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Статті в журналах з теми "Caslon type"
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Lane, J. A. "The Caslon Type Specimen in the Museum Van Het Boek." Quaerendo 23, no. 1 (1993): 78–79. http://dx.doi.org/10.1163/157006993x00235.
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Benard, Leo, and Anthony Conway. "A multivariable Casson–Lin type invariant." Annales de l'Institut Fourier 70, no. 3 (June 26, 2020): 1029–84. http://dx.doi.org/10.5802/aif.3330.
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Harper, Eric, and Nikolai Saveliev. "A Casson–Lin type invariant for links." Pacific Journal of Mathematics 248, no. 1 (October 1, 2010): 139–54. http://dx.doi.org/10.2140/pjm.2010.248.139.
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JOHANNES, JEFF. "A TYPE 2 POLYNOMIAL INVARIANT OF LINKS DERIVED FROM THE CASSON-WALKER INVARIANT." Journal of Knot Theory and Its Ramifications 08, no. 04 (June 1999): 491–504. http://dx.doi.org/10.1142/s021821659900033x.
Повний текст джерелаАнотація:
Simple formulas involving only linking numbers and surgery coefficients are presented for computing how the Casson-Walker invariant changes under crossing changes in a framed link presenting a 3-manifold. These formulas greatly simplify computations of the Casson-Walker invariant and can be used to define a type two polynomial invariant of unframed links.
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Park, Young W., and George F. W. Haenlein. "A2 Bovine Milk and Caprine Milk as a Means of Remedy for Milk Protein Allergy." Dairy 2, no. 2 (April 6, 2021): 191–201. http://dx.doi.org/10.3390/dairy2020017.
Повний текст джерелаАнотація:
A new type of cow’s milk, called A2 milk, has appeared in the dairy aisles of supermarkets in recent years. Cows’ milk generally contains two major types of beta-casein as A1 and A2 types, although there are 13 genetic variants of β-casein: A1, A2, A3, A4, B, C, D, E, F, H1, H2, I and G. Studies have shown that A1 β-casein may be harmful, and A2 β-casein is a safer choice for human health especially in infant nutrition and health. The A2 cow milk is reportedly easier to digest and better absorb than A1 or other types of milk. The structure of A2 cow’s milk protein is more comparable to human breast milk, as well as milk from goats, sheep and buffalo. Digestion of A1 type milk produces a peptide called β-casomorphin-7 (BCM-7), which is implicated with adverse gastrointestinal effects on milk consumption. In addition, bovine milk contains predominantly αs1-casein and low levels or even absent in αs2-casein, whereby caprine milk has been recommended as an ideal substitute for patients suffering from allergies against cow milk protein or other food sources. Since goat milk contains relatively low levels of αs1-casein or negligible its content, and αs2-casein levels are high in the milk of most dairy goat breeds, it is logical to assume that children with a high milk sensitivity to αs1-casein should tolerate goat milk well. Cow milk protein allergy (CMPA) is considered a common milk digestive and metabolic disorder or allergic disease with various levels of prevalence from 2.5% in children during the first 3 years of life to 12–30% in infants less than 3 months old, and it can go up to even as high as 20% in some countries. CMPA is an IgE-mediated allergy where the body starts to produce IgE antibodies against certain protein (allergens) such as A1 milk and αs1-casein in bovine milk. Studies have shown that ingestion of β-casein A1 milk can cause ischemic heart disease, type-1 diabetes, arteriosclerosis, sudden infant death syndrome, autism, schizophrenia, etc. The knowledge of bovine A2 milk and caprine αs2-casein has been utilized to rescue CMPA patients and other potential disease problems. This knowledge has been genetically applied to milk production in cows or goats or even whole herds of the two species. This practice has happened in California and Ohio, as well as in New Zealand, where this A2 cow milk has been now advanced commercially. In the USA, there have been even promotions of bulls, whose daughters have been tested homozygous for the A2 β-casein protein.
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Gao, Xiaoping. "The interface of linguistic difficulty and task type on the use of the Chinese ba construction by L2 learners." Chinese as a Second Language Research 3, no. 1 (May 1, 2014): 27–51. http://dx.doi.org/10.1515/caslar-2014-0002.
Повний текст джерелаАнотація:
AbstractThis study investigates the effects of linguistic difficulty and task type on the use of Chinese ba construction by second language learners. One hundred and ten adult learners completed four tasks orally (i.e., an oral production task prompted by video clips, an oral imitation task, a grammaticality judgement task and a correction task), as well as a background questionnaire and a one-on-one post-task interview. Twenty-two native speakers of Chinese served as baseline. Results demonstrate that the variable type of the Chinese ba construction which is subject to functional constraints is harder to learn than the obligatory type which is subject to obligatory syntactic constraints, and that the oral tasks were more challenging to perform than the metalinguistic tasks. The findings suggest that a series of factors including functional value and discourse context contribute to the linguistic difficulty of Chinese grammar features. The processing constraints of completing tasks and their interaction with linguistic characteristics explain the learning difficulty of the two types of the ba construction.
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Adina-Mirela, Ariton, Neculai-Văleanu Andra-Sabina, and Poroșnicu Ioana. "Impact of A2 milk on human health and the dairy industry - a review." Scientific Papers Journal VETERINARY SERIES 66, no. 4 (December 15, 2023): 96–99. http://dx.doi.org/10.61900/spjvs.2023.04.16.
Повний текст джерелаАнотація:
In recent years, a new type of cow's milk, called "A2 milk," has been introduced to the market. This type of milk was first marketed in New Zealand and has since gained a presence in the markets of several countries. It mainly contains two types of β-casein: the A1 and A2 variants. In recent years, researchers have studied the possible implications of the composition of the β casein protein fraction for the manifestation of a new intolerance: milk protein intolerance. Casein is the main component of milk proteins, of which approximately 30-35% is beta-casein. A2 beta-casein has proline at position 67 of the protein amino acid chain, while A1 beta-casein has histidine at that position; this is associated with a possibility of gastrointestinal discomfort due to β-casomorphin-7 (BCM-7) released during gastrointestinal digestion. The purpose of this review is to provide an update on the impact of A2 milk on human health as well as on its many technological qualities for the production of dairy products with improved health benefits for consumers.
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Diamante, Lemuel M., Peter A. Munro, and Michael G. Weeks. "Moisture sorption behaviour of mineral acid, lactic and rennet caseins in the temperature range 27–80 °C." Journal of Dairy Research 59, no. 3 (August 1992): 307–19. http://dx.doi.org/10.1017/s0022029900030582.
