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Добірка наукової літератури з теми "Diazonia"

Автор: Grafiati

Опубліковано: 14 вересня 2024

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Статті в журналах з теми "Diazonia"

Estienne, J., O. Cerclier, and J. J. Rosenberg. "Powder diffraction data of two tricydic diazonia diiodide salts used in silver iodide solid electrolytes." Powder Diffraction 8, no. 3 (September 1993): 175–79. http://dx.doi.org/10.1017/s0885715600018145.

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Indexed X-ray powder diffraction data are reported for two organic salts with carbon rings having two quaternary nitrogens: diazonia-6,9 dispiro [5.2.5.2] hexadecane and diazonia-6,9 dispiro [5.2.5.3] heptadecane diiodides. For these compounds, which give solid electrolytes when associated with AgI, powder diffraction diagrams calculated by the Rietveld method from single crystal structure determinations are presented and are compared to the experimental diffraction data.

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Yousefi, Mohammad, Vahid Amani, and Hamid Reza Khavasi. "1,10-Diazonia-18-crown-6 dichloride." Acta Crystallographica Section E Structure Reports Online 63, no. 9 (August 10, 2007): o3782. http://dx.doi.org/10.1107/s160053680703807x.

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Kliegel, Wolfgang, Ulf Riebe, Steven J. Rettig, and James Trotter. "Structural studies of organoboron compounds XLVIII. 1,4-Diphenyl-3,3:6,6-bis(tetramethylene)-2,5,7-trioxa-3,6-diazonia-1,4-diboratabicyclo[2.2.1]heptane." Canadian Journal of Chemistry 69, no. 8 (August 1, 1991): 1222–26. http://dx.doi.org/10.1139/v91-182.

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The reaction of N-hydroxypyrrolidine with either oxybis(diphenylborane) or phenylboronic acid gives 1,4-diphenyl-3,3:6,6-bis(tetramethylene)-2,5,7-trioxa-3,6-diazonia-1,4-diboratabicyclo[2.2.1]heptane in moderate yield. Crystals of the product are orthorhombic, a = 10.984(2), b = 14.619(2), c = 12.311(2) Å, Z = 4, space group Pccn. The structure was solved by direct methods and was refined by full-matrix least-squares procedures to R = 0.039 and Rw = 0.043 for 908 reflections with I ≥ 3σ(I). This is the first heterocyclic [2.2.1]heptane system containing a six-membered BONBON ring and a B—O—B bridge to be structurally characterized. The molecule has exact C2 symmetry with the twofold axis passing through the bridging oxygen atom. Bond lengths involving the tetrahedrally coordinated boron atom are B—O(B) = 1.423(3), B—O(N) = 1.497(3), B—N = 1.703(3), and B—C(phenyl) = 1.577(4) Å. Key words: 2,5,7-trioxa-3,6-diazonia-1,4-diboratabicyclo[2.2.1]heptane ring system, crystal structure, organoboron compound.

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Gharbi, A., and A. Jouini. "4,9-Diazonia-1,12-dodecanediammonium Dilithium cyclo-Hexaphosphate Tetrahydrate." Acta Crystallographica Section C Crystal Structure Communications 52, no. 6 (June 15, 1996): 1342–44. http://dx.doi.org/10.1107/s0108270196000558.

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Söhnel, Tilo, Kathrin A. Wichmann, Thomas Doert, and Garth J. S. Cooper. "3,12-Diaza-6,9-diazonia-2,13-dioxotetradecane bis(perchlorate)." Acta Crystallographica Section E Structure Reports Online 68, no. 2 (January 11, 2012): o333—o334. http://dx.doi.org/10.1107/s1600536811055516.

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Yousefi, Mohammad, Shabahang Teimouri, Vahid Amani, and Hamid Reza Khavasi. "1,10-Diazonia-18-crown-6 hexachloridoplatinate(IV) dihydrate." Acta Crystallographica Section E Structure Reports Online 63, no. 10 (September 1, 2007): m2460—m2461. http://dx.doi.org/10.1107/s1600536807042341.

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Miller, Norman E., and Don L. Reznicek. "Chemistry of 1,1,4,4-tetramethyl-1,4-diazonia-2,5-diboratacyclohexane." Journal of Organometallic Chemistry 349, no. 1-2 (July 1988): 11–22. http://dx.doi.org/10.1016/0022-328x(88)80432-7.

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Miller, Norman E. "Stereochemistry of a 2,5-disubstituted 1,4-diazonia-2,5-diboratacyclohexane." Inorganic Chemistry 27, no. 12 (June 1988): 2196–200. http://dx.doi.org/10.1021/ic00285a038.

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Srinivasan, Bikshandarkoil R., Christian Näther, Sunder N. Dhuri, and Wolfgang Bensch. "Cation–anion interactions in bis(±)trans-2-aminocyclohexylammonium tetrathiotungstate, 1,7-diazonia-4-aza-heptane tetrathiotungstate and 1,5-diazonia-9-aza-nonane tetrathiotungstate." Polyhedron 25, no. 17 (December 2006): 3269–77. http://dx.doi.org/10.1016/j.poly.2006.05.039.

