Готові списки джерел за темами / Microgravity effects

Добірка наукової літератури з теми "Microgravity effects"

Автор: Grafiati
Опубліковано: 14 березня 2023

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Статті в журналах з теми "Microgravity effects"

1

SON, HOANG NGHIA, HO NGUYEN QUYNH CHI, LE NGOC PHUONG THANH, TRUONG THI HAN, NGUYEN THAI MINH HAN, DOAN CHINH CHUNG, and LE THANH LONG. "Effects of simulated microgravity on the morphology of mouse embryonic fibroblasts (MEFs)." Romanian Biotechnological Letters 25, no. 6 (October 18, 2020): 2156–60. http://dx.doi.org/10.25083/rbl/25.6/2156.2160.

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This study aimed to assess the effects of simulated microgravity on mouse embryonic fibroblast (MEF) morphology. The results showed that the area of MEFs under simulated microgravity was 7843.39 ± 551.31 µm2 which was lower than the control group (9832.72 ± 453.86 µm2). The nuclear area of MEFs under simulated microgravity (290.76 ± 4.58 µm2) and the control group (296.8 ± 4.58 µm2) did not statistically differ. In addition, the nuclear shape value of the MEFs under simulated microgravity and the control group did not statistically differ (0.86 ± 0.006 vs. 0.87 ± 0.003, respectively). The nuclear intensity of MEFs under simulated microgravity (19361 ± 852) was higher than the control group (16997 ± 285). Moreover, the flow cytometry analysis indicated the reduced G0/G1 phase cell ratio and the increased S phase and G2/M phase cell ratio in MEFs under simulated microgravity. Simulated microgravity also induced a decrease in diameter of actin filament bundles of the MEFs under simulated microgravity (1.61 ± 0.33 µm) compared to the control group (1.79 ± 0.32 µm). These results revealed that simulated microgravity is capable of inducing the morphological changes of mouse embryonic fibroblasts.
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2

Ludtka, Christopher, Erika Moore, and Josephine B. Allen. "The Effects of Simulated Microgravity on Macrophage Phenotype." Biomedicines 9, no. 9 (September 12, 2021): 1205. http://dx.doi.org/10.3390/biomedicines9091205.

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The effects of spaceflight, including prolonged exposure to microgravity, can have significant effects on the immune system and human health. Altered immune cell function can lead to adverse health events, though precisely how and to what extent a microgravity environment impacts these cells remains uncertain. Macrophages, a key immune cell, effect the inflammatory response as well as tissue remodeling and repair. Specifically, macrophage function can be dictated by phenotype that can exist between spectrums of M0 macrophage: the classically activated, pro-inflammatory M1, and the alternatively activated, pro-healing M2 phenotypes. This work assesses the effects of simulated microgravity via clinorotation on M0, M1, and M2 macrophage phenotypes. We focus on phenotypic, inflammatory, and angiogenic gene and protein expression. Our results show that across all three phenotypes, microgravity results in a decrease in TNF-α expression and an increase in IL-12 and VEGF expression. IL-10 was also significantly increased in M1 and M2, but not M0 macrophages. The phenotypic cytokine expression profiles observed may be related to specific gravisensitive signal transduction pathways previously implicated in microgravity regulation of macrophage gene and protein expression. Our results highlight the far-reaching effects that simulated microgravity has on macrophage function and provides insight into macrophage phenotypic function in microgravity.
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3

Xu, Dongqian, Shuangsheng Guo, and Min Liu. "Effects of long-term simulated microgravity on tomato seedlings." Canadian Journal of Plant Science 94, no. 2 (March 2014): 273–80. http://dx.doi.org/10.4141/cjps2013-063.

