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Статті в журналах з теми "Hippocampal CA3"
Ang, Mary Jasmin, Sueun Lee, Mai Wada, Poornima D. E. Weerasinghe-Mudiyanselage, Sung-Ho Kim, Taekyun Shin, Tae-Il Jeon, Seung-Soon Im, and Changjong Moon. "SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice." International Journal of Molecular Sciences 22, no. 11 (June 5, 2021): 6103. http://dx.doi.org/10.3390/ijms22116103.
Повний текст джерелаŚwietlik, Dariusz, Jacek Białowąs, Janusz Moryś, Ilona Klejbor, and Aida Kusiak. "Computer Modeling of Alzheimer’s Disease—Simulations of Synaptic Plasticity and Memory in the CA3-CA1 Hippocampal Formation Microcircuit." Molecules 24, no. 10 (May 17, 2019): 1909. http://dx.doi.org/10.3390/molecules24101909.
Повний текст джерелаŚwietlik, Dariusz, Jacek Białowąs, Janusz Moryś, Ilona Klejbor, and Aida Kusiak. "Effects of Inducing Gamma Oscillations in Hippocampal Subregions DG, CA3, and CA1 on the Potential Alleviation of Alzheimer’s Disease-Related Pathology: Computer Modeling and Simulations." Entropy 21, no. 6 (June 13, 2019): 587. http://dx.doi.org/10.3390/e21060587.
Повний текст джерелаBlom, Kim, Huiberdina L. Koek, Maarten H. T. Zwartbol, Rashid Ghaznawi, Hugo J. Kuijf, Theo D. Witkamp, Jeroen Hendrikse, Geert Jan Biessels, and Mirjam I. Geerlings. "Vascular Risk Factors of Hippocampal Subfield Volumes in Persons without Dementia: The Medea 7T Study." Journal of Alzheimer's Disease 77, no. 3 (September 29, 2020): 1223–39. http://dx.doi.org/10.3233/jad-200159.
Повний текст джерелаZapukhliak, O. S., O. V. Netsyk, and D. S. Isaev. "SYNCHRONIZATION OF EPILEPTIFORM ACTIVITY BETWEEN CA1 AND CA3 HIPPOCAMPAL FIELDS UNDER SYNAPTIC AND NON-SYNAPTIC CONDITIONS IN RAT BRAIN SLICES." Medical Science of Ukraine (MSU) 16, no. 1 (February 28, 2020): 3–7. http://dx.doi.org/10.32345/2664-4738.1.2020.01.
Повний текст джерелаZapukhliak, Olha, Olga Netsyk, Artur Romanov, Oleksandr Maximyuk, Murat Oz, Gregory L. Holmes, Oleg Krishtal, and Dmytro Isaev. "Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors." PLOS ONE 16, no. 3 (March 12, 2021): e0240074. http://dx.doi.org/10.1371/journal.pone.0240074.
Повний текст джерелаWu, Chiping, Marjan Nassiri Asl, Jesse Gillis, Frances K. Skinner, and Liang Zhang. "An In Vitro Model of Hippocampal Sharp Waves: Regional Initiation and Intracellular Correlates." Journal of Neurophysiology 94, no. 1 (July 2005): 741–53. http://dx.doi.org/10.1152/jn.00086.2005.
Повний текст джерелаNwaubani, P., A. Colasanti, M. Cercignani, and A. Warner. "MRI Analysis: Optimization of parameters for diffusion MRI to enhance hippocampal subfield analysis and segmentation (Preliminary Data)." European Psychiatry 65, S1 (June 2022): S638. http://dx.doi.org/10.1192/j.eurpsy.2022.1637.
Повний текст джерелаStojanovic, Tamara, David Velarde Gamez, Gabor Jorrid Schuld, Daniel Bormann, Maureen Cabatic, Pavel Uhrin, Gert Lubec, and Francisco J. Monje. "Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes." Cells 11, no. 2 (January 13, 2022): 261. http://dx.doi.org/10.3390/cells11020261.
Повний текст джерелаDaugherty, Ana M., Hillary D. Schwarb, Matthew D. J. McGarry, Curtis L. Johnson, and Neal J. Cohen. "Magnetic Resonance Elastography of Human Hippocampal Subfields: CA3-Dentate Gyrus Viscoelasticity Predicts Relational Memory Accuracy." Journal of Cognitive Neuroscience 32, no. 9 (September 2020): 1704–13. http://dx.doi.org/10.1162/jocn_a_01574.
