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Статті в журналах з теми "Intégration de données de peptidomique"
Boussaid, Omar, Fadila Lafaye, Jérôme Darmont, and Sabine Rabaseda. "Vers l'entreposage des données complexes. Structuration, intégration et analyse." Ingénierie des systèmes d'information 8, no. 5-6 (December 24, 2003): 79–107. http://dx.doi.org/10.3166/isi.8.5-6.79-107.
Повний текст джерелаVidal, Alain, Solène Laloux, and Damien Lepoutre. "Analyse des systèmes d'information et intégration des données spatialisées." La Houille Blanche, no. 8 (December 1996): 55–60. http://dx.doi.org/10.1051/lhb/1996088.
Повний текст джерелаDrolet, Gaëtan. "La bibliothèque universitaire québécoise à l’aube des fichiers de données numériques." Documentation et bibliothèques 38, no. 1 (February 11, 2015): 15–22. http://dx.doi.org/10.7202/1028558ar.
Повний текст джерелаDevignes, Marie-Dominique, André Schaaff, and Malika Smaïl. "Collecte et intégration de données biologiques hétérogènes sur le web." Ingénierie des systèmes d'information 7, no. 1-2 (April 24, 2002): 45–61. http://dx.doi.org/10.3166/isi.7.1-2.45-61.
Повний текст джерелаDelahaye-Duriez, Andrée, Brigitte Benzacken, Michael Johnson, and Enrico Petretto. "Intégration des données de RNAseq sur cellule unique du cerveau." Morphologie 101, no. 335 (December 2017): 240–41. http://dx.doi.org/10.1016/j.morpho.2017.07.006.
Повний текст джерелаRossille, D., S. Bayat, A. Burgun, M. C. Béné, and T. Fest. "Intégration de données en recherche clinique : étude sur les lymphomes." Revue d'Épidémiologie et de Santé Publique 56, no. 1 (April 2008): 50–51. http://dx.doi.org/10.1016/j.respe.2008.02.101.
Повний текст джерелаGutzwiller, F. "Méthodologie des enquêtes de santé et intégration des données sanitaires." Sozial- und Präventivmedizin SPM 30, no. 2 (March 1985): 66. http://dx.doi.org/10.1007/bf02083046.
Повний текст джерелаCoulibaly, L., and Q. H. J. Gwyn. "Intégration de données d'images satellitaires optiques et radars et de données topographiques pour la cartographie géomorphologique." Canadian Journal of Remote Sensing 31, no. 6 (December 2005): 439–49. http://dx.doi.org/10.5589/m05-028.
Повний текст джерелаBERNIER, M., J. P. FORTIN, Y. GAUTHIER, C. CORBANE, J. SOMMA, and J. P. DEDIEU. "Intégration de données satellitaires à la modélisation hydrologique du Mont Liban." Hydrological Sciences Journal 48, no. 6 (December 2003): 999–1012. http://dx.doi.org/10.1623/hysj.48.6.999.51428.
Повний текст джерелаD’Haene, Nicky, Oriane Blanchard, Nancy De Nève, Julien Evens, Marie Le Mercier, and Isabelle Salmon. "Intégration des données de la biologie moléculaire au diagnostic anatomopathologique des gliomes." Morphologie 99, no. 326 (September 2015): 92–93. http://dx.doi.org/10.1016/j.morpho.2015.07.052.
Повний текст джерелаДисертації з теми "Intégration de données de peptidomique"
Suwareh, Ousmane. "Modélisation de la pepsinolyse in vitro en conditions gastriques et inférence de réseaux de filiation de peptides à partir de données de peptidomique." Electronic Thesis or Diss., Rennes, Agrocampus Ouest, 2022. https://tel.archives-ouvertes.fr/tel-04059711.
Повний текст джерелаAddressing the current demographic challenges, “civilization diseases” and the possible depletion of food resources, require optimization of food utilization and adapting their conception to the specific needs of each target population. This requires a better understanding of the different stages of the digestion process. In particular, how proteins are hydrolyzed is a major issue, due to their crucial role in human nutrition. However, the probabilistic laws governing the action of pepsin, the first protease to act in the gastrointestinal tract, are still unclear.In a first approach based on peptidomic data, we demonstrate that the hydrolysis by pepsin of a peptidebond depends on the nature of the amino acid residues in its large neighborhood, but also on physicochemical and structural variables describing its environment. In a second step, and considering the physicochemical environment at the peptide level, we propose a nonparametric model of the hydrolysis by pepsin of these peptides, and an Expectation-Maximization type estimation algorithm, offering novel perspectives for the valorization of peptidomic data. In this dynamic approach, we integrate the peptide kinship network into the estimation procedure, which leads to a more parsimonious model that is also more relevant regarding biological interpretations
Le, Béchec Antony. "Gestion, analyse et intégration des données transcriptomiques." Rennes 1, 2007. http://www.theses.fr/2007REN1S051.
