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Добірка наукової літератури з теми "L12D"

Автор: Grafiati

Опубліковано: 11 березня 2023

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Статті в журналах з теми "L12D"

O'Connor, Christopher, Philip Matsumura та Andres Campos. "The CheZ Binding Interface of CheAS Is Located in α-Helix E". Journal of Bacteriology 191, № 18 (6 липня 2009): 5845–48. http://dx.doi.org/10.1128/jb.00294-09.

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ABSTRACT Specific CheA-short (CheAS) residues, L123 and L126, were identified as critical for CheZ binding. In the CheAS ′P1-CheZ nuclear magnetic resonance structure, these residues form an interaction surface on α-helix E in the ′P1 domain. Both L123 and L126 are buried in CheA-long (CheAL), providing an explanation for why CheAL fails to bind CheZ.

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Wang, Wenjing, Xupeng Zang, Yonglun Liu, Yunyi Liang, Gengyuan Cai, Zhenfang Wu, and Zicong Li. "Dynamic miRNA Landscape Links Mammary Gland Development to the Regulation of Milk Protein Expression in Mice." Animals 12, no. 6 (March 14, 2022): 727. http://dx.doi.org/10.3390/ani12060727.

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Mammary gland morphology varies considerably between pregnancy and lactation status, e.g., virgin to pregnant and lactation to weaning. Throughout these critical developmental phases, the mammary glands undergo remodeling to accommodate changes in milk production capacity, which is positively correlated with milk protein expression. The purpose of this study was to investigate the microRNA (miRNA) expression profiles in female ICR mice’s mammary glands at the virgin stage (V), day 16 of pregnancy (P16d), day 12 of lactation (L12d), day 1 of forced weaning (FW1d), and day 3 of forced weaning (FW3d), and to identify the miRNAs regulating milk protein gene expression. During the five stages of testing, 852 known miRNAs and 179 novel miRNAs were identified in the mammary glands. Based on their expression patterns, the identified miRNAs were grouped into 12 clusters. The expression pattern of cluster 1 miRNAs was opposite to that of milk protein genes in mammary glands in all five different stages. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed that the predicted target genes of cluster 1 miRNAs were related to murine mammary gland development and lactation. Furthermore, fluorescence in situ hybridization (FISH) analysis revealed that the novel-mmu-miR424-5p, which belongs to the cluster 1 miRNAs, was expressed in murine mammary epithelial cells. The dual-luciferase reporter assay revealed that an important milk protein gene—β-casein (CSN2)—was regarded as one of the likely targets for the novel-mmu-miR424-5p. This study analyzed the expression patterns of miRNAs in murine mammary glands throughout five critical developmental stages, and discovered a novel miRNA involved in regulating the expression of CSN2. These findings contribute to an enhanced understanding of the developmental biology of mammary glands, providing guidelines for increasing lactation efficiency and milk quality.

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Ramirez, Celia, Lawrence C. Shimmin, C. Hunter Newton, Alastair T. Matheson, and Patrick P. Dennis. "Structure and evolution of the L11, L1, L10, and L12 equivalent ribosomal proteins in eubacteria, archaebacteria, and eucaryotes." Canadian Journal of Microbiology 35, no. 1 (January 1, 1989): 234–44. http://dx.doi.org/10.1139/m89-036.

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The genes corresponding to the L11, L1, L10, and L12 equivalent ribosomal proteins (L11e, L1e, L10e, and L12e) of Escherichia coli have been cloned and sequenced from two widely divergent species of archaebacteria, Halobacterium cutirubrum and Sulfolobus solfataricus, and the L10 and four different L12 genes have been cloned and sequenced from the eucaryote Saccharomyces cerevisiae. Alignments between the deduced amino acid sequences of these proteins and to other available homologous proteins of eubacteria and eucaryotes have been made. The data suggest that the archaebacteria are a distinct coherent phylogenetic group. Alignment of the proline-rich L11e proteins reveals that the N-terminal region, believed to be responsible for interaction with release factor 1, is the most highly conserved region and that there is specific conservation of most of the proline residues, which may be important in maintaining the highly elongated structure of the molecule. Although L11 is the most highly methylated protein in the E. coli ribosome, the sites of methylation are not conserved in the archaebacterial L11e proteins. The L1e proteins of eubacteria and archaebacteria show two regions of very high similarity near the center and the carboxy termini of the proteins. The L10e proteins of all kingdoms are colinear and contain approximately three fourths of an L12e protein fused to their carboxy terminus, although much of this fusion has been lost in the truncated eubacterial protein. The archaebacterial and eucaryotic L12e proteins are colinear, whereas the eubacterial protein has suffered a rearrangement through what appear to be gene fusion events. Within the L12e derived region of the L10e proteins there exists a repeated module of 26 amino acids, present in two copies in eucaryotes, three in archaebacteria, and one in eubacteria. This modular sequence is apparently also present in the L12e proteins of all kingdoms and may play a role in L12e dimerization, L10e–L12e complex formation, and the function of the L10e–L12e complex in translation.Key words: translation, ribosome.