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Xu, D., Guo, S. and Liu, M. 2014. Effects of long-term simulated microgravity on tomato seedlings. Can. J. Plant Sci. 94: 273–280. Whether plants can adapt to a long-term microgravity environment is crucial to their reproduction in bioregenerative life-support systems in space. This research investigated the effects of simulated microgravity on Lycopersivon esculentum Mill. (cv. Dwarf Red-bell). Several indicators, namely germination ratio, percentage of cell membrane damage, malondialdehyde content (MDA), superoxide anion ([Formula: see text]) content, and mininucleolus, were observed 10, 20, 30, and 40 d after planting (DAP). Simulated microgravity [random positioning machine (RPM) treatment] barely had any effect on germination ratio, but it increased MDA, an index indicating membrane lipid peroxidation. Random positioning machine-treated samples had significantly higher [Formula: see text] content until 16 DAP, but these differences ceased after 21 DAP. Simulated microgravity damaged cell membranes, and the damage severity was positively related to the duration of the simulated microgravity treatment. Mininucleoli were more common in RPM-treated root tips than in the 1×g ones. In conclusion, simulated microgravity seriously disturbed tomato seedling growth by damaging cell membrane integrity, causing the accumulation of hazardous substances, and affecting the cell nucleus structure.
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4

Prasanth, Devika, Sindhuja Suresh, Sruti Prathivadhi-Bhayankaram, Michael Mimlitz, Noah Zetocha, Bong Lee, and Andrew Ekpenyong. "Microgravity Modulates Effects of Chemotherapeutic Drugs on Cancer Cell Migration." Life 10, no. 9 (August 24, 2020): 162. http://dx.doi.org/10.3390/life10090162.

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Microgravity or the condition of apparent weightlessness causes bone, muscular and immune system dysfunctions in astronauts following spaceflights. These organ and system-level dysfunctions correlate with changes induced at the single cell level both by simulated microgravity on earth as well as microgravity conditions in outer space (as in the international space station). Reported changes in single bone cells, muscle cells and white blood cells include structural/morphological abnormalities, changes in gene expression, protein expression, metabolic pathways and signaling pathways, suggesting that cells mount some response or adjustment to microgravity. However, the implications of such adjustments on many cellular functions and responses are not clear largely because the primary mechanism of gravity sensing in animal cells is unknown. Here, we used a rotary cell culture system developed by NASA to subject leukemic and erythroleukemic cancer cells to microgravity for 48 h and then quantified their innate immune response to common anti-cancer drugs using biophysical parameters and our recently developed quantum-dot-based fluorescence spectroscopy. We found that leukemic cancer cells treated with daunorubicin show increased chemotactic migration (p < 0.01) following simulated microgravity (µg) compared to normal gravity on earth (1 g). However, cells treated with doxorubicin showed enhanced migration both in 1 g and following µg. Our results show that microgravity modulates cancer cell response to chemotherapy in a drug-dependent manner. These results suggest using simulated microgravity as an immunomodulatory tool for the development of new immunotherapies for both space and terrestrial medicine.
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5

Morabito, Caterina, Simone Guarnieri, Alessandra Cucina, Mariano Bizzarri, and Maria A. Mariggiò. "Antioxidant Strategy to Prevent Simulated Microgravity-Induced Effects on Bone Osteoblasts." International Journal of Molecular Sciences 21, no. 10 (May 21, 2020): 3638. http://dx.doi.org/10.3390/ijms21103638.

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The effects induced by microgravity on human body functions have been widely described, in particular those on skeletal muscle and bone tissues. This study aims to implement information on the possible countermeasures necessary to neutralize the oxidative imbalance induced by microgravity on osteoblastic cells. Using the model of murine MC3T3-E1 osteoblast cells, cellular morphology, proliferation, and metabolism were investigated during exposure to simulated microgravity on a random positioning machine in the absence or presence of an antioxidant—the 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox). Our results confirm that simulated microgravity-induced morphological and metabolic alterations characterized by increased levels of reactive oxygen species and a slowdown of the proliferative rate. Interestingly, the use of Trolox inhibited the simulated microgravity-induced effects. Indeed, the antioxidant-neutralizing oxidants preserved cell cytoskeletal architecture and restored cell proliferation rate and metabolism. The use of appropriate antioxidant countermeasures could prevent the modifications and damage induced by microgravity on osteoblastic cells and consequently on bone homeostasis.
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6

