Добірка наукової літератури з теми "Expression à la surface de la levure"
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Статті в журналах з теми "Expression à la surface de la levure":
Köster, B., and M. Strand. "Schistosoma mansoni: immunolocalization of two different fucose-containing carbohydrate epitopes." Parasitology 108, no. 4 (May 1994): 433–46. http://dx.doi.org/10.1017/s0031182000075995.
Creson, Jennifer R., Andy A. Lin, Qun Li, David F. Broad, Margo R. Roberts, and Stephen J. Anderson. "The Mode and Duration of Anti-CD28 Costimulation Determine Resistance to Infection by Macrophage-Tropic Strains of Human Immunodeficiency Virus Type 1 In Vitro." Journal of Virology 73, no. 11 (November 1, 1999): 9337–47. http://dx.doi.org/10.1128/jvi.73.11.9337-9347.1999.
Bagashev, Asen, Elena Sotillo, Glendon Wu, and Andrei Thomas-Tikhonenko. "The Importance of CD19 Exon 2 for Surface Localization: Closing the Ig-like Loop." Blood 126, no. 23 (December 3, 2015): 3433. http://dx.doi.org/10.1182/blood.v126.23.3433.3433.
Labroussaa, Fabien, Vincent Baby, Sébastien Rodrigue, and Carole Lartigue. "La transplantation de génomes." médecine/sciences 35, no. 10 (October 2019): 761–70. http://dx.doi.org/10.1051/medsci/2019154.
RAHAMIMOFF, HANNAH, XIAOYAN REN, CHAVA KIMCHI-SARFATY, SURESH AMBUDKAR, and JUDITH KASIR. "NCX1 Surface Expression." Annals of the New York Academy of Sciences 976, no. 1 (January 24, 2006): 176–86. http://dx.doi.org/10.1111/j.1749-6632.2002.tb04739.x.
Käfer, G., A. Willer, W. D. Ludwig, A. Krämer, R. Hehlmann, and J. Hastka. "Intracellular expression of CD61 precedes surface expression." Annals of Hematology 78, no. 10 (October 21, 1999): 472–74. http://dx.doi.org/10.1007/s002770050601.
Kanematsu, Takashi, Makoto Fujii, Hiroto Tanaka, Hisanori Umebayashi, and Masato Hirata. "Surface Expression of GABAA Receptors." Journal of Oral Biosciences 52, no. 4 (January 2010): 322–29. http://dx.doi.org/10.1016/s1349-0079(10)80012-x.
Dunbar, Andrew, Min Lu, Mirko Farina, Young Park, Julie Yang, Dongjoo Kim, Abdul Karzai, et al. "Increased Interleukin-8 (IL8)-CXCR2 Signaling Promotes Progression of Bone Marrow Fibrosis in Myeloproliferative Neoplasms." Blood 136, Supplement 1 (November 5, 2020): 6–7. http://dx.doi.org/10.1182/blood-2020-138843.
Swamynathan, Shivalingappa K. "Ocular Surface Development and Gene Expression." Journal of Ophthalmology 2013 (2013): 1–22. http://dx.doi.org/10.1155/2013/103947.
Pope, Kevin O., Adriana C. Ocampo, Gary L. Kinsland, and Randy Smith. "Surface expression of the Chicxulub crater." Geology 24, no. 6 (1996): 527. http://dx.doi.org/10.1130/0091-7613(1996)024<0527:seotcc>2.3.co;2.
Дисертації з теми "Expression à la surface de la levure":
Pruvost, Tiphanie. "Ingénierie moléculaire de la réactivité croisée inter-espèces d’anticorps thérapeutiques par Yeast Surface Display." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASQ074.
Success of the monoclonal antibodies as therapeutic tools is partly due to their high specificity for their targets. Because of this high specificity antibodies developed against a human target often fail to recognize this target in animals used as models in preclinical trials. Thus, the goal of this study is to develop a protein engineering method aiming at conferring an antibody the ability to recognize a same antigen belonging to different species. To do so, two antibodies recognizing the human LAMP1 protein but not the murine and simian LAMP1 are used as models. In this project an exhaustive mutagenesis (DMS) monitored by Yeast Surface Display (YSD) and flow cytometry. The first part describes how these technics are combined in order to identify the epitopes of two antibodies on human LAMP1. The amino acids of epitopes are compared to those of murine and simian LAMP1 to explain the lack of recongnition of this two proteins. The second part focuses on the engineering strategy developped on the two antibodies. The expression of the DMS libraries in YSD allowed to select single mutations improving the cross-reactivity on LMAP1 without affecting the functionality of the antibodies. These mutations have been combined in a second library that has been screened for promissing variants. The affinities of these variants for differents human et simian LAMP1 orthologs has been measured to confirm the succes of the strategy. For each antibody many cross-reactive variants have been obtained
Sivelle, Coline. "Conception et production d’anticorps anti-TNFa non immunogènes pour le traitement des maladies inflammatoires." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS603.
