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Human embryonic stem (ES) cell lines have opened great potential and expectation for cell therapy and regenerative medicine. Monkey and human ES cell lines, which are very similar to each other, have been established from monkey blastocysts and surplus human blastocysts from fertility clinics.Nonhuman primate ES cell lines provide important research tools for basic and applicative research. Firstly, they provide wider aspects of investigation of the regulative mechanisms of stem cells and cell differentiation among primate species. Secondly, their usage does not need clearance or permission from the regulative rules in many countries that are associated with the ethical aspects of human ES cells, although human and nonhuman embryos and fetuses are very similar to each other. Lastly and most importantly, they are indispensable for animal models of cell therapy to test effectiveness, safety, and immunological reaction of the allogenic transplantation in a setting similar to the treatment of human diseases.So far, ES cell lines have been established from rhesus monkey (Macaca mulatta), common marmoset (Callithrix jacchus), and cynomolgus monkey (Macaca fascicularis), using blastocysts produced naturally or by in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). These cell lines seem to have very similar characteristics. They express alkaline phosphatase activity and stage-specific embryonic antigen (SSEA)-4 and, in most cases, SSEA-3. Their pluripotency was confirmed by the formation of embryoid bodies and differentiation into various cell types in culture and also by the formation of teratomas that contained many types of differentiated tissues including derivatives of three germ layers after transplantation into the severe combined immunodeficiency (SCID) mice.The noneffectiveness of the leukemia inhibitory factor (LIF) signal makes culture of primate and human ES cell lines prone to undergo spontaneous differentiation and thus it is difficult to maintain these stem cell colonies. Also, these ES cells are more susceptible to various stresses, causing difficulty with subculturing using enzymatic treatment and cloning from single cells. However, with various improvements in culture methods, it is now possible to maintain stable colonies of monkey ES cells using a serum-free medium and subculturing with trypsin treatment. Under such conditions, cynomolgus monkey ES cell lines can be maintained in an undifferentiated state with a normal karyotype and pluripotency even after prolonged periods of culture over 1 year. Such progress should facilitate many aspects of stem cell research using both nonhuman primate and human ES cell lines.
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Nowak-Kornicka, Judyta, Barbara Borkowska, and Bogusław Pawłowski. "Masculinity and immune system efficacy in men." PLOS ONE 15, no. 12 (December 14, 2020): e0243777. http://dx.doi.org/10.1371/journal.pone.0243777.
Masculinity-related morphological traits are supposed to be honest indicators of a man's biological quality. While some studies showed that sexually dimorphic traits are related to various aspects of biological condition such as general health, immunity or fertility, still little is known about the relationship between masculine traits and the effectiveness of innate and adaptive immunity in humans. The aim of this study was to see if masculine traits, which are dependent on androgen levels in foetal and pubertal stages of development, are related to the immune quality in healthy men. The immune quality was evaluated for 91 healthy men aged 19–36 years. Immunity measurements included innate and adaptive parameters. General health status, age, testosterone level, BMI, physical activity, and smoking were controlled. The shoulder-to-hip ratio (SHR), 2D:4D digit ratio and hand-grip strength (HGS) were used as markers of masculinization. The regressions showed that when controlling for confounds, masculinity-related traits were in general not related to innate and adaptive immunity. Only a weak association was observed for right 2D:4D ratio and T-lymphocyte counts (but it becomes non-significant after adjustment for multiple comparisons). Our results do not support the premise that masculinity is a cue for immunological quality in men. However, the positive association between right 2D:4D and T lymphocytes might suggest that further studies are needed to verify if androgen stimulation in prenatal development might be related to immunity in adulthood.
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Alagawany, Mahmoud, Mohamed Ezzat Abd El-Hack, Mayada Ragab Farag, Marappan Gopi, Kumaragurubaran Karthik, Yashpal Singh Malik, and Kuldeep Dhama. "Rosmarinic acid: modes of action, medicinal values and health benefits." Animal Health Research Reviews 18, no. 2 (November 7, 2017): 167–76. http://dx.doi.org/10.1017/s1466252317000081.
AbstractThe supplementation of livestock rations with herbs containing bioactive components, such as rosmarinic acid (RA), have shown promising results as a natural feed additive in promoting growth, productive and reproductive performance, feed utilization, fertility, anti-oxidant status and immunologic indices. Furthermore, RA reportedly reduces the risks of various animal diseases and mitigates side effects of chemical and synthetic drugs. RA is a natural polyphenol present in several Lamiaceae herbs like Perilla frutescens, and RA is becoming an integral component of animal nutrition as it counters the effect of reactive oxygen species induced in the body as a consequence of different kinds of stressors. Studies have further ascertained the capability of RA to work as an anti-microbial, immunomodulatory, anti-diabetic, anti-allergic, anti-inflammatory, hepato- and renal-protectant agent, as well as to have beneficial effects during skin afflictions. Additionally, RA is favored in meat industries due to enhancing the quality of meat products by reportedly improving shelf-life and imparting desirable flavor. This review describes the beneficial applications and recent findings with RA, including its natural sources, modes of action and various useful applications in safeguarding livestock health as well as important aspects of human health.
