Добірка наукової літератури з теми "M-cycle"

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Статті в журналах з теми "M-cycle"

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Bryant, Darryn E., C. A. Rodger, and Erin R. Spicer. "Embeddings of m-cycle systems and incomplete m-cycle systems: m ⩽ 14." Discrete Mathematics 171, no. 1-3 (June 1997): 55–75. http://dx.doi.org/10.1016/s0012-365x(96)00072-6.

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Bryant, Darryn E., A. Khodkar, and Hung-Lin Fu. "(m,n)-cycle systems." Journal of Statistical Planning and Inference 74, no. 2 (November 1998): 365–70. http://dx.doi.org/10.1016/s0378-3758(98)00084-6.

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Hean, Sarah, Sarah Cowley, Angus Forbes, Peter Griffiths, and Jill Maben. "The M–C–M′ cycle and social capital." Social Science & Medicine 56, no. 5 (March 2003): 1061–72. http://dx.doi.org/10.1016/s0277-9536(02)00103-x.

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Liang, Zhihe, Hung-Lin Fu, and Wentao Wang. "On m-cycle holey systems." Journal of Discrete Mathematical Sciences and Cryptography 20, no. 8 (November 17, 2017): 1637–49. http://dx.doi.org/10.1080/09720529.2016.1160511.

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Lindner, C. C., and C. A. Rodger. "2-perfect m-cycle systems." Discrete Mathematics 104, no. 1 (June 1992): 83–90. http://dx.doi.org/10.1016/0012-365x(92)90626-q.

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Brain, James L. ": The Human Cycle . Colin M. Turnbull." American Anthropologist 87, no. 4 (December 1985): 933–34. http://dx.doi.org/10.1525/aa.1985.87.4.02a00310.

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Adams, Peter, and Darryn E. Bryant. "i-perfectm-cycle systems,m ≤ 19." Aequationes Mathematicae 53, no. 1-2 (February 1997): 275–94. http://dx.doi.org/10.1007/bf02215976.

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Adams, Peter, and Darryn E. Bryant. "i-perfectm-cycle systems,m ≤ 19." Aequationes Mathematicae 52, no. 1 (February 1996): 319. http://dx.doi.org/10.1007/bf01818349.

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MATSUI, Kohei, and Takahiko MIYAZAKI. "Performance improvement of inverted Brayton cycles by application of M-cycle." Proceedings of the National Symposium on Power and Energy Systems 2019.24 (2019): E131. http://dx.doi.org/10.1299/jsmepes.2019.24.e131.

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Wu, Shung-Liang, and Hung-Lin Fu. "A Note on Cyclic m-cycle Systems of Kr(m)." Graphs and Combinatorics 22, no. 3 (November 2006): 427–32. http://dx.doi.org/10.1007/s00373-006-0658-z.

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Дисертації з теми "M-cycle"

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Leão, Maria João de Lemos Pinto Estrela. "Modulation of G2/M cell cycle checkpoints by Epstein-Barr virus." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414473.

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Blakemore, Louise Margaret. "Curcumin-induced G2/M cell cycle arrest in colorectal cancer cells." Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/9809.

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Curcumin, a diet-derived chemopreventive and chemotherapeutic agent has been shown to induce G2/M cell cycle arrest, and previous studies suggested that microtubule depolymerisation may be linked to M-phase arrest. However, mechanisms involved have not been elucidated and often non-physiological concentrations of curcumin were used. The goal of this study was to characterise in more detail curcumin-induced cell cycle arrest using a panel of human colorectal cancer cell (CRC) lines, HT-29, SW480, HCT116 p53+/+, HCT116 p53-/- and HCT116 p21-/-. Using physiologically relevant concentrations of curcumin (5-10μM), achievable in the gut tissue following oral ingestion, cell cycle analysis showed that treatment for 12 hours results in significant G2/M arrest in all five cell lines. Curcumin treatment significantly increased the number of cells in M phase in 4 out of the 5 lines tested for this duration, and those with microsatellite instability (HCT116) were found to have a higher mitotic index than those with chromosomal instability. Pre-treatment with caffeine abrogated mitotic arrest in these cell lines, indicating the involvement of the ATM/ATR kinases. Activating phosphorylation of the Chk1 kinase was increased and total protein levels of CDC25C reduced, further implicating the DNA damage pathway in the induction of arrest. Higher levels of HSP70 were also found, indicating proteotoxic stress such as proteasomal inhibition. Image analysis revealed impaired mitotic progression, and significantly higher levels of mitotic spindle abnormalities following curcumin treatment. Aurora B mislocalisation and significantly lower levels of centrosomal separation were found in the HCT116 p53+/+ line. Furthermore, the high levels of pH2A.X staining seen in curcumin-treated mitotic but not interphase cells suggest that aberrant mitosis may result in DNA damage. This proteotoxic and genotoxic stress incurred following curcumin treatment may contribute to the upregulation of NKG2D ligands on the cell surface, leading to CRC lysis and enhancement of the anti-cancer immune response.
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Quinn, Jennifer E. "BRCA1 mediated G2/M cell cycle arrest in response to taxol." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326034.

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Winks, Joanna Shaw. "Agonist-induced inhibition of the m-current : involvement of the phosphoinositide cycle." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405561.

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Hirabayashi, Shigeki. "APOBEC3B is preferentially expressed at the G2/M phase of cell cycle." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264663.

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Анотація:
京都大学
新制・課程博士
博士(医学)
甲第23382号
医博第4751号
新制||医||1052(附属図書館)
京都大学大学院医学研究科医学専攻
(主査)教授 伊藤 貴浩, 教授 滝田 順子, 教授 江藤 浩之
学位規則第4条第1項該当
Doctor of Medical Science
Kyoto University
DFAM
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El, Dika Mohammed. "Régulation de la phase M du cycle cellulaire par CDK1, PP2A et CDC6." Thesis, Rennes 1, 2013. http://www.theses.fr/2013REN1S068.

