Добірка наукової літератури з теми "NMR methodology"

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Статті в журналах з теми "NMR methodology":

1

CHAZIN, W. "NMR structures and methodology." Current Biology 2, no. 9 (September 1992): 510. http://dx.doi.org/10.1016/0960-9822(92)90693-5.

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2

Chazin, Walter J. "NMR structures and methodology." Current Opinion in Biotechnology 3, no. 4 (August 1992): 326–32. http://dx.doi.org/10.1016/0958-1669(92)90159-g.

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3

Bell, Nicholle G. A., Lorna Murray, Margaret C. Graham, and Dušan Uhrín. "NMR methodology for complex mixture ‘separation’." Chem. Commun. 50, no. 14 (2014): 1694–97. http://dx.doi.org/10.1039/c3cc48907h.

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4

McDevitt, Jayne C., Riju A. Gupta, Sydney G. Dickinson, Phillip L. Martin, Jean Rieuthavorn, Amy Freund, Marie C. Pizzorno, Elizabeth A. Capaldi, and David Rovnyak. "Methodology for Single Bee and Bee Brain 1H-NMR Metabolomics." Metabolites 11, no. 12 (December 13, 2021): 864. http://dx.doi.org/10.3390/metabo11120864.

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The feasibility of metabolomic 1H NMR spectroscopy is demonstrated for its potential to help unravel the complex factors that are impacting honeybee health and behavior. Targeted and non-targeted 1H NMR metabolic profiles of liquid and tissue samples of organisms could provide information on the pathology of infections and on environmentally induced stresses. This work reports on establishing extraction methods for NMR metabolic characterization of Apis mellifera, the European honeybee, describes the currently assignable aqueous metabolome, and gives examples of diverse samples (brain, head, body, whole bee) and biologically meaningful metabolic variation (drone, forager, day old, deformed wing virus). Both high-field (600 MHz) and low-field (80 MHz) methods are applicable, and 1H NMR can observe a useful subset of the metabolome of single bees using accessible NMR instrumentation (600 MHz, inverse room temperature probe) in order to avoid pooling several bees. Metabolite levels and changes can be measured by NMR in the bee brain, where dysregulation of metabolic processes has been implicated in colony collapse. For a targeted study, the ability to recover 10-hydroxy-2-decenoic acid in mandibular glands is shown, as well as markers of interest in the bee brain such as GABA (4-aminobutyrate), proline, and arginine. The findings here support the growing use of 1H NMR more broadly in bees, native pollinators, and insects.
5

Zı́dek, Lukáš, Richard Štefl, and Vladimı́ř Sklenář. "NMR methodology for the study of nucleic acids." Current Opinion in Structural Biology 11, no. 3 (June 2001): 275–81. http://dx.doi.org/10.1016/s0959-440x(00)00218-9.

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6

Sobolev, Anatoly, Donatella Capitani, Donato Giannino, Chiara Nicolodi, Giulio Testone, Flavio Santoro, Giovanna Frugis, et al. "NMR-Metabolic Methodology in the Study of GM Foods." Nutrients 2, no. 1 (January 13, 2010): 1–15. http://dx.doi.org/10.3390/nu2010001.

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7

Foston, Marcus B., Chistopher A. Hubbell, and Art J. Ragauskas. "Cellulose Isolation Methodology for NMR Analysis of Cellulose Ultrastructure." Materials 4, no. 11 (November 7, 2011): 1985–2002. http://dx.doi.org/10.3390/ma4111985.

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8

Sauers, Ronald R. "Cyclopropanes: Calculation of NMR spectra by ab initio methodology." Tetrahedron 54, no. 3-4 (January 1998): 337–48. http://dx.doi.org/10.1016/s0040-4020(97)10276-9.

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9

Pileio, Giuseppe. "Singlet NMR methodology in two-spin-1/2 systems." Progress in Nuclear Magnetic Resonance Spectroscopy 98-99 (February 2017): 1–19. http://dx.doi.org/10.1016/j.pnmrs.2016.11.002.

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10

Chalmers, Gordon R., Alexander Eletsky, Laura C. Morris, Jeong-Yeh Yang, Fang Tian, Robert J. Woods, Kelley W. Moremen, and James H. Prestegard. "NMR Resonance Assignment Methodology: Characterizing Large Sparsely Labeled Glycoproteins." Journal of Molecular Biology 431, no. 12 (May 2019): 2369–82. http://dx.doi.org/10.1016/j.jmb.2019.04.029.

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Дисертації з теми "NMR methodology":

1

Bayro, Marvin J. "Protein MAS NMR methodology and structural analysis of protein assemblies." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57800.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.
Vita. Cataloged from PDF version of thesis.
Includes bibliographical references.
Methodological developments and applications of solid-state magic-angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy, with particular emphasis on the analysis of protein structure, are described in this thesis. MAS NMR studies of biomolecules ranging from model peptides and proteins in crystalline form to amyloid fibrils and whole bacterial organelles are reported. The methods presented include novel pulse sequences and optimized pulse sequence elements, experimental approaches designed for multiple-spin systems, a protocol for efficient sequential resonance assignment of proteins in the solid state, and techniques to determine the inter-molecular organization of amyloid fibrils formed by moderately sized proteins. Notably, an efficient dipolar recoupling technique, bandselective radio frequency-driven recoupling (BASE RFDR), is introduced and combined with alternating 13C-12C labeling to yield highly sensitive 13C-13C correlation spectra between distant nuclei in proteins. Various applications of the BASE RFDR scheme are presented, including protein resonance assignment, determination of tertiary structure of amyloid fibrils, and variable-temperature studies of protein dynamics. The main biological systems analyzed are amyloid fibrils formed by the SH3 domain of P13 kinase (P13-SH3) and intact gas vesicles from anabaena flos-aquae, for which atomic-level structural information was previously unavailable. P13-SH3 (86 residues) is a system thoroughly studied as a model of protein misfolding and amyloid formation by a natively globular protein. Gas vesicles are bacterial buoyancy organelles, with walls composed almost entirely by a single protein (GvpA, 70 residues), whose formation and structure constitute a highly intriguing biophysical problem. Nearly complete 13C and 'IN resonance assignments and the molecular conformations of the polypeptide backbones of both P13-SH3 and GvpA have been obtained via MAS NMR spectroscopy, enabling the proposal of models for the structure of these two protein assembly systems. In addition, the tertiary structure of P13-SH3 amyloid fibrils has been elucidated by the application of novel methodology introduced in this thesis. Finally, investigations regarding the effects of temperature and protein dynamics on MAS NMR experiments and biomolecular dynamic nuclear polarization studies are presented.
by Marvin J. Bayro.
Ph.D.
2

Pöppler, Ann-Christin. "Advanced NMR Methodology for the Investigation of Organometallic Compounds in Solution." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://hdl.handle.net/11858/00-1735-0000-0001-BC26-5.