Повний текст джерелаАнотація:
SummaryThe moisture desorption isotherms of mineral acid, lactic and rennet caseins were determined at ˜ 28, 55 and 80 °C. The isotherms were all sigmoid type II according to the BET (Brunauer et al. 1938) classification. A modified Henderson equation was found best to describe the relationship of equilibrium moisture content, water activity (aw) and temperature for all three types of casein. BET monolayer moisture contents and heats of desorption of the three types of casein were calculated. Equilibrium moisture contents at aw 0·432 and 30 °C for mineral acid casein made under a range of manufacturing conditions varied significantly depending on the drying conditions. More severe drying conditions produced lower equilibrium moisture contents.
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Zentner, Raphael. "A vanishing result for a Casson-type instanton invariant." Proceedings of the London Mathematical Society 109, no. 6 (August 24, 2014): 1507–48. http://dx.doi.org/10.1112/plms/pdu030.
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Devi, Mamta, and Urvashi Gupta. "Magneto-Convection in Casson Nanofluids with Three Different Boundaries." Journal of Nanofluids 12, no. 5 (June 1, 2023): 1351–59. http://dx.doi.org/10.1166/jon.2023.2024.
Повний текст джерелаАнотація:
This paper is centered on the numerical and analytical solution of a non-Newtonian Casson nanofluid flow problem in the presence of vertical magnetic field. Brownian motion and thermophoretic forces are introduced due to the addition of nanoparticles and; the magnetic field adds an extra Lorentz’s force term along with Maxwell’s equations. Using Normal mode technique, the system of PDEs with the corresponding boundary conditions is reduced to a system of ODEs. The Galerkin-type weighted residual method is used to get a numerical solution for the formulated differential system. Numerical simulation is carried out to make the investigation helpful for practical applications like nano-drug delivery systems as in clinical and medical research, magnets are extremely important to create three-dimensional images of anatomical and diagnostic importance from nuclear magnetic resonance signals. Comparisons of the numerical results with previously published results are made and fine agreements are noted for the considered values of the parameters. The impact of magnetic field, Casson parameter and nanoparticle parameters are discussed for different types of boundary conditions (free–free, rigid-free and rigid–rigid). The system is found to be the most stable for more realistic rigid–rigid boundaries out of three different boundaries. For the purpose of numerical computations, blood has been considered as the Casson nanofluid. The novelty of the work lies in the fact that the strong stabilizing influence of Lorentz force on blood-based Casson nanofluid enables the red blood cells to pass through the blood in a more streamlined fashion which may play a significant role in human health, more specifically in the cardiovascular system. Further, although the Casson parameter hastens the onset of convection yet Casson fluids are more stable as compared to regular fluids.
Дисертації з теми "Caslon type"
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Harper, Eric. "Casson-Lin Type Invariants for Links." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/372.
Повний текст джерелаАнотація:
In 1992, Xiao-Song Lin constructed an invariant h of knots in the 3-sphere via a signed count of the conjugacy classes of irreducible SU(2)-representations of the fundamental group of the knot exterior with trace-free meridians. Lin showed that h equals one-half times the knot signature. Using methods similar to Lin's, we construct an invariant of two-component links in the 3-sphere. Our invariant is a signed count of conjugacy classes of projective SU(2)-representations of the fundamental group of the link exterior with a fixed 2-cocycle and corresponding non-trivial second Stiefel--Whitney class. We show that our invariant is, up to a sign, the linking number. We further construct, for a two-component link in an integral homology sphere, an instanton Floer homology whose Euler characteristic is, up to sign, the linking number between the components of the link. We relate this Floer homology to the Kronheimer-Mrowka instanton Floer homology of knots. We also show that, for two-component links in the 3-sphere, the Floer homology does not vanish unless the link is split.
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Büeler, Thomas. "Casein-Polymorphismus und gerinnungsrelevante Eigenschaften von Milch Schweizerischer Ziegenrassen /." [S.l.] : [s.n.], 2002. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=14876.
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Zäch, Regina. "Ökologie und Ausbreitung von Neophyten auf dem Monte Caslano im Südtessin Ecology and distribution of alien plant species (neophytes) on Monte Caslano in Southern Switzerland /." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, Geobotanisches Institut, 2005. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=178.
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Lluch, Porres Cristina. "Click and click-type chemistries in castor and sunflower oil-based monomers and polymers." Doctoral thesis, Universitat Rovira i Virgili, 2013. http://hdl.handle.net/10803/129159.
Повний текст джерелаАнотація:
El desenvolupament de materials polimèrics a partir de fonts renovables està rebent un interès creixent degut a la incertesa en el preu i les reserves d’olis i a aspectes mediambientals.
A més a més, maximitzar els beneficis d’emprar fonts renovables requereix l’aplicació de metodologies químiques altament sostenibles i eficients, exemplificades per les reacciones Click o tipus Click. D’altra banda, el disseny de polímers funcionalitzats amb propietats modulables i per tant, amb una aplicació més amplia, també és consistent amb el concepte de sostenibilitat. En aquest sentit, en aquesta tesi, hem explorat la diversitat d’oportunitats que aquestes transformacions ens ofereixen en els diferents estadis de la producció de polímers (síntesi de monòmers, polimerització i modificació de polímers) basats en l’àcid undecilènic i oleic, com a derivats de l’oli de ricí i girasol, respectivament. En concret, hem explorat la química tiol-eno tant per preparar nous monòmers policarboxílics com per polimeritzar derivats d’àcids grassos i modificar els finals de cadena de nous macromonomers. També hem explorat la química tiol-ino com a eina de polimerització de derivats d’àcids grassos alquínics. D’altra banda, s’ha preparat un poliester derivat de l’oli de ricí funcionalitzat amb grups brom i s’ha estudiat la substitució nucleòfila d’aquests grups amb tiols, amines i àcids carboxílics. Finalment l’aplicació dels diferents polímers sintetitzats, en l’alliberament controlat de fàrmacs així com també com a recobriments antimicrobials, ha estat avaluada.The development of polymeric materials from renewable resources is receiving considerable attention as a consequence of the depleting of fossil resources and environmental issues. Moreover, maximizing the benefits of using renewable feedstocks requires the utilization of sustainable and efficient chemical transformations, exemplified by Click/Click-type chemistry reactions. In addition, the design of highly functionalized polymers with adjustable properties and thus, broader applicability is also consistent with the concept of sustainability. To this aim, in this thesis, we have explored the wide opportunities that these efficient transformations can offer in the different steps involved in the production of polymers (monomer synthesis, polymerization and polymer modification) based on undecylenic and oleic acids, as castor and sunflower oil derivatives. In particular, we have explored thiol-ene couplings to prepare new polycarboxylic monomers but also to polymerize fatty acids derivatives as well as post-modify the chain-ends of new biobased macromonomers. Thiol-yne chemistry has been also explored as polymerization tool of alkynic fatty acid derivatives. In addition, a bromine containing polyester derived from castor oil has been also prepared and its nucleophilic substitution with thiols, amines and carboxylic acids has been studied. Finally, the application of the new synthesized polymers as drug delivery carriers or antimicrobial coatings has been evaluated.