Watenpaugh, Donald E., Jay C. Buckey, Lynda D. Lane, F. Andrew Gaffney, Benjamin D. Levine, Willie E. Moore, Sheryl J. Wright, and C. Gunnar Blomqvist. "Effects of spaceflight on human calf hemodynamics." Journal of Applied Physiology 90, no. 4 (April 1, 2001): 1552–58. http://dx.doi.org/10.1152/jappl.2001.90.4.1552.

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Chronic microgravity may modify adaptations of the leg circulation to gravitational pressures. We measured resting calf compliance and blood flow with venous occlusion plethysmography, and arterial blood pressure with sphygmomanometry, in seven subjects before, during, and after spaceflight. Calf vascular resistance equaled mean arterial pressure divided by calf flow. Compliance equaled the slope of the calf volume change and venous occlusion pressure relationship for thigh cuff pressures of 20, 40, 60, and 80 mmHg held for 1, 2, 3, and 4 min, respectively, with 1-min breaks between occlusions. Calf blood flow decreased 41% in microgravity (to 1.15 ± 0.16 ml · 100 ml−1 · min−1) relative to 1-G supine conditions (1.94 ± 0.19 ml · 100 ml−1 · min−1, P = 0.01), and arterial pressure tended to increase ( P = 0.05), such that calf vascular resistance doubled in microgravity (preflight: 43 ± 4 units; in-flight: 83 ± 13 units; P < 0.001) yet returned to preflight levels after flight. Calf compliance remained unchanged in microgravity but tended to increase during the first week postflight ( P > 0.2). Calf vasoconstriction in microgravity qualitatively agrees with the “upright set-point” hypothesis: the circulation seeks conditions approximating upright posture on Earth. No calf hemodynamic result exhibited obvious mechanistic implications for postflight orthostatic intolerance.
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7

Buravkova, Ludmila, Irina Larina, Elena Andreeva, and Anatoly Grigoriev. "Microgravity Effects on the Matrisome." Cells 10, no. 9 (August 27, 2021): 2226. http://dx.doi.org/10.3390/cells10092226.

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Gravity is fundamental factor determining all processes of development and vital activity on Earth. During evolution, a complex mechanism of response to gravity alterations was formed in multicellular organisms. It includes the “gravisensors” in extracellular and intracellular spaces. Inside the cells, the cytoskeleton molecules are the principal gravity-sensitive structures, and outside the cells these are extracellular matrix (ECM) components. The cooperation between the intracellular and extracellular compartments is implemented through specialized protein structures, integrins. The gravity-sensitive complex is a kind of molecular hub that coordinates the functions of various tissues and organs in the gravitational environment. The functioning of this system is of particular importance under extremal conditions, such as spaceflight microgravity. This review covers the current understanding of ECM and associated molecules as the matrisome, the features of the above components in connective tissues, and the role of the latter in the cell and tissue responses to the gravity alterations. Special attention is paid to contemporary methodological approaches to the matrisome composition analysis under real space flights and ground-based simulation of its effects on Earth.
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8

Kiefer, J., and H. D. Pross. "Space radiation effects and microgravity." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 430, no. 2 (December 1999): 299–305. http://dx.doi.org/10.1016/s0027-5107(99)00142-6.

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Anderson, Allison P., Jacob G. Swan, Scott D. Phillips, Darin A. Knaus, Nicholas T. Kattamis, Christine M. Toutain-Kidd, Michael E. Zegans, Abigail M. Fellows, and Jay C. Buckey. "Acute effects of changes to the gravitational vector on the eye." Journal of Applied Physiology 120, no. 8 (April 15, 2016): 939–46. http://dx.doi.org/10.1152/japplphysiol.00730.2015.

