 1C). Univariate analysis showed children younger than 5 years at transplant had 5-fold higher risk of PTLD compared to children ≥ 10 years of age at transplant. Donors ≤ 5 years of age at transplant, showed 3-fold higher risk PTLD comparing to older donors. Liver transplant had 2.8-fold and thoracic transplants had 5-fold higher risk of PTLD comparing to kidney transplants, no significant risk was associated with multi-visceral group (only 1 case in the cohort). EBV seronegative recipient was associated with 2.6-fold higher risk of PTLD comparing to EBV seropositive recipient. Era prior to implementation of pre-emptive intervention had 3-fold risk of PTLD comparing to era post implementation. Patients transplanted at 1.1 - 5 years of age was an independent risk factor associated with PTLD in multivariate analysis (table 3) SOT recipients showed EBV seroconversion with age (Figure 3A). PTLD based on EBV Donor Recipient (DR) serostatus showed more cases D positive R negative (D+R-) in the first-year comparing to D negative Recipient negative (D-R-), D-R- cases increased between 1-5 years equivalent to D+R-, beyond 5 years D+R- decreased with no D-R- cases (Figure 3B). D-R- serostatus had the highest probability of PTLD followed by D+R- (Figure 3 C). Eleven (24%) out of 45 patients with PTLD presented with PTLD relapse. Seven (5.6%) out of 125 deaths of SOT were secondary to PTLD. PTLD was the most common cause of death in the PTLD group (50%) followed by graft failure/rejection. Conclusions Incidence of PTLD peaked in the first-year post-transplant and decreased overtime with increase incidence in thoracic and multi-visceral transplants. Risk factors for PTLD included patients transplanted at younger age, younger donors, thoracic and liver transplants and EBV seronegativity in the recipient. A pre-emptive intervention strategy for PTLD prevention implemented in 2002 decreased the risk of PTLD. Disclosures No relevant conflicts of interest to declare.
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Nambiar, Puja H., Brianna Doby, Aaron A. R. Tobian, Dorry L. Segev, and Christine M. Durand. "Increasing the Donor Pool: Organ Transplantation from Donors with HIV to Recipients with HIV." Annual Review of Medicine 72, no. 1 (January 27, 2021): 107–18. http://dx.doi.org/10.1146/annurev-med-060419-122327.

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Анотація:
Implementation of the HIV Organ Policy Equity (HOPE) Act marks a new era in transplantation, allowing organ transplantation from HIV+ donors to HIV+ recipients (HIV D+/R+ transplantation). In this review, we discuss major milestones in HIV and transplantation which paved the way for this landmark policy change, including excellent outcomes in HIV D–/R+ recipient transplantation and success in the South African experience of HIV D+/R+ deceased donor kidney transplantation. Under the HOPE Act, from March 2016 to December 2018, there were 56 deceased donors, and 102 organs were transplanted (71 kidneys and 31 livers). In 2019, the first HIV D+/R+ living donor kidney transplants occurred. Reaching the full estimated potential of HIV+ donors will require overcoming challenges at the community, organ procurement organization, and transplant center levels. Multiple clinical trials are ongoing, which will provide clinical and scientific data to further extend the frontiers of knowledge in this field.
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Більше джерел

Дисертації з теми "Organ Transplant Recipient"

1

Paris, Wayne. "Organ transplant recipient employment perception." Thesis, University of Huddersfield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430282.

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2

Falk, Rachel E. "Identity and adjustment : experiences of the organ transplant recipient." Thesis, Canterbury Christ Church University, 2015. http://create.canterbury.ac.uk/14079/.

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Анотація:
Positive health-related behaviour is particularly important for liver transplant recipients’ (LTRs) recovery. However, non-adherence in adolescents post-transplant is thought to be greater than, or equal to, 50%. Literature searches have found limited research into the area of young adults’ experiences of having a donated liver. Knowing more of their experience seems important to help inform practice to improve adherence and ultimately save lives. The present study aimed to construct a grounded theory of young adults’ experiences of having a liver transplant, in order to better understand how young adults may adjust following such experiences. Semi-structured interviews were conducted with twelve liver transplant recipients (LTRs; five female, seven male). Data were analysed using constructivist grounded theory. A model was constructed to capture the dynamic interactions between thirteen categories, resulting in four main themes: Finding Identity Post-Transplant, Carrying Responsibility, Unseen, Unspoken or Misunderstood Challenges and Adjusting to Life After Transplant. The study highlights the importance of the themes in psychological adjustment post-transplant. Understanding this process is imperative in order to improve health-related behaviours in a cohort with traditionally poor adherence. Implications for further research and clinical practice are discussed, including educating LTRs to raise their levels of self-efficacy, which have a positive impact on adherence.
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3

Evertsson, Elvira, and Åsa Dunder. "Organmottagares upplevelse av att ha genomgått en hjärttransplantation : En litteraturbaserad studie." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-16761.