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Stults, John T., Patrick R. Griffin, David D. Lesikar, Asha Naidu, Barbara Moffat, and Bradley J. Benson. "Lung surfactant protein SP-C from human, bovine, and canine sources contains palmityl cysteine thioester linkages." American Journal of Physiology-Lung Cellular and Molecular Physiology 262, no. 3 (March 1, 1992): 1. http://dx.doi.org/10.1152/ajplung.1992.262.3.1-a.

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Pages L118B–L125: John T. Stults, Patrick R. Griffin, David D. Lesikar, Asha Naidu, Barbara Moffat, and Bradley J. Benson. “Lung surfactant protein SP-C from human, bovine, and canine sources contains palmityl cysteine thioester linkages.” Page L124: received and accepted dates were inadvertently omitted. They should read “Received 4 October 1990; accepted in final form 11 February 1991.”

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Stults, John T., Patrick R. Griffin, David D. Lesikar, Asha Naidu, Barbara Moffat, and Bradley J. Benson. "Lung surfactant protein SP-C from human, bovine, and canine sources contains palmityl cysteine thioester linkages." American Journal of Physiology-Lung Cellular and Molecular Physiology 262, no. 6 (June 1, 1992): 1. http://dx.doi.org/10.1152/ajplung.1992.262.6.1-b.

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Shimmin, Lawrence C., C. Hunter Newton, Celia Ramirez, Janet Yee, Willa Lee Downing, Andrea Louie, Alastair T. Matheson, and Patrick P. Dennis. "Organization of genes encoding the L11, L1, L10, and L12 equivalent ribosomal proteins in eubacteria, archaebacteria, and eucaryotes." Canadian Journal of Microbiology 35, no. 1 (January 1, 1989): 164–70. http://dx.doi.org/10.1139/m89-025.

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Archaebacterial and eucaryotic cytoplasmic ribosomes contain proteins equivalent to the L11, L1, L10, and L12 proteins of the eubacterium Escherichia coli. In E. coli the genes encoding these ribosomal proteins are clustered, cotranscribed, and autogenously regulated at the level of mRNA translation. Genomic restriction fragments encoding the L11e, L1e, L10e, and L12e (equivalent) proteins from two divergent archaebacteria, Halobacterium cutirubrum and Sulfolobus solfataricus, and the L10e and L12e proteins from the eucaryote Saccharomyces cerevisiae have been cloned, sequenced, and analyzed. In the archaebacteria, as in eubacteria, the four genes are clustered and the L11e, L1e, L 10e, and L12e order is maintained. The transcription pattern of the H. cutirubrum cluster is different from the E. coli pattern and the flanking genes on either side of the tetragenic clusters in E. coli, H. cutirubrum, and Sulfolobus solfataricus are all unrelated to each other. In the eucaryote Saccharomyces cerevisiae there is a single L10e gene and four separate L12e genes that are designated L12eIA, L12eIB, L12eIIA, and L12eIIB. These five genes are not closely linked and each is transcribed as a monocistronic mRNA; the L10e, L12eIA, L12eIB, and the L12eIIA genes are contiguous and uninterrupted, whereas the L12eIIB gene is interrupted by a 301 nucleotide long intron located between codons 38 and 39.Key words: archaebacteria, ribosome, Halobacterium, Sulfolobus.

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Khanzada, Nimra, Owais Iqbal, Ambrin Baby, Sumbal Zaman, Mehvish Tofique, and Asad Rajput. "EVALUATION OF CHICKPEA GERMPLASM FOR RELATIVE RESISTANCE OR SUSCEPTIBILITY AGAINST FUSARIUM WILT AND ASCOCHYTA BLIGHT UNDER FIELD CONDITIONS." Plant Protection 6, no. 2 (August 23, 2022): 121–32. http://dx.doi.org/10.33804/pp.006.02.4234.