Повний текст джерелаДисертації з теми "Hippocampal CA3"
Kyle, Colin T., and Colin T. Kyle. "Cytoarchitectonically-Driven MRI Atlas of the Hippocampus and the Behavioral Impact of Neural Recording Devices: Addressing Methodological Concerns for Studies of Age-Related Change in Hippocampal Subfields." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/625684.
Повний текст джерелаBecker, Nadine. "Imaging activity-dependent structural and functional plasticity of hippocampal CA3-CA1 synapses." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-101290.
Повний текст джерелаStevenson, Cassie Hayley. "Investigating the role of the hippocampal formation in episodic and spatial memory." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5632.
Повний текст джерелаZhang, Pei. "Synaptic modifications in hippocampal CA3 pyramidal cells in an Alzheimer's mouse model." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0628/document.
Повний текст джерелаMemory encoding is thought to proceed from durable changes in the activity of synaptic circuits to the storage of patterns of electrical events in a sparsely distributed ensemble of neurons. Located at the entry level of hippocampal circuitry, the CA3 region of hippocampus is thought to be important for episodic memory encoding, especially at the initial stage of acquisition, by presumably developing an instant representation of a context. CA3 pyramidal neurons receive a variety of diverse inputs, among which the mossy fiber (MF) inputs draw special attention for its peculiar structure and unique synaptic properties. However, the links between the plasticity of CA3 circuits and memory encoding are not well understood.This thesis project aimed to address the synaptic mechanisms of episodic memory encoding in physiological conditions as well as in a mouse model of Alzheimer's disease (AD).Using electrophysiological recording techniques, we first explored the changes in CA3 circuits shortly after one-trial contextual fear conditioning in adult C57Bl6j mice. We show that despite hardly any changes in filopodia number of MF terminals, an increase in spontaneous IPSC frequency can be registered, while the EPSCs and short-term plasticities of theses synapses are unaltered. However, this increase cannot be seen anymore 24 hours after the contextual learning. We also tried to do simplified computational modeling of the DG-CA3 neuronal networks, to investigate if and to what extent the local interneurons in CA3 region contribute to memory encoding precision.AD is characterized at an early stage by impaired episodic memory, which may involve dysregulation of the plasticity of CA3 circuits.In the next step, we searched for synaptic deficits in CA3 local circuit in the early stage of AD pathology, taking advantage of a familial AD mouse model: 6-month male APP/PS1 mice. We report that there is a reduction in spontaneous IPSC frequency in CA3 neurons together with decreased inhibitory charges of evoked events at MF-CA3 synapses, whereas the short-term plasticity of these synapses and intrinsic properties of CA3 neurons remain unaffected. Furthermore, there is a robust reduction in Kainate receptor (KAR) mediated currents at MF-CA3 synapses, and the same results can be obtained from PSKO mice too, suggesting that disturbed function of γ-secretase and NCad processing pathways might underlie the dysfunction of KARs at MF-CA3 synapses.Finally, to screen for changes on a transcriptome level, we performed RNA-seq with dissected CA3 tissue from APP/PS1 mice and found a list of up- and down-regulated genes at this early stage of AD. Moreover, we carried out ChIP-seq for a histone modification marker: H3K4me3, which has been shown to be directly related to one-trial contextual memory, and here we report that there is a concrete decrease in H3K4me3 levels at the promoter areas of various genes in CA3 neurons. However, these genes are not overlapping much with the down-regulated genes from RNA-seq result, suggesting that other epigenetic mechanisms might play more important roles in expressing early deficits in this AD mouse model.Taken together, we show that inhibitory innervations of hippocampal CA3 local circuits might be important for episodic memory encoding, and in early AD mouse model with memory deficits, there is reduced GABAergic transmission and reduced KAR-mediated currents in CA3 neurons, together with many active transcriptional regulations across the genome. Our study might contribute to the understanding of early AD pathologies at synaptic level as well as transcriptional level, and provide novel insights into the mechanisms underlying rapid encoding of contextual memory
LICHERI, VALENTINA. "Modulation of Hyperpolarization-Activated Cation Currents (Ih) by Ethanol in Rat Hippocampal CA3 Pyramidal Neurons." Doctoral thesis, Università degli Studi di Cagliari, 2015. http://hdl.handle.net/11584/266622.
Повний текст джерелаCanepari, Marco. "Intrinsic variability and short-term changes in synaptic transmission in the rat hippocampal CA3 region." Doctoral thesis, SISSA, 1999. http://hdl.handle.net/20.500.11767/4432.
Повний текст джерелаKanak, Daniel James. "Influence of perforant path synaptic excitation on the initiation of hippocampal sharp-wave ripple activity in vitro." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/dissertations/776.