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Pyzocha, Neena Kenton. "Discovery and biochemical characterization of Casl3b, a Type VI-B CRISPR-Associated RNA-Guided RNase." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/111309.
Повний текст джерелаАнотація:
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2017.Vita. Cataloged from PDF version of thesis.
Includes bibliographical references.
Targeted methods to perturb nucleic acid sequences or epigenetic modifications enable better understanding of nucleic acid function or dysfunction in disease. Particular CRISPR-associated (Cas) proteins are used for targeted DNA editing because they are easy to use, precise, and specific. CRISPR-Cas systems function in microbes as adaptive immune systems and are composed of endonuclease protein(s) with targeting guide RNAs that together provide interference against foreign nucleic acids. CRISPR-Cas systems exhibit wide diversity, with the ability to target DNA or RNA, and some large single effector Class 2 Cas proteins have been harnessed for genome engineering. There is an interest to find and characterize additional Class 2 Cas proteins, especially ones that target RNA, to enable further targeting capabilities. A large computational database search was conducted to find a large uncharacterized protein within 10 kilobases of a CRISPR array and from this search casl3b was identified. The casl3b loci may contain the genes csx27 or csx28 and one or two CRISPR arrays with canonical or long direct repeats. Experimentally, purified Casl3b processes its own CRISPR array(s) into crRNA(s) and Casl3b with either crRNA architecture targets single stranded RNA cleavage using its HEPN domains. SsRNA cleavage occurs at pyrimidine residues and is constrained by 5' and 3' protospacer-flanking sequences on the target. Casl3b also displays the collateral effect, a non-specific cleavage of ssRNAs after targeted cleavage. Casl3b with mutated HEPN domains lose ssRNA cleavage activity but maintain strong, targeted binding capacity. Genetically, Casl3b-mediated RNA interference occurs with Casl3b alone and is repressed by Csx27 or enhanced by Csx28. Casl3b is characterized as a Type VI-B CRISPR-Cas system and represents the second Class 2 Cas protein to target RNA, the other being Casl3a (C2c2). Future studies of Casl3b are warranted to better understand its functional mechanisms, specificity, role of small proteins, and acquisition. Casl3b could be developed into a suite of tools for transcriptome engineering to mediate RNA translation, splicing, or deposition of epitranscriptomic marks. Casl3b could also be utilized for RNA diagnostic or RNA imaging assays. Identifying and characterizing novel CRISPR-Cas systems opens new opportunities for utilizing Cas enzymes for biomedical advances.
by Neena Kenton Pyzocha.
Ph. D.
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Queiroz, Mariana Araujo Ribeiro. "Tratamento da distonia cervical com fisioterapia: estudo de 20 casos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-03072012-091938/.
Повний текст джерелаАнотація:
INTRODUÇÃO: Apesar da terapia com toxina botulínica ser o tratamento de escolha para a distonia cervical, admite-se que um tratamento multidisciplinar, agregando a fisioterapia ao tratamento com toxina botulínica, poderia acrescentar maiores benefícios aos pacientes com distonia cervical; sendo assim, o objetivo primário deste estudo foi avaliar o efeito da associação da toxina botulínica a um protocolo de fisioterapia na gravidade da distonia cervical, incapacidade e dor; e o objetivo secundário foi avaliar o efeito desta associação na qualidade de vida de pacientes com distonia cervical. MÉTODOS: Participaram deste estudo controlado aberto quarenta de setenta pacientes com distonia cervical, tratados no Ambulatório de Distúrbios do Movimento do Departamento de Neurologia da Faculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo. Antes de serem submetidos à aplicação da toxina botulínica, os pacientes foram avaliados por um médico da equipe, e esperava-se que neste dia os pacientes estivessem sem a ação da medicação. Todos os pacientes avaliados foram convidados a participar do programa de fisioterapia, e conforme a disponibilidade de aderir ao programa dos mesmos, chegou-se ao número de vinte pacientes em G1 (fisioterapia e toxina botulínica) e vinte pacientes em G2 (toxina botulínica), sendo esta amostra de conveniência. Para G2, foram escolhidos os primeiros vinte pacientes consecutivos que não poderiam aderir ao programa fisioterapêutico. Os pacientes de G1 e G2 foram reavaliados após quarenta e cinco dias. As escalas utilizadas foram a Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) e a Short-Form Health Survey (SF-36). Foi proposto um novo modelo de tratamento para pacientes com distonia cervical que seriam submetidos a um protocolo fisioterapêutico, baseado em três principais abordagens: aprendizagem motora, cinesioterapia e estimulação elétrica funcional na musculatura antagonista ao padrão distônico. Os pacientes de G1 foram tratados por um período de quatro semanas, a frequência era diária (cinco vezes por semana) e a duração da sessão em média uma hora e quinze minutos. RESULTADOS: As características demográficas iniciais dos indivíduos não diferiram significativamente entre os dois grupos tratados, em apenas um dos itens avaliados (tempo de tratamento) houve diferença entre grupos no momento inicial. Os resultados dos tratamentos na qualidade de vida foram avaliados pela escala SF-36, esta dividida em dois grandes domínios: aspectos físicos e aspectos emocionais. Em relação aos aspectos físicos, G1 apresentou melhora significativa comparando-se antes e depois do tratamento (intragrupo) em três subdomínios: capacidade funcional, limitação por aspectos físicos e dor; em G2 não houve melhora significativa em nenhum dos quatro subdomínios. Houve também uma diferença entre G1 e G2 depois dos tratamentos (entre grupos) em dois subdomínios: limitação por aspectos físicos e dor. Em relação aos aspectos emocionais, em G1, houve melhora significativa nos seguintes subdomínios depois do tratamento (intragrupo): vitalidade, aspectos sociais e saúde mental. Houve também uma diferença entre G1 e G2 depois dos tratamentos (entre grupos) em dois subdomínios: vitalidade e saúde mental. Não houve melhora em G2 nos subdomínios dos aspectos emocionais. A avaliação das características e gravidade da distonia cervical, medida pela TWSTRS, demonstrou melhora significativa de G1 e G2 após os tratamentos que foram submetidos (intra grupos) em duas subescalas: gravidade (I) e incapacidade (II). Na subescala de dor (III), apenas G1 apresentou melhora intragrupo após o tratamento a que foi