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Готові списки джерел за темами / Molecular biology

Добірка наукової літератури з теми "Molecular biology"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 15 червня 2024

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Зміст

Статті в журналах
Дисертації
Книги
Частини книг
Тези доповідей конференцій
Звіти організацій

Статті в журналах з теми "Molecular biology":

1

D, Bhuvana. "Innovations in Molecular Biology-Cutting-Edge Breakthroughs in Molecular Genetics." Annals of Experimental and Molecular Biology 6, no. 1 (January 24, 2024): 1–4. http://dx.doi.org/10.23880/aemb-16000121.

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The field of molecular biology has experienced significant breakthroughs in recent years, driven by cutting-edge technologies and innovative research strategies. This abstract provides a concise overview of some key advancement that has shaped the landscape of molecular biology. One prominent area of progress involves the CRISPR-Cas9 gene editing system, which has revolutionized genetic manipulation. Researchers have refined and expanded its applications, enabling precise modifications to the genome for therapeutic purposes, functional genomics, and the development of genetically modified organisms. In the realm of nucleic acid sequencing, the advent of third-generation sequencing technologies has enhanced the accuracy and efficiency of deciphering complex genomes. Single-cell sequencing techniques have provided unprecedented insights into cellular heterogeneity, unraveling diverse cell populations within tissues and shedding light on the intricacies of developmental processes and disease progression. The integration of omics technologies, such as genomics, transcriptomics, proteomics, and metabolomics, has propelled systems biology to new heights. This holistic approach allows for a comprehensive understanding of biological systems, unveiling intricate molecular networks and signaling pathways. Advanced computational methods and artificial intelligence applications have played a pivotal role in processing and interpreting the vast amounts of data generated by these high-throughput techniques. Furthermore, the exploration of the microbiome's role in health and disease has gained momentum. Advances in metagenomics have enabled a deeper understanding of microbial communities, their interactions, and their impact on host physiology. The identification of specific microbial signatures associated with various diseases has opened avenues for novel therapeutic interventions and personalized medicine. Conclusion: Recent advances in molecular biology have transformed the field, offering unprecedented opportunities for scientific discovery and medical applications. The integration of cutting-edge technologies and interdisciplinary approaches continues to propel molecular biology forward, paving the way for new insights into the complexities of life at the molecular level

2

Kripke, M. L. "Biology and molecular biology." Melanoma Research 3, no. 1 (March 1993): 3. http://dx.doi.org/10.1097/00008390-199303000-00002.

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3

Yang, Yu-Chung, and Steven C. Clark. "Interleukin-3: Molecular Biology and Biologic Activities." Hematology/Oncology Clinics of North America 3, no. 3 (September 1989): 441–52. http://dx.doi.org/10.1016/s0889-8588(18)30540-9.

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4

Reuter, Jewel. "Molecular Biology." American Biology Teacher 68, no. 9 (November 1, 2006): 567–68. http://dx.doi.org/10.2307/4452065.

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5

Hirata, Mario Hiroyuki. "Molecular biology." Brazilian Journal of Pharmaceutical Sciences 47, no. 1 (March 2011): 197. http://dx.doi.org/10.1590/s1984-82502011000100032.

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6

Knittel, Thomas, and Giuliano Ramadori. "Molecular biology." Current Opinion in Gastroenterology 11, no. 3 (May 1995): 258–66. http://dx.doi.org/10.1097/00001574-199505000-00013.

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7

Lortie, Robert. "Molecular biology." Nature 364, no. 6440 (August 1993): 753. http://dx.doi.org/10.1038/364753b0.

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8

Cruz, Angela Kaysel, and Luiz Ricardo Orsini Tosi. "Molecular biology." Clinics in Dermatology 14, no. 5 (September 1996): 533–40. http://dx.doi.org/10.1016/0738-081x(96)00043-0.

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9

Pittman, Eddie. "Molecular biology." Critical Perspectives on Accounting 18, no. 6 (September 2007): 706. http://dx.doi.org/10.1016/j.cpa.2006.03.001.

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10

&NA;. "Molecular Biology." Pathology 23 (1991): 17–18. http://dx.doi.org/10.3109/00313029109060099.

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Дисертації з теми "Molecular biology":

1

Istrail, Sorin. "Computational molecular biology /." Amsterdam [u.a.] : Elsevier, 2003. http://www.loc.gov/catdir/toc/fy037/2003051360.html.

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2

Coffey, Matthew Clayton. "The molecular biology of reovirus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0001/NQ38461.pdf.

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3

King, L. A. "Molecular biology of insect picornaviruses." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370278.

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4

Garner, Sarah. "The molecular biology of Chp2." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398831.

