Добірка наукової літератури з теми "GLS1"
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Статті в журналах з теми "GLS1":
Vidula, Neelima, Christina Yau, and Hope S. Rugo. "Glutaminase (GLS) expression in primary breast cancer (BC): Correlations with clinical and tumor characteristics." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 558. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.558.
Rojas, Livisu Pajares, and Claudia Machicado Rivero. "Abstract 883: Glutaminases expression and viral infection as potential prognostic factors in cervical, head and neck and liver cancers." Cancer Research 83, no. 7_Supplement (April 4, 2023): 883. http://dx.doi.org/10.1158/1538-7445.am2023-883.
Bright, Scott J., Rishab Kolachina, Mariam Ben Kacem, Mandira Manandhar, Philip Jones, Timothy A. Yap, Steven H. Lin, and Gabriel O. Sawakuchi. "Abstract B030: Modulating mitochondria metabolism to radiosensitize KEAP1 mutated non-small cell lung cancer." Cancer Research 84, no. 1_Supplement (January 9, 2024): B030. http://dx.doi.org/10.1158/1538-7445.dnarepair24-b030.
Xiao, Yangbo, Rong Huang, Shenping Cao, Dafang Zhao, Zhuangwen Mao, Chuchu Xiao, Zhehua Xu, et al. "Molecular Characterization and Dietary Regulation of Glutaminase 1 (gls1) in Triploid Crucian Carp (Carassius auratus)." Fishes 7, no. 6 (December 7, 2022): 377. http://dx.doi.org/10.3390/fishes7060377.
Myint, Zin W., Ramon C. Sun, Patrick J. Hensley, Andrew C. James, Peng Wang, Stephen E. Strup, Robert J. McDonald, Donglin Yan, William H. St. Clair, and Derek B. Allison. "Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters." Cancers 13, no. 9 (April 29, 2021): 2157. http://dx.doi.org/10.3390/cancers13092157.
Yang, Jianqiang, Fanghui Chen, Fan Yang, and Yong Teng. "Abstract 3061: A positive feedback loop between GLS1 and c-Myc drives tumor aggressiveness." Cancer Research 84, no. 6_Supplement (March 22, 2024): 3061. http://dx.doi.org/10.1158/1538-7445.am2024-3061.
Ahmed, Shanzay, Peter John, Rehan Zafar Paracha, Attya Bhatti, and Monica Guma. "Docking and Molecular Dynamics Study to Identify Novel Phytobiologics from Dracaena trifasciata against Metabolic Reprogramming in Rheumatoid Arthritis." Life 12, no. 8 (July 29, 2022): 1148. http://dx.doi.org/10.3390/life12081148.
Kono, Michihito, Nobuya Yoshida, Kayaho Maeda, and George C. Tsokos. "Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells." Proceedings of the National Academy of Sciences 115, no. 10 (February 20, 2018): 2478–83. http://dx.doi.org/10.1073/pnas.1714717115.
Beręsewicz-Haller, Małgorzata, Olga Krupska, Paweł Bochomulski, Danuta Dudzik, Anita Chęcińska, Wojciech Hilgier, Coral Barbas, Krzysztof Zablocki та Barbara Zablocka. "Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase". International Journal of Molecular Sciences 22, № 16 (7 серпня 2021): 8504. http://dx.doi.org/10.3390/ijms22168504.
Myint, Zin, Patrick J. Hensley, Andrew Callaway James, Peng Wang, Stephen Strup, Donglin Yan, William H. St Clair, Robert S. DiPaola, and Derek B. Allison. "Immunohistochemical evaluation of glutaminase expression in prostate adenocarcinoma and correlation with clinicopathologic parameters." Journal of Clinical Oncology 39, no. 6_suppl (February 20, 2021): 251. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.251.
Дисертації з теми "GLS1":
Hasan, Bou Issa Lama. "Étude des dépendances génomiques dans le myélome multiple surexprimant MYC." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. http://www.theses.fr/2024ULILS011.