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Estienne, J. "Structure de l'octaiodotétraargentate de bis(diazonia-6,9 dispiro[5.2.5.3]heptadécane)." Acta Crystallographica Section C Crystal Structure Communications 42, no. 11 (November 15, 1986): 1512–16. http://dx.doi.org/10.1107/s0108270186091655.

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Більше джерел

Дисертації з теми "Diazonia"

Labro, Marine. "Synthèse de nouvelles prodrogues photoactivables ciblant les G-quadruplexes : étude de la photoréaction et design moléculaire pour améliorer la biocompatibilité et l'efficacité d'une nouvelle thérapie anti-cancer." Electronic Thesis or Diss., Lyon, École normale supérieure, 2024. http://www.theses.fr/2024ENSL0020.

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Le cancer est un problème de santé publique majeur : en 2020, il a causé la mort d’environ 10 millions d’individus dans le monde soit l’équivalent d’une mort sur six. Les recherches récentes contre le cancer ont conduit à l’émergence de thérapies innovantes plus ciblées. Ainsi, les dommages collatéraux aux cellules saines et donc les effets secondaires chez les patients traités sont limités, tout en garantissant une efficacité maximale du traitement pour l’éradication de la tumeur. Dans ces travaux de thèse, nous étudions une nouvelle réaction photochimique originale permettant le développement d’une nouvelle prodrogue anti-cancéreuse photoactivable. À partir d’une molécule hélicoïdale de type bis-quinoléine, une photoréaction intramoléculaire de double SNAr* conduit à la formation d’un diazonia étendu, ligand des G-quadruplexes de l’ADN, fluorescent, et capable de générer de l’oxygène singulet cytotoxique. Ainsi, cette réaction photochimique permet le développement d’un traitement anti-cancéreux nouveau à la croisée entre la photothérapie dynamique et le photo-cageage. De plus, la lumière est un stimulus extérieur non-nocif dans une certaine gamme de longueur d’onde (notamment infra-rouge) et qui permet une libération du médicament contrôlé spatio-temporellement ce qui en fait un mode d’action de la prodrogue très ciblé et prometteur. Dans cette thèse, nous avons appréhendé le mécanisme de la photoréaction par étude de l’effet de différents paramètres expérimentaux physico-chimiques. Aussi, nous avons rationalisé l’influence de la nature du groupe partant sur l’efficacité de la double SNAr* et sur le rendement quantique de la photoréaction. Ensuite, nous avons amélioré le design de la prodrogue en vue de son application biologique afin de 1) assurer la biocompatibilité du traitement par déclenchement de la photoréaction dans la fenêtre de transparence biologique 2) améliorer l’internalisation cellulaire de la prodrogue 3) développer une thérapie combinée par association de plusieurs agents anticancéreux et mise en place de stratégies de ciblage
Cancer is a major public health problem: in 2020, it caused the death of approximately 10 million people worldwide, equivalent to one in six deaths. Recent research efforts against cancer have led to the emergence of targeted and innovative therapies. These advancements aim to minimize collateral damage to healthy cells and reduce side effects in treated patients, while ensuring maximum treatment efficacy for tumor eradication. In this thesis, we study a new original photochemical reaction allowing the development of a new photoactivatable anti-cancer prodrug. From a helical molecule of bis-quinoline type, an intramolecular double SNAr* photoreaction leads to the formation of an extended diazonia, a G-quadruplexes ligand which is fluorescent and capable of generating cytotoxic singlet oxygen. Thus, this photochemical reaction facilitates the development of a novel anti-cancer treatment at the intersection of photodynamic therapy and photo-uncaging. Furthermore, light serves as a non-harmful external stimulus within a certain range of wavelengths (particularly infrared), allowing controlled spatiotemporal drug release, rendering the prodrug's mode of action highly targeted and promising. In this thesis, we apprehended the mechanism of the photoreaction by studying the effect of different physico-chemical experimental parameters. Also, we rationalized the influence of the nature of the leaving group on the efficiency of the double SNAr* on the quantum yield of the photoreaction. Then, we improved the design of the prodrug for its biological application in order to 1) ensure treatment biocompatibility by triggering the photoreaction in the biological transparency window, 2) enhance prodrug cellular internalization, and 3) develop a combined therapy by associating multiple anticancer agents and implementing targeting strategies

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Costenaro, Edson Roberto. "Utilização de enecarbamatos endociclicos na sintese de azanucleosideos." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249883.

