Добірка наукової літератури з теми "In vitro antithrombotic properties"
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Статті в журналах з теми "In vitro antithrombotic properties"
Vasconcelos, Ariana, Isabela Sucupira, Alessandra Guedes, Ismael Queiroz, Flavia Frattani, Roberto Fonseca, and Vitor Pomin. "Anticoagulant and Antithrombotic Properties of Three Structurally Correlated Sea Urchin Sulfated Glycans and Their Low-Molecular-Weight Derivatives." Marine Drugs 16, no. 9 (August 30, 2018): 304. http://dx.doi.org/10.3390/md16090304.
Повний текст джерелаTsoupras, Alexandros, Ronan Lordan, Katie Shiels, Sushanta Saha, Constantina Nasopoulou, and Ioannis Zabetakis. "In Vitro Antithrombotic Properties of Salmon (Salmo salar) Phospholipids in a Novel Food-Grade Extract." Marine Drugs 17, no. 1 (January 18, 2019): 62. http://dx.doi.org/10.3390/md17010062.
Повний текст джерелаMerton, R. E., and D. P. Thomas. "Experimental Studies on the Relative Efficacy of Dermatan Sulphate and Heparin as Antithrombotic Agents." Thrombosis and Haemostasis 58, no. 03 (1987): 839–42. http://dx.doi.org/10.1055/s-0038-1646001.
Повний текст джерелаLordan, Ronan, Eoin O’Keeffe, Darren Dowling, Michael Mullally, Hannah Heffernan, Alexandros Tsoupras, and Ioannis Zabetakis. "The in vitro antithrombotic properties of ale, lager, and stout beers." Food Bioscience 28 (April 2019): 83–88. http://dx.doi.org/10.1016/j.fbio.2019.01.012.
Повний текст джерелаNestele, Jeremy A., Anne-Katrin Rohlfing, Valerie Dicenta, Alexander Bild, Daniela Eißler, Frederic Emschermann, Marcel Kremser, et al. "Characterization of GPVI- or GPVI-CD39-Coated Nanoparticles and Their Impact on In Vitro Thrombus Formation." International Journal of Molecular Sciences 23, no. 1 (December 21, 2021): 11. http://dx.doi.org/10.3390/ijms23010011.
Повний текст джерелаChung, Amy, Frederick A. Ofosu, and Morris A. Blajchman. "The Antithrombotic Properties of Human Prothrombin Fragment 1.2 in Mice." Thrombosis and Haemostasis 63, no. 03 (1990): 413–16. http://dx.doi.org/10.1055/s-0038-1645057.
Повний текст джерелаSchwarz, Richard P., Jean-Claude P. Becker, R. Lynn Brooks, Marcie J. Hursting, James L. Joffrion, Gary D. Knappenberger, Timothy P. Kogan, Patricia W. Kogan, and Anthony A. McKinney. "State-of-the-Art Review: The Preclinical and Clinical Pharmacology of Novastan (Argatroban): A Small-Molecule, Direct Thrombin Inhibitor." Clinical and Applied Thrombosis/Hemostasis 3, no. 1 (January 1997): 1–15. http://dx.doi.org/10.1177/107602969700300101.
Повний текст джерелаBoulaftali, Yacine, Frédéric Adam, Laurence Venisse, Véronique Ollivier, Benjamin Richard, Sabrina Taieb, Denis Monard, et al. "Anticoagulant and antithrombotic properties of platelet protease nexin-1." Blood 115, no. 1 (January 7, 2010): 97–106. http://dx.doi.org/10.1182/blood-2009-04-217240.
Повний текст джерелаSie, P., D. Dupouy, C. Caranobe, M. Petitou, and B. Boneu. "Antithrombotic properties of a dermatan sulfate hexadecasaccharide fractionated by affinity for heparin cofactor II." Blood 81, no. 7 (April 1, 1993): 1771–77. http://dx.doi.org/10.1182/blood.v81.7.1771.1771.
Повний текст джерелаSie, P., D. Dupouy, C. Caranobe, M. Petitou, and B. Boneu. "Antithrombotic properties of a dermatan sulfate hexadecasaccharide fractionated by affinity for heparin cofactor II." Blood 81, no. 7 (April 1, 1993): 1771–77. http://dx.doi.org/10.1182/blood.v81.7.1771.bloodjournal8171771.
Повний текст джерелаДисертації з теми "In vitro antithrombotic properties"
Aggarwal, Rajesh Kumar. "The antithrombotic properties of polymer-coated, drug eluting coronary stents." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34296.