submetido; houve também, neste mesmo subdomínio, diferença significativa entre G1 e G2 depois dos tratamentos, entre grupos. CONCLUSÕES: O presente estudo avaliou possibilidade de que a utilização da toxina botulínica, junto a um protocolo de fisioterapia facilmente reprodutível, poderia agregar melhoras em sintomas como gravidade da doença, incapacidade, dor e qualidade de vida de uma população de indivíduos com distonia cervical, e os resultados obtidos permitiram negar as hipóteses nulas. Novas pesquisas são necessárias para confirmar esses achados e solidificar a reabilitação neurológica como um tratamento eficaz no manejo da distonia cervicalINTRODUCTION: Despite the fact that therapy with botulinum toxin is considered the best treatment for cervical dystonia, it is assumed that a multidisciplinary treatment, adding physical therapy to the botulinum toxin treatment could provide additional gains to patients with cervical dystonia. The primary objective of this study was to evaluate the effect of the combination of botulinum toxin and physical therapy on severity of cervical dystonia, disability and pain. The secondary objective was to evaluate the effect of this combination on the quality of life in patients with cervical dystonia. METHODS: forty patients of seventy with cervical dystonia from the Ambulatório de Distúrbios do Movimento do Departamento de Neurologia da Faculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo attended this open- controlled study. Before receiving an application of botulinum toxin, the patients were evaluated by a neurologist and it was assumed that patients were not under any effect of the medication (botulinum toxin). All patients were asked to participate in a physical therapy program, and according to the patients availability to join the program, we reached the number of twenty patients in G1 (physical therapy and botulinum toxin) and in G2 (botulinum toxin only), the first twenty consecutive patients who couldnt participate in the physical therapy program were chosen. This was a convenience sample. Patients of G1 and G2 were revaluated after forty five days, and the evaluation scales used was the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and Short-Form Health Survey (SF-36). A new model of physical therapy treatment was applied to patients with cervical dystonia, and it was based on three main approaches: motor learning, kinesiotherapy and functional electrical stimulation on the antagonist muscles of the dystonic pattern. The patients in G1 were treated daily for a period of four weeks, and each session lasted one hour and fifteen minutes. RESULTS: The demographic characteristics of individuals didnt differ significantly between two treated groups, but there was a difference between groups in the initial moment (baseline) in only one feature evaluated (time of treatment). The SF-36 scale was used to evaluate the results of the treatments for quality of life, and was divided into two big domains: physical and emotional aspects. When analyzing physical aspects, G1 showed a significant improvement when comparing before and after the proposed treatment (inside group) in three subdomains: physical functioning, role-physical and body pain; in G2 there was no improvement in any of the four subdomains. A difference between G1 and G2, after the treatments (between groups), was also seen in two subdomains: role-physical and body pain. In relation to emotional aspects, in G1, after the treatment (intra-group), there was a significantly improvement in vitality, social functioning and mental health. There was also a difference between G1 and G2 after the treatment (between groups) in two subdomains: vitality and mental health. There was no improvement in G2 in any domains of the social aspects. Severity of cervical dystonia showed a significant improvement of G1 and G2 after treatments (intra-group) in two subdomains: severity (I) and disability (II). In subscale pain (III), only patients of G1 showed a significant improvement intra-group after the treatment; in this subdomain there was also a significant difference between groups after the treatments (G1 and G2). CONCLUSIONS: The present study showed that botulinum toxin, combined with an easily reproducible physical therapy protocol, could improve symptoms like severity of cervical dystonia, disability, pain and quality of life, in a population of individuals with cervical dystonia, and these results makes it possible to deny the null hypothesis. Other studies are needed to confirm these findings and solidify neurologic rehabilitation as an effective cervical dystonia treatment approach
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Auclair, Emmanuel. "Les Surfaces et invariants de type fini en dimension 3." Phd thesis, Université Joseph Fourier (Grenoble), 2006. http://tel.archives-ouvertes.fr/tel-00113863.
Повний текст джерелаАнотація:
Cette thèse porte sur les invariants des sphères d'homologie entière de dimension 3, et en particulier sur les invariants de type fini pour la filtration de Goussarov-Habiro.Dans une première partie, on étudie la variation d'un invariant de degré 2n après chirurgie le long d'une surface par un élément du 2n-ième terme de la série centrale descendante du groupe de Torelli. Dans le cas d'un commutateur de 2n éléments du groupe de Torelli, on exprime cette variation en fonction de l'homomorphisme de Johnson évalué sur ces 2n éléments et du système de poids de l'invariant.
Le calcul des claspers de Goussarov-Habiro donne des équivalences topologiques entre des chirurgies sur des corps en anses plongés dans les variétés. Ce calcul a déjà permis de préciser le comportement des invariants de type fini lors de nombreuses modifications topologiques. La deuxième partie de cette thèse est consacrée à un raffinement de ce calcul. Ce raffinement est ensuite appliqué à l'obtention d'une formule de chirurgie géométrique sur les noeuds pour les invariants de degré 4, c'est-à-dire que l'on exprime la variation d'un tel invariant après chirurgie sur un noeud en fonction d'invariants de courbes tracées au voisinage d'une surface de Seifert de ce noeud.
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Quinkenstein, Stephan. "Lymphoproliferation und Antigenspezifität von Lymphozyten frisch manifestierter Typ-I-Diabetiker gegen die Proteine bovines Serum-Albumin und [beta]-Casein [Beta-Casein] sowie Insulin." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969257120.
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Rodrigues, Maria Inês Vieira. "Hérnia discal intervertebral tipo II toracolombar em cães : diagnóstico e tratamento cirúrgico de sete casos clínicos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/12820.
