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Добірка наукової літератури з теми "Newburn"

Автор: Grafiati

Опубліковано: 26 липня 2024

Оновлено: 27 липня 2024

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Статті в журналах з теми "Newburn"

1

Willink, David. "King & Anor v Benefice of Newburn." Ecclesiastical Law Journal 22, no. 1 (December 31, 2019): 124–25. http://dx.doi.org/10.1017/s0956618x19001509.

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2

Larrauri Pijoan, Elena. "Criminology, de T. Newburn. Cullompton: William Publishing, 2007." Revista Española de Investigación Criminológica 6 (September 15, 2008): 1–4. http://dx.doi.org/10.46381/reic.v6i0.114.

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3

BACON, MATTHEW. "Handbook of Policing, 2nd edn by T. Newburn (Ed.)." Howard Journal of Criminal Justice 48, no. 3 (July 2009): 319–20. http://dx.doi.org/10.1111/j.1468-2311.2009.00571_2.x.

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4

Stout, B. "Hinton, M. S. and Newburn, T. (2008). * POLICING DEVELOPING DEMOCRACIES." Policing 5, no. 4 (February 11, 2011): 377–78. http://dx.doi.org/10.1093/police/par015.

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5

Kirby, Stuart. "Handbook of Policing. Edited by TIM NEWBURN. Willan (2003), pp. 747." Journal of Investigative Psychology and Offender Profiling 2, no. 3 (2005): 218–19. http://dx.doi.org/10.1002/jip.24.

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6

Lyman, B. "Jones, T., and Newburn, T. (eds) (2006). * PLURAL POLICING: A COMPARATIVE PERSPECTIVE." Policing 5, no. 4 (August 19, 2011): 375–77. http://dx.doi.org/10.1093/police/par011.

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7

Marks, John M. "Book Review: Newburn, T. (Ed.). (2005). Policing: Key Readings. Portland, OR: Willan. Pp. 834." International Criminal Justice Review 17, no. 4 (December 2007): 353–54. http://dx.doi.org/10.1177/1057567707310567.

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8

Bougadi, Stavroula G. "Review of Eugene McLaughlin and Tim Newburn (eds), The SAGE Handbook of Criminological Theory." Asian Journal of Criminology 8, no. 2 (May 4, 2012): 153–55. http://dx.doi.org/10.1007/s11417-012-9140-4.

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9

Stelman, Andy. "Reviews : Just Boys Doing Business? Tim Newburn and Elizabeth Stanko (Eds) Routledge, 1994; £40 hbk." Probation Journal 42, no. 1 (March 1995): 35–36. http://dx.doi.org/10.1177/026455059504200109.

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10

Dixon, D. "Handbook of Policing. Edited By Tim Newburn (Cullompton: Willan, 2003, XXVI + 757pp., 65 hb, 28.50 pb)." British Journal of Criminology 44, no. 4 (July 1, 2004): 614–19. http://dx.doi.org/10.1093/bjc/azh058.

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Дисертації з теми "Newburn"

1

Verma, Anila. "Development of an obstetrical outcome measure to assess morbidity in newborns, newborn morbidity index." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23084.pdf.

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2

Gale, Christopher Robert Keith. "Newborn feeding and infant phenotype." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/39361.

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Breastfeeding in infancy, when compared with formula feeding, is associated with a reduced incidence of components of the metabolic syndrome later in life. One potential mechanism is via an effect on lipid metabolism and storage, manifesting as altered adiposity and ectopic lipid deposition. I have examined the null hypothesis: no association is detectable between infant feeding and adiposity or ectopic lipid in infancy, through a meta-analysis of published studies and a prospective cohort study of healthy infants employing gold standard direct measurement techniques (magnetic resonance imaging and spectroscopy). Eleven studies were identified for meta-analysis: in formula-fed compared to breastfed infants, fat mass was lower at 3-4 months [mean difference (95% confidence interval)]: [-0.09 kg (-0.18, -0.01 kg)] and 6 months [-0.18 kg (- 0.34, -0.01 kg)]. Conversely, at 12 months, fat mass was higher in formula-fed infants [0.29 kg (-0.03, 0.61 kg)] than in breastfed infants. Eighty-seven infants were included in a prospective cohort, of which 73 were investigated at two time points. In healthy, term, breastfed infants adipose tissue accretion between birth and 2-3 months ages was predominantly within subcutaneous rather than internal adipose tissue compartments, and a significant increase in intrahepatocellular lipid was detected: median [interquartile range] 0.653 [0.367-1.900] after birth and 1.837 [1.408-2.429] at 2-3 months. Comparing breastfed with formula fed infants within this cohort no significant differences were detected in total adipose tissue, adipose tissue distribution or intrahepatocellular lipid between birth and 2-3 months. Significant associations were detected between maternal BMI, rate of weight gain in early infancy and gender, and adipose tissue partitioning at 2-3 months. While method of feeding is associated with altered infant fat mass up to 6 months, no association is detectable with adipose tissue partitioning or ectopic hepatic lipid at 2-3 months.