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Orientador: Carlos Roque Duarte Correia
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica
Made available in DSpace on 2018-08-06T11:34:39Z (GMT). No. of bitstreams: 1 Costenaro_EdsonRoberto_D.pdf: 7691338 bytes, checksum: dba4657688a017bd010305e85e0d8f8d (MD5) Previous issue date: 2005
Resumo: Nos últimos anos existe um grande interesse na obtenção de nucleosídeos e derivados estruturalmente relacionados em virtude do amplo espectro de atividades biológicas apresentadas por essa classe de compostos. Diversos tipos de análogos apresentando as mais diversas alterações estruturais têm sido relatados, entre os quais os azanucleosídeos, onde o átomo de oxigênio da porção glicosídica é substituído por um átomo de nitrogênio. Na primeira parte deste trabalho vários enecarbamatos endocíclicos quirais de cinco membros, enantiomericamente puros (CG-quiral), foram obtidos em uma seqüência de sete etapas a partir do ácido L-glutâmico e utilizados na síntese de azanucleosídeos. Na segunda parte deste trabalho utilizou-se a adição eletrofílica de brometo de fenilselenenila à enecarbamatos endocíclicos como etapa chave na obtenção de uma série de N-azanucleosídeos inéditos (estruturalmente relacionados às drogas atualmente utilizadas no coquetel anti-HIV). Na última parte deste trabalho, durante um estudo que avaliou os fatores que determinam a diastereosseletividade facial na arilação de Heck de enecarbamatos endocíclicos com sais de diazônio, foi desenvolvida a síntese total e estereosseletiva do C-azanucleosídeo de Schramm (uma pirrolidina sintética com potente atividade tripanocida). Este estudo ilustra a versatilidade de enecarbamatos endocíclicos como intermediários sintéticos na construção de moléculas mais complexas
Abstract: There was a great interest in the preparation of nucleosides and derivatives in the last years due to the large spectrum of biological activities of these substances. Several analoges with structural modifications have been reported in the literature, such as azanucleosides, where the oxigen atom of the glicosidic portion is replaced by a nitrogen. In the first part of this work, several five membered ring endocyclic enecarbamates, that are enantiomerically pure (chiral-GC), were obtained in seven steps sequence from L-glutamic acid and used in the synthesis of azanucleosides. In the second part of this work, the eletrophilic addition of phenylselenenyl bromide to endocyclic enecarbamates was used as the key step in synthesis of a unpublished series of N-azanucleosides (structurally related to the drugs presents in the anti-HIV cocktail). In the last step of this work, during a study to determinate the factors that command the facial diastereoselectivity on the Heck arylation of endocyclic enecarbamates with diazonium salts, a total and stereoselective synthesis of Schramm C-azanucleoside (a synthetic pyrrolidine with potent tripanocidal activity) was performed. These studies have show the versatility of endocyclic enecarbamates as synthetic intermediates to the building of more complex molecules
Doutorado
Quimica Organica
Doutor em Ciências

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Valiulytė, Giedrė. "Azodažiklių sintezė iš aromatinių aminų diazonio druskų." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140630_134139-62079.

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Darbo tikslas: dviem metodais gauti azodažiklius iš aromatinių aminų diazonio druskų, nustatyti jų pKa reikšmes, įvertinti spektrines savybes bei pritaikyti kaip indikatorius. Darbo uždaviniai: Gauti azodažiklius iš metilanilinų ir 4-nitroanilino vykdant jų diazonio druskų hidrolizę arba jungiant su 1-naftoliu bei 2-naftoliu, apskaičiuoti gautų junginių išeigas, nustatyti jų pKa reikšmes, spektrines savybes, galimą kaip indikatorių pritaikymą. Metodai: Tyrimui atlikti naudojami du azodažiklių sintezės metodai. Apskaičiuotos abiem metodais gautų azodažiklių procentinės išeigos. ESC įvertintas junginių grynumas. Gautų azodažiklių pKa reikšmės bei pH ribos, kuriose keičiasi jų spalva, vertinamos atliekant potenciometrinį titravimą. Vandeniniai azodažiklių tirpalai vertinti spektrofotometriškai, matuojant tirpalų absorbcijos maksimumus ir optinius tankius. Rezultatai: Azodažikliai, atliekant aromatinių aminų diazonio druskų hidrolizę (hidrolizatas sudarytas iš 44 ml vandens ir 20 ml koncentruotos H2SO4), gaunami veikiant aminus koncentruota HCl, kai hidrolizato temperatūra pakeliama iki 104-110 oC. Atliekant tradicinę azodažiklių sintezę išeigos yra geros-labai geros (vidutinė išeiga yra 76,95 proc.), o vykdant diazonio druskų hidrolizę – vidutinės (junginiai gaunami su vidutine 41,44 proc. išeiga). Tradiciniu metodu gautų naftolinių azodažiklių pKa reikšmės yra 8,8-11,0 ribose, o fenolinių, gautų atliekant eksperimentinę sintezę, - 7,5 8,0. Spektrofotometrinis tyrimas parodė... [toliau žr. visą tekstą]
Aim of the work: synthesis of azo dyes from aromatic amines diazonium salts by two methods, determination of their pKa values, spectral features and applicability as indicators of produced azo dyes. Main objectives: to obtain azo dyes from methylanilines and 4-nitroaniline by hydrolysis of their diazonium salts or by binding with 1-naphtol and 2-naphtol, to calculate yields of obtained compounds, to determine their pKa values, spectral features and their possible application as indicators. Methods: Two methods of azo dyes synthesis are used to perform the assay. Percentage yields of synthesized compounds, obtained by both methods, are calculated. Purity of compounds is evaluated by HPLC. pKa values and range of pH where the colour changes of received compounds are evaluated by potentiometric titration. Aqueous solutions of azo dyes are assessed by measuring absorption peaks and optical densities with a spectrophotometer. Results: it is necessary to synthesise aromatic amines diazonium salts with conc. HCl and to perform hydrolysis in 104-110 oC temperature when hydrolysate consist of 44 ml water and 20 ml conc. H2SO4 in order to obtain azo dyes by experimental method. Yields of traditional method are good-very good (average yield is 76,95 proc.), yields of experimental method are moderate (average yield is 41,44 proc.). pKa values of naphtolic azo dyes which are obtained by traditional method are 8,8-11,0 and phenolic azo dyes – 7,5-8,0. Spectrophotometric studies showed that... [to full text]

