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Добірка наукової літератури з теми "CBR AGENTS"

Автор: Grafiati

Опубліковано: 11 вересня 2023

Оновлено: 16 квітня 2024

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Статті в журналах з теми "CBR AGENTS"

Heras, Stella, Vicente Botti, and Vicente Julián. "Challenges for a CBR framework for argumentation in open MAS." Knowledge Engineering Review 24, no. 4 (December 2009): 327–52. http://dx.doi.org/10.1017/s0269888909990178.

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AbstractNowadays, Multi-Agent Systems (MAS) are broadening their applications to open environments, where heterogeneous agents could enter into the system, form agents’ organizations and interact. The high dynamism of open MAS gives rise to potential conflicts between agents and thus, to a need for a mechanism to reach agreements. Argumentation is a natural way of harmonizing conflicts of opinion that has been applied to many disciplines, such as Case-Based Reasoning (CBR) and MAS. Some approaches that apply CBR to manage argumentation in MAS have been proposed in the literature. These improve agents’ argumentation skills by allowing them to reason and learn from experiences. In this paper, we have reviewed these approaches and identified the current contributions of the CBR methodology in this area. As a result of this work, we have proposed several open issues that must be taken into consideration to develop a CBR framework that provides the agents of an open MAS with arguing and learning capabilities.

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Robertson, Gregory T., Eric J. Bonventre, Timothy B. Doyle, Qun Du, Leonard Duncan, Timothy W. Morris, Eric D. Roche, Dalai Yan, and A. Simon Lynch. "In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus." Antimicrobial Agents and Chemotherapy 52, no. 7 (July 2008): 2313–23. http://dx.doi.org/10.1128/aac.01649-07.

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ABSTRACT Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program directed toward the synthesis of rifamycins with a lower propensity to elicit resistance development, a series of compounds were prepared that covalently combine rifamycin and quinolone pharmacophores to form stable hybrid antibacterial agents. We describe mode-of-action studies with Staphylococcus aureus of CBR-2092, a novel hybrid that combines the rifamycin SV and 4H-4-oxo-quinolizine pharmacophores. In biochemical studies, CBR-2092 exhibited rifampin-like potency as an inhibitor of RNA polymerase, was an equipotent (balanced) inhibitor of DNA gyrase and DNA topoisomerase IV, and retained activity against a prevalent quinolone-resistant variant. Macromolecular biosynthesis studies confirmed that CBR-2092 has rifampin-like effects on RNA synthesis in rifampin-susceptible strains and quinolone-like effects on DNA synthesis in rifampin-resistant strains. Studies of mutant strains that exhibited reduced susceptibility to CBR-2092 further substantiated RNA polymerase as the primary cellular target of CBR-2092, with DNA gyrase and DNA topoisomerase IV being secondary and tertiary targets, respectively, in strains exhibiting preexisting rifampin resistance. In contrast to quinolone comparator agents, no strains with altered susceptibility to CBR-2092 were found to exhibit changes consistent with altered efflux properties. The combined data indicate that CBR-2092 may have potential utility in monotherapy for the treatment of persistent S. aureus infections.

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Navarro, M., S. Heras, V. Julián, and V. Botti. "Incorporating temporal-bounded CBR techniques in real-time agents." Expert Systems with Applications 38, no. 3 (March 2011): 2783–96. http://dx.doi.org/10.1016/j.eswa.2010.08.070.

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Aydin, Burc. "Global Characteristics of Chemical, Biological, and Radiological Poison Use in Terrorist Attacks." Prehospital and Disaster Medicine 35, no. 3 (April 2, 2020): 260–66. http://dx.doi.org/10.1017/s1049023x20000394.

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AbstractBackground:Chemical, biological, and radiological (CBR) terrorism continues to be a global threat. Studies examining global and historical toxicological characteristics of CBR terrorism are lacking.Methods:Global Terrorism Database (GTD) and RAND Database of Worldwide Terrorism Incidents (RDWTI) were searched for CBR terrorist attacks from 1970 through 2017. Events fulfilling terrorism and poisoning definitions were included. Variables of event date and location, event realization, poisonous agent type, poisoning agent, exposure route, targets, connected events, additional means of harm, disguise methods, poisonings, and casualties were analyzed along with time trends and data gaps.Results:A total of 446 events of CBR terrorism were included from all world regions. A trend for increased number of events over time was observed (R2 = 0.727; coefficient = 0.511). In these attacks, 4,093 people lost their lives and 31,903 were injured. Chemicals were the most commonly used type of poison (63.5%). The most commonly used poisonous agents were acids (12.3%), chlorine or chlorine compounds (11.2%), riot control agents (10.8%), cyanides (5.8%), and Bacillus anthracis (4.9%). Occurrence of poisoning was confirmed in 208 events (46.6%). Most common exposure routes were skin, mucosa, or eye (57.2%) and inhalation (47.5%). Poison was delivered with additional means of harm in 151 events (33.9%) and in a disguised way in 214 events (48.0%), respectively.Conclusions:This study showed that CBR terrorism is an on-going and increasingly recorded global threat involving diverse groups of poisons with additional harmful mechanisms and disguise. Industrial chemicals were used in chemical attacks. Vigilance and preparedness are needed for future CBR threats.

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Oltenfreiter, Ruth, Ludovicus Staelens, Soraya Labied, Veerle Kersemans, Francis Frankenne, Agnes Noël, Christophe Van de Wiele, and Guido Slegers. "Tryptophane-Based Biphenylsulfonamide Matrix Metalloproteinase Inhibitors as Tumor Imaging Agents." Cancer Biotherapy and Radiopharmaceuticals 20, no. 6 (December 2005): 639–47. http://dx.doi.org/10.1089/cbr.2005.20.639.

