Добірка наукової літератури з теми "Novel marker"

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Статті в журналах з теми "Novel marker"

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Chen, Yingying, Jiafan Yang, Cunlei Cai, Junjie Shi, Yongxiang Song, Junying Ma, and Jianhua Ju. "Development of Marker Recycling Systems for Sequential Genetic Manipulation in Marine-Derived Fungi Spiromastix sp. SCSIO F190 and Aspergillus sp. SCSIO SX7S7." Journal of Fungi 9, no. 3 (February 26, 2023): 302. http://dx.doi.org/10.3390/jof9030302.

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Marine-derived fungi are emerging as prolific workhorses of structurally novel natural products (NPs) with diverse bioactivities. However, the limitation of available selection markers hampers the exploration of cryptic NPs. Recyclable markers are therefore valuable assets in genetic engineering programs for awaking silent SM clusters. Here, both pyrG and amdS-based recyclable marker cassettes were established and successfully applied in marine-derived fungi Aspergillus sp. SCSIO SX7S7 and Spiromastix sp. SCSIO F190, respectively. Using pyrG recyclable marker, a markerless 7S7-∆depH strain with a simplified HPLC background was built by inactivating a polyketide synthase (PKS) gene depH and looping out the pyrG recyclable marker after depH deletion. Meanwhile, an amdS recyclable marker system was also developed to help strains that are difficult to use pyrG marker. By employing the amdS marker, a backbone gene spm11 responsible for one major product of Spiromastix sp. SCSIO F190 was inactivated, and the amdS marker was excised after using, generating a relatively clean F190-∆spm11 strain for further activation of novel NPs. The collection of two different recycle markers will guarantee flexible application in marine-derived fungi with different genetic backgrounds, enabling the exploitation of novel structures in various fungi species with different genome mining strategies.
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Yongbin, Qi, Patcharaporn Summat, Natjaree Panyawut, Kannika Sikaewtung, Khanittha Ditthab, Keasinee Tongmark, Sriprapai Chakhonkaen, et al. "Identification of Rice Accessions Having Cold Tolerance at the Seedling Stage and Development of Novel Genotypic Assays for Predicting Cold Tolerance." Plants 12, no. 1 (January 3, 2023): 215. http://dx.doi.org/10.3390/plants12010215.

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Rice is susceptible to cold stress at the seedling stage, which can delay growth and decrease yield. We evaluated 187 rice accessions for cold tolerance at the seedling stage and developed genotypic assays for three markers. All japonica (20/20) and 20/140 indica accessions were highly cold tolerant. Two SNP markers specific for COLD1 and LOC_Os10g34840 were practical to use by normal agarose gel. The SNP marker specific for COLD1 was highly specific for predicting cold tolerance. However, the sensitivity of this marker was low as several cold-tolerant indica accessions lacked the cold-tolerant allele. The LOC_Os10g34840 marker was slightly more sensitive than the COLD1 marker for predicting highly cold-tolerant accessions. An insertion/deletion variant in the NAC6 gene was identified as a novel cold tolerance marker. The NAC6 marker predicted more highly cold-tolerant accessions compared with the other two markers. The SNP marker specific for LOC_Os10g34840 and the NAC6 marker were present in several tested subgroups, suggesting their wide effects and distribution. The three markers combined predicted the most highly cold-tolerant accessions, indicating that the marker combination is superior for applications such as marker-assisted breeding. The cold-tolerant accessions and the genotypic marker assays will be useful for future rice breeding.
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de Ridder, Mischa, Lara C. Gerbrandy, Theo M. de Reijke, Karel A. Hinnen, and Maarten C. C. M. Hulshof. "BioXmark® liquid fiducial markers for image-guided radiotherapy in muscle invasive bladder cancer: a safety and performance trial." British Journal of Radiology 93, no. 1111 (July 2020): 20200241. http://dx.doi.org/10.1259/bjr.20200241.