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Ahmed, Nihad Kamal Ibrahim. "A novel electrochemical platform based on screen printed carbon electrodes (SPCEs) for molecular diagnostics." Doctoral thesis, Universitat Rovira i Virgili, 2020. http://hdl.handle.net/10803/669466.

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L’objectiu d’aquest treball és desenvolupar dispositius de diagnòstic molecular electroquímics de baix cost basats en microsistemes d’elèctrodes serigrafiats. Aquesta tesi es centra en mètodes per incrementar la reproduibilitat i la fiabilitat d’assajos moleculars emprant aquest tipus d’elèctrodes. Per desenvolupar el concepte es va utilitzar com a model a detectar Karlodinium armíger, una alga tòxica. Es va escollir el mètode d’amplificació isotèrmic: Recombinase Polymerase Amplification (RPA) ja que pot ser incorporat fàcilment en dispositius portàtils d’anàlisis. El principal problema dels elèctrodes serigrafiats rau en les interaccions no específiques que ocorren amb els porus i la superfície irregular dels elèctrodes, cosa que afecta la fiabilitat dels resultats. Per solucionar aquest problema, proposem dos mètodes: al primer mètode, una sal carboxilada de diazoni va ser electrodepositada i posteriorment modificada covalentment amb una sonda d’ADN aminada, formant una capa de reconeixement a la superfície del SPCE. Amb aquesta metodologia es van aconseguir la hibridació i la detecció de les mostres d’ADN amplificades per RPA en estat sòlid i líquid, obtenint límits de detecció de 0,1fM i 0,3fM, respectivament. Tot i així, aquest mètode requereix reaccions químiques en solució i l’activació electroquímica dels elèctrodes durant la fabricació, fet que incrementa la complexitat i el cost de la producció. Una millor alternativa per a la fabricació d’elèctrodes a gran escala és la modificació dels mateixos per deposició. Concretament, nosaltres hem introduït l’ús d’un polímer reticular de poli(L-lisina)
El objetivo de este trabajo es desarrollar dispositivos de diagnóstico molecular electroquímico de bajo coste basados en microsistemas de electrodos serigrafiados. Esta tesis se centra en métodos que incrementen la reproducibilidad y la fiabilidad de ensayos moleculares utilizando este tipo de electrodos. Para desarrollar el concepto se usó como modelo a detectar Karlodinium armiger, un alga tóxica. Se escogió el método isotérmico de amplificación: Recombinase Polymerase Amplification (RPA) ya que puede ser incorporado fácilmente en dispositivos portátiles de análisis. El principal problema de los electrodos serigrafiados reside en las interacciones no específicas que ocurren con los poros y la superficie irregular de los electrodos, cosa que puede afectar a la fiabilidad de los resultados. Para solucionar este problema, proponemos dos métodos: en el primer método una sal carboxilada de diazonio se electrodeposita i posteriormente se modifica covalentemente con una sonda de ADN carboxilada, formando una capa de reconocimiento en la superficie del SPCE. Con esta metodología se consiguió la hibridación i detección de muestras de ADN amplificadas por RPA en estado sólido i líquido, obteniendo límites de detección de 0,1fM i 0,3fM respectivamente. Aun así, este método requiere de reacciones química en solución y la activación electroquímica de los electrodos durante la fabricación, hecho que incrementa la complejidad y el coste de producción. Una mejor alternativa para la fabricación de electrodos a gran escala consiste en la modificación de estos por deposición.
The objective is to develop an electrochemical platform based on screen printed microsystems that enable low cost, point of use molecular diagnostics. This thesis focuses on methods to increase the reliability and reproducibility of screen printed electrode-based molecular assays. As proof of concept Karlodinium armiger, a toxic microalgae used as target. Recombinase Polymerase Amplification (RPA), an isothermal amplification method, was chosen because it can be easily incorporated in portable, point-of-use devices. Non-specific interactions with the porous and irregular surface of the SPCEs affect the reliability of the results. We demonstrate two methods can solve these problems: the first approach electro-grafted carboxylated diazonium was linked covalently to the aminated DNA probes (recognition layer) on the SPCE surface. DNA hybridization and detection were achieved in both solid and liquid phase RPA achieving detection limits (LODs) of 0.1 fM and 0.3 fM respectively. This approach requires wet chemistry and electrochemical activation of the electrodes during manufacturing, complicating production and increasing its cost. Surface modification by drop casting is more appropriate for large scale production. Basically, the surface of SPCEs was modified with poly (L-Lysine) polymer crosslinked with polyethylene glycol diglycidyl ether (PEGDE) that attached the aminated DNA probes. Polyethylene glycol (PEG) used to block the non-specific adsorption of horseradish (HRP) labels that were used for detection

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Akwi, Faith Mary. "Scalable chemistry involving diazonium salts." Thesis, Nelson Mandela Metropolitan University, 2016. http://hdl.handle.net/10948/6909.

