Готові списки джерел за темами / Cardiac function analysis

Добірка наукової літератури з теми "Cardiac function analysis"

Автор: Grafiati
Опубліковано: 7 липня 2024

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  1. Статті в журналах
  2. Дисертації
  3. Книги
  4. Частини книг
  5. Тези доповідей конференцій
  6. Звіти організацій

Статті в журналах з теми "Cardiac function analysis":

1

Yambe, T., S. Nanka, S. Kobayashi, N. Owada, A. Ozoe, A. Miyakawa, S. Konno, et al. "NONLINEAR ANALYSIS OF CARDIAC CONTRACTION TO EVALUATE THE CARDIAC FUNCTION." ASAIO Journal 45, no. 2 (March 1999): 146. http://dx.doi.org/10.1097/00002480-199903000-00107.

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2

Guttman, M. A., E. A. Zerhouni, and E. R. McVeigh. "Analysis of cardiac function from MR images." IEEE Computer Graphics and Applications 17, no. 1 (January 1997): 30–38. http://dx.doi.org/10.1109/38.576854.

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3

SEI, Tetsurou. "Quantitative analysis of cardiac function using cine MR." Okayama Igakkai Zasshi (Journal of Okayama Medical Association) 106, no. 1-2 (1994): 163–71. http://dx.doi.org/10.4044/joma1947.106.1-2_163.

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4

Araki, Junichi, Hiromi Matsubara, Juichiro Shimizu, Takeshi Mikane, Satoshi Mohri, Ju Mizuno, Miyako Takaki, Tohru Ohe, Masahisa Hirakawa, and Hiroyuki Suga. "Weibull distribution function for cardiac contraction: integrative analysis." American Journal of Physiology-Heart and Circulatory Physiology 277, no. 5 (November 1, 1999): H1940—H1945. http://dx.doi.org/10.1152/ajpheart.1999.277.5.h1940.

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The Weibull distribution is widely used to analyze the cumulative loss of performance, i.e., breakdown, of a complex system in systems engineering. We found for the first time that the difference curve of two Weibull distribution functions almost identically fitted the isovolumically contracting left ventricular (LV) pressure-time curve [P( t)] in all 345 beats (3 beats at each of 5 volumes in 23 canine hearts; r = 0.999953 ± 0.000027; mean ± SD). The first derivative of the difference curve also closely fitted the first derivative of the P( t) curve. These results suggest the possibility that the LV isovolumic P( t) curve may be characterized by two counteracting cumulative breakdown systems. Of these, the first breakdown system causes a gradual pressure rise and the second breakdown system causes a gradual pressure fall. This Weibull-function model of the heart seems to give a new systems engineering or integrative physiological view of the logic underlying LV isovolumic pressure generation.
5

ROBERTS, N., L. M. CRUZ‐ORIVE, M. BOURNE, R. J. HERFKENS, R. A. KARWOSKI, and G. H. WHITEHOUSE. "Analysis of cardiac function by MRI and stereology." Journal of Microscopy 187, no. 1 (July 1997): 31–42. http://dx.doi.org/10.1046/j.1365-2818.1997.2040764.x.

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6

Hunter, P. J., and B. H. Smaill. "The analysis of cardiac function: A continuum approach." Progress in Biophysics and Molecular Biology 52, no. 2 (January 1988): 101–64. http://dx.doi.org/10.1016/0079-6107(88)90004-1.

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7

Gajewski, K., N. Fossett, J. D. Molkentin, and R. A. Schulz. "The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila." Development 126, no. 24 (December 15, 1999): 5679–88. http://dx.doi.org/10.1242/dev.126.24.5679.

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The regulation of cardiac gene expression by GATA zinc finger transcription factors is well documented in vertebrates. However, genetic studies in mice have failed to demonstrate a function for these proteins in cardiomyocyte specification. In Drosophila, the existence of a cardiogenic GATA factor has been implicated through the analysis of a cardial cell enhancer of the muscle differentiation gene D-mef2. We show that the GATA gene pannier is expressed in the dorsal mesoderm and required for cardial cell formation while repressing a pericardial cell fate. Ectopic expression of Pannier results in cardial cell overproduction, while co-expression of Pannier and the homeodomain protein Tinman synergistically activate cardiac gene expression and induce cardial cells. The related GATA4 protein of mice likewise functions as a cardiogenic factor in Drosophila, demonstrating an evolutionarily conserved function between Pannier and GATA4 in heart development.
8

Snelling, Edward P., Roger S. Seymour, J. E. F. Green, Leith C. R. Meyer, Andrea Fuller, Anna Haw, Duncan Mitchell, et al. "A structure-function analysis of the left ventricle." Journal of Applied Physiology 121, no. 4 (October 1, 2016): 900–909. http://dx.doi.org/10.1152/japplphysiol.00435.2016.

