Готові списки джерел за темами / IspG

Добірка наукової літератури з теми "IspG"

Автор: Grafiati
Опубліковано: 7 липня 2024

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Зміст

  1. Статті в журналах
  2. Дисертації
  3. Книги
  4. Частини книг
  5. Тези доповідей конференцій
  6. Звіти організацій

Статті в журналах з теми "IspG":

1

Guerra, Francisco, Ke Wang, Jikun Li, Weixue Wang, Yi-Liang Liu, Shivani Amin, and Eric Oldfield. "Inhibition of the 4Fe–4S proteins IspG and IspH: an EPR, ENDOR and HYSCORE investigation." Chem. Sci. 5, no. 4 (2014): 1642–49. http://dx.doi.org/10.1039/c3sc53301h.

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2

Zhou, Jia, Liyang Yang, Chonglong Wang, Eui-Sung Choi, and Seon-Won Kim. "Enhanced performance of the methylerythritol phosphate pathway by manipulation of redox reactions relevant to IspC, IspG, and IspH." Journal of Biotechnology 248 (April 2017): 1–8. http://dx.doi.org/10.1016/j.jbiotec.2017.03.005.

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3

Liu, Chunyu, Sian Hemmings, and Thomas G. Schulze. "ISPG GLOBAL DIVERSITY PROPOSAL." European Neuropsychopharmacology 29 (2019): S1039. http://dx.doi.org/10.1016/j.euroneuro.2018.07.039.

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4

Lu, Zhifang, Biying Wang, Zhiyu Qiu, Ruiling Zhang, Jimin Zheng, and Zongchao Jia. "YdfD, a Lysis Protein of the Qin Prophage, Is a Specific Inhibitor of the IspG-Catalyzed Step in the MEP Pathway of Escherichia coli." International Journal of Molecular Sciences 23, no. 3 (January 29, 2022): 1560. http://dx.doi.org/10.3390/ijms23031560.

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Bacterial cryptic prophage (defective prophage) genes are known to drastically influence host physiology, such as causing cell growth arrest or lysis, upon expression. Many phages encode lytic proteins to destroy the cell envelope. As natural antibiotics, only a few lysis target proteins were identified. ydfD is a lytic gene from the Qin cryptic prophage that encodes a 63-amino-acid protein, the ectopic expression of which in Escherichia coli can cause nearly complete cell lysis rapidly. The bacterial 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway is responsible for synthesizing the isoprenoids uniquely required for sustaining bacterial growth. In this study, we provide evidence that YdfD can interact with IspG, a key enzyme involved in the MEP pathway, both in vivo and in vitro. We show that intact YdfD is required for the interaction with IspG to perform its lysis function and that the mRNA levels of ydfD increase significantly under certain stress conditions. Crucially, the cell lysis induced by YdfD can be abolished by the overexpression of ispG or the complementation of the IspG enzyme catalysis product methylerythritol 2,4-cyclodiphosphate. We propose that YdfD from the Qin cryptic prophage inhibits IspG to block the MEP pathway, leading to a compromised cell membrane and cell wall biosynthesis and eventual cell lysis.
5

Trofimov, Leonid N., Ivan L. Trofimov, and Sergei V. Podkovalnikov. "North-east Asia interstate power grid expansion in the conditions of possible economic recession in China." E3S Web of Conferences 216 (2020): 01007. http://dx.doi.org/10.1051/e3sconf/202021601007.

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The article considers scenarios of the prospective interstate power grid (ISPG) expansion in Northeast Asia with possible economic recession in China because of COVID-19 and other factors. Features of optimization of new capacities addition of renewable energy sources in the ISPG are considered. A series of computational experiments with variations in the profiles of wind and solar power plants were carried out. The assessment of impact the intermittence of renewable energy power output on the structure of ISPG was evaluated, with taking into account of possible economic recession in China. A comparative analysis of solutions to the problem of optimization of intermittent generation capacity inputs for scenarios with the formation of an energy connection in northeast Asia and its absence is carried out.
6

Propping, Peter. "ISPG lifetime achievement award 2004." American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 136B, no. 1 (2005): 1. http://dx.doi.org/10.1002/ajmg.b.30208.

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7

Lee, Mon-Chien, Yi-Ju Hsu, Li-Hsuan Yang, Chi-Chang Huang, and Chun-Sheng Ho. "Ergogenic Effects of Green Tea Combined with Isolated Soy Protein on Increasing Muscle Mass and Exercise Performance in Resistance-Trained Mice." Nutrients 13, no. 12 (December 18, 2021): 4547. http://dx.doi.org/10.3390/nu13124547.

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It is well known that supplementation with high protein after exercise can effectively promote muscle synthesis and repair, while green tea is rich in catechins that have antioxidant effects. We aimed to explore the effects of green tea combined with isolated soy protein on increase muscle mass in resistance-trained mice. A total of 32 male ICR mice (8-weeks old) were divided into four groups (n = 8/group), sedentary control group (SC), isolated soy protein with green tea group (ISPG), resistance training group (RT), isolated soy protein and green tea combine with resistance training group (ISPG + RT). All mice received control or ISPG by oral gavage for four consecutive weeks. Forelimb grip and exhaustive swimming time were used for exercise performance evaluation. In biochemical profile, we analyzed lactate, ammonia, blood urea nitrogen (BUN), and glucose and muscle damage index creatine kinase (CK) after exercise as biochemical parameters of exercise fatigue. The grip strength, muscular endurance, and exhaustive swimming time of the ISPG + RT group were significantly increased than other groups (p < 0.05), and also significantly decreased in serum lactate and ammonia levels (p < 0.05, respectively). The ISP + RT group was not only increased in quadriceps weight, (p < 0.05) but also decreased EFP (p < 0.05). We recommend using a 4-week supplementation with ISPG, combined with RT, to increase muscle mass, exercise performance, glycogen storage, and reduce fatigue biochemical parameters after exercise. The benefits of long-term supplementation or application to human supplementation can be further explored in the future.
8

Meinke-Carstanjen, Annette. "Aus Pflegeleitern werden Manager." kma - Klinik Management aktuell 10, no. 04 (April 2005): 94–95. http://dx.doi.org/10.1055/s-0036-1573264.