Efficacy of anti-TNFα antibodies is well known to be affected by their immunogenicity. Some patients developp anti-drug antibodies (ADA) which can elicit adverse effects and neutralize the therapeutic protein. Adalimumab (Humira®), which is the most used anti-TNFα, is reported to be immunogenic for more than 30% of patients in some diseases. T-cell epitopes that account for its immunogenicity are mostly carried by regions implied in the interaction with TNFα. In the present work, we propose to remove T-cell epitopes from the antibody sequence while maintaining its functionality.To undertake this issue, this PhD project uses Yeast Surface Display (YSD) to monitor the affinity of the biologic during the mutagenesis process. To do so, a comparison of different expression formats of antibody in YSD has been performed in order to define the format that will be used for the deimmunization method. Then, the strategy chosen to reduce immunogenicity is based on T-cell epitopes removal. First, it merges deep mutational scanning and in silico HLA II binding prediction to identify substitutions deleterious for HLA II/T-cell epitopes interaction while neutral for the function of the biologic. Secondly, these substitutions were combined to obtain libraries pre-enriched with functional sequences. Mutants with reduced immunogenic potential were then selected from these libraries. Several mutants of adalimumab with reduced immunogenicity potential according to HLA II binding prediction were identified and caracterized. All of them show an increased affinity for TNFα associated with an improvement of activity of at least two fold in comparison to adalimumab
Kudla, Bernard. "Construction d'un vecteur d'expression pour la levure Schizosaccharomyces pombe." Paris 11, 1987. http://www.theses.fr/1987PA112080.
Klonowska, Agnieszka. "Expression hétérologue de laccases du champignon Marasmius quercophilus chez la levure Saccharomyces cerevisiae." Aix-Marseille 3, 2000. http://www.theses.fr/2000AIX30085.
The basidiomycete Marasmius quercophilus colonizes the decaying litter of the evergreen oak (Quercus ilex L. ). This mushroom uses several enzymes to degrade lignin in order to have an access to cellulose. In vitro, it has a strong phenol oxidation activity related to the expression of several laccase isoforms among which Lac1 is predominant. Using molecular oxygen to oxidise numerous substrates, these copper enzymes are at the heart of many biotechnological projects. From controled culture conditions, we purified and partially characterized three laccase isoforms other than Lac1. Four members of the multigenic family which encodes laccases were cloned and sequenced. Among these genes, lac1, the structural gene encoding the major isoform, was formaly identified. The complementary DNA corresponding to these genes were expressed in the yeast Saccharomyces cerevisiae. Two of them, cDNA17 (lac1) and cDNA20, lead to the synthesis of secreted active laccases
Lacour, Thierry. "Expression du cytochrome p45011 bovin dans la levure : identification d'un nouveau transporteur d'electrons." Université Louis Pasteur (Strasbourg) (1971-2008), 1997. http://www.theses.fr/1997STR13101.
Boutabout, Mansour. "La Rétrotranscriptase de l'élément Ty1 de la levure Saccharomyces cerevisiae : Clonage, expression, fidélité." Université Louis Pasteur (Strasbourg) (1971-2008), 2002. http://www.theses.fr/2002STR13157.
Kribii, Rachida. "La squalène synthase d'Arabidopsis thaliana - caractérisation moléculaire et expression chez la levure Saccharomyces cerevisiae." Poitiers, 1996. http://www.theses.fr/1996POIT2390.
CORREDOR, RODRIGUEZ MAURICIO. "Diversite genetique, constitution chromosomique et expression genetique chez la levure fromagere halotolerant debaryomyces hansenii." Paris 11, 2001. http://www.theses.fr/2001PA112044.
Helies-Toussaint, Cécile. "Expression des genes dans le testicule." Paris 11, 1996. http://www.theses.fr/1996PA11T012.
Verdiere, Jacqueline. "Régulation de la synthèse de l'iso 2-cytochrome c chez la levure Saccharomyces cerevisiae." Paris 11, 1987. http://www.theses.fr/1987PA112281.
Книги з теми "Expression à la surface de la levure":
Leung, Roland. Persistence of procoagulant surface expression by activated platelets. Ottawa: National Library of Canada, 2003.
Barbosa, Isabel Leal. The expression of surface antigens and phagocytic activity by human monocytes and alveolar macrophages. Uxbridge: Brunel University, 1989.
Francqui Colloquium (3rd 1997 Brussels, Belgium). The trypanosome surface: Proceedings of the Third Francqui Colloquium, 26-27 May 1997, Brussels. Paris: De Boeck Université, 1999.