Multiple myeloma (MM) is a hematological malignancy that accounts for around 13% of hematological cancers and is characterized by the uncontrolled proliferation of malignant plasma cells in the bone marrow. MM progresses from precursor stages, known as monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM), to the symptomatic form, MM. It is an incurable malignancy in which heterogeneity and clonal evolution allow treatment escape and disease progression. MYC alterations play an essential role in this progression. However, MYC is not therapeutically targetable due to its nuclear localization and the protein's short half-life.To overcome this, we hypothesized that the proliferative advantage induced by MYC overexpression creates genomic dependencies on other signalling pathways that become essential for cell survival. To test this hypothesis, we applied a novel approach by leveraging large-scale loss of function screen (Achilles) and 1869 small molecules screen to identify MYC-induced genomic vulnerabilities. When identified, these vulnerabilities offer an opportunity to selectively target cancer cells harbouring this overexpression and spare normal cells.Our analyses demonstrate the dependence of MYC overexpressing cells on glutamine metabolism, in particular on the GLS1 (glutaminase). We validated and functionally delineated this dependence in vitro using different approaches.Our small molecule screen highlighted that NAD synthesis inhibitors had a preferential effect on the proliferation of MYC overexpressing cells. Considering that glutamine and NAD have closely interlinked metabolic networks, we investigated the possibility of a potential synergistic effect between GLS1 and NAMPT inhibitors. We demonstrated the effectiveness of this new synergistic combination to target MYC-driven MM cells in vitro and in vivo.These results establish a solid methodological basis that can be used to develop new therapeutic approaches to address unmet therapeutic needs to target MYC in MM
Schippel-Coressel, Katja [Verfasser], and Matthias [Akademischer Betreuer] Frank. "GLP1 als Therapieoption bei Adipositas (kurz- und langwirksame GLP1 Analoga im klinischen Vergleich) / Katja Schippel-Coressel ; Betreuer: Matthias Frank." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://d-nb.info/115209534X/34.
Li, Xingnan. "Regulation of [beta]-catenin by Gli1 in epithelial transformation." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. http://www.mhsl.uab.edu/dt/2007p/li_xingnan.pdf.
Seytanoglu, Adil. "Investigation of the effects of gle1 depletion in zebrafish." Thesis, University of Sheffield, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632835.
Hutschenreuther, Antje, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, and Gerd Birkenmeier. "Modulation of GLO1 expression affects malignant properties of cells." Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-217965.
Hutschenreuther, Antje, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, and Gerd Birkenmeier. "Modulation of GLO1 expression affects malignant properties of cells." MDPI, 2016. https://ul.qucosa.de/id/qucosa%3A15256.
Lee, Jaehoon Ph D. Massachusetts Institute of Technology. "Studies of superconformal field theories using GLSM and conformal bootstrap." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/99308.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 273-288).
In this thesis, we study strongly interacting superconformal field theories in two and three dimensions. In two dimensions, we investigate N = (0, 2) gauge theories using the gauged linear sigma models (GLSM). In those theories, we identify simple mechanism by which worldsheet description of H-flux satisfying Green-Schwarz Bianchi identity arises. Under the renormalization group flow, we argue that these models flow into superconformal fixed points describing string theory compactifications backgrounds with non-trivial H-flux turned on. By analyzing quantum-consistency of effective theories with such mechanism, we identify conditions under which these theories to become interacting superconformal field theories in the infrared. In three dimensions, we study maximally supersymmetric (N = 8) conformal field theories by conformal bootstrap approach. We focus on studying the four-point function of stress-tensor multiplet. The superconformal blocks for the four-point function are computed by analyzing superconformal Ward identity. Using these blocks, we study crossing symmetry constraints both numerically and analytically. Doing so, we obtain universal bounds and exact relations of N = 8 superconformal field theory data.
by Jaehoon Lee.
Ph. D.
Mora, Saavedra Aquiles Andrés. "Plan de Marketing para un Bar GLS." Tesis, Universidad de Chile, 2010. http://www.repositorio.uchile.cl/handle/2250/102472.
Cangini, Loris. "Modern OpenGL e linguaggio GLSL per lo sviluppo di shader grafici." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
McMellon, Hannah. "Structure-function studies on putative Gly1 homologues in gram-negative bacteria." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/12921/.
Книги з теми "GLS1":
Jali. Pl*xi*gls. Bilbao: Astiberri, 2004.
Ripardo, Sérgio. Guia GLS - São Paulo. São Paulo: Publifolha, 2007.
Lindenberg, Cariê. GLS, entenda as entendidas. Rio de Janeiro: Gryphus Editora, 2005.
Ripardo, Sérgio. Guia GLS - São Paulo. São Paulo: Publifolha, 2007.