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Die Hochschule Bremen stellt den Diplom-Studiengang Internationale Pflegeleitung (ISP) auf Bachelor und Master um. Betriebswirtschaft und Management werden bei dem neuen Internationalen Studiengang Pflege- und Gesundheitsmanagement (ISPG) viel stärker im Visier stehen: Der Anteil erhöht sich um fast ein Drittel.
9

Rohdich, F., Stefan Hecht, Adelbert Bacher, and Wolfgang Eisenreich. "The deoxyxylulose phosphate pathway of isoprenoid biosynthesis. Discovery and function of the ispDEFGH genes and their cognate enzymes." Pure and Applied Chemistry 75, no. 2-3 (January 1, 2003): 393–405. http://dx.doi.org/10.1351/pac200375020393.

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Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) serve as the universal precursors for the biosynthesis of terpenes. Besides the well-known mevalonate pathway, a second biosynthetic pathway conducive to IPP and DMAPP via 1-deoxy-d-xylulose-5-phosphate and 2C-methyl-d-erythritol-4-phosphate has been discovered recently in plants and certain eubacteria. 2C-Methyl-d-erythritol-4-phosphate, the first committed intermediate of the deoxyxylulose phosphate pathway, is converted into 2C-methyl-d-erythritol 2,4-cyclodiphosphate by the catalytic action of three enzymes specified by the ispDEF genes. The cyclic diphosphate is reductively opened by the IspG protein affording 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate. This compound can be converted into IPP as well as DMAPP by the catalytic action of IspH protein. The enzymes of this pathway are potential targets for novel antibacterial, antimalarial, and herbicide agents.
10

Nyland II, Rodney L., Youli Xiao, Pinghua Liu, and Caren L. Freel Meyers. "IspG Converts an Epoxide Substrate Analogue to (E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate: Implications for IspG Catalysis in Isoprenoid Biosynthesis." Journal of the American Chemical Society 131, no. 49 (December 16, 2009): 17734–35. http://dx.doi.org/10.1021/ja907470n.

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Статті в журналах Дисертації Книги

Дисертації з теми "IspG":

1

Lee, Matthias S. "Biochemische und strukturelle Studien an IspG- und IspH-Proteinfamilien /." München : Verl. Dr. Hut, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=017315255&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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2

D'auria, Lucia. "Caractérisation biophysique et structurale de IspG et IspH (en complexe avec des inhibiteurs)." Electronic Thesis or Diss., Université Grenoble Alpes, 2023. http://www.theses.fr/2023GRALV116.