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Pinnelli, Antonella, and Mariachiara Di Cesare. "Human fertility: sociodemographic aspects." Contraception 72, no. 4 (October 2005): 303–7. http://dx.doi.org/10.1016/j.contraception.2005.01.008.
Nyland, H., R. Matre, and S. Mörk. "Immunological aspects of human gliomas." Acta Neurologica Scandinavica 63, no. 2 (January 29, 2009): 141–42. http://dx.doi.org/10.1111/j.1600-0404.1981.tb00762.x.
Uibo, Raivo, Andres Salumets, and Gilbert Faure. "Immunological Aspects of Human Reproduction." Clinical and Developmental Immunology 2012 (2012): 1–2. http://dx.doi.org/10.1155/2012/408329.
Butterworth, A. E. "Immunological aspects of human schistosomiasis." British Medical Bulletin 54, no. 2 (January 1, 1998): 357–68. http://dx.doi.org/10.1093/oxfordjournals.bmb.a011693.
Chandra, R. K. "Immunological Aspects of Human Milk." Nutrition Reviews 36, no. 9 (April 27, 2009): 265–72. http://dx.doi.org/10.1111/j.1753-4887.1978.tb07393.x.
Karpati, George, and Montreal Myoblast Transfer Team. "Human myoblast transfer: Immunological aspects." Journal of Neuroimmunology 35 (January 1991): 65. http://dx.doi.org/10.1016/0165-5728(91)90955-7.
Дисертації з теми "Fertility, Human Immunological aspects":
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Ramshaw, Anna Louise. "Immunological aspects of human atherosclerosis." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305549.
Norbeck, Oscar. "Clinical and immunological aspects of human parvovirus B19 infection /." Stockholm : Dept. of laboratory medicine, Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-203-9/.
Clarke, Damian. "Essays on fertility and family size." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:94016283-a3dd-4b6a-8427-373b49a491be.
In these papers I discuss the causal estimation of the effects of fertility and fertility planning developments on mother and child outcomes. A number of concerns are raised with existing identification techniques, and alternative methodologies to consistently estimate the effect of interest are proposed. These concerns and new techniques are illustrated using microdata on slightly more than 43,000,000 births ocurring between 1972 and 2013. In the first substantive chapter (written with Sonia Bhalotra), we discuss the validity of the use of twin births in fertility research. We demonstrate that twin births are not random. Successfully taking twins to term depends upon positive maternal health behaviours and investments in the periods preceding birth. We show that this is of considerable concern for estimation techniques which rely on twin births being (conditionally) randomly assigned to identify causal effects. To illustrate, we consider the estimation of the child quantity-quality (QQ) trade-off, and show that existing instrumental variable estimates are inconsistent in the contexts examined. Upon partially correcting for the fact that twin births are not random, a statistically significant QQ trade-off begins to emerge. We close by examining a number of partial identification techniques to bound the true effect of fertility on child outcomes. In the second substantive chapter, I examine the effect of fertility control policies on the fertility decisions and outcomes of women. I consider the case of the emergency contraceptive pill in Chile. The staggered arrival of this technology to Chile over the last decade has resulted in the availability of the first safe and legal post-coital birth control policies. In a context of high teenage pregnancy rates, difference-in-difference (DD) style estimates suggest that this policy has accounted for reductions in short-term teen childbearing by as much as 7%, an effect similar to the arrival of abortion in the USA. This policy is also shown to reduce fetal deaths reported in early gestation with no similar reduction in late gestation: suggestive evidence that an alternative fertility control policy may reduce costly and dangerous illegal abortions. Finally, I turn to the use of DD estimators as a policy-analysis tool. I discuss how such estimators perform in the case of reforms which may not be sharply demarcated to treatment and control clusters, but rather subject to local spillovers or externalities. I propose an extension of the typical DD estimator: a spillover-robust DD estimator. This methodology is applied to estimate the effect of two localised fertility control reforms in Mexico and Chile, where women close to treatment clusters who were not themselves subject to the reform may nonetheless travel to access treatment.
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Wu, Yuet, and 吳越. "Immune response of human monocyte-derived dendritic cells to co-infection of influenza virus and Streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45543732.
McKenna, Kenneth A. (Kenneth Allen). "Assessing the Psychological Impact of Fertility Treatment." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc277704/.