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3

Nambiath, chandran Jima. "Development of NMR methodology for the analysis and simplification of complex mixtures." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4306.

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Ces travaux de thèse portent sur l'analyse des mélanges réels et synthétiques complexes composés de petites molécules à l'aide de la RMN HRMAS. Dans une première partie, une approche RMN HRMAS basée sur l'analyse métabolomique en combinaison avec des techniques de reconnaissance des formes (PCA et O-PLS-DA) a été appliquée pour le diagnostic des lésions thyroïdiennes indéterminées et étudier également les effets biologiques négatifs des nanoparticules d'aluminium sur pseudomonas brassicacearum. Dans une seconde partie, nous avons étudié la RMN chromatographique en utilisant la silice comme matrice de support qui pourrait fournir une alternative rapide et complète de la LC pour la caractérisation de mélanges complexes. En outre, l'exigence de la suppression du signal dans l'extrait de plantes naturelles et d'hydrocarbures aromatiques conduit à l'élaboration d'une méthode rapide et précise en utilisant des polymères à empreintes moléculaires avec une excellente sélectivité. La sélectivité des polymères à empreintes moléculaires à travers la capture d'une cible moléculaire spécifique est exploitée ici pour éliminer efficacement les signaux RMN
This thesis work deals with the analysis of natural and synthetic complex mixtures composed of small molecules using HRMAS NMR. In a first part, an integrated HRMAS-NMR based metabolomic analysis in combination with pattern recognition techniques (PCA and O-PLS-DA) has been applied for the diagnosis of indeterminate thyroid lesions and also studied the potential adverse biological effects of aluminium nanoparticles on pseudomonas brassicacearum. In a second part we investigated that chromatographic NMR using silica as the matrix support could provide a quick alternative and complement to LC for the characterization of complex mixtures. In addition, requirement for signal suppression in natural plant extract and aromatic hydrocarbons led to the development of a rapid and accurate method using molecularly imprinted polymers with excellent selectivity. The selectivity of Molecularly Imprinted polymers towards capturing a specific molecular target is exploited here to efficiently remove NMR signals
4

Nambiath, chandran Jima. "Development of NMR methodology for the analysis and simplification of complex mixtures." Electronic Thesis or Diss., Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4306.

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Ces travaux de thèse portent sur l'analyse des mélanges réels et synthétiques complexes composés de petites molécules à l'aide de la RMN HRMAS. Dans une première partie, une approche RMN HRMAS basée sur l'analyse métabolomique en combinaison avec des techniques de reconnaissance des formes (PCA et O-PLS-DA) a été appliquée pour le diagnostic des lésions thyroïdiennes indéterminées et étudier également les effets biologiques négatifs des nanoparticules d'aluminium sur pseudomonas brassicacearum. Dans une seconde partie, nous avons étudié la RMN chromatographique en utilisant la silice comme matrice de support qui pourrait fournir une alternative rapide et complète de la LC pour la caractérisation de mélanges complexes. En outre, l'exigence de la suppression du signal dans l'extrait de plantes naturelles et d'hydrocarbures aromatiques conduit à l'élaboration d'une méthode rapide et précise en utilisant des polymères à empreintes moléculaires avec une excellente sélectivité. La sélectivité des polymères à empreintes moléculaires à travers la capture d'une cible moléculaire spécifique est exploitée ici pour éliminer efficacement les signaux RMN
This thesis work deals with the analysis of natural and synthetic complex mixtures composed of small molecules using HRMAS NMR. In a first part, an integrated HRMAS-NMR based metabolomic analysis in combination with pattern recognition techniques (PCA and O-PLS-DA) has been applied for the diagnosis of indeterminate thyroid lesions and also studied the potential adverse biological effects of aluminium nanoparticles on pseudomonas brassicacearum. In a second part we investigated that chromatographic NMR using silica as the matrix support could provide a quick alternative and complement to LC for the characterization of complex mixtures. In addition, requirement for signal suppression in natural plant extract and aromatic hydrocarbons led to the development of a rapid and accurate method using molecularly imprinted polymers with excellent selectivity. The selectivity of Molecularly Imprinted polymers towards capturing a specific molecular target is exploited here to efficiently remove NMR signals
5

Lewandowski, Józef Romuald. "Methodology and applications of high resolution solid-state NMR to structure determination of proteins." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45640.

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Анотація:
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Vita.
Includes bibliographical references.
A number of methodological developments and applications of solid-state NMR for assignment and high resolution structure determination of microcrystalline proteins and amyloid fibrils are presented. Magic angle spinning spectroscopy on uniformly and selectively "C and '5N labeled samples is performed at magnetic fields from 11.7 to 21.1 T and spinning frequencies from 9 to 65 kHz.Dynamic Nuclear Polarization on nanocrystals of amyloidogenic peptide GNNQQNY is presented demonstrating that 'H-'H spin diffusion can efficiently transfer the enhanced polarization across the solute that is not in an intimate contact with the polarizing agent.An improved theoretical treatment of Rotational Resonance Width (R2W) experiments and its application to determination of precise 13C-13C distance is presented. A general theory of second averaging in modulation frame for designing solid-state NMR experiments is introduced and discussed in the context of two methods: Cosine Modulated Rotary Resonance (CMpRR) for performing a broadband double-quantum 13C-13C recoupling without the need for additional 'H decoupling and Cosine Modulated recoupling with Chemical Shift reintroduction (COMICS) that provides a general frequency selective method for measuring precise 13C-13C distances in uniformly labeled solids. Cosine Modulated Adiabatic Recoupling (CMAR) - an adiabatic extension of the CMpRR, that is particularly robust with respect to rf inhomogeneity, is also introduced. A number of applications CMpRR at 21.1 T to proteins with varying degrees of macroscopic order are presented. A second order Third Spin Assisted Recoupling (TSAR) mechanism is introduced and discussed in detail. The heteronuclear TSAR - Proton Assisted Insensitive Nuclei Cross-Polarization (PAIN-CP) and homonuclear Proton Assisted Recoupling (PAR) yield long distance 13C_1-N, 3C-_13C and 15N- 5N restraints in uniformly labeled systems with spinning frequencies up to 65 kHz that are used for protein structure calculation. Structure, dynamics and polymorphism of amyloidogenic peptide GNNQQNY from the yeast protein sup35p are investigated. Finally, PAIN-CP and '3C-13C PAR are used for high resolution de novo structure determination of 10.4 kDa Crh protein dimer.
by Józef Romuald Lewandowski.
Ph.D.
6

Kleks, Guy. "Development of NMR Methodology for Complex Mixture Analysis and Discovery of Antiplasmodial Marine Natural Products." Thesis, Griffith University, 2021. http://hdl.handle.net/10072/401350.