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L'objectif de cette thèse est de mieux comprendre la régulation de la phase M du cycle cellulaire. Nos expériences ont été effectuées dans des extraits acellulaires d’embryons de Xenopus laevis. Tout d'abord, nous montrons que le moment de l'entrée en phase M est précisément déterminé par un équilibre entre l'activité de la protéine kinase CDK1 et l’activité d’une protéine phosphatase sensible à l'acide okadaïque, PP2A. Nous montrons également le rôle de la protéine CDC6 dans la régulation de l'entrée dans la première phase M embryonnaire. En effet, CDC6 inhibe CDK1 et à travers cette action régule la dynamique de cette kinase lors de l'entrée et de la progression en phase M. Ces résultats mettent en évidence un nouveau contrôle qui précise le moment du clivage embryonnaire. Ce contrôle joue un rôle clé dans la coordination entre les mécanismes de régulation du cycle cellulaire et le programme de développement de l'embryon
The aim of this thesis is to understand better the regulation of the M-phase of the cell cycle. Experiments were done in cell-free extracts of Xenopus laevis one-cell embryos. Firstly, we show that the timing of the M-phase entry is precisely determined by a balance between the activity of CDK1 kinase and okadaic acid sensitive phosphatase, mainly PP2A. Secondly, we show the role of CDC6 protein in regulation of the entry into the first embryonic M-phase. CDC6 inhibits CDK1 and through this action regulates the dynamic of this kinase upon M-phase entry and during M-phase progression. This mechanism discovered during my PhD allows controlling precisely the timing of embryonic cleavage. This control plays a key role in coordinating the cell cycle regulating machinery and the development program of the embryo
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Lorca, Thierry. "Mécanisme de sortie de la phase M du cycle cellulaire : inactivation de la kinase cdc2." Montpellier 1, 1993. http://www.theses.fr/1993MON1T004.

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Costa, Marylia Gabriella Silva [UNESP]. "Resistência de nogueira-macadâmia (Macadamia integrifolia Maiden e Betche) aos nematoides-das-galhas." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/154207.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A nogueira-macadâmia pertence à família Proteaceae e é originária da Austrália. Sua noz é considerada a mais saborosa entre as nozes comercializadas. No Brasil, nos últimos anos, há uma expansão da macadamicultura e de seu plantio em cafezais. Além da sua consorciação com o cafeeiro, a macadâmia é uma opção de plantio em consórcio com outras culturas de ciclo curto e alternativa para o plantio em novas áreas. Embora haja um aumento da área plantada de macadâmia, as informações sobre danos causados por nematoides nessa cultura são escassas. Principalmente, aos nematoides-das-galhas, onde com frequência, as populações desses patógenos são altas em áreas cultivadas com café. No Brasil, a produção de mudas de macadâmia se dá quase que exclusivamente pelo método de enxertia, tendo como principal porta-enxerto a variedade 10-14 (Aloha). Portanto, o objetivo do trabalho foi avaliar a resistência da variedade 10-14 (Aloha) e das cultivares HAES344, HAES-660, HAES 816, IAC 4-12B, IAC 9-20 e IAC 4-20 a Meloidogyne incognita raça 2, M. paranaensis, M. exigua, M. enterolobii e M. javanica, além de estudar o ciclo de vida dos nematoides-das-galhas na variedade 10-14 (Aloha) por ser a mais utilizada como porta-enxerto na produção de mudas. O substrato de cada parcela foi infestado com aproximadamente 5.000 ovos e eventuais juvenis dos nematoides estudados, separadamente, provenientes de populações puras, processadas segundo o método proposto por Hussey e Barker. Tomateiros ‘Rutgers’ foram utilizados como padrão de viabilidade do inóculo de M. incognita raça 2, de M. enterolobii e de M. javanica, plantas de café ‘Mundo Novo’ foram utilizadas para atestar a viabilidade de M. paranaensis e M. exigua. O delineamento experimental utilizado foi inteiramente ao acaso, com cinco repetições. As avaliações foram feitas aos 120 dias após a inoculação. Os índices de galhas (IG) e índices de massas de ovos (IMO) foram obtidos de acordo com a escala de notas proposta por Taylor e Sasser. Para a obtenção do fator de reprodução (FR=PF/PI), os sistemas radiculares foram processados separadamente de acordo com o método de Coolen e D’Herde. Os experimentos para a avaliação do ciclo de vida das espécies de Meloidogyne foram montados em câmaras incubadoras (BOD) sob temperatura e fotoperíodo controlados. As plântulas de macadâmia, após a germinação, foram transplantadas para copos de 210 mL com substrato autoclavado. Para a obtenção do juvenil de segundo estágio (J2), os nematoides foram processados separadamente de acordo com a técnica proposta por Hussey e Barker, em seguida, as suspensões de cada espécie do nematoide foram colocadas em aparatos de Baermanns modificados para recipiente raso. Cinco dias após o transplante, cada plântula foi inoculada com 300 (J2) de M. incognita, M. paranaensis, M. exígua, M. enterolobii ou M. javanica. As avaliações foram aos 5, 15, 25 e 35 dias após a inoculação (DAI). Os sistemas radiculares das plantas foram lavados e coloridos com fucsina ácida para a classificação dos estádios de desenvolvimento do nematoide. Os resultados mostraram que todas as cultivares e a variedade 10-14 (Aloha) de macadâmia foram resistentes aos nematoides estudados, demostrando a resistência. Os nematoides não completaram o ciclo de vida na variedade 10-14 (Aloha), podendo ser utilizada como porta-enxerto na produção de mudas.
The macadamia nut belongs to the Proteaceae family, is originally from Australia, and is considered one of the most flavorful nuts in the market. In Brazil, macadamia nuts have been increasingly planted alongside coffee. In addition to its consortium with this crop, macadamia can also be planted alongside other short cycle cultures, and is also an alternative to planting in new areas. Although an increase in planted macadamia areas has been observed, information on nematode damage to this crop is scarce, mainly regarding root-knot nematodes, which are frequently observed in high populations in coffee crop areas. In Brazil, the production of macadamia seedlings occurs almost exclusively by the grafting method, with the 10-14 (Aloha) variety as the rootstock. In this context, the aim of this research was to evaluate the resistance of macadamia variety 10-14 (Aloha) and macadamia cultivars, HAES-344, HAES-660, HAES 816, IAC 4-12B, IAC 9-20 and IAC 4-20 to Meloidogyne incognita race 2, M. paranaensis, M. exigua, M. enterolobii and M. javanica, and to study the life cycle of root-knot nematodes in the variety 10-14 (Aloha), as it is the most frequent rootstock for seedling production. The substrate of each plot was infested with approximately 5,000 nematode eggs, separately, from pure populations processed according to the Hussey and Barker method. 'Rutgers' tomatoes were used as the viability standard for the M. incognita race 2, M. enterolobii and M. javanica inocula. 'Mundo Novo' coffee plants were used to confirm M. paranaensis and M. exigua viability. The experimental design was completely randomized, with five replications and the evaluations were carried out at 120 days after inoculation. The Gall index (GI) and egg mass index (EMI) were obtained according to the scale proposed by Taylor and Sasser. To calculate the reproduction factor (RF = PF/PI), the root systems were processed separately according to the Coolen and D'Herde method. The experiments carried out for the Meloidogyne species life cycle evaluation were mounted in incubators (BOD) under controlled temperature and photoperiod. After germination, Macadamia seedlings were transplanted into 210 mL bowls with autoclaved substrate. To obtain the juvenile second stage (J2), the nematodes were processed separately according to the technique proposed by Hussey and Barker. Suspensions of each nematode species were placed in a Baermanns apparatus, modified to a shallow container. Five days after transplantation, each seedling was inoculated with 300 (J2) M. incognita, M. paranaensis, M. exigua, M. enterolobii or M. javanica. Evaluations were carried out at 5, 15, 25 and 35 days post-inoculation (DPI). The plant root systems were washed and stained with acid fuchsin for nematode development stage classification. The results indicate that all macadamia cultivars and variety 10-14 (Aloha) were resistant to the studied nematodes, demonstrating resistance. The nematodes did not complete their life cycle on the 10-14 (Aloha) variety, indicating that it may be used as the rootstock for seedlings.
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Montanez-Wiscovich, Marjorie E. "Discerning the Role of LMO4 as a Global Modulator of G2/M Cell Cycle Progression and Centrosome Cycle in Breast Cancer Cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1259899890.