Nyarko, Philomena. Ghana living standards survey: Report on the second round (GLSS 2), October 1988-September 1989 (with corresponding tables from GLSS 1). Accra: Ghana Statistical Service, 1996.
Linton, Oliver. Small sample properties of adaptive GLS estimators. Oxford: Nuffield College, 1992.
Dohmen, Caspar. Good Bank: Das Modell der GLS Bank. Freiburg: Orange Press, 2011.
Abbud, ed. Triunfo dos pêlos e outros contos gls. São Paulo, SP: Edições GLS, 2000.
Service, Ghana Statistical. Ghana living standards survey round 6 (GLSS 6): Community facilities. Accra: Ghana Statistical Service, 2014.
Service, Ghana Statistical. Ghana living standards survey round 6 (GLSS 6): Child labour report. Accra: Ghana Statistical Service, 2014.
Частини книг з теми "GLS1":
Colubri, Andrés. "GLSL Shaders." In Processing for Android, 269–301. Berkeley, CA: Apress, 2023. http://dx.doi.org/10.1007/978-1-4842-9585-4_15.
Ala’Aldeen, Aryan, David L. Marks, Rachel L. O. Olson, and Martin E. Fernandez-Zapico. "Glioma-Associated Oncogene 1 (GLI1)." In Encyclopedia of Signaling Molecules, 2088–98. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101890.
Meyr, Herbert. "Das GLSP mit Rüstzeiten (GLSPST)." In Simultane Losgrößen- und Reihenfolgeplanung für kontinuierliche Produktionslinien, 129–58. Wiesbaden: Deutscher Universitätsverlag, 1999. http://dx.doi.org/10.1007/978-3-322-89140-2_6.
Ala’Aldeen, Aryan, David L. Marks, Rachel L. O. Olson, and Martin E. Fernandez-Zapico. "Glioma-Associated Oncogene 1 (GLI1)." In Encyclopedia of Signaling Molecules, 1–11. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4614-6438-9_101890-1.
Wee, Lionel. "Globalization." In Handbook of Pragmatics, 91–106. Amsterdam: John Benjamins Publishing Company, 2022. http://dx.doi.org/10.1075/hop.25.glo1.
Cronin, Michael. "Globalization and translation." In Handbook of Translation Studies, 134–40. Amsterdam: John Benjamins Publishing Company, 2010. http://dx.doi.org/10.1075/hts.1.glo1.
Schneeweiss, Eva. "GLS Bank: Successfully Sustainable." In Banking with Integrity, 107–14. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9780230346499_8.
Meyr, Herbert. "Das GLSP bei parallelen Linien (GLSPPL)." In Simultane Losgrößen- und Reihenfolgeplanung für kontinuierliche Produktionslinien, 159–201. Wiesbaden: Deutscher Universitätsverlag, 1999. http://dx.doi.org/10.1007/978-3-322-89140-2_7.
Schips, Bernd. "Verallgemeinerte Kleinst-Quadrate-Schätzfunktionen (GLS)." In Beiträge zur psychologischen Forschung, 135–44. Wiesbaden: Gabler Verlag, 1990. http://dx.doi.org/10.1007/978-3-322-89329-1_15.
Knottnerus, Paul. "GLS Estimation by Kalman Filtering." In Lecture Notes in Economics and Mathematical Systems, 55–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-48383-7_4.
Тези доповідей конференцій з теми "GLS1":
Henry, Christophe, Karine Berthelot, Christophe Lanneau, Cécile Orsini, Dimitri Gorge-Bernat, Isabelle Meaux, Dorine Chassin, et al. "Abstract 242: Identification of biomarkers predicting sensitivity to GLS1 inhibition using a CRISPR screen." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-242.
Suzuki, Erika, Jennifer Molina, Nakia D. Spencer, Christopher A. Bristow, Angela L. Harris, Ningping Feng, Mikhila Mahendra, et al. "Abstract 2338: The GLS1 inhibitor IPN60090 enhances antitumor immune response through metabolic reprogramming of T cells and impacts on the tumor microenvironment." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2338.
Spencer, Nakia D., Christopher A. Bristow, Virginia Giulani, Meredith A. Miller, Alessandro Carugo, Angela L. Harris, Rosalba Minelli, et al. "Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-87.
Mittal, Mukul K., and Gautam Chaudhuri. "Abstract LB-112: Increase in glutaminase (GLS1) levels through SLUG-induced repression of hsa-miR-23a in triple negative breast cancer cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-lb-112.