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La résistance aux antibiotiques constitue un défi sanitaire mondial important. L'organisation mondiale de la santé la classant parmi les dix principales menaces pour la santé publique dans le monde ; d’où un besoin urgent de nouveaux anti-infectieux ciblant de nouvelles voies.Dans ce contexte, la voie du méthylerythritol phosphate (MEP) a une importance particulière. La voie MEP est composée de sept enzymes et est responsable de la biosynthèse des précurseurs des isoprénoïdes : le diphosphate d'isopentényle (IPP) et le diphosphate de diméthylallyle (DMAPP). Cette voie est totalement absente chez l'homme mais est essentielle pour des microorganismes tels que Mycobacterium tuberculosis (Mt), Plasmodium falciparum (Pf), Pseudomonas aeruginosa (Pa).Le but de ce projet était d'élucider les structures cristallographiques des deux dernières enzymes de la voie MEP (IspG et IspH) de trois pathogènes (P. aeruginosa, M. tuberculosis et P. falciparum) et ensuite, en combinant le criblage cristallographique aux rayons X de fragments et le criblage virtuel in silico de chimiothèques, d'identifier ou de concevoir de nouveaux inhibiteurs spécifiques de ces enzymes.En raison de la présence d'un cluster 4Fe-4S dans leurs sites actifs, toutes ces enzymes sont sensibles à l'oxygène et doivent être manipulées en boîte à gants dans des conditions anaérobies. La première partie de ce travail a consisté à produire et purifier chacune des six protéines en quantité suffisante aux études de cristallisation. Les trois IspH ainsi que Pa et MtIspG ont pu être purifiés.Les réactions catalysées par IspG et IspH dépendent d'un système donneur d'électrons. Chez Plasmodium, ce système est composé de deux protéines: la ferrédoxine (PfFd) et la ferrédoxine-réductase (PfFNR). L'obtention de ces deux protéines actives et en quantités suffisantes était une condition préalable à l'utilisation du système de réduction naturelle pour mesurer les activités enzymatiques de PfIspG et PfIspH. C'est pourquoi l'optimisation de l'expression et de la purification de PfFd et PfFNR a également été réalisée au cours de la première partie de ce projet. Les tests d'activité ont été réalisés avec succès pour PfIspH par le groupe du Dr. Myriam Seemann, nos collaborateurs à l'Université de Strasbourg. Ils ont également utilisé le système Plasmodium pour cribler différentes séries de composés chimiques in vitro.Le criblage des conditions de cristallisation a été réalisé en boite à gants avec toutes les protéines purifiées. Les cristaux obtenus ont été analysés à l’European Synchrotron Radiation Facility (ESRF). Les données recueillies ont permis d'élucider les premières structures cristallographiques de PaIspH et MtIspH à des résolutions de 1.5 Å et 2.8 Å, respectivement. Ces deux enzymes présentent le repliement typique de la famille IspH en trèfle à trois feuilles.PaIspH contient un cluster 3Fe-4S incomplet et une molécule de bicine provenant du tampon de cristallisation dans son site actif. La bicine interagit avec des résidus clés impliqués dans la liaison du substrat, mais n'a pas d'activité inhibitrice. Cependant, cela nous a permis d'obtenir des informations structurales sur les interactions possibles au sein du site actif, ce qui pourra aider à la conception de nouveaux inhibiteurs.Dans le cas de MtIspH, un déplacement du troisième domaine entraîne une ouverture inédite du site actif. Malgré cette ouverture, MtIspH présente un cluster 4Fe-4S. Cela peut s'expliquer par le fait que le déplacement du troisième domaine a rapproché le cluster de la thréonine 189, qui peut désormais se lier au fer apical et le stabiliser.Grâce à ces nouvelles structures, nous avons réalisé des criblages virtuels in silico de différentes chimiothèques. Certains composés identifiés in silico ainsi que de nouveaux inhibiteurs sélectionnés in vitro par nos collaborateurs de Strasbourg ont été utilisés pour des essais de co-cristallisation
Antimicrobial resistance poses a significant global health challenge, with the World Health Organization ranking it among the top 10 global threats to public health worldwide. Hence, the urgent need for new anti-infectives targeting novel pathways.In this context, the Methylerythritol phosphate (MEP) pathway becomes particularly significant. The MEP pathway is composed of seven enzymes and is responsible for the biosynthesis of the two isoprenoids precursors: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). This pathway is completely absent in humans but is essential to pathogenic microorganisms such as Mycobacterium tuberculosis (Mt), Plasmodium falciparum (Pf), Pseudomonas aeruginosa (Pa).The aims of this project were to elucidate the crystallographic structures of the last two enzymes of the MEP pathway (IspG and IspH) from three different pathogens (P. aeruginosa, M. tuberculosis and P. falciparum) and by combining X-ray fragment screening and in silico virtual screening of chemical libraries, to identify or design new specific inhibitors of these enzymes.Due to the presence of a 4Fe-4S cluster in their active sites, all these targets are oxygen-sensitive enzymes that must be handled under anaerobic conditions using a glove-box. The first part of this work consisted in establishing a protocol for the production and purification of each of the six proteins in quantity suitable for crystallization studies. Pure proteins were obtained for all the IspH orthologues and for Pa and MtIspG.The reactions catalyzed by IspG and IspH are dependent on an electron donating system. For Plasmodium, this system is composed of two proteins: the ferredoxin (a 2Fe-2S cluster, PfFd) and the ferredoxin-reductase (a FAD dependent protein, PfFNR). Obtaining these two active proteins in sufficient quantities was necessary for using the natural reduction system for measuring the enzymatic activities of PfIspG and PfIspH. That’s why the optimization of the expression and purification of PfFd and PfFNR was also achieved during the first part of this project. The activity tests were performed successfully with PfIspH by the group of Dr. Myriam Seemann, our close collaborators at the University of Strasbourg. They also used the Plasmodium system to screen different series of chemical compounds in vitro.Crystallization screening under anaerobic conditions were performed for all the IspG and IspH proteins obtained. Several crystals were obtained and analyzed at the European Synchrotron Radiation Facility (ESRF). The collected data led to the elucidation of the first crystallographic structures of PaIspH and MtIspH at 1.5 Å and 2.8 Å resolution, respectively. Both enzymes show a three-leaf clover folding typical of the IspH family.PaIspH contains an incomplete 3Fe-4S cluster and a molecule of bicine coming from the crystallization buffer in its active site. The bicine is interacting with key residues involved in the substrate binding, but has no inhibitory activity. However, this has provided us structural information on possible interactions within the active site, which may help in the design of new inhibitors.For MtIspH, a shift in the third domain leads to a previously unseen opening of the active site. Surprisingly, despite this opening, MtIspH displays a 4Fe-4S cluster. This can be explained by the fact that the displacement of the third domain has brought the cluster closer to the threonine 189, which can bind and stabilize the apical iron.Some of the compounds identified in silico as well as new inhibitors selected in vitro by our collaborators in Strasbourg have been used for co-crystallization assays. The new structural information combined with the in silico docking analysis and the enzymatic activity assays, opens the door for new biophysical and structural studies of these fascinating enzymes that are targeted for the development of new anti-infectives
3

Zepeck, Ferdinand. "Charakterisierung der 1-Hydroxy-2-methyl-2-(E)-butenyl-4-diphosphat-Synthase (IspG-Protein)." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980363721.

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4

Lauw, Susan. "Characterization and inhibition of the IspC, IspE and IspF proteins involved in the deoxyxylulose phosphate pathway of isoprenoids biosynthesis." kostenfrei, 2008. http://mediatum2.ub.tum.de/doc/669162/669162.pdf.