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3

Medves, Jennifer Mary. "The practice of newborn bathing." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0008/NQ60003.pdf.

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4

Evans, N. J. "Skin permeability in the newborn." Thesis, University of Southampton, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373865.

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5

Штонда, А. О. "Особливості графічної стилістики Newborn-фотографії". Thesis, Київський національний університет технологій та дизайну, 2019. https://er.knutd.edu.ua/handle/123456789/13556.

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6

Shum-Tim, Dominique. "The protection of the newborn myocardium." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=26146.

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Definitive repair of complex congenital cardiac defects in early life has become the recent trend in pediatric cardiac surgery. This early aggressive surgical approach is to avoid the detrimental effects on the heart of chronic cyanosis, hypertrophy and volume overload which are the consequences of unrepaired congenital malformations. Adequate protection of the heart, not only during the period of corrective surgery, but also certain pre-ischemic events remain of paramount importance to the success of these operations. Profound systemic hypothermia followed by total circulatory arrest is widely used for the correction of congenital cardiac defects in the newborn. It involves a period of cold systemic perfusion on cardiopulmonary bypass before circulatory arrest is established. Using an isolated perfused piglet heart model, the first study demonstrated that prolonged cold perfusion of the immature heart could be detrimental in itself. When followed by a period of ischemic arrest, it further potentiated the myocardial injury and induced severe irreversible contracture. Further extension of this study showed that verapamil administered prior to prearrest cold perfusion could indeed minimize the functional and ultrastructural damage of prolonged myocardial cooling. This shed some light to the pathophysiology of prolonged prearrest cooling contracture of the newborn myocardium.

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7

Harpin, V. A. "The functional maturation of newborn skin." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603732.

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8

Aladangady, Dr Narendra. "Blood volume of the newborn infant." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515517.

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9

Green, Gabrielle. "Measuring pain in the newborn infant." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:5647e78c-48fb-4b1d-a54f-146803bd7037.

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Hospitalised infants require multiple painful procedures a day as part of their essential medical care. However, identifying and managing pain in non-verbal populations is challenging - the gold standard in adults is self-report of pain, but in infants we must rely on surrogate measures. In this thesis, electroencephalography (EEG), behavioural measures and physiological changes are used to investigate infant pain responses, exploring how responses to noxious stimulation are modulated by analgesics, age and pathology. It is essential to validate measures of pain in infants. As pain is both an emotional and sensory experience, noxious-evoked brain activity likely provides an important surrogate pain measure. An EEG template of noxious-evoked brain activity was validated for use in an independent group of infants: the noxiousevoked brain activity was only elicited in response to noxious stimulation and not in response to stimulation of other sensory modalities; was correlated with pain-related behaviour; and was sensitive to analgesic modulation by the use of topical local anaesthetic. This provides a novel approach, which can be used to test analgesic efficacy in infants. Behavioural responses form the cornerstone of clinical infant pain assessment. However, it is not clear whether the youngest, most premature infants are able to mount behavioural responses that can discriminate between noxious and innocuous stimulation. In this thesis, I have investigated the behavioural response to noxious and tactile stimulation in infants from 28-41 weeks corrected gestational age (CGA). The youngest infants demonstrated a lack of behavioural discrimination, being equally likely to mount a behavioural response to a tactile or a noxious stimulus. Responses diverged with increasing age, such that from approximately 32 weeks' gestation, infants were significantly more likely to display facial grimacing to noxious stimulation. Finally, the impact of pathology on pain experience has not been well studied. I have investigated how early life infection impacts pain-related responses and demonstrate, using a multidimensional approach, that infants with infection display significantly greater noxious-evoked brain activity and are more likely to mount a behavioural response compared with non-infected infants. In summary, this thesis demonstrates that responses to pain are altered by age and pathology, and provides a novel brain-derived approach to testing the efficacy of analgesic interventions in infants.

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10

Wilkinson, Dominic James Clifford. "Ethical issues in the use of magnetic resonance imaging of the brain in newborn infants with hypoxic-ischaemic encephalopathy : neuroimaging and decision-making for brain injured newborns." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:d61e4318-3568-4310-bf92-c7d70f2cb3da.