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Recognition and use of resistant sources against pests and diseases are an integral element of a genetic improvement program. For this purpose, an evaluation of chickpea cultivars (24 advanced lines and 6 commercial varieties) was undertaken under field conditions. Three types of disease responses based on a disease rating scale of 1-9 were observed i.e. resistant, moderately resistant, and susceptible. It was noticed that among 30 cultivars, none was highly resistant and asymptomatic or highly susceptible to both diseases. It was remarkably noticed that in the case of Fusarium wilt, all of the chickpea genotypes except one which performed better was categorized as resistant. Contrarily, L124 was scored as moderately susceptible. All the commercial varieties NUT (2018-19), DG-92, Rabat, Black gram, Benezir, and Synyasi were susceptible to Fusarium wilt. In the case of Ascochyta blight, all the germplasm exhibited resistant reactions except one (L124). Out of the six commercial varieties, Black gram and Benezir exhibited resistant reactions. Fusarium wilt and Ascochyta blight gradually increased with time after each observation. Fusarium wilt disease index in the month of March, was significantly higher on commercial varieties, including NUT (2018-19), DG-92, Rabat, Benezir, and Synyasi, ranging between 57.4-61.7% followed by cv. Black gram with a disease index of 53.7%. All the advanced lines had a low disease index as compared to commercial varieties. Similarly, in the month of March, the disease index of Ascochyta blight was lowest on L102 (38.9%) and the highest on Nut-2018-19 (59.3%) followed by Rabat and Synyasi. Significantly maximum 1000 grain weight was recorded in DG-92, L10, and L119, ranging from 304.3-305.3 g. In terms of grain yield/hectare, L117, L124, NUT (2018-19) and Black gram produced a significantly maximum yield (2916.7-2868.1 kg/ha) followed by Rabat (2638.9 kg/ha) and Synyasi (2520.8 kg/ha) whereas, the lowest yield was recorded in L121. The disease severity of both diseases was positively correlated with 100-grain weight as well as with grain yield. The study revealed the availability of resistant germplasm against two important diseases (Fusarium wilt and Ascochyta blight) which may be exploited in the breeding program for the development of disease-resistant cultivars and may be incorporated with high-yielding cultivars which are clearly evident in the present study.

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Ge, Xueliang, Chandra Sekhar Mandava, Christoffer Lind, Johan Åqvist, and Suparna Sanyal. "Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association." Proceedings of the National Academy of Sciences 115, no. 18 (April 23, 2018): 4649–54. http://dx.doi.org/10.1073/pnas.1802001115.

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The interaction between the ribosomal-stalk protein L7/12 (L12) and initiation factor 2 (IF2) is essential for rapid subunit association, but the underlying mechanism is unknown. Here, we have characterized the L12–IF2 interaction on Escherichia coli ribosomes using site-directed mutagenesis, fast kinetics, and molecular dynamics (MD) simulations. Fifteen individual point mutations were introduced into the C-terminal domain of L12 (L12-CTD) at helices 4 and 5, which constitute the common interaction site for translational GTPases. In parallel, 15 point mutations were also introduced into IF2 between the G4 and G5 motifs, which we hypothesized as the potential L12 interaction sites. The L12 and IF2 mutants were tested in ribosomal subunit association assay in a stopped-flow instrument. Those amino acids that caused defective subunit association upon substitution were identified as the molecular determinants of L12–IF2 interaction. Further, MD simulations of IF2 docked onto the L12-CTD pinpointed the exact interacting partners—all of which were positively charged on L12 and negatively charged on IF2, connected by salt bridges. Lastly, we tested two pairs of charge-reversed mutants of L12 and IF2, which significantly restored the yield and the rate of formation of the 70S initiation complex. We conclude that complementary charge-based interaction between L12-CTD and IF2 is the key for fast subunit association. Considering the homology of the G domain, similar mechanisms may apply for L12 interactions with other translational GTPases.

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Lin, Tz-Feng, Wei-Chieh Wang, Xin-Yu Zeng, Yi-Xian Lu, and Pei-Jung Shih. "Preparation, Structural Characterization of Anti-Cancer Drugs-Mediated Self-Assembly from the Pluronic Copolymers through Synchrotron SAXS Investigation." Materials 15, no. 15 (August 5, 2022): 5387. http://dx.doi.org/10.3390/ma15155387.

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Chemotherapy drugs are mainly administered via intravenous injection or oral administration in a very a high dosage. If there is a targeted drug vehicle which can be deployed on the tumor, the medical treatment is specific and precise. Binary mixing of biocompatible Pluronic® F127 and Pluronic® L121 was used in this study for a drug carrier of pluronic biomedical hydrogels (PBHs). Based on the same PBH ingredients, the addition of fluorouracil (5-FU) was separated in three ways when it was incorporated with pluronics: F127-L121-(5-FU), F127-(5-FU), and L121-(5-FU). Small angle X-ray scattering experiments were performed to uncover the self-assembled structures of the PBHs. Meanwhile, the expected micelle and lamellar structural changes affected by the distribution of 5-FU were discussed with respect to the corresponding drug release monitoring. PBH-all with the mixing method of F127-L121-(5-FU) has the fastest drug release rate owing to the undulated amphiphilic boundary. In contrast, PBH-2 with the mixing method of L121-(5-FU) has a prolonged drug release rate at 67% for one month of the continuous drug release experiment because the flat lamellar amphiphilic boundary of PBH-2 drags the migration of 5-FU from the hydrophobic core. Therefore, the PBHs developed in the study possess great potential for targeted delivery and successfully served as a microenvironment model to elucidate the diffusion pathway of 5-FU.

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Han, Chang-Suk, Kyung-Wan Koo, and Dong-Cheol Oh. "A Study on the Precipitation Behavior of Carbide Particle in L12-type Intermetallic Compound Ni3Al." Korean Journal of Materials Research 16, no. 4 (April 27, 2006): 241–47. http://dx.doi.org/10.3740/mrsk.2006.16.4.241.