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This study presents a structure-function analysis of the mammalian left ventricle and examines the performance of the cardiac capillary network, mitochondria, and myofibrils at rest and during simulated heavy exercise. Left ventricular external mechanical work rate was calculated from cardiac output and systemic mean arterial blood pressure in resting sheep ( Ovis aries; n = 4) and goats ( Capra hircus; n = 4) under mild sedation, followed by perfusion-fixation of the left ventricle and quantification of the cardiac capillary-tissue geometry and cardiomyocyte ultrastructure. The investigation was then extended to heavy exercise by increasing cardiac work according to published hemodynamics of sheep and goats performing sustained treadmill exercise. Left ventricular work rate averaged 0.017 W/cm3 of tissue at rest and was estimated to increase to ∼0.060 W/cm3 during heavy exercise. According to an oxygen transport model we applied to the left ventricular tissue, we predicted that oxygen consumption increases from 195 nmol O2·s−1·cm−3 of tissue at rest to ∼600 nmol O2·s−1·cm−3 during heavy exercise, which is within 90% of the oxygen demand rate and consistent with work remaining predominantly aerobic. Mitochondria represent 21-22% of cardiomyocyte volume and consume oxygen at a rate of 1,150 nmol O2·s−1·cm−3 of mitochondria at rest and ∼3,600 nmol O2·s−1·cm−3 during heavy exercise, which is within 80% of maximum in vitro rates and consistent with mitochondria operating near their functional limits. Myofibrils represent 65–66% of cardiomyocyte volume, and according to a Laplacian model of the left ventricular chamber, generate peak fiber tensions in the range of 50 to 70 kPa at rest and during heavy exercise, which is less than maximum tension of isolated cardiac tissue (120–140 kPa) and is explained by an apparent reserve capacity for tension development built into the left ventricle.
9

Cingolani, Oscar H., and David A. Kass. "Pressure-volume relation analysis of mouse ventricular function." American Journal of Physiology-Heart and Circulatory Physiology 301, no. 6 (December 2011): H2198—H2206. http://dx.doi.org/10.1152/ajpheart.00781.2011.

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Nearly 40 years ago, the Sagawa laboratory spawned a renaissance in the use of instantaneous ventricular pressure-volume (P-V) relations to assess cardiac function. Since then, this analysis has taken hold as the most comprehensive way to quantify ventricular chamber function and energetics and cardiovascular interactions. First studied in large mammalian hearts and later in humans employing a catheter-based method, P-V analysis was translated to small rodents in the late 1990s by the Kass laboratory. Over the past decade, this approach has become a gold standard for comprehensive examination of in vivo cardiac function in mice, facilitating a new era of molecular cardiac physiology. The catheter-based method remains the most widely used approach in mice. In this brief review, we discuss this instrumentation, the theory behind its use, and how volume signals are calibrated and discuss elements of P-V analysis. The goal is to provide a convenient summary of earlier investigations and insights for users whose primary interests lie in genetic/molecular studies rather than in biomedical engineering.
10

Yuasa, Toshinori, Mihoko Kouno, Akira Kisanuki, Nami Ueya, Kenichi Nakashiki, Eiji Kuwahara, Kayoko Kubota, Naoko Mizukami, Kunitsugu Takasaki, and Chuwa Tei. "Assessment of Cardiac Function and Heart Failure by Cardiac Time Analysis (Tei Index)." Journal of Cardiac Failure 15, no. 7 (September 2009): S138. http://dx.doi.org/10.1016/j.cardfail.2009.07.219.

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Статті в журналах Дисертації Книги

Дисертації з теми "Cardiac function analysis":

1

Wang, Haiyan. "Cardiac motion and function analysis using MR imaging." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/30717.

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Cardiacvascular disease (CVD) is the single leading cause of death in the world, claiming 17.3 million lives a year according to the World Health Organisation (WHO). The development of magnetic resonance (MR) imaging has provided clinicians and researchers with effective tools to detect, assess and monitor the progress of the disease and treatments. MR imaging produces images with high spatial resolution using noninvasive and non-ionising techniques. However, quantitative analysis of the cardiovascular system from MR images remains challenging. The work presented in this thesis focuses on the utilization of cardiac motion information including motion tracking, quantification of the motion and prediction of clinical variables by incorporating motion information. The first main contributions of the thesis are approaches for sparse and dense motion tracking: a sparse set of key landmarks is detected and tracked. They are used as constraints to perform cardiac dense motion tracking using both 3D tagged and untagged image sequences from short-axis and long-axis MR views simultaneously. In order to improve speed and accuracy of the motion tracking, we also develop an approach to identify and track a sparse set of distinctive landmarks in the presence of relatively large deformations for myocardium motion tracking without applying dense motion tracking. An integrated framework is proposed to combine entropy and SVD-based sparse landmark detection with a MRF-based motion tracking framework. In addition, the regional wall thickness systolic dyssynchrony index (SDI) derived directly from sparse motion tracking provides accurate quantification of LV motion, which agrees well with the clinical measurements. In our last contribution, we successfully used manifold learning as a feature selection approach for a SVM-based classification and regression to analyse 209 cardiac MR image sequences. The SVM-based approaches directly operate on the manifold coordinates of the MR images without requiring any non-rigid registration or segmentation and is hence computationally efficient. We demonstrate that, by considering both inter- and intra-subject variation in the manifold learning, we are able to extract both anatomical and functional information. This can be used to construct powerful and reliable classifiers that are more predictive than global indices such as LV volume and mass. The manifold allows for investigating how much temporal information is needed improve the classification performance. The regression experiments demonstrate that there is a very strong correlation between manifold coordinates and obesity indices.
2

Piva, Rosa Maria Volpi. "Analysis and visualization of cardiac wall motion from magnetic resonance images." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246777.

