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Статті в журналах з теми "Novel Molecules"
Yu, Chang Feng. "A Novel High Precision Analytic Potential Function for Diatomic Molecules." Key Engineering Materials 645-646 (May 2015): 313–18. http://dx.doi.org/10.4028/www.scientific.net/kem.645-646.313.
Повний текст джерелаWalker, Michael A. "Novel antiviral molecules." Drug Discovery Today 7, no. 20 (October 2002): 1065–66. http://dx.doi.org/10.1016/s1359-6446(02)02471-6.
Повний текст джерелаWestwell, Andrew D. "Novel antitumour molecules." Drug Discovery Today 8, no. 1 (January 2003): 47–50. http://dx.doi.org/10.1016/s1359-6446(02)02551-5.
Повний текст джерелаWestwell, Andrew D. "Novel antitumour molecules." Drug Discovery Today 8, no. 5 (March 2003): 229–31. http://dx.doi.org/10.1016/s1359-6446(03)02622-9.
Повний текст джерелаWestwell, A. "Novel antitumour molecules." Drug Discovery Today 8, no. 9 (May 1, 2003): 421–22. http://dx.doi.org/10.1016/s1359-6446(03)02676-x.
Повний текст джерелаWestwell, Andrew D. "Novel antitumour molecules." Drug Discovery Today 8, no. 15 (August 2003): 718–19. http://dx.doi.org/10.1016/s1359-6446(03)02776-4.
Повний текст джерелаWestwell, Andrew D. "Novel antitumour molecules." Drug Discovery Today 8, no. 20 (October 2003): 955–57. http://dx.doi.org/10.1016/s1359-6446(03)02834-4.
Повний текст джерелаWestwell, Andrew. "Novel antitumour molecules." Drug Discovery Today 6, no. 4 (February 2001): 215–16. http://dx.doi.org/10.1016/s1359-6446(00)01619-6.
Повний текст джерелаWestwell, Andrew. "Novel antitumour molecules." Drug Discovery Today 6, no. 9 (May 2001): 489–91. http://dx.doi.org/10.1016/s1359-6446(01)01755-x.
Повний текст джерелаWestwell, Andrew. "Novel antitumour molecules." Drug Discovery Today 6, no. 12 (June 2001): 648–49. http://dx.doi.org/10.1016/s1359-6446(01)01829-3.
Повний текст джерелаДисертації з теми "Novel Molecules"
Walsh, Anthony. "Novel methods to access bioactive molecules." Thesis, University of Huddersfield, 2015. http://eprints.hud.ac.uk/id/eprint/26947/.
Повний текст джерелаOdenthal, Katherine Jane Chemistry Faculty of Science UNSW. "Novel redox molecules for surface electrochemistry." Publisher:University of New South Wales. Chemistry, 2009. http://handle.unsw.edu.au/1959.4/43661.
Повний текст джерелаStrelko, Cheryl. "Novel Small Molecules and Tumor Cells." Thesis, Boston College, 2012. http://hdl.handle.net/2345/3778.
Повний текст джерелаThesis advisor: Eranthie Weerapana
Small molecules are of interest both as metabolites in tumor cell biology and as potential therapeutics in the fight against cancer. In this work, small molecules in both roles have been examined. Modulation of tumor cell metabolism holds promise as a strategy to combat cancer, and both glucose and glutamine have been identified as critical fuels for tumor cell growth and proliferation. However, the reason for glutamine addiction is poorly understood. The differential metabolism of glutamine and glucose was therefore examined using ¹³C labeling and NMR-based metabolomics in the VM-M3 tumor cell line, which requires both glucose and glutamine for survival and proliferation. In the course of this study, a novel mammalian metabolite itaconic acid was identified. Itaconic acid was detected in extracts and tissue culture media from the murine macrophage-derived tumor cell lines VM-M3 and RAW 264.7 as well as in primary macrophages. Production and secretion of itaconic acid was increased upon stimulation. LC-MS and NMR based metabolomics studies show that this metabolite is synthesized by the decarboxylation of cis-aconitate from the TCA cycle, and provided evidence for a novel mammalian homologue of the enzyme cis-aconitic decarboxylase. D-3-deoxy diC₈PI is a small molecule of interest as a potential cancer therapeutic. This compound was designed to induce apoptosis in tumor cells by competitively binding to the Akt PH domain and preventing Akt translocation. However, high resolution ³¹P field-cycling studies show that both D-3-deoxy diC₈PI and an inactive analogue L-3,5-dideoxy diC₈PI bind to the same site on the PH domain, which is distinct from the binding site of the ligand diC₈PI(3,4,5)P₃. This makes the aforementioned mechanism of cytotoxicity unlikely. Aggregation of the PH domain in the presence of soluble