Готові списки джерел за темами / OMPs

Добірка наукової літератури з теми "OMPs"

Автор: Grafiati
Опубліковано: 23 вересня 2022
Оновлено: 28 січня 2023

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Статті в журналах з теми "OMPs"

1

Puig, Marta, Carme Fusté, and Miquel Viñas. "Outer membrane proteins from Serratia marcescens." Canadian Journal of Microbiology 39, no. 1 (January 1, 1993): 108–11. http://dx.doi.org/10.1139/m93-015.

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Анотація:
The outer membrane proteins (OMPs) of several strains of Serratia marcescens have been studied by sodium dodecyl sulphate – urea – polyacrylamide gel electrophoresis. Four major OMPs, named Omp1, Omp2, Omp3, and OmpA (42, 40, 39, and 37 kDa, respectively), have been visualized. The relative proportions of Omp2 and Omp3 depend on cultural conditions (temperature of incubation, osmolarity, and nutrient availability).Key words: Serratia marcescens, outer membrane proteins, porin.
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2

Noh, Susan M., Kelly A. Brayton, Donald P. Knowles, Joseph T. Agnes, Michael J. Dark, Wendy C. Brown, Timothy V. Baszler, and Guy H. Palmer. "Differential Expression and Sequence Conservation of the Anaplasma marginale msp2 Gene Superfamily Outer Membrane Proteins." Infection and Immunity 74, no. 6 (June 2006): 3471–79. http://dx.doi.org/10.1128/iai.01843-05.

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ABSTRACT Bacterial pathogens in the genera Anaplasma and Ehrlichia encode a protein superfamily, pfam01617, which includes the predominant outer membrane proteins (OMPs) of each species, major surface protein 2 (MSP2) and MSP3 of Anaplasma marginale and Anaplasma ovis, Anaplasma phagocytophilum MSP2 (p44), Ehrlichia chaffeensis p28-OMP, Ehrlichia canis p30, and Ehrlichia ruminantium MAP1, and has been shown to be involved in both antigenic variation within the mammalian host and differential expression between the mammalian and arthropod hosts. Recently, complete sequencing of the A. marginale genome has identified an expanded set of genes, designated omp1-14, encoding new members of this superfamily. Transcriptional analysis indicated that, with the exception of the three smallest open reading frames, omp2, omp3, and omp6, these superfamily genes are transcribed in A. marginale-infected erythrocytes, tick midgut and salivary glands, and the IDE8 tick cell line. OMPs 1, 4, 7 to 9, and 11 were confirmed to be expressed as proteins by A. marginale within infected erythrocytes, with expression being either markedly lower (OMPs 1, 4, and 7 to 9) or absent (OMP11) in infected tick cells, which reflected regulation at the transcript level. Although the pfam01617 superfamily includes the antigenically variable MSP2 and MSP3 surface proteins, analysis of the omp1-14 sequences throughout a cycle of acute and persistent infection in the mammalian host and tick transmission reveals a high degree of conservation, an observation supported by sequence comparisons between the St. Maries strain and Florida strain genomes.
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3

Hellman, Judith, Paul M. Loiselle, Megan M. Tehan, Jennifer E. Allaire, Lenora A. Boyle, James T. Kurnick, David M. Andrews, Kwang Sik Kim, and H. Shaw Warren. "Outer Membrane Protein A, Peptidoglycan-Associated Lipoprotein, and Murein Lipoprotein Are Released by Escherichia coli Bacteria into Serum." Infection and Immunity 68, no. 5 (May 1, 2000): 2566–72. http://dx.doi.org/10.1128/iai.68.5.2566-2572.2000.

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ABSTRACT Complexes containing lipopolysaccharide (LPS) and three outer membrane proteins (OMPs) are released by gram-negative bacteria incubated in human serum and into the circulation in an experimental model of sepsis. The same OMPs are bound by immunoglobulin G (IgG) in the cross-protective antiserum raised to Escherichia coliJ5 (anti-J5 IgG). This study was performed to identify the three OMPs. The 35-kDa OMP was identified as outer membrane protein A (OmpA) by immunoblotting studies using OmpA-deficient bacteria and recombinant OmpA protein. The 18-kDa OMP was identified as peptidoglycan-associated lipoprotein (PAL) based on peptide sequences from the purified protein and immunoblotting studies using PAL-deficient bacteria. The 5- to 9-kDa OMP was identified as murein lipoprotein (MLP) based on immunoblotting studies using MLP-deficient bacteria. The studies identify the OMPs released into human serum and into the circulation in an experimental model of sepsis as OmpA, PAL, and MLP.
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4

Yang, Chen, Sijia Peng, Chunlai Chen, and Xin Sheng Zhao. "Molecular mechanism of networking among DegP, Skp and SurA in periplasm for biogenesis of outer membrane proteins." Biochemical Journal 477, no. 16 (August 19, 2020): 2949–65. http://dx.doi.org/10.1042/bcj20200483.

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Анотація:
The biogenesis of outer membrane proteins (OMPs) is an extremely challenging process. In the periplasm of Escherichia coli, a group of quality control factors work together to exercise the safe-guard and quality control of OMPs. DegP, Skp and SurA are the three most prominent ones. Although extensive investigations have been carried out, the molecular mechanism regarding the networking among these proteins remains mostly mysterious. Our group has previously studied the molecular interactions of OMPs with SurA and Skp, using single-molecule detection (SMD). In this work, again using SMD, we studied how OmpC, a representative of OMPs, interacts with DegP, Skp and SurA collectively. Several important discoveries were made. The self-oligomerization of DegP to form hexamer occurs over hundred micromolars. When OmpC is in a monomer state at a low concentration, the OmpC·DegP6 and OmpC·DegP24 complexes form when the DegP concentration is around sub-micromolars and a hundred micromolars, respectively. High OmpC concentration promotes the binding affinity of DegP to OmpC by ∼100 folds. Skp and SurA behave differently when they interact synergistically with DegP in the presence of substrate. DegP can degrade SurA-protected OmpC, but Skp-protected OmpC forms the ternary complex OmpC·(Skp3)n·DegP6 (n = 1,2) to resist the DegP-mediated degradation. Combined with previous results, we were able to depict a comprehensive picture regarding the molecular mechanism of the networking among DegP, Skp and SurA in the periplasm for the OMPs biogenesis under physiological and stressed conditions.
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5

Wu, Si, Xi Ge, Zhixin Lv, Zeyong Zhi, Zengyi Chang, and Xin Sheng Zhao. "Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism." Biochemical Journal 438, no. 3 (August 26, 2011): 505–11. http://dx.doi.org/10.1042/bj20110264.