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5

Santos, Juliete Vitorino dos. "Expressão e purificação da forma recombinante dos Inibidores de Serino Peptidase ISP1 e ISP2 de Leishmania infantum chagasi." reponame:Repositório Institucional da UFABC, 2017.

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Анотація:
Orientadora: Profª Drª Márcia Aparecida Sperança
Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Biossistemas, 2017.
A leishmaniose visceral, causada pelos parasitas das espécies Leishmania infantum e Leishmania donovani, do Velho Mundo, e pela Leishmania infantum chagasi, do Novo Mundo, é uma doença infecciosa e letal se não for tratada. O número de casos desta doença está aumentando no Estado de São Paulo. Uma vez diagnosticada, o tratamento para a leishmaniose visceral tem efeitos colaterais importantes, além da ocorrência de parasitas resistentes aos medicamentos disponíveis. Sabe-se que algumas peptidases desempenham um papel importante na fisiologia e doença causada por parasitas do género Leishmania. A inibição específica destas enzimas pode constituir uma importante estratégia para a produção de potentes agentes antiparasitários. Em bactérias E. coli, inibidores de serino peptidases (ISPs) denominados ecotinas, têm sido descritos, sendo também identificados em espécies de Leishmania. A caracterização funcional da ISP1 e ISP2 de L. major mostrou o seu papel na formação de flagelo de promastigotas e na inibição da elastase de neutrófilos de hospedeiro vertebrado, respectivamente. Portanto, os objetivos deste projeto são a expressão e a purificação das proteínas ISP1 e ISP2 de L. i. chagasi (LcISP1 e LcISP2) recombinantes. A amplificação das sequências que codificam as LcISP1 e LcISP2 foi realizada por PCR a partir do DNA genômico, de L. i. chagasi extraído de uma estirpe de referência cedida pelo Laboratório Nacional de Referência de Espécies de Leishmania da Fiocruz, Rio de Janeiro. Os fragmentos de PCR foram clonados no vetor de expressão bacteriano pET28a e as proteínas recombinantes LcISP2 e LcISP1 foram obtidas na fração solúvel do extrato proteico bacteriano. Após expressão das proteínas recombinantes, elas foram purificadas por cromatografia de afinidade em níquel.
Visceral leishmaniasis, caused by the Old World parasites species Leishmania infantum and Leishmania donovani, and by the New World Leishmania infantum chagasi, is an infectious and lethal disease, if untreated. The number of cases of this disease is increasing in the State of São Paulo. Once diagnosed, treatment for visceral leishmaniasis has important side effects, besides occurrence of parasites resistant to the available drugs. It is known that some peptidases play an important role in physiology and disease caused by parasites of the genus Leishmania. The specific inhibition of these enzymes may constitute an important strategy for producing potent antiparasitic agents. In bacteria E. coli, inhibitors of serine peptidases (ISPs) called ecotins, have been described, being also identified in Leishmania species. Characterization of genes encoding ISP1 and ISP2 of L. major, showed its role in the promastigote flagellum formation and in the inhibition of vertebrate host neutrophil elastase, respectively. Therefore, the aims of this project are to produce L. i. chagasi ISP1 (LcISP1) and ISP2 (LcISP2) recombinant forms and to evaluate the its biochemical activity. Amplification of the LcISP1 and LcISP2 encoding sequences were performed by PCR from L. i. chagasi DNA extracted from a reference strain obtained from the Leishmania collection of the Leishmania National Reference Laboratory of the Instituto Oswaldo Cruz. PCR fragments were cloned into the pET28a bacterial expression vector and the recombinant LcISP1 and LcISP2 proteins were present in soluble bacterial extract fraction. After purification by niquel affinity chromatography, recombinant LcISP1 and LcISP2 proteins e were tested for biochemical activity.
6

Nie, Weiwei. "Plano de marketing – ISEG." Master's thesis, Instituto Superior de Economia e Gestão, 2018. http://hdl.handle.net/10400.5/16570.

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Mestrado em Marketing
O ISEG é relativamente pouco conhecido, no geral, devido às seguintes principais vertentes: a comunicação no mercado chinês e os programas de cooperação com as IES na China. Na fase inicial de exploração do mercado chinês, é fundamental compreendê-lo, assim como conhecer o perfil dos alunos chineses, o que inclui a sua família. O presente projeto tem como principal objetivo explorar o perfil dos alunos chineses e a perceção dos mesmos do contexto português, através de dados secundários e do questionário destinado a alunos que já frequentam cursos de licenciatura, mestrado e doutoramento em Portugal. De modo a perceber os principais pontos fortes e fracos, realiza-se uma análise de concorrência externa e interna. A partir desta análise, identificam-se as partes que se devem melhorar, tais como o aumento de oferta de cursos lecionados em inglês, e a comunicação e a cooperação com as instituições de ensino superior na China. Assim, o plano de marketing desenvolvido apresenta diversas ações e estratégias, que visam melhorar a imagem do ISEG no mercado chinês, aumentar a sua notoriedade, incrementar o número das inscrições de alunos chineses, etc.
For chineses students, the general knowledge for ISEG's is relatively low, mainly due to the two aspects: communication in the Chinese market and cooperation programs with HEIs in China. In the initial phase of exploring Chinese market, it is crucial for ISEG to understand the Chinese market and the profile of Chinese students, even their parents. The main objetivo for the present project is to explore the profile of Chinese students and their perception in terms of Portugal, through secondary data and the questionnaire for chinese students who are already attending undergraduate, masters and doctorate courses in Portugal. In order to understand the main strengths and weaknesses of ISEG compared with its competitors external and internal, a competition analysis is carried out. Based on that, we find out the main parts to be improved, such as: increase the number of courses taught in English, the communication and cooperation with higher education institutions in China. As a result, the Marketing Plan developed presents several actions and strategies, aimed at improving the image of ISEG in the Chinese market, increase its notoriety, and the enrollment of Chinese students, etc.
info:eu-repo/semantics/publishedVersion
7

Cull, Dominic. "ISPs IN THE MIDDLE." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/4595.