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Herein an alternative approach aimed at reducing the cost of numbering up technique as a scale up strategy for chemical processes from the laboratory bench top to the industry is explored. The effect of increasing channel size on the reaction conversion of the synthesis of azo compounds is investigated. This was achieved via a systematic investigative understanding of the synthesis in microreactors where a proof of concept study was performed to determine the optimum reaction parameters in azo coupling reactions involving couplers with aminated or hydroxylated groups in Little Things Factory-MS microreactors (Channel diameter: 1.0 mm) It was found that at slightly alkaline conditions (pH 8.55) and at a temperature of 25 °C, excellent conversions were attained in the azo coupling reaction of the diazonium salt solution of 2,4-dimethylaniline to 2-naphthol. On the other hand, the azo coupling reaction of the diazonium salt solution of p-nitroaniline to diphenylamine was found to thrive at a pH of 5.71 and at a temperature of 25 °C. Using, these optimized reaction parameters, the in-situ and reactive quench of diazonium salts in LTF-MS microreactors was investigated where it was found that at a flow rate of 0.2 ml/min, 0.03 ml/min and 0.07 ml/min of diazotizable amine & HCl, sodium nitrite and coupler solutions respectively, a conversion of 98% is achieved in approximately 2.4 minutes. A library of azo compounds was thus generated under these reaction conditions from couplers with aminated or hydroxylated aromatic aromatic systems. The scaled up synthesis of these compounds in a homemade PTFE tubing (ID 1.5 mm) reactor system was thereafter investigated and comparable conversions were observed. Capitalizing on the benefits of a large surface area and the short molecular diffusion distances observed in microreactors, in-situ phase transfer catalyzed azo coupling reaction of diphenylamine to p-nitroaniline was also explored. In this investigation a rapid and easy optimization protocol that yielded a 99%, 22% and 33% conversion of diphenylamine, carbazole and triphenylamine respectively in approximately 2.4 minutes using Chemtrix microreactors was established. On increasing the microreactor channel internal diameter in the scaled up synthesis approach, it was found that a 0.5 mm increase in channel internal diameter does result in lower reaction conversions.

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Schotten, Christiane. "Investigating multistep continuous flow processes using diazonium salts." Thesis, Cardiff University, 2018. http://orca.cf.ac.uk/113812/.

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This thesis describes the investigation of continuous flow processes that incorporate the generation and use of diazonium salts. In this manner, processes for the preparation of triazenes, indoles and acridones have been developed. Diazonium salts are potentially unstable and hazardous and have to be handled with care. The use of continuous flow processes enables the safe synthesis avoiding accumulation of large quantities. This is due to the possibility to intercept intermediates at a precise point in time within a closed system. Diazonium salts were prepared via in situ diazotization of anilines with isoamylnitrite. Triazenes were formed via the interception of diazonium salts with secondary amines. The process had to be carefully developed to avoid clogging and fouling of the reactor. 26 examples have been prepared. The thermal behavior of 13 triazenes has been compared to their corresponding tetrafluoroborate diazonium salts, which has shown they are significantly more stable. In addition, VT NMR analysis has been performed to explore restricted rotation around the triazene bond. Further developments have found that indoles can be prepared via reduction of diazonium salts to their corresponding hydrazine with ascorbic acid and subsequent Fischer indole reaction in a microwave reactor. The use of such a hybrid, machine assisted approach has enabled the formation of a library of indoles. In this manner, 33 examples have been synthesised including the drug Zolmitriptan and nine of its analogues. The formation of acridones from benzyne and anthranilates has been investigated. Benzyne was prepared via the thermal decomposition of benzenediazonium-2-carboxylate. The compound decomposes above ambient temperatures and is known to be explosive when dry. The formation of benzyne has been investigated using the Diels- Alder reaction with furan as a model reaction and then conditions were applied to a range of substrates to investigate the scope. Problems with solubility of starting materials, diazonium salts and products were encountered and partially solved through the screening of different solvents. Finally, an exothermic reaction was investigated under continuous flow reactions. Commercially available thermocouples and in line NMR analysis were used to facilitate process optimisation. The exothermic reaction explored was the reduction of TMSCF3 to TMSCF2H with NaBH4. The exotherm was monitored using external, commercially available thermocouples to realise the development of a safe reaction regime. The incorporation of in situ NMR measurements has allowed realtime assessment of reaction conversion as a correlation to the exotherm. With the combined monitoring approaches a safe scale up process has been established. A hybrid flow - batch approach was used to scale up the reaction and increase the space time yield compared to the previously reported batch reaction.