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Дисертації з теми "L12D"

Mandava, Chandra Sekhar. "Ribosomal Stalk Protein L12 : Structure, Function and Application." Doctoral thesis, Uppsala universitet, Struktur- och molekylärbiologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-157198.

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Ribosomal stalk proteins are known to play important role in protein synthesis. The ‘stalk’, an extended structure on the large subunit of the ribosome is composed mainly of two to three dimers of L12 and one L10 protein, which forms the base of the stalk. In E. coli, four copies of L12 molecules exist as dimer of dimers forming the pentameric L8 complex together with L10. This thesis is a collection of four interlinked studies on the structure, function and application of the ribosomal stalk protein L12. In the first study, we have mapped the interaction sites of the four major translation GTPase factors (IF2, EF-Tu, EF-G & RF3) on L12 molecule using heteronuclear NMR spectroscopy. Surprisingly, all these factors produced an overlapping interaction map spanning two α-helices on the C terminal domain of L12, thereby suggesting a general nature of the interaction between L12 and the GTPase factors. L12 is known to stimulate GTPase activity of the elongation factors EF-Tu and EF-G. Here, we have clarified the role of L12 in IF2 mediated initiation of protein synthesis. Our data suggest that rapid subunit association requires a specific interaction between the L12 protein on the 50S and IF2·GTP on the 30S preinitiation complex. We have also shown that L12 is not a GAP for IF2 and GTP hydrolysis triggers IF2 release from the 70S initiation complex. The next question we have addressed is why multiple copies of L12 dimer are needed on the ribosome. For this purpose, we created a pure E. coli strain JE105, where the terminal part of rplJ gene coding for the binding site of one L12 dimer on protein L10 was deleted in the chromosomal locus. Using ribosomes with single L12 dimer we have observed that the rate of the initiation and elongation involving IF2 and EF-G gets most compromised, which in turn decreases the growth rate of the bacteria. This study also indicates that L12 can interact with different GTPase factors in a specialized manner. Lastly, we have developed an application making advantage of the multiple L12 dimers on the ribosome. By inserting a (His)6-tag at the C-terminus of the L12 protein we have created a novel E. coli strain (JE28), where all ribosomes are tetra-(His)6-tagged. Further, we have developed a single step method for purification of the active (His)6-tagged ribosomes from JE28.

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Lacasse, Marie-Lou. "L'enracinement des rosiers 'Champlain' et 'Royal Edward' fleuris in vitro." Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25801/25801.pdf.

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del, Mar Diaz del Pino maría, and Jakub sznurowski. "Design of a fuel tank in Volvo frontloader L120 : Effects of the baffles on reducing liquid sloshing." Thesis, Linnéuniversitetet, Institutionen för maskinteknik (MT), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-36000.

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Sloshing phenomena could seriously damage tank structures and reduce its lifetime. On the one hand, studies directly recommend the use of baffles to solve these problems, nevertheless on the other hand the existence of small tanks or plastic tanks without baffles confuse and complicate the case. The first aim in this thesis is to clarify the necessity of baffles for a particular diesel tank L120 H-Generation in Volvo front loaders. Then, the second aim is to improve the existing design. Four configurations are proposed and checked independently. Experiments in the lab, FEM static stresses analyses and vibrational simulations are done in order to fulfill the requirements. The conclusion of this thesis is that the dissipation of energy is highly recommended, so having an oblique baffle with holes could be a good way to reduce the sloshing and extend the lifetime of the tank.

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Tsunashima, Shigeru, Satoshi Iwata, Yukihiro Yamauchi, Daiki Oshima, and Takeshi Kato. "Fabrication of L12-CrPt3 Alloy Films Using Rapid Thermal Annealing for Planar Bit Patterned Media." IEEE, 2010. http://hdl.handle.net/2237/14454.

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Burnett, Tracey A. "Analysis of the novel surface protein P159 and the ribosomal protein L7/L12 of mycoplasma hyopneumoniae." Access electronically, 2005. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20051104.145934/index.html.

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Garimella, Narayana. "Multicomponent Interdiffusion in Austenitic NI-, FE-NI-Base Alloys and L12-NI3AL Intermetallic for High-Temperature Applications." Doctoral diss., University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3894.

