Добірка наукової літератури з теми "Coronary heart disease"

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Статті в журналах з теми "Coronary heart disease"

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Nurmamadovna, Ishankulova Nasiba. "Coronary Heart Disease." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 02 (February 28, 2021): 31–36. http://dx.doi.org/10.37547/tajmspr/volume03issue02-04.

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The article covers the etiology, pathogenesis, classification, diagnosis, clinical picture and treatment of coronary heart disease, provides a literature review. Cardiovascular disease (CVD) represents the leading cause of death among women as well as men. The number of deaths due to CVD in women are greater than in men. There are significant gender-related differences concerning CVD.
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Shakhnoza, Iskandarova, and Amilova Asalya. "PREVENTION OF CORONARY HEART DISEASE." American Journal of Medical Sciences and Pharmaceutical Research 04, no. 04 (April 1, 2022): 19–21. http://dx.doi.org/10.37547/tajmspr/volume04issue04-05.

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Primary prevention, based on healthy lifestyle habits that prevent the emergence of risk factors, is the preferred method of reducing cardiovascular risk. Reducing the prevalence of obesity is the most urgent task, and it is pleiotropic in that it affects blood pressure, lipid profile, glucose metabolism, inflammation, progression of atherothrombotic disease. Physical activity also improves several risk factors, with the added potential to lower heart rate.
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Sudhakar, B. G. K. "Structural heart disease interventions." Clinical Research and Clinical Trials 3, no. 5 (June 25, 2021): 01–05. http://dx.doi.org/10.31579/2693-4779/042.

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Seed for invasive cardiology was sown in early part of nineties. Cardiac catheterization was actually pioneered by Werner Forssmann in 1929. However, credit for therapeutic interventional cardiology should go to US vascular radiologist, Charles Theodore Dotter for performing first peripheral arterial angioplasty [PTA] in 1964. Subsequently, a German cardiologist by name Andreas Gruentzig adapted the technique in 1974 to suit coronary artery disease and performed the first human coronary balloon angioplasty to treat blockage in coronary artery in 1977.
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Windecker, S. "CORONARY DISEASE: Intervention in coronary artery disease." Heart 83, no. 4 (April 1, 2000): 481–90. http://dx.doi.org/10.1136/heart.83.4.481.

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Gulnara, Asadova, and Djamalov Abdurakhman. "REMEDIES AND RECOMMENDATIONS CORONARY HEART DISEASES." Eurasian Journal of Medical and Natural Sciences 03, no. 02 (February 1, 2023): 224–28. http://dx.doi.org/10.37547/ejmns-v03-i02-p1-37.

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Prevention of coronary heart disease is a series of complex measures aimed at preventing the onset of the disease, the development and occurrence of possible (predictable) complications, which can be even fatal. Prevention of coronary heart disease is indicated for both sick people and healthy people who are at risk of developing the disease. Patients diagnosed with coronary heart disease are shown non-drug treatment, which is a complete or partial elimination of risk factors. Risk factors are any predisposing factors that increase the likelihood of developing or worsening a disease. Risk factors for coronary heart disease are fundamentally divided into removable and non-removable.
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Jha, Dr Sudha, Dr Naved Ahmad, Dr Surya Kant Nagtilak, and Dr Maheshwar Chawla. "Coronary Heart Disease, A Gift of Modern Civilization." International Journal of Scientific Research 2, no. 11 (June 1, 2012): 378–80. http://dx.doi.org/10.15373/22778179/nov2013/122.

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Timmis, A. "Coronary disease: Acute coronary syndromes: risk stratification." Heart 83, no. 2 (February 1, 2000): 241–46. http://dx.doi.org/10.1136/heart.83.2.241.

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Gulyabin, Konstantin Robertovich. "Coronary heart disease." Spravočnik vrača obŝej praktiki (Journal of Family Medicine), no. 1 (2022): 63–66. http://dx.doi.org/10.33920/med-10-2201-09.

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Coronary heart disease is of great clinical importance in medical practice. The development of medical science makes it possible to introduce new modern methods of treating this disease. One of these is coronary artery bypass grafting, a modern method of treating coronary heart disease, which allows to reliably increase myocardial perfusion and prolong the life expectancy of patients with coronary heart disease.
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Lavie, Carl J., Gary Legwold, and Michael E. DeBakey. "Coronary heart disease." Postgraduate Medicine 102, no. 2 (August 1997): 210–15. http://dx.doi.org/10.3810/pgm.1997.08.285.