Повний текст джерелаАнотація:
Dissertação de Mestrado integrado em Medicina VeterináriaAs hérnias discais intervertebrais tipo II toracolombares, tipicamente associadas ao processo de degenerescência fibrosa que afeta os discos intervertebrais, consistem na protrusão do núcleo pulposo associada a um enfraquecimento e rutura parcial das fibras do anel fibroso. O resultado é a extensão focal de ambas as estruturas para o canal vertebral, com compressão crónica e progressiva da medula espinhal e ligamento longitudinal dorsal. A doença é sobretudo reconhecida em animais mais velhos, de raças não condrodistróficas de grande porte, podendo no entanto afetar raças condrodistróficas. Os animais apresentam-se geralmente com uma história clínica crónica e progressiva e sinais clínicos ligeiros como ataxia dos membros pélvicos e paraparésia ambulatória. O diagnóstico é baseado nos dados do animal, história pregressa, resultados do exame neurológico, radiografias simples e o diagnóstico definitivo requer imagiologia avançada como mielografia, tomografia computorizada (TC) ou ressonância magnética (RM). A RM é considerado o exame imagiológico de eleição para o diagnóstico da doença e caracterização das lesões associadas. O tratamento pode ser conservador, com recurso a anti-inflamatórios, repouso e fisioterapia, ou cirúrgico. O tratamento cirúrgico poderá incluir técnicas descompressivas como hemilaminectomia, minihemilaminectomia, corpectomia lateral ou técnicas de estabilização vertebral. O prognóstico é mais reservado, independentemente do tratamento instituído e, a longo prazo muitas vezes não se revela satisfatório O objetivo da componente prática deste trabalho é contribuir com informação referente à abordagem de cães afetados por hérnia discal intervertebral tipo II, através da exposição de sete casos clínicos com diagnóstico da doença tratados cirurgicamente, assim como revisar a literatura mais recente sobre o tema em questão. A análise permitiu na generalidade confirmar a informação recolhida, tendo-se verificado que a doença surge na maioria dos casos em cães de raça não condrodistróficas e em idade mais avançada. Os discos intervertebrais T12-T13, T13-L1 e L1-L2 surgem com frequência afetados. A RM revela-se bastante útil na avaliação e caracterização das lesões. A presença de múltiplas protrusões e espondilose deformante ventral é comum nestes pacientes. A abordagem clínica e cirúrgica dos animais afetados é bastante variável e a sua recuperação é muitas vezes incompleta, podendo permaner défices neurológicos residuais.
ABSTRACT - THORACOLOMBAR INTERVERTEBRAL DISC PROTRUSION IN DOGS: DIAGNOSIS AND SURGICAL TREATMENT IN SEVEN CLINICAL CASES - The thoracolumbar type II intervertebral disc herniation, typically associated with the fibrous metaplasia that affect the intervertebral discs, consist in the protrusion of the nucleus pulposus, associated with the weakening and partial rupture of the annulus fibrosus. The result is the focal extension of both structures to the vertebral canal, with progressive and chronic compression of the spinal cord and the dorsal longitudinal ligament. This disease is mostly found in older animals of nonchondrodistrophic large breeds, although it can also affect chondrodistrophic ones. The animals usually present a progressive and chronic clinical history and mild clinical signs such as ataxia of the hindlimbs and ambulatory paraparesis. The diagnosis is based on the animal’s signalment, clinical history, results of the neurological exam, radiographic findings, and the final diagnosis requires advanced imaging tests such as mielography, computed tomography (CT) or magnetic resonance imaging (MRI). The MRI is considered the imaging test of choice for the diagnosis of the disease and characterization of the associated lesions. The treatment can be conservative, resorting to anti-inflammatory drugs, rest and physiotherapy, or surgical. The surgical treatment may include decompressive technics such as hemilaminectomy, minihemilaminectomy, lateral corpectomy and vertebral stabilization techniques. The prognosis is more reserved, regardless of the chosen treatment and, in the long term, is often not satisfactory. The goal of the practical component of this dissertation is to contribute with information concerning the approach to dogs affected by intervertebral type II disc herniation, through the presentation of seven clinical cases diagnosed with this disease and that had surgical treatment, as well as to review the most recent literature on the subject. In general, the analysis made it possible to confirm the information consulted, and we were able to verify that the disease occurs in most cases in nonchondrodistrophic breeds and in dogs of older age. The intervertebral discs T12-T13, T13-L1 and L1-L2 frequently appear affected. MRI proved to be quite useful in the evaluation and characterization of the lesions. The presence of multiple protrusions and spondylosis deformans ventral is common in these patients. The clinical and surgical approach to the affected animals is quite variable and the recovery is often incomplete, and residual neurological deficits may remain.
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Branco, Sophie Vazão. "Avaliação de lesões de reabsorção dentária em felinos : estudo retrospetivo de 152 casos clínicos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2020. http://hdl.handle.net/10400.5/20590.
Повний текст джерелаАнотація:
Dissertação de Mestrado Integrado em Medicina VeterináriaAs lesões de reabsorção dentária (LRD) representam uma das doenças orais mais comuns nos gatos e a sua prevalência tem vindo a aumentar. Existe um interesse crescente na compreensão da patogenia desta doença e na identificação dos seus fatores etiológicos. Porém, apesar das várias teorias existentes, a etiologia das LRD felinas permanece desconhecida dificultando a sua prevenção. Estas lesões são encontradas com maior frequência nos molares e pré-molares mandibulares, sendo, por isso, recomendada uma avaliação cuidada destes dentes em particular. A avaliação radiográfica e a correta identificação do tipo (1, 2 ou 3) de LRD são essenciais para o diagnóstico e para a escolha do tratamento adequado, que, na maioria dos casos, consiste na extração dos dentes ou na amputação da coroa dentária. Este estudo de caso-controlo retrospetivo incluiu 152 gatos, tendo como objetivos avaliar a relação entre as LRD, a doença periodontal e a gengivoestomatite, determinar quais os dentes mais frequentemente afetados e a sua distribuição por género e raça, de forma a contribuir para o estudo da etiologia destas lesões. Os resultados obtidos revelaram que a gengivite local representa um fator de risco para o desenvolvimento de LR2 e LR3. A periodontite representa um fator de risco para o desenvolvimento de LRD, sem influência nas LR1, LR2 ou LR3 em particular. A estomatite e a estomatite caudal não foram identificados como fatores de risco. O tipo de dente afetado e a raça do animal influenciam o tipo de LRD existente. Nomeadamente, os dentes caninos e a raça Persa aumentam o risco de desenvolver LR2, contrariamente às LR1 que são mais prevalentes nos molares e pré-molares e menos prevalentes na raça Persa. Também se observou uma relação significativa entre a idade e o tipo de LRD desenvolvido, sendo que as LR1 se verificaram maioritariamente em animais jovens, ao contrário das LR2 e LR3 que ocorreram sobretudo em gatos mais velhos. O presente estudo contribuiu para o conhecimento de fatores associados às LRD, reforçando os conhecimentos anteriores e contribuindo com a identificação de algumas variáveis com influência nos tipos de LRD, nomeadamente a associação entre a raça Persa, o tipo de dente afetado e as LR2. São necessários mais estudos, utilizando amostras maiores para conseguir identificar outras variáveis com influência nas LRD e validar associações aqui identificadas.