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One of the challenges in natural product discovery is the re-isolation and identification of known compounds. Dereplication is the process of identifying known compounds, allowing time and effort involved in their isolation and structure elucidation to be saved, thus enabling focus to be directed solely on new compounds. While dereplication is mainly MS-based, the main tool for structure elucidation of natural products is NMR. These techniques are very different to each other, with the only current approach in which they can be correlated is by hyphenated techniques such as LC-NMR-MS, requiring specialist and expensive hardware that is not available in every lab. In this thesis we develop structure and molecular size based NMR methodology for analysis of complex mixtures, such as those encountered in natural product research. We have used Diffusion Ordered Spectroscopy (DOSY), an NMR technique that enables components of a mixture to be distinguished by their diffusion coefficients (D), corresponding to hydrodynamic size. Since DOSY has mostly been used for organometallic and polymer analysis, we have established a calibration curve consisting mostly of natural products that provides a correlation between D to molecular weight (MW), allowing MW prediction from experimental D. Since physicochemical properties such as hydrogen bonding, molar density and molecular shape have been shown to affect D and therefore MW prediction, we have generated two new MW prediction models. The first model takes hydrogen bonding into account by the chemical shift of the most acidic hydrogen bond donor (HBD), and the second model provides a more accurate MW prediction for RP HPLC fractions based on the percentage MeOH the compound elutes it. We have generated predicted D based on structural and chemical properties for a database of 220,817 natural products, allowing dereplication by use of a D filter based on the experimental D in conjunction with structural filters based on NMR data. These models have been validated by the dereplication of a mixture of two sesquiterpenes from the plant Tasmannia xerophila, and the dereplication of three known tropane alkaloids in a complex mixture from Darlingia ferruginea. 3D DOSY methodology was undertaken for the analysis of the D. ferruginea complex mixture, allowing molecular fragments to be constructed from DOSY-COSY data. We have also projected diffusion data derived from DOSY-HSQC data onto an HMBC spectrum to generate complex fragments containing non protonated carbons, and this has provided a powerful tool for dereplication. These molecular fragments allowed dereplication and the annotation of three new tropane alkaloids in a complex mixture. These new compounds, together with other known alkaloids were subsequently isolated, and extensive 2D NMR and ECD data allowed their total absolute structures to be assigned to the three new compounds and the structure revision of two of the known compounds, one previously reported as it is diastereomer and both originally wrongly assigned as their opposite enantiomers. In this thesis we report the chemical investigation of two bryozoan species, members of a marine invertebrate phylum that is one of the most understudied. These species were selected for investigation after their extracts were identified as possessing potent bioactivity during an antiplasmodial screening of 486 marine invertebrate crude extracts collected in Australia as active toward the Plasmodium falciparum parasite, the causative agent of the malaria disease. The bryozoan Orthoscuticella ventricosa has afforded five new β-carboline alkaloids, two of which contained were bis-β-carboline containing an uncommon 1,2-disubstituted cyclobutane moiety. These compounds displayed weak antiplasmodial activity against the chloroquine-sensitive strain (3D7) of the P. falciparum. The bryozoan Amathia lamourouxi has afforded six new brominated alkaloids. Two of these displayed sub-micromolar antiplasmodial activity against both chloroquine-sensitive (3D7) and chloroquine-resistant (Dd2) P. falciparum strains and good selectivity relative to the human cell line, marking these compounds as validated antimalarial hits.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Environment and Sc
Science, Environment, Engineering and Technology
Full Text
7

Linser, Rasmus Jan. "Development and application of new methodology for 1 H-detected MAS solid-state NMR on biomolecules." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2010. http://dx.doi.org/10.18452/16199.

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In der hier vorgestellten Arbeit werden neuartige Festkörper-NMR (Nuclear Magnetic Resonance) Experimente vorgestellt, die eine direkte Detektion von Protonen einbeziehen. Die Technik basiert auf einer weitgehenden Verdünnung der Protonen durch Deuteronen in vollständig isotopenmarkierten, rekombinant exprimierten Proteinen und ermöglicht Festkörper-NMR mit sehr schmalen Linienbreiten aller standardmäßig erfassbaren Kerne (Protonen, Stickstoff, Kohlenstoff) ohne Hochleistungsentkopplung. Zusätzlich werden Methoden für ein besonders hohes Signal-zu-Rausch durch Paramagnetic Relaxation Enhancement (PRE) entwickelt. Die so präparierten Proteine erweisen sich tauglich für eine stark verbesserte NMR-Charakterisierung durch eine Vielzahl neuer Struktur- und Zuordnungsexperimente, in denen Techniken aus Festkörper- und Lösungs-NMR vereint werden. Dabei können hier erstmals auch Bereiche im Protein mit einbezogen werden, die langsame Dynamik vollziehen. Die Experimente finden Anwendung auf die SH3-Domäne von alpha-Spektrin, das Alzheimer-Peptid Abeta1-40 und das Membranprotein Omp G.
In this work, novel solid-state NMR (Nuclear Magnetic Resonance) experiments are presented that imply direct detection of protons. The technique is based on extensive dilution of protons with deuterons in uniformly labelled, recombinantly expressed proteins and allows for solid-state NMR providing very narrow lines of all commonly accessible nuclei (protons, nitrogen, carbon) without high-power decoupling. In addition, methods are developed that yield a particularly high signal-to-noise through Paramagnetic Relaxation Enhancement (PRE). The accordingly prepared proteins are shown to be applicable for a significantly improved NMR-characterization by manifold new experiments for assignment and structure elucidation, in which techniques from solid-state and solution NMR are united. For the first time, also those regions in a protein can be accessed that undergo slow dynamics. The experiments are employed on the SH3-domain of alpha-spectrin, Alzheimer’s peptide Abeta1‑40, and the membrane protein Omp G.
8

Myers, Emma Paige. "Solid State ²H NMR Spectroscopy Analysis of Lipid-Protein Interactions in Response to Bilayer Deformations: Development of Methodology." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/297723.