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Interdiffusion in multicomponent-multiphase alloys is commonly encountered in many materials systems. The developments of multicomponent-multiphase alloys require control of microstructure through appropriate heat treatment, involving solid-state transformations, precipitation processes, and surface modification, where the interdiffusion processes play a major role. In addition, interdiffusion processes often control degradation and failure of these materials systems. Enhanced performance and reliable durability always requires a detailed understanding of interdiffusion. In this study, ternary and quaternary interdiffusion in Ni-Cr-X (X = Al, Si, Ge, Pd) at 900[degrees]C and 700[degrees]C, Fe-Ni-Cr-X (X = Si, Ge) at 900[degrees]C, and Ni3Al alloyed with Ir, Ta and Re at 1200[degrees]C were examined using solid-to-solid diffusion couples. Interdiffusion fluxes of individual components were calculated directly from experimental concentration profiles determined by electron probe microanalysis. Moments of interdiffusion fluxes were examined to calculate main and cross interdiffusion coefficients averaged over selected composition ranges from single diffusion couple experiments. Consistency in the magnitude and sign of ternary and quaternary interdiffusion coefficient were verified with interdiffusion coefficients determined by Boltzmann-Matano analysis that requires multiple diffusion couples with intersecting compositions. Effects of alloying additions, Al, Si, Ge and Pd, on the interdiffusion in Ni-Cr-X and Fe-Ni-Cr-X alloys were examined with respect to Cr2O3-forming ability at high temperature. Effects of Ir, Ta and Re additions on interdiffusion in Ni3Al were examined with respect to phase stability and site-preference. In addition, a numerically refined approach to determine average ternary interdiffusion coefficients were developed. Concentrations and moments of interdiffusion fluxes are employed to generate multiple combinations of multicomponent interdiffusion coefficient as a function of moments. The matrix of multicomponent interdiffusion coefficients corresponds to the lowest order of the moment. It yields real and positive eigen values which provides reliable average interdiffusion coefficients for the selected composition range.
Ph.D.
Department of Mechanical, Materials and Aerospace Engineering;
Engineering and Computer Science
Materials Science & Engr PhD

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Labonté, Gilles. "Les bibliothèques privées à Québec (1820-1829)." Master's thesis, Université Laval, 1986. http://hdl.handle.net/20.500.11794/29136.

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Labonté, Marie-Hélène. "La protection de la jeunesse vue par des parents réfugiés : la famille au cœur de la protection de la jeunesse." Master's thesis, Université Laval, 2010. http://hdl.handle.net/20.500.11794/22222.

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Afin de protéger leur vie et celle de leur famille, les réfugiés choisissent de quitter leur pays pour obtenir une protection internationale. Arrivés au pays d'accueil, de nouvelles réalités sociales s'imposent à eux. La Direction de la protection de la jeunesse (DPJ), institution de la protection de la jeunesse, en est une importante. Au nom de la protection des enfants, elle peut intervenir en autorité dans la famille alors même que celle-ci vit une période d'adaptation due à la migration. Comment des parents réfugiés récemment arrivés se représentent-ils cette institution? Telle est la question à laquelle le mémoire répondra. La présente étude aborde cette question à partir du cadre théorique des représentations sociales et en réalisant des entrevues semi-dirigées auprès de parents réfugiés afin d'obtenir leurs représentations de la DPJ et ce qui influence leur élaboration. Les résultats de l'étude suggèrent l'élaboration de deux représentations soit ± aide aux enfants et à la famille ¿ et ± contrôle des parents et des familles ¿. De même, les expériences avec la DPJ et les observations dans la communauté, les connaissances préalables à la migration concernant la protection des enfants, la vision de la famille et de l'éducation ainsi que le vécu de réfugiés sont tous des éléments influençant l'élaboration de leur représentation. Le mémoire examine dans un dernier temps, les limites de l'étude et les résultats à la lumière de la littérature contemporaine. L'étude conclut en rappelant l'importance de tenir compte dans l'intervention de la signification de la famille pour les parents réfugiés. Elle dégage des pistes d'intervention pouvant prévenir des signalements à la DPJ et pouvant favoriser une adéquation des services de DPJ avec les besoins des réfugiés. Des pistes de recherche sont également proposées.

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Elhag, Gasmalla Abdelwahab. "Molecular characterization of full-length cDNAs for nuclear-encoded chloroplast ribosomal proteins L12, L24 and L27 of Nicotiana tabacum." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185581.