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Анотація:
The OMPs (outer membrane proteins) of Gram-negative bacteria have to be translocated through the periplasmic space before reaching their final destination. The aqueous environment of the periplasmic space and high permeability of the outer membrane engender such a translocation process inevitably challenging. In Escherichia coli, although SurA, Skp and DegP have been identified to function in translocating OMPs across the periplasm, their precise roles and their relationship remain to be elucidated. In the present paper, by using fluorescence resonance energy transfer and single-molecule detection, we have studied the interaction between the OMP OmpC and these periplasmic quality control factors. The results of the present study reveal that the binding rate of OmpC to SurA or Skp is much faster than that to DegP, which may lead to sequential interaction between OMPs and different quality control factors. Such a kinetic partitioning mechanism for the chaperone–substrate interaction may be essential for the quality control of the biogenesis of OMPs
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6

Zhang, Shuang, Yu Cheng, Jing Ma, Yan Wang, Zengyi Chang, and Xinmiao Fu. "Degp degrades a wide range of substrate proteins in Escherichia coli under stress conditions." Biochemical Journal 476, no. 23 (December 3, 2019): 3549–64. http://dx.doi.org/10.1042/bcj20190446.

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DegP, a periplasmic dual-functional protease and chaperone in Gram-negative bacteria, is critical for bacterial stress resistance, but the precise underlying mechanisms are not fully understood. Here, we show that the protease function of DegP is critical for Escherichia coli cells to maintain membrane integrity, particularly under heat shock conditions (42°C). Site-directed photo-cross-linking, mass spectrometry and immunoblotting analyses reveal that both periplasmic proteins (e.g. OppA and MalE) and β-barrel outer membrane proteins (OMPs) are DegP-interacting proteins and that OppA is degraded by DegP in vitro and in vivo at 42°C. In addition, OmpA and BamA, chimeric β-barrel OMPs containing a soluble periplasmic domain, are bound to DegP in both unfolded and folded forms, whereas only the unfolded forms are degradable by DegP. The presence of folded OmpA as a substrate of DegP is attributed to its periplasmic domain, which is resistant to DegP degradation and even generally protects pure β-barrel OMPs from degradation in an intra-molecular way. Furthermore, a pair of residues (R262 and V328) in the PDZ domain-1 of DegP play important roles for binding unfolded and folded β-barrel OMPs, with R262 being critical. Our study, together with earlier reports, indicates that DegP plays a critical role in protein quality control in the bacterial periplasm by degrading both periplasmic proteins and β-barrel OMPs under stress conditions and likely also by participating in the folding of chimeric β-barrel OMPs. A working model is proposed to illustrate the finely tuned functions of DegP with respect to different substrate proteins.
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7

Rodrigues, Inês C., Sílvia C. Rodrigues, Filipe V. Duarte, Paula M. da Costa, and Paulo M. da Costa. "The Role of Outer Membrane Proteins in UPEC Antimicrobial Resistance: A Systematic Review." Membranes 12, no. 10 (October 10, 2022): 981. http://dx.doi.org/10.3390/membranes12100981.

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Uropathogenic Escherichia coli (UPEC) are one of the most common agents of urinary tract infection. In the last decade, several UPEC strains have acquired antibiotic resistance mechanisms and some have become resistant to all classes of antibiotics. UPEC outer membrane proteins (OMPs) seem to have a decisive role not only in the processes of invasion and colonization of the bladder mucosa, but also in mechanisms of drug resistance, by which bacteria avoid killing by antimicrobial molecules. This systematic review was performed according to the PRISMA guidelines, aiming to characterize UPEC OMPs and identify their potential role in antimicrobial resistance. The search was limited to studies in English published during the last decade. Twenty-nine studies were included for revision and, among the 76 proteins identified, seven were associated with antibiotic resistance. Indeed, OmpC was associated with β-lactams resistance and OmpF with β-lactams and fluoroquinolone resistance. In turn, TolC, OmpX, YddB, TosA and murein lipoprotein (Lpp) were associated with fluoroquinolones, enrofloxacin, novobiocin, β-lactams and globomycin resistances, respectively. The clinical implications of UPEC resistance to antimicrobial agents in both veterinary and human medicine must propel the implementation of new strategies of administration of antimicrobial agents, while also promoting the development of improved antimicrobials, protective vaccines and specific inhibitors of virulence and resistance factors.
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8

Mills, Scott D., Sharon R. Ruschkowski, Murry A. Stein, and B. Brett Finlay. "Trafficking of Porin-Deficient Salmonella typhimurium Mutants inside HeLa Cells: ompR andenvZ Mutants Are Defective for the Formation ofSalmonella-Induced Filaments." Infection and Immunity 66, no. 4 (April 1, 1998): 1806–11. http://dx.doi.org/10.1128/iai.66.4.1806-1811.1998.

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ABSTRACT Outer membrane porin genes of Salmonella typhimurium, including ompC, ompF, and tppB, are regulated by the products of ompB, a two-component regulatory locus encoding OmpR and EnvZ. S. typhimurium ompR mutants are attenuated in mice, but to date no one has studied the intracellular trafficking of S. typhimuriumporin-deficient mutants. In this study, isogenic transposon mutants ofS. typhimurium with insertions in ompR,envZ, ompF, ompC, ompD,osmZ, and tppB were compared with wild-type SL1344 for trafficking in the human epithelial cell line HeLa. We found that ompR and envZ mutants were reduced or completely inhibited for the formation ofSalmonella-induced filaments (Sifs). This result was confirmed with an ompB deletion mutant. Sifs are tubular structures containing lysosomal glycoprotein which are induced specifically by intracellular Salmonella. Genetic analysis showed that the ompR mutation could be complemented intrans by cloned ompR to restore its ability to induce Sifs. In contrast, mutations in the knownompR-regulated genes ompF, ompC, and tppB (as well as the ompR-independent porin gene, ompD) had no effect on Sif formation relative to that of wild-type SL1344, thus indicating that OmpR does not exert its role on these genes to induce Sif formation. The omp mutants studied were able to invade and replicate in HeLa cells at levels comparable to those in wild-type SL1344. We conclude that OmpR and EnvZ appear to regulate Sif formation triggered by intracellular S. typhimurium.
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9

Engström, Patrik, Thomas P. Burke, Cuong J. Tran, Anthony T. Iavarone, and Matthew D. Welch. "Lysine methylation shields an intracellular pathogen from ubiquitylation and autophagy." Science Advances 7, no. 26 (June 2021): eabg2517. http://dx.doi.org/10.1126/sciadv.abg2517.

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Many intracellular pathogens avoid detection by their host cells. However, it remains unknown how they avoid being tagged by ubiquitin, an initial step leading to antimicrobial autophagy. Here, we show that the intracellular bacterial pathogen Rickettsia parkeri uses two protein-lysine methyltransferases (PKMTs) to modify outer membrane proteins (OMPs) and prevent their ubiquitylation. Mutants deficient in the PKMTs were avirulent in mice and failed to grow in macrophages because of ubiquitylation and autophagic targeting. Lysine methylation protected the abundant surface protein OmpB from ubiquitin-dependent depletion from the bacterial surface. Analysis of the lysine-methylome revealed that PKMTs modify a subset of OMPs, including OmpB, by methylation at the same sites that are modified by host ubiquitin. These findings show that lysine methylation is an essential determinant of rickettsial pathogenesis that shields bacterial proteins from ubiquitylation to evade autophagic targeting.
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10

Zhou, Yan, Fu Wei Huang, Fa Rong Huang, and Lei Du. "Preparation and Properties of Silicon-Containing Arylacetylene Resins with Octa(maleimidophenyl)silsesquioxane." Advanced Materials Research 557-559 (July 2012): 1152–56. http://dx.doi.org/10.4028/www.scientific.net/amr.557-559.1152.