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Using solid-state 2H NMR spectroscopy, one can obtain de-convoluted NMR spectra which can then be used to evaluate segmental order parameters. These order parameters describe the motional averaging of C - ²H segments with respect to the bilayer normal, and are therefore related to bilayer structural parameters such as the mean area per lipid and the volumetric bilayer thickness. From this type of data, the effect of various stresses (hydration pressure, osmotic stress) on the lipid bilayer can be quantified. This type of analysis has been made with DMPC-d₅₄ as the lipid sample and polyethylene glycol (PEG) of molecular weight 1500 (PEG 1500) as the osmolyte. We plan to extend this work with other lipid systems like POPC and osmolytes such as PEG 8000 in order to provide more varied data in terms of sample identity. The long-term goal is to provide enough experimental data on various lipid samples to be able to make a qualitative analysis on how bilayer deformation influences non-specific lipid-protein interactions. This paper develops the methodology for the data reduction and analysis procedures used in our analysis of these lipid samples, while demonstrating the applicability of solid-state ²H NMR spectroscopy in investigating structural properties of lipid bilayers.
9

Grohe, Kristof [Verfasser], and Rasmus [Akademischer Betreuer] Linser. "Development and application of novel NMR methodology for elucidation of protein structure and dynamics / Kristof Grohe ; Betreuer: Rasmus Linser." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/122384983X/34.

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10

Pöppler, Ann-Christin [Verfasser], Dietmar [Akademischer Betreuer] Stalke, and Philipp [Akademischer Betreuer] Vana. "Advanced NMR Methodology for the Investigation of Organometallic Compounds in Solution / Ann-Christin Pöppler. Gutachter: Dietmar Stalke ; Philipp Vana. Betreuer: Dietmar Stalke." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044870362/34.

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Книги з теми "NMR methodology":

1

Heise, Henrike, and Stephen Matthews, eds. Modern NMR Methodology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-37991-8.

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2

Kimmich, R. NMR: Tomography, diffusometry, relaxometry. Berlin: Springer, 1997.

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3

G, Shulman R., and Rothman D. L, eds. Metabolomics by in vivo NMR. Chichester, West Sussex: John Wiley & Sons, 2005.

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4

Bertini, Ivano. NMR of paramagnetic molecules in biological systems. Menlo Park, Calif: Benjamin/Cummings Pub. Co., 1986.

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5

D, Osbakken Mary, and Haselgrove John, eds. NMR techniques in the study of cardiovascular structure and function. Mount Kisco, N.Y: Futura Pub. Co., 1988.

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6

David, Live, Armitage Ian M, Patel Dinshaw, Abbott Laboratories, University of California, Los Angeles., and UCLA Colloquium, Frontiers of NMR in Molecular Biology (1989 : Park City, Utah), eds. Frontiersof NMR in molecular biology: Proceedings of an Abbott Laboratories--UCLA symposia colloquium held at Park City, Utah, January 12-19, 1989. New York: Wiley-Liss, 1990.

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7

Stephen, Davies. NME 2: Multinationals in UK manufacturing : research design : data collection methodology. Norwich: School of Economic and Social Studies, University of East Anglia, 1985.

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8

Matthews, Stephen, and Henrike Heise. Modern NMR Methodology. Springer London, Limited, 2014.

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9

Matthews, Stephen, and Henrike Heise. Modern NMR Methodology. Springer, 2015.

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10

Modern Nmr Methodology. Springer-Verlag Berlin and Heidelberg GmbH &, 2013.

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Частини книг з теми "NMR methodology":

1

Duddeck, Helmut, Wolfgang Dietrich, and Gábor Tóth. "Methodology." In Structure Elucidation by Modern NMR, 7–43. Heidelberg: Steinkopff, 1998. http://dx.doi.org/10.1007/978-3-642-88310-1_2.

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2

Duddeck, H., and W. Dietrich. "Methodology." In Structure Elucidation by Modern NMR, 5–28. Heidelberg: Steinkopff, 1989. http://dx.doi.org/10.1007/978-3-642-97781-7_2.

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3

Duddeck, Helmut, and Wolfgang Dietrich. "Methodology." In Structure Elucidation by Modern NMR, 7–30. Heidelberg: Steinkopff, 1992. http://dx.doi.org/10.1007/978-3-642-97787-9_2.

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4

Mehta, Mitul A. "Noninvasive Methodology (NMR)." In Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 1–15. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-56637-5_46-1.

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5

Mehta, Mitul A. "Noninvasive Methodology (NMR)." In Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 439–53. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-68864-0_46.

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La Mar, Gerd N., and Jeffrey S. de Ropp. "NMR Methodology for Paramagnetic Proteins." In NMR of Paramagnetic Molecules, 1–78. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2886-9_1.

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7

Franks, W. Trent, Barth-Jan van Rossum, Benjamin Bardiaux, Enrico Ravera, Giacomo Parigi, Claudio Luchinat, and Hartmut Oschkinat. "Microcrystalline Proteins - An Ideal Benchmark for Methodology Development." In NMR of Biomolecules, 376–92. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch22.

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8

Tang, Mingxue, Riqiang Fu, Michaël Deschamps, K. Romanenko, and A. Jerschow. "CHAPTER 2. The Methodology of Electrochemical In Situ NMR and MRI." In New Developments in NMR, 71–105. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839160097-00071.

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9

Gerothanassis, Ioannis P., Vassiliki Exarchou, Anastasios Troganis, Maria Tsimidou, and Dimitrios Boskou. "NMR methodology for the analysis of phenolic acids in complex phenolic mixtures." In Spectroscopy of Biological Molecules: New Directions, 585–86. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4479-7_262.

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10

Gerothanassis, I. P., P. J. Barrie, M. Momenteau, and G. E. Hawkes. "13C NMR Studies of Hemoproteins and Model Compounds in the Solid: Methodology and Applications." In Spectroscopy of Biological Molecules, 241–42. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0371-8_108.

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Тези доповідей конференцій з теми "NMR methodology":

1

Singer, Gabriela, Mark Flaum, Songhua Chen, and S. Mark Ma. "NMR DRILL CUTTING ANALYSIS: METHODOLOGY EVALUATION AND OPERATIONAL BEST PRACTICES." In 2021 SPWLA 62nd Annual Logging Symposium Online. Society of Petrophysicists and Well Log Analysts, 2021. http://dx.doi.org/10.30632/spwla-2021-0095.

