Готові списки джерел за темами / Maintenance of genetic information

Добірка наукової літератури з теми "Maintenance of genetic information"

Автор: Grafiati

Опубліковано: 7 вересня 2022

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Статті в журналах з теми "Maintenance of genetic information"

Terskikh, V. V., A. V. Vasiliev, and E. A. Vorotelyak. "Maintenance of genetic information in stem cells." Russian Journal of Genetics 44, no. 3 (March 2008): 257–59. http://dx.doi.org/10.1134/s1022795408030022.

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Camci, F. "System Maintenance Scheduling With Prognostics Information Using Genetic Algorithm." IEEE Transactions on Reliability 58, no. 3 (September 2009): 539–52. http://dx.doi.org/10.1109/tr.2009.2026818.

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Liu, Qinming, and Wenyuan Lv. "Multi-component manufacturing system maintenance scheduling based on degradation information using genetic algorithm." Industrial Management & Data Systems 115, no. 8 (September 14, 2015): 1412–34. http://dx.doi.org/10.1108/imds-04-2015-0150.

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Purpose – The traditional maintenance scheduling strategies of multi-component systems may result in maintenance shortage or overage, while system degradation information is often ignored. The purpose of this paper is to propose a multi-phase model that better integrates degradation information, dependencies and maintenance at the tactical level. Design/methodology/approach – This paper proposes first a maintenance optimization model for multi-component systems with economic dependence and structural dependence. The cost of combining maintenance activities is lower than that of performing maintenance on components separately, and the downtime cost can be reduced by considering structural dependence. Degradation information and multiple maintenance actions within scheduling horizon are considered. Moreover, the maintenance resources can be integrated into the optimization model. Then, the optimization model adopting one maintenance activity is extended to multi-phase optimization model of the whole system lifetime by taking into account the cost and the expected number of downtime. Findings – The superiority of the proposed method compared with periodic maintenance is demonstrated. Thus, the values of both integrated degradation information and considering dependencies are testified. The advantage of the proposed method is highlighted in the cases of high system utilization, long maintenance durations and low maintenance costs. Originality/value – Few studies have been carried out to integrate decisions on degradation, dependencies and maintenance. Their considerations are either incomplete or not realistic enough. A more comprehensive and realistic multi-phase model is proposed in this paper, along with an iterative solution algorithm for it.

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Stavělíková, H. "Morphological characteristics of garlic (Allium sativum L.) genetic resources collection – Information." Horticultural Science 35, No. 3 (August 12, 2008): 130–35. http://dx.doi.org/10.17221/661-hortsci.

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Maintenance of garlic (Allium sativum L.) genetic resources has had a long tradition in the Czech Republic. The collection was founded in 1951 and its current holder is the Crop Research Institute, Department of Vegetables and Special Crops in Olomouc. The collection consists of 613 genotypes. The oldest genotype was acquired in 1954. The collection has been evaluated according to the Descriptor list for Allium spp. (IPGRI 2001). 17 characters of the Descriptor list were supplemented with 5 additional characters. The photos of all garlic genotypes were taken. The genotypes were divided into the three main morphological groups according to the ability to produce the scape: the first group with the scape (bolting) – 300 genotypes, the second part without the scape (non-bolting garlic) 205 genotypes and the third part presents semi-bolting garlic – 108 genotypes. The last morphological type has bulbils in the different parts of the pseudostem.

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Yang, Zhi Xin, and Chen Lei. "Intelligent Maintenance System Integrating Support Vector Machine, Isometric Mapping, Genetic Algorithm and RFID Technology." Applied Mechanics and Materials 536-537 (April 2014): 454–60. http://dx.doi.org/10.4028/www.scientific.net/amm.536-537.454.

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With the emerging of RFID technology and increasing pressure on maintenance, higher request is posed on the maintenance action. This paper introduces a combined intelligent system to complete the maintenance task. SVM and SVR model has been trained to classify machine fault types and predict the degradation. The proposed system can carry out maintenance action with the staff position information form RFID tags and the machine condition information. Genetic algorithm will be used to search the best maintenance sequence, then, the combined information will help make most efficient maintenance decision.

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MANCHANDA, SANJEEV, S. B. SINGH, and MAYANK DAVE. "CHANGE MANAGEMENT AND SOFTWARE REUSE SUPPORTIVE 'GENETIC INFORMATION SYSTEM DEVELOPMENT AND MAINTENANCE' MODEL." International Journal of Software Engineering and Knowledge Engineering 19, no. 01 (February 2009): 113–36. http://dx.doi.org/10.1142/s0218194009004076.

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The aim of the present research work is to develop an information system development process and a model for the development of new generation information systems. New age information systems are those information systems that are capable of fulfilling the demand of highly dynamic information requirements derived from the competitive environments of business organizations and support controlling the complexity involved in their maintenance and software configuration management. Present research work analyzes the theoretical, financial, technical and practical problems related to the information system development, maintenance and change management to propose an appropriate system development process and a model for the development as well as maintenance of information systems with maximum software reuse. The proposed system development process and model provide inherent support to the business organizations in having total control over information system development, maintenance and software configuration management.

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Sriskandarajah, C., A. K. S. Jardine, and C. K. Chan. "Maintenance Scheduling of Rolling Stock Using a Genetic Algorithm." Journal of the Operational Research Society 49, no. 11 (November 1998): 1130. http://dx.doi.org/10.2307/3010094.

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Sriskandarajah, C., A. K. S. Jardine, and C. K. Chan. "Maintenance scheduling of rolling stock using a genetic algorithm." Journal of the Operational Research Society 49, no. 11 (November 1998): 1130–45. http://dx.doi.org/10.1057/palgrave.jors.2600627.

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Martínez, José Alexander, and Fredy Hernán Martínez Sarmiento. "Optimization of maintenance management of trees in powerdistribution systems." Revista Tecnura 17, no. 35 (March 19, 2013): 12. http://dx.doi.org/10.14483/udistrital.jour.tecnura.2013.1.a01.