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Intraocular pressure (IOP) initially increases when an individual enters microgravity compared with baseline values when an individual is in a seated position. This has been attributed to a headward fluid shift that increases venous pressures in the head. The change in IOP exceeds changes measured immediately after moving from seated to supine postures on Earth, when a similar fluid shift is produced. Furthermore, central venous and cerebrospinal fluid pressures are at or below supine position levels when measured initially upon entering microgravity, unlike when moving from seated to supine postures on Earth, when these pressures increase. To investigate the effects of altering gravitational forces on the eye, we made ocular measurements on 24 subjects (13 men, 11 women) in the seated, supine, and prone positions in the laboratory, and upon entering microgravity during parabolic flight. IOP in microgravity (16.3 ± 2.7 mmHg) was significantly elevated above values in the seated (11.5 ± 2.0 mmHg) and supine (13.7 ± 3.0 mmHg) positions, and was significantly less than pressure in the prone position (20.3 ± 2.6 mmHg). In all measurements, P < 0.001. Choroidal area was significantly increased in subjects in a microgravity environment ( P < 0.007) compared with values from subjects in seated (increase of 0.09 ± 0.1 mm2) and supine (increase of 0.06 ± 0.09 mm2) positions. IOP results are consistent with the hypothesis that hydrostatic gradients affect IOP, and may explain how IOP can increase beyond supine values in microgravity when central venous and intracranial pressure do not. Understanding gravitational effects on the eye may help develop hypotheses for how microgravity-induced visual changes develop.
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10

Ruden, Douglas M., Alan Bolnick, Awoniyi Awonuga, Mohammed Abdulhasan, Gloria Perez, Elizabeth E. Puscheck, and Daniel A. Rappolee. "Effects of Gravity, Microgravity or Microgravity Simulation on Early Mammalian Development." Stem Cells and Development 27, no. 18 (September 15, 2018): 1230–36. http://dx.doi.org/10.1089/scd.2018.0024.

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Дисертації з теми "Microgravity effects"

1

Pardo, Steven Javier. "Effects of simulated microgravity on preosteoblast gene expression." Thesis, Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131314/unrestricted/pardo%5Fsteven%5Fj%5F200405%5Fms.pdf.

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Anderson, Rebecca K. "Effects of simulated microgravity and shear on cell behavior." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0004284.

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Poniatowski, Adam F. "Effects of simulated microgravity on human umbilical cord blood hematopoietic stem cells." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0008840.

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Farmer, Brandon. "Effects of Microgravity on Mucin Production in the Urinary Bladder in Mice." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/honors/137.

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The effects of the microgravity of spaceflight are largely unexplored with regard to biological tissues. One particular area of interest is the possible effects microgravity could have on the production of mucins. To determine the possible effects of microgravity on mucin production in the urinary bladder, we examined the transitional epithelium of the urinary bladder from female mice that were flown on the space shuttle Endeavour for 12 days in August, 2007. The flight tissue was compared to tissues from two control groups of animals, ground control and baseline. This study utilized three sets of female mice, with each set consisting of 12 animals. The three sets were designated as Flight, Ground Control, and Baseline. The flight animals were flown in the Commercial Biomedical Testing Module-2 (CBMT-2) which was housed in the shuttle’s mid-deck locker area. Ground control animals were also housed in CBTM-2 units which were kept in environmentally controlled rooms at the Space Life Sciences Lab at Kennedy Space Center. Baseline animals were also housed at the Space Life Sciences Lab but were housed in standard rodent cages with ambient temperature and humidity, with a 12/12 light dark cycle. Bladder tissue was paraffin embedded, sectioned, mounted, and histologically stained using an Alcian Blue Periodic Acid Schiff staining procedure. The bladder tissue from the three treatment groups is being qualitatively analyzed for mucin thickness and types of mucins produced. To date the study indicates that the mucin layer of the Flight tissue is thinner than that of the Baseline or Ground Control tissue, but only significantly thinner than the Baseline tissue.
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Kopp, Sascha [Verfasser]. "The effects of real and simulated microgravity on human cancer cells / Sascha Kopp." Magdeburg : Universitätsbibliothek, 2018. http://d-nb.info/1170777368/34.