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Drill cuttings are available in every well drilled and NMR is a powerful tool for characterization of rocks and fluids. It is thus desirable if useful petrophysical information can be derived from NMR drill cutting analysis. However, previous studies have shown that there are many uncertainties associated with cutting analysis by using NMR, such as (1) the small cutting size may not be representative of the formation rock pore system, and (2) the effect of drilling fluids which may penetrate and clog the pore space may result in uncertain pore typing and pore surface characterization. In this paper, based on a detailed methodology evaluation study using cuttings with different rock types, cutting sizes, and with different mud contaminations, we present experimental evidence to show (1) the best operational practices to remove mud and excess fluid contamination, and (2) the minimal cutting size required to obtain useful petrophysical information. In addition, we will also provide recommended cuttings preparation procedures and set the practical expectations for NMR drilling cutting analysis.
2

Steiner, S., and W. Looyestijn. "New Methodology for NMR Interpretation in Lower Cretaceous Chalk Reservoirs." In 74th EAGE Conference and Exhibition incorporating EUROPEC 2012. Netherlands: EAGE Publications BV, 2012. http://dx.doi.org/10.3997/2214-4609.20148557.

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3

Breda, Eduardo, Anibal Silveira, Juan Homovc, and Carlos Minetto. "Quick Look Methodology for Gas Detection Using NMR and Density Porosity." In SPE Asia Pacific Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 2000. http://dx.doi.org/10.2118/64515-ms.

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4

Pogorevc, Rok, Tina Ročnik, Blaž Likozar, Edita Jasiukaitytė-Grojzdek, and Miha Grilc. "Development of FT–IR, UV and Fluorescence Based Analytical Methodology for Lignin Characterisation." In International Conference on Technologies & Business Models for Circular Economy. University of Maribor Press, 2022. http://dx.doi.org/10.18690/um.fkkt.3.2022.3.

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The development of the novel analytical methodologies for lignin chracterisation is presented. Lignin fractions were characterized by NMR, SEC/GPC as well new analytical methodologies were implemented such as FT–IR, UV and fluorescence. FT–IR and fluorescence results show a promising correlation to the NMR and SEC/GPC analysis. Main findings from the SEC/GPC and NMR results indicates that by adding more water to the organosolv spent liquor isolated lignin contains lower amount of β-O 4 linking motif and also has a lower molecular weight. The following is also confirmed by the straightforward analysis using FT–IR and fluorescence giving the opportunity to replace time-consuming and complex lignin characterisation methods with a simple and quick analytics and the possibility to be applied for the in-process control in continuous production processes.
5

Asahina, K., and T. Nemoto. "NMR-Petro analysis; A novel methodology for molecular indicators using statistical pattern recognition." In 29th International Meeting on Organic Geochemistry. European Association of Geoscientists & Engineers, 2019. http://dx.doi.org/10.3997/2214-4609.201902942.

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6

Morawitz, Falk. "Multilayered Narration in Electroacoustic Music Composition Using Nuclear Magnetic Resonance Data Sonification and Acousmatic Storytelling." In ICAD 2019: The 25th International Conference on Auditory Display. Newcastle upon Tyne, United Kingdom: Department of Computer and Information Sciences, Northumbria University, 2019. http://dx.doi.org/10.21785/icad2019.052.

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Nuclear magnetic resonance (NMR) spectroscopy is an analytical tool to determine the structure of chemical compounds. Unlike other spectroscopic methods, signals recorded using NMR spectrometers are frequently in a range of zero to 20000 Hz, making direct playback possible. As each type of molecule has, based on its structural features, distinct and predictable features in its NMR spectra, NMR data sonification can be used to create auditory ‘fingerprints’ of molecules. This paper describes the methodology of NMR data sonification of the nuclei nitrogen, phosphorous, and oxygen and analyses the sonification products of DNA and protein NMR data. The paper introduces On the Extinction of a Species, an acousmatic music composition combining NMR data sonification and voice narration. Ideas developed in electroacoustic composition, such as acousmatic storytelling and sound-based narration are presented and investigated for their use in sonification-based creative works.
7

Sharma, Sharanya, Craig Duhe, and Bo Gao. "Evaluation of NMR Derived Capillary Pressure Curves Against Porous Plate Data for a Sandstone Reservoir." In SPE Reservoir Characterisation and Simulation Conference and Exhibition. SPE, 2023. http://dx.doi.org/10.2118/212604-ms.

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Abstract NMR assisted capillary pressure and water saturation measurements have proven to be significantly faster than traditional porous plate and centrifuge methods. The NMR directly measures water saturation along the length of the core and associated capillary pressure generated at a given centrifuge speed. It overcomes limitations of requiring lengthy equilibration times, tedious material balance, and approximate solutions. However, limited data is available with respect to actual application and operating range of the technology in reservoir cores. The objective of this study is to evaluate data quality, identify best practices, and any limitations in utilizing the faster NMR derived capillary pressure curves when compared against the gold standard porous plate method. Core samples from a sandstone reservoir were selected to test a permeability range between 400mD – 1600mD. Representative synthetic reservoir brine was used in the tests. All plugs selected for the NMR capillary pressure study had associated porous plate data available. NMR capillary pressure curve was generated using the GIT-CAP patented methodology for three, four, and eight centrifuge speeds to understand the impact of test speed on capillary pressure curve resolution. The tests were performed at net confining stress and at ambient conditions to evaluate if large differences were observed in results. Gravimetric measurements were simultaneously obtained to ensure data quality. Two different available imaging pulse sequences – SE-SPI and the SPRITE method were also evaluated for the different samples in generating the NMR assisted capillary pressure curves. This work contributes to outlining parameters for workflow optimization when adopting this methodology in real field applications.
8

Chohan, Mohammad Azeem, Rex Sy, Stephanie Perry, and Christopher Savage. "Integrated Petrophysical Evaluation of Unconventional Formations, in the Delaware Basin, With a Customized NMR Acquisition." In 2022 SPWLA 63rd Annual Symposium. Society of Petrophysicists and Well Log Analysts, 2022. http://dx.doi.org/10.30632/spwla-2022-0085.

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Unconventional shale reservoirs have complex lithology, porosity and fluid systems where hydrocarbons are stored in both inter- and intra-particle pores. Hence, conventional log measurements and petrophysical techniques often fail to provide a consistent analysis for key petrophysical properties such as porosity and hydrocarbon saturation. Nuclear magnetic resonance (NMR) logging has gained an importance in unconventional resource evaluation, for its promise to allow in-situ differentiation of various fluid phases and their potential to flow. However, in unconventional reservoirs, pore sizes may range from only a few nanometers to a few hundred micrometers: in these small pores the NMR signal relaxes rapidly, making it challenging to measure using standard NMR acquisition modes and methodologies. This paper introduces a custom NMR log acquisition mode that is designed to measure these fast-relaxing components, to improve porosity identification and fluid typing in unconventional shale reservoirs. This is implemented through both tool improvements and novel processing techniques in the T2 and T1-T2 logging modes. Furthermore, the methodology can optionally incorporate other conventional and advanced measurements (such as, elemental spectroscopy, and multi frequency dielectric) as part of an integrated system to further constrain and compute key petrophysical properties. The methodology was applied to the Bone Spring and Wolfcamp formations of the Delaware Basin, integrating the NMR data with open hole log data, including density, porosity, and total organic content from elemental spectroscopy logs to identify organic rich zones. Integration of multifrequency dielectric measurements further increases confidence in estimating water filled porosity and hydrocarbon saturation within the reservoir. This methodology results in improved quantification of key reservoir properties such as porosity and hydrocarbon saturation. Compared to existing methodologies, benefits include increased logging speed, therefore saving rig time, improved hydrocarbon typing and quantification, and the ability to integrate with laboratory-based measurements, advanced logging suites and cuttings analysis to better identify and quantify productive zones. We present a case study applying the new NMR acquisition mode and demonstrating the improvements in quantification of the reservoir properties.
9