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We propose a data-analysis-based methodology for maintaining trees that affect power distribution networks. From the information captured in the field, we use fuzzy-logic-based techniques and models together with genetic algorithms so as to focus maintenance activities on the optimal time and place. The strategy is aimed at two key aspects: first, the history of failure events caused by trees on medium-voltage power supply systems; this information is used to calculate quality indicators such as energy-not-supplied (ENS) and number-of-users (NU) affected due to falling trees only. In this case we use a fuzzy-logic-based system to weight and find the critical circuits on which forest maintenance should be performed. Second, we construct an objective function based on tree-to-network distances and growth patterns of trees (classified per species) in order to simulate forest maintenance; this is achieved using a genetic algorithm to determine optimum pruning cycles for a given power supply system. We use real historical data of medium voltage circuits for system setting as well as for performance evaluation.

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Moiseyeva, Irina G. "THE STATE OF POULTRY GENETIC RESOURCES IN RUSSIA." Animal Genetic Resources Information 17 (April 1996): 73–86. http://dx.doi.org/10.1017/s1014233900000596.

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SUMMARYThis paper presents a review of past and present effort for the maintenance and improvement of breeds of chicken. This involves what is done on large state farms, in research institutes and by fancy breeders. The present sate of this genetic resources is illustrated by a long table listing all the breeds with the available information.

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Більше джерел

Дисертації з теми "Maintenance of genetic information"

Polesný, Ondřej. "Informační systém pro správu kurzů s automatickou tvorbou rozvrhů." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-236404.

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This thesis analyzes the requirements of the dance school on the software produced and designs all layers required for implementation of this product. The product manages courses, their attendees, lectors, places where the courses are held and related financial operations. It also includes an interface for automatical generation of schedules for courses according to the preferences of the dance school and course attendees. This thesis also includes detailed model of database structure, object layer model, user interface designs and describes their implementation. Furthermore this thesis includes description of communication between all parties participating in created solution and feedback from users.

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Challita, Jihane. "Study of the mechanisms reponsible for the cohesion of sister chromosomes in bacteria." Thesis, université Paris-Saclay, 2022. http://www.theses.fr/2022UPASL038.

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La maintenance de l'information génétique est essentielle pendant la prolifération cellulaire. Chez les bactéries, la réplication et la ségrégation sont concomitantes. La réplication débute à l'origine de réplication bidirectionnelle du chromosome bactérien. Deux bras de réplications sont ensuite définis, et la réplication se termine dans la région diamétralement opposée à l'origine, le terminus. Alors que la réplication progresse, les chromatides sœurs nouvellement répliquées migrent vers des côtés opposés de la cellule. Cependant, des observations par microscopie suggèrent qu'il existe un délai entre la réplication et la ségrégation qui varie le long du chromosome. Ce délai entre la réplication et ségrégation des chromatides sœurs est appelé cohésion des chromatides sœurs. Pendant ma thèse, j'ai utilisé l'outil de haute-résolution qui permet une analyse de la cohésion du génome entier (High-SC2) pour étudier le profil de cohésion de l'organisme modèle Vibrio cholerae. Il a été démontré chez E. coli que la cohésion responsable de la variation de la vitesse de ségrégation est modulée par Topoisomérase IV, une enzyme de décaténation majeure. L'un des partenaires identifiés de cette décaténase est le complexe SMC, MukBEF. Les cellules portant une délétion de mukB montrent une production de cellules anucléées, ainsi qu'une origine de réplication mal positionnée. La ségrégation des chromosomes est affectée, et la cohésion des chromatides sœurs est augmentée. L'interaction Topo IV-MukBEF est régulée par MatP qui chasserait MukBEF du terminus de réplication, facilitant ainsi l'association de MukBEF à l'origine de réplication. J'ai donc décidé d'étudier le rôle de MukB dans la formation des motifs de cohésion chez V. cholerae. Grâce à des approches génétiques couplées à l'outil High-SC2, j'ai pu démontrer que la délétion de mukB mène à une augmentation de la cohésion sur le Chr1, plus précisément sur le bras gauche, assez loin de l'origine. Mes résultats suggèrent que MukB n'agit pas préférentiellement sur des régions spécifiques, mais que ces effets différents sur les deux chromosomes de cet organisme sont dus aux différences dans leurs origines de réplication et/ou leurs systèmes de partition. De précédentes observations dans notre laboratoire ont montré qu'une double délétion de MukB et ParAB1 cause un phénotype sévère, plus important que les délétions individuelles, j'ai donc étudié les conséquences de cette double délétion sur le profil de cohésion. Mes résultats montrent une augmentation additionnelle de la cohésion dans le Chr1 près de l'origine, suggérant ainsi que le système de partition agit sur la décohésion sur le domaine de l'origine pendant que MukB agit sur le reste du chromosome. Il a été également montré que MatP retardait la ségrégation des chromatides soeurs du terminus de réplication du Chr1. J'ai utilisé le même outil qui m'a permis d'étudier le rôle de MatP dans la cohésion de cette région. J'ai pu montrer que MatP était responsable de cette cohésion uniquement au moment de la division cellulaire et non pas pendant la réplication contrairement à MukB. Mes résultats montrent également que la densité des matS présents dans le domaine ter de chaque chromosome qui influent sur la cohésion de ce même domaine
During cell proliferation, the maintenance of genetic information is essential. In bacteria, replication and segregation are concomitant. Replication starts at the single, bidirectional origin of replication of bacterial chromosomes. Two replication arms are then defined, and replication ends in a region diametrically opposite to the origin, the terminus. As replication progresses, the newly replicated sister chromosomes migrate to opposite cell compartments. However, microscopic observations suggest that there is a delay between replication and segregation, and that this delay varies along the length of chromosomes. The delay between replication and segregation of the sister copies of a genomic position is referred to as sister chromatid cohesion. During my PhD, I used the high-resolution tool that allows for a genome-wide analysis of Sister Chromatid Cohesion (High-SC2) and studied the cohesion profile of the model organism Vibrio cholerae. It has been shown in E. coli that the cohesion responsible for the variation of segregation speed is modulated by Topoisomerase IV, a major decatenating enzyme. One of the identified partners of this decatenase is an SMC complex, MukBEF. Cells carrying a mukB deletion show a production of anucleate cells, and a mispositioned origin of replication. Chromosome segregation is impaired, and therefore sister chromatid cohesion is increased overall. The Topo IV-MukBEF interaction is regulated by MatP, which seems to displace MukBEF from the terminus of replication, facilitating the association of the MukBEF complex with the origin of replication. I therefore decided to investigate the role of MukB, in the formation of the long-range patterns of cohesion in V. cholerae. Using genetic approaches coupled with the High-SC2 assay, I demonstrated that the deletion of mukB leads to an increase in cohesion on Chr1, especially on its left replication arm, far from the origin. These results suggested that MukB does not preferentially act on specific regions and that the differential effect of the mukB deletion on Chr1 and Chr2 is probably linked to differences in their origin of replication and/or partition systems. Previous observations in the lab have in fact shown that a double deletion of MukB and ParAB1 leads to a strong phenotype, thus I investigated its effect on the cohesion profile. My results show an additional increase of cohesion in Chr1 near the ori, suggesting that the partitioning system acts on the decohesion of the ori domain while MukB acts on the chromosomal arms. In addition, it has been shown that MatP kept the sister-copies of the ter domain of Chr1 together until cell division. I used the Hi-SC2 assay to study its role in the increased cohesion of this region. I showed that MatP was responsible for the cohesion of the ter1 domain at cell division not behind the replication fork, unlike MukB. My results have also shown that it is the density of the matS sites located on the ter domain of each chromosome that influence the level of cohesion of these domains