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8

Ulfskans, Niklas, and Christian Thorell. "ISPS : Vakten i Göteborgs oljehamn." Thesis, University of Kalmar, Kalmar Maritime Academy, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-241.

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Med anledning av ISPS- kodens inträdande 2004 och personliga erfarenheter från fartyg och skyddsvaktsarbete har vi valt att fördjupa oss i ämnet portvaktens arbetsuppgifter. Vad vi har observerat sedan tidigare är att den allmänna uppfattningen bland ombordanställda är att portvakten är i vägen och det tar lång tid att komma till sin arbetsplats på fartyget.

Detta är en deskriptiv uppsats, där vi gjort en kvalitativ studie som bygger på intervju med vaktpersonal. Intervjun är sedan jämförd med de regler som finns för vakten i porten. Vi har avgränsat oss till att undersöka Göteborgs hamn, då denna var först i Europa att införa ISPS. Vi har intervjuat Magnus Rosenqvist, gruppchef på G4S i Göteborgs hamn. Detta har vi sedan jämfört med vad sjöbefälsstudenter på Högskolan i Kalmar har för erfarenheter och uppfattningar.

Vakten ansvarar för tillträdet till hamnområdet. Anledningen varför kontrollerna är så höga är för att upprätthålla hamnskyddet, inte fartygsskyddet. Vakten har samma ISPS- utbildning som resterande hamnpersonal, den utbildning en väktare måste inneha, men i Göteborgs hamn måste man dessutom vara skyddsvakt.


In connection with the ISPS- code's arising in 2004 and personal experiences from ships and security guarding, we have selected to deepen ourselves in the matter the gatekeeper’s duties. We have observed already that the general view among the vessel’s apployes, that the gatekeeper is in the way and it takes a long time to get to the workplace onboard the ship.

This is a descriptive essay, where we have done a qualitative study that builds on interview with local security personnel. The interview is then compared with the rules that are for the security guard in the gate. We have delimited ourselves to examining Gothenburg's port, because this is the first port in Europe to introduce the ISPS- code. We have interviewed Magnus Rosenqvist, squad commander at G4S in Gothenburg’s port. This result is then compared with the experiences and thoughts of students at Kalmar Maritime Academy.

The security guards are responsible for the access to the port area. The reason why the controls are so high is in order to maintain the port’s protection, not the ship’s protection. The security guard has the same ISPS education that all port personnel have, the education a general security guard must hold, but in Gothenburg’s port a security guard also must have a “skyddsvakt’s” education.

9

Kunfermann, Andrea Christiana [Verfasser], Michael [Akademischer Betreuer] Groll, and Thomas [Akademischer Betreuer] Kiefhaber. "Structural and functional characterization of the non-mevalonate pathway enzymes IspC and IspD in complex with natural and synthetic ligands / Andrea Christiana Kunfermann. Gutachter: Michael Groll ; Thomas Kiefhaber. Betreuer: Michael Groll." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/104867732X/34.

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Chow, Alex. "Incompressible SPH (ISPH) on the GPU." Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/incompressible-sph-isph-on-the-gpu(b569f890-78f1-42c2-b9d4-7082b45f45c8).html.

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Incompressible free-surface flows involving highly complex and violent phenomena are of great importance to the engineering industry. Applications such as breaking-wave impacts, fluid-structure interaction, and sloshing tanks demand an accurate and noise-free pressure field, and require large-scale simulations involving millions of computation points. This thesis addresses the need with the novel use of a graphics processing unit (GPU) to accelerate the incompressible smoothed particle hydrodynamics (ISPH) method for highly non-linear and violent free-surface flows using millions of particles in three dimensions. Compared to other simulation techniques, ISPH is robust in predicting a highly accurate pressure field, through the solution of a pressure Poisson equation (PPE), whilst capturing the complex behaviour of violent free-surface flows. However, for large-scale engineering applications the solution of extremely large PPE matrix systems on a GPU presents multiple challenges: constructing a PPE matrix every time step on the GPU for moving particles, overcoming the GPU memory limitations, establishing a robust and accurate ISPH solid boundary condition suitable for parallel processing on the GPU, and exploiting fast linear algebra GPU libraries. A new GPU-accelerated ISPH algorithm is presented by converting the highly optimised weakly-compressible SPH (WCSPH) code DualSPHysics and combining it with the open-source ViennaCL linear algebra library for fast solutions of the ISPH PPE. The challenges are addressed with new methodologies: a parallel GPU algorithm for population of the PPE matrix, mixed precision storage and computation, and extension of an existing WCSPH boundary treatment for ISPH. Taking advantage of a GPU-based algebraic multigrid preconditioner for solving the PPE matrix required modification for ISPH's Lagrangian particle system. The new GPU-accelerated ISPH solver, Incompressible-DualSPHysics, is validated through a variety of demanding test cases and shown to achieve speed ups of up to 25.3 times and 8.1 times compared to single and 16-threaded CPU computations respectively. The influence of free-surface fragmentation on the PPE matrix solution time with different preconditioners is also investigated. A profiling study shows the new code to concentrate the GPU's processing power on solving the PPE. Finally, a real-engineering 3-D application of breaking focused-wave impacting a surface-piercing cylindrical column is simulated with ISPH for the first time. Extensions to the numerical model are presented to enhance the accuracy of simulating wave-structure impact. Simulations involving over 5 million particles show agreement with experimental data. The runtimes are similar to volume-of-fluid and particle-in-cell solvers running on 8 and 80 processors respectively. The 3-D model enables post-processing analysis of the wave mechanics around the cylinder. This study provides a substantial step for ISPH. Incompressible-DualSPHysics achieves resolutions previously too impractical for a single device allowing for the simulation of many industrial free-surface hydrodynamic applications.
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Книги з теми "IspG":