Повний текст джерелаDennis, Siobhan Dennis. "An investigation of the effects of oxygen glucose deprivation on glutamate receptor localisation within hippocampal CA3 pyramidal neurons." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544384.
Повний текст джерелаCaiati, Maddalena Delma. "Activity-dependent regulation of GABA release at immature mossy fibers-CA3 synapses: role of the Prion protein." Doctoral thesis, SISSA, 2012. http://hdl.handle.net/20.500.11767/4719.
Повний текст джерелаZhang, Pei [Verfasser], André [Akademischer Betreuer] Fischer, Helene [Gutachter] Marie, Lionel [Gutachter] Dahan, Yoon [Gutachter] Cho, and Christophe [Gutachter] Mulle. "Synaptic modifications in hippocampal CA3 pyramidal cells in an Alzheimer's mouse model / Pei Zhang ; Gutachter: Helene Marie, Lionel Dahan, Yoon Cho, Christophe Mulle ; Betreuer: André Fischer." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2018. http://d-nb.info/1153607174/34.
Повний текст джерелаКниги з теми "Hippocampal CA3"
Ouanounou, Aviv. Modulation of synaptic transmission by exogenous calcium buffers in hippocampal CA1 neurons. Ottawa: National Library of Canada, 1996.
Знайти повний текст джерелаPawluski, Jodi Lynn. Primiparous rats, but not multiparous rats, exhibit dendritic atrophy in CA1 and CA3 pyramidal cells of the hippocampus. Ottawa: National Library of Canada, 2003.
Знайти повний текст джерелаBreakwell, Nicholas Anthony. A1F[inferior 4]-induced synaptic plasticity in area CA1 of rat hippocampus. Birmingham: University of Birmingham, 1995.
Знайти повний текст джерелаWrong, Andrew D. Bimodal modulation of N-methyl-D-aspartate-induced currents in rat CA1 hippocampal neurons by kainate application. Ottawa: National Library of Canada, 2002.
Знайти повний текст джерелаJazayeri, Mehrdad. A theoretical investigation of the generation of a spontaneous slow rhythm in hippocampus Ca1. Ottawa: National Library of Canada, 2001.
Знайти повний текст джерелаDorri, Faramarz. Antisense deoxyoligonucleotide inhibitation of metabotropic glutamate receptor 5 synthesis in CA1 area of rat hippocampus. Ottawa: National Library of Canada, 1995.
Знайти повний текст джерелаDonegan, Macayla. Coding of social novelty in the hippocampal Cornu Ammonis 2 region (CA2) and its disruption and rescue in a mouse model of schizophrenia. [New York, N.Y.?]: [publisher not identified], 2020.
Знайти повний текст джерелаSong, Dong, and Theodore W. Berger. Hippocampal memory prosthesis. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0055.
Повний текст джерелаBeninger, Richard J. Multiple memory systems. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198824091.003.0004.
Повний текст джерелаMaren, Stephen. Neural Circuits for Context Processing in Aversive Learning and Memory. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0005.
Повний текст джерелаЧастини книг з теми "Hippocampal CA3"
Graham, Bruce P., Vassilis Cutsuridis, and Russell Hunter. "Associative Memory Models of Hippocampal Areas CA1 and CA3." In Hippocampal Microcircuits, 459–94. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0996-1_16.
Повний текст джерелаMigliore, Michele, Giorgio A. Ascoli, and David B. Jaffe. "CA3 Cells: Detailed and Simplified Pyramidal Cell Models." In Hippocampal Microcircuits, 353–74. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0996-1_12.
Повний текст джерелаSanjay, M., and Srinivasa B. Krothapalli. "Modelling Epileptic Activity in Hippocampal CA3." In Springer Series in Computational Neuroscience, 757–77. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-99103-0_22.
Повний текст джерелаSanjay, M., and Srinivasa B. Krothapalli. "Correction to: Modelling Epileptic Activity in Hippocampal CA3." In Springer Series in Computational Neuroscience, C1. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99103-0_26.
Повний текст джерелаSamura, Toshikazu, Motonobu Hattori, and Shun Ishizaki. "Sequence Disambiguation by Functionally Divided Hippocampal CA3 Model." In Neural Information Processing, 117–26. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11893028_14.
Повний текст джерелаAitken, P. G., D. B. Jaffe, and J. V. Nadler. "Cholecystokinin and Epileptogenesis in the Hippocampal CA3 Region." In Physiology, Pharmacology and Development of Epileptogenic Phenomena, 103–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-46732-5_23.
Повний текст джерелаGranger, Richard, Makoto Taketani, and Gary Lynch. "Special Purpose Temporal Processing in Hippocampal Fields CA1 and CA3." In Neural Representation of Temporal Patterns, 183–95. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1919-5_8.