Scott, Gary K., Justine Rutter, Katya Frazier, Daniel Rothschild, Christina Yau, and Christopher Benz. "Abstract 5402: A new anticancer strategy based on inhibiting mitochondrial proline dehydrogenase (PRODH) and exploiting synthetic lethal interactions with p53 restoration and/or glutaminase (GLS1) inhibition." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5402.
Palant, Wladimir, Carsten Griwodz, and Pål Halvorsen. "GLS." In the 14th annual ACM international conference. New York, New York, USA: ACM Press, 2006. http://dx.doi.org/10.1145/1180639.1180818.
Chen, Feng, Chang-Tien Lu, and Arnold P. Boedihardjo. "GLS-SOD." In the 16th ACM SIGKDD international conference. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1835804.1835939.
Tornai, Robert, Ildiko Papp, and Roland Kunkli. "GLSL in batch image processing." In 2014 5th IEEE Conference on Cognitive Infocommunications (CogInfoCom). IEEE, 2014. http://dx.doi.org/10.1109/coginfocom.2014.7020407.
Gomes, Thiago, Luiz Estevao, Rodrigo de Toledo, and Paulo Roma Cavalcanti. "A Survey of GLSL Examples." In 2012 XXV SIBGRAPI Conference on Graphics, Patterns and Images Tutorials (SIBGRAPI-T). IEEE, 2012. http://dx.doi.org/10.1109/sibgrapi-t.2012.11.
Li, Sen, Zunce Wang, Yan Xu, Fengxia Lv, Yuejuan Yan, and Yujie Song. "Numerical Simulation of Compressible Flow in Gas Liquid Separator." In ASME 2010 29th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/omae2010-21039.
Звіти організацій з теми "GLS1":
Ghosal, Samit, and Binayak Sinha. The cardiovascular benefits of GLP1-RA are directly related to their positive effect on glycaemic control: A meta-regression analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0071.
Deo, Salil, David McAllister, Naveed Sattar, and Jill Pell. The time-varying cardiovascular benefits of glucagon like peptide-1 agonist (GLP-RA)therapy in patients with type 2 diabetes mellitus: A meta-analysis of multinational randomized trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2021. http://dx.doi.org/10.37766/inplasy2021.7.0097.
Qiu, Mei, Liang-Liang Ding, and Hai-Rong Zhou. Impact of SGLT2 inhibitors and GLP1 receptor agonists on respiratory infections: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2021. http://dx.doi.org/10.37766/inplasy2021.1.0092.
Qiu, Mei, Liang-Liang Ding, and Hai-Rong Zhou. Effects of SGLT2 inhibitors and GLP1 receptor agonists on risk of various arrhythmias: a meta-analysis of large randomized trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2021. http://dx.doi.org/10.37766/inplasy2021.1.0102.
Qiu, Mei, Liang-Liang Ding, and Hai-Rong Zhou. Effects of SGLT2 inhibitors and GLP1 receptor agonists on risk of various fractures: a meta-analysis of large randomized trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2021. http://dx.doi.org/10.37766/inplasy2021.1.0103.
AUGUSTONI, ARNOLD L. Laser Safety Evaluation of the Oscmar M203PI Grenade Launcher Simulator (GLS) and the Associated Umpire Control Gun. Office of Scientific and Technical Information (OSTI), June 2002. http://dx.doi.org/10.2172/801000.
Pinkus, Alan R., and Harry L. Task. Interlaboratory Study (ILS) on the Standard Test Method for Measuring Grid Line Slope (GLS) in Aerospace Transparencies. Fort Belvoir, VA: Defense Technical Information Center, May 2001. http://dx.doi.org/10.21236/ada387935.
Simakov, S. Evaluation of the Prompt Gamma-ray Spectrum from Spontaneous Fission of 252Cf. IAEA Nuclear Data Section, February 2024. http://dx.doi.org/10.61092/iaea.bz1p-e3yc.
Lui, Mortimer, and Wood. PR-273-0323-R02 Corrosion Assessment Guidance for High Strength Steels (Phase 2). Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), November 2009. http://dx.doi.org/10.55274/r0010703.
Long-term youth suicide prevention programs can have sustained effects. ACAMH, September 2019. http://dx.doi.org/10.13056/acamh.10652.