Готові списки джерел за темами / GENEPY

Добірка наукової літератури з теми "GENEPY"

Автор: Grafiati

Опубліковано: 14 березня 2023

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Статті в журналах з теми "GENEPY"

Harasimowicz, Julia. "Genezy upadków." Stan Rzeczy, no. 2(19) (November 1, 2020): 301–14. http://dx.doi.org/10.51196/srz.19.12.

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Garbol, Tomasz. "Genezy – lektury." Teksty Drugie 3 (2017): 225–37. http://dx.doi.org/10.18318/td.2017.3.13.

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Porotnikov, Igor V., Valentina P. Puykkenen, Olga Yu Antonova, and Olga P. Mitrofanova. "The efficiency of molecular markers of the <i>SKr</i> suppressor gene that determines the crossability of common wheat with rye." Ecological genetics 20, no. 3 (October 28, 2022): 203–14. http://dx.doi.org/10.17816/ecogen110867.

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BACKGROUND: Among the genes involved in the control of crossing between common wheat and rye, the dominant suppressor SKr (Suppressor of crossability) having the major effect on inhibiting crossability is the most studied. DNA-markers have been developed for this gene. There are cases of successful application of some of them in wheat breeding, but there is practically no information about their diagnostic efficiency in screening of ex situ collections. MATERIALS AND METHODS: To evaluate the effectiveness of SKr markers Xcfb341, TGlc2, gene12 и gene13 to identify forms with high crossability with rye, we studied 103 bread wheat accessions from the VIR collection with different seed set (093%) after pollinated with rye. RESULTS: Efficiency in detection crossable forms (upper 15%) was demonstrated by markers Xcfb341, TGlc2 and gene12. No significant allele-trait association was found for gene13 marker. Ten haplotypes were identified based on four markers. Five haplotypes were revealed for accessions from China, while two of them were associated with high crossability. Eleven accessions including the line L6-HSR were heterogenic in markers. For this line the relationship of diagnostic fragments with the crossability level observed in the field has been experimentally confirmed. CONCLUSIONS: The SKr gene markers studied can be used for accessions searching at ex situ collections that potentially have high crossability with rye, for controlling the retention of recessive skr alleles when regenerating seed accessions, as well as in breeding programs.

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Grésillon, Almuth. "Sceny teatralnej genezy." Wielogłos, no. 1 (39) (2019): 103–23. http://dx.doi.org/10.4467/2084395xwi.19.006.10427.

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How can we conceive of applying genetic criticism to a theatrical work, since drama is characterised by its inherent mutability and necessary incompletion? How can we analyse the genesis of a play which only becomes real on the evening of its performance? How can we defi ne the genesis documents when we know they are unstable, heterogeneous and ephemeral by defi nition? A requisite condition: the persons involved in stage direction as well as theatrical archives should be encouraged to preserve the fragile traces of the birth of a performance (logbooks, administration notebooks, rehearsal records, sketches for the sets, and so on). This study outlines a framework wherein the complex, dynamic relationship between the construction of a text and that of its performance can be exploited.

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Ashton, J., G. Cheng, I. Stafford, R. M. Beattie, and S. Ennis. "DOP64 Utilising genomics to predict outcomes and delineate novel subgroups in inflammatory bowel disease." Journal of Crohn's and Colitis 17, Supplement_1 (January 30, 2023): i137—i140. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0104.

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Abstract Background The rise of ‘big data’ in inflammatory bowel disease (IBD) presents an opportunity to improve understanding of pathogenesis and unpick the molecular complexity of this heterogenous condition. Personalisation of IBD management relies on predicting outcomes, response to therapy and prevention of complications. Here, we present results outlining subgrouping of patients and outcome prediction using multiomic/clinical data. Methods Using whole exome sequencing from 1100 patients in the Southampton IBD cohort, including 650 paediatric cases, we have performed iterative studies focused on 1) Impact of genomic variation across the NOD-signaling pathway measured by perturbation of transcription across multiple genes, 2) Development of NOD2 as a genomic biomarker of stricturing Crohn’s disease (CD), 3) Utilising machine learning and genomic data to develop disease classification models. These data utilise GenePy, a tool developed in house that summarises genomic variation to give a per individual, per gene deleteriousness metric. Results Within the NOD-signaling pathway patients harbouring deleterious variation in NOD2 had reduced NOD2 expression and increased NFKBIA expression, reflecting reduced NFKB signaling, figure 1A. We report deleterious variation in several key complexes including NOD2-RIPK2 and TAK1-TAB, resulted in reduced transcription of NFKB activators and alternative inflammatory pathway activation, figure 1C-D. Utilising genomic data we constructed a NOD2 prediction model for stricturing disease in Crohn’s disease; 56.7% of patients in the ‘high-risk group’ had stricturing behaviour, whilst in the low-risk group only 21.4% had strictures. Addition of terminal ileal (TI) disease to the NOD2 risk groups significantly improved prediction, figure 2A. Using survival modelling, high-risk group paediatric patients presenting with TI disease had a HR of 4.89 (P = 2.3×10-5) compared with the low-risk group patients without TI disease, figure 2B. Finally, we used supervised machine learning of genomic data to classify patients with CD or ulcerative colitis. We employed different gene lists and assessed how accurately we could assign patients to their diagnosis. An autoimmune gene panel produced the best model (AUROC 0.68), compared to an IBD panel (AUCROC 0.61). NOD2 was the most discriminating gene in all the gene panels. Conclusion These iterative projects demonstrate the utility of integrating genomic and clinical data to improve the subtyping of patients with IBD and provide disease prediction models. Future work will include analyses of additional inflammatory pathways and targeting different clinical outcomes. We hope clinical translation of these findings will be a step-change in precision medicine for IBD.

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Trajdos, Tadeusz M. "Wokół genezy Kazań świętokrzyskich." Z Badań nad Książką i Księgozbiorami Historycznymi 4 (September 25, 2020): 23–27. http://dx.doi.org/10.33077/uw.25448730.zbkh.2010.498.

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Czebotar, Łukasz. "Terroryzm – zarys genezy zjawiska." Biuletyn Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa Katolickiego Uniwersytetu Lubelskiego 10, no. 1 (February 23, 2023): 17–32. http://dx.doi.org/10.32084/bsawp.5023.

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The purpose of the article is to present the most important issues concerning the history of terrorism. The article contains the analysis of the four various stages (waves) of the development of terrorism (the „Anarchist Wave”, the „Anti-Colonial Wave”, the „New Left Wave”, the „Religious Wave”) and explains the formation of the modern terrorism, considered as one of the most serious global threats. Furthermore, in the text of the article, it can also be found the key findings and conclusions concerning the issues raised in it.