Kelly, Shaina, Ron J. M. Bonnie, Micheal J. Dick, and Dragan Veselinovic. "NMR WETTABILITY INDEX MEASUREMENTS AND METHODS COMPARED ON A VARIETY OF UNCONVENTIONAL SAMPLES." In 2021 SPWLA 62nd Annual Logging Symposium Online. Society of Petrophysicists and Well Log Analysts, 2021. http://dx.doi.org/10.30632/spwla-2021-0096.

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Matrix wettability is a key driver in relative permeability and, hence, a critical factor controlling imbibition and drainage at UR fracture-matrix interfaces as well as enhanced oil recovery (EOR). In this study, we (1) adapt and apply the NMR-based wettability index (NWI) methodology of Looyestijn et al. (2006) to a variety of unconventional twin samples undergoing, respectively, spontaneous imbibition with oil-displacing-water and water-displacing-oil and (2) compare the robustness of this method among a variety of samples pairs and also to other NMR-based wettability methods. The samples analyzed cover a range of rock types, major formations, maturity and content of organic material. All displayed unique time-lapse wettability profiles and steady state NWI values. This work advances our previous works (Dick et al., 2019; Kelly et al., 2020) on this subject, where the viability of the methodology was established on end-member pilot samples, towards applicability as a UR SCAL method. The NWI methodology predicts T2 spectra using linear combinations (mixing) of “end-point” T2 spectra. The mixing ratios yielding the closest match to the measured spectra are then used to compute a wettability index. These mixing ratios were validated against (1) mass-balance calculations, (2) repeat experiments with heavy water (D2O) instead of H2O and (3) measured T1-T2 maps, enhancing confidence in the robustness of the method. Our comparisons show that alternative approaches representing the T2 spectra through a single mean T2 value or T2 peak-fit, fall short, especially in tight rocks where fast relaxation rate components tend to skew harmonic mean T2 values and also in samples where oil and water peaks are not clearly resolved. Full spectrum-based methods, akin to Looyestijn’s, appear more robust and stable over a much wider range of reservoir conditions. Repeated NMR acquisition throughout our long-term imbibition experiments shows that time-lapse NWI methodology probes the effects of rock properties, saturation changes, and injected fluid chemistry (enhanced oil recovery strategies) on wettability alteration. Additionally, this NWI study quantifies the wide variation in wettability among unconventional samples.
10

Kayode, B., F. Al-Tarrah, and G. Hursan. "Methodology for Static and Dynamic Modeling of Hydrocarbon Systems Having Sharp Viscosity Gradient." In International Petroleum Technology Conference. IPTC, 2021. http://dx.doi.org/10.2523/iptc-21184-ms.

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Abstract This paper describes a methodology for delineating tar surface, incorporating it into a geological model, and the process for numerical modeling of oil viscosity variation with depth above the tar surface. The methodology integrates well log data and compositional fluid analysis to develop a mathematical model that mimics the oil's property variation with depth. While there are a good number of reservoirs that fit this description globally, there is a knowledge gap in literature regarding best practices for dealing with the peculiar challenges of such reservoirs. These challenges include; (i) how to delineate the top-of-tar across the field, (ii) modeling of Saturation Height Function (SHF) in a system where density and wettability is changing with depth, and (iii) the methodology for representing the depth-dependent oil properties (especially viscosity) in reservoir simulation. Nuclear magnetic resonance (NMR) logs were used to predict fluid viscosity using a technique discussed by Hursan et al. (2016). Viscosity regions are identified at every well that has an NMR log, and these regions are mapped from well to well across the reservoir. Within each viscosity region, the analysis results of fluid samples collected from wells are used to develop mathematical models of fluid composition variation with depth. A reliable SHF model was achieved by incorporating depth-varying oil density and depth varying wettability into the calculation of J-Function. A compositional reservoir simulation was set-up, using the viscosity regions and the mathematical models describing composition variation with depth, for the respective regions. Using information obtained from literature as a starting point, residual oil saturation was modeled as a function of oil viscosity. Original reservoir understanding places the top of non-movable oil (tar) at a constant fieldwide subsurface depth, which corresponds to the shallowest historical no-flow drillstem test (DST) depth. Mapping of the NMR viscosity regions across the field resulted in a sloping tar-oil contact (TOC), which resulted in an increase of movable hydrocarbon pore volume. The viscosity versus depth profile from the simulation model matched the observed data, and allow the simulation model better predict well performance. In addition, the simulation model results also matched the depth-variation of observed formation volume factor (FVF) and reservoir fluid density. Some wells that have measured viscosity data but no NMR logs were used as blind-test wells. The simulation model results also matched the measured viscosity at those blind-test wells. These good matches of the oil property variation with depth gave confidence, that the simulation model could be used as an efficient planning tool for ensuring that injectors are placed just-above the tar mat. The use of the simulation model for well planning could reduce the need for geosteering while drilling flank wells, leading to savings in financial costs. This paper contains a generalized approach that can be used in static and dynamic modeling of reservoirs, where oil changes from light to medium to heavy oil, underlain by tar. It contains recommendations and guidelines to construct a reliable simulation model of such systems.

Звіти організацій з теми "NMR methodology":

1

Mir, Ali, Saleem Shaikh, Mumraiz Khan, Irfan Masood, Mansoor Qaisar, Sabahat Hussain, and Rehan Niazi. Using the community informant-based (MADE-IN and MADE-FOR) methodology to estimate the neonatal mortality rate (NMR) in Nowshera, Khyber Pakhtunkhwa: A feasibility study. Population Council, 2016. http://dx.doi.org/10.31899/rh8.1085.

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2

Binette, Joanne. AARP 2017 Age-Friendly Community Survey: Bernalillo County, NM: Methodology Report. AARP Research, December 2017. http://dx.doi.org/10.26419/res.00055.054.

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3

Ramos, Nuno M. M., Joana Maia, Rita Carvalho Veloso, Andrea Resende Souza, Catarina Dias, and João Ventura. Envelope systems with high solar reflectance by the inclusion of nanoparticles – an overview of the EnReflect Project. Department of the Built Environment, 2023. http://dx.doi.org/10.54337/aau541621982.

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High reflectance materials constitute an attractive idea to reduce cooling loads, which is crucial for attaining the Nearly Zero Energy Buildings goal, also presenting the benefit of broadening the range of colours applicable in building facades. The EnReflect project intended to re-design envelope systems by increasing their solar reflectance through nanotechnology. The main idea was to produce novel nanomaterial-based coatings with high near-infrared (NIR) reflectance by tuning their optical properties and testing their compatibility with typical insulation technologies such as ETICS. As such, this project focused on the synthesis of nanoparticles with improved NIR reflectance, the evaluation of the hygrothermal-mechanical behaviour of thermal insulation systems with the application of the improved coating solutions, the characterization of the more relevant material properties and the durability assessment. One of the main achievements was the development of a facile synthesis of a nanocomposite with improved performance in the NIR region that allowed the reflectance improvement of a dark-finishing coating. Also, the incorporation of such nanoparticles had a positive effect on keeping their optical properties after accelerated ageing cycles. The development of numerical simulations allowed the estimation of the maximum surface temperature in Mediterranean climates under different optical parameters. The study of the hygrothermal behaviour of thermal enhanced façades led to the development of a new durability assessment methodology which contributed to closing a standardization gap.
4

Leis and Zhu. PR-003-063526-R01 Leak vs Rupture Boundary for Pipes with a Focus on Low Toughness and-or Ductility. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), April 2012. http://dx.doi.org/10.55274/r0010781.

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While the technology to manage corrosion is largely mature, just one high-profile corrosion incident, like that at Carlsbad, NM, rekindles the public�s concern for safety, with far reaching effects possibly into Congress and the regulatory management. Such incidents also bring into question the viability of related integrity management tools and practices � particularly those used to assess incident consequences and prioritize related maintenance. Reliably discriminating between leaks and ruptures thus is important � but remains elusive for many applications. This project sought new understanding and a methodology to determine the leak versus rupture (L vs R) boundary for pipe-body corrosion. The first phase of this project formulated this new methodology and evaluated it in regards to factors such as defect acuity, constraint, loading mode (hydrostatic versus pneumatic), and material toughness and ductility. Because of concern in regard to its use for higher-strength grades, possible limitations due to grade were evaluated relative to the literature and full-scale data in the second phase of the project.
5

Kalkar, Uma, and Natalia González Alarcón. Facilitating Data Flows through Data Collaboratives: A Practical Guide to Designing Valuable, Accessible, and Responsible Data Collaboratives. Inter-American Development Bank, October 2023. http://dx.doi.org/10.18235/0005185.

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Data is an indispensable asset in today's society, but its production and sharing are subject to well-known market failures. Among these: neither economic nor academic markets efficiently reward costly data collection and quality assurance efforts; data providers cannot easily supervise the appropriate use of their data; and, correspondingly, users have weak incentives to pay for, acknowledge, and protect data that they receive from providers. Data collaboratives are a potential non-market solution to this problem, bringing together data providers and users to address these market failures. The governance frameworks for these collaboratives are varied and complex and their details are not widely known. This guide proposes a methodology and a set of common elements that facilitate experimentation and creation of collaborative environments. It offers guidance to governments on implementing effective data collaboratives as a means to promote data flows in Latin America and the Caribbean, harnessing their potential to design more effective services and improve public policies.
6

Weinschenk, Craig, Daniel Madrzykowski, and Paul Courtney. Impact of Flashover Fire Conditions on Exposed Energized Electrical Cords and Cables. UL Firefighter Safety Research Institute, October 2019. http://dx.doi.org/10.54206/102376/hdmn5904.

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A set of experiments was conducted to expose different types of energized electrical cords for lamps, office equipment, and appliances to a developing room fire exposure. All of the cords were positioned on the floor and arranged in a manner to receive a similar thermal exposure. Six types of cords commonly used as power supply cords, extension cords, and as part of residential electrical wiring systems were chosen for the experiments. The non-metallic sheathed cables (NMB) typically found in residential electrical branch wiring were included to provide a link to previous research. The basic test design was to expose the six different types of cords, on the floor of a compartment to a growing fire to determine the conditions under which the cord would trip the circuit breaker and/or undergo an arc fault. All of the cords would be energized and installed on a non-combustible surface. Six cord types (18-2 SPT1, 16-3 SJTW, 12-2 NM-B, 12-3 NM-B, 18-3 SVT, 18-2 NISPT-2) and three types of circuit protection (Molded case circuit breaker (MCCB), combination Arc-fault circuit interrupter (AFCI), Ground-fault circuit interrupter (GFCI)) were exposed to six room-scale fires. The circuit protection was remote from the thermal exposure. The six room fires consisted of three replicate fires with two sofas as the main fuel source, two replicate fires with one sofa as the main fuel source and one fire with two sofas and MDF paneling on three walls in the room. Each fuel package was sufficient to support flashover conditions in the room and as a result, the impact on the cords and circuit protection was not significantly different. The average peak heat release rate of the sofa fueled compartment fires with gypsum board ceiling and walls was 6.8 MW. The addition of vinyl covered MDF wall paneling on three of the compartment walls increased the peak heat release rate to 12 MW, although most of the increased energy release occurred outside of the compartment opening. In each experiment during post flashover exposure, the insulation on the cords ignited and burned through, exposing bare conductor. During this period the circuits faulted. The circuit protection devices are not designed to provide thermal protection, and, thus, were installed remote from the fire. The devices operated as designed in all experiments. All of the circuit faults resulted in either a magnetic trip of the conventional circuit breaker or a ground-fault trip in the GFCI or AFCI capable circuit protection devices. Though not required by UL 1699, Standard for Safety for Arc-Fault Circuit-Interrupters as the solution for detection methodology, the AFCIs used had differential current detection. Examination of signal data showed that the only cord types that tripped with a fault to ground were the insulated conductors in non-metallic sheathed cables (12-2 NM-B and 12-3 NM-B). This was expected due to the bare grounding conductor present. Assessments of both the thermal exposure and physical damage to the cords did not reveal any correlation between the thermal exposure, cord damage, and trip type.
7

Visser, R., H. Kao, R. M. H. Dokht, A. B. Mahani, and S. Venables. A comprehensive earthquake catalogue for northeastern British Columbia: the northern Montney trend from 2017 to 2020 and the Kiskatinaw Seismic Monitoring and Mitigation Area from 2019 to 2020. Natural Resources Canada/CMSS/Information Management, 2021. http://dx.doi.org/10.4095/329078.