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Williams, Samantha. "Coronary heart disease." Nursing Standard 19, no. 51 (August 31, 2005): 67–68. http://dx.doi.org/10.7748/ns.19.51.67.s58.

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Дисертації з теми "Coronary heart disease"

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Brouilette, Scott Wayne. "Telomeres and coronary heart disease." Thesis, University of Leicester, 2004. http://hdl.handle.net/2381/29899.

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Using mean telomere length as a marker of biological age, I show that: 1. Subjects with premature myocardial infarction (MI) have significantly shorter telomeres than age-sex matched, healthy, controls. The mean telomere length in MI subjects was similar to controls almost 11 years older. 2. Healthy young adult children of families with a strong history of premature MI have shorter telomeres than age matched children of families without such a history. 3. Shorter telomere lengths are associated with increase risk of subsequent CHD events in a prospective study. This analysis was carried out on samples collected in the West of Scotland Coronary Prevention Study (WOSCOPS). This randomised blinded trial was designated to examine the benefits of statin treatment on preventing CHD and showed a 30% reduction of events in those treated with pravastatin. Interestingly, my analysis showed that this benefit of statin is only seen in those subjects at higher risk of CHD based on their telomere length.;As the final part of the thesis I carried out a quantitative linkage trait (QTL) analysis in sib-pairs in an attempt to identify genetic loci regulating telomere length. I report the mapping of a major QTL on chromosome 12 that determines almost 50% of the inter-individual variation in mean telomere length.;These findings support a novel "telomere" hypothesis of CHD. They indicate that telomere biology is intimately linked to the genetic aetiology and pathogenesis of CHD. Specifically, the findings suggest that (i) those individuals born with shorter telomeres may be at increased risk of CHD (ii) rather than individual genes, a more global structural property of the genetic material may explain the familial basis of CHD (iii) variation in telomere length may explain, in part, the variable age of onset of CHD. The findings provide several new avenues for future research.
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Lee, Chi-hang. "Microvascular obstruction following percutaneous coronary intervention for coronary artery disease." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43278723.

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Heiser, Claire Anne. "Personality predictors of coronary heart disease." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/50027.

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Fifty percent of the diagnosed cases of coronary heart disease in the United States are of unknown etiology. This study proposed that five personality traits— achievement, dominance, aggression, succorance and Critical Parent—differentiate individuals with coronary heart disease manifestations. The ultimate goal of this research was to formulate a predictive profile of at-risk individuals of developing coronary heart disease. Cardiac rehabilitation units' participants from across the United States were recruited as subjects. Randomly selected cardiac rehabilitation units were sent an initial letter inquiring whether their staff would be willing to participate in the study by administering the instruments to their participants. Eight units from each of the 50 states were contacted. A total of fourteen units agreed to participate. One hundred sixty-nine subjects completed the Demographic Data Questionnaire and the Adjective Check List. Five scale scores, representing the five personality differentials, were analyzed. Comparison of the male subject population (n=135) and the male normative population (n=198) revealed no significant differences in terms of the five traits. Comparison of diagnostic subgroups of the subject population also revealed no significant differences. It was concluded that the subject population did not differ significantly from the normative population in terms of the five traits assess by the instrument used. The goal of a predictive profile was not realized due to this lack of findings.
Master of Science
incomplete_metadata
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Lee, Chi-hang, and 李志恆. "Microvascular obstruction following percutaneous coronary interventionfor coronary artery disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43278723.

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Danesh, John. "Chronic infection and coronary heart disease." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326020.

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Kounali, Daphne. "Early growth and coronary heart disease." Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436926.