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Infants with hypoxic-ischaemic encephalopathy (birth asphyxia) have a high risk of death or disability. Those with poor prognosis are sometimes allowed to die after withdrawal of intensive care. In recent years, doctors have used new types of brain scan, magnetic resonance imaging (MRI), to predict the type and severity of impairment if the infant survives and to help with such decisions. In this thesis, I analyse the issues arising from the use of MRI for prognostication and decision-making in newborn infants. I argue that previous prognostic research has been hampered by a failure to identify and focus on the most important practical question and that this contributes to uncertainty in practice. I outline recommendations for improving research. I then look at existing guidelines about withdrawal of life-sustaining treatment. I identify several problems with these guidelines; they are vague and fail to provide practical guidance, they provide little or no genuine scope for parental involvement in decisions, and they give no weight to the interests of others. I argue that parental interests should be given some weight in decisions for newborn infants. I develop a new model of decision-making that, using the concept of a Restricted Life, attempts to set out clearly the boundaries of parental discretion in decision-making. I argue that where infants are predicted to have severe cognitive or very severe physical impairment parents should be permitted to request either withdrawal or continuation of treatment. I justify this model on the basis of overlapping interests, (prognostic, experiential and moral) uncertainty, asymmetrical harms, and the burden of care. In the conclusion, I set out a guideline for the use of MRI in newborn infants with hypoxic-ischaemic encephalopathy. I suggest that this guideline would provide a more robust, coherent and practical basis for decision-making in newborn intensive care.

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Книги з теми "Newburn"

1

Newcastle upon Tyne (England). Planning Department. Newburn local plan: Written statement. Newcastle upon Tyne: The Council, 1987.

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2

Society, Fife Family History, ed. Monumental inscriptions: Abdie, Cairneyhill, Dalgety, Markinch, Newburn, Auchterderran. [Fife?]: Fife Family History Society, 2001.

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3

Yarnell, Mary Card. Some children of the inner light: Descendants of George and Mary (Stockdale) Newburn of Bucks County, Pennsylvania, members of The Society of Friends. Mesa, Ariz. (1825 N. Stapley Dr., # 2022, Mesa 85203-2635): M.C. Yarnell, 1992.

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4

Candidus, Shelly. Newbury. Charleston, SC: Arcadia Pub., 2009.

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5

Candidus, Shelly. Newbury. Charleston, SC: Arcadia Pub., 2009.

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6

ill, Binch Caroline, ed. Newborn. New York: Dial Books for Young Readers,c, 1999.

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7

Candidus, Shelly. Newbury. Charleston, SC: Arcadia Pub., 2009.

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8

Clanchy, Kate. Newborn. London: Picador, 2004.

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9

Candidus, Shelly. Newbury. Charleston, SC: Arcadia Pub., 2009.

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10

Schatz, Howard. Newborn. Edited by Ornstein Beverly J. San Francisco: Chronicle Books, 1996.

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Частини книг з теми "Newburn"

1

Holzman, Robert S., Thomas J. Mancuso, Navil F. Sethna, and James A. DiNardo. "Newborn Medicine." In Pediatric Anesthesiology Review, 3–34. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1617-4_1.

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2

Holzman, Robert S., Thomas J. Mancuso, Navil F. Sethna, and James A. DiNardo. "Newborn Emergencies." In Pediatric Anesthesiology Review, 159–72. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1617-4_9.

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3

Mancuso, Thomas J. "Newborn Medicine." In Pediatric Anesthesiology Review, 27–53. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-60656-5_2.

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4

Mancuso, Thomas J. "Newborn Emergencies." In Pediatric Anesthesiology Review, 153–69. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-60656-5_9.

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5

Mancuso, Thomas J. "Newborn Medicine." In Pediatric Anesthesiology Review, 3–29. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-48448-8_1.

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6

Mancuso, Thomas J. "Newborn Emergencies." In Pediatric Anesthesiology Review, 153–68. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-48448-8_9.

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7

Lyons, Paul, and Nathan McLaughlin. "Newborn Evaluation." In Obstetrics in Family Medicine, 219–24. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39888-0_31.

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8

Kramer, Deborah. "Newborn Visit." In Primary Well-Being: Case Studies for the Growing Child, 85–102. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56708-2_7.

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9

Adler, Jill. "The Newborn." In Oklahoma Notes, 17–35. New York, NY: Springer New York, 1996. http://dx.doi.org/10.1007/978-1-4612-4006-8_2.

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10

Reisman, Jonathan, Jonathan M. Spector, and Linda L. Wright. "Newborn Resuscitation." In The MassGeneral Hospital for Children Handbook of Pediatric Global Health, 95–103. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7918-5_8.

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Тези доповідей конференцій з теми "Newburn"

1

Landolfi, R., R. De Cristofaro, S. De Carolis, G. Ciabattoni, and B. Bizzi. "PLACENTAL-DERIVED PGI2 INHIBITS CORD PLATELET FUNCTION: POSSIBLE ROLE OF PGI2 IN THE TRANSIENT HYPOREACTIVITY OF NEWBORN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644274.