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Modified silicon-containing arylacetylene resins (DMSEPE-OMPS) were prepared from poly(dimethylsilyleneethynylenephenyleneethynylene) (DMSEPE) and Octa(maleimidophenyl)- silsesquioxane (OMPS). The curing reaction of DMSEPE-OMPS resin was studied by FT-IR and DSC techniques. Thermal stability and dielectric properties of cured DMSEPE-OMPS resins were determined. FT-IR and DSC analyses indicate that thermal polymerization of DMSEPE-OMPS resin occurs in the curing process. Thermal stabilities of cured DMSEPE-OMPS resins under N2 and air atmosphere decrease gradually with the increment of OMPS components. The incorporation of OMPS can obviously reduce dielectric constant of DMSEPE-OMPS resins.
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Більше джерел

Дисертації з теми "OMPs"

1

Wang, Yi. "Geos-chem adjoint inversion of SO2 and NOx emissions with multi-sensor (OMPS, OMI, and VIIRS) data over China." Diss., University of Iowa, 2019. https://ir.uiowa.edu/etd/7042.

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Accurate and timely SO2 and NOx emission inventories are required to simulate and forecast SO2 and NO2 concentrations in the atmosphere. However, bottom-up emission inventories have a time lag of at least one year, as it takes time to collect necessary activity rates and emission factors. This thesis focuses on using satellite data from Ozone Monitoring Instrument (OMI), Ozone Mapper and Profile Suite (OMPS), and Visible Infrared Imaging Radiometer Suite (VIIRS) to optimize SO2 and NOx emissions through the GEOS-Chem adjoint model. The optimized emission inventories are further applied to improve air quality simulation and forecasts. We firstly integrate OMI SO2 satellite measurements and GEOS-Chem adjoint model simulations to constrain monthly anthropogenic SO2 emissions. The effectiveness of this approach is demonstrated for 14 months over China; resultant posterior emissions not only capture a 20% SO2 emission reduction in Beijing during the 2008 Olympic Games but also improve agreement between modeled and in situ surface measurements. Further analysis reveals that posterior emissions estimates, compared to the prior, lead to significant improvements in forecasting monthly surface and columnar SO2. SO2 and NO2 observations from the newer sensor OMPS are used to optimize SO2 and NOx emissions over China for October 2013 through GEOS-Chem adjoint model. OMPS SO2 and NO2 observations are assimilated separately to optimize corresponding emissions, respectively, and posterior emissions, compared to the prior, yield improvements in simulating columnar SO2 and NO2, which are validated with both OMI and OMPS observations. The posterior emissions from assimilating OMPS SO2 and NO2 simultaneously are within -3% to 15% of separate assimilations for SO2 emissions and ±1% for NOx, and the joint assimilation saves about 50% computational time. Changes of NH3 emissions modify NO2 lifetime, hence affecting posterior NOx emissions in separate assimilations, and having impacts on both posterior SO2 and NOx emissions in joint assimilation. All these assimilation experiments are conducted at coarse (2°×2.5°) spatial resolution to save computational time, but coarse-resolution simulations underestimate hot spots of surface SO2 and NO2. Thus, the posterior coarse-resolution emissions are further efficiently downscaled to fine resolution (0.25°×0.3125°) according to spatial distributions of prior MIX emissions or VIIRS nighttime lights. Posterior fine-resolution simulation and forecasts, validating with in situ surface SO2 and NO2 measurements, improve on the prior ones.
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2

Yang, Yiying. "Mécanismes de biogenèse et de maintien de la membrane externe des bactéries à Gram négatif." Thesis, Toulouse 3, 2021. http://www.theses.fr/2021TOU30279.

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Анотація:
Les bactéries à Gram négatif comprennent un certain nombre d'agents pathogènes animaux redoutables qui sont particulièrement résistants aux thérapies antibiotiques grâce à la fonction protectrice de leur enveloppe bactérienne. L'enveloppe des bactéries à Gram négatif est composée d'une membrane interne (MI) et d'une membrane externe (ME), séparées par un espace, le périplasme, contenant le peptidoglycane (PG). Le feuillet externe de la bicouche de la ME contient des lipopolysaccharides (LPS) qui forment une barrière imperméable à certaines molécules toxiques, tels que les détergents ou des petites molécules hydrophobes. Les nutriments sont transportés par les protéines (OMP) de la ME. D'autres OMP remplissent des fonctions de biogenèse de l'enveloppe, notamment l'assemblage des OMP et des LPS. Les OMP sont assemblées dans la ME par le complexe d'assemblage en tonneau bêta (BAM), un hétéro-pentamère contenant l'OMP essentielle BamA et quatre lipoprotéines BamBCDE. L'assemblage du LPS nécessite une autre OMP essentielle, LptD, qui s'associe de manière stable avec la lipoprotéine LptE. Un assemblage défectueux des OMP provoque un stress de l'enveloppe et rend les bactéries Gram-négatives sensibles aux antibiotiques et aux détergents. Le complexe BAM représente donc une cible prometteuse pour le développement de nouveaux antibiotiques. La fonction moléculaire du complexe BAM dans la biogénèse des ME est mal comprise. En utilisant une stratégie de spectrométrie de masse quantitative, le laboratoire d'accueil a récemment identifié deux nouveaux interacteurs putatifs du complexe BAM, les lipoprotéines DolP (anciennement YraP) et YifL, toutes deux de fonctions inconnues. L'objectif de ce travail de thèse était de caractériser les rôles respectifs de DolP et YifL au sein du complexe BAM. DolP est une lipoprotéine de la ME de 20 kDa. L’accumulation d’OMP mal repliées dans le périplasme induit un stress de l’enveloppe qui, à son tour, stimule la production à la fois de BamA et de DolP. Cependant, le rôle de cette dernière dans la biogenèse des OMP n’est pas connu. Dans cette étude, en utilisant un crible génétique, nous avons montré que DolP est critique pour la croissance des cellules qui subissent un stress d'enveloppe. Nous avons montré que l’accumulation de BamA dans la ME est toxique pour les cellules mais que DolP est capable de contrecarrer cette toxicité en favorisant le bon repliement de BamA (Ranavaco-first; Yangco-first; Orenday-Tapiaco-first, et al., 2021). En parallèle, la caractérisation de l'interaction BAM-YifL a permis de montrer que YifL interagit avec BamA et BamD. De manière intéressante, nous avons découvert que YifL interagit également avec la machinerie de sécrétion des LPS, LptDE, qui est assemblée par le complexe BAM dans la ME. Ce processus nécessite également la machinerie de repliement oxydatif DsbA pour oxyder les 4 résidus de cystéine dans LptD de façon séquentielle. Une analyse génétique a montré que la délétion de yifL exacerbe la sensibilité des cellules bamB ou dsbA au SDS, un détergent normalement exclu par la couche de LPS. Nous avons constaté qu'en l'absence de YifL, LptD se fixe transitoirement au complexe BAM sous une forme intermédiaire partiellement oxydée. L'oxydation efficace de LptD pour former une protéine mature et fonctionnelle nécessite YifL. Nos résultats révèlent pour la première fois que YifL est critique pour la biogenèse efficace du complexe LptDE
Gram-negative bacteria include a number of dreadful animal pathogens that are particularly resistant to antibiotic therapies thanks to the sheltering function of their bacterial envelope. The envelope is composed of an inner and an outer membrane (IM and OM), and the separating periplasm containing the peptidoglycan (PG). The outer leaflet of the OM bilayer largely consists of lipopolysaccharide (LPS) that forms a permeability barrier against toxic molecules, including detergents and small hydrophobic molecules. Nutrients are transported via OM-spanning proteins (OMPs). Other OMPs perform envelope biogenesis functions, including the assembly of OMPs and LPS. OMPs are assembled into the OM by the beta-barrel assembly machinery (BAM), a heteropentamer containing the essential OMP BamA and four lipoproteins BamBCDE. The assembly of LPS requires another essential OMP, LptD, which stably associates with the lipoprotein LptE. Defective assembly of OMPs causes envelope stress and renders Gram-negative bacteria sensitive to antibiotics and detergents. Hence, the BAM complex represents a promising target for the development of new therapies. The mechanistic details of how the BAM complex functions ensuring efficient OM biogenesis are only marginally understood. By using a quantitative mass-spectrometry strategy the hosting lab has recently identified two novel putative interactors of the BAM complex of Escherichia coli, the lipoproteins DolP (formerly YraP) and YifL, both of unknown functions. The aim of this PhD thesis work was to characterize the roles of DolP and YifL at the BAM complex. DolP is a ~20 kDa OM lipoprotein that localizes in the periphery of E. coli cells and accumulates at the mid-cell specifically during a late step of cell division. DolP is upregulated during envelope stress caused by the accumulation of unfolded OMPs in the periplasm. Whether DolP plays any role in OMP biogenesis, however, was unknown. In this study, by using a genetic screen, we have shown that DolP is critical for the fitness of cells that undergo envelope stress. We have demonstrated that an increment of BamA in the OM, which is also upregulated during envelope stress, is potentially toxic for the cells. We provide evidence that DolP promotes proper folding and function of BamA thereby counteracting its toxicity. The mid-cell recruitment of DolP had been linked to regulation of septal peptidoglycan hydrolysis by an unknown mechanism. Our study reveals that during envelope stress DolP loses its association with the mid-cell, thus revealing a mechanistic link between impaired OMP biogenesis and a late step of cell division (Ranavaco-first; Yangco-first; Orenday-Tapiaco-first, et al., 2021). Next the BAM-YifL interaction was characterized. We showed that the ~7 kDa YifL interacts with BamA and BamD. Interestingly, we have found that YifL also interacts with the LPS secretory machinery LptDE, which is assembled by the BAM complex into the OM
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3