Повний текст джерелаAiming at a better understanding of diseases, transcriptomic approaches allow the analysis of several thousands of genes in a single experiment. To date, international standard initiatives have allowed the utilization of large quantity of data generated using transcriptomic approaches by the whole scientific community, and a large number of algorithms are available to process and analyze the data sets. However, the major challenge remaining to tackle is now to provide biological interpretations to these large sets of data. In particular, their integration with additional biological knowledge would certainly lead to an improved understanding of complex biological mechanisms. In my thesis work, I have developed a novel and evolutive environment for the management and analysis of transcriptomic data. Micro@rray Integrated Application (M@IA) allows for management, processing and analysis of large scale expression data sets. In addition, I elaborated a computational method to combine multiple data sources and represent differentially expressed gene networks as interaction graphs. Finally, I used a meta-analysis of gene expression data extracted from the literature to select and combine similar studies associated with the progression of liver cancer. In conclusion, this work provides a novel tool and original analytical methodologies thus contributing to the emerging field of integrative biology and indispensable for a better understanding of complex pathophysiological processes
Saïs, Fatiha. "Intégration sémantique de données guidée par une ontologie." Paris 11, 2007. http://www.theses.fr/2007PA112300.
Повний текст джерелаThis thesis deals with semantic data integration guided by an ontology. Data integration aims at combining autonomous and heterogonous data sources. To this end, all the data should be represented according to the same schema and according to a unified semantics. This thesis is divided into two parts. In the first one, we present an automatic and flexible method for data reconciliation with an ontology. We consider the case where data are represented in tables. The reconciliation result is represented in the SML format which we have defined. Its originality stems from the fact that it allows representing all the established mappings but also information that is imperfectly identified. In the second part, we present two methods of reference reconciliation. This problem consists in deciding whether different data descriptions refer to the same real world entity. We have considered this problem when data is described according to the same schema. The first method, called L2R, is logical: it translates the schema and the data semantics into a set of logical rules which allow inferring correct decisions both of reconciliation and no reconciliation. The second method, called N2R, is numerical. It translates the schema semantics into an informed similarity measure used by a numerical computation of the similarity of the reference pairs. This computation is expressed in a non linear equation system solved by using an iterative method. Our experiments on real datasets demonstrated the robustness and the feasibility of our approaches. The solutions that we bring to the two problems of reconciliation are completely automatic and guided only by an ontology
Delanaux, Rémy. "Intégration de données liées respectueuse de la confidentialité." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1303.
Повний текст джерелаIndividual privacy is a major and largely unexplored concern when publishing new datasets in the context of Linked Open Data (LOD). The LOD cloud forms a network of interconnected and publicly accessible datasets in the form of graph databases modeled using the RDF format and queried using the SPARQL language. This heavily standardized context is nowadays extensively used by academics, public institutions and some private organizations to make their data available. Yet, some industrial and private actors may be discouraged by potential privacy issues. To this end, we introduce and develop a declarative framework for privacy-preserving Linked Data publishing in which privacy and utility constraints are specified as policies, that is sets of SPARQL queries. Our approach is data-independent and only inspects the privacy and utility policies in order to determine the sequence of anonymization operations applicable to any graph instance for satisfying the policies. We prove the soundness of our algorithms and gauge their performance through experimental analysis. Another aspect to take into account is that a new dataset published to the LOD cloud is indeed exposed to privacy breaches due to the possible linkage to objects already existing in the other LOD datasets. In the second part of this thesis, we thus focus on the problem of building safe anonymizations of an RDF graph to guarantee that linking the anonymized graph with any external RDF graph will not cause privacy breaches. Given a set of privacy queries as input, we study the data-independent safety problem and the sequence of anonymization operations necessary to enforce it. We provide sufficient conditions under which an anonymization instance is safe given a set of privacy queries. Additionally, we show that our algorithms are robust in the presence of sameAs links that can be explicit or inferred by additional knowledge. To conclude, we evaluate the impact of this safety-preserving solution on given input graphs through experiments. We focus on the performance and the utility loss of this anonymization framework on both real-world and artificial data. We first discuss and select utility measures to compare the original graph to its anonymized counterpart, then define a method to generate new privacy policies from a reference one by inserting incremental modifications. We study the behavior of the framework on four carefully selected RDF graphs. We show that our anonymization technique is effective with reasonable runtime on quite large graphs (several million triples) and is gradual: the more specific the privacy policy is, the lesser its impact is. Finally, using structural graph-based metrics, we show that our algorithms are not very destructive even when privacy policies cover a large part of the graph. By designing a simple and efficient way to ensure privacy and utility in plausible usages of RDF graphs, this new approach suggests many extensions and in the long run more work on privacy-preserving data publishing in the context of Linked Open Data
Megdiche, Bousarsar Imen. "Intégration holistique et entreposage automatique des données ouvertes." Thesis, Toulouse 3, 2015. http://www.theses.fr/2015TOU30214/document.