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Poly(A)⁺ mRNA isolated from Nicotiana tabacllm (cv. Petite havana) leaves was used to prepare a cDNA library in the expression vector Agtll. The library was screened with antibodies raised against proteins of chloroplast 50S ribosomal subunits. Full length cDNAs for three nuclear-encoded tobacco chloroplast large ribosomal subunit proteins were identified and sequenced. The deduced protein sequences are homologous to E. coli ribosomal proteins L12 (involved in GTP hydrolysis), L24 (a ribosomal RNA binding protein) and L27 (a constituent of peptidyltransferase ). The full-length cDNA encoding tobacco chloroplast ribosomal protein L12 is 773 nucleotides long, and encodes a mature protein of 133 amino acids and a transit peptide of 53 amino acids. The amino terminus of the mature protein was confirmed by protein sequencing of the first 12 amino acids. The deduced amino acid sequence of tobacco L12 protein has a high degree of identity with chloroplast ribosomal protein L12 of spinach (70%) and E. coli (51 % ). A full-length cDNA encoding tobacco chloroplast ribosomal protein L24 is 862 nucleotides long and encodes a mature protein of 157 amino acids and a putative transit peptide of 30 amino acids. The deduced amino acid sequence of tobacco L24 protein has a high degree of identity with chloroplast ribosomal protein L24 of pea (73%) and E. coli (35%). The fusion protein from the clone coding the tobacco L24 ribosomal protein was bound to nitrocellulose filters and used as affinity matrix to purify the antibody to the L24 protein. Monospecific antibody to L24 was used to identify, by Western blotting, the L24 ribosomal protein among purified proteins of the large subunit of the chloroplast ribosome. A full-length eDNA encoding tobacco ribosomal protein L27 is 882 nucleotides long and encodes a mature protein of 128 amino acids and a putative transit peptide of 51 amino acids. The deduced amino acid sequence of tobacco L27 protein has a high degree of identity with E. coli ribosomal protein L27 (64%) in the overlapping region between the two proteins. Besides the transit peptide, both ribosomal proteins L24 and L27 sequences have a carboxyl-terminal extension. Using Northern blot analysis, unique full size cytoplasmic mRNAs were observed for the three different proteins. For each of the three proteins (L12, L24, L27), at least two cDNAs with identical coding sequence and different 3'-non-coding sequences were identified. Southern blot analysis of genomic DNA indicated the presence of more than one gene for each of the three proteins. Furthermore, genomic clones likely to represent two different genes were isolated for tobacco ribosomal protein L27.

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Labrecque, Martine. "JONATHAN LE GOÉLAND: Conte universel ou récit délibérément ésotérique?" Thesis, Université Laval, 2011. http://www.theses.ulaval.ca/2011/28411/28411.pdf.

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Книги з теми "L12D"

Pelleg, Joshua. Diffusion in the Iron Group L12 and B2 Intermetallic Compounds. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7.

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Sauget, Joseph-Marie. Le Paterikon arabe de la Bibliothèque Ambrosienne de Milan l120 sup.(SP 11.161). Roma: Accademia Nazionale di Lincei, 1989.

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Commission of the European Communities. DIR 89/336/EEC: Council directive of 3 May 1989 on the harmonisation of the laws of member states relating to electromagnetic compatability : amended by Dir 92/31/EEC in "Official Journal" L126/92 of 28 April 1992. Luxembourg: Office for Official Publications of the European Communities, 1992.

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L12 Ordered Alloys. Elsevier, 1996. http://dx.doi.org/10.1016/s1572-4859(96)x8001-x.

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Duesbery, M. S., and Frank Nabarro. L12 Ordered Alloys. Elsevier Science & Technology Books, 1996.

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Ochi, Kaz. Acctg W L123 Text & Temp Disk. South-Western Educational Publishing, 1997.

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Hutchinson. CE/Wp51/L123 R24/Qbasic Pkg. Irwin, 1994.

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Williams. Uit/CDROM/Db3+/L123 R31 Pkg. Irwin, 1995.

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Hudson. Cost Acctg Prob Usg L123 Manual. Not Avail, 1997.

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Hutchinson. Comp Essent/Dos50/Dbasiv/Wp51/L123. Irwin, 1994.

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Частини книг з теми "L12D"

Schneibel, J. H., and P. M. Hazzledine. "Creep in L12-Intermetallics." In Ordered Intermetallics — Physical Metallurgy and Mechanical Behaviour, 565–81. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2534-5_35.

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Pelleg, Joshua. "Diffusion Mechanisms in L12 Structures." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 23–28. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_2.

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Yavari, A. R., P. Crespo, E. Pulido, A. Hernando, G. Fillion, P. Lethuillier, M. D. Baro, and S. Surinach. "Magnetic Properties of Disordered L12-Ni3Al + Fe." In Ordering and Disordering in Alloys, 12–22. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2886-5_2.

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Schweiger, H., R. Podloucky, W. Püschl, M. Spanl, and W. Pfeiler. "Point Defect Energies in L12-Ordered Ni3Al." In Properties of Complex Inorganic Solids 2, 187–97. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-1205-9_15.

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Ricolleau, Ch, A. Loiseau, and F. Ducastelle. "Electron Microscopy Investigation of Wetting Phenomena in L12 Alloys." In Ordering and Disordering in Alloys, 114–21. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2886-5_11.

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Pelleg, Joshua. "Diffusion Equations and Mechanisms." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 3–20. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_1.

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Pelleg, Joshua. "Diffusion in CoAl." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 295–307. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_10.

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Pelleg, Joshua. "Diffusion in CoGa." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 309–19. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_11.

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Pelleg, Joshua. "Diffusion in FeAl." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 323–55. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_12.

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Pelleg, Joshua. "Diffusion in Ni3Al." In Diffusion in the Iron Group L12 and B2 Intermetallic Compounds, 31–147. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39522-7_3.

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Тези доповідей конференцій з теми "L12D"

Yang, Weiguang, Yuxin Wang, Yulong Yu, Guangyuan Kan, and He Guo. "DD-L1D: Improving the Decoupled L1D Efficiency for GPU Architecture." In 2017 International Conference on Networking, Architecture, and Storage (NAS). IEEE, 2017. http://dx.doi.org/10.1109/nas.2017.8026851.