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Hosseinimehr, Seyed Jalal. "Potential Utility of Radioprotective Agents in the Practice of Nuclear Medicine." Cancer Biotherapy and Radiopharmaceuticals 24, no. 6 (December 2009): 723–31. http://dx.doi.org/10.1089/cbr.2009.0635.

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Rosebrough, S. F., and D. F. Hartley. "Isothiocyanate-Trigalactose: Application for Antibody-Targeted Delivery of Diagnostic and Therapeutic Agents." Cancer Biotherapy and Radiopharmaceuticals 15, no. 5 (October 2000): 507–15. http://dx.doi.org/10.1089/cbr.2000.15.507.

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Ahmed, Ishtiaq, Saif Ur Rehman, Shiva Shahmohamadnejad, Muhammad Anjum Zia, Muhammad Ahmad, Muhammad Muzammal Saeed, Zain Akram, Hafiz M. N. Iqbal, and Qingyou Liu. "Therapeutic Attributes of Endocannabinoid System against Neuro-Inflammatory Autoimmune Disorders." Molecules 26, no. 11 (June 3, 2021): 3389. http://dx.doi.org/10.3390/molecules26113389.

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In humans, various sites like cannabinoid receptors (CBR) having a binding affinity with cannabinoids are distributed on the surface of different cell types, where endocannabinoids (ECs) and derivatives of fatty acid can bind. The binding of these substance(s) triggers the activation of specific receptors required for various physiological functions, including pain sensation, memory, and appetite. The ECs and CBR perform multiple functions via the cannabinoid receptor 1 (CB1); cannabinoid receptor 2 (CB2), having a key effect in restraining neurotransmitters and the arrangement of cytokines. The role of cannabinoids in the immune system is illustrated because of their immunosuppressive characteristics. These characteristics include inhibition of leucocyte proliferation, T cells apoptosis, and induction of macrophages along with reduced pro-inflammatory cytokines secretion. The review seeks to discuss the functional relationship between the endocannabinoid system (ECS) and anti-tumor characteristics of cannabinoids in various cancers. The therapeutic potential of cannabinoids for cancer—both in vivo and in vitro clinical trials—has also been highlighted and reported to be effective in mice models in arthritis for the inflammation reduction, neuropathic pain, positive effect in multiple sclerosis and type-1 diabetes mellitus, and found beneficial for treating in various cancers. In human models, such studies are limited; thereby, further research is indispensable in this field to get a conclusive outcome. Therefore, in autoimmune disorders, therapeutic cannabinoids can serve as promising immunosuppressive and anti-fibrotic agents.

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Sharma, Rakesh Kumar, Sudha Rana, and Natarajan Gopalan. "Towards Protecting Critical National Assets and Preparedness for Response to Hazardous Chemical, Biological and Radiological Attacks." Defence Life Science Journal 4, no. 4 (October 21, 2019): 256–65. http://dx.doi.org/10.14429/dlsj.4.15134.

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Hazardous chemical, biological and radiological (CBR) materials are catching attention of unscrupulous actors for creating terror and havoc. Threat perception for use of such materials by terrorists and non-state actors for malicious purposes, is not imaginative but real and imminent in today’s context. World has witnessed a number of such incidences in the recent years, e.g., Mustard gas attack against Kurdish forces in Iraq; ricin laced letters sent to US President and others senators; use of Nerve gas agents in Syria; capturing of Uranium from University of al- Mousal, Iraq by IS, etc. National assets like critical buildings where main legislative, historical building, Hospitals are some of the likely targets for CBR attacks attract quick coverage by media. Authorities related with managing and safeguarding mechanisms of the facilities to prevent such events happening also to enhance their capabilities as well as effective response. Essential CBR security should include measures to rapidly detect and effectively deter the CBR incidences their deleterious consequences. In this review, protection of the critical facilities from CBR attacks and capacity in terms of infrastructure, specialised training and mutual aid have been discussed.

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Robertson, Gregory T., Timothy B. Doyle, Qun Du, Leonard Duncan, Khisimuzi E. Mdluli, and A. Simon Lynch. "A Novel Indole Compound That Inhibits Pseudomonas aeruginosa Growth by Targeting MreB Is a Substrate for MexAB-OprM." Journal of Bacteriology 189, no. 19 (July 20, 2007): 6870–81. http://dx.doi.org/10.1128/jb.00805-07.

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ABSTRACT Drug efflux systems contribute to the intrinsic resistance of Pseudomonas aeruginosa to many antibiotics and biocides and hamper research focused on the discovery and development of new antimicrobial agents targeted against this important opportunistic pathogen. Using a P. aeruginosa PAO1 derivative bearing deletions of opmH, encoding an outer membrane channel for efflux substrates, and four efflux pumps belonging to the resistance nodulation/cell division class including mexAB-oprM, we identified a small-molecule indole-class compound (CBR-4830) that is inhibitory to growth of this efflux-compromised strain. Genetic studies established MexAB-OprM as the principal pump for CBR-4830 and revealed MreB, a prokaryotic actin homolog, as the proximal cellular target of CBR-4830. Additional studies establish MreB as an essential protein in P. aeruginosa, and efflux-compromised strains treated with CBR-4830 transition to coccoid shape, consistent with MreB inhibition or depletion. Resistance genetics further suggest that CBR-4830 interacts with the putative ATP-binding pocket in MreB and demonstrate significant cross-resistance with A22, a structurally unrelated compound that has been shown to promote rapid dispersion of MreB filaments in vivo. Interestingly, however, ATP-dependent polymerization of purified recombinant P. aeruginosa MreB is blocked in vitro in a dose-dependent manner by CBR-4830 but not by A22. Neither compound exhibits significant inhibitory activity against mutant forms of MreB protein that bear mutations identified in CBR-4830-resistant strains. Finally, employing the strains and reagents prepared and characterized during the course of these studies, we have begun to investigate the ability of analogues of CBR-4830 to inhibit the growth of both efflux-proficient and efflux-compromised P. aeruginosa through specific inhibition of MreB function.