Повний текст джерелаMnonopi, Nandipha Olivia. "In vitro testing to investigate the anticoagulant/antithrombotic and antidiabetic biological activity of Leonotis Leonurus." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/693.
Повний текст джерелаHartley, Richard William. "The development of an in-vivo method for assessing the antithrombotic properties of pharmaceutical compounds." Thesis, Loughborough University, 1989. https://dspace.lboro.ac.uk/2134/12084.
Повний текст джерелаLai, Benjamin Fook Lun. "Bioactive polymers : a comparative study on the antithrombotic properties of soluble polymers and surface grafted polymers." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/20871.
Повний текст джерелаTravers, M. "In vitro and clinical investigation of blood-membrane interactions : Influence on platelets and the immune system of membrane structure and antithrombotic agents." Thesis, University of Strathclyde, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382445.
Повний текст джерелаHuddie, P. L. "The properties of pituitary cells in vitro." Thesis, University of Newcastle Upon Tyne, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379245.
Повний текст джерелаSousa, Hiran Reis. "Investigação da atividade anti-agregante plaquetária in vitro de peptídeos inibidores da dissulfeto isomerase protéica - etapa 2." Universidade Federal do Maranhão, 2016. http://tedebc.ufma.br:8080/jspui/handle/tede/1632.
Повний текст джерелаMade available in DSpace on 2017-06-14T18:35:57Z (GMT). No. of bitstreams: 1 HiranReisSousa.pdf: 2489901 bytes, checksum: 8a82807f0600af87559439a496bd0d2a (MD5) Previous issue date: 2016-12-06
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ)
Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão (FAPEMA)
Recent researches have emphasized the importance of redox mechanisms for platelet function modulation. The platelet surface contains a large variety of integrin receptors and other molecules presenting functional thiol groups in their structures, which are potential targets for redox regulation. Among these various thiol-containing proteins, integrin αIIbβ3 stands out for being the convergence path of platelet activation induced by various agonists. Activation of αIIbβ3 integrin is catalyzed by protein disulfide isomerase (PDI) through an essential conformational change leading to the exposure of fibrinogen-binding site. Thus, PDI has been shown to be an important target for the development of antiplatelet drugs. In recent years, many studies have described substances from plan (DE A. PAES et al., 2011), as well as synthetics that are capable of inhibiting PDI. In a previous study of our research group has shown that the synthetic peptide CxxC, which contains the redox motif of PDI in its original sequence CGHC, inhibited reductase activity of this enzyme, effect not observed with AxxA peptide, whose cysteines were replaced with alanine and Scr peptide, which contains the same aminoacids from CxxC peptide, but under random sequence. It has been also demonstrated that CxxC peptide was the only to reduce by 30% ADP-induced aggregation (5μM) in platelet rich plasma, an effect apparently mediated by the association of CxxC and PDI at platelet surface. Thus, in this work, we further assessed the effects of CxxC and its control peptides on platelet aggregation. Washed human platelets were incubated with CxxC peptide at concentrations of 3, 6 and 10 μM, resulting in a dose-dependent inhibition of maximum aggregation activated by thrombin (0.02 U/mL) at 25, 60 and 74%, respectively with IC50 of 6.13 ± 1.09 μM. The presence of control peptides did not produce any inhibitory effect. CxxC peptide also reduced the activation of αIIbβ3 integrin at platelet surface, but did not affect the expression of the markers CD 62-P and CD 63. Control peptides did not alter the expression of these markers. Analysis by mass spectrometry of the interaction of recombinant human PDI with the peptide showed that only CxxC peptide associated with the redox Cys400 of a’ motif of PDI, which has been considered essential for platelet aggregation. Together, these results demonstrate that CxxC peptide reduces platelet aggregation by association with PDI and can be further used as a model for the development of new antithrombotic drugs.