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Buryła, Sławomir. "Czarny potok i archiwum." Forum Poetyki 21 (December 29, 2020): 160–79. http://dx.doi.org/10.14746/fp.2020.21.26061.

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Artykuł omawia problemy genezy powieści Leopolda Buczkowskiego pt. Czarny potok. Rekonstruując skomplikowane dzieje powstania utworu, autor sięga po zachowane dokumenty genezy (publikowane i niepublikowane) zgromadzone w archiwach pisarza. Ich analiza pozwala rozwikłać niektóre problemy genezy dzieła, a także złożonej warstwy kompozycyjnej i fabularnej Czarnego potoku.

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Munévar, Gonzalo. "Postscriptum (2015)." Filozoficzne Aspekty Genezy 12 (May 24, 2021): 321–22. http://dx.doi.org/10.53763/fag.2015.12.120.

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Tekst nadesłany do Filozoficznych Aspektów Genezy. Niniejszy tekst stanowi postscriptum do artykułu Gonzalo Munévara, „Naturalistyczne wyjaśnienie wolnej woli (II)”, który ukazał się w poprzednim tomie Filozoficznych Aspektów Genezy: Gonzalo Munévar, Naturalistyczne wyjaśnienie wolnej woli (II), przeł. Radosław Plato, Filozoficzne Aspekty Genezy 2014, t. 11, s. 161-184.

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Cakswindryandani, Ni Luh Putu Ravi, Luh Putu Wrasiati, and Lutfi Suhendra. "Characteristics of “Base Genep” Extracts on Treatment Temperature and Extraction Time." Media Ilmiah Teknologi Pangan (Scientific Journal of Food Technology) 7, no. 1 (March 30, 2020): 10. http://dx.doi.org/10.24843/mitp.2020.v07.i01.p02.

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“Base Genep” is a Balinese spice that is usually served for all Balinese dishes and is usually served in a wet form. “Base Genep” or “Genep” seasoning must be used until finished because it is made from fresh ingredients that has a short shelf life. “Base Genep” is composed of turmeric, ginger, kencur, galangal, onion, garlic, pepper, coriander, candlenut, nutmeg, chili, shrimp paste, and salt. The content of bioactive compounds derived from the ingredients used makes “base genep” susceptible to oxidation processes that result in decreased quality and shelf life of base genep. This must be prevented by applying technologies such as extraction to increase the weakness of seasonings in the wet form. This study aims to know the effect of temperature and extraction time and determine the best treatment produce “base genep” extract. Extraction process using maceration method with ethanol solvent with temperature treatment and extraction time consisting of a temperature of 30ºC, 40ºC, 50ºC, 60ºC and time for 2, 3, and 4 hours. The results showed that the temperature and extraction time affected the characteristics of “base genep”. The higher the temperature and extraction time until the optimal conditions can increase yield, antioxidant activity, and total phenol extract “genep” seasoning. The results of the research showed a temperature of 50ºC for 4 hours was able to produce the characteristics of the best “genep” seasoning extract with a yield value of 25.392%, IC50 of 280.675 ppm, and a total phenol of 1177.97 mg/100 g.

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Більше джерел

Дисертації з теми "GENEPY"

Nasato, Eleonora <1991&gt. "Genere, generi e oltre." Master's Degree Thesis, Università Ca' Foscari Venezia, 2017. http://hdl.handle.net/10579/9609.

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Sesso e genere sono due dimensioni diverse, eppure legate da un rapporto reciproco. Il sesso consiste nell'aspetto biologico e fisico, caratterizzato dalla presenza di due differenti sessi cromosomici e genitali finalizzati alla riproduzione; il genere invece è dato dalla costruzione sociale e culturale dell'identità femminile e di quella maschile, applicate ai due rispettivi sessi e ritenute le uniche due possibilità identitarie naturali e legittime. In quanto elaborato socialmente e culturalmente, il genere non è fisso ma varia a seconda del periodo storico e del contesto, nonostante si cerchi di occultare questa sua origine per considerarlo piuttosto naturale ed essenziale. Maschio e femmina sono stati storicamente trasformati in uomo e donna, con le aspettative sociali, i ruoli di genere e le disuguaglianze che tale traduzione culturalmente comporta. Ciò significa che la dualità sessuale è stata spesso presa a pretesto per fondare una dicotomia di genere composta da due identità rigide, oppositive e complementari, a loro volta finalizzate all'imposizione della norma dell'eterosessualità: tale meccanismo ha prodotto e mantenuto nel tempo una disparità costante tra uomo e donna che è andata sempre a danno di quest'ultima e una discriminazione verso chi non rientra nel binarismo eterosessuale. La socializzazione è il processo sociale attraverso cui gli individui sono educati alle identità di genere ed è oggi ancora segnata da radicate stereotipie. Secondo Butler, nell'esistenza di generi e orientamenti che non sono conformi alla norma eterosessista è possibile scorgere la possibilità di sovversione di tale sistema, che è performativo e proprio per questo può essere decostruito e continuamente rielaborato per una maggiore democratizzazione.

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Melo, Marcia Helena de. "A apropriação de um genero : um olhar para a genese de texto no Ensino Medio." [s.n.], 2000. http://repositorio.unicamp.br/jspui/handle/REPOSIP/269619.