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Objective: This study evaluated the performance of the novel liquid fiducial marker (BioXmark®) in IGRT for bladder cancer. Methods: 20 patients with muscle invasive bladder cancer were entered in this prospective, single center, Phase I-II study. The novel BioXmark® liquid markers were injected around the tumor using a flexible cystoscopy. Visibility and stability of the markers were evaluated on planning-CT and CBCT. Prospectively defined threshold for success was set at a visibility of 75%. Results: In total, 76 markers were implanted in 20 patients. Of those, 60 (79% 95% CI ± 9%) were visible on CT scan. Due to the learning curve of the technique, the visibility improved in the last 75% of patients (86% visibility) compared to the first 25% of patients with 58% visibility. Concerning stability of the BioXmark® marker, all visible markers after CT acquisition were still detectable at the last CBCT without displacement. In 15/20 (75%) of the patients, three or more markers were visible on CT. No BioXmark® related adverse events were reported. Conclusion: The success rate of this novel fiducial marker was 79%, which is above the prospectively defined threshold rate. A distinct learning curve of the injection of the liquid marker was seen over the study period. The marker showed sustained visibility and positional stability during treatment phases and also appears to be safe and easy to inject. Advances in knowledge: This novel liquid BioXmark® marker seems to be a very promising tool in daily-adaptive IGRT for bladder preserving chemoradiotherapy in muscle invasive bladder cancer.
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Luukinen, Jean-Marc, Daniel Aalto, Jarmo Malinen, Naoko Niikuni, Jani Saunavaara, Päivi Jääsaari, Antti Ojalammi, Riitta Parkkola, Tero Soukka, and Risto-Pekka Happonen. "A Novel Marker Based Method to Teeth Alignment in MRI." Measurement Science Review 18, no. 2 (April 1, 2018): 79–85. http://dx.doi.org/10.1515/msr-2018-0012.

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AbstractMagnetic resonance imaging (MRI) can precisely capture the anatomy of the vocal tract. However, the crowns of teeth are not visible in standard MRI scans. In this study, a marker-based teeth alignment method is presented and evaluated. Ten patients undergoing orthognathic surgery were enrolled. Supraglottal airways were imaged preoperatively using structural MRI. MRI visible markers were developed, and they were attached to maxillary teeth and corresponding locations on the dental casts. Repeated measurements of intermarker distances in MRI and in a replica model was compared using linear regression analysis. Dental cast MRI and corresponding caliper measurements did not differ significantly. In contrast, the marker locationsin vivodiffered somewhat from the dental cast measurements likely due to marker placement inaccuracies. The markers were clearly visible in MRI and allowed for dental models to be aligned to head and neck MRI scans.
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Shapoval, S. D., I. L. Savon, L. V. Vasylevska, and M. M. Sofilkanych. "PRESEPSIN IS A NOVEL HIGHLY EFFECTIVE SEPSIS MARKER(REVIEW)." Modern medical technologies 44, no. 1 (March 1, 2020): 84–87. http://dx.doi.org/10.34287/mmt.1(44).2020.13.

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Abstract In this review the most effective markers of septic process like Procalcitonin, C-reactive protein, and cytokines compared to the new marker – Presepsin (PSP) are analyzed. At sepsis initiation, PSP increases 30 to 60 minutes after the onset of systemic infection. PSP levels at admission to the hospital predict the risk of adverse and adverse effects that other markers used for the diagnosis of sepsis do not have.
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Mortensen, Ole Hartvig, Anders Rinnov Nielsen, Christian Erikstrup, Peter Plomgaard, Christian Philip Fischer, Rikke Krogh-Madsen, Birgitte Lindegaard, Anne Marie Petersen, Sarah Taudorf, and Bente Klarlund Pedersen. "Calprotectin — A Novel Marker of Obesity." PLoS ONE 4, no. 10 (October 12, 2009): e7419. http://dx.doi.org/10.1371/journal.pone.0007419.

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Ordóñez, Nelson G. "Podoplanin: A Novel Diagnostic Immunohistochemical Marker." Advances in Anatomic Pathology 13, no. 2 (March 2006): 83–88. http://dx.doi.org/10.1097/01.pap.0000213007.48479.94.

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Rudnicka, M., D. Hinton, and C. A. Miller. "A NOVEL MARKER FOR OLIGODENDROGLIAL CELLS." Journal of Neuropathology and Experimental Neurology 48, no. 3 (May 1989): 363. http://dx.doi.org/10.1097/00005072-198905000-00193.

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Volk, Andrea L., and Gene P. Siegal. "MDA-7: a novel prognostic marker?" Advances in Anatomic Pathology 9, no. 5 (September 2002): 323. http://dx.doi.org/10.1097/00125480-200209000-00007.