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Zapanta, Laurence (Laurence F. ). "Heart rate variability in mice with coronary heart disease." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/34118.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.
Includes bibliographical references (leaves 69-71).
Heart rate variability (HRV), the beat-to-beat fluctuation of the heart rate, is a non-invasive test that measures the autonomic regulation of the heart. Assessment of HRV has been shown to predict the risk of mortality in patients after an acute myocardial infarction. Recently, the Krieger lab at MIT developed genetically engineered double knockout (dKO) mice that develop coronary artery disease accompanied by spontaneous myocardial infarctions and die at a very young age. This thesis investigated whether HRV could function as a prognostic indicator in the dKO mouse. A novel method for estimating physiological state of the mouse from the electrocardiogram using an innovative activity index was developed in order to compare HRV variables at different times while controlling for physiologic state. Traditional time and frequency domain variables were used to assess the prognostic power of HRV. Results have shown that none of the HRV variables were helpful in predicting mortality in the dKO mice. Mean heart rate showed some prognostic power, but it was not consistent in all the dKO mice. Finally, the activity index developed in this thesis provided a reliable metric for activity in mice as validated by a camera with motion detection.
by Laurence Zapanta.
S.M.
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Rose, Edward Leslie. "Coronary heart disease in patients with peripheral vascular disease." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305544.

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Bagés, Nuri. "Psychosocial risk factors and coronary heart disease." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 2000. http://arno.unimaas.nl/show.cgi?fid=6899.

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Chandola, Tarani. "Social inequality in coronary heart disease outcomes." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285007.

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Книги з теми "Coronary heart disease"

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National Heart, Lung, andlood Institute, ed. Coronary heart disease. [Bethesda, Md.?]: U.S. Dept. of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, 2003.

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Vlodaver, Zeev, Robert F. Wilson, and Daniel J. Garry, eds. Coronary Heart Disease. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-1475-9.

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Sandler, Gerald, ed. Coronary Heart Disease. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-010-9218-0.

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Scottish Forum for Public Health Medicine., Scottish Needs Assessment Programme, and Special Needs Action Programme, eds. Coronary heart disease. Glasgow: Scottish Forum for Public Health Medicine, 1998.

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National Board for Nursing, Midwifery and Health Visiting for Scotland. Coronary heart disease. Edinburgh: The Board, 1998.

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National Dairy Council. Nutrition Service. Coronary heart disease. London: National Dairy Council, 1993.

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Royal Colleges of Physicians of the United Kingdom. Committee on Health Promotion. Coronary heart disease. London: Faculty of Community Medicine of the Royal Colleges of Physicians of the United Kingdom, 1988.

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Anne, Halliday, Ashwell Margaret, and British Nutrition Foundation, eds. Coronary heart disease. London: British Nutrition Foundation, 1992.

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1928-, Sandler Gerald, ed. Coronary heart disease. Lancaster: MTP Press, 1987.

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Petersen, Sophie. Coronary heart disease statistics. London: British Heart Foundation, 2002.

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Частини книг з теми "Coronary heart disease"

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Bergersen, Lisa, Susan Foerster, Audrey C. Marshall, and Jeffery Meadows. "Coronary Angiography." In Congenital Heart Disease, 143–50. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-77292-9_23.

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Whang, William. "Coronary Heart Disease." In Encyclopedia of Behavioral Medicine, 557–59. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_396.

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Whang, William. "Coronary Heart Disease." In Encyclopedia of Behavioral Medicine, 503–5. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_396.

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Gaff, Lisa. "Coronary heart disease." In Dietetic and Nutrition Case Studies, 146–49. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781119163411.ch38.

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Tsuboi, Hirohito, Katsunori Kondo, Hiroshi Kaneko, and Hiroko Yamamoto. "Coronary Heart Disease." In Social Determinants of Health in Non-communicable Diseases, 41–52. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-1831-7_5.

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Feuerstein, Michael, Elise E. Labbé, and Andrzej R. Kuczmierczyk. "Coronary Heart Disease." In Health Psychology, 317–80. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4899-0562-8_10.

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Gorog, Diana. "Coronary Heart Disease." In The Interventional Cardiology Training Manual, 1–11. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71635-0_1.

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Marie, Philippe, and Norma Whittaker. "Coronary Heart Disease." In Disorders and Interventions, 88–115. London: Macmillan Education UK, 2004. http://dx.doi.org/10.1007/978-0-230-21399-9_6.

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Whang, William. "Coronary Heart Disease." In Encyclopedia of Behavioral Medicine, 1–3. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4614-6439-6_396-2.