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Cervigni, Romina Ines. "Analysis of the molecular mechanisms of the Golgi-based G2/M cell cycle checkpoint." Thesis, Open University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580685.

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This thesis is focused on the role of Golgi fragmentation in the regulation of the G2/M transition of the cell cycle, and it is based on previous findings that Golgi fragmentation is required to enter into mitosis. The Golgi complex is composed of many cisternal stacks that are interconnected by tubules, to form a continuous 'ribbon-like' structure. During mitosis, the Golgi ribbon undergoes extensive fragmentation through a multi stage process that promotes its correct partitioning and inheritance by the daughter cells. The first part of my work is focused on the understanding of the mechanisms which block cells in G2 when Golgi fragmentation is inhibited. I show that the Golgi-dependent G2 arrest is mediated by a failure of centrosome maturation, an event that is essential to achieve activation of the CdkllCyclinB (Cdkl/CycB) complex, the master regulator of mitosis. Indeed, the failure of Golgi fragmentation inhibits the recruitment to and activation at the centrosome of the kinase Aurora-A. This kinase is essential for the activation of Cdkl/CycB at the centrosome. This part of the thesis contributes to the definition of a previously unidentified point of dialogue between the Golgi apparatus and the centrosome in the regulation of G2/M transition. The second part of the thesis describes the development of three novel experimental approaches to induce the block of Golgi fragmentation. They integrate a previously developed assay that is based on the microinjection of blockers of Golgi fragmentation, a reliable but demanding approach. The assays that I have developed are based on the ability of the GRASP65 protein to regulate Golgi fragmentation. As well as being essential for inducing the Golgi checkpoint in a wide cell population, they are also useful for the unravelling of the mechanism through which GRASP65 acts in the Golgi checkpoint.
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Книги з теми "M-cycle"

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Mead, Kenneth M. Pipeline safety risk assessment program could help evaluate inspection cycle: Statement of Kenneth M. Mead, Director, Transportation Issues, Resources, Community, and Economic Development Division before the Subcommittee on Transportation and Related Agencies, House Committee on Appropriations. [Washington, D.C.?]: U.S. General Accounting Office, 1989.

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Bussone, Guillaume. Méthodologie & révisions transversales. Paris: Ellipses, 2003.

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Bmw M/Cycle (Classic Motorcycles). Osprey Publishing (UK), 1993.

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Éducation physique: Cycle primaire, M-3e. [Ottawa]: Ottawa Board of Education, 1990.

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Harrison, M. John. Cycle de Viriconium by Harrison, M. John (Michael John). Non Renseigné, 1985.

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Clute, Paul. Regulation of an M-phase cell-cycle checkpoint in Xenopus laevis embryos. 1996.

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C, Laet. Agenda Semainier 2020 M&a - Spécial Cycle Féminin: Le Premier Agenda Créé Pour Planifier et S'Organiser en Fonction du Cycle Féminin. Independently Published, 2019.