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3

Prakosa, Adityo. "Analysis and simulation of multimodal cardiac images to study the heart function." Phd thesis, Université Nice Sophia Antipolis, 2013. http://tel.archives-ouvertes.fr/tel-00837857.

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This thesis focuses on the analysis of the cardiac electrical and kinematic function for heart failure patients. An expected outcome is a set of computational tools that may help a clinician in understanding, diagnosing and treating patients suffering from cardiac motion asynchrony, a specific aspect of heart failure. Understanding the inverse electro-kinematic coupling relationship is the main task of this study. With this knowledge, the widely available cardiac image sequences acquired non-invasively at clinics could be used to estimate the cardiac electrophysiology (EP) without having to perform the invasive cardiac EP mapping procedures. To this end, we use real clinical cardiac sequence and a cardiac electromechanical model to create controlled synthetic sequence so as to produce a training set in an attempt to learn the cardiac electro-kinematic relationship. Creating patient-specific database of synthetic sequences allows us to study this relationship using a machine learning approach. A first contribution of this work is a non-linear registration method applied and evaluated on cardiac sequences to estimate the cardiac motion. Second, a new approach in the generation of the synthetic but virtually realistic cardiac sequence which combines a biophysical model and clinical images is developed. Finally, we present the cardiac electrophysiological activation time estimation from medical images using a patient-specific database of synthetic image sequences.
4

Shi, Wenzhe. "An image segmentation and registration approach to cardiac function analysis using MRI." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/10548.

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Cardiovascular diseases (CVDs) are one of the major causes of death in the world. In recent years, significant progress has been made in the care and treatment of patients with such diseases. A crucial factor for this progress has been the development of magnetic resonance (MR) imaging which makes it possible to diagnose and assess the cardiovascular function of the patient. The ability to obtain high-resolution, cine volume images easily and safely has made it the preferred method for diagnosis of CVDs. MRI is also unique in its ability to introduce noninvasive markers directly into the tissue being imaged(MR tagging) during the image acquisition process. With the development of advanced MR imaging acquisition technologies, 3D MR imaging is more and more clinically feasible. This recent development has allowed new potentially 3D image analysis technologies to be deployed. However, quantitative analysis of cardiovascular system from the images remains a challenging topic. The work presented in this thesis describes the development of segmentation and motion analysis techniques for the study of the cardiac anatomy and function in cardiac magnetic resonance (CMR) images. The first main contribution of the thesis is the development of a fully automatic cardiac segmentation technique that integrates and combines a series of state-of-the-art techniques. The proposed segmentation technique is capable of generating an accurate 3D segmentation from multiple image sequences. The proposed segmentation technique is robust even in the presence of pathological changes, large anatomical shape variations and locally varying contrast in the images. Another main contribution of this thesis is the development of motion tracking techniques that can integrate motion information from different sources. For example, the radial motion of the myocardium can be tracked easily in untagged MR imaging since the epi- and endocardial surfaces are clearly visible. On the other hand, tagged MR imaging allows easy tracking of both longitudinal and circumferential motion. We propose a novel technique based on non-rigid image registration for the myocardial motion estimation using both untagged and 3D tagged MR images. The novel aspect of our technique is its simultaneous use of complementary information from both untagged and 3D tagged MR imaging. The similarity measure is spatially weighted to maximise the utility of information from both images. The thesis also proposes a sparse representation for free-form deformations (FFDs) using the principles of compressed sensing. The sparse free-form deformation (SFFD) model can capture fine local details such as motion discontinuities without sacrificing robustness. We demonstrate the capabilities of the proposed framework to accurately estimate smooth as well as discontinuous deformations in 2D and 3D CMR image sequences. Compared to the standard FFD approach, a significant increase in registration accuracy can be observed in datasets with discontinuous motion patterns. Both the segmentation and motion tracking techniques presented in this thesis have been applied to clinical studies. We focus on two important clinical applications that can be addressed by the techniques proposed in this thesis. The first clinical application aims at measuring longitudinal changes in cardiac morphology and function during the cardiac remodelling process. The second clinical application aims at selecting patients that positively respond to cardiac resynchronization therapy (CRT). The final chapter of this thesis summarises the main conclusions that can be drawn from the work presented here and also discusses possible avenues for future research.
5

Rehmani, Taha. "An In-vivo Analysis of SLMAP Function in the Postnatal Mouse Myocardium." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36666.