headgroup IP₆ was also observed, which may be related to a physiological function of this protein and invalidates at least one other binding assay. Investigation into alterations in signaling pathways in the MCF-7 breast cancer cell line showed that D-3-deoxy diC₈PI activates the p38MAPK pathway which results in CREB hyperphosphorylation. However, activation of this pathway appears to be compensatory and unrelated to the mechanism of action. D-3-deoxy diC₈PI also decreases levels of cyclin D1 and cyclin D3, which regulate the progression of the cell cycle. These decreases appear to be occurring at the transcriptional level rather than due to increased proteasomal degradation. The loss of these two proteins does not cause apoptosis in MCF-7 cells, but siRNA knockdown of specifically cyclin D1 inhibits proliferation. This is consistent with the cell cycle arrest observed upon D-3-deoxy diC₈PI treatment in these cells. These findings do not conclusively elucidate the mechanism of cytotoxicity of D-3-deoxy diC₈PI, but provide a characterization of some of its effects in the MCF-7 cell line which may be useful for further studies
Thesis (PhD) — Boston College, 2012
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
Adamson, R. D. "Novel methods for large molecules in quantum chemistry." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595361.
Повний текст джерелаSmith, Euan Christopher. "Ultrafast third-order nonlinearities in novel zwitterionic molecules." Thesis, Heriot-Watt University, 1998. http://hdl.handle.net/10399/599.
Повний текст джерелаDrayna, Garrett Korda. "Novel Applications of Buffer-Gas Cooling to Cold Atoms, Diatomic Molecules, and Large Molecules." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718757.
Повний текст джерелаChemical Physics
Tetteh, Kevin Kwaku Adjei. "Molecular characterisation of novel functionally important molecules of the model parasitic nematode, Toxocara canis." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/11455.
Повний текст джерелаNeri, Tommaso. "Novel organic semiconducting small molecules for X-ray detection." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14809/.
Повний текст джерелаShen, Dong. "Syntheses and mesophase characterizations of novel bent core molecules." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=961481889.
Повний текст джерелаDattani, Hema. "Novel Tripodal Receptors Designed to Recognize Anionic Guest Molecules." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489428.
Повний текст джерелаКниги з теми "Novel Molecules"
Modeling marvels: Computational anticipation of novel molecules. [Dordrecht]: Springer, 2008.
Знайти повний текст джерелаBanik, Bimal K., ред. β-Lactams: Unique Structures of Distinction for Novel Molecules. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-33188-6.
Повний текст джерелаAli, Sami Mohammed. Relaxation studies of various molecules using a novel modulated temperature technique. Salford: Universityof Salford, 1985.
Знайти повний текст джерелаMolecular modeling for the design of novel performance chemicals and materials. Boca Raton: CRC Press, 2012.
Знайти повний текст джерелаM, Blow D., Fersht Alan 1943-, Winter G, and Royal Society (Great Britain), eds. Design, construction, and properties of novel protein molecules: Proceedings of a Royal Society discussion meeting, held on 5 and 6 June 1985. London: Royal Society, 1986.
Знайти повний текст джерелаAstrid, Gräslund, Rigler Rudolf, and Widengren Jerker, eds. Single molecule spectroscopy in chemistry, physics and biology: Nobel Symposium. Heidelburg [Germany]: Springer, 2010.
Знайти повний текст джерелаRudolf, Rigler, Orrit M. 1956-, and Basché T, eds. Single molecule spectroscopy: Nobel conference lectures. Berlin: Springer, 2001.
Знайти повний текст джерелаBenfenati, Fabio, Enzo Di Fabrizio, and Vincent Torre, eds. Novel Approaches for Single Molecule Activation and Detection. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43367-6.
Повний текст джерелаPruzanski, Waldemar, and Peter Vadas, eds. Novel Molecular Approaches to Anti-Inflammatory Therapy. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8.
Повний текст джерелаTreacher, Kevin Edward. Molecular and polymeric assemblies of novel substituted phthalocyanines. Manchester: University of Manchester, 1995.