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C, Laet. Agenda Semainier 2020 M&a - Spécial Cycle Féminin: Le Premier Agenda Créé Pour Planifier et S'Organiser en Fonction du Cycle Féminin. Independently Published, 2019.

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C, Laet. Agenda Semainier 2020 M&a - Spécial Cycle Féminin: Le Premier Agenda Créé Pour Planifier et Organiser en Fonction du Cycle Féminin. Independently Published, 2019.

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C, Laet. Agenda Semainier M&a Azur - Spécial Cycle Féminin: Version Académique Septembre à Août - Format Médium. Independently Published, 2020.

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Частини книг з теми "M-cycle"

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Zámborszky, Judit. "Cell Cycle Transitions, G2/M." In Encyclopedia of Systems Biology, 329–33. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_38.

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Moriya, Kentaro, and Takashi Nodera. "New Adaptive GMRES(m) Method with Choosing Suitable Restart Cycle m." In Parallel Processing and Applied Mathematics, 1105–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-24669-5_143.

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Vinckx, Luc, and Huw Davies. "Courses of Action for Improving the Safety of the Powered Cycle." In Small Electric Vehicles, 17–27. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65843-4_2.

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AbstractThis paper explores the possibility to include a number of safety features from passenger cars in powered cycles with three or four wheels, whilst complying with the legal definitions and requirements, and also the legal conditions to use the bicycle lanes. The differences between technical specifications contained within EU law for pedal cycle with pedal assistance, powered cycles, quadricycles and passenger cars will be explained. Further, examples of traffic code rules with respect to the use of bicycle lanes in different countries will be discussed. Finally, the need for new safety criteria for powered cycles, replacing the existing power limit, is highlighted. In addition to the above, the need for a different technical approach to deal with the stability of 1 m wide e-bikes with a vehicle height similar to a mainstream passenger car will be discussed.
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Gaur, Hari S. "Management of root-knot nematodes in rice." In Integrated nematode management: state-of-the-art and visions for the future, 55–60. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247541.0008.

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Abstract This chapter deals with the expanding problem caused by the root knot nematodes Meloidogyne graminicola, M. hainanensis, M. lini, M. incognita, M. javanica, M. oryzae, M. salasi and M. triticoryzae that affects the rice and even wheat in commonly used rotations in India, their economic importance, host range,geographical distribution, damage symptoms, biology and life cycle, survival and dissemination, population dynamics, interaction with other nematodes and pathogens, recommended integrated nematode management systems and future outlook.
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Amaldi, Edoardo, Claudio Iuliano, Tomasz Jurkiewicz, Kurt Mehlhorn, and Romeo Rizzi. "Breaking the O(m 2 n) Barrier for Minimum Cycle Bases." In Lecture Notes in Computer Science, 301–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04128-0_28.

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Carneiro, Regina M. D. G., Marcilene F. A. Santos, and José Mauro C. Castro. "Nematodes." In Guava: botany, production and uses, 270–84. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247022.0014.

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Abstract The following review of the nematodes from cultivated guava is limited to the major problem caused by M. enterolobii, its idenfication and its management strategies. The synonymization of Meloidogyne enterolobii with Meloidogyne mayaguensis and the different methods of identifying Meloidogyne species are discussed. The life cycle, host-parasite relationships, symptoms, damage and dissemination of M. enterolobii are described. The host status of cover crops, maize and fruit plants for M. enterolobii is discussed, as well as the resistance in Psidium spp. to root-knot nematodes. New prospects using genetic resistance in Brazil and some control strategies that can be used in an integrated way are presented.
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Visser, Johnny, and Wim M. L. Wesemael. "Integrated management of Meloidogyne chitwoodi and M. fallax in potato: a complicated agronomical puzzle in the Netherlands and Belgium." In Integrated nematode management: state-of-the-art and visions for the future, 347–53. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247541.0048.

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Abstract Meloidogyne chitwoodi and M. fallax have been important nematode problems in arable farming in the Netherlands and Belgium ever since their detection in the 1980s. Their quarantine status and the damage inflicted on product quality in important cash crops such as potato, carrots, black salsify and gladiolus has increased drastically the need for integrated nematode management strategies that prevent yield losses and further spreading. This chapter elaborates on the economic importance, host range, distribution, symptoms of damage, biology and life cycle, interactions with other nematodes and pathogens, recommended integrated nematode management (prevention, inventory, crop rotation and supporting measures), and management optimization of M. chitwoodi and M. fallax. Future research requirements are also mentioned.
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Liu, Hai Yan, Hui Ping Tang, Cheng Li, Yuan Ping Huang, Boyun Huang, and Yong Liu. "Low-Cycle Fatigue Performances of P/M Ti-Fe-Mo-Al-Nd Alloy." In Progress in Powder Metallurgy, 973–76. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-419-7.973.

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9

Fourie, Hendrika. "Maize and root-knot nematodes: a problematic, deep-seated association." In Integrated nematode management: state-of-the-art and visions for the future, 41–47. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247541.0006.

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Abstract This paper focuses on the economic importance, host range, geographical distribution, damage symptoms and biology and life cycle of the root knot nematodes Meloidogyne incognita and M. javanica infesting maize in South Africa. Information on their interactions with other nematodes and pathogens, recommended integrated nematode management strategies and future research requirements are also discussed.
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Soares, Pedro Luiz Martins, and Daniel Dalvan Nascimento. "Integrated nematode management of root lesion and root-knot nematodes in soybean in Brazil." In Integrated nematode management: state-of-the-art and visions for the future, 103–10. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247541.0015.