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Burkert, Christian Martin. "Cis-regulation and genetic control of gene expression in neuroblastoma." Doctoral thesis, Humboldt-Universität zu Berlin, 2021. http://dx.doi.org/10.18452/23008.

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Genregulation beeinflusst Phänotypen im Kontext von Gesundheit und Krankheit. In Krebszellen regulieren genetische und epigenetische Faktoren die Genexpression in cis. Das Neuroblastom ist eine Krebserkrankung, die häufig im Kindesalter auftritt. Es ist gekennzeichnet durch eine geringe Anzahl exonischer Mutationen und durch häufige Veränderungen der somatischen Kopienzahl, einschließlich Genamplifikationen auf extrachromosomaler zirkulärer DNA. Bisher ist wenig darüber bekannt, wie lokale genetische und epigenetische Faktoren Gene im Neuroblastom regulieren. In dieser Arbeit kombiniere ich die allelspezifische Analyse ganzer Genome (WGS), Transkriptome und zirkulärer DNA von Neuroblastom-Patienten, um genetische und cis-regulatorische Effekte zu charakterisieren. Ich zeige, dass somatische Dosis-Effekte der Kopienzahl andere lokale genetische Effekte dominieren und wichtige Signalwege regulieren. Genamplifikationen zeigen starke Dosis-Effekte und befinden sich häufig auf großen extrachromosomalen zirkulären DNAs. Die vorgestellte Analyse zeigt, dass der Verlust von 11q zu einer Hochregulation von Histonvarianten H3.3 und H2A in Tumoren mit alternativer Verlängerung der Telomere (ALT) führt, und dass erhöhte somatische Kopienzahl die Expression der TERT Gens verstärken können. Weitere Erkenntnisse sind, dass 17p-Ungleichgewichte und die damit verbundene Herunterregulierung neuronaler Gene sowie die Hochregulierung des genomisch geprägten Gens RTL1 durch Kopienzahl-unabhängige allelische Dosis-Effekte mit einer ungünstigen Prognose verbunden sind. Die cis-QTL-Analyse bestätigt eine zuvor beschriebene Regulation des LMO1 Gens durch einen Enhancer-Polymorphismus und charakterisiert das regulatorische Potenzial weiterer GWAS-Risiko-Loci. Die Arbeit unterstreicht die Bedeutung von Dosis-Effekten im Neuroblastom und liefert eine detaillierte Übersicht regulatorischer Varianten, die in dieser Krankheit aktiv sind.
Gene regulation controls phenotypes in health and disease. In cancer, the interplay between germline variation, genetic aberrations and epigenetic factors modulate gene expression in cis. The childhood cancer neuroblastoma originates from progenitor cells of the sympathetic nervous system. It is characterized by a sparsity of recurrent exonic mutations but frequent somatic copy-number alterations, including gene amplifications on extrachromosomal circular DNA. So far, little is known on how local genetic and epigenetic factors regulate genes in neuroblastoma to establish disease phenotypes. I here combine allele-specific analysis of whole genomes, transcriptomes and circular DNA from neuroblastoma patients to characterize genetic and cis-regulatory effects, and prioritize germline regulatory variants by cis-QTLs mapping and chromatin profiles. The results show that somatic copy-number dosage dominates local genetic effects and regulates pathways involved in telomere maintenance, genomic stability and neuronal processes. Gene amplifications show strong dosage effects and are frequently located on large but not small extrachromosomal circular DNAs. My analysis implicates 11q loss in the upregulation of histone variants H3.3 and H2A in tumors with alternative lengthening of telomeres and cooperative effects of somatic rearrangements and somatic copy-number gains in the upregulation of TERT. Both 17p copy-number imbalances and associated downregulation of neuronal genes as well as upregulation of the imprinted gene RTL1 by copy-number-independent allelic dosage effects is associated with an unfavorable prognosis. cis-QTL analysis confirms the previously reported regulation of the LMO1 gene by a super-enhancer risk polymorphism and characterizes the regulatory potential of additional GWAS risk loci. My work highlights the importance of dosage effects in neuroblastoma and provides a detailed map of regulatory variation active in this disease.