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Анотація:
Bakgrund: I Sverige utfördes den första hjärttransplantationen år 1984 i Göteborg. En ökande trend har identifierats genom åren och Sverige är det land som utför flest hjärttransplantationer i Skandinavien. Det är vid svår hjärtsvikt som den drabbade kan bli kandidat för eventuell hjärttransplantation och sjuksköterskan har en nyckelroll i omvårdnaden av dessa patienter. Omvårdnadens syfte är att förbättra patientens chans för överlevnad och livskvalitet. Syfte: Beskriva organmottagares upplevelser av att ha genomgått en hjärttransplantation. Metod: En litteraturbaserad metod för att bidra till evidensbaserad omvårdnad med grund i analys av kvalitativ forskning. Resultat: Fyra kategorier identifierades; En ny livssituation, förändrad syn på livet, ta del av andra erfarenheter och nya tankar inför framtiden, med tio underkategorier. Konklusion: Resultatet visar att patienter som genomgått en hjärttransplantation upplever en förändrad vardag och livssyn. Nya insikter om livet och upplevelse av att fått en ny chans skapas. Detta väcker känsla av tacksamhet och skyldighet gentemot sin donator. Majoriteten av patienterna upplevde att stödet från sjukvården var bristfälligt, både inför och efter operationen och att det är bristen på information som upplevs som central.
Background: The first heart transplant performed in Sweden took place in 1984 in Gothenburg. An increasing trend has been identified over the years and Sweden is the country that performs most heart transplants in Scandinavia. It is in case of severe heart failure that the affected person can become a candidate for any heart transplant and the nurse has a key role in the care of these patients. The purpose of nursing is to improve the patient's chance of survival and quality of life. Aim: The aim was to describe the organ recipient’ experience after having a heart transplant. Method: A literature-based study where the data consisted of qualitative articles. Result: Four categories were identified; A new life situation, changed view of life, influence from others and new thoughts about the future with ten subcategories. Conclusion: The result shows that patients who have undergone a heart transplant experience a changed everyday life and belief. New insights about life and the experience of having a new chance created. This arouses a sense of gratitude and obligation towards their donor. The majority of the patients felt that the support from the health service was inadequate, both before and after the surgery and that it is the lack of information that is perceived as central.
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4

Totti, Valentina <1986&gt. "Exercise and sport for health in solid organ transplant recipients." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amsdottorato.unibo.it/9222/1/PhD%20Thesis%20Totti%20V..pdf.

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Is well known that physical activity reduces rate of cardiovascular and all-cause mortality in the general population and in transplanted recipients. However, most of those investigations present limits. Few data are available on exercise effectiveness on kidney and liver transplant recipients and the correlation between practising exercise, lipid profile and renal function. Additionally, the knowledge on the amount of safe training for sport competitions for this population is limited. This thesis aims to increase the knowledge on the type of exercise and training adapted for transplant recipients and its relative effects on aerobic capacity, strength and quality of life. Moreover, correlation between exercise and blood pressure parameters in solid organ transplant are considered for safeguard of the graft function. The first part of this thesis focuses on the effects of exercise in kidney and liver transplant recipients by health pathways. The second part focus on the sport in solid organ transplant recipients to break down the prejudice that “transplantation” and “sport” cannot coexist. In detail, we investigate the renal function, metabolic profile, glycemia and the physical fitness after 12 months of supervised aerobic and resistance training in kidney and liver transplant recipients, compared with not supervised home-based physical activity. The results of these studies can provide information on the beneficial effects of combined exercise and identify the type of safe exercise to prescribe for the kidney and liver transplant population. These indications are intended to encourage the healthcare world to refer pre-and post-transplant patients to follow a healthy lifestyle including regular exercise for the prevention of cardiovascular diseases. To obtain more adherence in the prescription of exercise in transplant patients a study promote the network in which transplant centers, sports medicine centers and certified gyms collaborate to encourage the practice of prescribed and controlled exercise in pre- and post-transplant patients.
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5

Mankowski, Sophie. "Personality predictors of post-transplant health outcomes in solid organ recipients." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0015/MQ37586.pdf.