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Addo, Isaac D. "Diazonium 4-(trifluorovinyloxy) Perfluorobutanesulfonyl Benzenesulfonimide Zwitterionic Monomer Synthesis." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etd/3137.

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3-Diazonium- 4-(trifluorovinyloxy) - perfluorobutanesulfonyl benzenesulfonimide zwitterionic monomer (see figure 1) is proposed to be polymerized and further act as a new electrolyte for Polymer exchange membrane fuel cells (PEMFCs). One reason is that, the aromatic trifluorovinyl aryl ether (TFVE) group can easily be homopolymerized to aromatic perfluorocyclobutane (PFCB) polymer. Furthermore, the diazonium moiety in the monomer is expected to covalently attach the electrolyte to the carbon electrodes support. The perfluoroalkyl(aryl) sulfonimide (PFSI) pendant provides good chemical and mechanical stability as well as better proton conductivity. Several multi-step synthetic schemes are designed to obtain such monomer from perfluoroalkyl(aryl) sulfonimide (PFSI). Among them, the purified coupling product 4-OCF2CF2Br-3-NO2-PhSO2(M) SO2C4F9 from the first approach was successfully completed. The next stages of the work will involve dehalogenation, reduction, and diazotization to achieve the targeting monomer. All the intermediates were characterized by 1H and 19F NMR and FT-IR spectroscopy.

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Mesnage, Alice. "Diazonium salts induced anchoring process : mechanism, application(s)." Palaiseau, Ecole polytechnique, 2011. https://pastel.hal.science/docs/00/62/90/41/PDF/Manuscrit_Alice_Mesnage.pdf).

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In this work, three surface functionalization processes have been studied: the spontaneous grafting from diazonium salts, the chemically induced grafting from diazonium salts and the chemically induced grafting from diazonium salts in presence of vinylic monomers (which is Graftfast). These processes work at room temperature, atmospheric pressure, in aqueous medium and without any external energy source ("green" chemistry). They lead to the formation of organic films (in particular polymer films in the case of the Graftfast process), stable, strongly grafted and with a controlled thickness (chemically activated processes). Contrary to diazonium salt electrografting methods, the reaction can occur on any type of substrate from insulators to conductors including nanomaterials. The so modified surface can show new properties (for instance water-repellency or protection against corrosion) which is of a major interest in some industrial fields. The main objective of this work was to understand the grafting mechanism of those processes, especially of the Graftfast process, by studying the chemical composition of the films, their structure as well as the composition of the reactive solution. As for classical radical chain polymerization, the mechanism can be split in three steps: initiation, propagation, termination. The polymerization is initiated by aryl radicals in solution coming from the chemical reduction of the diazonium salts (outer sphere or inner sphere mechanism according to the reducing agent used). In parallel, aryl radicals can graft to the surface of the substrate and form an essential polyphenylene primer layer. The propagation stops when the growing polymer chains react on the aromatic rings already grafted on the substrate (termination step). It results an aryl groups/polymers mixed structure of the films. The Graftfast process has been notably tested with a view to improve the dispersion of nano objects in water in the framework of a preliminary study on sunscreens containing TiO2 nanoparticles
Au cours de ce travail, trois procédés de fonctionnalisation de surface à partir de sels de diazonium ont été étudiés, à savoir : un procédé spontané, un procédé activé chimiquement et le procédé appelé Graftfast (activation chimique en présence de monomères vinyliques). Ces procédés, dits de chimie verte, fonctionnent à température ambiante, pression atmosphérique, en milieu aqueux et sans apport extérieur d'énergie. Ils conduisent à la formation de films organiques (notamment de polymères dans le cas du procédé Graftfast) stables, greffés de manière covalente et d'épaisseur contrôlée (procédés activés chimiquement). Contrairement aux méthodes d'électrogreffage de sels de diazonium, ces procédés peuvent s'appliquer à tout type de substrats allant des isolants aux conducteurs en passant par les nanomatériaux. Le substrat ainsi modifié peut présenter de nouvelles propriétés (par exemple d'hydrophilie, de protection contre la corrosion,. . . ) ce qui est d'un intérêt majeur dans certaines problématiques industrielles. L'objectif majeur de ce travail a été de comprendre les mécanismes réactionnels de ces trois procédés et plus particulièrement du procédé Graftfast en étudiant la composition chimique des films, leur structure mais aussi la composition des solutions réactionnelles. Comme pour une polymérisation radicalaire en chaîne conventionnelle, le mécanisme réactionnel du procédé Graftfast (cas le plus complexe) procède en trois étapes : amorçage, propagation, terminaison. La polymérisation est amorcée par les radicaux aryles en solution, issus de la réduction chimique des sels d'aryldiazonium (mécanisme en sphère interne ou en sphère externe selon le réducteur chimique). Parallèlement, les radicaux aryles peuvent se greffer à la surface du substrat et former une sous couche d'accroche de polyphenylene jouant un rôle essentiel dans la construction des films. La propagation s'achève lorsque les chaînes polymères en croissance réagissent par des réactions de transfert sur les noyaux aromatiques déjà greffés sur le substrat (étape de terminaison). Les films obtenus sont alors de structure mixte : groupements aryles, polymères. Ce procédé a notamment été testé dans le but d'améliorer la dispersion des nano-objets dans l'eau, dans le cadre d'une étude préliminaire sur les crèmes solaires à base de nanoparticules de dioxyde de titane

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Jones, Jason Robert. "Mechanism, catalysis and control in aromatic diazonium ion chemistry." Thesis, University of York, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306605.