Investigações recentes têm enfatizado a importância de mecanismos redox na modulação da função plaquetária. A superfície da plaqueta contém grande variedade de integrinas e outras moléculas receptoras que possuem tióis funcionais em sua estrutura, os quais são alvos potenciais de regulação redox. Dentre estas várias proteínas tiólicas, a integrina αIIbβ3 destaca-se por ser a via de convergência da ativação plaquetária induzida por diversos agonistas. A ativação da integrina αIIbβ3 é catalisada pela proteína dissulfeto isomerase (PDI), essencial à mudança de conformação que leva à exposição do sitio de ligação ao fibrinogênio. Sendo assim, a PDI tem se mostrado como um alvo importante para o desenvolvimento de fármacos reguladores da agregação plaquetária. Nos últimos anos, diversos estudos têm descrito substâncias de origem vegetal, animal e sintéticas que são capazes de inibir a PDI. Em trabalho do nosso grupo de pesquisa (DE A. PAES et al., 2011), demonstrou que o peptídeo sintético CxxC, o qual contém o motivo redox da PDI na sua sequência original CGHC, inibiu a atividade redutase desta enzima; efeito não observado com os peptídeos AxxA, que possui as cisteínas substituídas por alanina e Scr, peptídeo controle contendo os mesmos aminoácidos do peptídeo CxxC, porém com sequência aleatória sem formação de ditiol. Demonstrou-se, também, que apenas o peptídeo CxxC reduziu em 30% a agregação induzida por ADP (5M) em plasma rico em plaquetas, efeito aparentemente mediado pela associação do CxxC com a PDI na superfície plaquetária. Sendo assim, neste trabalho continuamos a avaliação dos efeitos do peptídeo CxxC e seus controles sobre a agregação plaquetária. Para tanto, incubamos lavado de plaquetas humanas com o peptídeo CxxC nas concentrações de 3, 6 e 10 μM, resultando em inibição concentração-dependente da agregação ativada por trombina (0,02 U/mL) em 25, 60 e 74 %, respectivamente, com IC50 de 6,13 ± 1,09 μM. A presença dos peptídeos controle não produziu quaisquer efeitos inibitórios. O peptídeo CxxC reduziu a ativação da integrina αIIbβ3 na superfície da plaqueta, porém não impactou a expressão dos antígenos CD 62-P e CD 63. Os peptídeos controle não alteraram a expressão desses marcadores. A análise por espectrometria de massas da interação da PDI recombinante humana com os peptídeos, mostrou que apenas o peptídeo CxxC associa-se com a Cys400 do motivo redox a’ da hPDI, o qual tem sido considerado fundamental para a agregação plaquetária. Em conjunto, estes resultados demonstram que o peptídeo CxxC reduz a agregação plaquetária via associação com a PDI, podendo ser empregado como modelo para o desenvolvimento de fármacos novos antitrombogênicos.
Hammad, Mohammad. "In vitro properties of novel root canal filling materials." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502267.
Повний текст джерелаMould, A. P. "The aggregation properties of type I procollagen in vitro." Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377670.
Повний текст джерелаZhang, Qing. "Role of Polymer Physicochemical Properties on in vitro Mucoadhesion." Scholarly Commons, 2020. https://scholarlycommons.pacific.edu/uop_etds/3698.
Повний текст джерелаКниги з теми "In vitro antithrombotic properties"
Pickering, Anthony Edward. Integrative properties of rat sympathetic preganglionic neurones in vitro. Birmingham: University of Birmingham, 1993.
Знайти повний текст джерелаReska, Anna. Elektrophysiologische Charakterisierung neuronaler Netzwerke von Insekten in vitro. Jülich: Forschungszentrum Jülich, 2006.
Знайти повний текст джерелаRandall, Robert Lawrence Merrill. Sequential dependence of in vitro freeze-drying and irradiation on the biomechanical properties of rat bone. [s.l: s.n.], 1992.
Знайти повний текст джерелаWells, Jeffrey Donald. The processing and in vitro degradation properties of gravity sintered calcium polyphosphate powders. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.
Знайти повний текст джерелаLnenicek-Allen, Mirna. Studies of the DNA binding and bending properties of HMG boxes using in vitro mutagenesis. Portsmouth: University of Portsmouth, School of Biological Sciences, 1998.
Знайти повний текст джерелаLarochelle, Elaine. Comparative "in vitro" study of chemical properties of cavity liners: PH level, calcium and fluoride release measurements. [Toronto: Faculty of Dentistry, University of Toronto], 1989.
Знайти повний текст джерелаCelotti, Carlo Emilio. The effects of prior heat shock on in vitro muscle contractile properties at 20°C amd 42°C. Ottawa: National Library of Canada, 2003.
Знайти повний текст джерелаLiu, Siyu. Antithrombotic/antiplatelet properties and mechanism of action of tetramethylpyrazine, including structure-activity relationship studies. 1991.
Знайти повний текст джерелаHartley, Richard William. The development of an in-vivo method for assessing the antithrombotic properties of pharmaceutical compounds. 1989.