Pezeshki, Soroosh [Verfasser]. "Simulation of Transport through OmpF and OmpC Channels / Soroosh Pezeshki." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2010. http://d-nb.info/1034994654/34.

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4

Pathania, Monisha. "Characterisation of the major porins OmpU and OmpT of Vibrio cholerae." Thesis, University of Newcastle upon Tyne, 2018. http://hdl.handle.net/10443/4181.

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Анотація:
The asymmetric outer membrane (OM) of a Gram-negative bacterium has many proteins embedded as β-barrel structures in it called outer membrane proteins (OMPs). The majority of these OMPs (porins) form non-selective channels across the OM to allow passive uptake of substrates. The treatment for infections caused by such bacteria mostly involves the administration of drugs/antibiotics, for which these porins play a very crucial role by providing an efficient (although not yet fully understood) route through their channel. The goal of this study is to study small-molecule permeation through the major porins, OmpU and OmpT, of Vibrio cholerae (the causative agent of cholera) for potential use of these proteins as the target for designing antibiotics or vaccines. Towards this project, we have succeeded in solving the 3D X-ray crystal structures of OmpU and OmpT as well as the structures of the major porins from Klebsiella pneumoniae (OmpK36) and Enterobacter cloacae (OmpE36, OmpE35). The proteins (OmpU/T, OmpE35/E36 and OmpK36) show the typical arrangement of porins with three β-barrel monomers arranged into a trimer. Each monomer displays 16 antiparallel β-strands forming the hollow β-barrel formed by 8 long extracellular loops and 8 short periplasmic turns. The latching loop L2 stabilises the trimer while loop L3 departs from the β-barrel fold and constricts the pore half-way through the channel. An unusual feature is observed in the channels of OmpU and OmpT that distinguishes them from other typical porins. In OmpU, the first 10 residues of N-terminus insert into the barrel and constrict the pore. In contrast, the structure of OmpT reveals that the extracellular loop L8 folds inwards to constrict the lumen of the channel. Such constriction elements not only reduce the pore sizes of OmpU and OmpT but may also dramatically affect the internal electrostatics of these channels, which is very important for small-molecule permeation. In addition, we also performed single channel electrophysiology experiments with OmpU and OmpT which revealed interesting features with the addition of carbapenems.
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5

Moya, Torres Aniel. "The role of Serratia marcescens OmpF and OmpC porins in antibiotic resistance and virulence." Microbiology, 2014. http://hdl.handle.net/1993/30388.

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Serratia marcescens is a microorganism that constitutes one of the primary causes of nosocomial outbreaks in hospitals. One characteristic of S. marcescens clinical isolates is the high resistance to antimicrobials used in the clinic. Recent reports have attributed antibiotic resistance to altered porin expression. In this study, S. marcescens Db11 isogenic porin mutants were generated using the generalized transducing phage IF3 to move marked target-genes between isogenic strain backgrounds, prior to removal of the antibiotic resistance cassette by Flp-FRT strategy. Mutants for three classical porins were obtained and the effect of ompF and ompC deletion on antimicrobial resistance was evaluated by MIC. The use of this method avoided the incorporation of additional resistance markers and is an alternative strategy to create clean unmarked Serratia mutant strains. The lack of OmpF, but not OmpC, significantly increased MIC values to the β-lactam drugs such as ampicillin and cefoxitin as well as to nitrofurantoin. Genetic deletion of both ompF and ompC did not compromise the integrity of the bacterial cell envelope in optimal growth conditions, suggesting that other outer-membrane porins may function in a compensatory role to facilitate nutrient uptake and cell envelope integrity. S. marcescens is a pathogen of C. elegans and can be used to study host response to bacterial infections. The host model Caenorhabditis elegans was used in this study to investigate if porin deficits affected bacterial virulence. When porin mutants were evaluated in the C. elegans host model, the virulence of the single porin mutant strains increased in comparison to the wild-type. This study demonstrated that mutations of ompF and ompC did not attenuate S. marcescens virulence, but rather demonstrated a hypervirulent phenotype when they were assessed in C. elegans. The absence of OmpF and OmpC porins in S. marcescens appeared to increase the bacterial invasion of C. elegans nematode tissue. Further studies are required to fully investigate the hypervirulent phenotype of these mutant strains. This study reveals that decrease of outer membrane permeability due to porin mutation alters antimicrobial resistance and does not generate virulence attenuation in S. marcescens Db11.
May 2015
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Aguilar, Mónica Alejandra Pavez. "Caracterização molecular da resistência aos carbapenêmicos em enterobactérias isoladas em hospitais brasileiros." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-28092009-144325/.