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Schenck-Gustafsson, Karin. "Coronary Heart Disease." In Handbook of Clinical Gender Medicine, 190–205. Basel: KARGER, 2012. http://dx.doi.org/10.1159/000336385.

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Тези доповідей конференцій з теми "Coronary heart disease"

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Riyaz, Lubna, Muheet Ahmed Butt, and Majid Zaman. "Ensemble Learning for Coronary Heart Disease Prediction." In 2022 International Conference on Intelligent Technologies (CONIT). IEEE, 2022. http://dx.doi.org/10.1109/conit55038.2022.9848292.

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Pareek, Vishakha, and R. K. Sharma. "Coronary heart disease detection from voice analysis." In 2016 IEEE Students' Conference on Electrical, Electronics and Computer Science (SCEECS). IEEE, 2016. http://dx.doi.org/10.1109/sceecs.2016.7509344.

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Lin, Shisong, Xiaodong Zhuang, Shiyun Huang, Yahui Liu, Linlin Shen, and Xinxue Liao. "Face Analysis for Coronary Heart Disease Diagnosis." In 2019 12th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI). IEEE, 2019. http://dx.doi.org/10.1109/cisp-bmei48845.2019.8966020.

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Mangathayaru, Nimmala, B. Padmaja Rani, V. Janaki, Lakshmi Sowmya Kotturi, Manasa Vallabhapurapu, and G. Vikas. "Heart Rate Variability for Predicting Coronary Heart Disease using Photoplethysmography." In 2020 Fourth International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud) (I-SMAC). IEEE, 2020. http://dx.doi.org/10.1109/i-smac49090.2020.9243316.

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Runjing, Zhou, and Li Keyang. "Fisher classifier in diagnosis of coronary heart disease." In 2011 4th International Congress on Image and Signal Processing (CISP). IEEE, 2011. http://dx.doi.org/10.1109/cisp.2011.6100787.

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Malik, Varun, Ruchi Mittal, Ajay Rana, Irfan Khan, Pankaj Singh, and Bashar Alam. "Coronary Heart Disease Prediction Using GKFCM with RNN." In 2023 6th International Conference on Contemporary Computing and Informatics (IC3I). IEEE, 2023. http://dx.doi.org/10.1109/ic3i59117.2023.10398020.

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Gonsalves, Amanda H., Fadi Thabtah, Rami Mustafa A. Mohammad, and Gurpreet Singh. "Prediction of Coronary Heart Disease using Machine Learning." In the 2019 3rd International Conference. New York, New York, USA: ACM Press, 2019. http://dx.doi.org/10.1145/3342999.3343015.

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Ni, Jinhao, and Guanghua Ren. "Statistical Analysis of Factors Influencing Coronary Heart Disease." In 2022 14th International Conference on Computer Research and Development (ICCRD). IEEE, 2022. http://dx.doi.org/10.1109/iccrd54409.2022.9730221.

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Shirazi, Badrosadat Nategholeslam, Shiva Naghsh, Ali Akbar Safavi, and Amir Sharafkhaneh. "Machine Learning-Based Prediction of Coronary Heart Disease." In 2023 9th International Conference on Control, Instrumentation and Automation (ICCIA). IEEE, 2023. http://dx.doi.org/10.1109/iccia61416.2023.10506325.

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Li Xia, Fu Yifei, Bai Jing, Tian xin, and Li Fangjie. "Complexity analysis on heart rate variability of coronary heart disease patients." In 2008 International Conference on Technology and Applications in Biomedicine (ITAB). IEEE, 2008. http://dx.doi.org/10.1109/itab.2008.4570590.

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Звіти організацій з теми "Coronary heart disease"

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Zhang, Ruizhe, and Qingya Xie. A meta-analysis of cholesteryl ester transfer protein(CETP) gene rs708272(G>A) polymorphism in association with cornoary heart disease risk. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2023. http://dx.doi.org/10.37766/inplasy2023.6.0021.