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Uimaniemi, L. (Leena). "Maintenance of genetic diversity in four taiga specialists." Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274105.

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Abstract Genetic diversity in three taiga specialists – the Siberian tit (Parus cinctus), the Siberian jay (Perisoreus infaustus) and the Siberian flying squirrel (Pteromys volans) – was assessed by comparing DNA sequence variation across the mitochondrial control region and allele frequencies of microsatellites from samples collected from Fennoscandia and Siberia. Population sizes of these species have declined in association with fragmentation and loss of suitable forest habitat due to modern forestry practices in Fennoscandia. The red squirrel (Sciurus vulgaris) served as a reference for the flying squirrel. Genetic differentiation among species studied ranged from a panmictic population in the Siberian tit to that of the strong differentiation of populations (θST = 53%) in the flying squirrel in Finland. MtDNA and microsatellite data, together with assignment studies, showed the Siberian jay population to be significantly genetically structured and supported the existence of a metapopulation like structuring in Fennoscandia. Division of genetic variation among flying squirrel populations along the ancient shoreline of the Littorina Lymnea Sea stage of the Baltic Sea (7000 BP) and two geographically associated branches in the minimum spanning network supported a two-way colonisation history for the species. The Finnish inland appears to have been colonised from the east in association with the arrival of Norway spruce. At the same time, Coastal Finland was colonised from the south-east through the Karelian Isthmus. Gene flow of the species appeared female biased and restricted. Species exhibiting more restrictive dispersal characteristics and habitat requirements possessed stronger population genetic structure than those with opposite characteristics. Growth or contractions in population size leave characteristic signatures in mtDNA that can be studied by comparing different sequence diversity estimates among populations. I applied this method to the species studied. Significant differences in nucleotide diversities indicated restrictions in gene flow among populations in all species studied. Half of the Siberian jay populations gave a signal of population size bottleneck. All the species studied showed differences in their population genetic structures across their entire distribution ranges consistent with the multirefugia model, most likely to be attributable to differences in their ecological characteristics and Pleistocene histories.

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Trotter, Meridith V., and n/a. "Frequency-dependent selection and the maintenance of genetic variation." University of Otago. Department of Zoology, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081114.120926.

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Frequency-dependent selection has long been a popular heuristic explanation for the maintenance of genetic diversity in natural populations. Indeed, a large body of theoretical and empirical work has already gone into elucidating the causes and consequences of frequency-dependent selection. Most theoretical work, to date, has focused either on the diallelic case, or dealt with only very specific forms of frequency-dependence. A general model of the maintenance of multiallelic genetic diversity has been lacking. Here we extend a flexible general model of frequency-dependent selection, the pairwise interaction model, to the case of multiple alleles. First, we investigate the potential for genetic variation under the pairwise interaction model using a parameter-space approach. This approach involves taking a large random sample of all possible fitness sets and initial allele-frequency vectors of the model, iterating each to equilibrium from each set of random initial conditions, and measuring how often variation is maintained, and by which parameter combinations. We find that frequency- dependent selection maintains full polymorphism more often than classic constant-selection models and produces more skewed equilibrium allele frequencies. Fitness sets with some degree of rare advantage maintained full polymorphism most often, but a variety of non-obvious fitness patterns were also found to have positive potential for polymorphism. Second, we further investigate some unusual dynamics uncovered by the parameter-space approach above. Long-period allele-frequency cycles and a small number of aperiodic trajectories were detected. We measured the number, length and domains of attraction of the various attractors produced by the model. The genetic cycles produced by the model did not have periods short enough to be observable on an ecological time scale. In a real world system, allele-frequency cycling is likely to be indistinguishable from stable equilibrium when observed over short time scales. Third, we use a construction approach to model frequency-dependent selection with mutation under the pairwise interaction model. This approach involves the construction of an allelic polymorphism by bombarding an initial monomorphism with mutant alleles over many generations. We find that frequency-dependent selection is able to generate large numbers of alleles at a single locus. The construction process generates a wide range of allele- frequency distributions and genotypic fitness relationships. We find that constructed polymorphisms remain permanently invasible to new mutants. Analysis of constructed fitness sets may even reveal a signature of positive frequency dependence. Finally, we examine the numbers and distributions of fitnesses and alleles produced by construction under the pairwise interaction model with mutation from existing alleles, using several different methods of generating mutant fitnesses. We find that, relative to more general construction models, generating mutants from existing alleles lowers the average number of alleles maintained by frequency-dependent selection. Nevertheless, while the overall numbers of alleles are lower, the polymorphisms produced are more stable, with more natural allele-frequency distributions. Overall, frequency-dependent selection remains a powerful mechanism for the maintenance of genetic variation, although it does not always work in intuitively obvious ways.

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Barton, Alison. "Maintenance of visuospatial information in working memory." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315980.

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Srinivasan, Rengarajan. "Impact of information availability on maintenance decisions." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610029.

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Al-Douri, Yamur K. "Information assurance for maintenance of railway track." Licentiate thesis, Luleå tekniska universitet, Drift, underhåll och akustik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-26609.