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Introdução: Após o surgimento e disseminação das β-lactamases (BL) de amplo espectro em membros da família Enterobacteriaceae, os antibióticos carbapenêmicos (imipenem, meropenem, ertapenem) têm sido considerados a terapia de escolha pela estabilidade apresentada contra estas enzimas. Infelizmente, em 2005, o primeiro caso de infecção fatal por um isolado de Klebsiella pneumoniae resistente aos carbapenêmicos foi relatado em nosso país. A partir deste, novos casos de infecção, inclusive por outros gêneros da família Enterobacteriaceae como Enterobacter, Providencia e Escherichia, começaram a surgir. Como mecanismo de resistência aos carbapenêmicos, a expressão de enzimas carbapenemases tem sido mundialmente relatada, enquanto que, a impermeabilidade associada à produção de enzimas do tipo AmpC ou ESBL tem sido esporádica. Com relação à mobilização dos determinantes genéticos de resistência, elementos móveis como integrons e plasmídios têm sido associados. O presente trabalho teve como objetivo caracterizar os mecanismos de resistência aos carbapenêmicos, sua mobilização genética e disseminação clonal em amostras clínicas de enterobactérias isoladas em diversos hospitais brasileiros. Material e métodos: Foram estudadas 28 cepas recuperadas de oito centros hospitalares descritas como resistentes ao imipenem. A caracterização fenotípica foi realizada por: i) determinação da CIM na presença e ausência de inibidores de BL, ii) bioensaio para produção de BL e iii) SDS-PAGE para investigar a ausência de porinas. A confirmação genotípica da resistência mediada por β-lactamases foi realizada por PCR e seqüenciamento e a sua localização plasmidial foi estudada por transformação. Por último, a tipagem molecular foi realizada pela técnica de ERIC-PCR, sendo confirmada pela técnica de PFGE. Resultados: 25 cepas apresentaram resistência para carbapenêmicos (imipenem MIC 8-128 µg/mL), todas com perfil de multiresistência incluindo cefoxitina (CIM90 ≥32 µg/mL). Foram identificados três determinantes de resistência, entre eles, a produção de carbapenemases de tipo MBL (IMP-1) e a enzima KPC-2, recentemente descrita, sendo emergente no país. O mecanismo mais prevalente nas amostras estudadas foi a impermeabilidade de membrana associada à expressão de enzimas do tipo AmpC (CMY-2 plasmidial para E. coli e AmpC cromossômica no caso de Enterobacter aerogenes), as quais mostraram uma contribuição significativa para a resistência aos carbapenêmicos. Dos 28 isolados, 18 apresentaram a perda da porina de 36 kDa, responsável pela entrada de antimicrobianos na bactéria, como os carbapenêmicos. Tanto os genes blaKPC-2 e blaCMY-2 foram transferidos com êxito para E. coli DH10B, confirmando sua localização plasmidial. A co-produção de carbapenemase ou enzimas do tipo AmpC com ESBL do tipo CTX-M foi confirmada em 68% dos isolados. A tipagem molecular mostrou uma disseminação clonal para os isolados carregando determinantes IMP-1 e as enzimas do tipo AmpC cromossômica e plasmidial. Ao contrário, isolados expressando KPC não foram clonalmente relacionadas. Conclusão: A caracterização de resistência apresentada neste trabalho demonstrou uma mudança no perfil de resistência da família Enterobactériaceae devido à sua versatilidade para a aquisição de novos mecanismos de resistência, como sua adaptação aos ambientes hostis. A perda da porina foi o mecanismo mais freqüente nesta família e a co-produção de BL foi um evento associado. Finalmente, os dados obtidos na tipagem molecular denotaram uma disseminação majoritariamente clonal na cidade de São Paulo, com exceção das cepas produtoras de KPC-2, cuja presença tem sido relatada em outras cidades do país, sugerindo a participação de uma transferência horizontal.
Introduction: After emergence, and dissemination of extended spectrum β-lactamases (ESBL) in members of the Enterobacteriaceae family, carbapenem antibiotics (imipenem, meropenem, ertapenem) have been the therapy of choice, since they are stable to ESBL hydrolysis. Unfortunately, in 2005, the first fatal case of infection by carbapenem-resistant Klebsiella pneumoniae was related in our country. From this episode, new infection cases, including by other genders of Enterobacteriaceae such as Enterobacter, Providencia and Escherichia, began to appear. Regarding carbapenem resistance mechanisms, expression of carbapenem hydrolyzing enzymes has been worldwide reported, whereas interplay between impermeability and AmpC or ESBL production has been sporadic. Furthermore, integrons and plasmids have been associated with mobilization of genetic determinants. The aim of this study was to characterize the mechanisms of resistance to carbapenems, their genetic mobilization and clonal dissemination in enterobacterial isolates recovered from clinical samples in Brazilian hospitals. Material and methods: 28 imipenem-resistant isolates recovered from 8 hospital centres were studied. Phenotypic profiles were characterized by: i) MIC of carbapenems in the presence/absence of β-lactamase inhibitors; ii) bioassay for β-lactamase production; iii) SDS-PAGE to investigate absence of outer membrane porins (OMPs). Molecular characterization of β-lactamase-mediated resistance was made by PCR and DNA sequencing and their plasmid localization was evaluated by transformation. Finally, epidemiological typing was performed by ERIC-PCR, being confirmed by PFGE. Results: 25 isolates were confirmed as being resistant to imipenem (MIC 8-128 µg/mL), exhibiting a multidrug-resistant profile, including to cefoxitin (MIC90 ≥32 µg/mL). Two main mechanism of resistance were identified: i) hydrolysis of carbapenem by class B (IMP-1-like MBL) and class A (KPC-2) enzymes, (the latter being recently reported in our country), and ii) outer membrane impermeability associated to AmpC enzyme production (plasmid-mediated CMY-2 for E. coli and chromosomal AmpC for E. aerogenes), which was the most prevalent mechanism found. Eighteen of 28 isolates lacked 36kDa OMP, which is responsible for uptake of carbapenem antibiotics. The blaKPC-2 and blaCMY-2 genes were successful transferred to E. coli DH10B, confirming the plasmid location of both genes. Co-production of carbapenemases or AmpC and CTXM enzymes was confirmed in 68% of isolates, and molecular typing showed clonal dissemination of IMP-1-, plasmid AmpC- and chromosomal AmpC-producing isolates. Otherwise, KPC-2-producing isolates were not clonally related. Conclusion: The characterization of resistance mechanisms to carbapenems, in this study, reveals a change in the resistance patterns among Enterobacteriaceae family members in Brazilian hospitals, due to versatility of isolates to acquire new resistance determinants, which it has favoured the adaptation to hostile environments. Lack of 36 kDa OMP was the most frequent resistance mechanism, being associated to co-production of β-lactamases. Finally, molecular typing denote a clonal dissemination of imipenem-resistant isolates in Sao Paulo city, with exception of KPC-2-producing isolates, which have been described in other Brazilian cities, suggesting a horizontal gene transfer.
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Arosio, Carlo [Verfasser], John P. [Akademischer Betreuer] Burrows, John P. [Gutachter] Burrows, and Erkki [Gutachter] Kyrölä. "Retrieval of ozone profiles from OMPS-LP observations and merging with SCIAMACHY and SAGE II time series to study long-term changes / Carlo Arosio ; Gutachter: John P. Burrows, Erkki Kyrölä ; Betreuer: John P. Burrows." Bremen : Staats- und Universitätsbibliothek Bremen, 2019. http://d-nb.info/1192909860/34.