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Salmi, Zakaria. "Surface, Sels de diazonium et Polymères : Synergie et Applications." Paris 7, 2013. http://www.theses.fr/2013PA077270.

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Le travail de cette thèse a été d'étudier la chimie de surface des sels de diazonium sur différente surface (ITO, nanotubes de carbone, argiles et diamant) et de greffer sur ces surface! un polymère par la méthode dite de « grafting onto » ou de « grafting from ». La première consiste à greffer un agent de couplage sur la surface et de faire réagir un polymère préformé avec une fonction réactive. En l'occurrence nous avons utilisé la chimie des diazoniums pour greffer une fonction alcyne sur une surface de nanotubes de carbone ensuite nous avons fais ces NTCs avec un polymère portant une fonction antagoniste (azide). La deuxième, repose sur le greffage d'un amorceur de polymérisation puis la croissance d'une chaîne polymère à partir de cette surface. En particulier nous avons greffé un amorceur de photopolymérisation sur des surfaces d'argiles d'ITO et de diamant puis fais croitre respectivement un polyglycidyl methacrylate, un polymère à empreinte moléculaire, et un polyhydroxyethyl methacrylate
The work of this Phd consist in the study of surface chemistry of diazonium sait on different surfaces (ITO, carbon nanotubes, clays, and diamond) and to graft on those surfaces a polymer by the "grafting onto" or the "grafting from" method. The first method involves grafting a coupling agent on the surface and makes react a polymer terminated with end functionality. Namely we used the diazonium chemistry to graft an alkyne functionality on carbon nanotubes then make react a polymer with an antagonist end functionality (azide). The second method is based on the grafting of an initiator then the growth of a polymer chain from this surface. In particular we graft a photopolymerisation initiator on clays, ITO and diamond surfaces. Then we polymerized respectively polyglycidyl methacrylate, a molecular imprinted polymer and a polyhyroxyethyl methacrylate

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Книги з теми "Diazonia"

Chehimi, Mohamed Mehdi, ed. Aryl Diazonium Salts. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.

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Chehimi, Mohamed M., Jean Pinson, and Fatima Mousli, eds. Aryl Diazonium Salts and Related Compounds. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04398-7.

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Patai, Saul. Chemistry of Diazonium and Diazo Groups. Wiley & Sons, Limited, John, 2010.

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Patai, Saul. Chemistry of Diazonium and Diazo Groups. Wiley & Sons, Limited, John, 2010.

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Patai, Saul. Patai Chemistry of Diazonium and Diazo Groups. Wiley & Sons, Limited, John, 2009.

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Patai, Saul. Patai Chemistry of Diazonium and Diazo Groups. Wiley & Sons, Limited, John, 2009.

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Aryl Diazonium Salts and Related Compounds: Surface Chemistry and Applications. Springer International Publishing AG, 2023.

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Mousli, Fatima, Mohamed Mehdi Chehimi, and Jean Pinson. Aryl Diazonium Salts and Related Compounds: Surface Chemistry and Applications. Springer International Publishing AG, 2022.

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Chehimi, Mohamed Mehdi. Aryl Diazonium Salts: New Coupling Agents in Polymer and Surface Science. Wiley & Sons, Incorporated, John, 2012.

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Banert, K., R. A. Aitken, K. M. Aitken, H. U. Reissig, B. Dugovicč, R. Zimmer, U. Jahn, et al. Nitro, Nitroso, Azo, Azoxy, and Diazonium Compounds, Azides, Triazenes, and Tetrazenes. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-041-00000.

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Частини книг з теми "Diazonia"

Norman, Richard, and James M. Coxon. "Aromatic diazonium salts." In Principles of Organic Synthesis, 409–28. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2166-8_13.

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Lane, J. D., C. J. Pickett, and D. R. Stanley. "From Diazonium Salts." In Inorganic Reactions and Methods, 109–10. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145227.ch80.

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Wardell, J. L. "With Diazonium Salts." In Inorganic Reactions and Methods, 320–23. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145258.ch90.

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McCreery, Richard, and Adam Johan Bergren. "Diazonium Compounds in Molecular Electronics." In Aryl Diazonium Salts, 219–39. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch10.

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Lee, W. D. "By Decomposition of Diazonium Salts." In Inorganic Reactions and Methods, 424. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145173.ch292.

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Pinson, Jean. "Attachment of Organic Layers to Materials Surfaces by Reduction of Diazonium Salts." In Aryl Diazonium Salts, 1–35. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch1.