Повний текст джерелаStatistical Open Data present useful information to feed up a decision-making system. Their integration and storage within these systems is achieved through ETL processes. It is necessary to automate these processes in order to facilitate their accessibility to non-experts. These processes have also need to face out the problems of lack of schemes and structural and sematic heterogeneity, which characterize the Open Data. To meet these issues, we propose a new ETL approach based on graphs. For the extraction, we propose automatic activities performing detection and annotations based on a model of a table. For the transformation, we propose a linear program fulfilling holistic integration of several graphs. This model supplies an optimal and a unique solution. For the loading, we propose a progressive process for the definition of the multidimensional schema and the augmentation of the integrated graph. Finally, we present a prototype and the experimental evaluations
Grison, Thierry. "Intégration de schémas de bases de données entité-association." Dijon, 1994. http://www.theses.fr/1994DIJOS005.
Повний текст джерелаHamdoun, Khalfallah Sana. "Construction d'entrepôts de données par intégration de sources hétérogènes." Paris 13, 2006. http://www.theses.fr/2006PA132039.
Повний текст джерелаThis work describes the construction of a data warehouse by the integration of heterogeneous data. These latter could be structured, semi-structured or unstructured. We propose a theoretical approach based on an integration environment definition. This environment is formed by data sources and inter-schema relationships between these sources ( equivalence and strict order relations). Our approach is composed of five steps allowing data warehouse component choice, global schema generation and construction of data warehouse views. Multidimensional schemas are also proposed. All the stages proposed in this work are implemented by the use of a functional prototype (using SQL and Xquery). Keywords Data Integration, data warehouses, heterogeneous data, inter-schema relationships, Relational, Object-relational, XML, SQL, Xquery
Lemoine, Frédéric. "Intégration, interrogation et analyse de données de génomique comparative." Paris 11, 2008. http://www.theses.fr/2008PA112180.
Повний текст джерелаOur work takes place within the « Microbiogenomics » project. Microbiogenomics aims at building a genomic prokaryotic data warehouse. This data warehouse gathers numerous data currently dispersed, in order to improve functional annotation of bacterial genomes. Within this project, our work contains several facets. The first one focuses mainly on the analyses of biological data. We are particularly interested in the conservation of gene order during the evolution of prokaryotic genomes. To do so, we designed a computational pipeline aiming at detecting the areas whose gene order is conserved. We then studied the relative evolution of the proteins coded by genes that are located in conserved areas, in comparison with the other proteins. This data were made available through the SynteView synteny visualization tool (http://www. Synteview. U-psud. Fr). Moreover, to broaden the analysis of these data, we need to cross them with other kinds of data, such as pathway data. These data, often dispersed and heterogeneous, are difficult to query. That is why, in a second step, we were interested in querying the Microbiogenomics data warehouse. We designed an architecture and some algorithms to query the data warehouse, while keeping the different points of view given by the sources. These algorithms were implemented in GenoQuery (http://www. Lri. Fr/~lemoine/GenoQuery), a prototype querying module adapted to a genomic data warehouse
Lozano, Espinosa Rafael. "Intégration de données vidéo dans un SGBD à objets." Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10050.
Повний текст джерелаJautzy, Olivier. "Intégration de sources de données hétérogènes : Une approche langage." Marne-la-vallée, ENPC, 2000. http://www.theses.fr/2000ENPC0002.
Повний текст джерелаКниги з теми "Intégration de données de peptidomique"
Millet, Pierre. Intégration voix et données: Principes et concepts. Paris: Masson, 1988.