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Railway traffic is steadily increasing, having a negative impact on maintenance and resulting in decreased track availability, comfort, and safety. Swedish railway track maintenance mostly focuses on the actual track condition via a nationwide condition-based maintenance (CBM) strategy. For maintenance to be conducted in an appropriate way, data on the actual track condition must be accurate; furthermore, those data need to be converted into accurate information for maintenance decisions. An information assurance (IA) framework has the potential to deal with the system risks from a technical perspective. The framework is a guideline that can be implemented within CBM to understand both condition monitoring data behaviour and the information processing used to reach maintenance decisions.This research investigates ways of an information assurance (IA) framework can be implemented in the following CBM steps: data collecting, data processing and making maintenance decisions on Swedish railway. The framework can be used to understand data behaviour, information processing and the communication between information layers for decisions at organisation, infrastructure and data/information levels. The research uses both qualitative and quantitative methods to investigate critical information data, parameters, and problems and to suggest which areas need improvement. Quantitative analysis of the Swedish track geometry database reveals specific information about the behaviour of the railway data and their processing to make maintenance decisions.A case study shows how certain sections of a railway track are monitored and evaluates maintenance practices on those sections. The study finds several different types of measurements are taken using several different measurement systems. It is difficult to integrate these data for proper processing. In addition, there are problems of incomplete or irregular data; this affects the derivation of information and the use of models to understand track irregularities.Given the problems of data processing and subsequent decision making, the study suggests implementing an IA framework with CBM. The study checks the achievement of three IA principles in the existing data: authenticity, integrity and availability. The results show data have problems of authenticity and integrity, something also mentioned by the stakeholders in interviews. In particular years and on certain track sections, CM data are more than 5 percent incomplete, significantly affecting analysis. Incomplete track measurement data reach as high as 63 percent for the parameters of standard deviation (STD), longitudinal level and STD cooperation. Inaccurate measured values for alignment long wavelength within certain speed limits reach as high as 71 percent. These indicators are important for calculating track quality but are either incomplete or incorrect, negatively affecting the calculation of the Q-value and estimations of the track quality. This, in turn, negatively affects the maintenance decisions. Using information assurance will increase the system performance by permitting stakeholders to make accurate decisions.The suggested information assurance framework can discover technical problems but it needs to be improved using technologies, techniques and services to ensure complete and accurate data are available to be processed for maintenance decisions.

Godkänd; 2016; 20160509 (yamald); Nedanstående person kommer att hålla licentiatseminarium för avläggande av teknologie licentiatexamen. Namn: Yamur K. Al-Douri Ämne: Drift och underhållsteknik /Operation and Maintenance Engineering Uppsats: Information Assurance for Maintenance of Railway Track Examinator: Professor Uday Kumar, Institutionen för samhällsbyggnad och naturresurser, Avdelning: Drift, underhåll och akustik, Luleå tekniska universitet. Diskutant: Dr Rikard Granström, Trafikverket, Luleå. Tid: Fredag 10 juni, 2016 kl 10.00 Plats: F1031, Luleå tekniska universitet

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Gethers, Malcom Bernard II. "Information Integration for Software Maintenance and Evolution." W&M ScholarWorks, 2012. https://scholarworks.wm.edu/etd/1539720326.

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Software maintenance and evolution is a particularly complex phenomenon in the case of long-lived, large-scale systems. It is not uncommon for such systems to progress through years of development history, a number of developers, and a multitude of software artifacts including millions of lines of code. Therefore, realizing even the slightest change may not always be straightforward. Clearly, changes are the central force driving software evolution. Therefore, it is not surprising that a significant effort has been (and should be) devoted in the software engineering community to systematically understanding, estimating, and managing changes to software artifacts. This effort includes the three core change related tasks of (1) expert developer recommendations - identifying who are the most experienced developers to implement needed changes, (2) traceability link recovery recovering dependencies (traceability links) between different types of software artifacts, and (3) software change impact analysis - which other software entities should be changed given a starting point.;This dissertation defines a framework for an integrated approach to support three core software maintenance and evolution tasks: expert developer recommendation, traceability link recovery, and software change impact analysis. The framework is centered on the use of conceptual and evolutionary relationships latent in structured and unstructured software artifacts. Information Retrieval (IR) and Mining Software Repositories (MSR) based techniques are used for analyzing and deriving these relationships. All the three tasks are supported under the framework by providing systematic combinations of MSR and IR analyses on single and multiple versions of a software system. Our approach to the integration of information is what sets it apart from previously reported relevant solutions in the literature. Evaluation on a number of open source systems suggests that such combinations do offer improvements over individual approaches.

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Tapio, M. (Miika). "Origin and maintenance of genetic diversity in northern European sheep." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:9514282353.

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Abstract The Nordic and Baltic countries and North-western Russia have >20 old native sheep breeds. These together with recently synthesized breeds and local populations of international breeds make up the northern European sheep diversity. Changes in agriculture threaten to erode genetic diversity in sheep. Molecular genetic variation was assessed to understand genetic diversity in northern European sheep. Distribution of maternal lineages were studied based on mitochondrial control region variation in 76 sheep breeds in northern Europe and in a wide neighbouring area extending to the Caucasus and Central-Asia. Autosomal microsatellite variation was studied in 37 northern European breeds, and autosomal blood protein variation was studied in six Finnish and Russian breeds. Four distinct maternal lineages were observed in Eurasian sheep. Their distribution agrees with sheep expansion starting from the Near East. Two most common distinct lineages were recorded in northern Europe. Majority of northern sheep have the lineage, which predominates in other parts of Europe. Results suggest that the main maternal origin of northern sheep is in the south. However, rare "Asian" lineage was observed in several old northern European breeds. The rare type in the Nordic sheep is descendant to the type observed in the Middle Volga region, which suggest that some sheep were brought to northern Europe from the east. Microsatellites showed clustering of geographically neighbouring sheep, when breed locations are corrected for the recent transportations. The analysis separated long and short-tailed sheep, although this macroscale structure explains a small proportion of breed differences. Differentiation among the northern European breeds is stronger than typically observed in sheep. Many native breeds are less inbred than the local populations of the international breeds, but some rare breeds and subpopulations of divided unofficial strains were inbred. Some breeds require more careful maintenance due to recent population size reduction. Maintaining prolificacy in breeds such as the Finnsheep and the Romanov may require efficient avoidance of inbreeding. The breeds were ranked for conservation using simultaneously within-breed variation and breed divergence. Set of important breeds included seven rare old native breeds or strains which merit efficient conservation measures urgently.