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Дисертації з теми "CBR AGENTS"

Shen, Ying. "Élaboration d'ontologies médicales pour une approche multi-agents d'aide à la décision clinique." Thesis, Paris 10, 2015. http://www.theses.fr/2015PA100040/document.

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La combinaison du traitement sémantique des connaissances (Semantic Processing of Knowledge) et de la modélisation des étapes de raisonnement (Modeling Steps of Reasoning), utilisés dans le domaine clinique, offrent des possibilités intéressantes, nécessaires aussi, pour l’élaboration des ontologies médicales, utiles à l'exercice de cette profession. Dans ce cadre, l'interrogation de banques de données médicales multiples, comme MEDLINE, PubMed… constitue un outil précieux mais insuffisant car elle ne permet pas d'acquérir des connaissances facilement utilisables lors d’une démarche clinique. En effet, l'abondance de citations inappropriées constitue du bruit et requiert un tri fastidieux, incompatible avec une pratique efficace de la médecine.Dans un processus itératif, l'objectif est de construire, de façon aussi automatisée possible, des bases de connaissances médicales réutilisables, fondées sur des ontologies et, dans cette thèse, nous développons une série d'outils d'acquisition de connaissances qui combinent des opérateurs d'analyse linguistique et de modélisation de la clinique, fondés sur une typologie des connaissances mises en œuvre, et sur une implémentation des différents modes de raisonnement employés. La connaissance ne se résume pas à des informations issues de bases de données ; elle s’organise grâce à des opérateurs cognitifs de raisonnement qui permettent de la rendre opérationnelle dans le contexte intéressant le praticien.Un système multi-agents d’aide à la décision clinique (SMAAD) permettra la coopération et l'intégration des différents modules entrant dans l'élaboration d'une ontologie médicale et les sources de données sont les banques médicales, comme MEDLINE, et des citations extraites par PubMed ; les concepts et le vocabulaire proviennent de l'Unified Medical Language System (UMLS).Concernant le champ des bases de connaissances produites, la recherche concerne l'ensemble de la démarche clinique : le diagnostic, le pronostic, le traitement, le suivi thérapeutique de différentes pathologies, dans un domaine médical donné.Différentes approches et travaux sont recensés, dans l’état de question, et divers paradigmes sont explorés : 1) l'Evidence Base Medicine (une médecine fondée sur des indices). Un indice peut se définir comme un signe lié à son mode de mise en œuvre ; 2) Le raisonnement à partir de cas (RàPC) se fonde sur l'analogie de situations cliniques déjà rencontrées ; 3) Différentes approches sémantiques permettent d'implémenter les ontologies.Sur l’ensemble, nous avons travaillé les aspects logiques liés aux opérateurs cognitifs de raisonnement utilisés et nous avons organisé la coopération et l'intégration des connaissances exploitées durant les différentes étapes du processus clinique (diagnostic, pronostic, traitement, suivi thérapeutique). Cette intégration s’appuie sur un SMAAD : système multi-agent d'aide à la décision
The combination of semantic processing of knowledge and modelling steps of reasoning employed in the clinical field offers exciting and necessary opportunities to develop ontologies relevant to the practice of medicine. In this context, multiple medical databases such as MEDLINE, PubMed are valuable tools but not sufficient because they cannot acquire the usable knowledge easily in a clinical approach. Indeed, abundance of inappropriate quotations constitutes the noise and requires a tedious sort incompatible with the practice of medicine.In an iterative process, the objective is to build an approach as automated as possible, the reusable medical knowledge bases is founded on an ontology of the concerned fields. In this thesis, the author will develop a series of tools for knowledge acquisition combining the linguistic analysis operators and clinical modelling based on the implemented knowledge typology and an implementation of different forms of employed reasoning. Knowledge is not limited to the information from data, but also and especially on the cognitive operators of reasoning for making them operational in the context relevant to the practitioner.A multi-agent system enables the integration and cooperation of the various modules used in the development of a medical ontology.The data sources are from medical databases such as MEDLINE, the citations retrieved by PubMed, and the concepts and vocabulary from the Unified Medical Language System (UMLS).Regarding the scope of produced knowledge bases, the research concerns the entire clinical process: diagnosis, prognosis, treatment, and therapeutic monitoring of various diseases in a given medical field.It is essential to identify the different approaches and the works already done.Different paradigms will be explored: 1) Evidence Based Medicine. An index can be defined as a sign related to its mode of implementation; 2) Case-based reasoning, which based on the analogy of clinical situations already encountered; 3) The different semantic approaches which are used to implement ontologies.On the whole, we worked on logical aspects related to cognitive operators of used reasoning, and we organized the cooperation and integration of exploited knowledge during the various stages of the clinical process (diagnosis, prognosis, treatment, therapeutic monitoring). This integration is based on a SMAAD: multi-agent system for decision support

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Guo, Yuhan. "Metaheuristics for solving large size long-term car pooling problem and an extension." Thesis, Artois, 2012. http://www.theses.fr/2012ARTO0206/document.