1

International Symposium on Photonic Glass (2002 Shanghai, China). Photonic glass (ISPG 2002): International Symposium on Photonic Glass : 14-17 October, 2002, Shanghai, China. Edited by Zhu Congshan, Society of Photo-optical Instrumentation Engineers., and Shanghai guang xue jing mi ji xie yan jiu suo. Bellingham, Wash: SPIE, 2003.

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2

Makanin, Vladimir. ISpug. Moskva: Geleos, 2006.

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3

Makanin, Vladimir. Ispug: Roman. Moskva: Geleos, 2006.

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4

Azevedo, Joseph A. ISPF: The strategic dialog manager. New York, NY: Intertext Publications, 1989.

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5

Promotion, Institute of Sales, ed. ISP awards. [S. l.]: Institute of Sales Promotion, 1992.

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6

Valério, Nuno, António Romão, and Manuel Brandão Alves. Em directo do ISEG. Oeiras: Celta Editora, 2004.

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7

Leĭbgrad, S. M. Proba na ispug: Stikhi. Samara: T͡S︡entr "Inform-video-press" predprii͡a︡tii͡a︡ "Samaratransgaz", 1993.

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8

ISP, Workshop (2nd 1991 Chemnitz Germany). ISP '91, interaktive Datenanalyse mit ISP: Tagungsband des 2. ISP Workshops, TU Chemnitz. Essen: Westarp Wissenschaften, 1992.

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9

Huston, Geoff. ISP survival guide: Strategies for running a competitive ISP. New York: Wiley, 1999.

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10

Huston, Geoff. ISP survival guide: Strategies for running a competitive ISP. New York: Wiley, 1999.

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Частини книг з теми "IspG":

1

Andrzej, Siemiński. "Selecting ISPs." In Transactions on Computational Collective Intelligence IV, 177–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21884-2_5.

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2

Bonati, Marco, and Michael Ashe. "ISPI Software." In Scientific Detectors for Astronomy, 427–30. Dordrecht: Springer Netherlands, 2004. http://dx.doi.org/10.1007/1-4020-2527-0_54.

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3

Widyatmoko, Bondan. "Interests Arrangement in the Implementation of Indonesian Sustainable Palm Oil Certification: Case Study of Sari Makmur Palm Oil Smallholders in Riau Province." In Global Environmental Studies, 197–222. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0906-3_11.

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AbstractThe implementation of the Indonesian Sustainable Palm Oil (ISPO) certification remains unsettled nearly a decade since its introduction in 2011. Only a small number of palm oil companies and smallholders have been ISPO certified. Palm oil smallholders became the target of ISPO certification because of their significant contribution to the Indonesian palm oil industry. This study aims to analyze the slow ISPO implementation process at the smallholder level by using a polycentric governance framework, which views the ISPO’s overarching rules as changing the relationship between companies and smallholders toward sustainable management. This study examines a smallholder’s ISPO implementation in Sari Makmur. This smallholder became a pilot project site for the smallholder ISPO certification in 2011; however, it has still not been certified. This study reveals that the recurring problem of land swaps and the expectations of being certified have complicated the fulfillment process of legal documents for ISPO certification. Nevertheless, smallholders and companies are in the process of delineating their interests toward defining their physical boundaries for sustainable palm oil production.
4

Corsbie-Massay, Charisse L’Pree. "Dial-up ISPs." In 20th Century Media and the American Psyche, 162–78. London ; New York : Routledge, 2020.: Routledge, 2020. http://dx.doi.org/10.4324/9780203702352-13.

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5

van den Berg, Frans, and Udo Wolf. "Iliosacralgelenk (ISG)." In Manuelle Therapie. Sichere und effektive Manipulationstechniken, 141–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56021-7_8.

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6

Kramer, Johannes. "Internationale Sozialpolitik (ISP)." In Handwörterbuch Internationale Politik, 244–49. Wiesbaden: VS Verlag für Sozialwissenschaften, 1986. http://dx.doi.org/10.1007/978-3-663-20299-8_36.

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7

Ng, Adolf K. Y., and George K. Vaggelas. "Port Security: The ISPS Code." In The Blackwell Companion to Maritime Economics, 674–700. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781444345667.ch33.

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8

Hartmann, Lukas, Matthias Marx, and Eva Schedel. "Wie vertrauenswürdig können ISPs sein?" In DuD-Fachbeiträge, 225–47. Wiesbaden: Springer Fachmedien Wiesbaden, 2018. http://dx.doi.org/10.1007/978-3-658-23727-1_13.