Знайти повний текст джерелаЧастини книг з теми "Novel Molecules"
Vukelic, Valeria Lourdes, and Marcelo Orias. "Novel Molecules." In Chronic Kidney Disease and Hypertension, 47–55. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1982-6_5.
Повний текст джерелаHorstkorte, Rüdiger, Bettina Büttner, Kaya Bork, Navdeep Sahota, Sarah Sabir, Laura O’Regan, Joelle Blot, et al. "NSP, Novel Serine Protease." In Encyclopedia of Signaling Molecules, 1274. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100942.
Повний текст джерелаKalia, Vipin Chandra. "Mining Metagenomes for Novel Bioactive Molecules." In Mining of Microbial Wealth and MetaGenomics, 1–9. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5708-3_1.
Повний текст джерелаSinghal, Paavan, Anita Rani Gill, Preeti K. Sharma, Rakesh Kumar, Nabin Bhusal, Amandeep Kaur, and Pooja Sharma. "Aptamers: Novel Therapeutic and Diagnostic Molecules." In Aptamers, 73–89. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-8836-1_5.
Повний текст джерелаFassina, Giorgio. "Complementary Peptides as Recognition Molecules." In Novel Molecular Approaches to Anti-Inflammatory Therapy, 109–20. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8_11.
Повний текст джерелаIgnat’ev, Nikolai, Sergii Datsenko, and Elena Smertenko. "Electrochemical Introduction of Fluorinated Substituents into Organic Molecules." In Novel Trends in Electroorganic Synthesis, 305–8. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_92.
Повний текст джерелаHochuli, E. "Genetically Designed Affinity Chromatography Using a Novel Metal Chelate Absorbent." In Biologically Active Molecules, 217–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74582-9_10.
Повний текст джерелаDeshmukh, Sunil K., Manish K. Gupta, Ved Prakash, and M. Sudhakara Reddy. "Fungal Endophytes -a Novel Source of Cytotoxic Compounds." In Bioactive Molecules in Food, 1–62. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-76900-4_13-1.
Повний текст джерелаKumar, Vinod, Shalini Rai, Pallavi Gaur, and Tayaba Fatima. "Endophytic Fungi: Novel Sources of Anticancer Molecules." In Advances in Endophytic Research, 389–422. New Delhi: Springer India, 2013. http://dx.doi.org/10.1007/978-81-322-1575-2_20.
Повний текст джерелаMacCalman, C. D., A. Omigbodun, X. C. Tian, J. E. Fortune, E. E. Furth, C. Coutifaris, and J. F. Strauss. "Novel Cell Adhesion Molecules: Roles in Implantation?" In The Endometrium as a Target for Contraception, 137–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-10323-4_7.
Повний текст джерелаТези доповідей конференцій з теми "Novel Molecules"
Abney, Josh, and Matthew Dietrich. "LASER ABLATION MOLECULAR SPECTROSCOPY OF NOVEL BARIUM MOLECULES." In 2020 International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2020. http://dx.doi.org/10.15278/isms.2020.rk09.
Повний текст джерелаLee, Hongki, Kyungnam Kang, Kentaro Mochizuki, Changhun Lee, Hajun Yoo, Woo Joong Rhee, Gwiyeong Moon, et al. "Plasmon-enhanced Raman microscopy of cell membrane molecules." In Novel Techniques in Microscopy. Washington, D.C.: OSA, 2021. http://dx.doi.org/10.1364/ntm.2021.nm3c.2.
Повний текст джерелаLin, Linhan, Xiaolei Peng, and Yuebing Zheng. "Manipulating Fano coupling in all-dielectric meta-molecules." In Novel Optical Materials and Applications. Washington, D.C.: OSA, 2019. http://dx.doi.org/10.1364/noma.2019.now1b.4.
Повний текст джерелаde Valk, Kim S., and Alexander L. Vahrmeijer. "The clinical translation of novel near-infrared fluorophores for fluorescence guided surgery." In Molecular-Guided Surgery: Molecules, Devices, and Applications V, edited by Brian W. Pogue and Sylvain Gioux. SPIE, 2019. http://dx.doi.org/10.1117/12.2516413.