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Previous studies on newborn platelets hyporeactivity have been performed on cord blood. In this study we demonstrated that fresh cord platelet poor plasma (C-PPP) contains a labile antiaggrega-ting substance which, added to adult platelet rich plasma (PRP), is able to reverse ADP-induced platelet aggregation. Measurements of 6-Keto-prostaglandin (PG) Fl± levels in C-PPP obtained from10 different normal newborns gave anaverage value of 1050 ± 361(SD) pg/mL. Significantly lower levelsof this prostaglandin were found in plasma samples obtained from two newborns 2 hours after the birth (mean = 150 pg/mL) and in PPP of ten control adults (mean = 25 ± 34 pg/mL). In three newborns, platelet aggregation was studied using both C-PRP and PRP obtained 2 and 48 hours after the birth. A marked reductionof platelet response to ADP and collagen was evident in C-PRP. Such hyporeactivity was mild at 2 hours and absent in the third day of life. These results show that PGI2 inhibits cord platelets and might be the cause of a transient platelet hyporeactivity in the newborn. Finally we demonstrated that washed newborn platelets, compared to adult platelets, have a significant increase ofthe apparent affinity constant (Ka)for fibrinogen and that fetal and adult fibrinogen have similar Ka for platelets.

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2

Yulianti, Ika, Rahmi Padlilah, and Agus Purnamasari. "Impact of Covid-19 Pandemic on Fetus and Newborn: A Systematic Review." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.03.68.

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ABSTRACT Background: The COVID-19 pandemic has reported the potential infection to children, including newborns. The data for the intrauterine transmission of Covid-19 during pregnancy and its impact is still limited. This study aimed to investigate the impact of Covid-19 pandemic on fetus and newborns. Subjects and Method: A systematic review was conducted by searching from PubMed, Google Scholar, JAMA, and ScienceDirect conducted in April 2020. The keywords were “child health” AND “COVID-19” OR “newborn” AND “novel coronavirus” AND “infection” OR “intrauterine transmission AND COVID- 19 AND Review”. The data were reported systematically. Results: The reviewed articles were cohort retrospective, case report, review, and systematic review. Intrauterine transmission of Covid-19 in pregnancy remained uncertain. Some studies reported the confirmation of infected Covid-19 in newborns within <2 hours to 2 days birth. Supportive therapy was given according to the clinical conditions of newborns. Conclusion: There is a lack of evidence in the intrauterine transmission of Covid-19 in pregnancy. The infected newborns with Covid-19 are confirmed within <2 hours to 2 days. Supportive therapy is conducted according to the clinical conditions of newborns. Keywords: newborns, Covid-19, infection Correspondence: Ika Yulianti. Midwifery Program, Faculty of Health Sciences, Universitas Borneo Tarakan. Jl. Amal Lama No. 1 East Tarakan, North Kalimantan. Email: ikatamaevan@gmail.com. Mobile : +628115440036. DOI: https://doi.org/10.26911/the7thicph.03.68

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3

Gu, Brian, Malvi Hemani, Barbara Kim, Angelica Herrera, Eun Yong Kim, Hyun Soo Jang, Megan Lamberti, and Anne Pigula. "Neonatal Resuscitation: A Global Perspective." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14353.

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Approximately 904,000 newborns die of breathing complications, or birth asphyxia, each year[1]. It is estimated that 30% of these deaths could be prevented[2]; however, healthcare workers in developing nations often lack the training, skills, or equipment necessary to properly resuscitate these infants. For this reason, child mortality is disproportionally clustered in low-resource locations in which the current standard of care is ineffective. The bag-valve mask resuscitator (or BVM) is the recommended treatment for a newborn who is not breathing properly.

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4

Teruel, Gilberto F., Tatiany M. Heiderich, Ruth Guinsburg, and Carlos E. Thomaz. "Analysis And Recognition Of Pain In 2d Face Images Of Full Term And Healthy Newborns." In XV Encontro Nacional de Inteligência Artificial e Computacional. Sociedade Brasileira de Computação - SBC, 2018. http://dx.doi.org/10.5753/eniac.2018.4419.

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This paper proposes a sequence of computational procedures for detecting, interpreting and classifying patterns in frontal two-dimensional images of faces for automatic recognition of pain in newborns. Using data transformation and extraction of statistical characteristics from a real-life, healthy-term newborn image database, it was possible to interpret and model the subjectivity of trained health professionals, quantifying human knowledge in the task of recognizing pain enabling automatic identification. These results were compared with NFCS based classifications by the same professionals of the same images.