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Evetts, Simon Nicholas. "Human cardiovascular baroreceptor function and blood pressure control : effects of aerobic fitness and microgravity." Thesis, King's College London (University of London), 2001. https://kclpure.kcl.ac.uk/portal/en/theses/human-cardiovascular-baroreceptor-function-and-blood-pressure-control--effects-of-aerobic-fitness-and-microgravity(13def2f6-128a-45a4-aaf8-c3cc0bf65268).html.

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Ghaderi, Yeganeh Mohammad. "Effects of preheated combustion air on laminar coflow diffusion flames under normal and microgravity conditions." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/2960.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2005.
Thesis research directed by: Mechanical Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Rosado, Helena Isabel Venancio. "Effects of simulated microgravity on the virulence properties of the opportunistic bacterial pathogen Staphylococcus aureus." Thesis, University College London (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515067.

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Woods, Chris Cory. "The effects of actual microgravity and vector-averaged gravity on the development of T cells." Diss., The University of Arizona, 2004. http://hdl.handle.net/10150/290092.

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It is well documented that long-term spaceflight adversely affects immune system function. Using fetal thymus organ culture (FTOC), we examined the effects of spaceflight and vector-averaged gravity on T cell development. In order to perform this work, we needed to design and validate a culture system that supported FTOC in a microgravity environment. The system we built, and which is described herein, served successfully for ground-based experimentation built on the principle of the clinostat. Moreover, results of testing this system at NASA's Ames Research Center demonstrated that it is optimal for future flight experimentation. This system can also be used for other cell/organ culture methodologies where three-dimensional growth and organotypic organization optimizes function for ground-based as well as spaceflight experiments. Under both conditions (spaceflight and vector-averaged gravity), the development of T cells was significantly attenuated. Exposure to spaceflight for 16 days resulted in a loss of precursors for CD4⁺, CD8⁺, and CD4⁺CD8⁺ T cells in a rat/mouse xenogeneic co-culture. A significant decrease in the same precursor cells, as well as a decrease in CD4⁻ CD8⁻ T cell precursors, was also observed in a murine C57BL/6 FTOC after rotation in a clinostat. The observed block in T cell development appeared to occur between the pre-T cell and CD4⁺CD8⁺ T cell stage. Furthermore, flow cytometric analysis clearly illustrated a reduction in the expression of IL-7Rα (CD127) in clinorotated FTOC as well as an increase in the presence of TNF-α after 4 days of culture. Levels of phosphorylated Lck were unchanged in clinorotated FTOC when compared to motional and stationary controls. These findings suggest that the full sequelae of pre-TCR signaling is dependent upon the presence of gravity. However, this alteration may be occurring downstream of Csk/Lck regulation. In support of this line of reasoning, T cell development was partially rescued in clinorotated FTOC treated with anti-CD3 monoclonal antibody. Anti-CD3 treatment presumably partially substitutes for a signal that is required for proper T cell development and is absent in the microgravity environment. These data therefore indicate that gravity indeed plays a decisive role in β-selection and in broader terms the development of T cells.
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Munro, Troy. "Heater Geometry and Heat Flux Effects On Subcooled, Thin Wire, Nucleate Pool Boiling In Microgravity." DigitalCommons@USU, 2012. https://digitalcommons.usu.edu/etd/1235.