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9

E. Ricart-Costa, Joan, Brian Subirana, and Josep Valor-Sabatier. "Local Loop, ISPs and IAPs." In Sources of Information Value, 43–62. London: Palgrave Macmillan UK, 2004. http://dx.doi.org/10.1057/9780230512948_3.

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10

Nam, Gi-Joon, Charles J. Alpert, and Paul G. Villarrubia. "ISPD 2005/2006 Placement Benchmarks." In Series on Integrated Circuits and Systems, 3–12. Boston, MA: Springer US, 2007. http://dx.doi.org/10.1007/978-0-387-68739-1_1.

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Тези доповідей конференцій з теми "IspG":

1

Maranhão, Robson, Marcelo Marinho, and Hermano De Moura. "Model for Assessing the Maturity Level of the Information Security Risk Management Process." In XIV Simpósio Brasileiro de Qualidade de Software. Sociedade Brasileira de Computação - SBC, 2015. http://dx.doi.org/10.5753/sbqs.2015.15210.

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Nowadays, innovation is one of the keys to success in organization and project management has become an important way to improve it. Innovative Software Projects (ISP) have a high level of uncertainty andcomplexity, so we need a specific approach to manage those threats. This paper presents a systematic literature review of Innovative Software Project Management (ISPM), helping to identify the factors that affect ISP and their management such as tools, techniques, processes, practices, organizational capabilities and IT assets; and how managers can prepare themselves for the challenges of their innovative projects. This paper aims to contribute to the improvement and success of project management in organizations.
2

E. Quincozes, Vagner, Daniel Temp, Silvio E. Quincozes, Diego Kreutz, and Rodrigo B. Mansilha. "Sistema para Autenticação entre Clientes, Técnicos e ISPs." In XVIII Escola Regional de Redes de Computadores. Sociedade Brasileira de Computação - SBC, 2020. http://dx.doi.org/10.5753/errc.2020.15199.

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O processo de suporte dos Internet Service Providers (ISPs) regionais ainda costuma utilizar protocolos frágeis de autenticação, como as carteirinhas físicas (ou virtuais) baseadas em dados estáticos não autenticáveis. Essas carteirinhas podem ser facilmente roubadas, clonadas, ou reproduzidas, comprometendo o processo de autenticação entre as entidades envolvidas com suporte técnico, presencial e remoto, do ISP (clientes, técnicos, e gestores). Neste trabalho, propomos um sistema composto por mecanismos e protocolos para autenticar e identificar de forma segura as referidas entidades. A ferramenta Scyther foi utilizada para realizar uma verificação automática do protocolo proposto.
3

Radulescu, Ion Razvan, Emilia Visileanu, Razvan Scarlat, Marian Catalin Grosu, Ana Dias, Benny Malengier, Zoran Stjepanovic, Mirela Blaga, and Radek Polansky. "Impact of Intensive Study Programs on Higher Education Students in the Field of Design and Modelling of Textile Materials." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.vi.3.

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The knowledge of software for design and modelling of textiles offers a competitive advantage within the world of work for young textile creatives. The Erasmus+ project OptimTex – “Software tools for textile creatives” has created a large set of educational materials and the corresponding e-learning resources in this competitive domain. Six educational modules, one Moodle e-learning platform with courses in six national languages, one e-learning instrument for quick access to the content and one glossary of terms were implemented during the two-year’s project 2020-2022 (www.optimtex.eu). Two Intensive Study Programs (ISPs) of five days were already organized by the project’s partners: one virtual ISP with the host Technical University of Iasi and one mobility ISP with the host University of Maribor. A total number of 27 students and 15 lecturers participated in the first ISP and a total number of 17 students and 12 lecturers participated in the second ISP. The six modules for Design and Modelling of woven structures, knitted structures, virtual prototyping of clothing, embroidered e-textiles, design of experiments, and TechTransfer had a high impact on the students. The impact was measured by feedback questionnaires and the interest in e-learning resources by the number of accesses (www.advan2tex.eu/portal/). This paper presents the impact of the educational materials on Higher Education students in relation to the envisaged objectives of the project.
4

Quincozes, Vagner E., Silvio E. Quincozes, Diego Kreutz, and Rodrigo B. Mansilha. "Identifica ISP: Autenticação Mútua entre Múltiplas Entidades para Serviços de Suporte Técnico Prestados por ISPs." In Anais Estendidos do Simpósio Brasileiro de Segurança da Informação e de Sistemas Computacionais. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/sbseg_estendido.2021.17336.

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Os Internet Service Providers (ISPs) ainda utilizam mecanismos frágeis para autenticação e identificação entre as entidades envolvidas em suporte técnico especializado (i.e., clientes, técnicos e gestores). Tais mecanismos geram insegurança aos usuários, pois costumam adotar dados estáticos não autenticáveis (e.g., CPF em cartões físicos ou virtuais) que podem ser facilmente roubados, clonados ou reproduzidos. Neste trabalho, propomos um sistema para autenticação e identificação de clientes, técnicos e gestores de ISP, composto por: (i) um aplicativo para dispositivos móveis suportado por um sistema de back-end e (ii) a implementação de protocolos de segurança que oferecem serviços de identificação e autenticação. Uma demonstração da aplicação ilustra o modo de utilização do sistema. Uma avaliação conceitual dos serviços de segurança, amparada pela análise dos protocolos por meio da ferramenta Scyther, sustenta a segurança provida pelo sistema.
5

Quincozes, Vagner E., Silvio E. Quincozes, Diego Kreutz, and Rodrigo B. Mansilha. "Identifica ISP: Autenticação Mútua entre Múltiplas Entidades para Serviços de Suporte Técnico Prestados por ISPs." In Anais Estendidos do Simpósio Brasileiro de Segurança da Informação e de Sistemas Computacionais. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/sbseg_estendido.2021.17336.