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Dumetz, Fabien. "Les antigènes de surface de Flavobacterium psychrophilum : approche protéomique et caractérisation de deux protéines (OmpA/P60 et OmpH/P18)." Bordeaux 2, 2006. http://www.theses.fr/2006BOR21363.

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Flavobacterium est une bactérie Gram négative pathogène de poissons. Par une approche protéomique, nous avons pu identifier certains composants de la membrane externe : des adhésines putatives, des protéines impliquées dans l'acquisition du fer ou dans les systèmes d'efflux, une HtrA homologue et plusieurs molécules de fonctions inconnues. L'analyse de la membrane externe a révélé plusieurs antigènes protéiques majoritaires dont OmpA/P60. La susceptibilité des deux protéines aux traitements in situ des cellules avec de la protéinase K et la mise en évidence d'effets bactériostatiques/bactéricides d'anticorps spécifiques indiquent sans ambiguité l'exposition en surface de ces deux molécules. Des essais de vaccination ont montré que ces deux protéines pouvaient induire un fort taux d'anticorps protecteurs. Ces résultats indiquent qu'OmpA/P60 et OmpH/P18 sont des candidats prometteurs pour le développement de futurs vaccins
Flavobacterium psychrophilum is a Gram negative bacteria responsible for fish infection. We used a proteomic approach to identify some outer membrane components such as putative adhesins, proteins involved in iron acquisition or in efflux systems, a HtrA homologue and some other molecules with unknown function. Several major antigens have been identified in the outer membrane including the two components OmpH/P18 and OmpA/P60. They are surface-exposed since they were completely digested by in situ proteinase K treatment and the two monospecific sera were bacteriostatic/bactericidal. Vaccination trials showed that both proteins can induce a high titter of specific antibodies which are protective. Collectively, these results indicate that these two proteins could be used in future vaccine development as promising candidate antigens
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Al-Akash, Ahmed M. "Increased expression of ompA, ompX, dedA, and gutS genes in Enterobacter sp. YSU in the presence of selenite." Youngstown State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1607517925584702.

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Subotic, Vladimir. "Evaluating techniques for parallelization tuning in MPI, OmpSs and MPI/OmpSs." Doctoral thesis, Universitat Politècnica de Catalunya, 2013. http://hdl.handle.net/10803/129573.

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Parallel programming is used to partition a computational problem among multiple processing units and to define how they interact (communicate and synchronize) in order to guarantee the correct result. The performance that is achieved when executing the parallel program on a parallel architecture is usually far from the optimal: computation unbalance and excessive interaction among processing units often cause lost cycles, reducing the efficiency of parallel computation. In this thesis we propose techniques oriented to better exploit parallelism in parallel applications, with emphasis in techniques that increase asynchronism. Theoretically, this type of parallelization tuning promises multiple benefits. First, it should mitigate communication and synchronization delays, thus increasing the overall performance. Furthermore, parallelization tuning should expose additional parallelism and therefore increase the scalability of execution. Finally, increased asynchronism would provide higher tolerance to slower networks and external noise. In the first part of this thesis, we study the potential for tuning MPI parallelism. More specifically, we explore automatic techniques to overlap communication and computation. We propose a speculative messaging technique that increases the overlap and requires no changes of the original MPI application. Our technique automatically identifies the application’s MPI activity and reinterprets that activity using optimally placed non-blocking MPI requests. We demonstrate that this overlapping technique increases the asynchronism of MPI messages, maximizing the overlap, and consequently leading to execution speedup and higher tolerance to bandwidth reduction. However, in the case of realistic scientific workloads, we show that the overlapping potential is significantly limited by the pattern by which each MPI process locally operates on MPI messages. In the second part of this thesis, we study the potential for tuning hybrid MPI/OmpSs parallelism. We try to gain a better understanding of the parallelism of hybrid MPI/OmpSs applications in order to evaluate how these applications would execute on future machines and to predict the execution bottlenecks that are likely to emerge. We explore how MPI/OmpSs applications could scale on the parallel machine with hundreds of cores per node. Furthermore, we investigate how this high parallelism within each node would reflect on the network constraints. We especially focus on identifying critical code sections in MPI/OmpSs. We devised a technique that quickly evaluates, for a given MPI/OmpSs application and the selected target machine, which code section should be optimized in order to gain the highest performance benefits. Also, this thesis studies techniques to quickly explore the potential OmpSs parallelism inherent in applications. We provide mechanisms to easily evaluate potential parallelism of any task decomposition. Furthermore, we describe an iterative trialand-error approach to search for a task decomposition that will expose sufficient parallelism for a given target machine. Finally, we explore potential of automating the iterative approach by capturing the programmers’ experience into an expert system that can autonomously lead the search process. Also, throughout the work on this thesis, we designed development tools that can be useful to other researchers in the field. The most advanced of these tools is Tareador – a tool to help porting MPI applications to MPI/OmpSs programming model. Tareador provides a simple interface to propose some decomposition of a code into OmpSs tasks. Tareador dynamically calculates data dependencies among the annotated tasks, and automatically estimates the potential OmpSs parallelization. Furthermore, Tareador gives additional hints on how to complete the process of porting the application to OmpSs. Tareador already proved itself useful, by being included in the academic classes on parallel programming at UPC.
La programación paralela consiste en dividir un problema de computación entre múltiples unidades de procesamiento y definir como interactúan (comunicación y sincronización) para garantizar un resultado correcto. El rendimiento de un programa paralelo normalmente está muy lejos de ser óptimo: el desequilibrio de la carga computacional y la excesiva interacción entre las unidades de procesamiento a menudo causa ciclos perdidos, reduciendo la eficiencia de la computación paralela. En esta tesis proponemos técnicas orientadas a explotar mejor el paralelismo en aplicaciones paralelas, poniendo énfasis en técnicas que incrementan el asincronismo. En teoría, estas técnicas prometen múltiples beneficios. Primero, tendrían que mitigar el retraso de la comunicación y la sincronización, y por lo tanto incrementar el rendimiento global. Además, la calibración de la paralelización tendría que exponer un paralelismo adicional, incrementando la escalabilidad de la ejecución. Finalmente, un incremente en el asincronismo proveería una tolerancia mayor a redes de comunicación lentas y ruido externo. En la primera parte de la tesis, estudiamos el potencial para la calibración del paralelismo a través de MPI. En concreto, exploramos técnicas automáticas para solapar la comunicación con la computación. Proponemos una técnica de mensajería especulativa que incrementa el solapamiento y no requiere cambios en la aplicación MPI original. Nuestra técnica identifica automáticamente la actividad MPI de la aplicación y la reinterpreta usando solicitudes MPI no bloqueantes situadas óptimamente. Demostramos que esta técnica maximiza el solapamiento y, en consecuencia, acelera la ejecución y permite una mayor tolerancia a las reducciones de ancho de banda. Aún así, en el caso de cargas de trabajo científico realistas, mostramos que el potencial de solapamiento está significativamente limitado por el patrón según el cual cada proceso MPI opera localmente en el paso de mensajes. En la segunda parte de esta tesis, exploramos el potencial para calibrar el paralelismo híbrido MPI/OmpSs. Intentamos obtener una comprensión mejor del paralelismo de aplicaciones híbridas MPI/OmpSs para evaluar de qué manera se ejecutarían en futuras máquinas. Exploramos como las aplicaciones MPI/OmpSs pueden escalar en una máquina paralela con centenares de núcleos por nodo. Además, investigamos cómo este paralelismo de cada nodo se reflejaría en las restricciones de la red de comunicación. En especia, nos concentramos en identificar secciones críticas de código en MPI/OmpSs. Hemos concebido una técnica que rápidamente evalúa, para una aplicación MPI/OmpSs dada y la máquina objetivo seleccionada, qué sección de código tendría que ser optimizada para obtener la mayor ganancia de rendimiento. También estudiamos técnicas para explorar rápidamente el paralelismo potencial de OmpSs inherente en las aplicaciones. Proporcionamos mecanismos para evaluar fácilmente el paralelismo potencial de cualquier descomposición en tareas. Además, describimos una aproximación iterativa para buscar una descomposición en tareas que mostrará el suficiente paralelismo en la máquina objetivo dada. Para finalizar, exploramos el potencial para automatizar la aproximación iterativa. En el trabajo expuesto en esta tesis hemos diseñado herramientas que pueden ser útiles para otros investigadores de este campo. La más avanzada es Tareador, una herramienta para ayudar a migrar aplicaciones al modelo de programación MPI/OmpSs. Tareador proporciona una interfaz simple para proponer una descomposición del código en tareas OmpSs. Tareador también calcula dinámicamente las dependencias de datos entre las tareas anotadas, y automáticamente estima el potencial de paralelización OmpSs. Por último, Tareador da indicaciones adicionales sobre como completar el proceso de migración a OmpSs. Tareador ya se ha mostrado útil al ser incluido en las clases de programación de la UPC.
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Книги з теми "OMPs"