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Abstract This chapter focuses on the economic importance, host range, geographical distribution, damage symptoms and biology and life cycle of root lesion and root-knot nematodes infesting soyabean in Brazil, i.e. Pratylenchus brachyurus, Meloidogyne javanica and M. incognita. Some information on their interactions with other nematodes and pathogens, efficacy and optimization of some recommended integrated nematode management strategies and future outlook and research requirements for nematode management are also presented.
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Тези доповідей конференцій з теми "M-cycle"

1

Kashif, Muhammad, Takahiko Miyazaki, Muhammad Sultan, Zahid Mahmood Khan, and Muhammad H. Mahmood. "Investigation of Maisotsenko Cycle (M-cycle) Air-Conditioning System for Multan(Pakistan)." In 2017 International Conference on Energy Conservation and Efficiency (ICECE). IEEE, 2017. http://dx.doi.org/10.1109/ece.2017.8248823.

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Zhu, Yunfeng. "Hypothesis on the Cycle of Japan M=7.8 earthquake." In International Geophysical Conference, Beijing, China, 24-27 April 2018. Society of Exploration Geophysicists and Chinese Petroleum Society, 2018. http://dx.doi.org/10.1190/igc2018-173.

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Goodrich, Robert W., and Shui Hung Kwok. "Duty cycle metrics system for the W. M. Keck Observatory." In SPIE Astronomical Telescopes + Instrumentation, edited by Roger J. Brissenden and David R. Silva. SPIE, 2008. http://dx.doi.org/10.1117/12.789718.

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Bold, B. S. "Innovative process architectures for rapid cycle-time sub 0.5 m CMOS." In IEE Colloquium on Advanced MOS and Bi-Polar Devices. IEE, 1995. http://dx.doi.org/10.1049/ic:19950192.

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Legare, Francois, Bruno E. Schmidt, Andrew D. Shiner, Philippe Lassonde, David M. Villeneuve, Paul B. Corkum, and Jean-Claude Kieffer. "Millijoule-level CEP stable 1.8 µm 1.6 cycle laser pulses." In 12th European Quantum Electronics Conference CLEO EUROPE/EQEC. IEEE, 2011. http://dx.doi.org/10.1109/cleoe.2011.5943049.

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6

Yi, Maoxiang, Xiaohong Liu, Qingwu Wu, Tianming Ni, Zhengfeng Huang, and Huaguo Liang. "NBTI mitigation by M-IVC with input duty cycle and randomness constraints." In 2016 IEEE East-West Design & Test Symposium (EWDTS). IEEE, 2016. http://dx.doi.org/10.1109/ewdts.2016.7807666.

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7

Schelasin, Roland E. A. "Estimating wafer processing cycle time using an improved G/G/M queue." In 2013 Winter Simulation Conference - (WSC 2013). IEEE, 2013. http://dx.doi.org/10.1109/wsc.2013.6721738.

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8

Praticò, Filippo G., Domenico Tramontana, Antonio Casciano, and Antonella Attinà. "Geosynthetics and Pavement Life Cycle: An Analysis through the M-E PDG." In GeoShanghai International Conference 2010. Reston, VA: American Society of Civil Engineers, 2010. http://dx.doi.org/10.1061/41108(381)40.

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9

Xu, Minli, Youming Zhang, Xusheng Tang, Junjie Li та Fengyi Huang. "A 25% Duty -Cycle Clock Generation Circuit in 0.13 μ m CMOS". У 2022 7th International Conference on Integrated Circuits and Microsystems (ICICM). IEEE, 2022. http://dx.doi.org/10.1109/icicm56102.2022.10011355.

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Maisotsenko, Valeriy, and Ilya Reyzin. "The Maisotsenko Cycle for Electronics Cooling." In ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems collocated with the ASME 2005 Heat Transfer Summer Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/ipack2005-73283.

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The Maisotsenko Cycle (M-Cycle) combines heat exchange and evaporative cooling [1–3] in an effective indirect evaporative cooling process resulting in product flow temperature approaching incoming air dew point (not wet bulb) temperature. Thermodynamically, the M-Cycle is based on air precooling before passing through the heat rejection water evaporating area, so the difference between the enthalpy of the air at its dew point temperature and the same air saturated at a higher temperature is used to provide cooling capacity to reject the heat, for example from the electronics. Today Delphi Corp and Coolerado Inc. are working on producing M-Cycle based heat- and mass exchangers for the Coolerado Coolers™ used in air conditioning. Other market applications, including electronics cooling, are being considered as well. A broad range of the cooling capacity (for example, from 10 W to 50 kW and more) could be obtained from the coolers utilizing M-Cycle. Due to superior thermodynamic process, M-Cycle based air coolers have a very high Energy Efficiency Ratio (EER). As per National Renewable Energy Laboratory (NREL), the average cooling capacity of Coolerado Coolers™ have EER more than 45; relatively to EER equal 13 for the best conventional air coolers. The M-cycle is much more efficient than any other heat rejection/recovery cycle, and the Coolerado Cooler™, as a single air cooling device has better specific characteristics (cooling capacity, air pressure drop, power consumption, etc.) than any existing coolers. Unlike traditional vapor compression, absorption, or thermoelectric refrigeration systems, where increase of air inlet temperature dramatically reduces cooling capacity, the M-Cycle based unit cooling capacity goes up with air inlet temperature rise. M-cycle based device similar to Coolerado Cooler™ can also cool any fluid to the temperature approaching the dew point temperature of incoming air without using compressor and refrigerant. That can revolutionize the electronics cooling market. The Coolerado Cooler was recognized by the prestigious R&D 100 Awards program as one of 2004’s most technologically significant products introduced to the world.
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Звіти організацій з теми "M-cycle"

1

Fulco, Charles S., K. W. Kambis, A. L. Friedlander, P. B. Rock, and J. E. Staab. Carbohydrate Supplementation Improves Time-Trial Cycle Performance at 4300 m Altitude. Fort Belvoir, VA: Defense Technical Information Center, February 2003. http://dx.doi.org/10.21236/ada411927.