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6

Humphrey, Heather. "Current Practices in Music Therapy with Bone Marrow and Organ Transplant Recipients." UKnowledge, 2016. http://uknowledge.uky.edu/music_etds/65.

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Анотація:
There is limited research on music therapy for transplant recipients, yet board-certified music therapists working in medical settings often encounter individuals from the transplant population. The purpose of this study was to examine the current practices of music therapists working with bone marrow and organ transplant recipients. A total of 68 board-certified music therapists completed an online survey, providing information related to goal areas addressed in music therapy sessions and interventions frequently used with bone marrow and organ transplant patients. The most frequently reported goal areas included: coping skills, mood, and self-expression. The most frequently reported interventions included: singing, songwriting, and improvisation. Survey respondents also shared opinions related to the need for additional resources for music therapists working with transplant recipients, as well as the most rewarding and challenging aspects of working with transplant patients. Study limitations, suggestions for future research, and implications for clinical practice are included.
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7

Haque, Tanzina. "Longitudinal study on Epstein-Barr Virus (EBV) infection in solid organ transplant recipients." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283206.

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8

Garrett, Giorgia L., Paul D. Blanc, John Boscardin, Amanda Abramson Lloyd, Rehana L. Ahmed, Tiffany Anthony, Kristin Bibee, et al. "Incidence of and Risk Factors for Skin Cancer in Organ Transplant Recipients in the United States." AMER MEDICAL ASSOC, 2017. http://hdl.handle.net/10150/623191.

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Анотація:
IMPORTANCE Skin cancer is the most common malignancy occurring after organ transplantation. Although previous research has reported an increased risk of skin cancer in solid organ transplant recipients (OTRs), no study has estimated the posttransplant population-based incidence in the United States. OBJECTIVE To determine the incidence and evaluate the risk factors for posttransplant skin cancer, including squamous cell carcinoma (SCC), melanoma (MM), and Merkel cell carcinoma (MCC) in a cohort of US OTRs receiving a primary organ transplant in 2003 or 2008. DESIGN, SETTING, AND PARTICIPANTS This multicenter retrospective cohort study examined 10 649 adult recipients of a primary transplant performed at 26 centers across the United States in the Transplant Skin Cancer Network during 1 of 2 calendar years (either 2003 or 2008) identified through the Organ Procurement and Transplantation Network (OPTN) database. Recipients of all organs except intestine were included, and the follow-up periods were 5 and 10 years. MAIN OUTCOMES AND MEASURES Incident skin cancerwas determined through detailed medical record review. Data on predictors were obtained from the OPTN database. The incidence rates for posttransplant skin cancer overall and for SCC, MM, and MCC were calculated per 100 000 person-years. Potential risk factors for posttransplant skin cancer were tested using multivariate Cox regression analysis to yield adjusted hazard ratios (HR). RESULTS Overall, 10 649 organ transplant recipients (mean [SD] age, 51 [12] years; 3873 women [36%] and 6776 men [64%]) contributed 59 923 years of follow-up. The incidence rates for posttransplant skin cancer was 1437 per 100 000 person-years. Specific subtype rates for SCC, MM, and MCC were 812, 75, and 2 per 100 000 person-years, respectively. Statistically significant risk factors for posttransplant skin cancer included pretransplant skin cancer (HR, 4.69; 95% CI, 3.26-6.73), male sex (HR, 1.56; 95% CI, 1.34-1.81), white race (HR, 9.04; 95% CI, 6.20-13.18), age at transplant 50 years or older (HR, 2.77; 95% CI, 2.20-3.48), and being transplanted in 2008 vs 2003 (HR, 1.53; 95% CI, 1.22-1.94). CONCLUSIONS AND RELEVANCE Posttransplant skin cancer is common, with elevated risk imparted by increased age, white race, male sex, and thoracic organ transplantation. A temporal cohort effect was present. Understanding the risk factors and trends in posttransplant skin cancer is fundamental to targeted screening and prevention in this population.
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9

Tang, James. "Patient-centred digital technology to improve self-management and health outcomes in solid organ transplant recipients." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27380.