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Orientador: Raquel Salek Fiad
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
Made available in DSpace on 2018-07-28T05:52:35Z (GMT). No. of bitstreams: 1 Melo_MarciaHelenade_M.pdf: 5433291 bytes, checksum: 3a7265f53f7d781d34df2aaf6268349a (MD5) Previous issue date: 2000
Resumo: A reflexão aqui empreendida procura olhar para a produção escrita como resultado de um processo de construção, operado em uma dimensão que inclui esboços, plano da obra, elaboração, até chegar às correções finais. Acreditamos que uma das maneiras de que o lingüista pode dispor para entender o processo de escrita seja através de índices, pistas, deixados no texto, como os processos de apagamentos, substituições, acréscimos, novas ordenações, pausas etc. São pistas privilegiadas para a compreensão das hipóteses que o escrevente formula sobre o texto e da relação que mantém com ele e com o discurso que o envolve. Estas pistas de produção de escrita, portanto, podem nos ajudar a compreender melhor a relação entre o sujeito e a linguagem. Buscamos, na Critica Genética, os elementos que nos permitiram fazer algumas escolhas de natureza conceitual e metodológica. Com uma reconhecida experiência e tradição de tratamento dos manuscritos essencialmente literários, esta área do conhecimento é a que melhor conseguiu operacionalizar métodos de investigação de rascunhos e melhor compreender o estatuto das rasuras, no caso dos manuscritos de grandes escritores da literatura mundial. A noção de texto, a partir do aparecimento da Crítica Genética, sofre uma reviravolta. Sua realidade mais profunda não se encontra mais no produto (acabado, pronto, definido, separado do prototexto e do pós-texto, como pensava a teoria estruturalista); mas na sua produtividade, no "sem-fim de operações possíveis". No entanto, a maioria dos meios de que dispõe o geneticista para classificar os rascunhos ou para interpretar as microtransformações escriturais têm sido emprestados quase diretamente do arsenal conceptual da Lingüística. Evidentemente, quando os geneticistas se referem à busca de subsídios teórico-metodológicos na Lingüística, fazem questão de apontar a especificidade do tipo de modalidade de linguagem que está em jogo: a escrita, com todas as conseqüências da constituição de uma situação em que os elementos da enunciação não estão co-presentes no texto (Grésillon & Lebrave, 1982:134). Nosso interesse, não obstante, pauta-se sobre os processos de construção de textos produzidos em ambiente escolar. Duas adolescentes do Ensino Médio de uma escola comunitária-particular da cidade de Valinhos elaboram um texto, conjuntamente, a fim de que pudéssemos analisar como se deu a apropriação de um determinado gênero do discurso. Mais especificamente, pretendemos analisar de que forma as alunas em questão, sob determinadas condições de produção, mostraram ter se apropriado do gênero notícia. Buscamos, ainda, apreender o que esses sujeitos demonstraram conhecer sobre tal gênero e como a construção social desse gênero apareceu na escrita e fala deles. Também foi nosso objetivo apreender o que expressaram sobre a configuração textual do gênero e quais recursos lingüísticos utilizaram para realizarem o gênero. Para captarmos a linguagem em seu status nascendi, fizemos uso de um software francês chamado Genèse, desenvolvido pela Association Française pour Ia Lecture, em 1993, com objetivos pedagógicos. Com ele pudemos acompanhar todo o processo de produção desse texto. Suas idas e vindas, suas substituições, novas ordenações, pausas, acréscimos etc. puderam ser registrados em forma de relatórios impressos com a presença das modificações operadas no texto. Além do software Genèse, todo o momento de elaboração do texto foi filmado em fita de vídeo, com o objetivo de capturarmos o diálogo mantido entre os sujeitos a respeito do texto: suas reflexões, suas dúvidas etc. Seguiu-se, ainda, uma entrevista com as próprias alunas, desta vez gravada em fita de áudio, questionando os motivos que as levaram a apagar, substituir, adicionar, a trazer determinado elemento lingüístico etc. Tal trabalho requer uma linha teórica que responda à reflexão que se pretende empreender: a gênese de um texto escolar. No que se refere à concepção de linguagem, vemo- Ia como "trabalho/atividade constitutivo da subjetividade/alteridade e da própria linguagem, que pode ser tomada como um objeto sobre o qual se pode refletir e falar" (Franchi, 1992). Em relação à questão dos gêneros do discurso, usamos a abordagem sócio-interacionista de Bakhtin [1952-3] (1997)
Abstract: Not informed.
Mestrado
Ensino-Aprendizagem de Lingua Materna
Mestre em Linguística Aplicada

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Schiel, Ralph J. "Genera." [S.l. : s.n.], 2003. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB10952966.

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ARENA, GIULIA. "Il bilancio di genere nelle università italiane. Come il genere viene costruito attraverso le policy di genere." Doctoral thesis, Università degli studi di Genova, 2022. http://hdl.handle.net/11567/1095933.

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This research stems from the necessity to critically understand a phenomenon "new" as gender budgeting, especially in the Italian university context. Gender budgeting is a tool that is traced back to the framework of gender mainstreaming and consists of a contextual and financial analysis of the different impact that political decisions have on men and women, starting from the assumption that there are no truly neutral decisions. The purpose of the research is to approach gender budgeting from a critical and feminist perspective and not merely a descriptive one, with the aim of investigating the theoretical frameworks used in implementing gender budgets. The main question that has guided the present research is how gender budgeting relates to the gender inequalities already present in academia and how it transforms the idea of gender equality that is promulgated by the university institution. The project's main contribution lies precisely in having applied to the case of university and Italian gender budgets a critical methodology, the so-called Critical Frame Analysis, which until now had only been used to analyze broader phenomena such as gender mainstreaming. The goal was to understand how the "gender budget" tool has taken on its own characteristics in the Italian academic context and what kind of gender narratives can be found in these documents. Four main theoretical frameworks that can serve as the informational basis for gender budgets were traced, thus debunking the idea that this type of tool can be attributed solely to the approach of gender mainstreaming. In conclusion, with the present work, an attempt was made to break down the gender budget into its constituent elements, in order to analyze to what kind of theoretical framework it was possible to relate each element, always taking into consideration how gender budgeting has been and is concretely implemented in the context of Italian universities, finally using the concrete experience of gender budgeting at the University of Genoa as a case study to analyze some of the phenomena that emerged in the course of this research.

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Santin, Dionete Aparecida 1957. "Revisão taxomica do genero Astronium Jacq. revalidação do genero Myracrodruon Fr. (Anacardiaceae)." [s.n.], 1989. http://repositorio.unicamp.br/jspui/handle/REPOSIP/315107.