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SLMAP is a tail anchored membrane protein that alternatively splices to generate three isoforms, SLMAP1, SLMAP2 and SLMAP3. Previous studies in our lab have shown that the postnatal cardiac-specific overexpression of SLMAP1 results in intracellular vesicle expansion and enhanced endosomal recycling. I generated a postnatal cardiac-specific knockout model using the Cre-Lox system to nullify all three SLMAP isoforms and further evaluate its role in the mouse myocardium. SLMAP knockdown and knockout mouse hearts were analyzed with western blotting and qPCR. I found that only SLMAP3 was nullified and phenotypic evaluation through echocardiography indicated that young and old SLMAP3 knockout animals showed no remarkable changes in cardiac function. Furthermore, challenge with stressor isoproterenol had a similar response to wildtype and knockout mice in cardiac structure and function. Surprisingly the level of expression of SLMAP1 and SLMAP2 was maintained in the myocardium from SLMAP3 deficient mice. Interestingly the machinery involved in endosomal recycling was not impacted by the loss of SLMAP3. These data indicate that loss of SLMAP3 does not alter cardiac structure and function in the postnatal myocardium in the presence of SLMAP1 and SLMAP2.
6

Vigneault, Davis Marc. "Quantification of regional cardiac function : clinically-motivated algorithm development and application to cardiac magnetic resonance and computed tomography." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:b158793e-5f68-4aad-9335-f143e5864886.

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Techniques described to date for the reproducible and noninvasive quantification of regional cardiac function have been largely relegated to research settings due to time-consuming and cumbersome image acquisition and analysis. In this thesis, feature tracking algorithms are developed for 2-D+Time cardiac magnetic resonance (CMR) and 3-D+Time cardiac computed tomography (CCT) image sequences that are easily acquired clinically, while emphasising reproducibility and automation in their design. First, a commercially-implemented CMR feature tracking algorithm for the analysis of steady state free precession (SSFP) cine series is evaluated in patients with hypertrophic cardiomyopathy (HCM) and arrhythmogenic right ventricular cardiomyopathy (ARVC), which primarily affect the left ventricle (LV) and right ventricle (RV), respectively, and functional impairment compared with control populations is found in both cases. The limitations of this implementation are then used to guide development of an automated algorithm for the same purpose, making use of fully convolutional neural networks (CNN) for segmentation and spline registration across all frames simultaneously for tracking. This study is performed in the subjects with HCM, and functional impairment is again identified in disease subjects. Finally, as myocardial contraction is inherently a 3-D phenomenon, a technique is developed for quantification of regional function from 3-D+Time functional CCT studies using simultaneous registration of automatically generated Loop subdivision surface models for tracking. This study is performed in canine mongrels, and compared with the current state of the art technique for CCT functional analysis. This work demonstrates the feasibility of automated, reproducible cardiac functional analysis from CMR and CCT image sequences. While work remains to be done in extending the principles demonstrated and modular components described to fully automated whole-heart analysis, it is hoped that this thesis will accelerate the clinical adoption of regional functional analysis.
7

Grunert, Marcel [Verfasser]. "Computational analysis of next-generation sequencing data in cardiac function and disease / Marcel Grunert." Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1029963150/34.

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8

Ahlsson, Anders. "Atrial fibrillation in cardiac surgery." Doctoral thesis, Örebro universitet, Hälsoakademin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-2442.

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Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice. In cardiac surgery, one-third of the patients experience episodes of AF during the first postoperative days (postoperative AF), and patients with preoperative AF (concomitant AF) can be offered ablation procedures in conjunction with surgery, in order to restore ordinary sinus rhythm (SR). The aim of this work was to study the relation between postoperative AF and inflammation; the long-term consequences of postoperative AF on mortality and late arrhythmia; and atrial function after concomitant surgical ablation for AF. In 524 open-heart surgery patients, C-reactive protein (CRP) serum concentrations were measured before and on the third day after surgery. There was no correlation between levels of CRP and the development of postoperative AF. All 1,419 patients with no history of AF, undergoing primary aortocoronary bypass surgery (CABG) in the years 1997–2000 were followed up after 8.0 years. The mortality rate was 191 deaths/1,000 patients (19.1%) in patients with no AF and 140 deaths/419 patients (33.4%) in patients with postoperative AF. Postoperative AF was an age-independent risk factor for late mortality, with a hazard ratio (HR) of 1.56 (95% CI 1.23–1.98). Postoperative AF patients had a more than doubled risk of death due to cerebral ischaemia, myocardial infarction, sudden death, and heart failure compared with patients without AF. All 571 consecutive patients undergoing primary CABG during the years 1999–2000 were followed-up after 6 years. Questionnaires were obtained from 91.6% of surviving patients and an electrocardiogram (ECG) from 88.3% of all patients. In postoperative AF patients, 14.1% had AF at follow-up, compared with 2.8% of patients with no AF at surgery (p<.001). An episode of postoperative AF was found to be an independent risk factor for development of late AF, with an adjusted risk ratio (RR) of 3.11 (95% CI 1.41–6.87). Epicardial microwave ablation was performed in 20 open-heart surgery patients with concomitant AF. Transthoracic echocardiography was performed preoperatively and at 6 months postoperatively. At 12 months postoperatively 14/19 patients (74%) were in SR with no anti-arrhythmic drugs. All patients in SR had preserved left and right atrial filling waves (A-waves) and Tissue velocity echocardiography (TVE) showed preserved atrial wall velocities and atrial strain. In conclusion, postoperative AF is an independent risk factor for late mortality and later development of AF. There is no correlation between the inflammatory marker CRP and postoperative AF. Epicardial microwave ablation of concomitant AF results in SR in the majority of patients and seems to preserve atrial mechanical function.
9

Cloud, Jennifer Ellen 1976. "Genetic and molecular analysis of the E2F transcription factor family in mouse development, tumorigenesis, and cardiac function." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/29593.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2003.
Includes bibliographical references.
The E2F transcription factors are critical downstream targets of the retinoblastoma protein (pRB) pathway. A component of the pRB pathway is mutated in most human tumors resulting in deregulation of cell cycle control through the inappropriate release of E2Fs. E2F1, E2F2, and E2F3 are members of the "activating E2F" subfamily that is important for the transcriptional activation of target genes involved in DNA replication and cell cycle control. These E2F family members are essential for cellular proliferation in vitro. This study analyzes the role of the activating E2Fs in vivo using mutant mouse models. It demonstrates that E2F3 is essential for viability in a strain dependent manner. E2f3 animals die at three distinct time points from cardiac etiologies. The embryonic and neonatal lethality of these animals is consistent with proliferation defects in the myocardium that result in hypoplastic heart walls and septa. E2f animals that survive the perinatal period eventually die from highly penetrant, late-onset congestive heart failure. This is the first evidence that proliferation regulators have an important role in adult heart failure. In addition, this study examines the relative roles of E2F1 and E2F3 in vivo. It shows that E2F1 and E2F3 have functional overlap during mouse development as well as in the maintenance of a number of adult tissues. However, E2F1 appears to have a distinct function as a tumor suppressor gene. Importantly, E2F1 and E2F3 both contribute to normal cardiac function. Furthermore, mutation of the gene for the pRB protein that negatively regulates the activating E2Fs can rescue the heart failure in the E2f3 animals. These data argue strongly that proper regulation of proliferation is critical for adult cardiac function.
by Jennifer Ellen Cloud.
Ph.D.
10

Kaniewska, Malwina [Verfasser]. "Noninvasive evaluation of cardiac function using Computed Tomography and Magnetic Resonance Imaging : a meta-analysis / Malwina Kaniewska." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1140486861/34.

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Книги з теми "Cardiac function analysis":

1

Paul, Richard, and Paul Grant. Blood gas analysis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0018_update_001.

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Acid-base homeostasis is vital for the maintenance of normal tissue and organ function, as both acidosis and alkalosis can have harmful and potentially life-threatening effects. Arterial blood gas analysis, combined with routine clinical history and examination, can provide useful information for the management of the critically ill cardiac patient. Most acid-base derangements are reversed by treatment of the underlying disease process, rather than simple correction of the abnormal pH, and prognosis is determined by the nature of the underlying disease, rather than the extent of pH value deviation. Within this chapter, a six-step approach is presented for prompt and accurate acid-base interpretation. Water and electrolyte disorders are common in the intensive cardiac care unit, particularly in patients with cardiac failure. Prompt recognition and treatment is required to prevent cardiovascular and neurological compromise. Therapeutic strategies range from simple electrolyte substitution and fluid management to extracorporeal filtration of excess fluid and electrolytes. These are discussed within this chapter.
2

Lancellotti, Patrizio, and Bernard Cosyns. Assessment of Diastolic Function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713623.003.0005.

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Diastole is the part of the cardiac cycle starting at aortic valve closure and ending at mitral valve closure. Evaluation of diastolic function by echocardiography is useful to diagnose heart failure with preserved ejection fraction, and regardless of ejection fraction, echocardiography can be used to estimate left ventricular filling pressure. Assessment of diastolic function includes analysis of left ventricular relaxation and compliance, left atrial and left ventricular filling pressures. This chapter describes the phases of diastole and covers the integrated approach of LV diastolic function through M-Mode and 2D/3D echocardiography, pulsed-wave Doppler echocardiography, and pulsed-wave tissue Doppler echocardiography.
3

De Deyne, Cathy, and Jo Dens. Neurological assessment of the acute cardiac care patient. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0016.

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Many techniques are currently available for cerebral physiological monitoring in the intensive cardiac care unit environment. The ultimate goal of cerebral monitoring applied during the acute care of any patient with/or at risk of a neurological insult is the early detection of regional or global hypoxic/ischaemic cerebral insults. In the most ideal situation, cerebral monitoring should enable the detection of any deterioration before irreversible brain damage occurs or should at least enable the preservation of current brain function (such as in comatose patients after cardiac arrest). Most of the information that affects bedside care of patients with acute neurologic disturbances is now derived from clinical examination and from knowledge of the pathophysiological changes in cerebral perfusion, cerebral oxygenation, and cerebral function. Online monitoring of these changes can be realized by many non-invasive techniques, without neglecting clinical examination and basic physiological variables such as invasive arterial blood pressure monitoring or arterial blood gas analysis.
4

De Deyne, Cathy, Ward Eertmans, and Jo Dens. Neurological assessment of the acute cardiac care patient. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0016_update_001.

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Many techniques are currently available for cerebral physiological monitoring in the intensive cardiac care unit environment. The ultimate goal of cerebral monitoring applied during the acute care of any patient with/or at risk of a neurological insult is the early detection of regional or global hypoxic/ischaemic cerebral insults. In the most ideal situation, cerebral monitoring should enable the detection of any deterioration before irreversible brain damage occurs or should at least enable the preservation of current brain function (such as in comatose patients after cardiac arrest). Most of the information that affects bedside care of patients with acute neurologic disturbances is now derived from clinical examination and from knowledge of the pathophysiological changes in cerebral perfusion, cerebral oxygenation, and cerebral function. Online monitoring of these changes can be realized by many non-invasive techniques, without neglecting clinical examination and basic physiological variables—with possible impact on optimal cerebral perfusion/oxygenation—such as invasive arterial blood pressure monitoring or arterial blood gas analysis.
5

Paul, Richard, Pavlos Myrianthefs, George Baltopoulos, and Shaun McMaster. Blood gas analysis: acid–base, fluid, and electrolyte disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0018.

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Acid-base homeostasis is vital for the maintenance of normal tissue and organ function, as both acidosis and alkalosis can have harmful and potentially life-threatening effects. Arterial blood gas analysis, combined with routine clinical history and examination, can provide useful information for the management of the critically ill cardiac patient. Most acid-base derangements are reversed by treatment of the underlying disease process, rather than simple correction of the abnormal pH, and prognosis is determined by the nature of the underlying disease, rather than the extent of pH value deviation. Within this chapter, a six-step approach is presented for prompt and accurate acid-base interpretation. Water and electrolyte disorders are common in the intensive cardiac care unit, particularly in patients with cardiac failure. Prompt recognition and treatment is required to prevent cardiovascular and neurological compromise. Therapeutic strategies range from simple electrolyte substitution and fluid management to extracorporeal filtration of excess fluid and electrolytes. These are discussed within this chapter.
6

Monaghan, M., and S. Adhya. Three dimensional echocardiography. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0003.

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Three-dimensional (3D) echocardiography allows the real-time acquisition of volumes containing entire cardiac structures. The analysis of 3D volumes does not require any assumptions as to the shape of structures.3D echocardiography is more accurate than two-dimensional (2D) in the assessment of left ventricular (LV) volumes, mass, and function, and is comparable to cardiac magnetic resonance imaging. This makes it an ideal modality for measuring LV function particularly when this will determine significant interventions such as implanting of cardioverter/defibrillators, biventricular pacing, and the commencement and continuation of cancer chemotherapy. 3D echocardiography makes it easy to visualize valves and define pathological mechanisms. 3D assessment of dyssynchrony, myocardial strain, and stress imaging are attractive.However, 3D echocardiography is limited by the need for specialist software and lower spatial and temporal resolution when compared to 2D echocardiography.
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Ruiz-Villalba, Adrián, Nikolaos Frangogiannis, and José Maria Pérez-Pomares. Origin and diversity of cardiac fibroblasts: developmental substrates of adult cardiac fibrosis. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, José Luis de la Pompa, David Sedmera, Cristina Basso, and Deborah Henderson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0012.

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Cardiac connective tissues are primarily formed by cardiac fibroblasts (CF) of diverse embryonic origins. Whereas CF specific roles in cardiac morphogenesis remain under-researched, their involvement in adult cardiac fibrosis is clinically relevant. Cardiac fibrosis is a common element of several chronic cardiac conditions characterized by the loss of ventricular wall mechanical function, ultimately driving to heart failure. In the ischaemic heart early reparative fibrosis evidences the very restricted regenerative potential of the myocardium. In non-ischaemic diseases fibrosis is activated by unknown signals. We summarize current knowledge on the origin of CFs and their developmental roles, and discuss the differential disease-dependent response of different CF subpopulations to various pathological stimuli. We also describe the characteristic cell-cell and cell-matrix interactions that determine the fibrotic remodelling of the myocardium. We analyse experimental models for the study of cardiac fibrosis, and suggest future directions in the search for new markers and therapeutic targets.
8

De Bono, Christopher, Magali Théveniau-Ruissy, and Robert G. Kelly. Cardiac fields and myocardial cell lineages. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, José Luis de la Pompa, David Sedmera, Cristina Basso, and Deborah Henderson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0004.

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We focus on the origin of myocardial cells in the first and second heart fields in splanchnic mesoderm in the early embryo. Genetic lineage tracing using Cre recombinase activated conditional reporter genes has made a major contribution to our understanding of cardiac progenitor cells and will be discussed together with other experimental approaches to analysing cell lineages at the clonal level. Interactions between myocardial, epicardial and endocardial lineages are essential for coordinated function and homeostasis of the normal heart. Perturbation of heart field development and myocardial lineage contributions to the heart through developmental or acquired pathologies results in and modulates the progression of cardiac disease. Understanding the origin of myocardial lineages during embryonic development and how they converge to generate an integrated heart is thus a major biomedical objective. Furthermore, reactivation of developmental programmes is likely to be of major importance in strategies aimed at repair of the damaged heart.
9

Prout, Jeremy, Tanya Jones, and Daniel Martin. Cardiovascular system. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0001.

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This chapter covers the assessment and investigation of perioperative cardiac risk, the principles of perioperative haemodynamic monitoring and physiological changes in cardiac comorbidity with their relevance to anaesthetic management. Perioperative cardiovascular risk includes assessment of cardiac risk factors, functional capacity and evidence-based guidelines for preassessment. Cardiovascular investigations such as cardiopulmonary exercise testing and scoring systems for cardiac risk are included. Management of the cardiac patient for non-cardiac surgery is detailed. Invasive monitoring with arterial, central venous and pulmonary artery catheters is described. Cardiac output measurement systems including dilution techniques, pulse contour analysis and Doppler are compared. The physiological changes, management and implications for anaesthesia of common cardiac comorbidity including ischaemic heart disease, heart failure, valvular heart disease, pacemakers and pulmonary hypertension are described.
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Voigt, Jens Uwe, Peter Søgaard, and Emer Joyce. Heart failure: left ventricular dyssynchrony. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0026.

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Echocardiography plays a pivotal role in the management of patients with dilative cardiomyopathy and conduction disease, particularly in the setting of cardiac resynchronization therapy (CRT). Current CRT guidelines recommend the echocardiographic assessment of left ventricular size and function. Furthermore, echocardiography has the potential of analysing regional myocardial mechanics with high temporal resolution and without radiation burden or danger for the patient. Assessment of left ventricular dyssynchrony has therefore become the next challenge. Besides the visual approaches, newer methods of functional imaging such as tissue Doppler and speckle tracking allow the exact quantification of regional myocardial function. This chapter reviews the current status of left ventricular dyssynchrony assessment by echocardiography and introduces emerging techniques which can better link conduction abnormalities and mechanical events and, thus, potentially improve clinical decision-making in this field.
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Частини книг з теми "Cardiac function analysis":

1

Mancini, G. B. John, Andrew J. Buda, and Charles B. Higgins. "The analysis of left ventricular function with digital subtraction angiography." In Digital Cardiac Imaging, 84–105. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4996-6_7.

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2

Abd-Elmoniem, Khaled Z., and Jerry Prince. "Algorithms for Real-Time FastHARP Cardiac Function Analysis." In Lecture Notes in Computer Science, 516–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-540-39899-8_64.

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3

Escalona-Morán, M., A. Hernández, R. Medina, and M. Garreau. "Model-based image analysis of the cardiac function." In IV Latin American Congress on Biomedical Engineering 2007, Bioengineering Solutions for Latin America Health, 329–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-74471-9_76.

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4

Rosenbaum, David S. "Microvolt-Level T-Wave Alternans as a Marker of Vulnerability to Cardiac Arrhythmias: Principles and Detection Methods." In Analysis and Assessment of Cardiovascular Function, 299–323. New York, NY: Springer New York, 1998. http://dx.doi.org/10.1007/978-1-4612-1744-2_18.

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5

Rankin, J. Scott, Joseph R. Elbeery, John C. Lucke, William Gaynor, David H. Harpole, Michael P. Feneley, Srdjan Nikolić, et al. "An Energetic Analysis of Myocardial Performance." In Cardiac Mechanics and Function in the Normal and Diseased Heart, 165–88. Tokyo: Springer Japan, 1989. http://dx.doi.org/10.1007/978-4-431-67957-8_17.

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6

Alpert, N. R., B. J. Leavitt, F. P. Ittleman, G. Hasenfuss, B. Pieske, and L. A. Mulieri. "A mechanistic analysis of the force-frequency relation in non-failing and progressively failing human myocardium." In Heart rate as a determinant of cardiac function, 37–52. Heidelberg: Steinkopff, 2000. http://dx.doi.org/10.1007/978-3-642-47070-7_2.

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7

McLeod, Kristin, Christof Seiler, Maxime Sermesant, and Xavier Pennec. "A Near-Incompressible Poly-affine Motion Model for Cardiac Function Analysis." In Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges, 288–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36961-2_33.

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8

Lam, Hoi-Ieng, Brett R. Cowan, Martyn P. Nash, and Alistair A. Young. "Interactive Cardiac Image Analysis for Biventricular Function of the Human Heart." In Statistical Atlases and Computational Models of the Heart, 144–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-15835-3_15.

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9

Kerkhof, Peter L. M., Richard A. Peace, Guy R. Heyndrickx, Lilian J. Meijboom, Ralf W. Sprengers, and Neal Handly. "Heart Function Analysis in Cardiac Patients with Focus on Sex-Specific Aspects." In Advances in Experimental Medicine and Biology, 361–77. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-77932-4_23.

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10

Shi, Pengcheng, and Huafeng Liu. "Stochastic Finite Element Framework for Cardiac Kinematics Function and Material Property Analysis." In Medical Image Computing and Computer-Assisted Intervention — MICCAI 2002, 634–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45786-0_78.

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Тези доповідей конференцій з теми "Cardiac function analysis":

1

Thompson, M. A., D. A. Ortendahl, W. W. Holt, and C. B. Higgins. "Cardiac function analysis with low field magnetic resonance imaging." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.94542.

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2

Abd-Elmoniem, Klaled Z., Smita Sampath, Nael F. Osman, and Jerry L. Prince. "Tool for automatic real-time regional cardiac function analysis using HARP." In Medical Imaging 2003, edited by Robert L. Galloway, Jr. SPIE, 2003. http://dx.doi.org/10.1117/12.479763.

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3

Bijnens, B., P. Claus, C. Parsai, M. Cikes, S. Loncaric, L. Anderson, and G. R. Sutherland. "An integrated framework for the assessment of cardiac function - Description and illustrated applications." In 2007 5th International Symposium on Image and Signal Processing and Analysis. IEEE, 2007. http://dx.doi.org/10.1109/ispa.2007.4383714.

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4

Kalinic, H., S. Loncaric, M. Cikes, A. Baltabaeva, C. Parsai, J. Separovic, I. Cikes, G. R. Sutherland, and B. Bijnens. "Analysis of Doppler Ultrasound Outflow Profiles for the Detection of changes in Cardiac Function." In 2007 5th International Symposium on Image and Signal Processing and Analysis. IEEE, 2007. http://dx.doi.org/10.1109/ispa.2007.4383713.

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5

Blagosklonov, Oleg, Remy Sabbah, Pascal Berthout, Laurent Comas, Josette Verdenet, Michel Baud, and Jean-Claude Cardot. "Karhunen-Loeve transform for analysis of cardiac function in myocardial gated SPECT." In Medical Imaging 2003, edited by Milan Sonka and J. Michael Fitzpatrick. SPIE, 2003. http://dx.doi.org/10.1117/12.480300.

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6

Duan, Q., S. Homma, and A. F. Laine. "P2A-9 Analysis of 4D Ultrasound for Dynamic Measures of Cardiac Function." In 2007 IEEE Ultrasonics Symposium Proceedings. IEEE, 2007. http://dx.doi.org/10.1109/ultsym.2007.375.

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7

Benameur, Narjes, Tarek Kraiem, Younes Arous, and Nejmeddine ben Abdallah. "Quantitative analysis of myocardial motion in cardiac magnetic resonance imaging using covariance function." In 2017 International Conference on Engineering & MIS (ICEMIS). IEEE, 2017. http://dx.doi.org/10.1109/icemis.2017.8272978.

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8

Delgado Ortiz, Laura, Ane Arbillaga-Etxarri, Diego Rodríguez, Elena Gimeno-Santos, Anael Barberan-Garcia, Robert Rodríguez-Roisin, Eva Balcells, Jordi Vilaró, and Judith Garcia-Aymerich. "Physical activity and cardiac autonomic function in patients with COPD, a cross-sectional analysis." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2436.

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9

Stute, F., L. Mamudi, M. Nickel, C. Schwering, J. Olfe, A. Schulz, R. Kozlik-Feldmann, and P. Schneider. "Prospective Analysis of Cardiac Function in Patients with CLN2 Disease: Do We Need a Different Management Because of Cardiac Co-morbidities." In 56th Annual Meeting of the German Society for Pediatric Cardiology (DGPK). Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1780770.

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10

Menon, Prahlad G., and Srilakshmi M. Adhyapak. "Shape Analysis for Automatic and Objective Visualization of Pathological Cardiovascular Remodeling From Cine Cardiac MRI." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14078.

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Normal cardiovascular tissue structure and therefore shape is governed by an equilibrium existing between stimulator and inhibitor signals that regulate growth and remodeling [1]. Characterization of left ventricular (LV) remodeling following an insult or major adverse cardiac event that disturbs this balance (eg: transmural myocardial infarction) can provide crucial information to guide non-transplant therapeutic options for improving cardiac function or surgical restoration of ventricular shape. In this study, analysis of endocardial morphology and function in remodeled LV territories is presented in the context of front-line quantitative 4D (3D + time) assessment of an antero-apical LV aneurysm in a 42 year old male patient from cine cardiac MRI data. In this regard, two promising shape analysis techniques are discussed: a) Hausdorff distance; and b) weighted spherical harmonics (SPHARM).

Звіти організацій з теми "Cardiac function analysis":

1

Yang, Yucheng, Chen Xue, Laozhui Zhang, Yanwei Wang, Meixiang Ouyang, Ju Li, Haipeng Wang, and Cuiyan Wang. Changes of Cardiac Function: Cardiac Adaptation in Patients with Hypothyroidism Assessed by Cardiac Magnetic Resonance-A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2024. http://dx.doi.org/10.37766/inplasy2024.4.0114.

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2

Liu, Gejing, Man Ren, Yingshi Du, Xinni Xu, Ruoyu Zhao, Yu Wu, Yongming Liu, and Liang Qi. A meta-analysis of Effect of thyroid hormone replacement therapy on the Cardiac diastolic function in Patients with Subclinical Hypothyroidism. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0083.

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Review question / