Готові списки джерел за темами / Implication du patient

Добірка наукової літератури з теми "Implication du patient"

Автор: Grafiati

Опубліковано: 4 травня 2024

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Статті в журналах з теми "Implication du patient"

Bertoncini, Fabio, Dino Stefano Di Massimo, and Claudia Gatta. "Sepsis: implication for nursing." Italian Journal of Medicine 10, no. 4 (December 15, 2016): 360. http://dx.doi.org/10.4081/itjm.2016.801.

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Sepsis is a serious health problem that is off worldwide interest; it is associated with a high mortality rate despite continuing improvements in infection management and the awareness of population is still poor despite its importance. Direct interventions to achieve the goal of clinician, like reduction of mortality, pass through the resuscitation and antibiotics but their effectiveness depends on the early recognition of symptoms and therefore the septic state. The nursing role is crucial both for the early recognition of the disease state, as well as to treat the patient with professionalism and promptness and to provide appropriate assistance to the kind of complexity that creates this pathological state: to achieve these aims, recommendations and bundles were developed to guide clinical nurses in septic patients’ care.

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S, Rawat. "Implication of Ayurveda in the Management of Apasmara (Epilepsy) – Case Study." Journal of Natural & Ayurvedic Medicine 7, no. 1 (January 4, 2023): 1–5. http://dx.doi.org/10.23880/jonam-16000386.

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Epilepsy affects 1% of the world’s population a most common serious disorder of the brain, greatly impacting on the quality of life of affected individuals. In Ayurveda, the similar presentation is named as Apasmara has been explained with its aetiology, diagnosis and management. Imbalance in the three Doshas Vata, Pitta, Kapha singly or all of them together can cause Apasmara. Those aggravated Doshas get accumulated in Hridya and produce the features based upon Doshika predominance which cause illusion of the mind and visual hallucination and seizures (tonic spasms and clonic jerks) often it is presented with outwarding tongue, deviation of eyes, dribbling of saliva with froth, tonic and clonic movements of limbs. Even though medical world claims of the advancements in the management of Apasmara drugs don’t work as they expect. The present Anti-epileptic drugs medication has so many drawbacks like adverse drug interaction and teratogenicity, cognitive impairment to an extent is also seen in some patients with epilepsy. An 18-year male patient arrived to the OPD and complained of seizure attack from last 6 years. The patient sought out ayurvedic treatment because he had tried numerous allopathic treatments but did not get significant result. With the Ayurvedic treatment, remarkable changes in the symptoms of Epilepsy were seen.

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Xi, Yiyun, Youjia Yin, and Jinquan Zhang. "Delay Discounting Clinical Implication for BED Treatment." Journal of Education, Humanities and Social Sciences 8 (February 7, 2023): 2531–36. http://dx.doi.org/10.54097/ehss.v8i.5026.

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Binge Eating Disorder (BED), a common eating disorder appearing in people in their late 20s, shows a symptom of consuming an unusual amount of food in a short amount of time. BED is usually defined as repeated episodes of binge eating accompanied by feelings of loss of control and distress, but unlike bulimia nervosa (BN), BED does not involve inappropriate compensatory behaviors to maintain weight, such as excessive dieting or exercise. Research has already begun to look at the neural mechanisms of overeating. This paper focuses on the finding of a new treatment for BED patient without the usage of medication. The proposed methods are using stimuli and therapy to regulate the focus of the patients’ eating behavior, self-evaluation, and social behaviors. The results obtained from the research included the effect of delay discounting of each method of treatment on the patient. The findings indicated that reducing delay discounting has clinical implications for the treatment of BED.

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Bansode-Gokhe, Seema, Rakesh Waghmare, and Ratnerdra Ratnendra. "Diabetes mellitus: Implication in rural area of Thane district, India." Journal of Social Health and Diabetes 03, no. 01 (June 2015): 039–42. http://dx.doi.org/10.4103/2321-0656.140887.

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Abstract Context: Diabetes mellitus along with its complications contribute a significant amount of burden on the society. Lack of awareness has resulted in an increased number of diabetics over the years. Aims: To study the sociodemographic status, complication profile and perception of diabetic patients regarding their illness. Settings and Design: Cross sectional center based study done on 110 type 2 diabetic patients over a period of 5 months at rural health training center. Materials and Methods: Universal sampling technique was used. All old and newly diagnosed diabetic patients were interviewed by Face to Face interview method. Statistical Analysis: Descriptive statistics for sociodemographic factors and morbidity; cross tabulation by using test of significance to find association between different variables were used. Results: 50% patients were illiterate, 91.82% were married and 44.5% were farmers. The perception of self-health was reported GOOD on Stanford patient education research center questionnaire scale in 62.7% patients; these responses were significantly associated with males. 61.81% patient had symptoms of coronary heart disease (CHD). 87.3%, 59.1%, and 58.2% patient had symptoms of neuropathy, nephropathy and retinopathy respectively. Out of 61 patients who were aware of complications only 1/10th were aware with the fact that diabetes can affect eye and heart. Conclusions: Almost half patients were unaware that disease is associated with complications and in remaining halves awareness was negligible for neuropathy and nephropathy. In contrast around 2/3rd patients had symptoms of CHD, nephropathy and retinopathy.

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Miligy, Dawlat A. "Laboratory errors and patient safety." International Journal of Health Care Quality Assurance 28, no. 1 (February 9, 2015): 2–10. http://dx.doi.org/10.1108/ijhcqa-10-2008-0098.

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Purpose – Laboratory data are extensively used in medical practice; consequently, laboratory errors have a tremendous impact on patient safety. Therefore, programs designed to identify and reduce laboratory errors, as well as, setting specific strategies are required to minimize these errors and improve patient safety. The purpose of this paper is to identify part of the commonly encountered laboratory errors throughout our practice in laboratory work, their hazards on patient health care and some measures and recommendations to minimize or to eliminate these errors. Design/methodology/approach – Recording the encountered laboratory errors during May 2008 and their statistical evaluation (using simple percent distribution) have been done in the department of laboratory of one of the private hospitals in Egypt. Errors have been classified according to the laboratory phases and according to their implication on patient health. Findings – Data obtained out of 1,600 testing procedure revealed that the total number of encountered errors is 14 tests (0.87 percent of total testing procedures). Most of the encountered errors lay in the pre- and post-analytic phases of testing cycle (representing 35.7 and 50 percent, respectively, of total errors). While the number of test errors encountered in the analytic phase represented only 14.3 percent of total errors. About 85.7 percent of total errors were of non-significant implication on patients health being detected before test reports have been submitted to the patients. On the other hand, the number of test errors that have been already submitted to patients and reach the physician represented 14.3 percent of total errors. Only 7.1 percent of the errors could have an impact on patient diagnosis. Practical implications – The findings of this study were concomitant with those published from the USA and other countries. This proves that laboratory problems are universal and need general standardization and bench marking measures. Originality/value – Original being the first data published from Arabic countries that evaluated the encountered laboratory errors and launch the great need for universal standardization and bench marking measures to control the laboratory work.

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Freixas Sala, Núria, Olga Monistrol Ruano, Jordi Espuñes Vendrell, Montserrat Sallés Creus, Mónica Gallardo González, Carme Ramón Cantón, María José Bueno Domínguez, Montserrat Llinas Vidal, and María Antonia Campo Osaba. "Patient safety and nursing implication: Survey in Catalan hospitals." Enfermería Clínica (English Edition) 27, no. 2 (March 2017): 94–100. http://dx.doi.org/10.1016/j.enfcle.2016.03.001.

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Josan, Lucian, Alina Ormenisan, Elina Teodorescu, Delia Daragiu, and Mariana Pacurar. "Patient’s interest towards interconnection and social implication with trainer doctor model." Romanian Journal of Stomatology 68, no. 4 (December 31, 2022): 169–77. http://dx.doi.org/10.37897/rjs.2022.4.3.

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OED and the dictionary of the world defines a "doctor" 700 years ago and today as a "teacher". The root word for the word doctor derives from Latin "docere", which means "to teach". The doctor contributes to educating patients about a number of medical conditions (the patient is experiencing a number of diseases). In essence, the doctor has the role as a teacher. Doctor-patient interaction works on relational models. The physician-trainer paradigm is required to be introduced to improve patient status. The physician-trainer model is a participatory model that results in achieving the patient's well-being and improving his/her health; the physician uses his or her capacity as a trainer, that is, he has the ability to form and instill adequate conduct for each patient. In this paper, besides highlighting the appetence for the relationship between the trainer and the patient, we tried to quantify the patient's acceptance of the treatment with/without continuous monitoring of the disease (chronic diseases), the degree of reasonableness in accepting the therapeutic behavior, and lastly how the individual feels the change of his status in the patient. The study was conducted on a total of 217 subjects (125 female subjects and 92 male subjects). The applied questionnaire contained 18 questions, structured to help us confirm or not the study's objectives. The results obtained will show us the level of appetite for the trainer-patient relationship.

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Bansal, Rimpi, Puneet Kaur, Jatin Sarin, Anureet Kaur, and Akshita Sarin. "Incidence and Prognostic Implication of Bone Marrow Involvement in Hodgkin’s Lymphoma." Annals of Pathology and Laboratory Medicine 8, no. 11 (December 2, 2021): A239–242. http://dx.doi.org/10.21276/apalm.3010.

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Introduction- : Conducting Bone marrow examination in a Hodgkin's Lymphoma (HL) patient at the time of diagnosis is done routinely to determine the stage of the disease. The aim of this study was to analyze the incidence and prognosis of bone marrow involvement in patients with Hodgkins lymphoma, retrospectively. Materials and Patients: Ten patients of Hodgkins lymphoma were incorporated in the current study. Bone marrow aspiration and biopsy was done in all ten cases as part of staging procedure. Results: Three patients showed involvement of bone marrow by Hodgkin’s lymphoma and both the patients had clinically poor outcome. Discussion and Conclusion: Bone marrow examination is important in stage II and III of Hodgkin”s lymphoma because positive result will upstage the disease. Also, bone marrow involvement indicates an aggressive disease and poor prognosis for the patient.

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Njomboro, Progress, and Shoumitro Deb. "Poor Dissociation of Patient-Evaluated Apathy and Depressive Symptoms." Current Gerontology and Geriatrics Research 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/846075.

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Apathy has traditionally been conceptualised as part of depression. The appropriateness of this conceptualisation has now been questioned, with the realization that apathy constitutes a distinct neuropsychiatric condition, with separate rehabilitation and patient-care implications to depression. Research on the relationship between apathy and depression has, however, produced mixed results. One reason for this inconsistency may lie behind who does the apathy evaluation. In this study we investigated whether the relationship between apathy and depression would differ when apathy was evaluated by the patients or an informant. A total of 49 brain damaged patients were assessed on self- and informant-rated Apathy Evaluation Scales. The relationship between the apathy scores and depressive symptoms was then investigated. Patient-rated, and not informant-rated apathy significantly correlated with depression. We discuss the implication of these results on the relationship between the two neuropsychiatric conditions and also in relation to the utility of patient self-evaluations in apathy.

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Damayanti, Triya, and Sri Pudyastuti. "Asthma in Pregnancy: Mechanism and Clinical Implication." Jurnal Respirologi Indonesia 40, no. 4 (October 23, 2020): 251–61. http://dx.doi.org/10.36497/jri.v40i4.125.

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Asthma in pregnancy can influence clinical status of an asthma patient. Study showed that one third of asthma patients were worsening, one third stable and one third improving. During pregnancy, lung function, ventilation pattern and gas diffusion are influenced by biochemistry (hormonal) and mechanic. Mechanism in pregnancy with asthma including hypoxia, inflammation, corticosteroids therapy, history of exacerbation, smoking mother and changes in placenta function. Hormonal status during pregnancy is different with non-pregnancy woman which hormonal level changes through the pregnancy time. Those changes can influence lung function in pregnancy. Treatment of asthma in pregnancy is giving optimal asthma therapy, therefore it can improve asthma control, also the quality of life of a mother and her fetus during pregnancy.

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Більше джерел

Дисертації з теми "Implication du patient"

Welwel, Ghada. "Multi-disciplinary approach to obesity management and bariatric surgery." Electronic Thesis or Diss., Université Paris Cité, 2019. http://www.theses.fr/2019UNIP5152.

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L'étude vise les raisons, les connaissances et les attentes des personnes subissant une chirurgie bariatrique au Moyen-Orient et en Jordanie. Une étude rétrospective a été conçue et menée au Centre de la prise en charge de l'obésité Mohammad Al-Zitawi entre 2015 et 2017. 154 patients (hommes: 45; femmes: 109) - ayant une masse corporelle supérieure à 40 kg / m2 et âgés de 20 à 60 ans- ont participé à l'étude. Ils ont été choisis au hasard. Ils représentaient 10% des patients adultes au centre de l'obésité de la période de l'étude. Âgés de 20 à 60 ans, les participants a l'étude ont été orientées vers l'unité bariatrique du Centre Al-Zitawi. Le comité d'éthique du centre a approuve le protocole de l'étude. Tous les aspects éthiques ont été respectes au cours de l'enquête. La bienfaisance (bien faire), la non-malfaisance (ne justifie pas les patients), la fidélité, la confiance, le respect, le traitement impartial, le respect culturel, le droit à la justice, le respect de la confidentialité, le droit à la prise de décision et la décision volontaire ont été prises en compte. Il s'agit d'une étude rétrospective. Deux questionnaires ont été conçus: un pour les patients et l'autre pour les professionnels impliqués de la prise en charge de l'obésité. Les entretiens et le consentement des patients ont été obtenus par téléphone (chez eux, loin du centre). Les questions de l'étude a opte l'approche des méthodes mixtes pour améliorer la qualité des données collectées.Il s'agit d'une méthodologie de recherche croissante. Elle fait progresser le mélange systématique de données qualitatives et quantitatives au sein d'une même enquête ou d'un programme de recherche constant. Elle permet une utilisation complète et synergique des données. Elle donne toutefois la parole aux participants et les résultats sont basés sur l'expérience des participants. Elle laisse une place à l'équipe multidisciplinaire par la recherche en favorisant le contact des chercheurs en méthodes quantitatives, qualitatives et mixtes (Creswell et al., 2011). Les résultats montrent que les patients du Moyen-Orient n'avaient pas de connaissances et de compréhension à propos de la chirurgie bariatrique Les études de Taube-Schiff et al. (2016) et Guler et al. (2018), indiquent que les patients obèses, même dans les pays développés, ont peu de connaissance à propos des chirurgies bariatriques, Une étude récente saoudienne d'Altaf & Abbas (2019) révèle que la sensibilisation du public à l'obésité et à la chirurgie bariatrique est très limitée. Notre étude révèle une insuffisance évidente a propos de la prise de conscience et la connaissance de la chirurgie bariatrique chez les patients participants du Moyen-Orient. Différentes plates-formes sont essentielles pour mieux faire connaître la chirurgie bariatrique et ses avantages, ses facteurs de risque et ses complications associés. La revue des pratiques des chirurgiens et des éducateurs sanitaires est évidente. La plupart des patients de l'étude n'ont pas apprécié le service rendu et les bénéfices de la chirurgie. La sensibilisation du public, les services de gestion du poids, du changement de comportement et de la gestion de soi sont essentiels pour améliorer le service rendu à long terme de la chirurgie bariatrique et répondre aux attentes des patients
The study aimed to understand the reasons, knowledge and expectations of people undergoing bariatric surgery in Middle East and Jordan. A retrospective study is designed and was conducted in the Mohammad Al-Zitawi Obesity Management Centre between the years 2015 and 2017. A total of 154 participants (males: 45; females: 109) who had body mass greater than 40kg/m2 and aged between 20-60 years took part in the study. The study participants were randomly selected and enrolled participants were 10% of the patients who attended obesity management centre in that particular year. All study patients were above 20 years of age and had been referred to the bariatric unit at Al- Zitawi Obesity Management Centre. A total of 154 patients (males: 45; females: 109) who had body mass greater than 40kg/m2 and aged between 20-60 years took part in the study. Ethical approval for the study was taken from hospital ethical committee. At the time of filling up of questionnaire forms all ethical aspects such as beneficence (doing good), non malfeasance (not justifying patients), fidelity, trust, respect, unbiased treatment, cultural respect, right to justice, maintenance of confidentiality, right to decision making and voluntary decision were taken into consideration. The methodology involves two tier questionnaires; one for patients and the other one for the professionals involved in obesity management. Since, it is a retrospective study and participants are not in the city. Questionnaire forms and patients consent was obtained on phone from the participants. Filling up of questionnaire form was on phone. Questions were explained to participants on phone in English and Islamic language and consent was obtained. In the present study, we used mixed method approach to improve the quality of our research study. Mixed method approach refers to growing methodology of research that progress the systematic mixing of both qualitative and quantitative datum within a single investigation or constant programme of investigation. Mixed up approach allows complete and synergic use of data. Furthermore, this method gives voice to study participants and make sure that enrolled participants are part of study and results are base on participant's experience. This kind of approach provides space to multidisciplinary team by research by promoting the contact of quantitative, qualitative, and mixed methods scholars (Creswell et al., 2011). The results of our study showed that patients in the Middle East do not have much knowledge and understanding about the bariatric surgery and this finding is in consistent with the studies of Taube-Schiff et al. (2016) and Guler et al. (2018) indicating that usually obese patients have limited knowledge about bariatric surgeries even in the developed countries. Moreover, a recent research documented by Altaf & Abbas (2019) in Saudi Arab documents that the public awareness about obesity and bariatric surgery is very limited. Our study shows an obvious gap in awareness and knowledge about bariatric surgery among the studied participants from the Middle East. There is a need of using different platforms for spreading accurate awareness about Bariatric surgery and its associated benefits, risk factors and associated complications. Public awareness should be created by surgeons and health educators and they should act accordingly to develop better knowledge and awareness among general public. Most of patients in our study fail to meet their expectations from surgery as benefits of treatment. Our study also throws light on the significance of weight management services, behavioural change and self management in modifying patient's expectations of having long term benefits of bariatric surgery

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Roche, Stéphanie. "Conseil au patient en fin d'hospitalisation : une implication du pharmacien hospitalier dans la prévention de l'iatrogénie médicamenteuse." Reims, 2008. http://www.theses.fr/2008REIMP054.

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Harry, Isabelle. "Analyse des échanges écrits entre patients adultes et parents d'enfants, diabétiques de type 1, sur les forums d'Internet : implication pour l'éducation thérapeutique du patient." Phd thesis, Université Paris-Nord - Paris XIII, 2011. http://tel.archives-ouvertes.fr/tel-00695514.

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L'éducation thérapeutique permet aux patients de développer des compétences d'auto-soins et d'adaptation dans la gestion de la maladie chronique. Notre thèse a pour but de comprendre leur nature, à partir des situations de vie quotidienne dont discutent les adultes diabétiques de type 1 et les parents d'enfants diabétiques de type 1, sur les forums asynchrones d'Internet. Nous avons analysé 3756 messages écrits durant trois années, sur deux forums de discussion (314 patients diabétiques sont inclus dans l'étude) et réalisé des entretiens auprès de patients volontaires et usagers de ces forums. Nous avons utilisé les recommandations professionnelles publiées par la HAS et l'INPES (2007), pour relier nos résultats avec leur référentiel de compétences du patient chronique et pour rapporter à des objectifs pédagogiques les thématiques abordées par les discussions sur les forums. Ainsi, nos résultats mettent en évidence la capacité des patients à renforcer, via les forums d'internet, des compétences d'auto-soins liées à leur sécurité. La nature des compétences d'adaptation et d'auto-soins, indiquée par nos résultats, souligne le rapport que les patients entretiennent avec la maladie et le traitement. Les perspectives de cette thèse sont donc discutées. Dans le but d'associer les patients à la démarche en éducation thérapeutique, comme le précisent la législation actuelle et les recommandations professionnelles, la possibilité de poursuivre la recherche avec les exemples d'autres pathologies chroniques s'avère une voie pertinente. Mieux comprendre les situations de vie et la nature des compétences révélées par les échanges sur les forums d'Internet permettrait, en respectant les règles éthiques, de contribuer à l'élaboration des programmes d'éducation thérapeutique adaptés aux besoins réels des patients porteurs de maladie chronique. En outre, notre thèse permet de comprendre la nature des situations d'éducation informelle liées à la vie avec un diabète de type1 : nous en discutons l'intérêt pour l'éducation formelle proposée par les soignants éducateurs.

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Harry, Isabelle. "Analyse des échanges écrits entre patients adultes et parents d’enfants, diabétiques de type 1, sur les forums d’internet : implication pour l'éducation thérapeutique du patient." Paris 13, 2011. http://www.theses.fr/2011PA132020.

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L’éducation thérapeutique permet aux patients de développer des compétences d’auto-soins et d’adaptation dans la gestion de la maladie chronique. Notre thèse a pour but de comprendre leur nature, à partir des situations de vie quotidienne dont discutent les adultes diabétiques de type 1 et les parents d’enfants diabétiques de type 1, sur les forums asynchrones d’Internet. Nous avons analysé 3756 messages écrits durant trois années, sur deux forums de discussion (314 patients diabétiques sont inclus dans l’étude) et réalisé des entretiens auprès de patients volontaires et usagers de ces forums. Nous avons utilisé les recommandations professionnelles publiées par la HAS et l’INPES (2007), pour relier nos résultats avec leur référentiel de compétences du patient chronique et pour rapporter à des objectifs pédagogiques les thématiques abordées par les discussions sur les forums. Ainsi, nos résultats mettent en évidence la capacité des patients à renforcer, via les forums d’internet, des compétences d’auto-soins liées à leur sécurité. La nature des compétences d’adaptation et d’auto-soins, indiquée par nos résultats, souligne le rapport que les patients entretiennent avec la maladie et le traitement. Les perspectives de cette thèse sont donc discutées. Dans le but d’associer les patients à la démarche en éducation thérapeutique, comme le précisent la législation actuelle et les recommandations professionnelles, la possibilité de poursuivre la recherche avec les exemples d’autres pathologies chroniques s’avère une voie pertinente. Mieux comprendre les situations de vie et la nature des compétences révélées par les échanges sur les forums d’Internet permettrait, en respectant les règles éthiques, de contribuer à l’élaboration des programmes d’éducation thérapeutique adaptés aux besoins réels des patients porteurs de maladie chronique. En outre, notre thèse permet de comprendre la nature des situations d’éducation informelle liées à la vie avec un diabète de type1 : nous en discutons l’intérêt pour l’éducation formelle proposée par les soignants éducateurs
Therapeutic education enables patients to develop their self-care and adaptation skills in the management of chronic illness. The aim of our thesis is to understand their nature from every day real-life situations which type 1 diabetics adults and the parents of type 1 diabetics children discuss on asynchronous Internet forums. We analysed 3756 messages written over a three-year period on two discussion forums (314 diabetic patients are included in the study) and we interviewed voluntary patients and users of these forums. We used professional recommendations published by the HAS and the INPES (2007), to link our results to their frame of reference of skills developed by patients suffering from chronic illnesses, and related to educational objectives the topics covered by discussions on forums. Thus, our results bring to light the ability of patients with diabetes to strengthen, via the internet forums, self-care skills in association with their security. The nature of the adaptation and self-care skills indicated by our results emphasizes the relationship that the patients have with the illness and the treatment. The prospects of this thesis are therefore discussed. In order to enable the patients to share in the therapeutic education procedure, as stipulated by current legislation and professional recommendations, the possibility to continue research with examples of other chronic pathologies seems a relevant path to follow. A better understanding of real-life situations and the nature of the skills revealed by exchanges on Internet forums, whilst respecting ethical rules, would permit the elaboration of therapeutic education programmes adapted to the real needs of patients with chronic illness. In addition, our thesis permits an approach to the nature of informal educational situations in relation to everyday life with a type 1 diabetes : we discuss their significance for the elaboration of structured therapeutic education programmes proposed by carers

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Alexandre, François. "Implication du système nerveux central dans la faiblesse musculaire périphérique du patient atteint de broncho-pneumopathie chronique obstructive." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONT4003/document.

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La faiblesse des muscles périphériques, définie par une diminution de la force maximale volontaire en dehors de tout état de fatigue neuromusculaire, est une complication fréquente de la broncho-pneumopathie chronique obstructive (BPCO). La force maximale volontaire dépend à la fois des propriétés musculaires périphériques (i.e. volume et architecture musculaire, qualités contractiles) et de la capacité du système nerveux à activer le muscle maximalement. Dans la BPCO, plusieurs travaux ont souligné l'existence paradoxale d'une perte de force maximale volontaire sans altérations musculaires périphériques et sans qu'un déficit d'activation volontaire n'ait clairement été identifié. Pourtant, les patients atteints de BPCO présentent de nombreuses altérations du système nerveux, compatibles avec une capacité d'activation volontaire altérée.L'objectif de ce travail de thèse était donc de tester l'implication du système nerveux dans la faiblesse musculaire de la BPCO et d'en déterminer les mécanismes sous-jacents. Au cours de nos travaux, nous avons mis en évidence une activité corticale diminuée dans la BPCO lors de contractions maximales et sous-maximales volontaires. Nous avons par ailleurs rapporté une perte d'excitabilité du cortex moteur et un déficit d'activation volontaire spécifique aux patients atteints de faiblesse musculaire. Ces résultats sont en accord avec une implication des altérations cérébrales dans la faiblesse musculaire périphérique de la BPCO. Nous sommes ensuite parvenus à identifier une origine potentielle des altérations cérébrales : les désaturations en O2 au cours du sommeil avec mouvements non-rapides des yeux (NREM). Cette hypothèse a été corroborée par l'observation d'un niveau d'activation volontaire réduit chez les patients désatureurs en sommeil NREM. En revanche, aucune répercussion significative n'a pu être observée sur la force maximale volontaire de ces patients, suggérant l'existence d'un mécanisme compensatoire. In fine, nos résultats constituent une avancée importante dans la compréhension du phénomène de faiblesse musculaire, classiquement attribué à la seule perte de masse musculaire. L'implication du système nerveux central dans la faiblesse musculaire ouvre notamment la voie à de nouvelles modalités de prise en charge par des approches spécifiques, dans l'optique de lutter contre la faiblesse musculaire et ses multiples répercussions négatives dans la vie du patient atteint de BPCO
Peripheral muscle weakness, as defined by a reduced voluntary strength outside any state of neuromuscular fatigue, is a common complication of chronic obstructive pulmonary disease (COPD). Maximal voluntary strength is determined by both peripheral muscle properties (i.e. muscle volume and architecture, contractile quality) and the nervous system's ability to activate the muscle maximally. In COPD, many studies highlighted the paradoxical existence of maximal voluntary strength loss without any peripheral muscle impairment, and without a clearly identified voluntary activation deficit. However, patients with COPD exhibited several nervous system alterations compatible with a reduced maximal voluntary activation capacity. The aim of this thesis was to test the nervous system implication in COPD muscle weakness and to determine the involved mechanisms. As major results, we found a reduced cortical activity in COPD during maximal and sub-maximal voluntary contractions. Furthermore, we reported reduced motor cortex excitability and voluntary activation deficit, specifically in patients with muscle weakness. These results are in accordance with an involvement of cortical alterations in COPD muscle weakness. Then, we indentified a potential origin for cortical alterations: O2 desaturation during non-rapid eye movement (NREM) sleep. This hypothesis has been corroborated by the observation of a reduced voluntary activation in patients with NREM sleep desaturation. However, no significant repercussion could have been observed on maximal voluntary strength in these patients, suggesting a compensatory mechanism.Our results are an important step forward in understanding the COPD muscle weakness that was classically attributed to loss of muscle mass only. The involvement of the central nervous system in COPD muscle weakness also brings about new patient care opportunities via tailored approaches, in order to fight against muscle weakness and its deleterious consequences on a patient's life

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Isambert, Céline. "Implication et rôles du pharmacien dans un centre de substitution par la méthadone situé au sein d'un établissement hospitalier parisien." Paris 5, 1999. http://www.theses.fr/1999PA05P107.

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Linden, Caroline. "Pharmacien : acteur de santé, implication du pharmacien dans la prise en charge des usagers de drogues substituées." Paris 5, 1999. http://www.theses.fr/1999PA05P017.

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Musumari, Patou Masika. "A mixed method study on the correlates of patient adherence to antiretroviral therapy in the Democratic Republic of Congo: implication of food insecurity." Kyoto University, 2014. http://hdl.handle.net/2433/188677.

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Goetz, Laurent. "La formation réticulée mésencéphalique : implication dans le contrôle de la locomotion et les troubles de la marche. Approche électrophysiologique chez le primate et le patient parkinsonien." Phd thesis, Université de Grenoble, 2013. http://tel.archives-ouvertes.fr/tel-00872694.

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La compréhension des mécanismes physiologiques et physiopathologiques du contrôle la locomotion et de ses troubles, constitue un enjeu majeur de la recherche biomédicale, pour améliorer la qualité et l'espérance de vie des patients atteints de la maladie de Parkinson. A partir de données expérimentales, la stimulation cérébrale profonde de la formation réticulée mésencéphalique (FRM), incluant les noyaux pédonculopontins et cunéiformes, a été proposée en 2005 comme nouvelle stratégie thérapeutique pour traiter le freezing de la marche. Cependant, au regard de résultats cliniques très hétérogènes, de nombreuses interrogations se posent concernant les connaissances anatomiques et fonctionnelles de la FRM, marquées notamment par un nombre limité de données expérimentales chez le primate non-humain. Cette étude s'inscrit dans une approche translationnelle associant des données cliniques et pré-cliniques. Dans un premier temps, un modèle de locomotion bipède chez le primate non-humain a été développé puis validé à partir de données cinématiques. Une approche IRM multi-séquences a été développée pour permettre un suivi longitudinal du protocole et la construction d'un atlas du tronc cérébral de Macaca fascicularis. Un mapping électrophysiologique de la FRM a ensuite été réalisé chez deux primates éveillés, qui a permis de mettre en évidence pour la première fois, des activités neuronales qui répondaient à la locomotion, confirmant ainsi l'existence d'une région locomotrice mésencéphalique chez le primate. Après intoxication au MPTP, seule une modification du pattern de décharge des neurones de la FRM a été observée, ainsi que des arguments en faveur d'un dysfonctionnement de l'activité de certains neurones de la FRM durant le blocage du pas. Enfin, des enregistrements électrophysiologiques durant des phases de locomotion puis d'endormissement naturel, suggèrent une double implication de populations neuronales dans le contrôle de la locomotion et du niveau de vigilance. La réalisation d'un nouveau système de coordonnées adapté au tronc cérébral humain a permis de réaliser une étude de corrélations anatomo-cliniques des effets de la stimulation cérébrale profonde du noyau pédonculopontin et de proposer une cible probabiliste pour l'implantation d'électrodes dans la FRM pour traiter le freezing de la marche dans le contexte parkinsonien.

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Lanciotti, Marco. "Information Usefulness To Support Dialogue Management in Healthcare." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/24648/.

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The main objective of the framework we are proposing is to help the physician obtain information about the patient's condition in order to reach the \emph{correct} diagnosis as soon as possible. In our proposal, the number of interactions between the physician and the patient is reduced to a strict minimum on the one hand and, on the other hand, it is made possible to increase the number of questions to be asked if the uncertainty about the diagnosis persists. These advantages are due to the fact that (i) we implement a reasoning component that allows us to predict a symptom from another symptom without explicitly asking the patient, (ii) we consider non-binary values for the weights associated with the symptoms, we introduce a dataset filtering process in order to choose which partition should be used with respect to some particular characteristics of the patient, and, in addition, (iv) it was added new functionality to the framework: the ability to detect further future risks of a patient already knowing his pathology. The experimental results we obtained are very encouraging

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Книги з теми "Implication du patient"

Moeller, Grant Marcia, ed. Nursing implications of laboratory tests. 2nd ed. New York: Wiley, 1988.

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McFarland, Mary Brambilla. Nursing implications of laboratory tests. 3rd ed. Albany, N.Y: Delmar, 1994.

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Ergometry in hypertensive patients: Implications for diagnosis and treatment. Berlin: Springer-Verlag, 1985.

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Sara, Paul, and Hebra Jennifer, eds. The nurse's guide to cardiac rhythm interpretation: Implications for patient care. Philadelphia: W.B. Saunders, 1998.

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K, Andres Nicole, Dobson Allen, and American Nurses' Association, eds. Nursing quality indicators: Definitions and implications. Washington, D.C: American Nurses Pub., 1996.

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Ono, Hiromi. Gender, status, role, and adherence: Implications for social structure on patient adherence to medical recommendations. Santa Monica, CA (1700 Main St., P.O. Box 2138, Santa Monica 90407-2138): RAND, 1992.

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Ono, Hiromi. Gender, status, role, and adherence: Implications for social structure on patient adherence to medical recommendations. Santa Monica, CA: Rand, 1992.

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Jordan, Judith V. Relational development: Therapeutic implications of empathy and shame. Wellesley, Mass: Stone Center, Wellesley College, 1989.

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H, Aiken Linda, Sochalski Julie, and International Conference on Hospital Reform and Outcomes Research (1996 : Bellagio, Italy), eds. Hospital restructuring in North America and Europe: Patient outcomes and workforce implications. Hagerstown, MD: Lippincott-Raven, 1997.

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Mullen, Penelope M. Health and the internal market: Implications of the White Paper. Birmingham: University of Birmingham, Health Services Management Centre, 1989.

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Частини книг з теми "Implication du patient"

Bandman, E. L. "Implication of Ethics and Nursing Research for Patient Advocacy." In Medicolegal Library, 126–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-82468-5_21.

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Imafidon, Elvis. "African Ethno-Ethics and Bioethical Principlism: Implication for the Othered Patient." In Ethnophilosophy and the Search for the Wellspring of African Philosophy, 175–87. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-78897-1_11.

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Mondal, Sudip, Namrata Bhattacharya, Troyee Das, Zhumur Ghosh, and Sunirmal Khatua. "Implication of Statistical Methods on Patient Data: An Approach for Cancer Survivability Prediction." In Intelligent Healthcare, 57–80. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67051-1_4.

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Bozan, Karoly, and David Mooney. "Older Adults Empowerment Through Training and Support and Its Implication on Proactive Self-Monitoring, Patient Engagement, and Connected Health." In Healthcare Delivery in the Information Age, 511–34. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17347-0_25.

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Busch, Rebecca Mendoza Saltiel. "Business Processes and Data Implications." In The Cyber Patient, 161–81. Boca Raton : Taylor & Francis, 2019. | “A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc.”: Productivity Press, 2019. http://dx.doi.org/10.4324/9780429490040-8.

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Clout, Ruth, John Murray, Maria Farrell, Daphna Hutt, and Michelle Kenyon. "Cell Therapy, Nursing Implications and Care." In The European Blood and Marrow Transplantation Textbook for Nurses, 101–22. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23394-4_7.

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AbstractOver recent years cellular therapy has seen substantial progress across Europe, particularly cell-based immunotherapy/ immune effector cells (IECs), with the approval of autologous CD19 CAR-T products for patients with relapsed/refractory B-cell malignancies-diffuse large B cell lymphoma, acute lymphoblastic leukaemia (paediatric, teenage and young adult) and mantle cell lymphoma). Whilst this development has delivered benefit to patients with poor risk disease, there is potential for associated toxicities which require careful patient selection, assessment, monitoring, treatment and follow-up care. Nurses play a crucial role in supporting patients throughout this pathway. This chapter focuses on autologous cell-based immunotherapies (CAR-T) process, infusion, toxicities, management and the patient pathway, whilst also exploring non-cell-based immunotherapies, cell therapy in solid tumours and the role of clinical trials.

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Smith, C. Scott, Winslow G. Gerrish, and William G. Weppner. "Implications for Design." In Interprofessional Education in Patient-Centered Medical Homes, 65–81. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20158-0_6.

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Smith, C. Scott, Winslow G. Gerrish, and William G. Weppner. "Implications for Evaluation." In Interprofessional Education in Patient-Centered Medical Homes, 83–99. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20158-0_7.

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Smith, C. Scott, Winslow G. Gerrish, and William G. Weppner. "Implications for Institutions." In Interprofessional Education in Patient-Centered Medical Homes, 101–14. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20158-0_8.

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Liang, Hailun. "Policy Implications and Discussions." In The Impact of Patient-Centered Care, 109–24. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-3968-5_8.

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Тези доповідей конференцій з теми "Implication du patient"

Vimalachandran, Pasupathy, Hua Wang, Yanchun Zhang, Ben Heyward, and Yueai Zhao. "Preserving patient-centred controls in electronic health record systems: A reliance-based model implication." In 2017 International Conference on Orange Technologies (ICOT). IEEE, 2017. http://dx.doi.org/10.1109/icot.2017.8336084.

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Liu, Wei, Hongping Cheng, and Wenjuan Lin. "Discussion on the Cultural Implication and Social Humanity Function of Medical Terms in Doctor-Patient Communication." In 2020 International Conference on Language, Communication and Culture Studies (ICLCCS 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210313.053.

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Al, R. Rifai, MA Jamil, N. Nüsgen, M. Ibrahim, S. Hazzouri El, J. Oldenburg, and O. El-Maarri. "Intrinsic difference in cellular response between full-length and B-domain deleted FVIII HEK293 secreting cells: implication for gene therapy." In GTH Congress 2023 – 67th Annual Meeting of the Society of Thrombosis and Haemostasis Research – The patient as a benchmark. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0042-1760540.

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Martins, Bruna de Almeida, Fernanda Oliveira Carrijo, Guilherme Brandão Martins, Lívia Barbosa Santos, and Erla Lino Ferreira de Carvalho. "Implication of COVID-19 in Guillain-Barre Syndrome: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.095.

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Introduction: The SARS-CoV-2 virus, responsible for COVID-19, was declared in 2020 as a pandemic by the WHO. Due to the new scientific discoveries, correlations between SARS- CoV-2 and neurological manifestations were established. Among them, the Guillain-Barre Syndrome (GBS) is a concern, since it culminates in patient debility. The study has the relevance of knowing the impacts and complications of COVID 19 associated with GBS. In this context, the study presents the guiding question: What are the complications of Covid 19 with GBS? Objectives: To review the literature, highlighting the relationship between COVID- 19 and neurological complications, mainly GBS. Methodology: The study is a literature review, using the PubMed database. The descriptors “Guillain Barre” and “Covid 19” and “Complications” from the last year were used and 56 articles (free, of the type Books and documents; Clinical trial; Controlled and randomized testing; and Analysis) were selected. Results: The studies have shown the existence of an association between GBS and SARS-CoV-2. GBS associated with Covid-19 resulted in manifestations such as facial weakness, limb paresthesia, pain and weakness in the extremities with areflexia. The onset time of neurological symptoms was 6.5 to 11 days after respiratory or systemic characteristics. The liquor is normocellular, hyperproteinorchy, absence of anti-ganglioside antibodies and no SARS-CoV2 was detected in the sample, showing that there is no direct root infection or viral replication. Conclusion: It is concluded that there are neurological complications associated with COVID- 19, emphasizing the GBS, which highlights the need for measures of initial interventions.