Повний текст джерелаHenderson, Eric R., Alisha V. DSouza, Keith D. Paulsen, and Brian W. Pogue. "Novel applications of near-infrared fluorescence imaging in orthopaedic surgery (Conference Presentation)." In Molecular-Guided Surgery: Molecules, Devices, and Applications III, edited by Brian W. Pogue and Sylvain Gioux. SPIE, 2017. http://dx.doi.org/10.1117/12.2257091.
Повний текст джерелаArrondo, C. "In-situ coalescence of aligned C60 molecules in Peapods." In ELECTRONIC PROPERTIES OF NOVEL NANOSTRUCTURES: XIX International Winterschool/Euroconference on Electronic Properties of Novel Materials. AIP, 2005. http://dx.doi.org/10.1063/1.2103881.
Повний текст джерелаBarth, Connor W., and Summer L. Gibbs. "The advantages and disadvantages of novel contrast agent types for fluorescence guided surgery." In Molecular-Guided Surgery: Molecules, Devices, and Applications VIII, edited by Summer L. Gibbs, Brian W. Pogue, and Sylvain Gioux. SPIE, 2022. http://dx.doi.org/10.1117/12.2613182.
Повний текст джерелаFink, H. W. "Electrical conduction through DNA molecules." In The 14th international winterschool on electronic properties of novel materials - molecular nanostructures. AIP, 2000. http://dx.doi.org/10.1063/1.1342554.
Повний текст джерелаFarnam, Richard. "IS-001: investigating a novel compound for fluorescent ureteral identification during robotic hysterectomy (Conference Presentation)." In Molecular-Guided Surgery: Molecules, Devices, and Applications IV, edited by Greg Biggs, Brian W. Pogue, and Sylvain Gioux. SPIE, 2018. http://dx.doi.org/10.1117/12.2291974.
Повний текст джерелаXie, Jian-Fei, and Bing-Yang Cao. "Molecular Dynamics Study on Fluid Flow in Nanochannels With Permeable Walls." In ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/mnhmt2016-6421.
Повний текст джерелаЗвіти організацій з теми "Novel Molecules"
Koeffler, H. P. Identification of Novel Secreted Molecules of Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, June 1999. http://dx.doi.org/10.21236/ada371233.
Повний текст джерелаLaws, David Douglas. Novel nuclear magnetic resonance techniques for studying biological molecules. Office of Scientific and Technical Information (OSTI), June 2000. http://dx.doi.org/10.2172/970017.
Повний текст джерелаChamovitz, Daniel A., and Zhenbiao Yang. Chemical Genetics of the COP9 Signalosome: Identification of Novel Regulators of Plant Development. United States Department of Agriculture, January 2011. http://dx.doi.org/10.32747/2011.7699844.bard.
Повний текст джерелаMason, Ralph P. Breast Tumor pH: Design, Evaluation, and Application of Novel Reporter Molecules. Fort Belvoir, VA: Defense Technical Information Center, October 2001. http://dx.doi.org/10.21236/ada403387.
Повний текст джерелаMason, Ralph P. Breast Tumor pH: Design Evaluation and Application of Novel Reporter Molecules. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada411792.
Повний текст джерелаLi, Chenglong, James Fuchs, and Jiayuh Lin. Novel Small Molecules Disabling the IL-6/IL-6R/GP130 Heterohexamer Complex. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada606135.
Повний текст джерелаCalin, George A., Shuxing Zhang, and Waldemar Priebe. Targeting Micrornas With Small Molecules: A Novel Approach to Treating Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2010. http://dx.doi.org/10.21236/ada538185.
Повний текст джерелаLi, Chenglong, James Fuchs, and Jiayuh Lin. Novel Small Molecules Disabling the IL-6/IL-6R/GP130 Heterohexamer Complex. Fort Belvoir, VA: Defense Technical Information Center, October 2012. http://dx.doi.org/10.21236/ada584824.
Повний текст джерелаCalin, George A., Shuxing Zhang, and Waldemar Priebe. Targeting MicroRNAs with Small Molecules a Novel Approach to Treating Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2011. http://dx.doi.org/10.21236/ada555163.
Повний текст джерелаForsythe, Eric, Jianmin Shi, and David Morton. Next Generation Highly Conducting Organic Films Using Novel Donor-Acceptor Molecules for Opto-Electronic Applications. Fort Belvoir, VA: Defense Technical Information Center, June 2009. http://dx.doi.org/10.21236/ada499643.
Повний текст джерела