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Анотація:
Transplantation requires complex self-management regimens and life-long follow-up care to maintain graft survival and well-being. “eHealth”, defined as the use of the Internet and related digital technology to provide health services, can be utilised to promote self-management, facilitate patient-clinician communication, and improve clinical outcomes in chronic disease. However, there is insufficient evidence to support the routine adaption of eHealth use in kidney transplant recipients. This program of work will address uncertainties in the literature surrounding the effectiveness of eHealth in transplant care. Chapter 2 of this thesis provides a systematic review and meta-analysis of the benefits and harms of eHealth in post-transplant care. Medication taking remains the cornerstone of graft preservation and is a critical part of the self-management regime in transplant care. Chapter 3 of this thesis provides a systematic qualitative review of transplant recipients’ medication-taking perspectives. Chapter 4 addresses the uncertainties of transplant recipients’ perspectives on digital health technology. Therefore, we conducted semi-structured interviews among kidney transplant recipients to understand the perspectives and experiences of eHealth. Understanding the acceptance patterns and preferences for eHealth use in kidney transplant recipients will facilitate digital technology in transplant care. Chapters 5 and 6 of this thesis investigate the determinants and preferences of eHealth uptake in kidney transplant care. This thesis contains published or submitted studies that collectively assess the value of eHealth in transplantation, better understand medication-taking as part of self-management, describe recipients beliefs and experience for eHealth, and understand the determinants and preferences associated with eHealth uptake.
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10

Ye, X., J. N. Van, F. M. Munoz, P. A. Revell, Claudia A. Korinetz, R. A. Krance, R. L. Atmar, M. K. Estes, and H. L. Koo. "Noroviruses as a Cause of Diarrhea in Immunocompromised Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1490.

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Case reports describe significant norovirus gastroenteritis morbidity in immunocompromised patients. We evaluated norovirus pathogenesis in prospectively enrolled solid organ (SOT) and hematopoietic stem cell transplant (HSCT) patients with diarrhea who presented to Texas Children's Hospital and submitted stool for enteric testing. Noroviruses were detected by real-time reverse transcription polymerase chain reaction. Clinical outcomes of norovirus diarrhea and non-norovirus diarrhea patients, matched by transplanted organ type, were compared. Norovirus infection was identified in 25 (22%) of 116 patients, more frequently than other enteropathogens. Fifty percent of norovirus patients experienced diarrhea lasting ≥14 days, with median duration of 12.5 days (range 1–324 days); 29% developed diarrhea recurrence. Fifty-five percent of norovirus patients were hospitalized for diarrhea, with 27% requiring intensive care unit (ICU) admission. One HSCT recipient developed pneumatosis intestinalis. Three HSCT patients expired ≤6 months of norovirus diarrhea onset. Compared to non-norovirus diarrhea patients, norovirus patients experienced significantly more frequent ICU admission (27% vs. 0%, p = 0.02), greater serum creatinine rise (median 0.3 vs. 0.2 mg/dL, p = 0.01), and more weight loss (median 1.6 vs. 0.6 kg, p < 0.01). Noroviruses are an important cause of diarrhea in pediatric transplant patients and are associated with significant clinical complications.
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Книги з теми "Organ Transplant Recipient"

1

Register, Canadian Organ Replacement. Instruction manual, transplant recipient and organ donor information. Ottawa: Canadian Institute for Health Information, 2004.

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Wong, Christopher J., ed. Primary Care of the Solid Organ Transplant Recipient. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50629-2.

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3

Schmähl, Dietrich, and Israel Penn, eds. Cancer in Organ Transplant Recipients. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75991-8.

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Dietrich, Schmähl, Penn Israel, and Deutsches Krebsforschungszentrum Heidelberg, eds. Cancer in organ transplant recipients. Berlin: Springer-Verlag, 1991.

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5

Wijdicks, Eelco F. M., 1954-, ed. Neurologic complications in organ transplant recipients. Boston: Butterworth-Heinemann, 1999.

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6

Manuel, Oriol, and Michael G. Ison, eds. Infectious Diseases in Solid-Organ Transplant Recipients. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-15394-6.

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7

Nina, Singh, and Aguado José M, eds. Infectious complications in transplant recipients. Boston, Mass: Kluwer, 2001.

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8

Vitin, Alexander, ed. Perioperative Care for Organ Transplant Recipient. IntechOpen, 2019. http://dx.doi.org/10.5772/intechopen.77696.

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Vitin, Alexander. Perioperative Care for Organ Transplant Recipient. IntechOpen, 2019.