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Orientador : Hermogenes de Freitas Leitão Filho
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-07-15T06:14:23Z (GMT). No. of bitstreams: 1 Santin_DioneteAparecida_M.pdf: 13411820 bytes, checksum: 82cabc08ff58d615c1912fe5f47edb36 (MD5) Previous issue date: 1989
Resumo: Este trabalho consiste de uma revisão taxonômica do gênero Astronium Jacquin (Anacardiaceae). Foi baseado fundamentalmemte num estudo minucioso das características morfológicas das espécies e em muitas observações de campo, que permitiram a determinação do número de espécies e identificação das mesmas. O gênero Astronium é exclusivamente neotropical. Sendo constituído por 8 espécies, das quais 7 ocorrem no Brasil. Com base na forma dos frutos, tamanho e forma das sépalas nas flores e frutos, as espécies ficaram divididas entre 2 subgêneros: Macrocalix, com 1 espécie A. concinnum e Astronium, com 7 espécies: A. graveolens, A. fraxinifolium, A. ulei, A. lecointei, A. glaziovii, A. obliquum e A. nelson-rosae. Foi reconhecida uma espécie nova, A. nelson-rosae; uma espécie foi excluida, A. gardneri e algumas foram sinonimizadas. Myracrodruon foi considerado um gênero independente e de Astronium e revalidado, baseando-se em caracteres de placentação .. e tipo de frutos, e ficou constituído por 2 espécies: M. balansae e M. urundeuva. Supõe-se que o Brasil é o centro de origem e diversidade do gênero Astronium e o centro de origem de M. urundeuva. Pelo menos 4 espécies têm sua origem aqui no Brasil A. concinnum,A. glaziovii, A.nelson-rosae e M. urundeuva. E bem possível a existência de híbridos de A. graveolens e A. fraxinifolium em áreas de transição entre cerrados (savanas) e matas
Abstract: The present study consists of a taxonomic revision of the genus Astronium Jacq. (Anacardiaceae) . It was essentially based on a detailled study of morphological characters and field observation. The genus Astronium is exclusively neotropical, comprising 8 species, 7 of them native in Brasil. Based on fruit shape and size and shape of sepals of flowers and fruits the genus was segregated into two subgenus: Macrocalyx wich a single specie A. concinnum and Astronium including 7 species A. graveolens, A. fraxinifolium, A. obliquum, A. ulei, A. nelson-rosae, A. lecointei A. glaziovii. A new specie A. nelson-rosae was described and another A. gardneri was excluded, some species it was synonymized. Taking into account the placentation and fruit type, Myracrodruon was revalidated and considered distint from Astronium. This genus comprises two species: M. balansae and M. urundeuva. Brazil is the center of origin and diversity of the genus Astronium and the center of origin of M. urundeuva. At least 4 species have theirs origin in Brazil : A. concinnum, A. glaziovii, A. nelson-rosae and M. urundeuva. Its possible the ocurrence of hibrids betweem A. graveolens and A. fraxinifolium in areas of transition from cerrado to forest
Mestrado
Mestre em Ciências Biológicas

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坂部, 俊樹, 正彦酒井, 圭一朗草刈, and 直樹西田. "Program Generation System : GeneSys." INTELLIGENT MEDIA INTEGRATION NAGOYA UNIVERSITY / COE, 2005. http://hdl.handle.net/2237/10379.

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Žiliuk, Jaroslav. "Lietuvos aukštojo mokslo genezė." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130808_122123-04755.

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Darbo tema: Lietuvos aukštojo mokslo genezė. Šio darbo tikslas - ištirti Lietuvos aukštojo mokslo genezę, siekiant nustatyti esminius aukštųjų mokyklų struktūrinius, vadybinius, finansinius pokyčius atkūrus Lietuvos nepriklausomybę. Pirmoje darbo dalyje atlikta mokslinės literatūros analizė. Šioje dalyje analizuojama kokias vietas Lietuvos švietime užima kolegijos ir universitetai, pateikiama aukštojo mokslo raida, apžvelgiamas aukštųjų mokyklų finansavimas ir valdymas. Antroje dalyje pateikiama statistinė informacija. Analizuojami rodiklių pokyčiai. Empirinėje dalyje, anketinės apklausos metodu atliktas tyrimas. Tyrimo tikslas - ištirti respondentų nuomones siekiant nustatyti esminius ir dabartinius aukštųjų mokyklų bruožus. Respondentų nuomonės padeda nustatyti aukštojo mokslo genezė ir pokyčius. Apklausoje dalyvavo 313 respondentai.
Work theme: Higher education genesis in Lithuania. The goal is to explore the genesis of the Lithuanian higher education in order to identify the most critical high-school structural, managerial, financial developments in the restoration of Lithuania's independence. In the first part of the work is the scientific literature analyze. This section analyzes Lithuanian Education, the development of higher education, an overview of higher education financing and management. The second section presents statistical information. Analyzing indicators. The empirical part is the questionnaire survey method. The aim is to explore respondents' opinions in order to identify the most critical and current high school characteristics. Respondents' opinion helps to determine the genesis of higher education and change. The survey involved 313 respondents.

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McTague, Carl. "Generalizations of elliptic genera." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608783.

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Nunes, Junior Vilardes. "Poliacetilenos do genero Pterocaulon." [s.n.], 1988. http://repositorio.unicamp.br/jspui/handle/REPOSIP/250174.

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Orientador : Eva Gonçalves Magalhães
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Quimica
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Brito, Beteizabete de. "Genese de "a herança"." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270786.

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Orientador: Ingedore Grunfeld Villaça Koch
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
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Resumo: Neste trabalho, estudei a gênese dos poemas de «A Herança", de Zila Mamede, buscando compreender como se estabelece o processo escritural, através dos acréscimos, das supressões e das substituições contidos nos manuscritos autógrafos. Perseguindo os traços redacionais, tentei perceber o texto poético se inventando, se revelando, paradigmaticamente se compondo, até finalmente se fixar sob a forma estável, como texto definitivo, dado a público. Além dos vestígios pontuais de fixação do discurso interior, procurei encontrar nexos nas instâncias da escritura entre herói e autor e observar a linguagem se constituindo no processo criador. O suporte teórico para realização deste trabalho procede da Genética Textual, da Lingüística, bem como da Teoria Literária
Abstract: In this thesis I study the genesis ai the poems fiam " A Herança" by Zila Mamede, attempting to understand how the writing process is built through addings, suppressions and substitutions detected in manuscrips. In so doing I tried to perceive how the poetic text is reivented, revealing itself as a paradigm that is being built until it finally fits into a stable form, as a definite text given to the public. Besides the signs of the interior discourse, I attempted to find links between hero and author and the creative process of language. The theorethical basis I use comes from Textual Genetic, Linguistics and Literary Theory
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Doutor em Linguística

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Книги з теми "GENEPY"

Guglielminetti, Marziano. Sulla novella italiana: Genesi e generi. Lecce: Milella, 1990.

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Gorski, Grzegorz. Wokol genezy PRL. Lublin: Wydawnictwo Katolickiego Uniwersytetu Lubelskiego, 2004.

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Górski, Grzegorz. Wokół genezy PRL. 2nd ed. Lublin: Wydawn. KUL, 2004.

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Górski, Grzegorz. Wokół genezy PRL. Lublin: Wydawn. KUL, 2000.

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Leccardi, Carmen. Tra i generi: Rileggendo le differenze di genere, di generazione, di orientamento sessuale. Milano: Guerini e associati, 2002.

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Generi della memoria e memoria di genere: Primo Levi, Ruth Klüger e la Shoah. Acireale]: Bonanno editore, 2014.

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Matłachowski, Jan. Kulisy genezy powstania warszawskiego. 2nd ed. Warszawa: Wydawn. Ojczyzna, 1994.

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Gene structure and expression. Cambridge [Cambridgeshire]: Cambridge University Press, 1985.