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Deschamps, Kevin, Philip Roosen, Ivan Birch, Bart Dingenen, Herman Bruyninckx, Kaat Desloovere, Erwin Aertbelien, and Filip Staes. "A Novel Device for Standardizing Marker Placement at the Calcaneus." Journal of the American Podiatric Medical Association 104, no. 1 (January 1, 2014): 43–49. http://dx.doi.org/10.7547/0003-0538-104.1.43.

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Background The determination of anatomical reference frames in the rearfoot during three-dimensional multisegment foot modeling has been hindered by a variety of factors. One of these factors is related to the difficulty in palpating, or the absence of, anatomical landmarks. A novel device (the Calcaneal Marker Device) aimed at standardizing marker placement at the calcaneus was, therefore, developed and evaluated for its reliability. Methods Throughout a random repeated-measures design, the repeatability of calcaneal marker placement was evaluated for two techniques: manual placement and placement using the Calcaneal Marker Device. Translational changes after marker placement and the clinical effect on intersegment angle calculation were quantified. Results Intraobserver variability was greater in therapist 2 (<5.3 mm) compared with therapist 1 (<2.9 mm). Intraobserver variability was also found to be less than 1.6 mm throughout use of the device. Interobserver variability was found to be significantly higher for the position of markers placed manually (5.8 mm), whereas with the Calcaneal Marker Device, the variability remained lower (<1.3 mm). The effect on the computed intersegment angles followed a similar trend, with variability of 0.4° to 4.0° and 1.0° to 8.7° for CMD and manual placement, respectively. Conclusions These findings suggest that variations in marker placement are considerably reduced when the novel Calcaneal Marker Device is used, possibly toward the limits dictated by the fine motor skills of therapists and tissue artifacts.
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Дисертації з теми "Novel marker"

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Kon, Samantha Swee Chin. "Habitual gait speed : a novel prognostic marker in COPD?" Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/56925.

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Forced expiatory volume in one second (FEV1) is the most widely accepted marker in COPD. However, COPD is now well recognised as a multisystem and heterogeneous disease, and it is unlikely that a single marker could reflect the complex range of observed pathophysiologic changes. Exercise intolerance is a common symptom in COPD, and reflects both lung and skeletal muscle dysfunction. Logistical issues often mean physical performance is not routinely measured objectively in all clinical settings. Gait speed is an easy, quick to perform established measure of physical performance in the elderly, and has been recommended as a “vital sign” or “global marker of well-being” that reflects biological rather than chronological age. Functional decline is common to both ageing and COPD but gait speed has not been validated in COPD. In 586 patients with stable COPD, usual gait speed over 4 metres (4MGS) had excellent reliability and showed concurrent validity with well-established measures in COPD. Stratification according to slow 4MGS identified significant impairments in exercise capacity and poor health-related quality of life. Subsequent studies showed that 4MGS was responsive to intervention with pulmonary rehabilitation (n=301) and longitudinal decline at one year (n=162). Using both distribution- and anchor-based approaches the minimum clinically important difference was estimated to be 0.11ms-1. In a cohort of patients with stable COPD (n=402), slower 4MGS was associated with significantly increased risk of all-cause mortality at three years, and provided prognostic information independent of FEV1. In a prospective cohort of 213 patients admitted to hospital with an acute exacerbation of COPD, slower 4MGS was associated with significantly increased odds of all-cause readmission at 90 days. The 4MGS is a reliable measure of physical performance that has potential utility as a simple assessment tool to provide a more comprehensive assessment of patients with COPD.
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Holtkötter, Hannah [Verfasser]. "Novel marker systems for forensic body fluid identification / Hannah Holtkötter." Ulm : Universität Ulm, 2018. http://d-nb.info/1166756602/34.

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Gahunia, Harpal Kaur. "A novel cartilage biochemical marker (CM-1), isolation, purification and characterization." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0020/NQ45732.pdf.

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Juhász, Margit Lai Wun. "Murine CD248 and its cytoplasmic domain : characterising a novel tumour and inflammation marker." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42573.