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5

Christiaens, G. C. M. L. "DIAGNOSIS AND MANAGEMENT OF ITP DURING THE PERINATAL PERIOD." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644762.

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Although maternal and perinatal mortality and morbidity in pregnant patients with ITP are lower than previously assumed, they are not negligable. Significant postpartum hemorrhage occurs in 7% of the mothers with ITP. Thrombocytopenia is found in 51% of the newborns born from mothers with ITP and 6% of these have serious bleeding problems. Tests which predict which fetuses are at risk, are not yet available. Thrombocyte counts in a fetal blood sample are falsely low in 40% of cases.A prospective controlled randomized study done in the Netherlands failed to show an effect of antenatal corticosteroid treatment on neonatal platelet counts. Elective caesarean section has not been shown to protect against intracranial bleeding in thrombocytopenic newborns. The choice between vaginal delivery and caesarean section in ITP patients should be made on obstetric grounds with one exception: no other assisted vaginal delivery than the easy outlet forceps should be done. All cases of slow progress of the second stage of labour with insufficient descent should be terminated by caesarean section as well as breech delivery with suboptimal progress. Newborn thrombocyte counts should be done daily during the first week of life, since lowest platelet counts are often found between the 3rd and 5th postpartum day. Newborn thrombocytopenia is transient and does not warrant splenectomy, but can necessitate treatment with corticosteroids and/or high doses of immunoglobulin 6. Current data do not justify to dissuade breastfeeding.The recurrence of neonatal thrombocytopenia in subsequent patients is unknown.

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6

Tampy, Safitri Tia, Hari Wahyu Nugroho, and Rahmi Syuadzah. "Association between Maternal Anemia with Stunting Incidence among Newborns in Surakarta, Central Java." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.03.11.

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ABSTRACT Background: Stunting is one of the global nutrition problems, which is recorded in the six global nutrition targets in 2025. Stunting is defined as a condition when a child’s body length or height based on age and sex is below -2 SD of the median standard of child growth by World Health Organization. The prevalence of stunting in newborns in the world is 3.8%. The causes of stunting are multifactorally occurring from the age of conception to the age of two. Factors that influence stunting of newborns during the prenatal period are maternal height, maternal weight gain, anemia, and infection during pregnancy. Anemia occurs in 37% of pregnant women. Maternal anemia causes disruption in fetal growth which increases the risk of stunting at birth. This study aimed to examine the Association between maternal anemia with stunting incidence among newborns in Surakarta, Central Java. Subjects and Method: This was a cross-sectional study conducted at Sibela Community Health Center, Surakarta, Central Java. Total of 184 third trimester pregnant women and 184 newborns were enrolled in this study. The dependent variable was stunting among newborns. The independent variable was anemia in pregnant women. The data were taken from medical records in the period February-March 2020. The data were analyzed using Chi-square. Results: The prevalence of stunting among newborns was 8.2%. Anemia among pregnant women were 31.0%. Pregnant women who had anemia increase the incidence of stunting among newborns (OR = 5,19; 95% CI = 1.69 to 15.99; p = 0.002). Conclusion: There is a relationship between anemia among pregnant women and the incidence of stunting among newborns. Keywords: anemia, pregnancy, stunting, newborn Correspondence: Safitri Tia Tampy. Pediatric Research Center (PRC), Department of Pediatric Science, Dr Moewardi General Hospital, Surakarta, Central Java DOI: https://doi.org/10.26911/the7thicph.03.11

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SHEN, M. C., S. H. CHEN, and K. S. LIN. "TWO CASES OF NEONATAL PURPURA FULMINANS HOMOZYGOUS FOR PROTEIN C DEFICIENCY IN A CHINESE FAMILY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644308.

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Protein C (PC) deficiency associated with hereditary venous thromboembolic disease was first reported in 1981 and is inherited as an autosomal dominant disorder. The prevalence of heterozygous PC deficiency is estimated to be 1 to 4% in venous thrombotic diseases. The homozygous PC deficiency is even rare, and has been reported in only about 10 families througout the world. It usually presents in newborn infants as purpura fulminans or severe thrombotic disease. We herein report two newborn brothers in a Chinese family, who manifested with purpura fulminans soon after birth and died at age of 21 days and 27 days respectively. Vitamin K was administered to the second baby after birth. Both parents are not consanguineous and there were no family histories of thromboembolism on paternal and maternal sides. Blood sample was not available for specific studies in the first baby. PC antigen level by electroimmunoassay was <6% in the second baby and 49% and 60% respectively in their mother and father. Antithrombin III activity by amidolytic method was 49% in the second baby, and 90% and 97% respectively in their mother and father. Vitamin K-dependent coagulation factors and factor V were within the expected range for a newborn. Factor VIII and fibrinogen level were notably decreased. Autopsy findings of the two newborns demonstrated the similar pictures characterized by fibrin thrombi in blood vessels causing extensive hemorrhagic infarts of skin, lung, liver, kidneys, testis, urinary bladder, esophagus and brain. Our Data indicate that neonatal purpura fulminans can be familial and caused by severe homozygous PC deficiency.