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Gene structure and expression. 2nd ed. Cambridge [England]: Cambridge University Press, 1991.

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Gene structure and expression. 3rd ed. Cambridge: Cambridge University Press, 1996.

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Частини книг з теми "GENEPY"

von Alemann, Ulrich. "Genese." In Organisierte Interessen in der Bundesrepublik, 145–58. Wiesbaden: VS Verlag für Sozialwissenschaften, 1987. http://dx.doi.org/10.1007/978-3-322-86026-2_8.

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Paek, Kee-Yoeup, and Hosakatte Niranjana Murthy. "Genera." In Orchid Biology: Reviews and Perspectives, VIII, 235–86. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-017-2500-2_5.

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von Alemann, Ulrich. "Genese." In Organisierte Interessen in der Bundesrepublik Deutschland, 145–58. Wiesbaden: VS Verlag für Sozialwissenschaften, 1989. http://dx.doi.org/10.1007/978-3-322-97216-3_8.

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Cable, James. "Geneva." In The Geneva Conference of 1954 on Indochina, 66–71. London: Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1057/9780230599253_6.

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Ayliffe, Michael, Ming Luo, Justin Faris, and Evans Lagudah. "Disease Resistance." In Wheat Improvement, 341–60. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-90673-3_19.

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AbstractWheat plants are infected by diverse pathogens of economic significance. They include biotrophic pathogens like mildews and rusts that require living plant cells to proliferate. By contrast necrotrophic pathogens that cause diseases such as tan spot, Septoria nodurum blotch and spot blotch require dead or dying cells to acquire nutrients. Pioneering studies in the flax plant-flax rust pathosystem led to the ‘gene-for-gene’ hypothesis which posits that a resistance gene product in the host plant recognizes a corresponding pathogen gene product, resulting in disease resistance. In contrast, necrotrophic wheat pathosystems have an ‘inverse gene-for-gene’ system whereby recognition of a necrotrophic fungal product by a dominant host gene product causes disease susceptibility, and the lack of recognition of this pathogen molecule leads to resistance. More than 300 resistance/susceptibility genes have been identified genetically in wheat and of those cloned the majority encode nucleotide binding, leucine rich repeat immune receptors. Other resistance gene types are also present in wheat, in particular adult plant resistance genes. Advances in mutational genomics and the wheat pan-genome are accelerating causative disease resistance/susceptibility gene discovery. This has enabled multiple disease resistance genes to be engineered as a transgenic gene stack for developing more durable disease resistance in wheat.

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Molesini, Barbara, and Tiziana Pandolfini. "Exogenous application of RNAs as a silencing tool for discovering gene function." In RNAi for plant improvement and protection, 14–24. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0003.

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Abstract This chapter focuses on the importance of the RNA silencing technique in unraveling the function of genes by inhibiting gene expression at the post-transcriptional level, and is particularly appropriate for studying developmental processes such as fruit setting and growth that require a tight organ/tissue and time-specific regulation of the expression of target genes. Some methods used for establishing the function of a specific gene altering gene expression at either the genomic or post-transcriptional level are also presented.

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Safran, Marilyn, Naomi Rosen, Michal Twik, Ruth BarShir, Tsippi Iny Stein, Dvir Dahary, Simon Fishilevich, and Doron Lancet. "The GeneCards Suite." In Practical Guide to Life Science Databases, 27–56. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-5812-9_2.

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AbstractThe GeneCards® database of human genes was launched in 1997 and has expanded since then to encompass gene-centric, disease-centric, and pathway-centric entities and relationships within the GeneCards Suite, effectively navigating the universe of human biological data—genes, proteins, cells, regulatory elements, biological pathways, and diseases—and the connections among them. The knowledgebase amalgamates information from >150 selected sources related to genes, proteins, ncRNAs, regulatory elements, chemical compounds, drugs, splice variants, SNPs, signaling molecules, differentiation protocols, biological pathways, stem cells, genetic tests, clinical trials, diseases, publications, and more and empowers the suite’s Next Generation Sequencing (NGS), gene set, shared descriptors, and batch query analysis tools.

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Lemmin, Ulrich, Brian V. Timms, Jónas Elíasson, Yerubandi R. Rao, Reginald W. Herschy, and Reginald W. Herschy. "Geneva Lake." In Encyclopedia of Lakes and Reservoirs, 287–90. Dordrecht: Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-1-4020-4410-6_84.

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Horak, Ivan G., Heloise Heyne, Roy Williams, G. James Gallivan, Arthur M. Spickett, J. Dürr Bezuidenhout, and Agustín Estrada-Peña. "Other Genera." In The Ixodid Ticks (Acari: Ixodidae) of Southern Africa, 511–40. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-70642-9_9.

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Тези доповідей конференцій з теми "GENEPY"

Neitz, Jay, Maureen Neitz, and Gerald H. Jacobs. "More than three cone types in normal color vision?" In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.fm6.

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Normal human color vision is usually thought to be based on only three spectrally different cone types. However, two facts suggest the possibility that some color-normal males could have more than three cone pigment types: (1) Most people with normal color vision have more than two photopigment genes on each X-chromosome and (2) there appear to be genetically specified variations in spectral positions of the normal middle-wavelength-sensitive (MWS) and long-wavelength-sensitive (LWS) pigments. For example, a male might have one gene encoding an LWS pigment and two genes encoding slightly different MWS pigments. If all three different X-encoded genes were expressed in different cones, then this person would have four spectrally different cone types. How firm is the assumption that more than two of the X-encoded pigment genes can be expressed? Both analysis of the statistics of photopigment gene number among different color vision phenotypes and analysis of the arrangement of pigment genes on the X-chromosome yield insight into this aspect of photopigment gene expression. These analyses suggest that individuals with multiple pigment genes on the X-chromosome may express more than two of those genes.

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Marco, Anderson, Mario Gazziro, and David Martins Jr. "High performance computing architectures analysis for gene networks inference." In XX Simpósio em Sistemas Computacionais de Alto Desempenho. Sociedade Brasileira de Computação, 2019. http://dx.doi.org/10.5753/wscad.2019.8656.

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Modeling and inference of biological systems are an important field in computer science, presenting strong interdisciplinary aspects. In this context, the inference of gene regulatory networks and the analysis of their dynamics generated by their transition functions are important issues that demand substantial computational power. Because the algorithms that return the optimal solution have an exponential time cost, such algorithms only work for gene networks with only dozens of genes. However realistic gene networks present hundreds to thousands of genes, with some genes being hubs, i.e., their number of predictor genes are usually much higher than average. Therefore there is a need to develop ways to speed up the gene networks inference. This paper presents a benchmark involving GPUs and FPGAs to infer gene networks, analysing processing time, hardware cost acquisition, energy consumption and programming complexity. Overall Titan XP GPU achieved the best performance, but with a large cost regarding acquisition price when compared to R9 Nano GPU and DE1-SOC FPGA. In its turn, R9 Nano GPU presented the best cost-benefit regarding performance, acquisition price, energy consumption, and programming complexity, although DE1-SOC FPGA presented much smaller energy consumption.