This controlled descriptive study was designed to investigate the psychological status of couples who are engaged in advanced fertility treatments. A battery of psychological test instruments, including the Millon Behavioral Health Inventory (MBHI), the Health Attribution Test (HAT), the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), and the Marlowe-Crowne Social Desirability Scale (MCSDS), was used to measure psychological variables that have been shown in the infertility research literature to be associated with the psychological experiences of infertility patients. The scores from the four assessment instruments were compared with those of pregnant couples in childbirth education classes to differentiate the impact of stress associated with fertility treatment from the stress experienced by third trimester pregnant couples. Eighty-five subjects (42 male and 43 female) volunteered for the study and completed packets of questionnaires. The groups were designated Treatment (infertile couples) and Control (pregnant couples). The resulting data were collected and analyzed on the basis of group mean scores on the test instruments.
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Qin, Gang, and 秦刚. "The immunological roles of human gammadelta T lymphocytes in influenzavirus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46477354.
Yip, Ming-shum, and 葉名琛. "Severe acute respiratory syndrome coronavirus infection of human immune cells through antibody-mediated pathway." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46542139.
Yip, Ming-shum, and 葉名琛. "Immune responses of human respiratory epithelial cells to respiratory syncytial virus and human metapneumovirus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3955725X.
SORENSON, ANN MARIE. "ETHNICITY AND FERTILITY: THE FERTILITY EXPECTATIONS AND FAMILY SIZE OF MEXICAN-AMERICAN AND ANGLO ADOLESCENTS AND ADULTS, HUSBANDS AND WIVES (BIRTHS, HISPANIC)." Diss., The University of Arizona, 1985. http://hdl.handle.net/10150/188137.
Because pronatalist sentiments may be an important aspect of Mexican-American ethnic heritage, this research focuses on cultural as well as socioeconomic factors which may contribute to higher Mexican-American fertility. Language use and nativity are used as indirect indicators of identification with an ethnic culture. Wives' characteristics are generally considered adequate to the study of couples' fertility, but in light of earlier research by the author indicating the importance of cultural factors to the fertility expectations of Mexican-American adolescent males, characteristics of husbands as well as wives are included in this analysis. For this reason, the sample, which is drawn from the 1980 Census data for Arizona, Texas, and New Mexico, is limited to Mexican-American and Anglo women who have been married only once and live with their husbands. Two complementary methods of analysis are used. Linear regression describes the significance of husband's and wife's language use, nativity, and socioeconomic characteristics to mean family size. Parity progression ratios are used to study the contribution of these variables to the likelihood of the addition of one more child at each stage of the family building process. While wife's characteristics are sufficient to account for most of the variation observed in Anglo fertility, husband's socioeconomic characteristics significantly contribute to variation observed in the fertility of Mexican-American couples. Husbands' identification with Mexican-American culture may be somewhat more important to couples' fertility than that of their wives. This is consistent with research which suggests that children are more central to male sex role expectations as they are expressed in the context of Mexican-American culture than in that of Anglos. The measures of ethnic identity used in this study are clearly associated with socioeconomic status. The differential fertility of Anglos and Mexican Americans could be attributed to these differences. The association of Spanish language use and fertility has been linked to the lower opportunity costs represented by additional children to women who do not speak English proficiently. However, the analysis of these data, which compares structural and cultural explanations of fertility differentials, provides evidence of cultural effects as well as the effects of socioeconomic status on fertility.
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Yuan, Tingting, and 袁婷婷. "Identification of intermediate antibodies of broadly neutralizing HIV-1 human monoclonal antibody b12 and characterization of variable loops of HIV-1 envelop glycoprotein." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196445.
Книги з теми "Fertility, Human Immunological aspects":
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International Symposium on Immunological Approaches to Contraception and Promotion of Fertility (1985 Fogarty International Center). Immunological approaches to contraception and promotion of fertility. New York: Plenum Press, 1986.
World Congress on Fertility and Sterility (13th 1989 Marrakech, Morocco). New concepts in reproduction: The proceedings of the XIII World Congress on Fertility and Sterility, Marrakesh, October 1989. Carnforth, Lancs, UK: Parthenon Pub. Group, 1991.
Eugenics Society (London, England). Symposium. Natural human fertility: Social and biological determinants : proceedings of the Twenty-Third Annual Symposium of the Eugenics Society, London, 1986. London: Macmillan in association with the Society, 1988.
Wakam, Jean. De la pertinence des théories "économistes" de fécondité dans le contexte socio-culturel camerounais et negro-africain. [Yaoundé]: Institut de formation et de recherche démographiques, 1994.