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Zhao, Bingbing, Xianping Dong, Feng Sun, and Lanting Zhang. "Introduction of L12-Ordered Precipitation to Alumina-Forming Austenitic Heat-Resistant Steels With Low Ni Content." In ASME Turbo Expo 2017: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/gt2017-63621.

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Alumina-forming austenitic (AFA) heat-resistant steels have been reported as a promising new class of steels in recent years with potential applications in advanced ultra-supercritical power plants. It is well known that L12-ordered γ’ phase is the most important precipitate for high-temperature strengthening in Ni-based superalloys and it can be stabilized by increasing the Ni content in heat-resistant steels. In the current work, the evolution of L12-ordered precipitates were compared in the Cu-bearing AFA alloys with 20, 27 and 35 wt.% Ni. After slow tensile tests at 700°C (∼2 × 10−5 s−1), L12-ordered precipitates occurred in all the alloys. Alloy AFA27 displayed the most densely distributed L12-particles in the matrix, whose ultimate tensile strength was also the highest. However, the L12-ordered precipitates were only observed in alloy AFA27 after the slow tensile test at 750°C due to the thermodynamic and kinetic reasons. Flow curves of slow tensile tests indicated different precipitation behaviors at 700°C and 750°C. Chemical composition analysis and thermodynamic calculation revealed that the occurrence of L12-ordered Ni-Cu-Al phase depends on temperature, Ni content and the atomic ratio of Ni/Al. This opens up new opportunities to promote the formation of L12-ordered phase in Fe-based austenitic heat-resistant steels with low Ni content and benefits high-temperature strengthening.

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Ming, Di, and Chris Ding. "Robust Flexible Feature Selection via Exclusive L21 Regularization." In Twenty-Eighth International Joint Conference on Artificial Intelligence {IJCAI-19}. California: International Joint Conferences on Artificial Intelligence Organization, 2019. http://dx.doi.org/10.24963/ijcai.2019/438.

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Recently, exclusive lasso has demonstrated its promising results in selecting discriminative features for each class. The sparsity is enforced on each feature across all the classes via L12-norm. However, the exclusive sparsity of L12-norm could not screen out a large amount of irrelevant and redundant noise features in high-dimensional data space, since each feature belongs to at least one class. Thus, in this paper, we introduce a novel regularization called "exclusive L21", which is short for "L21 with exclusive lasso", towards robust flexible feature selection. The exclusive L21 regularization is the mix of L21-norm and L12-norm, which brings out joint sparsity at inter-group level and exclusive sparsity at intra-group level simultaneously. An efficient augmented Lagrange multipliers based optimization algorithm is proposed to iteratively solve the exclusive L21 regularization in a row-wise fashion. Extensive experiments on twelve benchmark datasets demonstrate the effectiveness of the proposed regularization and the optimization algorithm as compared to state-of-the-arts.

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"Lokalizatsiya plasticheskoy deformatsii monokristallov splavov so sverkhstrukturoy L12." In Perspektivnye materialy s ierarkhicheskoy strukturoy dlya novykh tekhnologiy i nadezhnykh konstruktsiy, Khimiya nefti i gaza. Tomsk State University, 2018. http://dx.doi.org/10.17223/9785946217408/59.

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Oguma, R. "Formation of Off-Phase Domains in L12 Type Ordering." In FLOW DYNAMICS: The Second International Conference on Flow Dynamics. AIP, 2006. http://dx.doi.org/10.1063/1.2204552.

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Titus, M., A. Suzuki, and T. Pollock. "High Temperature Creep of New L12 Containing Cobalt-base Superalloys." In Superalloys. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.7449/2012/superalloys_2012_823_832.

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Arikan, Nihat, and Mustafa Özduran. "The structural, electronic and dynamic properties of the L12- type Co3Ti alloy." In INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2014 (ICCMSE 2014). AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4897709.

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Tsunoda, M., M. Naka, K. Imakita, and M. Takahashi. "Exchange anisotropy of ferromagnetic/antiferromagnetic bilayers with L12-Mn3(IR, Ru, Rh)." In INTERMAG 2006 - IEEE International Magnetics Conference. IEEE, 2006. http://dx.doi.org/10.1109/intmag.2006.376299.

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JEZIERSKA, ELŻBIETA. "APPLICATION OF LACBED IN STRUCTURAL CHARACTERISATION OF ORDERED INTERMETALLICS WITH L12 SUPERSTRUCTURE." In Proceedings of the XVIII Conference. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812811325_0067.

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Arikan, Nihat. "The structural, electronic, elastic and dynamic properties of Co3W in the L12 phase." In TURKISH PHYSICAL SOCIETY 32ND INTERNATIONAL PHYSICS CONGRESS (TPS32). Author(s), 2017. http://dx.doi.org/10.1063/1.4976379.