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Neitz, Maureen. "Molecular genetics of red-green color vision." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.fm2.

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Genes encoding cone pigments sensitive to middle-to-long wavelengths lie in a head-to-tail tandem array on the X-chromosome. Although two X-encoded genes, one for long-wavelength-sensitive pigments and one for middle-wavelength-sensitive pigments, are sufficient to serve trichromatic color vision, most people have more than two such genes. The arrangement, location, and degree of homology of the pigment genes promote recombination within the tandem arrays. Such recombination events produce pigment-gene complements that differ in the number and sequences of individual genes and in the interrelationships between genes. The accumulation of recombination-generated changes over the span of evolutionary time has culminated in a large number of X-encoded photopigment gene complements in the human population. It is, thus, not surprising that there are widespread variations in human color vision.

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Da Silva, Carla Fernandes, Kuruvilla Joseph Abraham, and Evandro Eduardo Seron Ruiz. "Correlacionando genes e doenças através de caminhos metabólicos." In XVII Simpósio Brasileiro de Computação Aplicada à Saúde. Sociedade Brasileira de Computação - SBC, 2017. http://dx.doi.org/10.5753/sbcas.2017.3725.

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Um dos principais desafios da ciência é identificar os fatores que causam essas doenças, dentre estes fatores estão os genes. Neste trabalho, será apresentada uma metodologia para priorizar genes e vias metabólicas relacionados a uma doença complexa, com o desafio de descobrir quais os genes podem contribuir para desencadear uma doença complexa. O objetivo é desenvolver uma metodologia para predição de gene-doença através da integração de dados de genes-doencas-vias metabólicas, visando a descoberta de novos genes associado a doença.

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Goveia, Rebeca Mota, Paula Francinete Faustino Silva, Thais Bomfim Teixeira, Isabela Gasparini Arraes, Ruffo Freitas-Júnior, and Elisângela Paula Silveira Lacerda. "ANALYSIS OF PATHOGENIC AND UNCERTAIN SIGNIFICANCE VARIANTS IN NINE GENES OF THE BRCA1-MEDIATED HOMOLOGOUS RECOMBINATION PATHWAY IN PATIENTS WITH SUSPECTED HEREDITARY BREAST AND OVARIAN CANCER SYNDROME IN CENTRAL BRAZIL." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1038.

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Introduction: Breast cancer is the most frequent type of cancer in the world and the biggest cause of female deaths. About 10%–15% of cases are due to hereditary factors. The profile of genetic variants is still scarcely known among the Brazilian population and there are no published data for the central region of the country. Objectives: This study aimed to analyze the profile of pathogenic variants (PV) and of the ones of uncertain significance (VUS) for the RAD50, RAD51C, RAD51D, ATM, PALB2, BRIP1, BARD1 and CHEK2 genes in this population. Methods: 113 patients diagnosed with breast or ovarian cancer who met the National Comprehensive Cancer Networking criteria for hereditary breast and ovarian cancer syndrome were selected. The genes had all regions sequenced using NGS (New Generation Sequencing) and the raw data were evaluated using the Sophia DDM and IonReporter softwares. Results: A total of 3.53% of patients had PV in the PALB2 (c.2257C>T), BARD1 (c.176_177delAG), RAD50 (c.2165dupA) or ATM (c.7913G>A) genes. Patients with pathogenic variants in ATM and PALB2 genes were diagnosed before the age of 40. Patients with pathogenic variants in the BARD1 and RAD50 genes had triple negative breast cancer before the age of 60. The patient with a pathogenic variant in the RAD50 gene also developed ovarian cancer. It was observed that 24.77% of the patients had some VUS, 35.29% of which were in the ATM gene, and a new VUS in the CHEK2 gene (c.1151T>C), related to male breast cancer. Conclusions: These findings contribute to a better understanding of the phenotype of patients with pathogenic variants related to breast cancer in non-BRCA genes. In addition, it reveals a new pathogenic variant in the CHEK2 gene, not described in the literature, related to a case of male breast cancer.

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Li, Ling. "CRISPR/Cas9-based editing of OsNF-YC4/GmNF-YC4 promoter yields high-protein crops." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/qsgt8379.

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Genome editing is a new breeding technology widely touted for transgene-free crop improvement; however, to date, the majority of derived traits are created through gene knockout. We describe a novel approach using gene editing to upregulate gene expression by removing negative repressor binding motifs. Our previous work demonstrated that ectopic expression of NF-YC4 increases protein content of leaves and seeds at the expense of carbohydrates. We detected several conserved motifs predicted to be bound by repressors in the promoter of rice and soybean NF-YC4 genes. Using CRISPR/Cas9 to edit the promoters of rice and soybean NF-YC4 genes, we deleted promoter fragments harboring repressor binding motifs. Those deletions resulted in decreased repressor binding, increased NF-YC4 expression, increased protein and decreased carbohydrates. Gene-edited plants showed up to 48% higher leaf protein and 15% increased seed protein. Moreover, we exemplify a general approach for upregulating gene expression through targeted genomic deletions.

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Huber, P., J. Dalmon, M. Laurent, G. Courtois, D. Thevenon та G. Marguerie. "CHARACTERIZATION OFTHE 5’FLANKING REGION FOR THE HUMAN FIBRINOGEN β GENE". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642889.

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Fibrinogen is coded by three separate genes located in a 50kb region of chromosome 4 and organized in a α - β - γ orientation with an inversion of the gene 3- A human genomic library was constructed using the EMBL4 phage and screened with cDNA probes coding for human fibrinogen Aα, Bβ and γ chains. Clones, covering the fibrinogen locus,were identified, and their organization was analyzed by means of hybridization and restriction mapping. Among these clones one recombinant phage containing the β gene and large 5’ and 3’ -flanking sequences was isolated.To identify the regulatory sequences Dpstream from the human β gene, a 1.5 kb fragment of the immediate 5’-flanking region was sequenced. The SI mapping experiments revealed three transcription initiation sites. PotentialTATA and CAAT sequences were identified upstream the initiation start points at the positions -21 and -58 from the first initiation start point.Comparison of this sequence with that previously reported for the same region upstream from the human γ gene revealed no significant homology which suggests that the potential promoting sequences of these genes are different. In contrast, comparison of the 5’flanking regions of human and rat β genes showed more than 80% homology for 142 bp upstream from the gene. This highly conserved region is a potential candidate for a regulatory sequence of the human β gene.To verify this activity, a β fibrinogen minigene was constructed by deletion of the internal part of the normal gene and including 3.4kb of the 5’flanking region and 1.4kb of the 3’flanking region. The minigene was transfected into HepG2, a human hepatoma cell line, to show whether the 5’flanking region of the human fibrinogen gene contains DNA sequences sufficient for efficient transcription in HepG2. Constructions of several parts of the sequenced 5’flanking region of the human β gene with the gene of the chloramphenical acetyl transferase have been also transfected in the HepG2 cells to determine the specificity of the gene expression and to localize the sequences controlling the transcription of the gene.