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Wong, Christopher. Primary Care of the Solid Organ Transplant Recipient. Springer, 2020.

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Частини книг з теми "Organ Transplant Recipient"

1

Rubin, Robert H. "Infection in the Organ Transplant Recipient." In Clinical Approach to Infection in the Compromised Host, 573–679. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/0-306-47527-8_17.

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2

Rubin, Robert H. "Infection in the Organ Transplant Recipient." In Clinical Approach to Infection in the Compromised Host, 629–705. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2490-8_24.

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3

Golden, Lessie Eric. "Considerations on the Relationship Between Living Organ Donor and Recipient." In Transplant Psychiatry, 297–300. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-15052-4_39.

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4

Ince, Dilek. "Altered Mental Status in the Solid Organ Transplant Recipient." In Emerging Transplant Infections, 1–12. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-01751-4_66-1.

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Ince, Dilek. "Altered Mental Status in the Solid Organ Transplant Recipient." In Emerging Transplant Infections, 1661–71. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-25869-6_66.

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6

Peris, Adriano, Jessica Bronzoni, Sonia Meli, Juri Ducci, Erjon Rreka, Davide Ghinolfi, Emanuele Balzano, Fabio Melandro, and Paolo De Simone. "Organ Donor Risk Stratification in Italy." In Textbook of Patient Safety and Clinical Risk Management, 319–23. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59403-9_23.

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AbstractThe permanent gap between organ demand and supply has prompted use of organs from extended criteria donors (ECD). These carry a higher risk of disease transmission, with regard to infections and malignancies. We present herein the donor risk stratification algorithm implemented in Italy since 2004 for identification management of donor-to-recipient risk of disease transmission. The principles underlying this algorithm are: (1) the risk of disease transmission must be assessed against the potential benefit for the transplant recipient (i.e., no donor can be excluded from evaluation and their organs might benefit potential candidates); (2) patients awaiting organ transplantation must be informed that the risk of disease transmission is small but finite (standard risk); and (3) risk evaluation is an ongoing process based on information collected longitudinally after transplantation. Regional and national transplant authorities are committed to regular updating of guidelines based on clinical data derived from clinicians and on evaluation of posttransplant graft and patient survival rates.
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7

Paine, Cary H., and Iris C. De Castro. "Primary Care of the Adult Kidney Transplant and Kidney-Pancreas Transplant Recipient." In Primary Care of the Solid Organ Transplant Recipient, 49–76. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50629-2_4.

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8

Parekh, Krishna N., Jerome C. Crowley, and Linda L. Liu. "Postoperative Care of the Liver Transplant Recipient." In Anesthesia and Perioperative Care for Organ Transplantation, 365–84. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6377-5_29.

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9

Issa, Naim, Scott A. Reule, and Aleksandra Kukla. "Metabolic and Endocrine Management of the Organ Transplant Recipient." In Textbook of Organ Transplantation, 1213–32. Oxford, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118873434.ch100.

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10

Berger, Gabrielle N., and Genevieve L. Pagalilauan. "Infections in the Adult Solid Organ Transplant Recipient." In Primary Care of the Solid Organ Transplant Recipient, 153–96. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50629-2_8.

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Тези доповідей конференцій з теми "Organ Transplant Recipient"

1

Purwaningsih, Sri Nurdiana. "Organ Transplant Agreement Between Donor and Recipient by Notary." In International Conference on Law, Economics and Health (ICLEH 2020). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/aebmr.k.200513.119.

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2

Vo, Hong-Phuong, and Umakanth Khatwa. "Pulmonary Function Changes In An Allograft Transmitted Histoplasma Capsulatum In A Pediatric Solid Organ Transplant Recipient." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3393.

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3

Nada, K. M. S. A., E. Polychronopoulo, G. Sharma, and A. G. Duarte. "Outcomes of SARS-CoV-2 Infection in Solid Organ Transplant Recipients." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4953.

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4

Galia, Kariv,. "A Model for Diagnosis of Pulmonary Infections in Solid-Organ Transplant Recipients." In Modeling and Control in Biomedical Systems, edited by Rees, Stephen, chair Andreassen, Steen and Andreassen, Steen. Elsevier, 2009. http://dx.doi.org/10.3182/20090812-3-dk-2006.00060.