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Wei, Po-Li, Chia-Shiuan Tseng, Chien-Chung Chen, Chien-Jin Chiu, and George Hsiao. "Abstract A33: The implication of patient derived tumor cell (PDTC) tested/screened with novel microtube array membrane (MTAM)-based hollow fiber assay (HFA)." In Abstracts: Patient-Derived Cancer Models: Present and Future Applications from Basic Science to the Clinic; February 11-14, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3265.pdx16-a33.

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Lee, Jae Eun, Yoon Young Choi, Ju Yeon Lim, Su-Jin Shin, Gunho Lee, Eun Young Kim, Taeil Son, et al. "Abstract 1037: Comprehensive molecular profiles of gastric cancer patient derived xenograft (PDX) models and its implication in precision cancer medicine." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1037.

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Song, Changho, Ju-Hyun Kim, and Yong-Man Kim. "2022-RA-806-ESGO Implication of FDG-PET/CT parameters for predicting prognosis of high grade neuroendocrine cervical cancer patient." In ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.62.

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Kudlich, Theodor, Maike Wilk, Tilmann Neun, Elena Hartmann, Dorothee Rogoll, Hardi Luehrs, Andreas Rosenwald, et al. "Abstract 2248: Oncogenic actions of HDGF (hepatoma-derived growth factor) in colorectal cancer: Implication for tumor biology/ patient prognosis and modulation by butyrate." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2248.

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Reis, Gabriel Baêta Branquinho, Hugo Francisco da Fonseca Neto, Alice Jardim Zaccariotti, Daniel Bispo de Sousa, Silvaleide Ataides Assunção, Thiago Martins de Abreu, Fernando Santos de Azevedo, and Lanúscia Morais de Santana. "INVASIVE DUCTAL CARCINOMA IN A PATIENT WITH LI-FRAUMENI SYNDROME: A CASE REPORT." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2105.

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Introduction/Objectives: Breast cancer is one of the most common malignancies among women, with 10% resulting from genetic predisposition. Li-Fraumeni syndrome is an autosomal dominant disease that predisposes to multiple primary tumors and is responsible for less than 0.1% of breast cancers, being considered in early-onset tumors. The aim of this report was to describe a fast evolution of three primary tumors in a young patient with Li-Fraumeni syndrome, including ductal breast carcinoma. Case Report: In 2017, a 27-year-old female patient was diagnosed with malignant cancer of the right breast, Luminal HER KI67 70%, clinical stage IV (liver and lung), underwent first-line cancer treatment, maintaining endocrinotherapy and Double Block, with a positive genetic panel test for TP53 mutation, inferring SLF. In 2018, screening colonoscopy showed colon adenocarcinoma, pT53pN1, treated with total colectomy with ileal pouch, followed by suspension of endocrinotherapy and maintenance of Double Block and adjuvant FOLFOX. At the end of chemotherapy, endocrinotherapy was adopted again. Reassessment tests showed partial response in the liver, but the primary nodules were unchanged. Biopsy after thoracoscopy described lung adenocarcinoma, pT3pN2, submitted to adjuvant with Gemzar and Navelbine, followed by Double Block and interruption of endocrinotherapy. It evolved with the appearance of nodules in the right breast, suggestive of progression of breast disease, under treatment with Xeloda, Herceptin, and Perjeta, showing good clinical response. Discussion: Breast cancer in young people increases the possibility of heredity, thus raising the need for investigations of genetic syndromes. Although rare, the identification of FHL brings an important implication for the genetic counseling. Early diagnosis is the best form of management, enabling the preventive screening and intervention of multiple malignancies. Conclusion: Cases of breast cancer in young women should raise a suspected diagnosis of Li-Fraumeni syndrome, which can change the therapeutic and investigation of other cancers at an early stage.

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Orga-Dumitriu, Dan. "THE SILENT THREAT: LONG-COVID'S CARDIAC CONSEQUENCES AND IMPLICATIONS FOR PATIENTS CARE." In 10th SWS International Scientific Conferences on SOCIAL SCIENCES - ISCSS 2023. SGEM WORLD SCIENCE, 2023. http://dx.doi.org/10.35603/sws.iscss.2023/s13.59.

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The article examines the cardiac consequences of long-COVID and their implications for patient care. Long-COVID refers to persistent symptoms and complications that occur in some patients after apparent recover from COVID-19. One concerning aspect of long-COVID is cardiac involvement. Recent studies have found that some patients with long-COVID may experience cardiac complications, including myocarditis, ventricular dysfunction, cardiac rhythm disturbances, and blood clot formation. These conditions can persist in the long term and have significant implications for cardiac health and patients' quality of life. This article emphasizes the importance of careful evaluation and monitoring of patients with long-COVID regarding cardiovascular health. A multidisciplinary approach is necessary, including functional assessment of the heart, monitoring of cardiac rhythm and inflammation markers, and assessment of thromboembolic risk. The implications for patient care, including managing persistent cardiovascular symptoms and managing cardiovascular risk factors, and implementing a personal rehabilitation plan, are discussed. In conclusion, long-COVID can pose a silent threat to cardiac health, and understanding its consequences and implications for patient care is crucial. Further researches are needed to develop optimal management strategies and effective therapeutic interventions to minimize the long-term impact of cardiac conditions among patients with long-COVID.

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Ben-Jonathan, Nira. Antagonism of Taxol Cytotoxicity by Prolactin: Implication for Patient Resistance to Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, March 2008. http://dx.doi.org/10.21236/ada485480.

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Ben-Johnathan, Nira. Antagonism of Taxol Cytotoxicity by Prolactin: Implication for Patient Resistance to Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, March 2009. http://dx.doi.org/10.21236/ada502600.

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Dudley, Lilian D., and Tomás Pantoja. Do educational, organisational or financial interventions improve referrals from primary care to secondary care? SUPPORT, 2016. http://dx.doi.org/10.30846/160808.

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Primary care physicians act as gatekeepers for patient referrals to specialist care, diagnosis and management advice, or when specialist procedures are needed. However, unexplained variations in referral rates by primary care physicians have been noted. Inappropriate referrals have negative implications for patients, for the costs of care and for healthcare systems. This summary describes the evidence on interventions to improve referrals from primary care to secondary care.

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Glasz, Kevin W. Leadership Implications of the Annual Patient Care Survey. Fort Belvoir, VA: Defense Technical Information Center, April 1999. http://dx.doi.org/10.21236/ada389167.

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Jennings, Bonnie M. Patient Care Outcomes: Implications for the Military Health Services Systems. Fort Belvoir, VA: Defense Technical Information Center, May 1991. http://dx.doi.org/10.21236/ada235932.

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Ben-Jonathan, Nira. Antagonism of Taxol Cytotoxicity by Prolactin: Implications for Patient Resistance to Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ada468538.