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Nucleate boiling is widely used as a means of heat transfer in thermal management systems because of its high heat transfer rates. This study explored the effects of heat flux and surface geometry on heat transfer behavior and bubble dynamics of nucleate pool boiling in microgravity. A single platinum wire, a twist of three platinum wires, and a twist of four platinum wires were used as boiling surfaces for two separate experiments performed in microgravity on board NASA’s parabolic flight aircraft. Wire temperature, thermocouple, and video measurements were taken during a total of 44 microgravity parabolas. Results show that the crevices formed by wire twisting provide regions of localized superheating and are able to reduce the heat flux necessary for boiling onset to occur. This localized heating results in a lower average heater temperature and shortened superheating periods, but this effect decreases when more wires are present in the twist. This behavior was investigated and confirmed with a finite volume, transient conduction model. This model also showed that the water temperature profile at the bubble onset indicates that water at a certain distance from the wire surface, in this experiment 50 μm, needs to be heated to above saturation temperature in order to initiate and generate a burst of bubbles. A relative bubble area analysis method was able to quantify vapor production and bubble behavior across multiple frames of video. Application of this method revealed a transition of bubble behavior from large isolated bubbles to jet flows of small bubbles, and this method allowed the heat flux contribution of jet flows to be approximated. Additionally, a new mode of jet flows was observed. Particle image velocimetry was used to provide approximate velocities of small bubble jet flows and their influence on heat transfer to the bulk fluid.
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Книги з теми "Microgravity effects"

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International, Microgravity Combustion Workshop (6th 2001 Cleveland Ohio). Sixth International Microgravity Combustion Workshop. [Cleveland, Ohio]: National Aeronautics and Space Administration, Glenn Research Center, 2001.

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International Microgravity Combustion Workshop (6th 2001 Cleveland, Ohio). Sixth International Microgravity Combustion Workshop. [Cleveland, Ohio]: National Aeronautics and Space Administration, Glenn Research Center, 2001.

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3

Kohl, Fred J. Microgravity research at LeRC. Cleveland, Ohio: National Aeronautics and Space Administration, Lewis Research Center, 1991.

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4

Narayanan, Ramachandran, and United States. National Aeronautics and Space Administration, eds. Microgravity Materials Science Conference 2000. [Washington, D.C.]: NASA, 2001.

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5

United States. National Aeronautics and Space Administration., ed. Facilities for microgravity combustion research. [Washington, D,C.]: NASA, 1988.

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6

Russomano, Thais, Gustavo Dalmarco, and Felipe Prehn Falcão. Effects of Hypergravity and Microgravity on Biomedical Experiments, The. Cham: Springer International Publishing, 2008. http://dx.doi.org/10.1007/978-3-031-01624-0.

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7

United States. National Aeronautics and Space Administration., ed. Microgravity experiments safety and integration requirements document tree. [Washington, D.C.]: National Aeronautics and Space Administration, 1995.

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8

C, Jones J., and George C. Marshall Space Flight Center., eds. The Microgravity Research Experiments (MICREX) data base. MSFC, Ala: National Aeronautics and Space Administration, Marshall Space Flight Center, 1996.

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C, Jones J., and George C. Marshall Space Flight Center., eds. The MICrogravity Research Experiments (MICREX) data base. MSFC, Ala: National Aeronautics and Space Administration, Marshall Space Flight Center, 1996.

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10

G, Zimmerli, and United States. National Aeronautics and Space Administration., eds. Electric field effects on a near-critical fluid in microgravity. [Washington, D.C.]: National Aeronautics and Space Administration, 1994.

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Частини книг з теми "Microgravity effects"

1

Schwabe, D. "Experimental Studies of Thermal Marangoni-Effects." In Microgravity Fluid Mechanics, 201–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_21.

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2

Pletser, Vladimir. "Physiological Effects of Microgravity." In SpringerBriefs in Physics, 67–84. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8696-0_4.

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3

Nomura, Hiroshi, Michikata Kono, Jun’ichi Sato, Günther Marks, Heinrich Iglseder, and Hans J. Rath. "Effects of the Natural Convection on Fuel Droplet Evaporation." In Microgravity Fluid Mechanics, 245–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_27.