ABSTRACT - EVALUATION OF FELINE TOOTH RESORPTION - RETROSPECTIVE STUDY OF 152 CLINICAL CASES - Feline tooth resorption (TR) represents one of the most common oral diseases in cats and its prevalence has been increasing. There is growing interest in understanding the pathogenesis of this disease and in identifying its etiological factors. However, despite the several existing theories, the aetiology of feline TR remains unknown, making its prevention difficult. These lesions are most commonly found on the mandibular molars and premolars; therefore, it is recommended to examine these particular teeth thoroughly during oral examinations. Radiographic evaluation and the correct identification of the type (1, 2 or 3) of TR are essential for diagnosis and selection of the appropriate treatment, which, in most cases, consists of tooth extraction or amputation of the dental crown. This retrospective case-control study included 152 cats and aimed to evaluate the relationship between TR, periodontal disease and gingivostomatitis, to determine which teeth are most frequently affected and their distribution by gender and breed, in order to contribute to the aetiologic study of these dental lesions. The results revealed that local gingivitis represents a risk factor for the development of TR2 and TR3. Periodontitis represents a risk factor for the development of TR, with no influence on TR1, TR2 or TR3 in particular. Stomatitis and caudal stomatitis were not identified as risk factors. In addition, the type of tooth affected and the cat’s breed have an influence on the type of TR. Namely, canine teeth and the Persian breed increase the risk of developing TR2, in contrast to TR1 which are more prevalent in molars and premolars and less prevalent in the Persian breed. There was also a significant relationship between age and the type of TR developed, with TR1 mostly affecting young animals, in contrast to TR2 and TR3 that mostly occurred in older cats. This study contributed to the knowledge of factors associated with TR, reinforcing the previous knowledge and contributing to the identification of some variables that influence the types of TR, namely the association between the Persian breed, the type of tooth affected and TR2. Further studies are needed using larger samples to be able to identify other variables with influence on TR and validate associations identified here.
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Книги з теми "Caslon type"
1
Stephen, Farrell, and Pollack Don, eds. Mythopoeia. [Chicago, Ill.?]: Tomasula, Farrel, Pollack, 1996.
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2
Ian, Fleming. Casino royale: A James Bond novel. New York: Penguin Books, 2002.
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3
Ian, Fleming. Casino Royale: Live and let die. London: Titan, 1990.
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4
The strange caseof Dr. Jekyll and Mr. Hyde. New York: Dover, 1991.
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5
Furst, Alan. Red gold: A novel. New York: Random House, 1999.
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6
Furst, Alan. Red gold. New York: Random House, 1999.
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McKay, Hilary. Saffy's angel. London: Hodder Children's Books, 2002.
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Furst, Alan. The world at night: A novel. New York: Random House Trade Paperbacks, 2002.
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Furst, Alan. The world at night. New York: Random House, 1996.
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Persons, Truman Streckfus. In Cold Blood: A true account of a multiple murder and its consequences. New York: Vintage Books, 1994.
Знайти повний текст джерелаЧастини книг з теми "Caslon type"
1
Wong, IpKin Anthony. "Vegas-Style Casinos in China: The Role of Customer Type and Gender on Casino Service Perceptions." In Cultural Perspectives in a Global Marketplace, 47–50. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-18696-2_16.
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"Dynasty: in which William Caslon makes Britain the type centre of the world." In Type. I.B.Tauris, 2004. http://dx.doi.org/10.5040/9780755621910.ch-002.
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"Casson type invariants." In Lecture Notes on Knot Invariants, 167–222. WORLD SCIENTIFIC, 2015. http://dx.doi.org/10.1142/9789814675970_0005.
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Juan, Bibiana, Ahmed A. K. Salama, Suha Serhan, Xavier Such, Gerardo Caja, Laura Pont, Fernando Benavente, Buenaventura Guamis, and Antonio-José Trujillo. "β-Casein: type A1 and A2." In Casein, 99–121. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-15836-0.00010-x.
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El-Bakry, Mamdouh, and Bhavbhuti M. Mehta. "Casein: types, applications and gastric digestion." In Casein, 1–13. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-15836-0.00020-2.
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Ruberman, Daniel, and Nikolai Saveliev. "Casson-Type Invariants from the Seiberg–Witten Equations." In New Ideas in Low Dimensional Topology, 507–24. WORLD SCIENTIFIC, 2015. http://dx.doi.org/10.1142/9789814630627_0013.
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"Lambeth key crime types." In The street casino, 308. Policy Press, 2014. http://dx.doi.org/10.51952/9781447317203.bm003.
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Pinna, Lorenzo A., Flavio Meggio, and Fernando Marchiori. "Type-2 Casein Kinases: General Properties and Substrate Specificity." In Peptides and Protein Phosphorylation, 145–69. CRC Press, 2018. http://dx.doi.org/10.1201/9781351075442-6.
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Fisher, Susan J., and Zen A. Werb. "The catabolism of extracellular matrix components." In Extracellular Matrix, 261–88. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199632213.003.0012.
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Abstract Breaching of the extracellular matrix (ECM) barrier by cells involves proteolytic enzymes capable of degrading the ECM components. The most important of these enzymes is the collagenase family of metalloproteinases which have been recently reviewed (1, 2). The members of this multigene family include Pump-1, three types of stromelysin, interstitial collagenase, and the 72 and 92 kDa gelatinases/type IV collagenases. These enzymes possess sequences necessary for maintenance of the zymogen forms, a zinc-binding catalytic domain, and various numbers of structural regions resembling those found in ECM components. The wide range of specificity that the metallo proteinases exhibit is important in growth, debridement after injury, tissue morphogenesis and remodelling, and invasion. For example, stromelysin degrades fibronectin, elastin, proteoglycan core proteins, and laminin as well as the non-helical regions of collagen types IV, V, VII, and IX and the amino terminus of collagen type I. Interstitial collagenases can degrade collagens of types I, II, III, VIII, and X, but the degradation of basement membrane collagens requires specialized enzymes that degrade type IV collagen. The latter proteinases can also degrade collagens of types V, VII, and X as well as fibronectin, denatured collagens, and casein. Tissue-type (tPA) and urokinase-type (uPA) plasminogen activators, members of the serine proteinase family, also play an important role in ECM degradation and these have been recently reviewed (3). They may act directly, cleaving fibronectin and other components. Alternatively, PAs may act as part of a proteinase cascade in which plasmin activates procollagenase and prostromelysin.