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Звіти організацій з теми "L12D"

Bercovier, Herve, Raul Barletta, and Shlomo Sela. Characterization and Immunogenicity of Mycobacterium paratuberculosis Secreted and Cellular Proteins. United States Department of Agriculture, January 1996. http://dx.doi.org/10.32747/1996.7573078.bard.

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Our long-term goal is to develop an efficient acellular vaccine against paratuberculosis based on protein antigen(s). A prerequisite to achieve this goal is to analyze and characterize Mycobacterium paratuberculosis (Mpt) secreted and cellular proteins eliciting a protective immune response. In the context of this general objective, we proposed to identify, clone, produce, and characterize: the Mpt 85B antigen and other Mpt immunoreactive secreted proteins, the Mpt L7/L12 ribosomal protein and other immunoreactive cellular proteins, Mpt protein determinants involved in invasion of epithelial cells, and Mpt protein antigens specifically expressed in macrophages. Paratuberculosis is still a very serious problem in Israel and in the USA. In the USA, a recent survey evaluated that 21.6% of the dairy herd were infected with Mpt resulting in 200-250 million dollars in annual losses. Very little is known on the virulence factors and on protective antigens of Mpt. At present, the only means of controlling this disease are culling or vaccination. The current vaccines do not allow a clear differentiation between infected and vaccinated animals. Our long-term goal is to develop an efficient acellular paratuberculosis vaccine based on Mpt protein antigen(s) compatible with diagnostic tests. To achieve this goal it is necessary to analyze and characterize secreted and cellular proteins candidate for such a vaccine. Representative Mpt libraries (shuttle plasmid and phage) were constructed and used to study Mpt genes and gene products described below and will be made available to other research groups. In addition, two approaches were performed which did not yield the expected results. Mav or Mpt DNA genes that confer upon Msg or E. coli the ability to invade and/or survive within HEp-2 cells were not identified. Likewise, we were unable to characterize the 34-39 kDa induced secreted proteins induced by stress factors due to technical difficulties inherent to the complexity of the media needed to support substantial M. pt growth. We identified, isolated, sequenced five Mpt proteins and expressed four of them as recombinant proteins that allowed the study of their immunological properties in sensitized mice. The AphC protein, found to be up regulated by low iron environment, and the SOD protein are both involved in protecting mycobacteria against damage and killing by reactive oxygen (Sod) and nitrogen (AhpC) intermediates, the main bactericidal mechanisms of phagocytic cells. SOD and L7/L12 ribosomal proteins are structural proteins constitutively expressed. 85B and CFP20 are both secreted proteins. SOD, L7/L12, 85B and CFP20 were shown to induce a Th1 response in immunized mice whereas AphC was shown by others to have a similar activity. These proteins did not interfere with the DTH reaction of naturally infected cows. Cellular immunity provides protection in mycobacterial infections, therefore molecules inducing cellular immunity and preferentially a Th1 pathway will be the best candidate for the development of an acellular vaccine. The proteins characterized in this grant that induce a cell-mediated immunity and seem compatible with diagnostic tests, are good candidates for the construction of a future acellular vaccine.

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Banai, Menachem, and Gary Splitter. Molecular Characterization and Function of Brucella Immunodominant Proteins. United States Department of Agriculture, July 1993. http://dx.doi.org/10.32747/1993.7568100.bard.

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The BARD project was a continuation of a previous BARD funded research project. It was aimed at characterization of the 12kDa immunodominant protein and subsequently the cloning and expression of the gene in E. coli. Additional immunodominant proteins were sought among genomic B. abortus expression library clones using T-lymphocyte proliferation assay as a screening method. The 12kDa protein was identified as the L7/L12 ribosomal protein demonstrating in the first time the role a structural protein may play in the development of the host's immunity against the organism. The gene was cloned from B. abortus (USA) and B. melitensis (Israel) showing identity of the oligonucleotide sequence between the two species. Further subcloning allowed expression of the protein in E. coli. While the native protein was shown to have DTH antigenicity its recombinant analog lacked this activity. In contrast the two proteins elicited lymphocyte proliferation in experimental murine brucellosis. CD4+ cells of the Th1 subset predominantly responded to this protein demonstrating the development of protective immunity (g-IFN, and IL-2) in the host. Similar results were obtained with bovine Brucella primed lymphocytes. UvrA, GroE1 and GroEs were additional Brucella immunodominant proteins that demonstrated MHC class II antigenicity. The role cytotoxic cells are playing in the clearance of brucella cells was shown using knock out mice defective either in their CD4+ or CD8+ cells. CD4+ defective mice were able to clear brucella as fast as did normal mice. In contrast mice which were defective in their CD8+ cells could not clear the organisms effectively proving the importance of this subtype cell line in development of protective immunity. The understanding of the host's immune response and the expansion of the panel of Brucella immunodominant proteins opened new avenues in vaccine design. It is now feasible to selectively use immunodominant proteins either as subunit vaccine to fortify immunity of older animals or as diagnostic reagents for the serological survaillance.

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