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CD248 is a member of a family of transmembrane glycoproteins containing an N-terminal C-type lectin-like domain. This family includes thrombomodulin and CD93, proteins known to modulate immunity, cell proliferation and homeostasis. CD248 is expressed in perivascular and stromal cells, during embryonic development and post-natally during inflammation and cancer. In the mesenchymal compartment of most normal adult tissues, CD248 expression is not detectable. It is believed that CD248 is involved in cross-talk between endothelial cells and pericytes, thereby playing a role in growth, metastasis and angiogenesis associated with the development of tumours and inflammatory lesions. Intracellular signaling, mediated via the cytoplasmic domain of CD248, promotes tumour growth and inflammation. CD248 knock-out mice and mice expressing CD248 lacking the cytoplasmic domain were resistant to tumour growth and inflammatory arthritis. Although signaling pathways have not been delineated, examination of the cytoplasmic domain of CD248 reveals three highly conserved putative phosphorylation sites and a PDZ-binding motif. We hypothesised that these structural features are important for CD248 function. We generated a variety of murine CD248 pcDNA constructs that encode CD248 with mutations in the cytoplasmic domain. We confirmed that all the mutants were transcribed and translated. Mutant proteins were expressed on the cell surface, in a similar manner to wildtype CD248. Introduction of some mutant forms CD248 into cells caused CD248 to exhibit different intracellular localisation and induced changes in cellular morphology compared to wildtype. Limited functional studies demonstrated CD248-dependent alterations in cellular MMP-9 production. The findings underline an important role of CD248’s cytoplasmic domain in regulating cellular morphology and function that may impact its role in health and disease. Extracellular interacting partners for CD248 have been previously described. Searches for intracellular partners interacting with the cytoplasmic domain have been less successful. Our results strongly suggest that these exist. Co-immunoprecipitation studies have revealed several putative interacting proteins that set the stage for future confirmatory and functional analyses. The cytoplasmic domain of CD248 is important to study as it holds much promise as a therapeutic target for proliferative disorders. The information gathered in this project may be used to delineate clinically relevant CD248 signaling pathways.
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Лобода, Андрій Миколайович, Андрей Николаевич Лобода, Andrii Mykolaiovych Loboda, and M. Tutuola. "Cystatin C - A novel marker of kinder injury in the newborns with asphyxia." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32303.

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In clinical practice, kidney injury is detected when serum creatinine concentrations increase over a short period of time, with or without oliguria. To assess renal function in neonates is used determination of glomerular filtration rate (GFR) after creatinine. But creatinine concentration is not a decisive marker. Changes in serum creatinine may be influenced by other factors, which are not directly related to kidney damage, such as age, sex, body mass and nutritional status. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/32303
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Akarca, Ayse. "Immunohistochemical studies for identification of biomarkers in haematological malignancies: An approach for potential novel therapeutic targets." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1127626.

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Lymphoid neoplasms are a subgroup of haematological malignancies that affect circulating lymphocytes. The clinical and biological heterogeneity of lymphoid neoplasms can lead to difficulty in accurate diagnosis in this group of diseases. The advancement in effective and feasible detection platforms has enabled novel biomarkers to improve diagnosis and prognosis, in addition to assist in patient stratification and personalised treatments for these diseases. Although there have been improvements in high-throughput diagnostic techniques, the conventional immunohistochemistry (IHC) remains the most widely used platform for biomarker assessment in the field of tissue pathology. As this conventional technique has certain limitations, multiplex IHC (MIHC) approaches have found ways to overcome these challenges, therefore becoming the main focus of immunotherapy for lymphoid neoplasms. This particular effective and proficient technology can simultaneously target multiple molecule/protein of interest within the tumor microenvironment to determine the status of immune cell activation and the presence of protein expression. MIHC is advantageous in providing information about the underlying immune evasion mechanisms, which play a vital role in the development of prognostic and diagnostic biomarkers. This thesis focuses on the novel use of IHC/MIHC approaches and their current role in biomarker development to be used in diagnosis, prognosis, and the potential treatment strategies within haematological malignancies in specific lymphoid neoplasms.
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Traore, Karim. "Characterization of novel rice germplasm from West Africa and genetic marker associations with rice cooking quality." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4146.