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La dispersion spatiale de l'habitat et des activités de ces dernières décennies a fortement contribué à un allongement des distances et des temps de trajets domicile-travail. Cela a pour conséquence un accroissement de l'utilisation des voitures particulières, notamment au sein et aux abords des grandes agglomérations. Afin de réduire les impacts dus à l'augmentation du trafic routier, des services de covoiturage, où des usagers ayant la même destination se regroupent en équipage pour se déplacer, ont été mis en place partout dans le monde. Nous présentons ici nos travaux sur le problème de covoiturage régulier. Dans cette thèse, le problème de covoiturage régulier a été modélisé et plusieurs métaheuristiques de résolution ont été implémentées, testées et comparées. La thèse est organisée de la façon suivante: tout d'abord, nous commençons par présenter la définition et la description du problème ainsi que le modèle mathématique associé. Ensuite, plusieurs métaheuristiques pour résoudre le problème sont présentées. Ces approches sont au nombre de quatre: un algorithme de recherche locale à voisinage variable, un algorithme à base de colonies de fourmis, un algorithme génétique guidée et un système multi-agents génétiques auto-adaptatif. Des expériences ont été menées pour démontrer l'efficacité de nos approches. Nous continuons ensuite avec la présentation et la résolution d'une extension du problème de covoiturage occasionel comportant plusieurs destinations. Pour terminer, une plate-forme de test et d'analyse pour évaluer nos approches et une plate-forme de covoiturage sont présentées dans l'annexe
Nowadays, the increased human mobility combined with high use of private cars increases the load on environment and raises issues about quality of life. The extensive use of private cars lends to high levels of air pollution, parking problem, traffic congestion and low transfer velocity. In order to ease these shortcomings, the car pooling program, where sets of car owners having the same travel destination share their vehicles, has emerged all around the world. We present here our research on the long-term car pooling problem. In this thesis, the long-term car pooling problem is modeled and metaheuristics for solving the problem are investigated. The thesis is organized as follows. First, the definition and description of the problem as well as its mathematical model are introduced. Then, several metaheuristics to effectively and efficiently solve the problem are presented. These approaches include a Variable Neighborhood Search Algorithm, a Clustering Ant Colony Algorithm, a Guided Genetic Algorithm and a Multi-agent Self-adaptive Genetic Algorithm. Experiments have been conducted to demonstrate the effectiveness of these approaches on solving the long-term car pooling problem. Afterwards, we extend our research to a multi-destination daily car pooling problem, which is introduced in detail manner along with its resolution method. At last, an algorithm test and analysis platform for evaluating the algorithms and a car pooling platform are presented in the appendix

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Barlas, Irtaza. "A Multiagent Framework for a Diagnostic and Prognostic System." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/5290.

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A Multiagent Framework for a Diagnostic and Prognostic System Irtaza Barlas 124 Pages Directed By: Dr. George Vactsevanos The shortcomings of the current diagnostic and prognostic systems stem from the limitations of their frameworks. The framework is typically designed on the passive, open loop, static, and isolated notions of diagnostics, in that the framework does not observe its diagnostic results (open-looped), hence can not improve its performance (static). Its passivity is attributed to the fact that an external event triggers the diagnostic or prognostic action. There is also no effort in place to team-up the diagnostic systems for a collective learning, hence the implementation is isolated. In this research we extend the current approaches of the design and implementation of diagnostic and prognostic systems by presenting a framework based upon Multiagent systems. This research created novel architectures by providing such unique features to the framework, as learning, reasoning, and coordination. As the primary focus of the research the concept of Case-Based Reasoning was exploited to reason in the temporal domain to generate better prognosis, and improve the accuracy of detection as well as prediction. It was shown that the dynamic behavior of the intelligent agent helps it to learn over time, resulting in improved performance. An analysis is presented to show that a coordinated effort to diagnose also makes sense in uncertain situations when there are certain number of systems attempting to communicate certain number of failures, since there can be high probability of finding a shareable experience.

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Lee, Seung-joo. "Molecular mechanism for DNA recognition by DNA alkylating antitumor agents /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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Hung, Eugene. "Behavior-based remote executing agents." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3204641.

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Thesis (Ph. D.)--University of California, San Diego, 2006.
Title from first page of PDF file (viewed April 4, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 95-98).

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Vervoort, Hélène C. "Novel anticancer agents from Ascidiacea /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1999. http://wwwlib.umi.com/cr/ucsd/fullcit?p3035904.

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Gardner, David H. "Abracadabra: Key Agents of Mediation that Define, Create, and Maintain TV Fandom." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/communication_theses/95.

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From a media industries, fan studies, and emerging socio-cultural public relations perspective, this project pulls back the Hollywood curtain to explore two questions: 1) How do TV public relations practitioners and key tastemaker/gatekeeper media define, create, build, and maintain fandom?; and 2) How do they make meaning of fandom and their agency/role in fan creation from their position of industrial producers, cultural intermediaries, members of the audience, and as fans themselves? This project brings five influential, working public relations and media professionals into a conversation about two case studies from the 2010-2011 television season – broadcast network CBS’ Hawaii Five-0 and basic cable network AMC’s The Walking Dead. Each of these shows speaks to fandom in particular ways and are representative of the industry’s current approaches in luring specific audiences to TV. This study shows that the relationship between entertainment publicists and media is dynamic, intertwined, complex, and historically hidden.

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Ganley, Brian. "Investigations into the chemical mechanisms of biological activity by heterocyclic di-N-oxides and 1,2 benzodithiolan-3-one 1-oxides." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9999285.