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Review question / Objective: To seek the association of the CETP rs708272 polymorphism with CHD.To figure out if the carriers of allele rs708272-A reduce or increase the risk of CHD in comparison with carriers of allele rs708272-G under allele model, dominant model and recessive model. Condition being studied: The inclusion criteria of CHD:(1)the presence of stenosis≥50% in a minimum of one main segment of coronary arteries (the right coronary artery, left circumfex, or left anterior descending arteries) by coronary angiography.(2) symptoms representing angina pectoris, electrocardiographic changes, and elevations of cardiac enzymes based on the criteria of the World Health Organization. (3) a certifed record of coronary artery bypass graft or percutaneous coronary intervention were included in the study.The exclusion criteria of CHD :patients with congenital heart disease, cardiomyopathy, and valvular disease.Controls:the same populations as the cases and specifed to be without CAD, cardiovascular and cerebrovascular diseases, and peripheral atherosclerotic arterial disease.
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Weng, JIeqiong, Jingfang Zhang, Ke Xu, Mengfei Yuan, Tingting Yao, Xinyu Wang, and Xiaoxu Shen. Efficacy of Shexiang Baoxin Pills Combined with Statins on Blood Lipid Profile in Patients with Coronary Heart Disease: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0100.

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Review question / Objective: P(Population) :Patients with coronary heart disease; I(Intervention) : Statins treatment in combination with Shexiang Baoxin pill; C(Comparison): Statins alone; O(Outcome): Improvement of symptoms and blood lipids; S(Study design):Clinical randomized trials. Eligibility criteria: To be included, trials were required to meet the following criteria: (1) patients were included in the studies according to diagnostic criteria of coronary heart disease established by the WHO, InternationalSociety of Cardiology and Association (ISCA), Internal Medicine, 7th edition ( IM-7th), Practice of InternalMedicine, 14th edition ( PIM-14th), Guidelines for the Diagnosis of Cardiovascular Diseases in InternalMedicine, 3rd edition (GIM-3rd) or conventional diagnostic criteria (CDC) including assessment of anginapectoris and electrocardiogram (ECG) results; (2) the study was conducted as a randomized controlled trial.
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Wang, Shuang, Aidong Liu, Zhilei Wang, and Yue Zhang. Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of angina pectoris of coronary heart disease: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0100.

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Review question / Objective: This study is the protocol for a systematic review to evaluate the Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of angina pectoris of coronary heart disease: a systematic review and meta-analysis. we conducted a systematic review and meta-analysis of published randomized clinical trials (RCTs) of such combined therapy in the treatment of angina pectoris of coronary heart disease, It provides a reliable scientific basis for clinicians to use this approach to treat angina pectoris of coronary heart disease. Information sources: We conducted a systematic search for relevant documents in the Chinese and English databases, and the search time is limited to November 23, 2021. The following eight databases are included : PubMed,EMBASE, Web of Science, The Cochrane Library, Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang Database.Relevant journals were searched to trace the references included in the study. Other resources will be searched if necessary.
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Wei, Dongmei, Yang Sun, and Hankang Hen. Effects of Baduanjin exercise on cardiac rehabilitation after percutaneous coronary intervention: A protocol for systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0080.

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Review question / Objective: Can Baduanjin exercise improve the cardiac rehabilitation of patients with coronary artery disease after percutaneous coronary artery surgery? Condition being studied: Coronary heart disease (CHD), also known as coronary artery disease (CAD), is the single most common cause of death globally, with 7.4 million deaths in 2013, accounting for one-third of all deaths (WHO 2014). PCI has been shown to be effective in reducing mortality in patients with CHD. During follow-up, it has been shown that the benefits of PCI can be offset by the significant risks of coronary spasm, endothelial cell injury, recurrent ischemia, and even restenosis or thrombus. Numerous guidelines endorse the necessity for cardiac rehabilitation (CR), which is recommended for patients with chronic stable angina, acute coronary syndrome and for patients following PCI. Baduanjin have been widely practised in China for centuries, and as they are considered to be low risk interventions, their use for the prevention of cardiovascular disease is now becoming more widespread. The ability of Baduanjin to promote clinically meaningful influences in patients with CHD after PCI, however, still remains unclear.
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Dong, Guoqi, Mengye Lu, Xiaoliang Wu, Hao Chen, Hongru Zhang, and Yihuang Gu. Network meta-analysis of Traditional Chinese medicines for depression in coronary heart disease patients. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2020. http://dx.doi.org/10.37766/inplasy2020.5.0036.