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Ribeiro, Amanda Ataides, Ana Luisa Burtet, Ana Maria Marsura, Ana Gabriela Almeida Ribeiro Neto, Danielle Costa Souza, Heloisa Lemes Cardoso, João Pedro Ribeiro Barbosa Ferreira, Maria Carolina Rezende Nahime, Maria Fernanda Atavila Nogueira, and Danila Malheiros Souza. "Early weaning as a cause of cow's milk protein allergy: a review." In III SEVEN INTERNATIONAL MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/seveniiimulti2023-242.

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During the first months of life, breast milk is the main nutritional and immunological source, favoring the physical and cognitive development of the newborn (NB) (BRASIL, 2015). Early weaning consists of the interruption and insertion of other foods into the child's diet before 6 months. Even though it is beneficial, exclusive breastfeeding (EBF) is still a distant reality in many families. Given this, weaning can generate consequences for the baby, one of them being food allergies, which are immune-mediated reactions, generating inflammatory clinical responses, triggered by the intake of certain foods (BURNS et al., 2017). Cow's milk protein allergy (CMPA) is the most common and early food allergy of childhood, especially in children under 3 years of age (ZEPEDA-ORTEGA et al., 2021), due to milk proteins being the first food antigens introduced into the diet of newborns.

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MOALIC, P., Y. GRUEL, P. FOLOPPE, B. DELAHOUSSE, G. BODY, and J. LEROY. "LEVELS AND DISTRIBUTION OF FREE AND C4b-BP-B0UND-PR0TEIN S IN HUMAN FETUSES AND FULL-TERM NEWBORNS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644266.

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Levels and plasmatic distribution of protein S were studied on umbilical cordplasmas from 25 normal full-term newborns (N) and 15 normal fetuses (F) between20 and 30 weeks of gestation. Samples from fetuses were collected for antenatal diagnosis by direct puncture of the umbilical vein under high resolution real-time ultrasound. Total protein S(PS) level was determined using Laurell rocket immuno-electrophoresis (Diagnostica Stago, Asnifcres-France). Free PS wasmeasured using this latter method, afterprecipitation of C4b-BP-bound-PS by polyethylene glycol (PEG). Normal pool plasma, treated as well, was considered as the reference curve. C4b-binding protein (C4b-BP) determinations were conducted by Laurell rocket immunoelectrophoresis. The qualitative distribution of free PS and C4b-BP-bound-PS in plasma was also assessed by crossed-immunoelectrophoresis(CIE). Results (mean - SD) were expressed in percentage, in relation to healthy adults values (n = 15). Low levels of total PS were obtained in all fetuses (16.4 ±4.2) and newborns (36.4 ±9.5) as compared to adults (91.6 ± 12.2). Free protein S level was also decreased both in fetuses (22.2 ±6.0) and newborns (48.5 ± 12.1 versus 89.4 ± 26.3 in adults). At these stages of development, the ratio Free PS / Total PS (both values were obtained according to a reference curve performed with a normal adult pool plasma untreated by PEG) was significantly higher as compared to normal adults (0.82 ±0.07 in F, 0.64 ±0.17 in N and 0.39 ±0.11 in A, p‹0.001, Student t test). The predominance of free PS was also visualized in the CIE patterns. These data may be explained by undetectable C4b-BP in 21-week old fetuses (‹2% in 10 cases). After the 26th week of gestation C4b-BP level was 7.8 ±7.4 ‹n=5) and reached a value of 19.2 ±15.6 in newborns (adults = 95.7 ±14.7). In human fetus and newborn, PS essentially circulates under free form and this might compensate the decrease of the total PS level.

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Suzuki, S. "THE ABSORPTION, EXCRETION AND TRANSPLACENTAL TRANSPORT OF VITAMIN K IN THE PERINATAL PERIOD." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644262.