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Danilova, Natalia, Kamalya Karamova, and Polina Galitskaya. "BIOCHAR ENHANCES ANTIBIOTIC-RESISTANT GENES REMOVAL FROM AQUEOUS ECOSYSTEMS." In 22nd SGEM International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022/5.1/s20.008.

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Pollution of aquatic ecosystems with antibiotic-resistant genes originating from human medicine and veterinary is an urgent problem due to the potential threaten to public health. Antibiotic-resistant genes enter surface waters and wastewater through vertical and horizontal water runoff. At the same time, heavy metals and biogenic substances often presented in aqueous ecosystems often exacerbate the problem since the drive the horizontal transfer of antibiotic-resistance genes. To solve the problem of purification of waters from antibiotic-resistant genes, the adsorbing agents, such as biochar, might be used. In this work, we studied the effect of biochar on the dynamics of the content of tetracycline-resistant genes in a liquid LB medium with a microbial community transferred to the medium from compost. The following additives were used - Cu (600 �g*l-1), Cd (130 �g*l-1), Ni (70 �g*l-1), Fe (1500 �g*l-1), humic acids (6%), oxytetracycline (300 mg/l). Real-time PCR revealed the absence of the tet(O) gene both in all variants with and without biochar. The highest excesses over control were found for the tet(M) and tet(C) genes. The introduction of biochar made it possible to reduce the content of antibiotic-resistant genes in all samples with different additives. Thus, in the variant with Cd, the content of the tet(A), tet(B), tet(C) � tet(S) gene was eliminated. The tet(�), tet(E) � tet(S) genes were completely absent in the sample with antibiotic.

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Rao, Jiahua, Shuangjia Zheng, Sijie Mai, and Yuedong Yang. "Communicative Subgraph Representation Learning for Multi-Relational Inductive Drug-Gene Interaction Prediction." In Thirty-First International Joint Conference on Artificial Intelligence {IJCAI-22}. California: International Joint Conferences on Artificial Intelligence Organization, 2022. http://dx.doi.org/10.24963/ijcai.2022/544.

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Illuminating the interconnections between drugs and genes is an important topic in drug development and precision medicine. Currently, computational predictions of drug-gene interactions mainly focus on the binding interactions without considering other relation types like agonist, antagonist, etc. In addition, existing methods either heavily rely on high-quality domain features or are intrinsically transductive, which limits the capacity of models to generalize to drugs/genes that lack external information or are unseen during the training process. To address these problems, we propose a novel Communicative Subgraph representation learning for Multi-relational Inductive drug-Gene interactions prediction (CoSMIG), where the predictions of drug-gene relations are made through subgraph patterns, and thus are naturally inductive for unseen drugs/genes without retraining or utilizing external domain features. Moreover, the model strengthened the relations on the drug-gene graph through a communicative message passing mechanism. To evaluate our method, we compiled two new benchmark datasets from DrugBank and DGIdb. The comprehensive experiments on the two datasets showed that our method outperformed state-of-the-art baselines in the transductive scenarios and achieved superior performance in the inductive ones. Further experimental analysis including LINCS experimental validation and literature verification also demonstrated the value of our model.

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Cool, D. E., and R. T. A. MacGillivray. "CHARACTERIZATION OF THe HUMAN FACTOR XII GENE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642800.

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Surface activation of the plasma systems involved with coagulation, fibrinolysis, renin formation and kinin generation involves factor XII (Hageman factor). This protein is a 76,000 dalton glycoprotein which circulates in plasma as an inactive form of a serine protease. A human liver cDNA coding for factor XII was used to screen a human genomic phage library. Two overlapping clones were isolated, XHXII27 and XHXII76, and contain the entire gene for human factor XII. The gene is 13.5 Kbp in length and consists of 14 exons and 13 introns. The transcriptional start site of the mRNA was determined using S1 mapping and primer extension analysis. The results indicate that the 5′ untranslated end of the mRNA has a leader sequence of 47 bp and is not interrupted by an intron in the gene. DNA sequence analysis of the region upstream of the transcriptional start site does not contain TATA or CAAT sequences, which are often found in other genes transcribed by RNA polymerase II. The positions of the introns in the coding sequence separate the protein into domains which are homologous to similar regions found in fibronectin and tissue-type plasminogen activator. Furthermore, wherever protein homologies are found, the positions of the introns in the triplet codon occur in the same reading frame as in the tissue-type plasminogen activator, urokinase plasminogen activator and factor XII genes. The intron/exon organization of the factor XII gene is different to the organization of other coagulation genes such as prothrombin, factor IX and factor X. Therefore, factor XII appears to have evolved as a member of the plasminogen activator family of genes rather than as a member of the clotting factor gene family.

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Звіти організацій з теми "GENEPY"

MacInnes, M., M. R. Altherr, D. Ludwig, R. Pedersen, and C. Mold. The biology of novel animal genes: Mouse APEX gene knockout. Office of Scientific and Technical Information (OSTI), July 1997. http://dx.doi.org/10.2172/505320.

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Grant, S. R. Characterization of Arabidopsis Genes Involved in Gene Silencing. Final Progress Report. Office of Scientific and Technical Information (OSTI), February 1999. http://dx.doi.org/10.2172/825155.

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Palukaitis, Peter, Amit Gal-On, Milton Zaitlin, and Victor Gaba. Virus Synergy in Transgenic Plants. United States Department of Agriculture, March 2000. http://dx.doi.org/10.32747/2000.7573074.bard.