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5

Mossman, Sally Patricia. "Investigations into the biology and molecular biology of alphaherpesvirus saimiri." Thesis, University of Liverpool, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.291968.

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6

Bantle, Stefan Franz. "The molecular biology of chicken myomesin /." Zürich, 1997. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=12157.

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7

Fange, David. "Modelling Approaches to Molecular Systems Biology." Doctoral thesis, Uppsala universitet, Molekylärbiologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-132864.

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Анотація:

Implementation and analysis of mathematical models can serve as a powerful tool in understanding how intracellular processes in bacteria affect the bacterial phenotype. In this thesis I have implemented and analysed models of a number of different parts of the bacterium E. coli in order to understand these types of connections. I have also developed new tools for analysis of stochastic reaction-diffusion models. Resistance mutations in the E. coli ribosomes make the bacteria less susceptible to treatment with the antibiotic drug erythromycin compared to bacteria carrying wildtype ribosomes. The effect is dependent on efficient drug efflux pumps. In the absence of pumps for erythromycin, there is no difference in growth between wildtype and drug target resistant bacteria. I present a model explaining this unexpected phenotype, and also give the conditions for its occurrence. Stochastic fluctuations in gene expression in bacteria, such as E. coli, result in stochastic fluctuations in biosynthesis pathways. I have characterised the effect of stochastic fluctuations in the parallel biosynthesis pathways of amino acids. I show how the average protein synthesis rate decreases with an increasing number of fluctuating amino acid production pathways. I further show how the cell can remedy this problem by using sensitive feedback control of transcription, and by optimising its expression levels of amino acid biosynthetic enzymes. The pole-to-pole oscillations of the Min-proteins in E. coli are required for accurate mid-cell division. The phenotype of the Min-oscillations is altered in three different mutants: filamentous cells, round cells and cells with changed membrane lipid composition. I have shown that the wildtype and mutant phenotypes can be explained using a stochastic reaction-diffusion model. In E. coli, the transcription elongation rate on the ribosmal RNA operon increases with increasing transcription initiation rate. In addition, the polymerase density varies along the ribosomal RNA operons. I present a DNA sequence dependent model that explains the transcription elongation rate speed-up, and also the density variation along the ribosomal operons. Both phenomena are explained by the RNA polymerase backtracking on the DNA.
Felaktigt tryckt som Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 715

8

Bäckesjö, Carl-Magnus. "Molecular biology of Bruton's tyrosine kinase /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-693-6.

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9

Jelier, Rob. "Text mining applied to molecular biology." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/10866.

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10

Ali, Manir. "The molecular biology of frutose intolerance." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388463.

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Більше джерел

Книги з теми "Molecular biology":

1

Weaver, Robert Franklin. Molecular biology. 3rd ed. Boston: McGraw-Hill, 2005.

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2

Conn, P. Michael. Receptor Molecular Biology: Receptor Molecular Biology. Burlington: Elsevier, 1995.

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3

Weaver, Robert Franklin. Molecular biology. 2nd ed. Boston: McGraw-Hill, 2002.

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4

Weaver, Robert Franklin. Molecular biology. 4th ed. Boston: McGraw-Hill, 2008.

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5

Weaver, Robert Franklin. Molecular biology. New York, NY: McGraw-Hill Education, 2016.

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6

Weaver, Robert Franklin. Molecular biology. Boston: WCB/McGraw-Hill, 1999.

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7

Elliott, William H. Biochemistry and molecular biology. 2nd ed. Oxford: Oxford University Press, 2001.

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8

Elliott, William H. Biochemistry and molecular biology. Oxford: Oxford University Press, 1997.

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9

Elliott, William H. Biochemistry and molecular biology. 3rd ed. Oxford: Oxford University Press, 2005.

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10

Elliott, William H. Biochemistry and molecular biology. 4th ed. Oxford: Oxford University Press, 2009.

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Частини книг з теми "Molecular biology":

1

Reindl, Judith, Ana Margarida Abrantes, Vidhula Ahire, Omid Azimzadeh, Sarah Baatout, Ans Baeyens, Bjorn Baselet, et al. "Molecular Radiation Biology." In Radiobiology Textbook, 83–189. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-18810-7_3.

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Анотація:

AbstractVarious exogeneous and endogenous factors constantly cause damages in the biomolecules within a cell. For example, per day, 10,000–100,000 molecular lesions occur in DNA per cell. The molecule modifications that are formed disturb the structure and function of the affected molecules. The purpose of this chapter is to introduce the damages to biomolecules caused by radiation, the associated repair pathways, and the effect on the cellular function. Special interest lies on the damages induced to DNA, the carrier of the human genome, and the consequence to genomic integrity, cell death, and cell survival. Additionally, related effects regarding inflammation and immunity, epigenetic factors, and omics are discussed. The chapter concludes with an explanation of the molecular factors of cellular hyper-radiosensitivity and induced radiation resistance.