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To increase our understanding of induced seismicity, we develop and implement methods to enhance seismic monitoring capabilities in northeastern British Columbia (NE BC). We deploy two different machine learning models to identify earthquake phases using waveform data from regional seismic stations and utilize an earthquake database management system to streamline the construction and maintenance of an up-to-date earthquake catalogue. The completion of this study allows for a comprehensive catalogue in NE BC from 2014 to 2020 by building upon our previous 2014-2016 and 2017-2018 catalogues. The bounds of the area where earthquakes were located were between 55.5°N-60.0°N and 119.8°W-123.5°W. The earthquakes in the catalogue were initially detected by machine learning models, then reviewed by an analyst to confirm correct identification, and finally located using the Non-Linear Location (NonLinLoc) algorithm. Two distinct sub-areas within the bounds consider different periods to supplement what was not covered in previously published reports - the Northern Montney Trend (NMT) is covered from 2017 to 2020 while the Kiskatinaw Seismic Monitoring and Mitigation Area (KSMMA) is covered from 2019 to 2020. The two sub-areas are distinguished by the BC Oil & Gas Commission (BCOGC) due to differences in their geographic location and geology. The catalogue was produced by picking arrival phases on continuous seismic waveforms from 51 stations operated by various organizations in the region. A total of 17,908 events passed our quality control criteria and are included in the final catalogue. Comparably, the routine Canadian National Seismograph Network (CNSN) catalogue reports 207 seismic events - all events in the CNSN catalogue are present in our catalogue. Our catalogue benefits from the use of enhanced station coverage and improved methodology. The total number of events in our catalogue in 2017, 2018, 2019, and 2020 were 62, 47, 9579 and 8220, respectively. The first two years correspond to seismicity in the NMT where poor station coverage makes it difficult to detect small magnitude events. The magnitude of completeness within the KSMMA (ML = ~0.7) is significantly smaller than that obtained for the NMT (ML = ~1.4). The new catalogue is released with separate files for origins, arrivals, and magnitudes which can be joined using the unique ID assigned to each event.
8

Abbate, Nicolás, Inés Berniell, Joaquín Coleff, Luis Laguinge, Margarita Machelett, Mariana Marchionni, Julián Pedrazzi, and María Florencia Pinto. Discrimination against gay and transgender people in Latin America: a correspondence study in the rental housing market. Madrid: Banco de España, June 2023. http://dx.doi.org/10.53479/30131.

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We assess the extent of discrimination against gay and transgender individuals in the rental housing markets of four Latin American countries. We conducted a large-scale field experiment based on the correspondence study methodology to examine interactions between property managers and fictitious couples engaged in searches on a major online rental housing platform. We find no evidence of discrimination against gay male couples but we do find evidence of discrimination against heterosexual couples with a transgender woman partner (trans couples). The latter receive 19% fewer responses, 27% fewer positive responses, and 23% fewer invitations to showings than heterosexual couples. We also assess whether the evidence is consistent with taste-based discrimination or statistical discrimination models by comparing response rates when couples signal being professionals with stable jobs (high SES). While we find no significant effect of the signal for high-SES heterosexual or gay male couples, trans couples benefit from this. Their call-back, positive-response, and invitation rates increase by 25%, 36% and 29%, respectively. These results suggest that discrimination against trans couples is consistent with statistical discrimination. Moreover, we find no evidence of heterosexual couples being favored over gay male couples, nor evidence of statistical discrimination for gay male or heterosexual couples.
9

Abbate, Nicolás, Inés Berniell, Joaquín Coleff, Luis Laguinge, Margarita Machelett, Mariana Marchionni, Julián Pedrazzi, and María Florencia Pinto. Discrimination Against Gay and Transgender People in Latin America: A Correspondence Study in the Rental Housing Marke. Banco Interamericano de Desarrollo, February 2023. http://dx.doi.org/10.18235/0004753.

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We assess the extent of discrimination against gay and transgender individuals in the rental housing markets of four Latin American countries. We conducted a large-scale field experiment building on the correspondence study methodology to examine interactions between property managers and fictitious couples engaged in searches on a major online rental housing platform. We find evidence of discriminatory behavior against heterosexual couples where the female partner is a transgender woman (trans couples): they receive 19% fewer responses, 27% fewer positive responses, and 23% fewer invitations to showings than heterosexual couples. However, we find no evidence of discrimination against gay male couples. We also assess whether the evidence is consistent with taste-based discrimination or statistical discrimination models by comparing response rates when couples signal high socioeconomic status (high SES). While we find no significant effect of the signal on call-back rates or the type of response for high-SES heterosexual or gay male couples, trans couples benefit when they signal high SES. Their call-back, positive-response, and invitation rates increase by 25%, 36% and 29%, respectively. These results suggest the presence of discrimination against trans couples in the Latin American online rental housing market, which seems consistent with statistical discrimination. Moreover, we find no evidence of heterosexual couples being favored over gay male couples, nor evidence of statistical discrimination for gay male or heterosexual couples.
10

Chapelet, Pierre. Analysis of the Education Management and Information System of Jamaica: Diagnosis and Proposal for Strengthening the EMIS. Inter-American Development Bank, December 2022. http://dx.doi.org/10.18235/0004619.

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This document analyzes the functioning of the Education Management and Information System (EMIS) of Jamaica, its strengths and challenges related to the key management processes and structural conditions. A survey methodology was used for the analysis of the six key management processes - (i) Physical infrastructure and equipment; (ii) Schools1; (iii) Human resources, budget and finance; (iv) Students and learning; (v) Digital content for teacher training and students learning; and (vi) Tools for strategic management - and the two structural conditions - (i) Technological infrastructure and (ii) Governance and institutional arrangements. There are several main findings. In terms of strengths, the analysis shows that the processes of human, financial and budgetary resources present the highest percentage of subprocesses in the Established level and that technological infrastructure pre-requisites are in place to sustain the improvement of the EMIS. However, EMIS sub-systems are dispersed and poorly integrated and are not covering all the needs of management processes related to the EMIS. The Ministry of Education and Youth and Information (MOEYI) also has an urgent need to develop a comprehensive and realistic strategic plan for the implementation of its EMIS and to ensure the initial and recurrent funding associated with it. Nor is there a change management plan at the MOEYI to support the evolution of the EMIS at all levels. Overall, the MOEYI is at a critical stage of its EMIS transition from a census based EMIS to a transactional information system able to track real-time information about each student, teaching and non-teaching workforce, school infrastructure and assets. This paper outlines a strengthening proposal.

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