Знайти повний текст джерелаMichael, Catinat, Jacquemin Alex, and Cecchini Paolo, eds. 1992, le défi: Nouvelles données économiques de l'Europe sans frontières. Paris: Flammarion, 1988.
Знайти повний текст джерелаRode, Gilles. Handicap, médecine physique et réadaptation, guide pratique. Montrouge: Édition Xavier Montauban, 2003.
Знайти повний текст джерелаCarina, Roldán María, and ebrary Inc, eds. Pentaho data integration 4 cookbook: Over 70 recipes to solve ETL problems using Pentaho Kettle. Birmingham, U.K: Packt Pub., 2011.
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Знайти повний текст джерелаЧастини книг з теми "Intégration de données de peptidomique"
WACK, Maxime. "Entrepôts de données cliniques." In Intégration de données biologiques, 9–31. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch1.
Повний текст джерелаDAMERON, Olivier. "Méthodes du Web sémantique pour l’intégration de données en sciences de la vie." In Intégration de données biologiques, 33–61. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch2.
Повний текст джерелаMARIETTE, Jérôme, and Nathalie VIALANEIX. "Des noyaux pour les omiques." In Intégration de données biologiques, 165–210. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch6.
Повний текст джерелаGUINOT, Florent, Marie SZAFRANSKI, and Christophe AMBROISE. "Compression structurée de l’information génétique et étude d’association pangénomique par modèles additifs." In Intégration de données biologiques, 129–63. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch5.
Повний текст джерелаLÉVY-LEDUC, Céline, Marie PERROT-DOCKÈS, Gwendal CUEFF, and Loïc RAJJOU. "Sélection de variables dans le modèle linéaire général : application à des approches multiomiques pour étudier la qualité des graines." In Intégration de données biologiques, 101–28. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch4.
Повний текст джерелаCOHEN-BOULAKIA, Sarah, and Frédéric LEMOINE. "Workflows d’intégration de données bioinformatiques." In Intégration de données biologiques, 63–97. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch3.
Повний текст джерелаDÉJEAN, Sébastien, and Kim-Anh LÊ CAO. "Modèles multivariés pour l’intégration de données et la sélection de biomarqueurs dans les données omiques." In Intégration de données biologiques, 211–69. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9030.ch7.
Повний текст джерелаMath, François, Jean-Pierre Kahn, and Jean-Pierre Vignal. "Chapitre 5. Intégration des données sensorielles par le cerveau." In Neurosciences cliniques, 231–303. De Boeck Supérieur, 2008. http://dx.doi.org/10.3917/dbu.math.2008.01.0231.
Повний текст джерелаYERGEAU, Michel, Christian PRÉVOST, Bertin Goze BÉNIÉ, and Ferdinand BONN. "Intégration de données multisources pour la gestion des ressources en eau au Sahel." In Télédétection de l'environnement dans l'espace francophone, 457–78. Presses de l'Université du Québec, 2011. http://dx.doi.org/10.2307/j.ctv18pgwp2.39.
Повний текст джерела"Intégration des activités sur le terrain à l’aide de GPS et de données télédétectées." In Etudes méthodologiques (Ser. F), 89–116. UN, 2009. http://dx.doi.org/10.18356/dc73afd3-fr.
Повний текст джерелаТези доповідей конференцій з теми "Intégration de données de peptidomique"
Antoni, M., and M. Houel. "Intégration de données continues au sein d’une méthode de validation formelle par approche événementielle." In Congrès Lambda Mu 19 de Maîtrise des Risques et Sûreté de Fonctionnement, Dijon, 21-23 Octobre 2014. IMdR, 2015. http://dx.doi.org/10.4267/2042/56143.
Повний текст джерелаDufau, J., H. Galley, and J. C. Mangin. "Intégration d'un modèle d'évaluation technique et économique de gros-cuvre de bâtiment dans un système de CAO utilisant un système de gestion de base de données réseau." In Colloque CAO et Robotique en Architecture et BTP (3rd International Symposium on Automation and Robotics in Construction). Paris: Hermes, 1986. http://dx.doi.org/10.22260/isarc1986/0019.
Повний текст джерелаЗвіти організацій з теми "Intégration de données de peptidomique"
Toutin, Th. Intégration de données multisources: comparaison de méthodes géometriques et radiométriques. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1995. http://dx.doi.org/10.4095/218023.
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