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Chen, C. F. "Surface Tension Effects on the Onset of Double-Diffusive Convection." In Microgravity Fluid Mechanics, 325–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_35.

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Meseguer, J., and J. M. Perales. "Viscosity Effects on the Dynamics of Long Axisymmetric Liquid Bridges." In Microgravity Fluid Mechanics, 37–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_4.

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Dreyer, M., A. Delgado, and H. J. Rath. "Experimental Study of Capillary Effects for Fluid Management under Microgravity Conditions." In Microgravity Fluid Mechanics, 479–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_50.

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Ryazantsev, Yu S., and A. Ye Rednikov. "Capillary Effects Associated with the Motion of a Droplet in a Homogeneous Medium." In Microgravity Fluid Mechanics, 427–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-50091-6_44.

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Russomano, Thais, Gustavo Dalmarco, and Felipe Prehn Falcão. "The Effects of Hypergravity on Biomedical Experiments." In Effects of Hypergravity and Microgravity on Biomedical Experiments, The, 39–64. Cham: Springer International Publishing, 2008. http://dx.doi.org/10.1007/978-3-031-01624-0_3.

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Russomano, Thais, Gustavo Dalmarco, and Felipe Prehn Falcão. "The Effects of Hypergravity on Biomedical Experiments." In Effects of Hypergravity and Microgravity on Biomedical Experiments, The, 17–38. Cham: Springer International Publishing, 2008. http://dx.doi.org/10.1007/978-3-031-01624-0_2.

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Marie, Pierre J. "Effects of Microgravity on Skeletal Remodeling and Bone Cells." In The Skeleton, 263–76. Totowa, NJ: Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-736-9_18.

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Тези доповідей конференцій з теми "Microgravity effects"

1

Urban, James E. "Microgravity effects on magnetotactic bacteria." In Space technology and applications international forum - 1998. AIP, 1998. http://dx.doi.org/10.1063/1.54872.

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Hirsch, David, and Harold Beeson. "Microgravity Effects on Combustion of Polymers." In International Conference On Environmental Systems. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2003. http://dx.doi.org/10.4271/2003-01-2643.

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3

Georges, Marc P., Luc Joannes, Cedric Thizy, Frank Dubois, Olivier Dupont, Philippe C. Lemaire, and Jean-Claude Legros. "Holographic camera with BSO applied to microgravity fluid experiment aboard ISS." In Photorefractive Effects, Materials, and Devices. Washington, D.C.: OSA, 2001. http://dx.doi.org/10.1364/pemd.2001.18.

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Marry, J., Y. Bernard, F. Lefaucheuh, and J. P. Cadoret. "Development of a Space Interferometer Using LiNbO3-Fe Crystal as Holographic Support." In Photorefractive Materials, Effects, and Devices II. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/pmed.1990.pd8.

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Ardestani, V. E. "Detecting the Sink-holes by Microgravity Data." In EAGE Workshop on Dead Sea Sinkholes – Causes, Effects and Solutions. Netherlands: EAGE Publications BV, 2012. http://dx.doi.org/10.3997/2214-4609.20143064.

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Sonnenfeld, Gerald, and Gerald R. Taylor. "Effects of Microgravity on the Immune System." In International Conference On Environmental Systems. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1991. http://dx.doi.org/10.4271/911515.

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Urban, James E. "Microgravity effects on the legume/Rhizobium symbiosis." In AIP Conference Proceedings Volume 387. ASCE, 1997. http://dx.doi.org/10.1063/1.52122.

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Yang, Yan, Liang-ming Pan, and Long-chang Xue. "Single Bubble Growth at Different Gravity and the Effects of Microgravity on Marangoni Convection." In 2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icone20-power2012-54300.