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5

Garcia Ortega, Alberto, Raquel López Reyes, Gabriel Anguera De Francisco, Grace Oscullo Yépez, Remedios Otero Candelera, Manuel López-Meseguer, Andrés Quezada, Luis Jara-Palomares, and Manuel Monreal. "Venous thromboembolism in solid-organ transplant recipients: findings from the RIETE registry." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3571.

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6

Nada, K. M. S. A., E. Polychronopoulou, G. Sharma, and A. G. Duarte. "Comparison of Outcomes Among Solid Organ Transplant Recipients with SARS-CoV-2 Infection." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4942.

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7

Mahale, Parag, Meredith S. Shiels, and Eric A. Engels. "Abstract 273: Risk of primary central nervous system lymphomas in solid organ transplant recipients." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-273.

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8

Gibson, Todd M., Eric A. Engels, Christina A. Clarke, Ruth M. Pfeiffer, Charles F. Lynch, Ellen T. Chang, Erin Hall, Dennis D. Weisenburger, and Lindsay M. Morton. "Abstract 1025: Risk of diffuse large B-cell lymphoma in solid organ transplant recipients." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1025.

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9

Chiu, Wei-Che, Michalis Xenos, Yared Alemu, Gaurav Girdhar, Bryan Lynch, Jolyon Jesty, Marvin Slepian, Shmuel Einav, and Danny Bluestein. "Thrombogenicity Comparison of Axial Ventricular Assist Devices by DTE Methodology: MicroMed HeartAssist 5 and Thoratec Heartmate II." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80190.

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Mechanical circulatory devices, such as ventricular assist devices (VADs), have become the life-saving alternative for the patients who suffered from severe heart failure (1). These devices were utilized as the bridge-transplant devices; however, due to the fast growing population of cardiovascular diseases and the eligible organ donations are very limited, these devices have been considered for the application of life-long implantation. The continuous-flow VADs offer better hemodynamic performance than the first generations pulsatile flow VADs, its compact design offers surgical advantage; however, due to the non-physiological blood flow past constricted geometrics where platelets are exposed to elevated wall shear stress (2), VADs are burdened with high incidence of thromboembolic events, mandating anticoagulation therapies for its recipients (3).
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10

Santamäki, A., H. Kortejärvi, and L. Schepel. "INT-002 Standardisation of medication counselling material for paediatric solid organ transplant recipients and their families." In Abstract Book, 23rd EAHP Congress, 21st–23rd March 2018, Gothenburg, Sweden. British Medical Journal Publishing Group, 2018. http://dx.doi.org/10.1136/ejhpharm-2018-eahpconf.527.

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Звіти організацій з теми "Organ Transplant Recipient"

1

Wang, Li Fang, Yan Ting Cao, Tegeleqi Bu, Lin Fu, Jun Li Liu, and Jing Zhao. Do We Receive Cytomegalovirus Vaccination Before Solid Organ Transplant: a Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0143.

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Review question / Objective: We compared cytomegalovirus (CMV) vaccination for solid organ transplantation recipients ( SOTs) with placebo treatment, to investigate the efficacy and safety for the prevention of CMV infection in SOTs. Condition being studied: Patients after solid organ transplantation subsequently become immunosuppressed, and cytomegalovirus (CMV) is the most common opportunistic pathogen to this population. The prevalence of CMV infection can reach 50% in the general population, and further up to 64-72% in solid organ transplant recipients (SOTs). CMV seropositive donors (CMV D+) puts even more pressure of CMV infection for SOTs. Post-transplant CMV infection can lead to neutropenia, lymphopenia, thrombocytopenia, tissue/end-organ invasive CMV disease (gastroenteritis, pneumonia, hepatitis, encephalitis), other infectious diseases, graft dysfunction, and multiple organ failure. CMV can disturb immune cell function, thus is one of the major risk factors that increase mortality within 6 months after transplantation. However, practical, effective method to prevent postoperative CMV infection for SOTs remains unresolved. Vaccination of CMV is only at clinical trials stage. To date, there is a lack of guidelines or consensus for preventing CMV disease for SOTs. Given the increasing clinical trials of CMV vaccination, it is important to clarify the evidence-based benefits and risks of CMV vaccination for SOTs, and to provide the best CMV disease prevention measurements.
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Foulsham, Richard. Squamous cell carcinoma Prevention in Organ transplant recipients using Topical treatments (SPOT): a feasibility study. National Institute for Health and Care Research (NIHR), August 2022. http://dx.doi.org/10.3310/nihropenres.1115197.1.

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