1953-, Benovic Jeffrey L., ed. Regulation of G protein-coupled receptor function and expression. New York: Wiley-Liss, 2000.
Michael, Conn P., ed. Gene expression in neural tissues. San Diego, Calif: Academic Press, 1992.
Ali, Saima. Regulation of the cell surface expression and the function of GABA(B)R1a by GABA(B)R2. Ottawa: National Library of Canada, 2000.
Kelleher, Mittie Elizabeth. Relationship of BE2 surface antigen expression to T-cell clonality in cutaneous T-cell lymphoma and scleroderma. [New Haven: s.n.], 1990.
Smith, Alan L. The volcanic geology of the Mid-Arc Island of Dominica, Lesser Antilles: The surface expression of an Island-Arc batholith. Boulder, Colorado, USA: The Geological Society of America, 2013.
Robinson, Elizabeth M. The effect of a shallow low viscosity zone on mantle flow and its expression at the surface of the earth. Woods Hole, Mass: Woods Hole Oceanographic Institution, 1987.
Tooze, Jennifer Anne. Cell surface and molecular expression of immunoregulatory determinants on B-Cell chronic lymphocytic leukaemia cells and their putative normal lineage counterparts. Uxbridge: Brunel University, 1993.
Частини книг з теми "Expression à la surface de la levure":
Wang, Zhiguo, and Baofeng Yang. "Surface-Enhanced Raman Spectroscopy Method." In MicroRNA Expression Detection Methods, 275–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04928-6_20.
Mras, Gabriele M. "‘Surface’ as an expression of an intention." In Wollheim, Wittgenstein, and Pictorial Representation, 160–68. 1 [edition]. | New York: Routledge, 2016.: Routledge, 2016. http://dx.doi.org/10.4324/9781315640983-7.
Schräml, Michael, D. Ambrosius, and M. Lanzendörfer. "Rapid Generation of Protein Variants and Subsequent Analysis by Surface Plasmon Resonace." In Cell-Free Protein Expression, 69–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-59337-6_9.
Young, Mark T. "Studying Purinoceptor Cell-Surface Expression by Protein Biotinylation." In Methods in Molecular Biology, 137–46. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9717-6_9.
Yi, Feng, Stephen F. Traynelis, and Kasper B. Hansen. "Selective Cell-Surface Expression of Triheteromeric NMDA Receptors." In Methods in Molecular Biology, 145–62. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7321-7_7.
Heuner, Klaus, Michael Steinert, Claudia Dietrich, Gunter Fischer, Rolf Köhler, and Jörg Hacker. "Function and Expression of Legionella pneumophila Surface Factors." In Legionella, 43–48. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555817985.ch8.
Yi, Feng, Stephen F. Traynelis, and Kasper B. Hansen. "Selective Cell-Surface Expression of Triheteromeric NMDA Receptors." In Methods in Molecular Biology, 55–77. New York, NY: Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3830-9_5.
Jones, David T., Dagoberto Monroy, Zhongua Ji, and Stephen C. Pflugfelder. "Alterations of Ocular Surface Gene Expression in Sjögren’s Syndrome." In Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2, 533–36. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5359-5_75.
Lam, Clarissa, Mahmud Arif Pavel, Parul Kashyap, Zahra Salehi-Najafabadi, Victoria Valentino, and Yong Yu. "Detection of CXCR2 Cytokine Receptor Surface Expression Using Immunofluorescence." In Cytokine Bioassays, 193–200. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0928-5_17.
Ujir, Hamimah, Michael Spann, and Irwandi Hipni Mohamad Hipiny. "3D Facial Expression Classification Using 3D Facial Surface Normals." In Lecture Notes in Electrical Engineering, 245–53. Singapore: Springer Singapore, 2014. http://dx.doi.org/10.1007/978-981-4585-42-2_29.
Тези доповідей конференцій з теми "Expression à la surface de la levure":
"Expression of Surface Molecules in Hematological Malignancies." In INTERNATIONAL CONFERENCE ON BIOLOGICAL RESEARCH AND APPLIED SCIENCE. Jinnah University for Women, 2024. http://dx.doi.org/10.37962/ibras/2024/70-73.
Boukobza, Ram, and Ari Rappoport. "Multi-word expression identification using sentence surface features." In the 2009 Conference. Morristown, NJ, USA: Association for Computational Linguistics, 2009. http://dx.doi.org/10.3115/1699571.1699573.
Geller, David S., Sheref E. Hassan, and Richard Gorlick. "Abstract 5104: Cell-surface receptor expression in osteosarcoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5104.
Ahn, Dae-Keon, Soon-Man Kwon, and Seok-Hee Lee. "Expression for Surface Roughness Distribution of FDM Processed Parts." In 2008 International Conference on Smart Manufacturing application (ICSMA). IEEE, 2008. http://dx.doi.org/10.1109/icsma.2008.4505572.