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Transgenic plants expressing viral genes offer novel means of engendering resistance to those viruses. However, some viruses interact synergistically with other viruses and it is now known that transgenic plants expressing particular genes of one virus may also mediate synergy with a second virus. Thus, our specific objectives were to (1) determine if transgenic plants resistant to one virus showed synergy with another virus; (2) determine what viral sequences were essential for synergy; and (3) determine whether one of more mechanisms were involved i synergy. This project would also enable an evaluation of the risks of synergism associated with the use of such transgenic plants. The conclusion deriving from this project are as follows: - There is more than one mechanism of synergy. - The CMV 2b gene is required for synergistic interactions. - Synergy between a potyvirus and CMV can break natural resistance limiting CMV movement. - Synergy operates at two levels - increase in virus accumulation and increase in pathology - independently of each other. - Various sequences of CMV can interact with the host to alter pathogenicity and affect virus accumulation. - The effect of synergy on CMV satellite RNA accumulatio varies in different systems. - The HC-Pro gene may only function in host plant species to induce synergy. - The HC-Pro is a host range determinant of potyviruses. - Transgenic plants expressing some viral sequences showed synergy with one or more viruses. Transgenic plants expressing CMV RNA 1, PVY NIb and the TMV 30K gene all showed synergy with at least one unrelated virus. - Transgenic plants expressing some viral sequences showed interference with the infection of unrelated viruses. Transgenic plants expressing the TMV 30K, 54K and 126K genes, the PVY NIb gene, or the CMV 3a gene all showed some level of interference with the accumulation (and in some cases the pathology) of unrelated viruses. From our observations, there are agricultural implications to the above conclusions. It is apparent that before they are released commercially, transgenic plants expressing viral sequences for resistance to one virus need to be evaluated fro two properties: - Synergism to unrelated viruses that infect the same plant. Most of these evaluations can be made in the greenhouse, and many can be predicted from the known literature of viruses known to interact with each other. In other cases, where transgenic plants are being generated from new plant species, the main corresponding viruses from the same known interacting genera (e.g., potexviruses and cucumoviruses, potyviruses and cucumoviruses, tobamoviruses and potexviruses, etc.) should be evaluated. - Inhibition or enhancement of other resistance genes. Although it is unlikely that plants to be released would be transformed with HC-Pro or 2b genes, there may be other viral genes that can affect the expression of plant genes encoding resistance to other pathogens. Therefore, transgenic plants expressing viral genes to engender pathogen-derived resistance should be evaluated against a spectrum of other pathogens, to determine whether those resistance activities are still present, have been lost, or have been enhanced!

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Lifschitz, Eliezer, and Elliot Meyerowitz. The Relations between Cell Division and Cell Type Specification in Floral and Vegetative Meristems of Tomato and Arabidopsis. United States Department of Agriculture, February 1996. http://dx.doi.org/10.32747/1996.7613032.bard.

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Meristems were the central issue of our project. Genes that are required for cell division, cell elongation, cell proliferation and cell fate were studied in the tomato system. The analysis of the dUTPase and threonine deaminase genes, along with the dissection of their regulatory regions is completed, while that of the RNR2 and PPO genes is at an advanced stage. All these genes were isolated in our laboratory. In addition, 8 different MADS box genes were studied in transgenic plants and their genetic relevances discovered. We have also shown that a given MADS box gene can modify the polarity of cell division without affecting the fate of the organ. In vivo interaction between two MADS box genes was demonstrated and the functional dependency of the tomato agamous gene on the TM5 gene product established. We have exploited the Knotted1 meristematic gene in conjunction with tomato leaf meristematic genes to show that simple and compound leaves and, for that matter, sepals and compound leaves, are formed by two different developmental programs. In this context we have also isolated and characterized the tomato Knotted1 gene (TKnl) and studied its expression pattern. A new program in which eight different meristematic genes in tomato will be studied emerged as a result of these studies. In essence, we have shown that it is possible to study and manipulate plant developmental systems using reverse genetic techniques and have provided a wealth of new molecular tools to interested colleagues working with tomato. Similarly, genes responsible for cell division, cell proliferation and cell fate were studied in Arabidopsis floral meristems. Among these genes are the TSO1, TSO2, HANABA TARANU and UNUSUAL FLORAL ORGANS genes, each affecting in its own way the number of pattern of cell divisions, and cell fate, in developing Arabodopsis flowers. In addition, new methods have been established for the assessment of the function of regulatory gene action in the different clonal layers of developing floral meristems.

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Ts'o, P. O. P. Genes and gene expression: Localization, damage and control -- A multilevel and inter-disciplinary study. Office of Scientific and Technical Information (OSTI), September 1990. http://dx.doi.org/10.2172/5192015.

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Ts'o, P. O. P. Genes and gene expression: Localization, damage and control -- A multi-level and interdisciplinary study. Office of Scientific and Technical Information (OSTI), August 1992. http://dx.doi.org/10.2172/7075355.

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Ts'o, P. O. P. Genes and gene expression: Localization, damage and control: A multilevel and inter-disciplinary study. Office of Scientific and Technical Information (OSTI), September 1990. http://dx.doi.org/10.2172/6621658.

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Christian, A. T., M. A. Coleman, and J. D. Tucker. Gene recovery microdissection (GRM) a process for producing chromosome region-specific libraries of expressed genes. Office of Scientific and Technical Information (OSTI), February 2001. http://dx.doi.org/10.2172/15009468.

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Sandford, Erin, Ceren Ciraci, Behnam Abasht, Jack C. M. Dekkers, and Susan J. Lamont. SNPs in Region of NF-Kappa-B Gene Associated with Expression of Immune-Related Genes. Ames (Iowa): Iowa State University, January 2010. http://dx.doi.org/10.31274/ans_air-180814-95.

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Harman, Gary E., and Ilan Chet. Discovery and Use of Genes and Gene Combinations Coding for Proteins Useful in Biological Control. United States Department of Agriculture, September 1994. http://dx.doi.org/10.32747/1994.7568787.bard.

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The objectives of the research in this proposal were to (A) identify synergy among proteins that provide enhanced activity over single proteins for control of plant pathogenic fungi, (B) clone and characterize genetic sequences coding for proteins with ability to control pathogenic fungi, (C) produce transgenic organisms with enhanced biocontrol ability using genes and gene combinations and determine their efficiency in protecting plants against plant pathogenic fungi. A related objective was to produce disease-resistant plants. Fungal cell wall degrading enzymes from any source are strongly synergistic with any membrane active compound and, further, different classes of cell wall degrading enzymes are also strongly synergistic. We have cloned and sequenced a number of genes from bacterial and fungal sources including five that are structurally unrelated. We have prepared transgenic fungi that are deficient in production of enzymes and useful in mechanistic studies. Others are hyperproducers of specific enzymes that permit us, for the first time, to produce enzymes from T. harzianum in sufficient quantity to conduct tests of their potential use in commercial agriculture. Finally, genes from these studies have been inserted into several species of crop plants were they produce a high level of resistance to several plant pathogenic fungi.

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