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Balik, Vojtěch. "CASLIN, Priorities of the Czech National Library, and Government Policy on Information and Libraries." In Library Automation in Transitional Societies, 120–33. Oxford University PressNew York, NY, 2000. http://dx.doi.org/10.1093/oso/9780195132625.003.0011.
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Abstract The aims of the Czech and Slovak Library Information Network (CASLIN) project were to connect Czech and Slovak libraries of any type and size to each other, so that they could share the Union Catalog, coordinate their acquisitions or substantially improve loan services, and to guarantee that any user, no matter where he is located, is at once able to communicate with the Union Catalog on-line. The participants undertook (as quoted from the “Statement of Intent;’ the launching document of the CASLIN project) “to lay a solid foundation of a nationwide library network providing both home and foreign users with easy, fast, and unrestricted access to the information stored in or mediated by the libraries and information centers:’
Тези доповідей конференцій з теми "Caslon type"
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Yu, Shaojuan, Xu Ding, Lin Li, Feng Pan, Shibo Xiong, and Yanhong Bai. "Fuzzy PID-type Iterative Learning Control for Electro-hydraulic Servo System." In 2010 International Conference on Computational Aspects of Social Networks (CASoN 2010). IEEE, 2010. http://dx.doi.org/10.1109/cason.2010.153.
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Xiaomei, Yan, Zhang Jilong, and Wang Zhishe. "Research on Optical Fiber Methane Gas Sensor of Spectral Absorption Type." In 2010 International Conference on Computational Aspects of Social Networks (CASoN 2010). IEEE, 2010. http://dx.doi.org/10.1109/cason.2010.17.
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Chiou, Che Wun, Jim-Min Lin, and Chiou-Yng Lee. "Fast Optimal Normal Basis Multiplier with Type-2kw Over GF (2m)." In 2010 International Conference on Computational Aspects of Social Networks (CASoN 2010). IEEE, 2010. http://dx.doi.org/10.1109/cason.2010.33.
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Chen, Shyi-Ming, and Yu-Chuan Chang. "Fuzzy Interpolative Reasoning Based on the Footprints of Uncertainty of Interval Type-2 Fuzzy Sets." In 2010 International Conference on Computational Aspects of Social Networks (CASoN 2010). IEEE, 2010. http://dx.doi.org/10.1109/cason.2010.132.
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Fu-Ja Kung, Pa-Hwa Lee, Yih-Ru Wang, Sin-Horng Chen, and Chen-Yu Chiang. "On finding word-level break-type formation rules for mandarin read speech." In 2015 International Conference Oriental COCOSDA held jointly with 2015 Conference on Asian Spoken Language Research and Evaluation (O-COCOSDA/CASLRE). IEEE, 2015. http://dx.doi.org/10.1109/icsda.2015.7357864.
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Ooms, Luc, Vincent Massaut, L. Noynaert, M. Braeckeveldt, and G. Geenen. "Dry Storage of the BR3 Spent Fuel in the CASTOR® BR3 Cask." In ASME 2003 9th International Conference on Radioactive Waste Management and Environmental Remediation. ASMEDC, 2003. http://dx.doi.org/10.1115/icem2003-5015.
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The BR3 reactor was the first PWR plant installed in Europe. Started in 1962, BR3 was definitely shut down on June 30th, 1987. Used at the beginning of its life as a training device for commercial plant operators, it was also used during its whole life as test-reactor for new fuel types and assemblies. Most of the spent fuel was stored in the deactivation pool of the plant for more than 15 years. The reactor being now in decommissioning, it was decided to remove the spent fuel from the plant. After comparison of different solutions, the long term storage in dual purpose storage casks was selected in 1997. The selected CASTOR-BR3® cask is designed as a transport and storage cask for accommodating 30 spent fuel assemblies. As a type B(U) cask fitted with shock absorbers, it meets the transport requirements according to the IAEA guidelines and fulfils also the conditions for cask storage.
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Yu, Jue, and Dafydd Gibbon. "Time Group types in Mandarin syllable annotations." In 2015 International Conference Oriental COCOSDA held jointly with 2015 Conference on Asian Spoken Language Research and Evaluation (O-COCOSDA/CASLRE). IEEE, 2015. http://dx.doi.org/10.1109/icsda.2015.7357881.
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Menasni, S., W. Hornebeck, L. Robert, and Y. Legrand. "ELASTASE TYPE ACTIVITY OF ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643360.
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Elastin degrading enzymes have been reported in the vessel wall and both fibroblasts and smooth muscle cells have been shown to produce elastase type enzymes in culture. Data is presented here showing that porcine aortic endothelial cells produce enzyme activities hydrolyzing elastin and synthetic substrates I Sue Ala Ala Ala nitroanilide, SAPNAI considered specific for elastase. Enzyme activity against the SAPNA but not against H-elastin was found to be associated with the cells after triton lysis .This activity was not secreted into the culture medium . The elastolytic activity has been partially characterized in relation to the kinetic of hydrolysis, pH optimum and susceptibility to different inhibitors. These studies revealed the presence of at least two enzymes: a metalo-protease with a pH optimum of 7.5 which accounts for approx. 80% of the total activity, and a serine protease with pH optimum of 8.0 which accounts for the remaining 20% . When the conditioned culture medium was studied, virtually no proteolytic activity could be detected even after activation with an organomercurial agent. However fractionation of the culture medium by gel filtration on HPLC resulted in elastolytic activity both against H-elastin and SAPNA. Proteolytic activity against casein could also be revealed after separation on SDS-PAGE. It is likely that these separation techniques remove an inhibitor also produced by the endothelial cells and allow the expression of proteolytic activity. That the elastolytic activity and the caseinolytic activity revealed by HPLC and PAGE respectively represent the activity of the same enzyme hase not yet been determined, and its relationship to the Stromelysin described by Herron et al(J. Biol. Chem. , 1986, 261. 2810-2813) in rabbit brain capillary endothelial cells is being investigated.
