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Статті в журналах з теми "Hormonothérapies de nouvelle génération"
Berdah, J., O. Alenda, M. Martin, F. Combes, S. Benadiba, F. Jean, and J. Dumotier. "Hormonothérapies de nouvelle génération chez le patient de plus de 80 ans – À propos de 65 cas consécutifs." Progrès en Urologie 30, no. 13 (November 2020): 743. http://dx.doi.org/10.1016/j.purol.2020.07.089.
Повний текст джерелаScailteux, L. M., J. Bezin, M. Gundelwein, J. Edeline, E. Oger, F. Balusson, and A. Pariente. "Hormonothérapie de nouvelle génération dans le cancer de prostate et risque de second cancer primitif." Progrès en Urologie - FMC 34, no. 7 (November 2024): S90—S91. http://dx.doi.org/10.1016/j.fpurol.2024.07.126.
Повний текст джерелаDariane, C. "Prise en charge du cancer de prostate résistant à la castration (CPRC) non métastatique (M0) à l’ère des hormonothérapies de nouvelle génération et des imageries métaboliques." Progrès en Urologie - FMC 29, no. 4 (December 2019): F98—F104. http://dx.doi.org/10.1016/j.fpurol.2019.09.002.
Повний текст джерелаDenis, Claude. "Nouvelle génération." International Journal of Canadian Studies 58 (April 1, 2021): 4–6. http://dx.doi.org/10.3138/ijcs.58.x.4.
Повний текст джерелаPrauthois, Lus. "Familles. Nouvelle génération." Revue des politiques sociales et familiales 139-140, no. 2 (August 9, 2021): 113–15. http://dx.doi.org/10.3917/rpsf.139.0113.
Повний текст джерелаGessay, Jean-Claude, and Hedi Sellami. "Fraise nouvelle génération." Revue Française de Génie Civil 6, sup1 (January 2002): 77–84. http://dx.doi.org/10.1080/12795119.2002.9692429.
Повний текст джерелаclaire, Les Marie pas, and Anne Dhoquois. "Nouvelle génération, nouvelles féministes ?" Les cahiers du CEDREF, no. 4-5 (July 1, 1995): 149–70. http://dx.doi.org/10.4000/cedref.305.
Повний текст джерелаCottraux, Jean. "TCC, la nouvelle génération." Sciences Humaines N° Hors-série, HS10 (November 1, 2021): 49–51. http://dx.doi.org/10.3917/sh.hs10.0049.
Повний текст джерелаCottraux, Jean. "TCC, la nouvelle génération." Les Grands Dossiers des Sciences Humaines N°15, no. 6 (June 1, 2009): 23. http://dx.doi.org/10.3917/gdsh.452.0023.
Повний текст джерелаC.L. "Des clones nouvelle génération." Biofutur 2000, no. 197 (February 2000): 11. http://dx.doi.org/10.1016/s0294-3506(00)88124-7.
Повний текст джерелаДисертації з теми "Hormonothérapies de nouvelle génération"
Nicola, Celeste. "Thérapies du cancer de nouvelle génération et fonctions cognitives : Nouveaux concepts, nouveaux mécanismes, biomarqueurs originaux." Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMR050.
Повний текст джерелаAdvances in oncology have considerably improved the overall survival of cancer patients, thus understanding their toxicities and cerebral impacts is a major issue to maintain patients' quality of life (QoL). Certain cancer treatments can indeed lead to cognitive dysfunctions referred to as "cancer related cognitive impairment" (CRCI), which can impair Qol and compromise the autonomy of elderly patients. In this thesis work, we leverage preclinical models to decipher the direct impact of new-generation hormone therapies used in prostate cancer and of immunotherapies in the immune and inflammatory context linked to cancers, in the occurrence of cognitive, and/or emotional deficits as well as "fatigue". In a first study, we demonstrated the impact of the hormone therapies Enzalutamide and Abiraterone Acetate/Prednisone on exploration activity and spatial learning, in relation to brain altered dopaminergic transmission. In a second work, we showed that systemic inflammation, blood-brain barriers permeability accompanying meningeal infiltration of peripheral macrophages and neuroinflammation as well as deficits in cognition or emotional reactivity, depending on immuno-inflammatory or immune-desert cancer type. Combined with cancers, anti-PD-1 or -PD-L1 treatments exacerbate the decline in executive functions, while PD-L1 specifically relays the infiltration of a lymphocyte subpopulation in meninges implicated in cognitive deficits and anxiety. This work proposes new systemic biomarkers and original ways of intervention to improve the cancer patients QoL treated with new-generation therapies
Boue, Antoine. "Ιmpact cοgnitif des hοrmοnοthérapies du cancer de la prοstate : changements cοgnitifs οbjectifs et subjectifs cοnsécutifs à la déprivatiοn andrοgénique seule οu assοciée à une hοrmοnοthérapie de nοuvelle génératiοn". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC414.