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Анотація:
In this paper, based on the previous experiment and the VOF (Volume of Fluid) multiphase model, the growth characteristics of a single bubble was numerically investigated in a rectangular pool boiling channel (10 mm × 10 mm × 25 mm) under micro-gravity. The transportation of mass and energy during the phase change was established by adding source term to the mass and energy equations with User Defined Function (UDF). The results showed that under microgravity, the streamline and the temperature field distribution around the bubble were significantly changed compared with the normal gravity, and the flow field and the temperature are no longer a symmetrical distribution. The bubble between microgravity and normal gravity was different from the detachment, and it does not departure from the heating wall directly under the microgravity conditions because of surface tension. But the surface tension gradient caused Marangoni effects are more significant at the smaller microgravity. The bubble growth is more complicated under the conditions of microgravity, and it is connected with the degree of the microgravity: smaller microgravity will result higher bubble growth rate. Moreover, the bubble diameter was changed more fantasticality, under microgravity and the heat transfer coefficient fluctuated more heavily with the increasing of microgravity.
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Uddin, Sardar M. Zia, and Yi-Xian Qin. "Anabolic Effects of Ultrasound as Countermeasures of Simulated Microgravity in In-Vitro and In-Vivo Functional Disuse Models." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53796.

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Microgravity (MG) during space flight has been known to cause adverse effect on bone quality. Data collected from studies done on spaceflights show loss of 1–1.6% bone mineral density (BMD) per space-flight-month[1]. Most BMD has been recorded in load-bearing bones [2]. Some studies has considered using drugs and different growth factors to maintain bone mass in microgravity conditions but it can be too expensive to maintain over longer periods of time besides the systematic effects of such treatments [3]. Considering the effects of microgravity are partially attributed to lack of mechanical force on bone tissue, which alters gene expression, reduction in transcription factors and growth factors. Furthermore, lack of gravity effects cell growth, proliferation, differentiation, cytoskeleton polymerization and cellular morphology [4, 5]. Thus to reverse these adverse effects on bone physiology, it is important to provide cells with mechanical stimulus which can provide essential mechanical signal for cells to counter the effects of microgravity. Ultrasound acoustic vibrations can be readily applied in, in vivo and human studies and has shown anabolic effects on osteopenic bone tissue [6]. Furthermore, ultrasound is a non-invasive and more target specific treatment relative to cyclic strain and vibration. The objective of this study is to see effects of low intensity pulsed ultrasound (LIPUS) on disused bone model and osteogenic activity of osteoblast cells cultures in simulated microgravity. This will help us understand that effects of ultrasound on microgravity and mechanotransduction pathway responsible for anabolic effect on bone cells.
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Li, C. T., and F. C. Lai. "Thermal Effects on Flow Injection Under Microgravity Condition." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/htd-24359.

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Abstract Numerical results for non-isothermal flow injection under microgravity condition are reported in this paper. The numerical method, which combines the finite element method with a predictor/corrector scheme, is used to determine the transient flow field. The effects of surface tension are also considered in this study. The numerical simulations have covered a wide range of the governing parameters (i.e., 1 ≤ Pe ≤ 50, 0 ≤ St ≤ 10, and Ca = 1 and ∞). From the results obtained, it shows that gravitation has an important effect on the development of the flow front and required injection pressure. Although the surface tension effects may be insignificant for isothermal flow injection at Ca &gt; 10, the effects become more important for non-isothermal flow injection at a higher Peclet number.
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Звіти організацій з теми "Microgravity effects"

1

Beem, Donald R. Conference on Combined Effects: Radiation, Microgravity, Trauma and Other Factors. Fort Belvoir, VA: Defense Technical Information Center, May 1992. http://dx.doi.org/10.21236/ada247799.

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Cheng, R. K., B. Bedat, and D. T. Yegian. Effects of buoyancy on lean premixed v-flames, Part II. VelocityStatistics in Normal and Microgravity. Office of Scientific and Technical Information (OSTI), July 1999. http://dx.doi.org/10.2172/917320.

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