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Genetic resource enhancement is the foundation of any good breeding program. Landraces from West Africa, interspecifics between Oryza sativa and Oryza glaberrima and improved lines from the West African Rice Development Association and other research centers were introduced to the Beaumont Rice Research center for in situ evaluation and characterization. Beside the introduction of seeds, milled samples were also introduced for grain chemistry analysis. Field evaluation combined with physicochemical and molecular characterization revealed unique characteristics among African germplasm. New rice for Africa (NERICA) lines performed well in the USA environment. Varieties like Nerica 2, Nerica 3, Nerica 4, and Nerica 5 need more attention because of their superior performance in yield and grain quality. Landraces did not perform well due to their height and late maturity and their resulting problems with lodging. The rapid visco analyzer RVA profiles showed that the cultivar Jaya has unusually strong paste viscosity features. Comparing West Africa samples grown in Cote d’Ivoire with those grown in Texas, parameters like AA, ASV, Hot, Cool, and CT were not stongly affected by the environment. According to the Stbk value, cultivars grown in Cote d’Ivoire will cook softer than when they were grown in Texas. The lack of the environmental effect is somewhat surprising considering the difference in latitude, soil types, weather patterns, and management practices between the two locations. Apparent amylose is a key element to characterize a rice cultivar; however certain varieties like Cocodrie and Dixiebelle have similar apparent amylose content but dramatically different functional qualities. A population derived from Cocodrie and Dixiebelle was developed for genotypic and phenotypic analysis of grain chemistry traits that affect functionality. It was concluded that the amount of soluble amylose in the grain had a significant effect on flour pasting properties, even when total apparent amylose content did not vary. Marker association studies revealed that the Waxy microsatellite and the Waxy exon 10 SNP markers were associated with soluble amylose content and RVA characteristics. These markers will speed up the development of new rice cultivars with desirable quality characteristics in West Africa and in the USA.
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Gasca, Stéphan Emmanuel. "Cordon-bleu, a novel murine developmental marker gene isolated by a gene trap approach." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0020/NQ27650.pdf.

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Limb, Marie. "MUC1 mucin as a tumour marker : investigations into a novel immunoassay and reagent development." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395584.

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Rolan, Paul Edward. "The exploratory clinical development of tucaresol, an antisickling agent, using a novel surrogate marker /." Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09M.D/09m.dr744.pdf.

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Thesis (M.D.)--University of Adelaide, Dept of Clinical and Experimental Pharmacology, 1995.
Copies of author's previously published articles inserted. Describes the exploratory clinical development of tucaresol, consisting of three studies performed on humans and subsequent in vitro and animal studies investigating the possible effects on the immune system. Demostrates that rational drug design may be an efficient way of selecting potential therapeutic candidates.
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Книги з теми "Novel marker"

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Cerullo, Dante. Identification of a novel diagnostic marker for viral myocarditis using cDNA microarrays. Ottawa: National Library of Canada, 2003.

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2

Gasca, Stéphan Emmanuel. Cordon-bleu: A novel murine developmental marker gene isolated by a gene trap approach. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1997.

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Tine, Robert. Black market: A novel. New York: St. Martin's Press, 1992.

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Lee, Helen Elaine. Water marked: A novel. New York: Scribner, 1999.

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Vachss, Andrew H. Mask market: A Burke novel. New York: Pantheon Books, 2006.

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Scott, Inara. The marked: A Talents novel. New York: Hyperion Books, 2011.

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Scott, Inara. The marked: A Talents novel. New York: Hyperion Books, 2011.

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Crownover, Jay. Jet: A marked men novel. New York, NY: William Morrow, an imprint of HarperCollinsPublishers, 2013.

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Rachel, Randall. 2015 novel & short story writer's market. Edited by Writer's Digest Books (Firm). 3rd ed. Cincinnati, Ohio: Writer's Digest Books, 2014.

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Demon marked: A demon bound novel. New York: New American Library, 2011.

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Частини книг з теми "Novel marker"

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Biller, S., D. Baumgarten, and J. Haueisen. "Magnetic Marker Monitoring: A novel approach for magnetic marker design." In XII Mediterranean Conference on Medical and Biological Engineering and Computing 2010, 260–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13039-7_65.

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Boopathi, N. Manikanda. "Curtain Raiser to Novel MAS Platforms." In Genetic Mapping and Marker Assisted Selection, 193–244. India: Springer India, 2012. http://dx.doi.org/10.1007/978-81-322-0958-4_10.

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Mancuso, Patrizia, Angelica Calleri, Cristina Cassi, Alberto Gobbi, Manuela Capillo, Giancarlo Pruneri, Giovanni Martinelli, and Francesco Bertolini. "Circulating Endothelial Cells as a Novel Marker of Angiogenesis." In Advances in Experimental Medicine and Biology, 83–97. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0169-5_9.

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Tao, Xingzhen, Haiping Li, and Lei Deng. "Research on Self-driving Lane and Traffic Marker Recognition Based on Deep Learning." In Exploration of Novel Intelligent Optimization Algorithms, 112–23. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-4109-2_12.