Повний текст джерелаAndrogen deprivation is a standard-of-care option for advanced prostate cancer. New androgen receptor pathway inhibitors have been developed for patients with castration resistance. Among them, enzalutamide and abiraterone acetate are used for the treatment of metastatic prostate cancer in combination with androgen deprivation therapy. Androgen deprivation alone is known to impact cognition. Elderly patients, who represent the majority of prostate cancer patients, are at higher risk of cognitive impairment. In these patients, cognitive impairment can affect their autonomy and the course of care.This thesis aimed to evaluate the cognitive impact of hormone therapy for prostate cancer. A meta-analysis was conducted to identify the cognitive domains most affected by these treatments. It revealed a decline in subjective cognition (self-perceived cognition assessed with questionnaire) during androgen deprivation therapy alone or in combination with next-generation hormone therapy. In addition, a study was conducted with patients aged 70 and older, treated with enzalutamide or abiraterone acetate for metastatic castration-resistant prostate cancer. Before treatment, these patients exhibited frequent cognitive impairment. The addition of enzalutamide or abiraterone acetate to androgen deprivation therapy impacted both objective (processing speed and attention, assessed with cognitive tests) and subjective cognition
Richard, Julien. "Développement d’accumulateur nouvelle génération Mg ion." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAI125/document.
Повний текст джерелаThis PhD thesis aims to develop Mg-Ion cathode materials. Once the electrolyte selected and the electrochemical characterization system established, two insertion materials families were studied: Chevrel phases and manganese dioxides.The Chevrel phases Mo6S8 and Mo6Se8 have been the subject of a coupled electrochemistry / XPS ex situ understanding study. The two phases were characterized by voltammetry, GITT and PITT showing diffusion coefficients ranging from 10-11 to 10-14 cm2.s-1. Unconventional redox mechanisms were observed by XPS studies indicating a charge transfer inside the anions in addition to the reduction of the transition metals. The comparison of the two materials Mo6S8 and Mo6Se8 indicates the sulfur is more involved in the charge transfer than the selenium.In the second part, two MnO2 promising structures have been selected and studied: hollandite and birnessite. We evidenced that electrolyte hydratation is needed to allow the insertion inside the different MnO2 structures. RMN 1H and XPS analyses revealed a co-insertion phenomenon involving Mg2+ cations and H2O molecules. However, these compounds exhibit a poor cyclability and irreversible capacities of 50% to 80%. This understanding work is a first step towards the design of new reversible insertion materials for Mg-Ion batteries
Vivès, Sébastien. "La nouvelle génération de coronographes solaires." Aix-Marseille 1, 2004. http://www.theses.fr/2004AIX11048.
Повний текст джерелаLacourcière, Roxanne. "Dissidence : pour une nouvelle génération de résistance." Master's thesis, Université Laval, 2014. http://hdl.handle.net/20.500.11794/25326.
Повний текст джерелаIssindou, Valentin. "Matériaux magnétostrictifs de nouvelle génération pour l’énergie." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAT083/document.
Повний текст джерелаIn recent years, performances of multiferroïc materials have considerably improved with two-phase composites: magnetostrictive and piezoelectric. These composites take advantage of the coupling between magnetism and piezoelectricity through magnetostriction. Thus they allow control of magnetization with electrical voltage, and conversely, to get an electrical polarization depending on the magnetic field (our focus in this case). This drives electronics towards more environmental friendly solutions, namely with lower circuit power consumption (current controls are replaced by voltage controls) and the replacement of batteries, which must be periodically changed, by sustainable energy harvesting systems. Energy harvesting solutions are popular with the Internet of Things (IoT). Despite their performance, these multiferroïc composites remain perfectible, especially regarding the magnetostrictive phase. Its optimization is essential. The common material is Terfenol-D because of its giant magnetostriction, used in its massive and monocrystalline form. This material remains rare, expensive, fragile and its growing method is not adapted to the manufacturing of miniature devices. This work focuses on a comparative study of Terfenol-D miniature disk manufacturing pathways for the production of energy harvesters. A benchmark study was carried out on a series of disks cut in commercial alloy ingots (monocrystalline and polycrystalline). Next, the isotropic powder sintering method was investigated with very little background on this material. Conventional sintering led to the first functional disks needing no ulterior machining but with low density and mechanical strength. These defects were then corrected using the SPS technique (Spark Plasma Sintering) but the reproducibility over time has yet to be improved. The Terfenol-D disks (both cut and manufactured) were assembled with the piezoelectric phase (commercial PZT). Electrical characterizations using a contactless method have validated their potential to harvest energy, in lesser amounts than monocrystalline Terfenol-D as expected, but in a large enough quantity regarding most of applications. Finally, an alternative solution has been explored with NiMnGa shape magnetic alloys offering very large deformations. A perspective to a wireless autonomous push button prototype is presented at the very end
Maachaoui, Mohamed. "Sécurité et performances des réseaux de nouvelle génération." Phd thesis, Toulouse, INPT, 2015. http://oatao.univ-toulouse.fr/14266/1/Maachaoui.pdf.