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Johnson, Corey, Colton James, Sarah Traughber, and Charles Walker. Postoperative Nausea and Vomiting Implications in Neostigmine versus Sugammadex. University of Tennessee Health Science Center, July 2021. http://dx.doi.org/10.21007/con.dnp.2021.0005.

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Purpose/Background: Postoperative nausea and vomiting (PONV) is a frequent complaint in the postoperative period, which can delay discharge, result in readmission, and increase cost for patients and facilities. Inducing paralysis is common in anesthesia, as is utilizing the drugs neostigmine and sugammadex as reversal agents for non-depolarizing neuromuscular blockers. Many studies are available that compare these two drugs to determine if neostigmine increases the risk of PONV over sugammadex. Sugammadex has a more favorable pharmacologic profile and may improve patient outcomes by reducing PONV. Methods: This review included screening a total of 39 studies and peer-reviewed articles that looked at patients undergoing general anesthesia who received non-depolarizing neuromuscular blockers requiring either neostigmine or sugammadex for reversal, along with their respective PONV rates. 8 articles were included, while 31 articles were removed based on our exclusion criteria. These were published between 2014 and 2020 exclusively. The key words used were “neostigmine”, “sugammadex”, “PONV”, along with combinations “paralytic reversal agents and PONV”. This search was performed on the scholarly database MEDLINE. The data items were PONV rates in neostigmine group, PONV rates in sugammadex group, incidence of postoperative analgesic consumption in neostigmine group, and incidence of postoperative analgesic consumption in sugammadex group. Results: Despite numerical differences being noted in the incidence of PONV with sugammadex over reversal with neostigmine, there did not appear to be any statistically significant data in the multiple peer-reviewed trials included in our review, for not one of the 8 studies concluded that there was a higher incidence of PONV in one drug or the other of an y clinical relevance. Although the side-effect profile tended to be better in the sugammadex group than neostigmine in areas other than PONV, there was not sufficient evidence to conclude that one drug was superior to the other in causing a direct reduction of PONV. Implications for Nursing Practice: There were variable but slight differences noted between both drug groups in PONV rates, but it remained that none of the studies determined it was statically significant or clinically conclusive. This review did, however, note other advantages to sugammadex over neostigmine, including its pharmacologic profile of more efficiently reversing non-depolarizing neuromuscular blocking drugs and its more favorable pharmacokinetics. This lack of statistically significant evidence found within these studies consequentially does not support pharmacologic decision-making of one drug in favor of the other for reducing PONV; therefore, PONV alone is not a sufficient rationale for a provider to justify using one reversal over another at the current time until further research proves otherwise.

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Han, Yuyuan, Weiming Zhang, Qi yan Mo, Lu Han, and Sikai Nong. A meta-analysis of prognosis difference between adolescent and adult nasopharyngeal carcinoma. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0131.

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Review question / Objective: Clinical trials for young patients with nasopharyngeal carcinoma are very limited. because of the rarity of nasopharyngeal carcinoma in young patients, oncologists are forced to follow treatment guidelines developed for adults for adolescent nasopharyngeal carcinoma patients. This study examines the differences in outcomes between adolescent and adult nasopharyngeal carcinoma patients treated with the same regimen and has clinical implications for the treatment of adolescent nasopharyngeal carcinoma patients. P : Patients with nasopharyngeal carcinoma. I : Adolescents. C : Adults. O : 5-year overall survival (OS). S : case-control study. Condition being studied: Nasopharyngeal carcinoma. Clinical trials for young patients with nasopharyngeal carcinoma are very limited. because of the rarity of nasopharyngeal carcinoma in young patients, oncologists are forced to follow treatment guidelines developed for adults for adolescent nasopharyngeal carcinoma patients. This study examines the differences in outcomes between adolescent and adult nasopharyngeal carcinoma patients treated with the same regimen and has clinical implications for the treatment of adolescent nasopharyngeal carcinoma patients.

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Boyes, Allison, Jamie Bryant, Alix Hall, and Elise Mansfield. Barriers and enablers for older people at risk of and/or living with cancer to accessing timely cancer screening, diagnosis and treatment. The Sax Institute, July 2022. http://dx.doi.org/10.57022/ieoy3254.

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• Older adults have complex and unique needs that can influence how and when cancer is diagnosed, the types of treatment that are offered, how well treatment is tolerated and treatment outcomes. • This Evidence Check review identified 41 studies that specifically addressed barriers and enablers to cancer screening, diagnosis and treatment among adults aged 65 years and older. • Question 1: The main barriers for older people at risk of and/or living with cancer to access and participate in timely cancer screening relate to lack of knowledge, fear of cancer, negative beliefs about the consequences of cancer, and hygiene concerns in completing testing. The main enablers to participation in timely cancer screening include positive/helpful beliefs about screening, social influences that encourage participation and knowledge. • Question 2: The main barriers for older people at risk of and/or living with cancer to access and/or seek timely cancer diagnosis relate to lack of knowledge of the signs and symptoms of cancer that are distinct from existing conditions and ageing, healthcare accessibility difficulties, perceived inadequate clinical response from healthcare providers, and harmful patient beliefs about risk factors and signs of cancer. The main enablers to accessing and/or seeking a timely cancer diagnosis include knowledge of the signs and symptoms of cancer, and support from family and friends that encourage help-seeking for symptoms. • Question 3: The main barriers for older people at risk of and/or living with cancer in accessing and completing cancer treatment include discrimination against patients in the form of ageism, lack of knowledge, patient concern about the adverse effects of treatment, predominantly on their independence, healthcare accessibility difficulties including travel and financial burden, and patients’ caring responsibilities. The main enablers to accessing and completing cancer treatment are social support from peers in a similar situation, family and friends, the influence of healthcare providers, and involving patients in treatment decision making. • Implications. The development of strategies to address the inequity of cancer outcomes in people aged 65 years and older in NSW should consider: Increasing community members’ and patients’ knowledge and awareness by providing written information and decision support tools from a trusted source Reducing travel and financial burden by widely disseminating information about existing support schemes and expanding remote patient monitoring and telehealth Improving social support by promoting peer support, and building the support capacity of family carers Addressing ageism by supporting patients in decision making, and disseminating education initiatives about geriatric oncology to healthcare providers Providing interdisciplinary geriatric oncology care by including a geriatrician as part of multidisciplinary teams and/or expanding geriatric oncology clinics.

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Desai, Heet, Mithum Senaratne, Shivling Swami, Soe Lwin Aye, and Yash Trivedi. Implications of Pimavanserin in Patients with Dementia‐related Psychosis: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2024. http://dx.doi.org/10.37766/inplasy2024.3.0089.

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