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Zebrowski, J., L. Jakubowski, M. J. Sadowski, K. Malinowski, M. Jakubowski, V. Weinzettl, J. Stockel, et al. "Diagnostics of Fast Electrons within Castor Tokamak by Means of a Modified Cherenkov-Type Probe." In PLASMA 2007: International Conference on Research and Applications of Plasmas; 4th German-Polish Conference on Plasma Diagnostics for Fusion and Applications; 6th French-Polish Seminar on Thermal Plasma in Space and Laboratory. AIP, 2008. http://dx.doi.org/10.1063/1.2909123.
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Voßnacke, Andre´, Wilhelm Graf, Roland Hu¨ggenberg, and Astrid Gisbertz. "Design, Loading, Transport and Storage Experience of CASTOR® Casks for Vitrified High Level Waste." In ASME 2003 9th International Conference on Radioactive Waste Management and Environmental Remediation. ASMEDC, 2003. http://dx.doi.org/10.1115/icem2003-4724.
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The revised German Atomic Act together with the Agreement between the German Government and the German Utilities of June 11, 2001 form new boundary conditions that considerably influence spent fuel strategies by stipulation of lifetime limitations to nuclear power plants and termination of reprocessing. The contractually agreed return of reprocessing residues comprises some 156 casks containing vitrified highly active waste, the so-called HAW or glass canisters, coming form irradiated nuclear fuel assemblies to be shipped from COGEMA, France and BNFL, UK to Germany presumably until 2011. Several hundred casks with compacted residues and other waste will follow. The transports are scheduled presumably beyond 2020. The central interim storage facilities in Ahaus and Gorleben, formerly intended to accumulate up to 8,000 t of heavy metal (HM) of spent fuel from German nuclear power plants, offer sufficient capacity to receive the totality of residues to be returned from reprocessing abroad. GNB has developed, tested, licensed, fabricated, loaded, transported and stored a large number of casks for spent fuel and is one of the world leaders for delivering spent fuel and high level waste casks. Long-term intermediate storage of spent fuel is carried out under dry conditions using these casks that are licensed for transport as well as for storage. Standardized high performance casks such as the types CASTOR® HAW 20/28 CG, CASTOR® V/19 and CASTOR® V/52 meet the needs of most nuclear power plants in Germany. Up to now GNS has co-ordinated the loading and transport of 27 casks loaded with 28 canisters each from COGEMA back to Germany for storage in Gorleben for up to 40 years. In all but one case the cask type CASTOR® HAW 20/28 CG has been used.
Звіти організацій з теми "Caslon type"
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Beckett-Brown, C. E., A. M. McDonald, and M. B. McClenaghan. Discovering a porphyry deposit using tourmaline: a case study from Yukon. Natural Resources Canada/CMSS/Information Management, 2023. http://dx.doi.org/10.4095/331349.
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As the exploration for porphyry Cu-Au-Mo deposits has become increasingly challenging, the development of more effective techniques directed at detecting buried deposits has become critical. One methodology is to focus on key minerals, one of which is tourmaline, a robust, ubiquitous mineral in most mineralized porphyry systems. Overall, a combination of physical and chemical characteristics including 1) macro-color, 2) morphology, 3) inclusion populations, and 4) trace-element compositions are useful in discriminating between porphyry- versus non-porphyry-derived (or related) tourmaline in surficial sediments (Beckett-Brown 2022). These features are applied to tourmaline obtained from stream sediment samples (n = 22) from 16 streams derived from the unglaciated terrain proximal to the Casino calc-alkaline porphyry Cu-Au-Mo deposit (Yukon Territory, Canada). The obtained tourmaline occurs as two distinct morphologies: 1) individual blocky to prismatic sub- to euhedral grains (Type 1), 2) aggregates of radiating prismatic to acicular sub- to euhedral grains (Type 2). Type 1 grains display trace-element contents that reflect mixed origins including a mineralized porphyry origin as well metamorphic and pegmatitic (background) environments. Type 2 grains almost exclusively exhibit porphyry-derived trace-element chemistries (i.e., high Sr/Pb ~150 avg. and relatively low Zn/Cu ~2.5 avg. values). In Canadian Creek, that directly drains from the Casino deposit, samples closest to the deposit contain >70% porphyry-derived tourmaline, while other streams in the region from unprospective drainage basins contain no porphyry-derived tourmaline. At the most distal sample site in Canadian Creek, ~20 km downstream from Casino, nearly 30% of the recovered tourmaline in the stream sediments is porphyry-related. This method has potential to be a strong indicator of prospectivity and applicable for exploration for porphyry Cu-Au-Mo systems in both unglaciated and glaciated terrains.
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Kidder, J. A., M. B. McClenaghan, M I Leybourne, M. W. McCurdy, P. Pelchat, D. Layton-Matthews, C. E. Beckett-Brown, and A. Voinot. Geochemical data for stream and groundwaters around the Casino Cu-Au-Mo porphyry deposit, Yukon (NTS 115 J/10 and 115 J/15). Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/328862.
Повний текст джерелаАнотація:
This open file reports geochemical data for stream and groundwater samples collected around the Casino porphyry Cu-Au-Mo deposit, one of the largest and highest-grade deposits of its kind in Canada. The calc-alkaline porphyry is hosted in a Late Cretaceous quartz monzonite and associated breccias in the unglaciated region of west central Yukon. Water chemistry around the deposit was investigated because: (i) the deposit has not yet been disturbed by mining; (ii) the deposit was known to have metal-rich waters in local streams; and (iii) the deposit has atypically preserved ore zones. Stream water samples were collected at 22 sites and groundwater samples were collected from eight sites. Surface and groundwaters around the Casino deposit are anomalous with respect to Cd (up to 5.4 µg/L), Co (up to 64 µg/L), Cu (up to 1657 µg/L), Mo (up to 25 µg/L), As (up to 17 µg/L), Re (up to 0.7 µg/L), and Zn (up to 354 µg/L) concentrations. The stable isotopes of O and H of the groundwaters are essentially identical to the surface waters and plot close to the local and global meteoric water lines, indicating that the waters represent modern recharge, consistent with the generally low salinities of all the waters (total dissolved solids range from 98 to 1320 mg/L). Sulfur and Sr isotopes are consistent with proximal waters interacting with the Casino rocks and mineralization; a sulfide-rich bedrock sample from the deposit has delta-34S = -1.2 permille and proximal groundwaters are only slightly heavier (-0.3 to 3.1 permille). These geochemical and isotopic results indicate that surface water geochemistry is a suitable medium for mineral exploration for porphyry-style mineralization in the Yukon, and similar unglaciated regions in Canada. The atypical geochemical signature (Mo, Se, Re, As, Cu) of these types of deposits are typically reflected in the water chemistry and S isotopes provide a more local vectoring tool.