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Bai, Shuang. "Effect of immunosuppressive agents on drug metabolism in rats." Thesis, Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008270.

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Ganley, Brian Christopher. "Investigations into the chemical mechanisms of biological activity by heterocyclic di-N-oxides and 1,2 benzodithiolan-3-one 1-oxides /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9999285.

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Книги з теми "CBR AGENTS"

Petkov, Plamen, Dumitru Tsiulyanu, Cyril Popov, and Wilhelm Kulisch, eds. Advanced Nanotechnologies for Detection and Defence against CBRN Agents. Dordrecht: Springer Netherlands, 2018. http://dx.doi.org/10.1007/978-94-024-1298-7.

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Petkov, Plamen, Dumitru Tsiulyanu, Wilhelm Kulisch, and Cyril Popov, eds. Nanoscience Advances in CBRN Agents Detection, Information and Energy Security. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-9697-2.

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K, Kokula Krishna Hari, ed. Frameworks for m-business Agent Development with CBD. Pondicherry, India: Association of Scientists, Developers and Faculties, 2014.

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San Francisco (Calif.). Office of the Controller. City Services Auditor Division. Municipal Transportation Agency: The Agency needs to improve cable car fare collection practices. San Francisco: Office of the Controller, 2007.

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Xanthos, Theodoros. Drugs in cardiopulmonary resuscitation. New York: Nova Science Publishers, 2011.

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Xanthos, Theodoros, and Theodoros Xanthos. Drugs in cardiopulmonary resuscitation. New York: Nova Science Publishers, 2011.

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Brazil. Secretaria de Biodiversidade e Florestas. Implementation of the CBD in Brazil: Issues on the agenda of COP9. [Brasília], Brazil: Ministry of the Environment, Secretariat for Biodiversity and Forests, 2008.

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Ravinel, Hubert de. Car j'aime et j'espère. [Montréal]: Fides, 1994.

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NATO Advanced Study Institute on Evolving Methods for Macromolecular Crystallography: the Structual Path to the Understanding of the Mechanism of Action of CBRN Agents (2005 Erice, Italy). Evolving methods for macromolecular crystallography: The structural path to the understanding of the mechanisms of action of CBRN agents. Dordrecht: Springer Verlag, 2007.

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The politics of agenda setting: The car and the shaping of public policy. Aldershot: Ashgate, 2000.

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Частини книг з теми "CBR AGENTS"

López, Beatriz, Carles Pous, Albert Pla, and Pablo Gay. "Boosting CBR Agents with Genetic Algorithms." In Case-Based Reasoning Research and Development, 195–209. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02998-1_15.

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Ontañón, Santiago, and Enric Plaza. "Collaborative Case Retention Strategies for CBR Agents." In Case-Based Reasoning Research and Development, 392–406. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-45006-8_31.

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Jordán, Jaume, Stella Heras, Soledad Valero, and Vicente Julián. "ArgCBR-CallCentre: A Call Centre Based on CBR Argumentative Agents." In Advances on Practical Applications of Agents and Multi-Agent Systems, 292–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38073-0_30.

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Corchado, Juan M., Juan Pavón, Emilio S. Corchado, and Luis F. Castillo. "Development of CBR-BDI Agents: A Tourist Guide Application." In Lecture Notes in Computer Science, 547–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-28631-8_40.

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Bajo, Javier, and Juan M. Corchado. "Evaluation and Monitoring of the Air-Sea Interaction Using a CBR-Agents Approach." In Case-Based Reasoning Research and Development, 50–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11536406_7.

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Rothkugel, Steffen, and Peter Sturm. "CarPAcities: Distributed Car Pool Agencies in Mobile Networks." In Agent Systems, Mobile Agents, and Applications, 178–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-540-45347-5_15.

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Hülseweh, Birgit, and Hans-Jürgen Marschall. "Detection and Analysis of Biological Agents." In CBRN Protection, 211–41. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527650163.ch8.

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Swan, Jerry, Eric Nivel, Neel Kant, Jules Hedges, Timothy Atkinson, and Bas Steunebrink. "Where is My Mind?" In The Road to General Intelligence, 17–22. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08020-3_3.

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AbstractThe research field of AI is concerned with devising theories, methods, and workflows for producing software artifacts which behave as intelligent subjects. Evidently, intelligence, as the property of an agent, is not of necessity inherited from the methods used to construct it: that a car has been assembled by robots does not make it a robot. Unfortunately, even this obvious distinction can sometimes be erased in some prominent published work. To wit: the statement, “an agent that performs sufficiently well on a sufficiently wide range of tasks is classified as intelligent” was recently published by DeepMind [273] to give context to a paper claiming to have developed “the first deep RL agent that outperforms the standard human benchmark on all 57 Atari games” [14]. This invites the inference that the range of the tasks (57 games) that have been achieved warrants calling the advertised agent ‘intelligent’. However, careful reading of the paper reveals that the authors have in fact developed 57 different agents. Granted, this was achieved using the same development method and system architecture, but 57 agents were nonetheless trained, rather than the claimed single agent. Here is a prime example of distilled confusion: a property (applicability to 57 tasks) of one construction method (instantiating the Agent57 system architecture) has just been ‘magically’ transferred to some 57 artifacts produced by the method.

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Altmann, Hans-Jürgen, Silke Oelze, and Bernd Niemeyer. "Chemical Agents - Small Molecules with Deadly Properties." In CBRN Protection, 67–101. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527650163.ch3.