Повний текст джерелаCanepari, Marco, and Enrico Cherubini. "Dynamics of Transmitter Release at CA3 Hippocampal Excitatory Synapses." In Neural Circuits and Networks, 71–83. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-58955-3_5.
Повний текст джерелаZheng, Chenguang, Qun Li, Yiyi Wang, and Tao Zhang. "Theta Phase Time-Delayed Modulating Low Gamma Amplitude in Hippocampal CA3–CA1 Network." In Advances in Cognitive Neurodynamics (V), 259–65. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-0207-6_36.
Повний текст джерелаChitwood, Raymond A., Brenda J. Claiborne, and David B. Jaffe. "Modeling the Passive Properties of Nonpyramidal Neurons in Hippocampal Area CA3." In Computational Neuroscience, 59–64. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4757-9800-5_10.
Повний текст джерелаТези доповідей конференцій з теми "Hippocampal CA3"
Shiva, Ashraya Samba, Mandar Gogate, Newton Howard, Bruce Graham, and Amir Hussain. "Complex-valued computational model of hippocampal CA3 recurrent collaterals." In 2017 IEEE 16th International Conference on Cognitive Informatics & Cognitive Computing (ICCI*CC). IEEE, 2017. http://dx.doi.org/10.1109/icci-cc.2017.8109745.
Повний текст джерелаModak, Priyamvada, and V. Srinivasa Chakravarthy. "Izhikevich Models For Hippocampal Neurons And Its Sub-Region CA3." In 2018 Conference on Cognitive Computational Neuroscience. Brentwood, Tennessee, USA: Cognitive Computational Neuroscience, 2018. http://dx.doi.org/10.32470/ccn.2018.1189-0.
Повний текст джерелаLevy, William B., Kai S. Chang, and Andrew G. Howe. "Progressively introducing quantified biological complexity into a hippocampal CA3 model." In 2009 International Joint Conference on Neural Networks (IJCNN 2009 - Atlanta). IEEE, 2009. http://dx.doi.org/10.1109/ijcnn.2009.5178724.
Повний текст джерелаSong, Dong, Robert E. Hampson, Brian S. Robinson, Ioan Opris, Vasilis Z. Marmarelis, Sam A. Deadwyler, and Theodore W. Berger. "Nonlinear dynamical modeling of human hippocampal CA3-CA1 functional connectivity for memory prostheses." In 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2015. http://dx.doi.org/10.1109/ner.2015.7146623.
Повний текст джерелаWang, Peng, Xuewei Song, Xiyan Zhu, Jinlong Qiu, Shuaijun Yang, and Hui Zhao. "Study on Influencing Factors of Hippocampal Injury in Closed Head Impact Experiments of Rats Using Orthogonal Experimental Design Method." In WCX SAE World Congress Experience. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2023. http://dx.doi.org/10.4271/2023-01-0001.
Повний текст джерелаObregón-Herrera, Armando. "Biophysical Properties of ATP-sensitive Potassium Channels in CA3 Hippocampal Neurons." In MEDICAL PHYSICS: Eighth Mexican Symposium on Medical Physics. AIP, 2004. http://dx.doi.org/10.1063/1.1811873.
Повний текст джерелаKoene, Randal A., and Michael E. Hasselmo. "A reversing buffer mechanism that enables instances of retrospective activity in hippocampal regions CA3 and CA1." In 2007 International Joint Conference on Neural Networks. IEEE, 2007. http://dx.doi.org/10.1109/ijcnn.2007.4371163.
Повний текст джерелаDong Song, R. H. M. Chan, V. Z. Marmarelis, R. E. Hampson, S. A. Deadwyler, and T. W. Berger. "Estimation and statistical validation of event-invariant nonlinear dynamic models of hippocampal CA3-CA1 population activities." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090903.
Повний текст джерелаNejati, Alireza, and Charles P. Unsworth. "3-D Modeling of nitric oxide emission and vasodilation induced by CA3 hippocampal neurons." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090160.
Повний текст джерелаSamura, Toshikazu, Yasuomi D. Sato, Yuji Ikegaya, Hatsuo Hayashi, and Takeshi Aihara. "Diverse background activities hidden in power-law spontaneous activity of hippocampal CA3 slice culture." In 2012 Joint 6th Intl. Conference on Soft Computing and Intelligent Systems (SCIS) and 13th Intl. Symposium on Advanced Intelligent Systems (ISIS). IEEE, 2012. http://dx.doi.org/10.1109/scis-isis.2012.6505225.
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