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2

Davis, Shelly M., and Shigeki Miyamoto. Exploring a Link Between NF-KB and G2/M Cell Cycle Arrest in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada436875.

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3

Davis, Shelly M. Exploring a Link Between NF-kappaB and G2/M Cell Cycle Arrest in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, April 2004. http://dx.doi.org/10.21236/ada425730.

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4

Grafi, Gideon, and Brian Larkins. Endoreduplication in Maize Endosperm: An Approach for Increasing Crop Productivity. United States Department of Agriculture, September 2000. http://dx.doi.org/10.32747/2000.7575285.bard.

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The focus of this research project is to investigate the role of endoreduplication in maize endosperm development and the extent to which this process contributes to high levels of starch and storage protein synthesis. Although endoreduplication has been widely observed in many cells and tissues, especially those with high levels of metabolic activity, the molecular mechanisms through which the cell cycle is altered to produce consecutive cycles of S-phase without an intervening M-phase are unknown. Our previous research has shown that changes in the expression of several cell cycle regulatory genes coincide with the onset of endoreduplication. During this process, there is a sharp reduction in the activity of the mitotic cyclin-dependent kinase (CDK) and activation of the S-phase CDK. It appears the M-phase CDK is stable, but its activity is blocked by a proteinaceous inhibitor. Coincidentally, the S-phase checkpoint protein, retinoblastoma (ZmRb), becomes phosphorylated, presumably releasing an E2F-type transcriptional regulator which promotes the expression of genes responsible for DNA synthesis. To investigate the role of these cell cycle proteins in endoreduplication, we have created transgenic maize plants that express various genes in an endosperm-specific manner using a storage protein (g-zein) promoter. During the first year of the grant, we constructed point mutations of the maize M-phase kinase, p34cdc2. One alteration replaced aspartic acid at position 146 with asparagine (p3630-CdcD146N), while another changed threonine 161 to alanine (p3630-CdcT161A). These mutations abolish the activity of the CDK. We hypothesized that expression of the mutant forms of p34cdc2 in endoreduplicating endosperm, compared to a control p34cdc2, would lead to extra cycles of DNA synthesis. We also fused the gene encoding the regulatory subunit of the M- phase kinase, cyclin B, under the g-zein promoter. Normally, cyclin B is expected to be destroyed prior to the onset of endoreduplication. By producing high levels of this protein in developing endosperm, we hypothesized that the M-phase would be extended, potentially reducing the number of cycles of endoreduplication. Finally, we genetically engineered the wheat dwarf virus RepA protein for endosperm-specific expression. RepA binds to the maize retinoblastoma protein and presumably releases E2F-like transcription factors that activate DNA synthesis. We anticipated that inactivation of ZmRb by RepA would lead to additional cycles of DNA synthesis.
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Kim, Changmo, Ghazan Khan, Brent Nguyen, and Emily L. Hoang. Development of a Statistical Model to Predict Materials’ Unit Prices for Future Maintenance and Rehabilitation in Highway Life Cycle Cost Analysis. Mineta Transportation Institute, December 2020. http://dx.doi.org/10.31979/mti.2020.1806.

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The main objectives of this study are to investigate the trends in primary pavement materials’ unit price over time and to develop statistical models and guidelines for using predictive unit prices of pavement materials instead of uniform unit prices in life cycle cost analysis (LCCA) for future maintenance and rehabilitation (M&R) projects. Various socio-economic data were collected for the past 20 years (1997–2018) in California, including oil price, population, government expenditure in transportation, vehicle registration, and other key variables, in order to identify factors affecting pavement materials’ unit price. Additionally, the unit price records of the popular pavement materials were categorized by project size (small, medium, large, and extra-large). The critical variables were chosen after identifying their correlations, and the future values of each variable were predicted through time-series analysis. Multiple regression models using selected socio-economic variables were developed to predict the future values of pavement materials’ unit price. A case study was used to compare the results between the uniform unit prices in the current LCCA procedures and the unit prices predicted in this study. In LCCA, long-term prediction involves uncertainties due to unexpected economic trends and industrial demand and supply conditions. Economic recessions and a global pandemic are examples of unexpected events which can have a significant influence on variations in material unit prices and project costs. Nevertheless, the data-driven scientific approach as described in this research reduces risk caused by such uncertainties and enables reasonable predictions for the future. The statistical models developed to predict the future unit prices of the pavement materials through this research can be implemented to enhance the current LCCA procedure and predict more realistic unit prices and project costs for the future M&R activities, thus promoting the most cost-effective alternative in LCCA.
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Waisel, Yoav, Bobbie McMichael, and Amram Eshel. Decision Making within Plant Root Systems. United States Department of Agriculture, March 1996. http://dx.doi.org/10.32747/1996.7613030.bard.

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Architecture of a root system is the expression of the potential of various root types to branch, to grow and to coordinate with other plant organs, under the specific limitations of the environmental conditions. The present investigation has proven the following points. 1) Genotypes with different types of root systems were identified. The growth patterns of their roots and the distribution of laterals along their main axes were recorded. 2) The patterns of development of the root systems of four cotton genotypes, throughout the entire life cycle of the plants, were described, even at such a late stage of development when the total length of the roots exceeded two kilometers. To the best of our knowledge, this is the first time that an analysis of this type is accomplished. 3) The development of root systems under restrictive soil conditions were compared with those that have developed under the non-restrictive conditions of aeroponics. Results indicate that in the absence of the mechanical impedance of the soil, cotton plants develop single roots that reach the length of 6 m, and have a total root length of 2000 m. Thus, root growth is strongly inhibited by the soil, with some root types being inhibited more than others. 4) One of the important decisions, in constructing an operational root system architecture of mature plants, is the shift of the balance between various root fractions in favor of the very fine roots. 5) Root system architecture is determined, in part, by the sites of initiation of the lateral roots. This is determined genetically by the number of xylem archs and by the totuosity of the stele. Selection for such traits should be sought.
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Brown Horowitz, Sigal, Eric L. Davis, and Axel Elling. Dissecting interactions between root-knot nematode effectors and lipid signaling involved in plant defense. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7598167.bard.