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Книги з теми "Maintenance of genetic information"

Thompson, Alison K., and Ruth F. Chadwick, eds. Genetic Information. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/b102404.

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Link, William R. Integrated Maintenance Information System (IMIS): A maintenance information delivery concept. Brooks Air Force Base, Tex: Air Force Human Resources Laboratory, Air Force Systems Command, 1987.

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Tomlingson, Paul D. Maintenance management information systems. 2nd ed. New York, NY: McGraw-Hill, 1985.

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Widdows, Heather, and Caroline Mullen, eds. The Governance of Genetic Information. Cambridge: Cambridge University Press, 2009. http://dx.doi.org/10.1017/cbo9780511635274.

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Sándor, Judit. Society and genetic information: Codes and laws in the genetic era. Budapest, Hungary: Central European University Press, 2004.

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Judit, Sándor. Society and genetic information: Codes and laws in the genetic era. Budapest, Hungary: Central European University Press, 2004.

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Juth, Niklas. Genetic information values and rights: The morality of presymptomatic genetic testing. Göteburg: Acta Universitatis Gothoburgensis, 2005.

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Robertson, Alexander M. Use of genetic algorithms in information retrieval. [London]: British Library Research and Development Department, 1995.

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Scanlon, Colleen. Managing genetic information: Implications of nursing practice. Washington DC: American Nurses Pub., 1995.

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service), SpringerLink (Online, ed. Cartesian Genetic Programming. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2011.

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Частини книг з теми "Maintenance of genetic information"

Ohira, Ryoma, Md Saiful Islam, Jun Jo, and Bela Stantic. "LCS Based Diversity Maintenance in Adaptive Genetic Algorithms." In Communications in Computer and Information Science, 56–68. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6661-1_5.

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Srinivasan, Dipti, and Irfan Mulyawan Malik. "Flexible Generator Maintenance Scheduling in a Practical System Using Fuzzy Logic and Genetic Algorithm." In Hybrid Information Systems, 395–413. Heidelberg: Physica-Verlag HD, 2002. http://dx.doi.org/10.1007/978-3-7908-1782-9_29.

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Lewandowski, Marco, Oliver Siebenand, Stephan Oelker, and Bernd Scholz-Reiter. "Maintenance Work Order Based on Event-Driven Information of Condition-Monitoring Systems—A Genetic Algorithm for Scheduling and Rescheduling of Dynamic Maintenance Orders." In Dynamics in Logistics, 395–404. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35966-8_33.

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Robinson, Richard, Uno Danielson, and Martin Snaith. "Management Information." In Road Maintenance Management, 121–60. London: Macmillan Education UK, 1998. http://dx.doi.org/10.1007/978-1-349-14676-5_5.

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Galar, Diego, Kai Goebel, Peter Sandborn, and Uday Kumar. "Information in Maintenance." In Prognostics and Remaining Useful Life (RUL) Estimation, 1–44. New York: CRC Press, 2021. http://dx.doi.org/10.1201/9781003097242-1.

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Zhegunov, Gennadiy. "Genetic Information." In The Dual Nature of Life, 219–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-30394-4_21.

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Roff, Derek A. "The Maintenance of Genetic Variation." In Evolutionary Quantitative Genetics, 339–87. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-4080-9_9.

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Arnaiz, Aitor, Benoit Iung, Adam Adgar, Tonu Naks, Avo Tohver, Toomas Tommingas, and Eric Levrat. "Information and Communication Technologies Within E-maintenance." In E-maintenance, 39–60. London: Springer London, 2010. http://dx.doi.org/10.1007/978-1-84996-205-6_3.

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Burke, E. K., J. A. Clarke, and A. J. Smith. "Four Methods for Maintenance Scheduling." In Artificial Neural Nets and Genetic Algorithms, 264–69. Vienna: Springer Vienna, 1998. http://dx.doi.org/10.1007/978-3-7091-6492-1_58.

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Zhang, Jianzhi. "Genetic Redundancies and Their Evolutionary Maintenance." In Evolutionary Systems Biology, 279–300. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-3567-9_13.

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Тези доповідей конференцій з теми "Maintenance of genetic information"

"A HYBRIDIZED GENETIC ALGORITHM FOR COST ESTIMATION IN BRIDGE MAINTENANCE SYSTEMS." In 12th International Conference on Enterprise Information Systems. SciTePress - Science and and Technology Publications, 2010. http://dx.doi.org/10.5220/0002974304280433.

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Lv, Sichao, Hui Wang, and Wenzhou Sun. "Research on optimization model and algorithm of aircraft maintenance plan based on Improved Genetic algorithm." In ICISCAE 2021: 2021 IEEE 4th International Conference on Information Systems and Computer Aided Education. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3482632.3484014.

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Tamilselvan, Prasanna, Yibin Wang, and Pingfeng Wang. "Prognosis Informed Design Framework for Operation and Maintenance of Wind Turbines." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-70792.

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Advances in high performance sensing and signal processing technology enable the development of failure prognosis tools for wind turbines to detect, diagnose, and predict the system-wide effects of failure events. Although prognostics can provide valuable information for proactive actions in preventing system failures, the benefits have not been fully utilized for the operation and maintenance decision making of wind turbines. This paper presents a generic failure prognosis informed decision making tool for wind farm operation and maintenance while considering the predictive failure information of individual turbine and its uncertainty. In the presented approach, the probabilistic damage growth model is used to characterize individual wind turbine performance degradation and failure prognostics, whereas the economic loss measured by monetary values and environmental performance measured by unified carbon credits are considered in the decision making process. Based on the customized wind farm information inputs, the developed decision making methodology can be used to identify optimum and robust strategies for wind farm operation and maintenance in order to maximize the economic and environmental benefits concurrently. The efficacy of proposed prognosis informed maintenance strategy is compared with the condition based maintenance strategy and demonstrated with the case study.