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Kawasaki, Toshisuke, Motohiro Nonaka, and Nobuko Kawasaki. "Mannan-Binding Protein (MBP)-Ligand Glycans: Novel Tissue Marker Tissue tumor marker for Colorectal Carcinomas." In Glycoscience: Biology and Medicine, 1021–28. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54841-6_60.

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De Meo, Meghan L., Muhammad H. Shahzad, and Jonathan D. Spicer. "Visualizing NETosis Using a Novel Neutrophil Extracellular Trap-Specific Marker." In Methods in Molecular Biology, 71–80. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2914-7_5.

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Tao, Quan Zhou, Makoto Kimura, and Isamu Yamaguchi. "A novel dominant drug resistance marker for transformation of Pyricularia oryazae." In Biotechnology in Agriculture, 457–61. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1779-1_90.

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Roslind, Anne, and Julia S. Johansen. "YKL-40: A Novel Marker Shared by Chronic Inflammation and Oncogenic Transformation." In Methods in Molecular Biology, 159–84. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-447-6_7.

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Park, Jun-Kyung, Seung-Hwan Lee, Songhee Han, Jin-Cheol Kim, Young Cheol, and Brian McSpadden Gardener. "Marker-Assisted Selection of Novel Bacteria Contributing to Soil-Borne Plant Disease Suppression." In Molecular Microbial Ecology of the Rhizosphere, 637–42. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118297674.ch60.

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Liu, Xu, David Doermann, Huiping Li, K. C. Lee, Hasan Ozdemir, and Lipin Liu. "A Novel 2D Marker Design and Application for Object Tracking and Event Detection." In Advances in Visual Computing, 248–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-89639-5_24.

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Тези доповідей конференцій з теми "Novel marker"

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Li, Yun, Yimin Chen, Renmiao Lu, Deyi Ma, and Qiming Li. "A novel marker system in augmented reality." In 2012 2nd International Conference on Computer Science and Network Technology (ICCSNT). IEEE, 2012. http://dx.doi.org/10.1109/iccsnt.2012.6526185.

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Hsieh, W. F., Henry Lin, Vincent Chen, Irene Ou, and Y. S. Lou. "The Investigation of Fluorine Induced Novel Probe Marker Discoloration." In ISTFA 2018. ASM International, 2018. http://dx.doi.org/10.31399/asm.cp.istfa2018p0413.

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Abstract This paper describes the investigation of donut-shaped probe marker discolorations found on Al bondpads. Based on SEM/EDS, TEM/EELS, and Auger analysis, the corrosion product is a combination of aluminum, fluorine, and oxygen, implying that the discolorations are due to the presence of fluorine. Highly accelerated stress tests simulating one year of storage in air resulted in no new or worsening discolorations in the affected chips. In order to identify the exact cause of the fluorine-induced corrosion, the authors developed an automated inspection system that scans an entire wafer, recording and quantifying image contrast and brightness variations associated with discolorations. Dark field TEM images reveal thickness variations of up to 5 nm in the corrosion film, and EELS line scan data show the corresponding compositional distributions. The findings indicate that fluorine-containing gases used in upstream processes leave residues behind that are driven in to the Al bondpads by probe-tip forces and activated by the electric field generated during CP testing. The knowledge acquired has proven helpful in managing the problem.
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Liang, Yueqiang, Hongbing Xu, Baosheng Li, and Hongsheng Li. "A Novel Non-External Marker 4D-CT Sorting Algorithm." In 2010 International Conference on Biomedical Engineering and Computer Science (ICBECS). IEEE, 2010. http://dx.doi.org/10.1109/icbecs.2010.5462429.

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Ling, Chen, Jing Zhao, and Wenjun Zhang. "DR-Marker: A Novel Diminishing-Reality-Based AR Registration." In 2013 Seventh International Conference on Image and Graphics (ICIG). IEEE, 2013. http://dx.doi.org/10.1109/icig.2013.145.

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Liu, Jiamin, Lexiang An, Yan Chang, and Dan Yang. "A novel registration method based on triangular pattern marker." In 2013 IEEE Conference Anthology. IEEE, 2013. http://dx.doi.org/10.1109/anthology.2013.6784890.

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"A NOVEL APPROACH TO ACHIEVE ROBUSTNESS AGAINST MARKER OCCLUSION." In International Conference on Computer Vision Theory and Applications. SciTePress - Science and and Technology Publications, 2009. http://dx.doi.org/10.5220/0001789904780483.