Symposium, Eugenics Society Annual. Natural human fertility: Social and biological determinants : proceedings of the Twenty-Third Annual Symposium of the Eugenics Society, London, 1986. London: Macmillan in association with the Eugenics Society, 1988.
Частини книг з теми "Fertility, Human Immunological aspects":
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Talwar, G. P., and A. Gaur. "Immunological Aspects of Fertility Regulation." In Female Contraception, 345–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73790-9_33.
Hilders, Carina G. J. M., Jaap D. H. van Eendenburg, Yvonne Nooyen, and Gert Jan Fleuren. "Immunological Aspects of Cervical Carcinoma." In Immunology of Human Papillomaviruses, 243–48. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2449-6_38.
Singh, Gurpreet. "Monoclonal Antibodies Against Human Sperm." In Immunological Approaches to Contraception and Promotion of Fertility, 201. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_23.
Reddy, Vemuri B., Anton K. Beck, Vincent Vellucci, Anthony J. Garramone, and Edward G. Bernstine. "Cloning and Expression of Biologically Active Human Fertility Hormones." In Immunological Approaches to Contraception and Promotion of Fertility, 77–91. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_11.
Yan, Yuan Chang, Lin Fang Wang, Sumi M. Mitsudo, and S. S. Koide. "Characterization of an Antisperm Monoclonal Antibody Inducing Human Sperm Agglutination." In Immunological Approaches to Contraception and Promotion of Fertility, 231–40. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_27.
Isojima, Shinzo, Koji Koyama, Minoru Shigeta, Akiko Hasegawa, Stanimir D. Kyurkchiev, Kinu Kameda, Yukio Tsunoda, and Takashi Nagai. "Purification of Human Gamete Antigens Relevant to Antibody Production: Application of Monoclonal Antibodies." In Immunological Approaches to Contraception and Promotion of Fertility, 323–33. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_35.
Griffin, P. D. "A Fertility Regulating Vaccine Based on the Carboxyl-Terminal Peptide of the Beta Subunit of Human Chorionic Gonadotrophin." In Immunological Approaches to Contraception and Promotion of Fertility, 43–59. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_8.
Beer, Alan E., Zhu Xiaoyu, A. E. Semprini, and James F. Quebbeman. "Pregnancy Outcome in Human Couples with Idiopathic Recurrent Abortions: The Role(s) of Female Serum, Mixed Lymphocyte Culture Blocking Factors, Potentiating Factors, and Local Uterine Immunity Before and After Paternal Leukocyte Immunization." In Immunological Approaches to Contraception and Promotion of Fertility, 393–406. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_41.
Webb, Paul D., Nicholas Hole, P. Jeremy McLaughlin, Peter L. Stern, and Peter M. Johnson. "Biochemical and Immunological Aspects of the Human Trophoblast Cell Surface." In Cellular Biology and Pharmacology of the Placenta, 3–15. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4757-1936-9_1.
Kanzaki, Hideharu, and Takahide Mori. "Immunological Regulation of Endometrial Function: Cytokine Production in the Human Endometrium." In Molecular and Cellular Aspects of Periimplantation Processes, 288–300. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2548-5_19.
Тези доповідей конференцій з теми "Fertility, Human Immunological aspects":
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Nişancı, Murat, Aslı Cansın Doker, Adem Türkmen, and Ömer Selçuk Emsen. "The Determinants of Labor Productivity: Analyses on Chosen Countries (1960-2010)." In International Conference on Eurasian Economies. Eurasian Economists Association, 2016. http://dx.doi.org/10.36880/c07.01550.
Discussions on economic productivity, in micro analysis aspects there is direct causal relationship between increases or decreases in the production and productivity, whereas it can be said that productivity is based on economic recession or growth in macro analysis aspects. In the literature, while Classical theoreticians is attributed that the source of growth is the marginal productivity of capital, neoclassic school claims that marginal productivity difference provide benefit the country from behind for realization of the convergence hypothesis. Furthermore, increasing efficiency and as the factors this increase efficiency human capital, learning by doing concepts and technology are focused in the endogenous growth theories. In this study, human capital, physical capital per worker, exports per worker, gender differences, fertility, life expectancy and dependent population ratio were determined as determinants of labor productivity. In respect to labor productivity, variables are divided to three main groups in order to economic demographic and social and psychological factors. The variables are placed with taking five years average due to the fact that those variables’ effects reveal themselves more clearly in the long term. In the paper, it was investigated by panel data analysis considering groups of developed and developing countries between 1960 and 2010 period. In this context the degree of efficiency may well be discussed with parameters of selected variables for productivity of labor. Additionally, within framework of descriptive statistics the differences and similarities between countries were interpreted for political recommendations to developing countries how to increase productivity for catching developed countries’ growth trend.