Повний текст джерелаBecker, Pierre. "Développement d'une interaction nucléaire effective de nouvelle génération." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1153/document.
Повний текст джерелаThe nucleus may seem well known, but its microscopic description still isn't perfect. Describing accurately the nuclei along the nuclear chart remain complicated.Nowadays, the effective interactions are the best choice to achieve such a goal, and can be sorted in two categories: finite-range and zero-range. Skyrme interaction, the main subject of this report, belongs to the latter. Used since the 50s because of its simplicity, it is an expansion of gradients up to the 2th order. However, an international collaboration, UNEDF, showed recently that this interaction was too limited to describe all the nuclear constraints given by experimental datas. The conclusion was the necessity of Skyrme interaction extensions.This thesis is describing the process from the design of the interaction to its use in nuclei and in fitting procedures.First, we review the requirements and the construction of a general nuclear interactions, and the main interactions used in nuclear structure, both finite and zero range.We then show the behaviour of these interactions in a perfect model: the infinite nuclear matter. This is considered a preliminary test for every interaction aiming to describe nuclei, and the performances of our interactions are discussed, along the performances of the other models.The last part of the thesis is the adaptation of our extension for calculations of nuclei. Furthermore, the fitting procedure of our extended Skyrme interaction on both infinite nuclear matter and nuclei quantities is detailed. A resulting parametrisation is presented at the end of the thesis, aiming to describe more accurately the nuclear chart and the additional physic provided by the new terms
Broussard, Elliot. "Commande innovante d’une nouvelle génération d’antenne satellite mobile." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEI090.
Повний текст джерелаIn military and civil application, satellite communications (SACTOM) are often needed on moving vehicles (drones, planes, land vehicles, vessels…) in order to transfer all kind of data (pictures, videos, internet …). These types of stations are called SATCOM On The Move (SOTM). In order insure high data rates, the antenna must be directional, which means that they direct electro-magnetic waves in a particular direction of space, called line of sight. The line of sight must be steered in order to be aligned with the satellite to insure a strong communication link with the highest data rate possible. Stabilized platforms, called Antenna Positioning System, aim to steer the antenna’s line of sight in the satellite direction. The pointing requirements are the source of conception constraints that reduce the cost efficiency of the overall station. This PhD report focus on the development and the study of a new pointing strategy called Helios (“Hybrid Estimator of LIne Of Sight”). This algorithm uses least squares to found the antenna pattern in real time, using an observation window. Among others, it allows to reduce the bandwidth of the control loops by generating a trajectory easier to follow. Therefore, it decreases the conception constraints (friction, backlash, field bus data rate …). Helios is tested through experimentation, using Thales industrial prototypes. The vehicle is emulated by a hexapod. Simulation is carried out in order to fit the measured experimental behavior. To do so, parametrical and non-parametrical identification has been done on the SOTM prototype. This way, Helios is validated and studied in operational conditions
Burner, Pauline. "Nouvelle génération de luminophores pour l'éclairage par LED." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAI064/document.
Повний текст джерелаWhite solid state lighting is recognized as a major disruptive technology with an urgent need of low coast prices, associated to good color quality, confortable for eyes, by reducing the bluish harmful contribution of “cold” lighting. At Néel Institute, we develop a new type of phosphors based on yttrium aluminoborate powders. These innovating powders exhibit a large emission band on the whole visible range, arising from structural defects in the amorphous matrix. Thus, with a single phosphor, one can generate warm white lighting through the excitation of LEDs emitting in the near UV (370-390 nm). Moreover, these phosphors don’t possess lanthanides, making them less expensive.The powders synthesized by chimie douce routes, are annealed under controlled atmosphere. The yttrium alominoborate phosphors were first prepared by the polymercic precursor method. This synthesis road involved several steps and relatively high annealing temperatures (700-740°C). This thesis was focused on the sol-gel synthesis method. By this work, the duration process, the annealing temperature (450°C-650°C), and the global mass loss incoming from the organic precursors decomposition were significantly reduced.Thermal analysis (TDA-TG) coupled with mass spectrometry and 13C RNM show residual carbon groups in luminescent powders. Nevertheless, one part of the residual carbons is pyrolytic carbon (aromatic carbon), which leads to partial re-absorption of the visible emitted luminescence, and thus induces a decrease of the emission intensity.The structural characterizations of yttrium aluminoborate powders (XRD, FTIR, NMR) show that Al4B2O9 aluminoborate phase, is the first appearing crystalline phase during the increase of calcination temperature. The Pair Distribution Function (PDF) study demonstrates that amorphous aluminoborate matrix exhibit a short range ordering close to Al4B2O9 phase: a cyclic tridimensional organization of metal bridges by oxo or hydroxo ligands. On the other hand, based on 13C NMR results, yttrium seems to conserve propionate ligands in its coordination sphere until high temperature. Otherwise, the presence of radical species was evidenced in luminescent powders by electronic paramagnetic resonance. A set of measurements performed at different frequencies, in continuous and pulsed modes, allows attributing that species to carbon radicals. The presence of several luminescence species exhibiting essentially fluorescence properties (ns life time) and very weak phosphorescence emission (ms and s lifetime) was shown by the means of photoluminescence studies steady-state and time resolved coupled to thermoluminescence analysis. The powders synthesized by sol-method exhibit a 30 % internal quantum yield.Thanks to the different characterizations, luminescent powders synthesized by the sol-gel route seem to contain two types of residual carbons: one at the origin of the luminescence properties (carbon-related radicals) while the other, pyrolytic carbon, is damaging as it absorbs partially the luminescence emission. To conclude, we suggest an extrinsic mechanism for the photoluminescence, which is based on carbon centers dispersed inside the mineral matrix, favoring mainly fluorescence in blue (430 nm) and green emissions (500 nm) associated with a weak phosphorescence emission in the same emission range
Книги з теми "Hormonothérapies de nouvelle génération"
Roux, Sébastien, and Anne-Sophie Vozari. Familles: Nouvelle génération. Paris: PUF, 2020.
Знайти повний текст джерелаMichelle, Lamoreaux, and Lamoreaux Robert, eds. SpieZ! nouvelle génération: En route pour les ennuis. [Paris]: Pocket jeunesse, 2010.
Знайти повний текст джерела1952-, Guerraoui Driss, ed. L'élite économique marocaine: Étude sur la nouvelle génération d'entrepreneurs. Paris: Harmattan, 2009.
Знайти повний текст джерелаGérard, Jean-Louis. Infirmiers en psychiatrie: Nouvelle génération : une formation en question. Paris: Lamarre, 1993.
Знайти повний текст джерелаFerrand, Olivier. L'Europe contre l'Europe: Appel à une nouvelle génération européenne. Paris: Hachette littératures, 2009.
Знайти повний текст джерелаAssemblée de L'Atlantique Nord. Commission des Affaires Sociales. Rapport Final de la Sous-Commission sur la Nouvelle Génération. S.l: s.n, 1985.
Знайти повний текст джерелаFaure, Olivier, and Lucile Schmid. Le bruit du tic-tac: Une nouvelle génération en politique. Paris: Laffont, 2001.
Знайти повний текст джерелаSubaie, Mohammad Al. L'idéologie de l'islamisme radical: La nouvelle génération des intellectuels islamistes. Paris: L'Harmattan, 2012.
Знайти повний текст джерелаLevasseur, J. F. Adrien. Pierre Levasseur dit Lespérance et la première génération en Nouvelle-France. Longueuil [Québec]: J.-F.-A. Levasseur, 1989.
Знайти повний текст джерела1942-, Posterski Donald C., ed. La nouvelle génération: Les opinions des jeunes du Canada sur leurs valeurs. Montréal, Qué: Fides, 1986.
Знайти повний текст джерелаЧастини книг з теми "Hormonothérapies de nouvelle génération"
Bizien Filippi, Myriam. "Chapitre VIII. L’apparition d’une « nouvelle génération de musulmans » ?" In Accommodements religieux, 161–84. Rennes: Presses universitaires de Rennes, 2024. http://dx.doi.org/10.4000/12hcf.
Повний текст джерела"Naissance d’une nouvelle génération intellectuelle." In Génération MBC., 21–42. Presses de l'Université Laval, 2022. http://dx.doi.org/10.2307/j.ctv30dxxbj.5.
Повний текст джерела"Naissance d’une nouvelle génération intellectuelle." In Génération MBC, 21–42. Les Presses de l’Université de Laval, 2022. http://dx.doi.org/10.1515/9782763759081-003.
Повний текст джерелаCottraux, Jean. "TCC, la nouvelle génération." In Troubles mentaux et psychothérapies, 199. Editions Sciences Humaines, 2016. http://dx.doi.org/10.3917/sh.marmi.2016.01.0199.
Повний текст джерела"Libre-échange [nouvelle génération]." In La politique étrangère contemporaine en bons termes, 64. Presses de l'Université du Québec, 2016. http://dx.doi.org/10.1515/9782760546516-049.
Повний текст джерелаLenoble-Bart, Annie. "3. Une nouvelle génération de chefs d'état." In Afrique Nouvelle, 263–73. Maison des Sciences de l’Homme d’Aquitaine, 1996. http://dx.doi.org/10.4000/books.msha.14373.
Повний текст джерелаSchneider, Nicola. "Former une nouvelle génération de nonnes." In Le renoncement au féminin, 215–36. Presses universitaires de Paris Nanterre, 2013. http://dx.doi.org/10.4000/books.pupo.3563.
Повний текст джерелаMercier, Valentine. "Les dynamiques internes d’une nouvelle génération." In Mouvements féminins et Parti communiste au Brésil (1945-1961), 101–3. Éditions de l’IHEAL, 2020. http://dx.doi.org/10.4000/books.iheal.9052.
Повний текст джерелаÔchi, Fukuchi, Suehiro Tetchô, and Tokutomi Sohô. "Tokutomi Sohô – la « nouvelle génération » de journalistes." In Du sabre à la plume, 41–75. Presses universitaires de Strasbourg, 2014. http://dx.doi.org/10.4000/books.pus.5805.
Повний текст джерелаGRASLIN, A., R. DUPONT, O. CHABERT, Ph ROUANET DE BERCHOUX, and P. DERAIN. "Du concept à la réalisation." In Médecine et Armées Vol. 45 No.2, 103–12. Editions des archives contemporaines, 2017. http://dx.doi.org/10.17184/eac.7421.
Повний текст джерелаТези доповідей конференцій з теми "Hormonothérapies de nouvelle génération"
Michel, Stéphane. "Outil nouvelle génération d'analyse du soutien logistique." In Congrès Lambda Mu 20 de Maîtrise des Risques et de Sûreté de Fonctionnement, 11-13 Octobre 2016, Saint Malo, France. IMdR, 2016. http://dx.doi.org/10.4267/2042/61730.
Повний текст джерелаSTASSEN, Yves, François LESNE, Yves ROBIN, and Simon HOFLACK. "Appontements flottants de nouvelle génération pour l'accueil des frégates multi-missions (FREMM)." In Journées Nationales Génie Côtier - Génie Civil. Editions Paralia, 2010. http://dx.doi.org/10.5150/jngcgc.2010.084-s.
Повний текст джерелаLefort, Claire, Mathieu Chalvidal, Alexis Parenté, Véronique BLANQUET, Henri Massias, Laetitia MAGNOL, and Emilie Chouzenoux. "Imagerie 3D par microscopie multiphotonique appliquée aux sciences du vivant : la chaine instrumentale et computationnelle FAMOUS." In Les journées de l'interdisciplinarité 2022. Limoges: Université de Limoges, 2022. http://dx.doi.org/10.25965/lji.221.
Повний текст джерелаBerselli, Silvia. "Une correspondance architecturale: Ionel Schein "enfant" de Le Corbusier." In LC2015 - Le Corbusier, 50 years later. Valencia: Universitat Politècnica València, 2015. http://dx.doi.org/10.4995/lc2015.2015.1042.
Повний текст джерелаЗвіти організацій з теми "Hormonothérapies de nouvelle génération"
Fontecave, Marc, and Candel Sébastien. Quelles perspectives énergétiques pour la biomasse ? Académie des sciences, January 2024. http://dx.doi.org/10.62686/1.
Повний текст джерелаInitiative géoscientifique ciblée : accroître l'efficacité de l'exploration en profondeur grâce à la science et à l'innovation de la nouvelle génération. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2019. http://dx.doi.org/10.4095/315701.
Повний текст джерелаEn contexte : comprendre les soins de maternité au Canada. L’Institut Vanier de la famille, 2017. http://dx.doi.org/10.61959/vlvm8981f.
Повний текст джерела