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7

Wang, Yanlu, Feng He, Zaihong Hou, Xu Jing, and Yilun Cheng. "Research on the algorithm of marker center positioning under the occlusion of thermoplastic film." In Eighth Symposium on Novel Photoelectronic Detection Technology and Applications, edited by Shining Zhu, Qifeng Yu, Junhong Su, Lianghui Chen, and Junhao Chu. SPIE, 2022. http://dx.doi.org/10.1117/12.2624221.

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Nguyen, Minh, and Albert Yeap. "StereoTag: A novel stereogram-marker-based approach for Augmented Reality." In 2016 23rd International Conference on Pattern Recognition (ICPR). IEEE, 2016. http://dx.doi.org/10.1109/icpr.2016.7899776.

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Bousaid, Alexandre, Theodoros Theodoridis, and Samia Nefti-Meziani. "Introducing a novel marker-based geometry model in monocular vision." In 2016 13th Workshop on Positioning, Navigation and Communications (WPNC). IEEE, 2016. http://dx.doi.org/10.1109/wpnc.2016.7822857.

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Parri, Matteo, Susanna Campagnoli, Alberto Grandi, Elisa D. Camilli, Valentina Farini, Serenella Eppenberger, Paola Chiarugi, et al. "Abstract 1769: A novel potential cancer marker and therapeutic target." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1769.

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Звіти організацій з теми "Novel marker"

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Henry, Michael. Novel Biophysical Marker of Aggressive Prostate Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, June 2013. http://dx.doi.org/10.21236/ada581867.

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Serrero, Ginette. Novel Growth Factor as Prognostic Marker for Estrogen-Independence in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2003. http://dx.doi.org/10.21236/ada424094.

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3

Rosenberg, Carol L. Allele Imbalance or Loss of Heterozygosity in Normal-Appearing Breast Epithelium as a Novel Marker to Predict Future Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2007. http://dx.doi.org/10.21236/ada474710.

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Zheng, Pan. Development of a Novel Prognostic Marker to Link a Potential Tumor Suppressor Gene at Chromosome 6q to Aberrant Signal Transduction Pathway in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2005. http://dx.doi.org/10.21236/ada443032.

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Zamir, Dani, and Steven Tanksley. Fine Mapping and Genetic Interactions of Nearly-Isogenic Allelic Series Representing Yield and Quality QTLs Derived from Wild Tomato Species. United States Department of Agriculture, July 2002. http://dx.doi.org/10.32747/2002.7586460.bard.

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Wild germplasm represents a rich source of QTLs capable of enhancing productivity of crop plants. Using the molecular linkage map of tomato in conjunction with novel population structures, we have identified QTLs from five Lycopersicon species that improve key yield and quality associated traits of processing tomatoes. In this research we employed multi-testing sites for fine mapping analysis of the different components of the affected traits combined with genetic interaction studies. Our results demonstrate that 'exotic libraries', which comprise of marker-defined genomic regions taken from wild species and introgressed onto the background of elite crop lines, provide an important opportunity for improving of the agricultural performance of modem crop varieties. Furthermore, we showed that these genetic resources can also serve as reagents for the discovery and characterization of genes that underlie traits of agricultural value. The results set the stage for using the QTLs in marker assisted programs and for applying map-based cloning of the targeted QTL/genes. The cloning of QTLs revealed genes that control pathways for agricultural yield in tomato that may be common for other crop species.
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Fahima, Tzion, and Jorge Dubcovsky. Map-based cloning of the novel stripe rust resistance gene YrG303 and its use to engineer 1B chromosome with multiple beneficial traits. United States Department of Agriculture, January 2013. http://dx.doi.org/10.32747/2013.7598147.bard.