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It is a well-known fact that hemorrhages are observed in wholly breastfed infants beyond the neonatal period. In order to clarify vitamin K (VK)-deficiency, it is necessary to follow-up the absorption and excretion of VK2.1. To 128 cases of newborns. i) The activity of VK-dependent factors(II, VII, X) were determined by Hepaplastin test(HPT), ii) Using Latex-test, PIVKA-II was tested. We found values of HPT (Y) and PIVKA-II (X) to be inversely proportional in the relation. Y=6l.9 - 6.7 X (r= -0.3). 2. These 15 cases of hypoprothrombinemia, VK2 6mg, VK2 2mgwere given, and plasma VK2-concentration was measured by gas chromatography. After 3 hours VK2 6mgconcentration was 1030ng/ml; VK2 2mg, was 224ng/ml. This clearly shows a dose-response relation. 3. VK2 transplacental transport was also proved by using umbilical venous blood after Cesarean section. (Before Cesarean section, VK2 60mgwas given. ) In umbilical venous blood, relatively high doses of VK2 (50 - 120ng/ml) were demonstrated. Additionally, the y-carboxylglutamic acid-concentration in the urine of newborn, who received VK2-syrup was higherthan those who did not receive it.

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Звіти організацій з теми "Newburn"

1

Chi, Primus Che, and Yasser Sami Amer. What is the impact of women’s groups practising participatory learning and action on maternal and newborn health outcomes in low-resource settings? SUPPORT, 2017. http://dx.doi.org/10.30846/1703132.

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Women’s groups are one strategy to help improve maternal and newborn health outcomes. They aim to do this by increasing appropriate home prevention and care practices for mothers and newborns, and by increasing appropriate care-seeking (including antenatal care and skilled birth attendance).

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Pe-Piper, G., C. Sangster, D. J. W. Piper, and D. P. Opra. Provenance and diagenesis of sandstones in the deep wells Annapolis G-24, Balvenie B-79, Crimson F-81, Weymouth A-45, and Newburn H-23, Scotian Basin, offshore Nova Scotia. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2020. http://dx.doi.org/10.4095/326861.

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A, Bengolea, Chamorro F, Catalano HN, and Izcovich A. Assessing the safety and effectiveness of the bivalent vaccine against respiratory syncytial virus in pregnant women: a systematic review. Epistemonikos Interactive Evidence Synthesis, April 2024. http://dx.doi.org/10.30846/ies.ac54af0724.

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Objective The aim of this systematic review is to conduct a comprehensive assessment of the efficacy and safety of the bivalent vaccine against the respiratory syncytial virus (RSV) compared to the placebo or the absence of vaccination in pregnant women to inform a clinical recommendation at the internal medicine department of Hospital Alemán of Buenos Aires. Methods In order to identify randomized clinical trials that evaluate our question of interest, we carry out thorough searches in Epistemonikos and Pubmed, from the date of creation of each source until January of the year 2024. Additionally, we consider additional sources to identify referencias that could not have been identified through electronic search. Two reviewers independently selected the studies included, extracted data and evaluated the risk of bias. We perform a quantitative synthesis (meta-analysis) and prepare summary tables of findings as recommended by the Grade Group. The results of this review were presented to a team of clinical experts of the internal medicine department of Hospital Alemán of Buenos Aires who analyzed and issued judgments for each of the criteria proposed within the framework of evidence to the decision. After issuing the judgments for each criterion, experts formulated the clinical recommendation for the problem of interest. Result Through the search strategy, 331 references were identified that were examined by title and summary. Of these, 14 references for the evaluation by full text were included. Finally, 2 randomized clinical trials were included. The bivalent vaccine against RSV in pregnant women probably decreases the risk of respiratory infection, severe respiratory infection and hospitalization by RSV in the newborn. The bivalent vaccine against RSV in pregnant women probably does not increase the risk of presenting serious adverse events in the mother and does not generate an increase in non -serious adverse events (both in the mother and in the newborn). The bivalent vaccine against RSV in pregnant women could generate a slight increase in serious adverse events in the newborn (13 more events for 1,000 newborns), however the certainty of evidence is low. Clinical recommendation Based on this body of evidence, the German Hospital of Buenos Aires conditionally recommends the use of the bivalent vaccine for RSV in pregnant patients (32 to 36 weeks of gestation) (CONDITIONAL RECOMMENDATION IN FAVOR, LOW CERTAINTY IN THE EVIDENCE). Conclusions The bivalent vaccine against RSV in pregnant women presents significant benefits by reducing the risk of severe respiratory infections in newborns, supported by overall safety in pregnant women.

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A, Bengolea, Chamorro F, Catalano HN, and Izcovich A. Assessing the safety and effectiveness of the bivalent vaccine against respiratory syncytial virus in pregnant women: a systematic review. Epistemonikos Interactive Evidence Synthesis, January 2024. http://dx.doi.org/10.30846/ies.ac54af0724.v1.