Знайти повний текст джерелаOmelon, Sidney Jennifer. Material properties, and in vitro and in vivo degradation of calcium polyphosphate. 2006.
Знайти повний текст джерелаЧастини книг з теми "In vitro antithrombotic properties"
Caen, J. P., Y. Legrand, A. Karniguian, D. Leger, C. Soria, J. Soria, and J. Fareed. "In Vitro and in Vivo Antithrombotic Effect of a Collagen-Derived Octapeptide." In Cardiovascular Disease, 277–81. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5296-9_32.
Повний текст джерелаOsol, George. "Myogenic Properties of Blood Vessels In Vitro." In The Resistance Vasculature, 143–57. Totowa, NJ: Humana Press, 1991. http://dx.doi.org/10.1007/978-1-4612-0403-9_9.
Повний текст джерелаTraub, Roger D., and Richard Miles. "Some Collective Phenomena in the Hippocampus in Vitro." In Self-Organization, Emerging Properties, and Learning, 97–112. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3778-6_7.
Повний текст джерелаYamagami, Masahito, Shohei Sawada, Toshiyuki Tamagaki, Kyoichiro Kobayashi, Kazuharu Kato, Katsumi Yamamoto, Kaoru Shirai, et al. "Effects of Intracellular pH on the Antithrombotic Properties of Human Vascular Endothelial Cells." In Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets, 175–82. Tokyo: Springer Japan, 1993. http://dx.doi.org/10.1007/978-4-431-68323-0_30.
Повний текст джерелаNaiki, Hironobu, Keiichi Higuchi, Kazuya Nakakuki, and Toshio Takeda. "Kinetic Properties of Amyloid Fibril Polymerization in Vitro." In Amyloid and Amyloidosis 1990, 493–96. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3284-8_122.
Повний текст джерелаGokcekaya, Ozkan, Kyosuke Ueda, Takayuki Narushima, Kouetsu Ogasawara, and Hiroyasu Kanetaka. "In Vitro Properties of Ag-Containing Calcium Phosphates." In Ceramic Engineering and Science Proceedings, 85–93. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119321682.ch10.
Повний текст джерелаMoore, Anna R., Wen-Liang Zhou, Igor Jakovcevski, Nada Zecevic, and Srdjan D. Antic. "Physiological Properties of Human Fetal Cortex In Vitro." In Isolated Central Nervous System Circuits, 125–58. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-020-5_3.
Повний текст джерелаKay, S. A. "In Vitro Protein-DNA Interactions in the Rice Phytochrome Promoter." In Phytochrome Properties and Biological Action, 129–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75130-1_8.
Повний текст джерелаBruch, J., and J. Rosmanith. "Properties of Mixed Mine Dusts and Their Relationship to Pneumoconiosis." In In Vitro Effects of Mineral Dusts, 433–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70630-1_55.
Повний текст джерелаChandy, Thomas, and Chandra P. Sharma. "Urokinase:AT-III:PGE1:Methyl Dopa Complex Immobilized Albumin-Blended Chitosan Membranes — Antithrombotic and Permeability Properties." In Applied Bioactive Polymeric Materials, 297–311. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5610-3_22.
Повний текст джерелаТези доповідей конференцій з теми "In vitro antithrombotic properties"
Rehse, K., U. Lukens, S. Leibring, V. Schein, and A. Kesselhut. "ANTITHROMBOTIC OLIGOAMINES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643439.
Повний текст джерелаCasu, B., L. Marchese, A. Naggi, G. Torri, J. Fareed, A. Racanelli, and J. M. Walenga. "INFLUENCE OF THE SULFATION PATTERN ON CERTAIN BIOLOGICAL PROPERTIES OF GALACTOSAMINOGLYCANS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643251.
Повний текст джерелаDhall, D. P., A. G. Shah, and C. H. Nair. "ANTITHROMBOTIC PROPHYLAXIS THROUGH MODIFICATION OF FIBRIN NETWORK STRUCTURE:A NEW APPROACH." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643313.
Повний текст джерелаOfosu, F. A., G. J. Modi, M. A. Blajchman, M. R. Buchanan, and E. A. Johnson. "INCREASED SULFATION IMPROVES THE ABILITY OF VESSEL WALL GLYCOSA-MINOGLYCANS TO REGULATE THROMBIN ACTIVITY AND PROTHROMBIN ACTIVATION IN PLASMA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643252.