2

Pour, Parviz M., Yoichi Konishi, Günter Klöppel, and Daniel S. Longnecker. "Molecular Biology." In Atlas of Exocrine Pancreatic Tumors, 257–64. Tokyo: Springer Japan, 1994. http://dx.doi.org/10.1007/978-4-431-68311-7_20.

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3

Emma, Francesco, Luisa Murer, and Gian Marco Ghiggeri. "Molecular Biology." In Pediatric Nephrology, 357–77. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-76341-3_14.

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4

Ignatova, Zoya, Karl-Heinz Zimmermann, and Israel Martínez-Pérez. "Molecular Biology." In DNA Computing Models, 57–98. Boston, MA: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-73637-2_3.

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5

Class, Reiner. "Molecular Biology." In Combined Modality Therapy of Central Nervous System Tumors, 37–51. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-56411-6_3.

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6

Hines, Randall S., and Leo Plouffe. "Molecular Biology." In Primary Care in Obstetrics and Gynecology, 327–37. New York, NY: Springer New York, 1998. http://dx.doi.org/10.1007/978-1-4757-2943-6_24.

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7

de Melo, Renato Miranda. "Molecular Biology." In Robotic Surgery for Abdominal Wall Hernia Repair, 145–51. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-55527-0_12.

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8

Cho, Kathleen R., and Lora Hedrick. "Molecular Biology." In Blaustein’s Pathology of the Female Genital Tract, 1173–98. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4757-3889-6_28.

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9

Neubauer, A., C. Thiede, and S. Nagel. "Molecular Biology." In New Diagnostic Methods in Oncology and Hematology, 81–111. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-58803-7_3.

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10

Hangay, George, Susan V. Gruner, F. W. Howard, John L. Capinera, Eugene J. Gerberg, Susan E. Halbert, John B. Heppner, et al. "Molecular Biology." In Encyclopedia of Entomology, 2449. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_4658.

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Тези доповідей конференцій з теми "Molecular biology":

1

Lesk, Arthur M. "COMPUTATIONAL MOLECULAR BIOLOGY." In Data For Discovery. Connecticut: Begellhouse, 2023. http://dx.doi.org/10.1615/1-56700-002-9.410.

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2

Chen, Edward S., and Daniel B. Davison. "Distributing molecular biology information." In the 1993 ACM/SIGAPP symposium. New York, New York, USA: ACM Press, 1993. http://dx.doi.org/10.1145/162754.168696.

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3

Behe, Michael J. "Theoretical Molecular Biology: Introductory Comments." In Proceedings of the Symposium. WORLD SCIENTIFIC, 2013. http://dx.doi.org/10.1142/9789814508728_others03.

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4

Xu, Songlin. "Laser applied in cell biology and molecular biology (Abstract Only)." In 1997 Shanghai International Conference on Laser Medicine and Surgery, edited by Jing Zhu. SPIE, 1998. http://dx.doi.org/10.1117/12.330170.

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5

Lipps, Jere H., Allen G. Collins, and M. A. Fedonkin. "Evolution of biologic complexity: evidence from geology, paleontology, and molecular biology." In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, edited by Richard B. Hoover. SPIE, 1998. http://dx.doi.org/10.1117/12.319851.

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6

Lu, BF, KT Lim, JM Zheng, and YY Cai. "Learning molecular biology by VR playing." In the 2004 ACM SIGGRAPH international conference. New York, New York, USA: ACM Press, 2004. http://dx.doi.org/10.1145/1044588.1044622.

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7

Pandit, SD. "Methods in Molecular Biology for Molecular Imagers I and II." In 2nd International University of Malaya Research Imaging Symposium (UMRIS) 2005: Fundamentals of Molecular Imaging. Kuala Lumpur, Malaysia: Department of Biomedical Imaging, University of Malaya, 2005. http://dx.doi.org/10.2349/biij.1.1.e7-45.

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8

Mayfield, Katia, Sara Cline, Adam Lewis, Joshua Brookover, Eric Day, William Kelley, and Stewart Sparks. "Designing a Molecular Biology Serious Educational Game." In the 2019 ACM Southeast Conference. New York, New York, USA: ACM Press, 2019. http://dx.doi.org/10.1145/3299815.3314462.

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9

Boyle, J., H. Horch, and M. Scharf. "Visualising Large Data Sets in Molecular Biology." In Proceedings of the 3rd International Workshop on Interfaces to Databases, Napier University, Edinburgh. BCS Learning & Development, 1996. http://dx.doi.org/10.14236/ewic/ids1996.4.