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Wienke, Andreas, Anne M. Herskind, Kaare Christensen, Axel Skytthe, and Anatoli I. Yashin. The influence of smoking and BMI on heritability in susceptibility to coronary heart disease. Rostock: Max Planck Institute for Demographic Research, January 2002. http://dx.doi.org/10.4054/mpidr-wp-2002-003.

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McCausland, Rachel, Joann Fontanarosa, and Ravi Patel. Nonemergent Percutaneous Coronary Intervention Versus Optimal Medical Treatment for Stable Ischemic Heart Disease: A Rapid Response Literature Review. Agency for Healthcare Research and Quality (AHRQ), August 2023. http://dx.doi.org/10.23970/ahrqepcrapidcoronary.

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Aims. There is uncertainty around the optimal role of percutaneous coronary intervention (PCI) for management of chronic coronary syndrome, specifically when patients have disease in multiple coronary vessels and disease in the proximal portion of the left anterior descending coronary artery. This uncertainty was reflected in 2021 guidance from the American College of Cardiology (ACC)/American Heart Association (AHA) on coronary artery revascularization. The Agency for Healthcare Research and Quality has commissioned this rapid response literature review to meet a Congressional request for a summary of recent evidence on the benefits of angioplasties conducted in nonemergency situations. Methods. This rapid response literature review on the comparative effectiveness of nonemergent PCI followed established best systematic review methods, modified to meet a shortened project timeframe. We searched PubMed®, Embase®, and the Trip© medical database from 2018 through April 2023 for systematic reviews (SRs), clinical practice guidelines, and randomized controlled trials, and summarized the evidence comparing PCI to optimal medical therapy (OMT) for stable ischemic heart disease (SIHD). Our primary outcomes of interest were major objective cardiovascular outcomes, including mortality, myocardial infarction, stroke, urgent revascularization, or composites of one or more of these hard clinical outcomes. Where available, we also abstracted patient reported outcomes (e.g., angina severity and quality of life [QoL]) from included studies. Findings. Key findings from nine SRs and one primary study include: • The body of evidence directly comparing PCI to OMT for SIHD has remained largely unchanged since the 2021 ACC/AHA guidance’s publication. • Most studies of revascularization for coronary artery disease do not focus on direct head-to-head comparisons of PCI versus OMT for SIHD but instead either (1) compare OMT to invasive revascularization (PCI and coronary artery bypass graft [CABG] combined cohort); (2) compare PCI to CABG; or (3) compare different PCI techniques. • Another factor that complicates comparison is that the meta-analyses often included data from CABG and PCI combined cohorts (e.g., the recent landmark ISCHEMIA trial) but reported the outcomes as PCI specific. • In the general SIHD population, our review did not find evidence to support survival benefit or effect on hard clinical outcomes when PCI is added to OMT. • Limited evidence indicates there may be a beneficial effect of PCI on angina symptoms and measures of QoL, but most systematic reviews focused on major objective cardiovascular outcomes and did not consider QoL or freedom from angina. • Both OMT and PCI have evolved significantly during the period of time in which the systematic reviews’ included studies were conducted. It is not clear how these changes may have affected the applicability of past studies to current practice. Conclusions. The evidence directly comparing PCI to OMT for SIHD has remained largely unchanged since publication of the 2021 ACC/AHA guidelines. More research is needed to verify the comparative effectiveness of nonemergent PCI compared to medical treatment for individuals with SIHD, and how the effectiveness varies by certain patient populations and clinical presentation.
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li, jixu, shengdong iao, pengpeng Liang, Jie Cui, and weimin Jiang. Meta-analysis of timing of IABP implantation for CABG in patients with coronary heart disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2023. http://dx.doi.org/10.37766/inplasy2023.8.0083.

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Alobaidi, Larsa. Exploring the Links Between Gut Bacteria-Related Metabolites, Coronary Artery Disease (CAD) Risk, and Heart Failure (HF). Ames (Iowa): Iowa State University, December 2023. http://dx.doi.org/10.31274/cc-20240624-703.

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Cai, Ruping, Yuli Xu, and Qiang Su. Meta-analysis of blood lipid reduction for patients with coronary heart disease by combination of pitavastatin and ezetimibe. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2021. http://dx.doi.org/10.37766/inplasy2021.5.0072.

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