Masoni, I., R. Brossier, J. L. Boelle, and J. Virieux. "Generic Gradient Expression for Robust FWI of Surface Waves." In 76th EAGE Conference and Exhibition 2014. Netherlands: EAGE Publications BV, 2014. http://dx.doi.org/10.3997/2214-4609.20141407.
Civelekoglu, Ozgun, Ningquan Wang, Mert Boya, Tevhide Ozkaya-Ahmadov, Ruxiu Liu, and A. Fatih Sarioglu. "Quantitative Measurement of Cell Surface Expression Via Magnetophoretic Cytometry." In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE, 2019. http://dx.doi.org/10.1109/transducers.2019.8808437.
Machiraju, S., N. Arger, B. Benn, A. Sommer, N. Bhakta, and L. Koth. "Differential Expression of Monocyte Cell Surface Proteins in Pulmonary Sarcoidosis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4511.
Richman, Sarah A., Liang-Chuan Wang, Edmund K. Moon, Steven M. Albelda, and Michael C. Milone. "Abstract 2294: Reversible regulation of chimeric antigen receptor surface expression." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2294.
Gralnick, H. R., L. M. Magurder, K. Hansmann, M. Vail, G. Marti, R. McEver, and S. Williams. "THE SURFACE EXPRESSION OF ALPHA GRANULE PROTEINS FOLLOWING THROMBIN STIMULATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643859.
Hashimoto, M., and D. Morooka. "Facial expression of a robot using a curved surface display." In 2005 IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE, 2005. http://dx.doi.org/10.1109/iros.2005.1545357.
Звіти організацій з теми "Expression à la surface de la levure":
Chaney, William G. Control of Metastasis-Associated Gene Expression by Cell-Surface Beta-1, 6 Branched Oligosaccharide Expression. Fort Belvoir, VA: Defense Technical Information Center, June 2002. http://dx.doi.org/10.21236/ada413058.
Zaharieva, Emanuela, Elena Vikentieva, Rosica Andreeva, Dora Popova, and Zdravko Kamenov. CD36 Surface Expression on Monocytes in Type 2 Diabetes. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, April 2018. http://dx.doi.org/10.7546/crabs.2019.04.14.
Chaney, William G. Control of Metastasis-Associated Gene Expression by Cell-Surface Beta-1,6 Branched Oligosaccharide Levels. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada420126.
Ching, Kathryn. Differential Control of ErbB2 Surface Expression in Breast Cancer Cells by an Alternatively Spliced Form of ERBIN. Fort Belvoir, VA: Defense Technical Information Center, May 2004. http://dx.doi.org/10.21236/ada427073.
Peck, Jeremy W. Differential Control of ErbB2 Surface Expression in Breast Cancer Cells by an Alternatively Spliced Form of ERBIN. Fort Belvoir, VA: Defense Technical Information Center, May 2003. http://dx.doi.org/10.21236/ada416779.
Brent L. Iverson, George Georgiou, Mohammad M. Ataai, and Richard R. Koepsel. New Strategies for Designing Inexpensive but Selective Bioadsorbants for Environmental Pollutants: Selection of specific Ligands and Their Cell Surface Expression. Office of Scientific and Technical Information (OSTI), February 2001. http://dx.doi.org/10.2172/789805.
Iverson, B. L., G. Georgiou, M. M. Ataai, and R. R. Koepsel. New strategies for designing inexpensive but selective bioadsorbants for environmental pollutants: Selection of specific ligands and their cell surface expression. 1998 annual progress report. Office of Scientific and Technical Information (OSTI), June 1998. http://dx.doi.org/10.2172/13502.
Iverson, B. New strategies for designing inexpensive but selective bioadsorbants for environmental pollutants: Selection of specific ligands and their cell surface expression. Technical progress report, September 15, 1996--September 14, 1997. Office of Scientific and Technical Information (OSTI), January 1997. http://dx.doi.org/10.2172/13501.
Neodo, Anna, Fiona Augsburger, Jan Waskowski, Joerg C. Schefold, and Thibaud Spinetti. Monocytic HLA-DR expression and clinical outcomes in adult ICU patients with sepsis – a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0119.
Cruikshank, K. M., A. M. Johnson, R. W. Fleming, and R. L. Jones. Winnetka deformation zone: Surface expression of coactive slip on a blind fault during the Northridge earthquake sequence, California. Evidence that coactive faulting occurred in the Canoga Park, Winnetka, and Northridge areas during the 17 January 1994, Northridge, California earthquake. Office of Scientific and Technical Information (OSTI), December 1996. http://dx.doi.org/10.2172/677055.