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Rappich, Jörg, Xin Zhang, and Karsten Hinrichs. "Electronic Properties of Si Surfaces Modified by Aryl Diazonium Compounds." In Aryl Diazonium Salts, 241–53. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch11.

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Podvorica, Fetah I. "Non-Diazonium Organic and Organometallic Coupling Agents for Surface Modification." In Aryl Diazonium Salts, 255–81. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch12.

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Aswal, Dinesh K., Shankar Prasad Koiry, and Shiv Kumar Gupta. "Various Electrochemical Strategies for Grafting Electronic Functional Molecules to Silicon." In Aryl Diazonium Salts, 283–307. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch13.

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Belmont, James A., Christophe Bureau, Mohamed M. Chehimi, Sarra Gam-Derouich, and Jean Pinson. "Patents and Industrial Applications of Aryl Diazonium Salts and Other Coupling Agents." In Aryl Diazonium Salts, 309–21. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527650446.ch14.

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Тези доповідей конференцій з теми "Diazonia"

Uchino, Shou-ichi, Takao Iwayanagi, and Michiaki Hashimoto. "Photobleachable Diazonium Salt-Phenolic Resin Two-Layer Resist System." In 1988 Microlithography Conferences, edited by Scott A. MacDonald. SPIE, 1988. http://dx.doi.org/10.1117/12.968307.

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Uchino, Shou-ichi, Takao Iwayanagi, Takumi Ueno, Michiaki Hashimoto, and Saburo Nonogaki. "A Novel, Diazonium-Phenolic Resin Two-Layer Resist System Utilizing Photoinduced Interfacial Insolubilization." In Microlithography Conference, edited by Murrae J. Bowden. SPIE, 1987. http://dx.doi.org/10.1117/12.940302.

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Yuliandari, Pratiwi, Rahmat Wibowo, and Dita A. Nurani. "Para-carboxyphenyl diazonium - modified carbon paste electrode for analysis Cu (II) in water." In 4TH INTERNATIONAL SEMINAR ON CHEMISTRY. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0052020.

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Gui, Alicia L., Muthukumar Chockalingam, and J. Justin Gooding. "Modifying gold with 4-(trimethylammonio)-phenyl by aryl diazonium salts via reductive deposition." In 2010 International Conference on Nanoscience and Nanotechnology (ICONN). IEEE, 2010. http://dx.doi.org/10.1109/iconn.2010.6045200.

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PICCOLI, María Belén, Raquel Viviana VICO, and Nancy Fabiana FERREYRA. "ELECTROCHEMICAL CHARACTERIZATION OF GLASSY CARBON ELECTRODES MODIFIED WITH SWCNT FUNCTIONALIZED WITH DIAZONIUM SALT." In SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 2021 INTERNATIONAL VIRTUAL CONFERENCE. DR. D. SCIENTIFIC CONSULTING, 2022. http://dx.doi.org/10.48141/sbjchem.21scon.08_abstract_ferreyra.pdf.

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Although carbon nanotubes have unique properties, one of the biggest drawbacks in practice is the difficulty in forming dispersions of individual nanotubes in a given solvent. Covalent functionalization of carbon nanotubes allows the incorporation of chemical groups at the nanotube surface that, according to its polarity, facilitates the dispersibility in different solvents. In this work, singled-wall carbon nanotubes were functionalized by spontaneous grafting with a diazonium salt obtained from the 4-aminobenzoic acid to obtain SWCNT-pB. The nanomaterial obtained was characterized by several methodologies that the covalent incorporation of the functional groups. SWCNT-pB were dispersed in ethanol/water 50% V/V under ultrasonic treatment, and the exfoliation degree was evaluated by UV-Vis spectrophotometry. under optimal conditions, SWCNT-pB dispersion was stable for more than 45 days. Glassy carbon electrodes (GCE) modified with the nanomaterial show significant increases in their capacitive current and a faradaic process due to redox species confined on the surface of SWCNT-pB whose anodic peak currents depend linearly with the scan rate. The modified electrodes also show a catalytic response towards ascorbic acid (AA) and notorious increments in the oxidation and reduction currents of H2O2. The stability of the dispersions and the excellent electrochemical responses obtained make this nanomaterial very interesting for its application in electrochemical detection.

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Sakurai, Ikuo, Masaaki Todoko, and Masazumi Hasegawa. "Submicron Optical Lithography Using Contrast Enhanced Material With Diazonium Salt As A Photobleachable Material." In 1988 Microlithography Conferences, edited by Scott A. MacDonald. SPIE, 1988. http://dx.doi.org/10.1117/12.968323.

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Estevam, Idália, Emmanuelle Silva, and Lothar Bieber. "Synthesis of allyl e alkylarenes by Barbier alkylation of diazonium salts in aqueous medium." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0261-2.

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Звіти організацій з теми "Diazonia"

Wheeler, David. Diazonium Molecules onto Metallic Surface. Office of Scientific and Technical Information (OSTI), March 2015. http://dx.doi.org/10.2172/1173146.

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