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Altmann, Hans Jürgen, Martin Jung, and Andre Richardt. "Decontamination of Chemical Warfare Agents - What is Thorough?" In CBRN Protection, 351–82. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527650163.ch13.

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Тези доповідей конференцій з теми "CBR AGENTS"

"AN AGENT-BASED INFORMATION CUSTOMIZATION SYSTEM USING CBR AND ONTOLOGY." In 2nd International Conference on Agents and Artificial Intelligence. SciTePress - Science and and Technology Publications, 2010. http://dx.doi.org/10.5220/0002723702850290.

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Al Shorman, B. "Comprehensive review of soil stabilization agents." In Advanced Topics in Mechanics of Materials, Structures and Construction. Materials Research Forum LLC, 2023. http://dx.doi.org/10.21741/9781644902592-12.

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Abstract. Soil stabilization is a technique that is used in most construction projects to enhance the geotechnical and engineering properties of soil. There is a wide range of research studies related to soil stabilization techniques and agents, these studies discussed the effects of the different types of soil stabilization on soil, the most suitable agent type regarding soil classification, and the challenges that were founded during the application of these processes. Stabilization agents include traditional and non-traditional additives with their different categories were reviewed and discussed in this paper by presenting the results of the recent studies concerned with various types of soil stabilization agents in different laboratories and project tests with highlights on the enhancement of soil properties. In addition to increasing the compressive and shear strength parameters, Maximum Dry Density (MDD), and California Bearing Ratio (CBR) of the soil, the soil stabilization agents play a great role in decreasing the soil plasticity index, swelling, compressibility, porosity, permeability, and Optimum Moisture Content (OMC).

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da Silva Cendon Duran, Camila, Adriane Souza da Paz, and Mittermayer Barreto Santiago. "Vasculitis induced by biological agents used in Rheumatology: A Systematic Review." In Congresso Brasileiro de Reumatologia 2020. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2020.17012.

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"THE RE-USE OF EXPERIENCE THROUGH THE USE OF CBR IN INFORMATION SYSTEMS MODELLING." In 1st International Conference on Agents and Artificial Intelligence. SciTePress - Science and and Technology Publications, 2009. http://dx.doi.org/10.5220/0001665202970305.

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Russo Simon, Juliana, Bianca Pires Ihara, Reinan Tavares Campos, Claudia Alejandra Ayala Strabelli, Katia Tomie Kozu, Nádia Emi Aikawa, Adriana Maluf Elias, et al. "Children with rheumatic diseases and/or using immunosuppressive agents and COVID-19: is this a real concern?" In SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.1831.

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Martins, Ana, Daniela Oliveira, Frederico Rajão Martins, Filipe Oliveira Pinheiro, Maria Seabra Rato, Diogo Guimarães Fonseca, Salomé Garcia та ін. "Drug-induced lupus erythematosus secondary to anti-TNF-α agents in patients with axial spondyloarthritis and psoriatic arthritis". У SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.1868.

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"BIOLOGICAL AGENTS SPACING IN RHEUMATOID ARTHRITIS - EXPERIENCE OF A RHEUMATOLOGY SERVICE IN THE CENTRAL REGION OF SÃO PAULO- BRAZIL." In Congresso Brasileiro de Reumatologia 2020. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2020.17027.

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Ranzolin, Aline. "IMPACT OF OLD AGE ON THE PERSISTENCE AND SAFETY OF TREATMENT WITH BIOLOGIC AGENTS OR JAK INHIBITORS IN RHEUMATOID ARTHRITIS." In XXXIX Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2022. http://dx.doi.org/10.47660/cbr.2022.2132.

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Bredemeier, Markus. "THE EFFECT OF ANTIMALARIALS ON THE OVERALL SAFETY AND PERSISTENCE OF TREATMENT WITH BIOLOGIC AGENTS OR JAK INHIBITORS IN RHEUMATOID ARTHRITIS." In XXXIX Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2022. http://dx.doi.org/10.47660/cbr.2022.2090.

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Borges de Oliveira, Amanda, ALISSON PUGLIESI, RICARDO XAVIER, Licia Maria Henrique da Mota, MANOEL BARROS BERTOLO, Miguel Angel Gonzalez-Gay, GUSTAVO CITERA, and Luiz Sérgio F. de Carvalho. "Compared efficacy of rituximab, abatacept, and tocilizumab in patients with rheumatoid arthritis refractory to methotrexate or anti-TNF agents: a systematic review and network." In SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.1990.

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Звіти організацій з теми "CBR AGENTS"

Barnett, Natalie Beth. Biosecurity reference : CFR-listed agent and toxin summaries. Office of Scientific and Technical Information (OSTI), September 2003. http://dx.doi.org/10.2172/918268.

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Thompson, Marshall, and Ramez Hajj. Flexible Pavement Recycling Techniques: A Summary of Activities. Illinois Center for Transportation, July 2021. http://dx.doi.org/10.36501/0197-9191/21-022.

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Cold in-place recycling (CIR) involves the recycling of the asphalt portions (including hot-mix asphalt and chip, slurry, and cape seals, as well as others) of a flexible or composite pavement with asphalt emulsion or foamed asphalt as the binding agent. Full-depth reclamation (FDR) includes the recycling of the entire depth of the pavement and, in some cases, a portion of the subgrade with asphalt, cement, or lime products as binding agents. Both processes are extensively utilized in Illinois. This project reviewed CIR and FDR projects identified by the Illinois Department of Transportation (IDOT) from the Transportation Bulletin and provided comments on pavement designs and special provisions. The researchers evaluated the performance of existing CIR/FDR projects through pavement condition surveys and analysis of falling weight deflectometer data collected by IDOT. They also reviewed CIR/FDR literature and updated/modified (as appropriate) previously provided inputs concerning mix design, testing procedures, thickness design, construction, and performance as well as cold central plant recycling (CCPR) literature related to design and construction. The team monitored the performance of test sections at the National Center for Asphalt Technology and Virginia Department of Transportation. The researchers assisted IDOT in the development of a CCPR special provision as well as responded to IDOT inquiries and questions concerning issues related to CIR, FDR, and CCPR. They attended meetings of IDOT’s FDR with the Cement Working Group and provided input in the development of a special provision for FDR with cement. The project’s activities confirmed that CIR, FDR, and CCPR techniques are successfully utilized in Illinois. Recommendations for improving the above-discussed techniques are provided.

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Pflum, C. G., R. A. Van Konynenburg, and P. Krishna. Critical comments on the US Environmental Protection Agency Standards 40 CFR 191. Office of Scientific and Technical Information (OSTI), January 1993. http://dx.doi.org/10.2172/139789.

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Science, Fera. Analysis of CBD Products. Food Standards Agency, November 2022. http://dx.doi.org/10.46756/sci.fsa.cis490.

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The Food Standards Agency commissioned Fera Science Ltd. to carry out a survey to obtain a snapshot of CBD products on sale in England and Wales in order to inform FSA risk assessment of CBD products. Thirty CBD products were purchased from a range of online sellers from England and Wales. Samples comprised of two broad categories: oils and sprays, and edibles (including beverages). The sampling followed a scheme suggested by FSA. This is not a statistically representative sample of the market and instead provides a snapshot of the current market, to assist the design of future sampling and surveillance activity. There is the potential for residues of chemicals to be present in CBD products as a result of their natural occurrence in the raw material or arising from the manufacturing process, for example, mycotoxins, metals, pesticides, and the residues of solvents used to extract CBD. This study informs the FSA’s understanding of the type and levels of contaminants that may arise in CBD products. A wide range of analysis on CBD products was undertaken using accredited methods, for heavy metals, Polycyclic Aromatic Hydrocarbons (PAHs), pesticides, mycotoxins, CBD content and cannabinoid profiles. Analysis for residual solvents and additional mycotoxins was also carried out, but these were not accredited. The results of testing found the following: Heavy metals (cadmium, mercury & lead) and arsenic were not detected in the majority of samples, meaning levels were below the limits of quantification of the method. Seven samples contained lead, four samples arsenic and two samples contained cadmium. Mercury was not found in any sample. A definitive statement as to whether products exceed maximum levels cannot be made due to uncertainty as to whether products would be classified as a food (i.e. oil) or a food supplement. A low incidence of low levels of mycotoxins, with Fusarium mycotoxins found more frequently than aflatoxins and ochratoxin A, mostly at the methods reporting limit. Three samples were found to contain ochratoxin A at the methods reporting limit. A total of seven pesticide residues were found across all of the products (each product was tested for over 400 pesticides). There are no specific Maximum Residue Limits (MRL) for CBD products. One oil product was found to have PAHs above the regulated levels, if classed as a product for direct consumption. If classed as a food supplement the PAHs were within regulated levels. Three samples contained residual solvents. One product was over the MRL. Most products contained CBD close to the declared value. Two oils had substantially different levels than that declared (one higher and one lower). CBD was not detected in one of the drink products. These are potentially non-compliant with compositional and standards requirements. Delta 9-THC was detected in 87 % (26) of the samples analysed. Of these 40% (12) were found to have THC+ (the total sum of illicit cannabinoids in the product) above the 1mg threshold outlined in current Home Office guidance (Opens in a new window).

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Dunston, Amy Gale, and Peter C. Miller. Improving community based family planning services and the potential for increasing contraceptive prevalence in Bangladesh. Population Council, 1995. http://dx.doi.org/10.31899/rh1995.1029.

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This report contains descriptions of 13 family planning (FP) projects recently implemented in Bangladesh. The results in terms of the contraceptive prevalence rate (CPR) are analyzed to investigate the degree to which improved FP service delivery in Bangladesh can increase contraceptive use in the present status of demand, investigate the programmatic factors most associated with increased prevalence, and make these projects more widely known. Criteria for inclusion included coverage of a geographic area where household distribution of contraceptive supplies was available, and where at least one measurement of CPR has been made through credible survey efforts since July 1988. The projects varied in design, intensity, programmatic focus, geographic area, implementing agency, and evaluating agency. All were rural or largely so. Primary conclusions are that improvements in the national program can be expected to lead to substantial increases in contraceptive prevalence; increased visitation rates, and greater efforts in basic training, density of fieldworkers, and use of NGO fieldworkers may be particularly effective in meeting unmet demand; although direct provision of services by NGOs seems most associated with high performance, the implication of this for the national program requires careful analysis.

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McDonagh, Marian S., Jesse Wagner, Azrah Y. Ahmed, Benjamin Morasco, Devan Kansagara, and Roger Chou. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: May 2021 Update. Agency for Healthcare Research and Quality (AHRQ), June 2021. http://dx.doi.org/10.23970/ahrqepccerplantpain3.