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10

Sadler, J. Evan. "THE MOLECULAR BIOLOGY OF VON WILLEBRAND FACTOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643930.

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Анотація:

Human von Willebrand factor (vWF) is a plasma glycoprotein that is synthesized by endothelial cells and megakaryocytes, and perhaps by syncytiotrophoblast of placenta. The biosynthesis of vWF is very complex, involving proteolytic processing, glycosyla-tion, disulfide bond formation, and sulfation. Mature vWF consists of a single subunit of ∼ 250,000 daltons that is assembled into multimer ranging from dimers to species of over 10 million daltons. vWF performs its essential hemostatic function through several binding interactions, forming a bridge between specific receptors on the platelet surface and components of damaged vascular subendothelial connective tissue. Inherited deficiency of vWF, or von Willebrand disease (vWD), is the most common genetically transmitted bleeding disorder worldwide. The last two years has been a time of very rapid progress in understanding the molecular biology of vWF. Four research groups have independently isolated and sequenced the 9 kilobase full-length vWF cDNA. The predicted protein sequence has provided a foundation for understanding the biosynthetic processing of vWF, and has clarified the relationship between vWF and a 75-100 kilodalton plasma protein of unknown function, von Willebrand antigen II (vWAgll)/ vWAgll is co-distributed with vWF in endothelial cells and platelets, and is deficient in patients with vWD. The cDNA sequence of vWF shows that vWAgll is a rather large pro-peptide for vWF, explaining the biochemical and genetic association between the two proteins. vWF has a complex evolutionary history marked by many separate gene segment duplications. The primary structure of the protein contains four distinct types of repeated domains present in two to four copies each. Repeated domains account for over 90 percent of the protein sequence. This sequence provides a framework for ordering the functional domains that have been defined by protein chemistry methods. A tryptic peptide from the amino-terminus of vWF that overlaps domain D3 binds to factor VIII and also appears to bind to heparin. Peptides that include domain A1 bind to collagens, to heparin, and to platelet glycoprotein Ib. A second collagen binding site appears to lie within domain A3. The vWF cDNA has been expressed in heterologous cells to produce small amounts of functionally and structurally normal vWF, indicating that endothelial cells are not unique in their ability to process and assemble vWF multimers. Site-directed mutagenesis has been used to show that deletion of the propeptide of vWF prevents the formation of multimers. Cloned cDNA probes have been employed to isolate vWF genomic DNA from cosmid and λ-phage libraries, and the size of the vWF gene appears to be ∼ 150 kilobases. The vWF locus has been localized to human chromosome 12p12—pter. Several intragenic RFLPs have been characterized. With them, vWF has been placed on the human genetic linkage map as the most telomeric marker currently available for the short arm of chromosome 12. A second apparently homologous locus has been identified on chromosome 22, but the relationship of this locus to the authentic vWF gene is not yet known. The mechanism of vWD has been studied by Southern blotting of genomic DNA with cDNA probes in a few patients. Three unrelated pedigrees have been shown to have total deletions of the vWF gene as the cause of severe vWD (type III). This form of gene deletion appears to predispose to the development of inhibitory alloantibodies to vWF during therapy with cryoprecipitate. During the next several years recombinant DNA methods will continue to contribute our understanding of the evolution, biosynthesis, and structure-function relationships of vWF, as well as the mechanism of additional variants of vWD at the level of gene structure.

Звіти організацій з теми "Molecular biology":

1

Jordan, Vigil C. Molecular Biology of Breast Neoplasia. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada398198.

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2

Jordan, Virgil C. Molecular Biology of Breast Neoplasia. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada430480.

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3

Jordon, Virgil C. Molecular Biology of Breast Neoplasia. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada410850.

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4

Jordan, Virgil C. Molecular Biology of Breast Neoplasia. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada421323.

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5

Jordan, V. C. Molecular Biology of Breast Neoplasia. Fort Belvoir, VA: Defense Technical Information Center, October 1997. http://dx.doi.org/10.21236/ada337851.

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6

Unni, Samir. Molecular Missionaries. New Science, August 2022. http://dx.doi.org/10.56416/480pmz.

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7

Maxwell, George L. Molecular Biology and Prevention of Endometrial Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2009. http://dx.doi.org/10.21236/ada509742.

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8

Maxwell, George L. Molecular Biology and Prevention of Endometrial Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada423688.

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9

Maxwell, George L. Molecular Biology and Prevention of Endometrial Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2006. http://dx.doi.org/10.21236/ada460283.

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10

Haygood, Margo G. Central Equipment Facility for Molecular Marine Biology. Fort Belvoir, VA: Defense Technical Information Center, March 1990. http://dx.doi.org/10.21236/ada219661.

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