1

Johansen, Hanna. Omps: Ein Dinosaurier zu viel. Zürich, Switzerland: Nagel & Kimche, 2003.

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Omas beste Rührkuchen. Augsburg: Weltbild, 2003.

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Ki omōs anthizei--. Athēna: Metaichmio, 2011.

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Ki omōs anthizei--. Athēna: Metaichmio, 2011.

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5

Hardig, Warren. Iron sharpens iron. Greenwood, Ind: OMS International, 1990.

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6

Zeltner, Eva. Hurra, wir sind Ompas! Oberhofen am Thunersee: Zytglogge, 2011.

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Rice, Mildred. The key goose and other lessons God taught me: A veteran missionary talks about her life during 38 years of service in China, Japan, and Taiwan. Greenwood, IN: OSM International, 1988.

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8

Erny, Edward. This one thing: The story of missionary leader Eugene Erny. Greenwood, IN: OMS International, 1991.

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9

Die besten Backrezepte aus Omas Zeiten. München: Compact Via, 2011.

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10

Ouellet, Pierre. L' omis ; suivi de, Plus un être ... Seyssel [France]: Champ Vallon, 1989.

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Частини книг з теми "OMPs"

1

Pettersson, A., E. Scheper, J. Tommassen, B. Kuipers, and J. T. Poolman. "Heterogeneity of Iron-Regulated Meningococcal 70 kDa and 98 kDa OMPs." In Neisseriae 1990, edited by Mark Achtman, Peter Kohl, Christian Marchal, Giovanna Morelli, Andrea Seiler, and Burghard Thiesen, 459–64. Berlin, Boston: De Gruyter, 1991. http://dx.doi.org/10.1515/9783110867787-081.

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2

Henderson, Deborah, Donna Tangen, Amyzar Alwi, Aliza Alwi, and Zaira Abu Hassan Shaari. "Collaborating to Work with and Against the Grain: Reshaping Outbound Mobility Programs (OMPs) in Pre-Service Teacher Education." In Reconstructing the Work of Teacher Educators, 115–34. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-2904-5_6.

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Barker, Thomas. "Motorcycle Clubs, Outlaw Motorcycle Clubs (OMCs), and Outlaw Motorcycle Gangs (OMGs)." In The Outlaw Biker Legacy of Violence, 7–24. New York, NY : Routledge, 2018.: Routledge, 2018. http://dx.doi.org/10.4324/9781351053655-3.

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Verma, Payal, and Deepak G. Krishnan. "Office-Based Anesthesia in Oral and Maxillofacial Surgery-The American Model and Training." In Oral and Maxillofacial Surgery for the Clinician, 79–93. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_6.

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AbstractAnxiety and pain control has been an inherent part of the oral and maxillofacial surgeon’s (OMS’s) armamentarium. In the United States, achieving competency in anesthesia is an integral part of oral and maxillofacial surgery (OMS) training curriculum. Further, OMS’s maintain the highest of standards in their practice of anesthesia outside the operating theaters. OMS-anesthesia-team model emphasizes patient safety. This requires rigorous training and meticulous standards of practice, not only by the surgeons but by the entire supporting team of office personnel. The American Association of Oral Maxillofacial Surgeons (AAOMS) endorses several critical steps in promoting the safety of this model in OMS offices. Periodic review of parameters of care, mandated training for office team and a peer review for office anesthesia evaluation of fellow OMSs are some of the critical components. AAOMS has a simulation based training to train teams in the provision of safe anesthesia in a low risk environment. Emphasis on appropriate patient selection, impeccable advanced anesthesia monitoring, and periodic strong didactic and skills based training supports the OMS-anesthesia-team in being a valid, safe practice model of anxiety and pain control in an outpatient setting.
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Bodelón, Gustavo, Elvira Marín, and Luis Ángel Fernández. "Analyzing the Role of Periplasmic Folding Factors in the Biogenesis of OMPs and Members of the Type V Secretion System." In Methods in Molecular Biology, 77–110. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2871-2_7.