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Root-knot nematodes, Meloidogynespp., are extremely destructive pathogens with a cosmopolitan distribution and a host range that affects most crops. Safety and environmental concerns related to the toxicity of nematicides along with a lack of natural resistance sources threaten most crops in Israel and the U.S. This emphasizes the need to identify genes and signal mechanisms that could provide novel nematode control tactics and resistance breeding targets. The sedentary root-knot nematode (RKN) Meloidogynespp. secrete effectors in a spatial and temporal manner to interfere with and mimic multiple physiological and morphological mechanisms, leading to modifications and reprogramming of the host cells' functions, resulted in construction and maintenance of nematodes' feeding sites. For successful parasitism, many effectors act as immunomodulators, aimed to manipulate and suppress immune defense signaling triggered upon nematode invasion. Plant development and defense rely mainly on hormone regulation. Herein, a metabolomic profiling of oxylipins and hormones composition of tomato roots were performed using LC-MS/MS, indicating a fluctuation in oxylipins profile in a compatible interaction. Moreover, further attention was given to uncover the implication of WRKYs transcription factors in regulating nematode development. In addition, in order to identify genes that might interact with the lipidomic defense pathway induced by oxylipins, a RNAseq was performed by exposing M. javanicasecond-stage juveniles to tomato protoplast, 9-HOT and 13-KOD oxylipins. This transcriptome generated a total of 4682 differentially expressed genes (DEGs). Being interested in effectors, we seek for DEGs carrying a predicted secretion signal peptide. Among the DEGs including signal peptide, several had homology with known effectors in other nematode species, other unknown potentially secreted proteins may have a role as root-knot nematodes' effectors which might interact with lipid signaling. The molecular interaction of LOX proteins with the Cyst nematode effectors illustrate the nematode strategy in manipulating plant lipid signals. The function of several other effectors in manipulating plant defense signals, as well as lipids signals, weakening cell walls, attenuating feeding site function and development are still being studied in depth for several novel effectors. As direct outcome of this project, the accumulating findings will be utilized to improve our understanding of the mechanisms governing critical life-cycle phases of the parasitic M. incognita RKN, thereby facilitating design of effective controls based on perturbation of nematode behavior—without producing harmful side effects. The knowledge from this study will promote genome editing strategies aimed at developing nematode resistance in tomato and other nematode-susceptible crop species in Israel and the United States.
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Kapulnik, Yoram, Maria J. Harrison, Hinanit Koltai, and Joseph Hershenhorn. Targeting of Strigolacatones Associated Pathways for Conferring Orobanche Resistant Traits in Tomato and Medicago. United States Department of Agriculture, July 2011. http://dx.doi.org/10.32747/2011.7593399.bard.

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This proposal is focused on examination of two plant interactions: parasitic with Orobanche, and symbiosis with arbuscular mycorrhiza fungi (AMF), and the involvement of a newly define plant hormones, strigolactones (SLs), in these plant interactions. In addition to strigolactones role in regulation of above-ground plant architecture, they are also known to be secreted from roots, and to be a signal for seed germination of the parasitic plants Orobanche. Moreover, secreted strigolactones were recognized as inducers of AMFhyphae branching. The present work was aimed at Generation of RNAi mutants of both tomato and Medicago, targeting multiple genes that may be involved in strigolactone production, carotenoid biosynthesis pathway, Pi signaling or other metabolic pathways, and hence affect AMF colonization and/or Orobanche resistance. Following the newly formed and existing RNAi mutants were examined for AMF colonization and Orobanche resistance. At the first phase of this project Orobanche seed germination assays and AMF colonization were examined in intact plants. These assays were shown to be effective and resulted with enhancement of Orobanche seed germination and AMF colonization in WT tomato plants, whereas roots of strigolactones impaired lines did not result with Orobanche seed germination and mycorrhiza colonization. Unexpectedly, root organ cultures (ROC) that were produced from the same wild type (WT) and mutant lines did not induce the Orobanche seed germination and AMFhyphal branching. This implies that under in vitro conditions ROC cultures are missing an important component for induction of Orobanche seed germination and AMFhyphal branching. In another line of experiments we have tested transgenic lines of Medicagotruncatula for AMFhuyphal branching and Orobanche seed germination assays. These lines included lines silenced for a GRAS transcription factor (RNAi 1845), an NBS-LRR type resistance gene (RNAi 1847), a kinase (RNAi 2403) and a protein of unknown function (RNAi 2417). In all cases, five independent transgenic root lines showed altered AMFphenotypes with reduced or aberrant colonization patterns. Following, we transformed tomato plants with the M. truncatulaTC 127050 PhosphoinositidekinaseRNAi construct. Transgenic lines that contained GUS constructs were used as control. All transgenic lines showed reduced level of Orobanche seed germination, masking any strigoalctones-specific effect. The research demonstrated that SLs production may not be examined in ROC –based bioassays. It was shown by the 3 independent assays employed in this project that none of the recognized characters of SLs may be reflected in these bioassays. However, when the whole plant root exudates were examined, SLs activity in root exudates was demonstrated. Hence, it can be concluded that the presence of an intact shoot, and possibly, shoot factors, may be necessary for production of SLs in roots. Another point of interest that rises from these results is that the presence of SLs is not necessary for AMF completion of life cycle. Hence, it may be concluded that SLs are important for AMFhyphal branching, before symbiosis, but not essential for AMF colonization and life cycle completion under ROC system conditions.
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Samach, Alon, Douglas Cook, and Jaime Kigel. Molecular mechanisms of plant reproductive adaptation to aridity gradients. United States Department of Agriculture, January 2008. http://dx.doi.org/10.32747/2008.7696513.bard.