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Lokagariwar, Dhaval, and Bernhard Bettig. "Purely Declarative Feature-Based Design With Feature Type Property Maintenance." In ASME 2004 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/detc2004-57360.

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Commercial feature-based design systems are based on describing the design model in some form of sequential representation of primitive shapes and operations called features. In these systems, the overall design process, the behavior of building blocks and the characteristics of the final model, are governed by the construction sequence. These systems do not check for the conformity of the final shape with the actual design intent of features, and allow their design and engineering intent to be altered during the design process. The research work presented here describes a new design methodology and feature representation for facilitating a design environment that is independent of any construction order or constraint-based dependencies and provides a mechanism for maintaining design and engineering intent of the design features. The methodology works by dynamically evaluating the features using a planning algorithm such that the validity of each feature is maintained. These are intended to serve as a generic template that can be used to design and develop specific design features and CAD software systems.

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Jessop, Simon, Scott Valentine, and Michael Roemer. "CBM Integrated Maintenance Scheduler." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-51375.

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Condition Based Maintenance (CBM) is a key technology enabling facility maintenance cost reduction. The CBM approach to maintenance replaces rigid time-based maintenance schedules with the “right maintenance at the right time” identified by real-time equipment health monitoring. This approach creates a new requirement for determining the best time to schedule newly identified critical maintenance actions in light of the real world constraints of available labor and resources. One of the major challenges encountered when attempting to optimize a maintenance schedule is related to the resolution of the many and often complex interdependencies or constraints present throughout the maintenance process. This paper presents a CBM decision support software tool that leverages real-time current and future health condition information to optimize maintenance resources, tasking, and planning in order to maximize the system readiness. Over the past year Impact Technologies, under contract by NAVSEA, has been developing technologies that will provide the necessary decision support tools to address this dynamic maintenance environment. The software scheduling tool utilizes an Open Systems Architecture for Condition-Based Maintenance (OSA-CBM) architecture to facilitate implementation into new or legacy systems. The tool employs a generic maintenance model that accounts for equipment reliability attributes, maintenance task material and labor requirements, system dependencies, and subsystems relationships. The focus of the development has been on Naval Ship maintenance, but the model inputs can be adapted to a variety of applications including power generators, aircraft, ships, and production facilities. The core of the decision support tool is a multi-sweep optimization algorithm that is tuned to the maintenance scheduling problem. The algorithm has been designed to achieve the best computational speed. Benefits and risks of maintenance decisions have been quantified in risk, which can be defined in terms of readiness or financial. The probability and consequence of each system failure are considered in light of the complex system interdependencies, such as dependant and redundant systems, to achieve the best overall system readiness. Novel post-processing steps identify the active solution constraints further enhancing the user’s ability to understand the issues that affect system availability.

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Tamilselvan, Prasanna, Yibin Wang, Pingfeng Wang, and Janet M. Twomey. "Prognosis Informed Stochastic Decision Making Framework for Operation and Maintenance of Wind Turbines." In ASME/ISCIE 2012 International Symposium on Flexible Automation. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/isfa2012-7168.

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Ribeiro, Robison T., Marcio Single, and Reinaldo F. Sima. "Handheld PC Used in Field Maintenance of the GASBOL Pipeline: A Case Study." In 2004 International Pipeline Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/ipc2004-0273.

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One of the most important challenges in maintenance and integrity is the correct register of maintenance data. Information about failures, diagnostics and services execution are extremely important for the background history of equipments and future analysis. Field personnel usually supply the information in the CMMS (Computerized Maintenance Management System) in the form of few words (or key words) written in a notepad, agenda or at the backside of a maintenance work order. Therefore, most of the time the quality of data is very low, registries are very poor, information is generic and does not add value to the background history of equipment. Sometimes these data are not really true; they are only remembrances from the maintenance worker’s memory. In natural gas pipeline companies, like TBG, with large extensions of pipes and installations distributed so far from each other it is usual that maintenance personnel go to the field job and sometimes do not come back to the office at the same day. In addition, the need to access the corporate network to input maintenance data in the Maintenance Module of Enterprise Resource Planning means that maintenance registries are something that do not flow easily from field to database. Technicians also spend a lot of time in front of the computer decreasing their productive working hours. Being aware of the importance of data to a consistent integrity pipeline program and to solve the problems related above, TBG implemented Maintenance in the Palm of the Hand project and distributed handheld PCs to all technicians, with software that works like an electronic maintenance work order. This system permits to collect maintenance data in real time (timesheet, measurements and information about the job and related problems) and also providing important information to help technicians perform their jobs (equipment data, set points and task list). If necessary, they can start a maintenance request. At any moment it is possible to connect to the corporate network and download data to CMMS. This project allowed TBG to increase quality and reliability of maintenance data and speed of information flow from field to CMMS, eliminating the need to print work orders and data sheets, increasing the productivity of technicians and reducing the time spent on boring tasks such as taking notes.

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Baysal, Mehmet Murat, Utpal Roy, Rachuri Sudarsan, Ram D. Sriram, and Kevin W. Lyons. "Product Information Exchange Using Open Assembly Model: Issues Related to Representation of Geometric Information." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-82812.

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The objective of this paper is to discuss the main issues for product information exchange through the Open Assembly Model (OAM). The OAM model provides a base level product model that is open, simple, generic, expandable, independent of any vendor software and product development process, and capable of engineering context that is shared throughout the product lifecycle. Two of the main issues in the OAM model are the representation of geometric information of the artifacts (and assembly features) and maintenance of the consistency of the product information among relevant classes based on geometry information. This paper considers the geometry information at three levels: 1) basic geometric information of artifact with position and orientation information, 2) assembly features and their interrelations, and 3) detailed geometric information of all features in the artifact. In addition to geometric information, other relations/associations between the classes in the Unified Modeling Language (UML) based OAM model are maintained by constraints written in Object Constraint Language (OCL). This information structure in the UML and OCL is then mapped into the Extensible Markup Language (XML) for easy information exchange. XML is commonly used and supported by many softwares. Therefore, integration of XML with UML will provide an excellent tool for internet based collaboration.