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Research problem: Bread wheat (Triticumaestivum) provides approximately 20% of the calories and proteins consumed by humankind. As the world population continues to increase, it is necessary to improve wheat yields, increase grain quality, and minimize the losses produced by biotic and abiotic stresses. Stripe rust, caused by Pucciniastriiformisf. sp. tritici(Pst), is one of the most destructive diseases of wheat. The new pathogen races are more virulent and aggressive than previous ones and have produced large economic losses. A rich source for stripe-rust resistance genes (Yr) was found in wild emmer wheat populations from Israel. Original Project goals: Our long term goal is to identify, map, clone, characterize and deploy in breeding, novel wild emmer Yr genes, and combine them with multiple beneficial traits. The current study was aiming to map and clone YrG303 and Yr15, located on chromosome 1BS and combine them with drought resistance and grain quality genes. Positional cloning of YrG303/Yr15: Fine mapping of these genes revealed that YrG303 is actually allelic to Yr15. Fine genetic mapping using large segregating populations resulted in reduction of the genetic interval spanning Yr15 to less than 0.1 cM. Physical mapping of the YrG303/Yr15 locus was based on the complete chromosome 1BS physical map of wheat constructed by our group. Screening of 1BS BAC library with Yr15 markers revealed a long BAC scaffold covering the target region. The screening of T. dicoccoidesaccession-specific BAC library with Yr15 markers resulted in direct landing on the target site. Sequencing of T. dicoccoidesBAC clones that cover the YrG303/Yr15 locus revealed a single candidate gene (CG) with conserved domains that may indicate a role in disease resistance response. Validation of the CG was carried out using EMS mutagenesis (loss-of- function approach). Sequencing of the CG in susceptible yr15/yrG303 plants revealed three independent mutants that harbour non-functional yr15/yrG303 alleles within the CG conserved domains, and therefore validated its function as a Pstresistance gene. Evaluation of marker-assisted-selection (MAS) for Yr15. Introgressions of Yr15 into cultivated wheat are widely used now. Recently, we have shown that DNA markers linked to Yr15 can be used as efficient tools for introgression of Yr15 into cultivated wheat via MAS. The developed markers were consistent and polymorphic in all 34 tested introgressions and are the most recommended markers for the introgression of Yr15. These markers will facilitate simultaneous selection for multiple Yr genes and help to avoid escapees during the selection process. Engineering of improved chromosome 1BS that harbors multiple beneficial traits. We have implemented the knowledge and genetic resources accumulated in this project for the engineering of 1B "super-chromosome" that harbors multiple beneficial traits. We completed the generation of a chromosome including the rye 1RS distal segment associated with improved drought tolerance with the Yr gene, Yr15, and the strong gluten allele 7Bx-over-expressor (7Bxᴼᴱ). We have completed the introgression of this improved chromosome into our recently released variety Patwin-515HP and our rain fed variety Kern, as well as to our top breeding lines UC1767 and UC1745. Elucidating the mechanism of resistance exhibited by Yr36 (WKS1). The WHEAT KINASE START1 (WKS1) resistance gene (Yr36) confers partial resistance to Pst. We have shown that wheat plants transformed with WKS1 transcript are resistant to Pst. WKS1 is targeted to the chloroplast where it phosphorylates the thylakoid-associatedascorbateperoxidase (tAPX) and reduces its ability to detoxify peroxides. Based on these results, we propose that the phosphorylation of tAPX by WKS1 reduces the ability of the cells to detoxify ROS and contributes to cell death. Distribution and diversity of WKS in wild emmer populations. We have shown that WKS1 is present only in the southern distribution range of wild emmer in the Fertile Crescent. Sequence analysis revealed a high level of WKS1 conservation among wild emmer populations, in contrast to the high level of diversity observed in NB-LRR genes. This phenomenon shed some light on the evolution of genes that confer partial resistance to Pst. Three new WKS1 haplotypes displayed a resistance response, suggesting that they can be useful to improve wheat resistance to Pst. In summary, we have improved our understanding of cereals’ resistance mechanisms to rusts and we have used that knowledge to develop improved wheat varieties.
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Coyne, Karen M., Paul D. Gardner, and Aaron Scheid. Novel Particulate Air-Filtration Media: Market Survey. Fort Belvoir, VA: Defense Technical Information Center, February 2013. http://dx.doi.org/10.21236/ada602202.

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Bancroft, F. C. Novel Technology for Cloning Prostate Cancer Cell Markers. Fort Belvoir, VA: Defense Technical Information Center, February 2002. http://dx.doi.org/10.21236/ada405355.

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Esteva, Francisco J. Proteomic Analysis to Identify Novel Circulating Breast Cancer Markers. Fort Belvoir, VA: Defense Technical Information Center, June 2004. http://dx.doi.org/10.21236/ada426268.

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Esteva, Francisco J. Proteomic Analysis to Identify Novel Circulating Breast Cancer Markers. Fort Belvoir, VA: Defense Technical Information Center, June 2006. http://dx.doi.org/10.21236/ada467768.

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