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Annual plants have developed a range of different mechanisms to avoid flowering (exposure of reproductive organs to the environment) under adverse environmental conditions. Seasonal environmental events such as gradual changes in day length and temperature affect the timing of transition to flowering in many annual and perennial plants. Research in Arabidopsis and additional species suggest that some environmental signals converge on transcriptional regulation of common floral integrators such as FLOWERING LOCUS T (FT). Here we studied environmental induction of flowering in the model legume Medicago truncatula. Similarly to Arabidopsis, the transition to flowering in M. truncatula is hastened by long photoperiods and long periods of vernalization (4°C for 2-3 weeks). Ecotypes collected in Israel retain a vernalization response even though winter temperatures are way above 4°C. Here we show that this species is also highly responsive (flowers earlier) to mild ambient temperatures up to 19°C simulating winter conditions in its natural habitat. Physiological experiments allowed us to time the transition to flowering due to low temperatures, and to compare it to vernalization. We have made use of natural variation, and induced mutants to identify key genes involved in this process, and we provide here data suggesting that an FT gene in M.truncatula is transcriptionally regulated by different environmental cues. Flowering time was found to be correlated with MtFTA and MtFTB expression levels. Mutation in the MtFTA gene showed a late flowering phenotype, while over-expressing MtFTA in Arabidopsis complemented the ft- phenotype. We found that combination of 4°C and 12°C resulted in a synergistic increase in MtFTB expression, while combining 4°C and long photoperiods caused a synergistic increase in MtFTA expression. These results suggest that the two vernalization temperatures work through distinct mechanisms. The early flowering kalil mutant expressed higher levels of MtFTA and not MtFTB suggesting that the KALIL protein represses MtFTA specifically. The desert ecotype Sde Boker flowers earlier in response to short treatments of 8-12oc vernalization and expresses higher levels of MtFTA. This suggests a possible mechanism this desert ecotype developed to flower as fast as possible and finish its growth cycle before the dry period. MtFTA and FT expression are induced by common environmental cues in each species, and expression is repressed under short days. Replacing FT with the MtFTA gene (including regulatory elements) caused high MtFTA expression and early flowering under short days suggesting that the mechanism used to repress flowering under short days has diversified between the two species.The circadian regulated gene, GIGANTEA (GI) encodes a unique protein in Arabidopsis that is involved in flowering mechanism. In this research we characterized how the expression of the M.truncatula GI ortholog is regulated by light and temperature in comparison to its regulation in Arabidopsis. In Arabidopsis GI was found to be involved in temperature compensation to the clock. In addition, GI was found to be involved in mediating the effect of temperature on flowering time. We tested the influence of cold temperature on the MtGI gene in M.truncatula and found correlation between MtGI levels and extended periods of 12°C treatment. MtGI elevation that was found mostly after plants were removed from the cold influence preceded the induction of MtFT expression. This data suggests that MtGI might be involved in 12°C cold perception with respect to flowering in M.truncatula. GI seems to integrate diverse environmental inputs and translates them to the proper physiological and developmental outputs, acting through several different pathways. These research enabled to correlate between temperature and circadian clock in M.truncatula and achieved a better understanding of the flowering mechanism of this species.
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10

Rosse, Anine. Stream channel monitoring for Wind Cave National Park 2021 Data report. National Park Service, January 2023. http://dx.doi.org/10.36967/2296623.

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The Northern Great Plains Inventory and Monitoring Network (NGPN) began stream channel monitoring in Highland Creek at Wind Cave National Park (WICA) in 2021. This data report summarizes the data collected during the 2021 season pertaining to watershed, reach, and physical habitat. After data are collected for at least four cycles, trends may be reported. This report covers three main areas: 1) Reporting on upland channel characteristics data that may affect habitat such as: land cover, drainage area, and total stream length; 2) Reporting of geomorphic dimensions such as: channel widths, bank angles, vegetative cover, reach slope, measures of bank stability; and 3) Determining physical habitat characteristics such as: size and distribution of bed sediment, large woody debris, and canopy cover. Indices, benchmarks, and other studies are provided in the table for informational purposes to help put Highland Creek’s measurements in context but should not be considered as a reference condition. Upland characteristics of the watershed indicate high natural land use cover (forest, grassland, and shrubland) with little development in the area. Reach characteristics include bank cover, heights, bank stability index, and vegetative cover. In addition to animal-induced erosion of the banks, bank sloughing and widening are occurring. Angles are steep, and there are some sandy banks that are unstable. When plots are revisited in three years, there will be greater understanding of the processes at play and the condition of the stream. Physical characteristics include median particle size, percentage fine substrate, geomorphic units, and canopy cover. Gravel substrate still covers much of the stream; there are wide meanders in the stream bed; and a variety of geomorphic channel units (pool, riffle, run) occur in the creek all of which are indicators of healthy habitat. While there is an absence of large woody debris and canopy cover is low, many grassland streams in good condition can have similar characteristics. More data are needed to fully assess those components and determine a suitable reference condition that can be used to later assess the status and trends of Highland Creek. The reach data contained in this report are specific to a short 150-m segment of Highland Creek and cannot be extrapolated to conditions elsewhere in the creek or to the park in general. Bank erosion and bank instability were observed along the majority of transects at site WICA SCM 001.
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