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Анотація:
Os Internet Service Providers (ISPs) ainda utilizam mecanismos frágeis para autenticação e identificação entre as entidades envolvidas em suporte técnico especializado (i.e., clientes, técnicos e gestores). Tais mecanismos geram insegurança aos usuários, pois costumam adotar dados estáticos não autenticáveis (e.g., CPF em cartões físicos ou virtuais) que podem ser facilmente roubados, clonados ou reproduzidos. Neste trabalho, propomos um sistema para autenticação e identificação de clientes, técnicos e gestores de ISP, composto por: (i) um aplicativo para dispositivos móveis suportado por um sistema de back-end e (ii) a implementação de protocolos de segurança que oferecem serviços de identificação e autenticação. Uma demonstração da aplicação ilustra o modo de utilização do sistema. Uma avaliação conceitual dos serviços de segurança, amparada pela análise dos protocolos por meio da ferramenta Scyther, sustenta a segurança provida pelo sistema.
6

Noroozian, Arman, Elsa Turcios Rodriguez, Elmer Lastdrager, Takahiro Kasama, Michel Van Eeten, and Carlos H. Ganan. "Can ISPs Help Mitigate IoT Malware? A Longitudinal Study of Broadband ISP Security Efforts." In 2021 IEEE European Symposium on Security and Privacy (EuroS&P). IEEE, 2021. http://dx.doi.org/10.1109/eurosp51992.2021.00031.

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7

Matsuda, Kazuhito, Go Hasegawa, and Masayuki Murata. "Cooperative cache sharing among ISPs for reducing inter-ISP transit cost in content-centric networking." In 2014 International Conference on Information Networking (ICOIN). IEEE, 2014. http://dx.doi.org/10.1109/icoin.2014.6799693.

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8

Liao, Qi, Zhen Li, and Aaron Striegel. "Is more P2P always bad for ISPs? An analysis of P2P and ISP business models." In 2014 23rd International Conference on Computer Communication and Networks (ICCCN). IEEE, 2014. http://dx.doi.org/10.1109/icccn.2014.6911841.

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9

Zhang, Zheng, Ying Zhang, Y. Charlie Hu, Z. Morley Mao, and Randy Bush. "Ispy." In the ACM SIGCOMM 2008 conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1402958.1402996.

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10

Raguram, Rahul, Andrew M. White, Dibyendusekhar Goswami, Fabian Monrose, and Jan-Michael Frahm. "iSpy." In the 18th ACM conference. New York, New York, USA: ACM Press, 2011. http://dx.doi.org/10.1145/2046707.2046769.

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Звіти організацій з теми "IspG":

1

Redding, Kevin, and Thomas Beatty. Joint Conference Support (ISPP and ICMP). Office of Scientific and Technical Information (OSTI), November 2020. http://dx.doi.org/10.2172/1706736.

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2

Reddy, S. ISPE: A knowledge-based system for fluidization studies. Office of Scientific and Technical Information (OSTI), January 1991. http://dx.doi.org/10.2172/7173674.

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3

Gates, Carrie, Josh McNutt, Joseph B. Kadane, and Marc Kellner. Detecting Scans at the ISP Level. Fort Belvoir, VA: Defense Technical Information Center, April 2006. http://dx.doi.org/10.21236/ada448156.

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4

Keliiaa, Curtis M. Tribal Telecom/ISP IPv6 Business Planning. Office of Scientific and Technical Information (OSTI), February 2016. http://dx.doi.org/10.2172/1560991.

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5

Sullivan, John P. X-ray simulation algorithms used in ISP. Office of Scientific and Technical Information (OSTI), July 2016. http://dx.doi.org/10.2172/1291276.

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6

Reddy, S. ISPE: A knowledge-based system for fluidization studies. 1990 Annual report. Office of Scientific and Technical Information (OSTI), January 1991. http://dx.doi.org/10.2172/10185464.

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7

Pareira, Samuel. Mencapai Keterlacakan Minyak Sawit Indonesia yang Menyeluruh melalui Harmonisasi ISPO-RSPO. Jakarta, Indonesia: Center for Indonesian Policy Studies, 2023. http://dx.doi.org/10.35497/560889.

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8

Chen, Xingji. Discovering and Characterizing Interdomain Links Between Access ISPs and Netflix CDN. Ames (Iowa): Iowa State University, January 2019. http://dx.doi.org/10.31274/cc-20240624-559.

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9

Asadullah, S., A. Ahmed, C. Popoviciu, P. Savola, and J. Palet. ISP IPv6 Deployment Scenarios in Broadband Access Networks. RFC Editor, January 2007. http://dx.doi.org/10.17487/rfc4779.

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10

Pareira, Samuel. Achieving Indonesian Palm Oil Farm-to-Table Traceability through ISPO-RSPO Harmonization. Jakarta, Indonesia: Center for Indonesian Policy Studies, 2023. http://dx.doi.org/10.35497/560227.

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