Повний текст джерелаde Agostini, A., J. Marcum, and R. Rosenberg. "THE BINDING OF ANTITHROMBIN TO CAPILLARY ENDOTHELIAL CELLS GROWN IN VITRO." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643343.
Повний текст джерелаMerton, R. E., T. W. Barrowcliffe, and D. P. Thomas. "A COMPARISON OF DERMATAN SULPHATE AND HEPARIN AS ANTITHROMBOTIC DRUGS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642933.
Повний текст джерелаHoppensteadt, D., A. Kumar, J. Fareed, and J. Mardigian. "STUDIES ON THE ANTICOAGULANT AND ANTITHROMBOTIC ACTIONS OF DERMATANS AND THEIR SULFATED DERIVATIVES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643241.
Повний текст джерелаCornelli, U., J. M. Welena, J. Fareed, X. Huan, and D. Hoppensteadt. "ANTITHROMBOTIC ACTIONS OF A SULFOMUCOPOLYSACCHARIDE MIXTURE (ATERIOD) IN ANIMAL MODELS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644160.
Повний текст джерелаWitt, W., B. Baldus, and P. Donner. "ANTITHROMBOTIC EFFECTS OF TISSUE-TYPE PLASMINOGEN ACTIVATOR AT PHYSIOLOGICAL BLOOD LEVELS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643575.
Повний текст джерелаMüller, T. H., K. Rühr, H. H. Callisen, and W. G. Eisert. "MODULATION OF ANTITHROMBOTIC EFFECTS OF CULTURED HUMAN ENDOTHELIAL CELLS BY INHIBITORS OF CYCLOOXIGENASE OR PHOSPHODIESTERASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643364.
Повний текст джерелаЗвіти організацій з теми "In vitro antithrombotic properties"
Davidson, Irit, Hsing-Jien Kung, and Richard L. Witter. Molecular Interactions between Herpes and Retroviruses in Dually Infected Chickens and Turkeys. United States Department of Agriculture, January 2002. http://dx.doi.org/10.32747/2002.7575275.bard.
Повний текст джерелаSchuster, Gadi, and David Stern. Integrated Studies of Chloroplast Ribonucleases. United States Department of Agriculture, September 2011. http://dx.doi.org/10.32747/2011.7697125.bard.
Повний текст джерелаGalili, Gad, and Alan Bennett. Role of Molecular Chaperone in Wheat Storage Protein Assembly. United States Department of Agriculture, April 1995. http://dx.doi.org/10.32747/1995.7604926.bard.
Повний текст джерелаEvans, Donald L., Avigdor Eldar, Liliana Jaso-Friedmann, and Herve Bercovier. Streptococcus Iniae Infection in Trout and Tilapia: Host-Pathogen Interactions, the Immune Response Towards the Pathogen and Vaccine Formulation. United States Department of Agriculture, February 2005. http://dx.doi.org/10.32747/2005.7586538.bard.
Повний текст джерелаShoseyov, Oded, Steven A. Weinbaum, Raphael Goren, and Abhaya M. Dandekar. Biological Thinning of Fruit Set by RNAase in Deciduous Fruit Trees. United States Department of Agriculture, August 1993. http://dx.doi.org/10.32747/1993.7568110.bard.
Повний текст джерелаSessa, Guido, and Gregory Martin. role of FLS3 and BSK830 in pattern-triggered immunity in tomato. United States Department of Agriculture, January 2016. http://dx.doi.org/10.32747/2016.7604270.bard.
Повний текст джерелаLevisohn, Sharon, Maricarmen Garcia, David Yogev, and Stanley Kleven. Targeted Molecular Typing of Pathogenic Avian Mycoplasmas. United States Department of Agriculture, January 2006. http://dx.doi.org/10.32747/2006.7695853.bard.
Повний текст джерелаSessa, Guido, and Gregory Martin. A functional genomics approach to dissect resistance of tomato to bacterial spot disease. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695876.bard.
Повний текст джерелаTzfira, Tzvi, Michael Elbaum, and Sharon Wolf. DNA transfer by Agrobacterium: a cooperative interaction of ssDNA, virulence proteins, and plant host factors. United States Department of Agriculture, December 2005. http://dx.doi.org/10.32747/2005.7695881.bard.
Повний текст джерелаLichter, Amnon, David Obenland, Nirit Bernstein, Jennifer Hashim, and Joseph Smilanick. The role of potassium in quality of grapes after harvest. United States Department of Agriculture, October 2015. http://dx.doi.org/10.32747/2015.7597914.bard.
Повний текст джерела