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Groenewegen, Marco W. M., Milton E. Aguirre, and Just L. Herder. "Design of a Partially Compliant, Three-Phalanx Underactuated Prosthetic Finger." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-47055.

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Advanced robotic hand prostheses are praised for their impressive robust and fine grasping capabilities generated from intricate systems. Nevertheless, a high demand remains for grasping mechanisms that are mechanically simple, lightweight, and cheap to produce, easy to assemble and low in maintenance costs. This paper presents the design of a partially compliant underactuated finger to demonstrate the feasibility of achieving these rigorous requirements. The conceptual topology of the three phalanx finger is selected based on competitive analysis. Employing Pseudo-Rigid Body Model and Finite Element Analysis, a genetic optimization problem is formulated to minimize bending stresses within compliant flexures. The result is a fully functional demonstrator capable of flexing 180° in finger rotation. The prototype is fabricated from flexible high strength nylon and requires no assembly steps beyond 3D printing. Experimental testing verifies the design method with an acceptable error of < 5%.

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Tsoutsanis, E., Y. G. Li, P. Pilidis, and M. Newby. "Part-Load Performance of Gas Turbines: Part II — Multi-Point Adaptation With Compressor Map Generation and GA Optimization." In ASME 2012 Gas Turbine India Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/gtindia2012-9581.

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Accurate gas turbine performance simulation is a vital aid to the operational and maintenance strategy of thermal plants having gas turbines as their prime mover. Prediction of the part load performance of a gas turbine depends on the quality of the engine’s component maps. Taking into consideration that compressor maps are proprietary information of the manufacturers, several methods have been developed to encounter the above limitation by scaling and adapting component maps. This part of the paper presents a new off-design performance adaptation approach with the use of a novel compressor map generation method and Genetic Algorithms (GA) optimization. A set of coefficients controlling a generic compressor performance map analytically is used in the optimization process for the adaptation of the gas turbine performance model to match available engine test data. The developed method has been tested with off-design performance simulations and applied to a GE LM2500+ aeroderivative gas turbine operating in Manx Electricity Authority’s combined cycle power plant in the Isle of Man. It has been also compared with an earlier off-design performance adaptation approach, and shown some advantages in the performance adaptation.

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Звіти організацій з теми "Maintenance of genetic information"

Seale, Maria, Natàlia Garcia-Reyero, R. Salter, and Alicia Ruvinsky. An epigenetic modeling approach for adaptive prognostics of engineered systems. Engineer Research and Development Center (U.S.), July 2021. http://dx.doi.org/10.21079/11681/41282.

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Prognostics and health management (PHM) frameworks are widely used in engineered systems, such as manufacturing equipment, aircraft, and vehicles, to improve reliability, maintainability, and safety. Prognostic information for impending failures and remaining useful life is essential to inform decision-making by enabling cost versus risk estimates of maintenance actions. These estimates are generally provided by physics-based or data-driven models developed on historical information. Although current models provide some predictive capabilities, the ability to represent individualized dynamic factors that affect system health is limited. To address these shortcomings, we examine the biological phenomenon of epigenetics. Epigenetics provides insight into how environmental factors affect genetic expression in an organism, providing system health information that can be useful for predictions of future state. The means by which environmental factors influence epigenetic modifications leading to observable traits can be correlated to circumstances affecting system health. In this paper, we investigate the general parallels between the biological effects of epigenetic changes on cellular DNA to the influences leading to either system degradation and compromise, or improved system health. We also review a variety of epigenetic computational models and concepts, and present a general modeling framework to support adaptive system prognostics.

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Burnett, Margaret M. Information Foraging Theory in Software Maintenance. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada579505.

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Gootwine, Elisha, Warren C. Foote, Moshe Shani, and H. Goot. Genetic Improvement of Sheep by Introduction of Foreign Genetic Information into Prolific Breeds. United States Department of Agriculture, August 1985. http://dx.doi.org/10.32747/1985.7566578.bard.

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Broccoli, Dominique. Telomerase Independent Telomere Maintenance in Ovarian Cancer: A Molecular Genetic Analysis. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada407268.

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Brandt, Craig M., Johnnie H. Jernigan, and Ronald J. Dierker. Integrated Maintenance Information System: Training Technology Scenarios. Fort Belvoir, VA: Defense Technical Information Center, October 1987. http://dx.doi.org/10.21236/ada187960.

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Halsey, P., M. Busbee, L. Miller, J. Wills, and S. Woods. Naval Aviation Maintenance Office Information Strategy Plan. Office of Scientific and Technical Information (OSTI), June 1990. http://dx.doi.org/10.2172/6874872.

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Elrod, M., P. Green, W. Pennewell, and S. Ruple. Reliability-centered maintenance information system conceptual model. Office of Scientific and Technical Information (OSTI), July 1990. http://dx.doi.org/10.2172/6618157.

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Smillie, R. J. Improving Maintenance Performance: Design Strategies for Technical Information. Fort Belvoir, VA: Defense Technical Information Center, May 1991. http://dx.doi.org/10.21236/ada237016.

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Cooke, Garth, Nicola Maiorana, Theodore Myers, Johnnie Jernigan, and Eric N. Carlson. Integrated Maintenance Information System Diagnostic Module (IMIS-DM). Version 5.0. Fort Belvoir, VA: Defense Technical Information Center, June 1991. http://dx.doi.org/10.21236/ada237244.

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