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Objective The aim of this systematic review is to conduct a comprehensive assessment of the efficacy and safety of the bivalent vaccine against the respiratory syncytial virus (RSV) compared to the placebo or the absence of vaccination in pregnant women to inform a clinical recommendation at the internal medicine department of Hospital Alemán of Buenos Aires. Methods In order to identify randomized clinical trials that evaluate our question of interest, we carry out thorough searches in Epistemonikos and Pubmed, from the date of creation of each source until January of the year 2024. Additionally, we consider additional sources to identify referencias that could not have been identified through electronic search. Two reviewers independently selected the studies included, extracted data and evaluated the risk of bias. We perform a quantitative synthesis (meta-analysis) and prepare summary tables of findings as recommended by the Grade Group. The results of this review were presented to a team of clinical experts of the internal medicine department of Hospital Alemán of Buenos Aires who analyzed and issued judgments for each of the criteria proposed within the framework of evidence to the decision. After issuing the judgments for each criterion, experts formulated the clinical recommendation for the problem of interest. Result Through the search strategy, 331 references were identified that were examined by title and summary. Of these, 14 references for the evaluation by full text were included. Finally, 2 randomized clinical trials were included. The bivalent vaccine against RSV in pregnant women probably decreases the risk of respiratory infection, severe respiratory infection and hospitalization by RSV in the newborn. The bivalent vaccine against RSV in pregnant women probably does not increase the risk of presenting serious adverse events in the mother and does not generate an increase in non -serious adverse events (both in the mother and in the newborn). The bivalent vaccine against RSV in pregnant women could generate a slight increase in serious adverse events in the newborn (13 more events for 1,000 newborns), however the certainty of evidence is low. Clinical recommendation Based on this body of evidence, the German Hospital of Buenos Aires conditionally recommends the use of the bivalent vaccine for RSV in pregnant patients (32 to 36 weeks of gestation) (CONDITIONAL RECOMMENDATION IN FAVOR, LOW CERTAINTY IN THE EVIDENCE). Conclusions The bivalent vaccine against RSV in pregnant women presents significant benefits by reducing the risk of severe respiratory infections in newborns, supported by overall safety in pregnant women.

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Moza, Andreea, Florentina Duica, Panagiotis Antoniadis, Elena Silvia Bernad, Diana Lungeanu, Marius Craina, Brenda Cristiana Bernad, et al. Outcome of newborns in case of SARS-CoV-2 vertical infection. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0093.

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Review question / Objective: To identify the types and examine the range of available evidence of vertical transmission of SARS-CoV-2 from mother to newborn. To clarify the key concepts and criteria for diagnosis of SARS-CoV-2 vertical infection in neonates. To summarize the existing evidence and advance the awareness on SARS-CoV-2 vertical infection in pregnancy. Background: Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2), the virus that causes 2019 coronavirus disease (COVID-19), has been isolated from various tissues and body fluids, including the placenta, amniotic fluid, and umbilical cord of newborns. In the last few years, much scientific effort has been directed towards studying SARS-CoV-2, focusing on the different features of the virus, such as its structure and mechanisms of action. Moreover, much focus has been on developing accurate diagnostic tools and various drugs or vaccines to treat COVID-19.

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Ciapponi, Agustín. Do birth kits improve newborn and maternal outcomes? SUPPORT, 2016. http://dx.doi.org/10.30846/161012.

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Sepsis is one of the conditions contributing significantly to both maternal and newborn mortality. Poor hygiene during the intrapartum period has been recognised as a critical risk factor for sepsis. Clean birth is an essential intervention estimated to avert 20–30% of newborn deaths due to sepsis and tetanus, and requires the availability of a few essential supplies. Since birth kits have been recommended by the World Health Organization (WHO) as a means of ensuring supplies and to ‘strengthen standards of cleanliness’ in home deliveries, more than 50 low and middle income countries have introduced birth kits, which are now receiving renewed international interest.

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Ahila, S. C. Technique of managing a cleft palate in a newborn. Science Repository, July 2019. http://dx.doi.org/10.31487/j.dobcr.2019.02.04.

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Harris, Stuart, Adam Beckman, and Kevin Munro. Permanent deafness in children not identified via universal newborn hearing screening. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2023. http://dx.doi.org/10.37766/inplasy2023.5.0064.

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Whitehead, Nedra, Derek Brown, and Christine Layton. Developing a Conjoint Analysis Survey of Parental Attitudes Regarding Voluntary Newborn Screening. Research Triangle Park, NC: RTI Press, March 2010. http://dx.doi.org/10.3768/rtipress.2010.mr.0014.1002.

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Whitehead, Nedra, Derek Brown, and Christine Layton. Developing a Conjoint Analysis Survey of Parental Attitudes Regarding Voluntary Newborn Screening. Research Triangle Park, NC: RTI Press, March 2010. http://dx.doi.org/10.3768/rtipress.2010.mr.0014.1003.

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