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Overview This is the third quarterly progress report for an ongoing living systematic review on cannabis and other plant-based treatments for chronic pain. The first progress report was published in January 2021 and the second in March 2021. The draft systematic review was available for public comment from May 19 through June 15, 2021, on the Agency for Healthcare Research and Quality (AHRQ) Effective Health Care website. The systematic review synthesizes evidence on the benefits and harms of plant-based compounds (PBCs), such as cannabinoids and kratom, used to treat chronic pain, addressing concerns about severe adverse effects, abuse, misuse, dependence, and addiction. The purpose of this progress report is to describe the cumulative literature identified thus far. This report will be periodically updated with new studies as they are published and identified, culminating in an annual systematic review that provides a synthesis of the accumulated evidence. Main Points In patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to <6 months): • Studies of cannabis-related products were grouped based on their tetrahydrocannabinol (THC) to cannabidiol (CBD) ratio using the following categories: high THC to CBD, comparable THC to CBD, and low THC to CBD. • Comparable THC to CBD ratio oral spray is probably associated with small improvements in pain severity and may be associated with small improvements in function. There was no effect in pain interference or serious adverse events. There may be a large increased risk of dizziness and sedation, and a moderate increased risk of nausea. • Synthetic THC (high THC to CBD) may be associated with moderate improvement in pain severity and increased risk of sedation, and large increased risk of nausea. Synthetic THC is probably associated with a large increased risk of dizziness. • Extracted whole-plant high THC to CBD ratio products may be associated with large increases in risk of withdrawal due to adverse events and dizziness. • Evidence on whole-plant cannabis, low THC to CBD ratio products (topical CBD), other cannabinoids (cannabidivarin), and comparisons with other active interventions was insufficient to draw conclusions. • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive deficits) and outcomes on the impact on opioid use were not reported. • No evidence on other plant-based compounds, such as kratom, met criteria for this review.

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Anderson, D. R., M. G. Marietta, and P. J. Jr Higgins. Regulatory issues for Waste Isolation Pilot Plant long-term compliance with U.S. Environmental Protection Agency 40 CFR 191B and 268. Office of Scientific and Technical Information (OSTI), October 1993. http://dx.doi.org/10.2172/142510.

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Baudais, Virginie, Annelies Hickendorff, Jaïr van der Lijn, Igor Acko, Souleymane Maiga, and Hussein Yusuf Ali. EU Military Training Missions: A Synthesis Report. Stockholm International Peace Research Institute, May 2022. http://dx.doi.org/10.55163/lfle9658.

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This paper draws overarching conclusions based on a synthesis of previously published case studies that examined the impact of EU military training missions (EUTMs) in Somalia (EUTM Somalia, 2010–), Mali (EUTM Mali, 2013–), the Central African Republic (CAR) (EUTM RCA, 2016–). It concludes that EUTMs are relevant niche operations. Despite difficult circumstances beyond the control of the missions, EUTM training and advisory efforts have increased the effectiveness of partner armed forces. While these gains have been marginal in CAR and Somalia, they have been a bit more pronounced in Mali. Yet, broader security sector reform and defence sector reform efforts to improve the accountability and governance of defence and security sectors have become bogged down. The main challenge is that EUTMs are generally mandated to implement largely technical and tactical agendas in contexts where the ongoing armed conflict and the politics of the security sector are not conducive to building professional national security forces. As a consequence EUTMs find themselves caught up in interlinked and partially overlapping dilemmas. This study concludes with seven partly overlapping recommendations to EU member states and to EUTMs to address the main limitations that are restricting the impact of the missions.

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Kudin, Roman, Prabhat Chand, and Anura Bakmeedeniya. Mitigating Nitrogen Oxides Exhaust Emissions from Petrol Vehicles by Application of a Fuel Additive. Unitec ePress, August 2020. http://dx.doi.org/10.34074/rsrp.083.

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This research has been commissioned by Eco Fuel Global Limited, a New Zealand-based company, to further evaluate the effects of their fuel-additive product on the tailpipe exhaust emissions of petrol cars. At the time this research was conducted (end of 2018), the product was still in development and had not been released to the market. Prior to the testing in this research, an initial pilot test was done for the same product on a single car (Nissan Pulsar 1998), which showed favourable results, with a reduction in hydrocarbons and oxides of nitrogen at the tailpipe by more than 70%. The current research included five test cars, all running on RON 95 fuel, with the years of manufacture ranging between 1994 and 2006, and the odometer readings between 112,004 km and 264,001 km. The effects of the fuel-additive product were assessed by comparing the emissions from a car running on standard fuel with the emissions from the same car after it completed a road run (250±20 km) on the additive-treated fuel. The exhaust emissions were measured using the AVL series 4000 Emission Tester, which analyses five components: carbon monoxide (CO), carbon dioxide (CO2), oxides of nitrogen (NOX), hydrocarbons (HC) and oxygen (O2). The most noticeable outcome of using the fuel-additive product was the reduction in the concentration of oxides of nitrogen in the tailpipe exhaust (by up to 27.7%), when compared with the same cars running on standard fuel. In addition, the results showed a decrease in residual oxygen concentration, which normally indicates more complete utilisation of O2 as an oxidising agent. Mitigating Nitrogen Oxides Exhaust Emissions from Petrol Vehicles by Application of a Fuel Additive Dr Roman Kudin, Prabhat Chand and Anura Bakmeedeniya 2 The changes for other emission parameters were either relatively small (below 1%) or were not statistically significant. The application of such fuel-additive products could be beneficial for mitigating nitrogen oxides exhaust emissions from petrol vehicles in countries with ageing car fleets. These include New Zealand, which has a relatively high proportion of old cars in use, with no government-run scrappage scheme, and without a mandatory objective emissions testing.

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Frangos, T. G. The Environmental Protection Agency`s proposed regulation of low level radioactive waste (40 CFR Part 193): A Department of Energy overview. Office of Scientific and Technical Information (OSTI), November 1989. http://dx.doi.org/10.2172/330565.

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