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Protze, Joachim, Tim Cramer, Simon Convent, and Matthias S. Müller. "OMPT-Multiplex: Nesting of OMPT Tools." In Tools for High Performance Computing 2017, 73–83. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11987-4_5.

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Kolochavina, Maryna. "A Rapid Market Access Strategy for Orphan Medicinal Products (OMPs) with Highlights Regarding the Pricing and Reimbursement Process and Barriers to Patient Use." In Rare Disease Drug Development, 333–49. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78605-2_22.

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Misra, Sudip, Barun Kumar Saha, and Sujata Pal. "Heterogeneity in OMNs." In Computer Communications and Networks, 225–57. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29031-7_8.

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Misra, Sudip, Barun Kumar Saha, and Sujata Pal. "Enforcing Cooperation in OMNs." In Computer Communications and Networks, 191–221. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29031-7_7.

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Knox, George W., Gregg W. Etter, and Carter F. Smith. "Outlaw Motorcycle Gangs (OMGs)." In Gangs and Organized Crime, 117–38. New York, NY : Routledge, 2018.: Routledge, 2018. http://dx.doi.org/10.4324/9781315118604-4.

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Тези доповідей конференцій з теми "OMPs"

1

Bennett, Stephen C. "Radiometric calibration of the OMPS instruments for NPOESS." In SPIE Optical Engineering + Applications, edited by James J. Butler, Xiaoxiong Xiong, and Xingfa Gu. SPIE, 2009. http://dx.doi.org/10.1117/12.824766.

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Pan, C., F. Weng, T. Beck, D. Liang, E. Devaliere, W. Chen, and S. Ding. "Analysis of OMPS in-flight CCD dark current degradation." In IGARSS 2016 - 2016 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2016. http://dx.doi.org/10.1109/igarss.2016.7729506.

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Pan, C., F. Weng, X. Wu, M. Kowalewski, G. Jaross, and L. Flynn. "OMPS Nadir early on-orbit performance evaluation and calibration." In SPIE Asia-Pacific Remote Sensing, edited by Haruhisa Shimoda, Xiaoxiong Xiong, Changyong Cao, Xingfa Gu, Choen Kim, and A. S. Kiran Kumar. SPIE, 2012. http://dx.doi.org/10.1117/12.978707.

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4

Jaross, Glen, Grace Chen, Mark Kowitt, Jeremy Warner, Philippe Xu, Thomas Kelly, Michael Linda, and David Flittner. "Suomi NPP OMPS limb profiler initial sensor performance assessment." In SPIE Asia-Pacific Remote Sensing, edited by Haruhisa Shimoda, Xiaoxiong Xiong, Changyong Cao, Xingfa Gu, Choen Kim, and A. S. Kiran Kumar. SPIE, 2012. http://dx.doi.org/10.1117/12.979627.

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5

Rault, Didier F., and Robert Spurr. "The OMPS Limb Profiler instrument: two-dimensional retrieval algorithm." In Remote Sensing, edited by Richard H. Picard, Klaus Schäfer, Adolfo Comeron, and Michiel van Weele. SPIE, 2010. http://dx.doi.org/10.1117/12.864799.

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6

Pan, C., F. Weng, G. Jaross, X. Wu, M. Haken, L. Flynn, S. Janz, M. Caponi, M. Kowalewski, and R. Buss. "OMPS early orbit dark and bias evaluation and calibration." In IGARSS 2012 - 2012 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2012. http://dx.doi.org/10.1109/igarss.2012.6351358.

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7

Rault, Didier F., and Philippe Q. Xu. "Expected data quality from the upcoming OMPS/LP mission." In SPIE Remote Sensing, edited by Evgueni I. Kassianov, Adolfo Comeron, Richard H. Picard, and Klaus Schäfer. SPIE, 2011. http://dx.doi.org/10.1117/12.897848.

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8

Pan, Chunhui, Lihang Zhou, Changyong Cao, Lawrence Flynn, and Satya Kalluri. "Spectral Calibration of NOAA-20 OMPS Sensor Data Record." In IGARSS 2019 - 2019 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2019. http://dx.doi.org/10.1109/igarss.2019.8898250.

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9

Kowalewski, Matthew, Chunhui Pan, and Scott Janz. "Early orbit operations performance of the Suomi NPP OMPS instrument." In SPIE Optical Engineering + Applications, edited by James J. Butler, Xiaoxiong Xiong, and Xingfa Gu. SPIE, 2012. http://dx.doi.org/10.1117/12.929753.

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10

Butler, James J., Scott J. Janz, B. Carol Johnson, Robert D. Saunders, John W. Cooper, Matthew G. Kowalewski, and Robert A. Barnes. "Calibration of a radiance standard for the NPP/OMPS instrument." In SPIE Remote Sensing, edited by Roland Meynart, Steven P. Neeck, Haruhisa Shimoda, and Shahid Habib. SPIE, 2008. http://dx.doi.org/10.1117/12.800194.

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Звіти організацій з теми "OMPs"

1

Pritchard, Howard. Quadchart for ECP OMPI-X milestone STPR17-80. Office of Scientific and Technical Information (OSTI), December 2021. http://dx.doi.org/10.2172/1836974.

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2

Pritchard, Howard. Quadchart for ECP OMPI-X JIRA ISSUE STPR17-79. Office of Scientific and Technical Information (OSTI), December 2021. http://dx.doi.org/10.2172/1836954.

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3

Gross, T. F., and A. J. Williams. Bottom boundary layer measurements in OMP. Final report. Office of Scientific and Technical Information (OSTI), November 1998. http://dx.doi.org/10.2172/666245.

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4

Wexler, Hannah M. Bacteroides Fragilis OmpA: Utility as a Live Vaccine Vector for Biodefense Agents. Fort Belvoir, VA: Defense Technical Information Center, January 2008. http://dx.doi.org/10.21236/ada485749.

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5

Wexler, Hannah M. Bacteroides Fragilis OmpA: Utility as a Live Vaccine Vector for Biodefense Agents. Fort Belvoir, VA: Defense Technical Information Center, January 2009. http://dx.doi.org/10.21236/ada502764.

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6

Hayden, Linda B. Undergraduate Research Experience in Ocean/Marine Science (URE-OMS). Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada630026.

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7

Wexler, Hannah M. Bacteroides Fragilis OMP A: Utility as a Live Vaccine Vector for Biodefense Agents. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada448618.

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8

Hayden, Linda. Undergraduate Research Experience In Ocean/Marine Science (URE-OMS) with African Student Component. Fort Belvoir, VA: Defense Technical Information Center, January 2009. http://dx.doi.org/10.21236/ada531015.

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9

Hayden, Linda. Undergraduate Research Experience in Ocean/Marine Science (URE-OMS) with African Student Component. Fort Belvoir, VA: Defense Technical Information Center, January 2011. http://dx.doi.org/10.21236/ada540760.

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10

Hayden, Linda. Undergraduate Research Experience in Ocean/Marine Science (URE-OMS) with African Student Component. Fort Belvoir, VA: Defense Technical Information Center, January 2008. http://dx.doi.org/10.21236/ada514863.

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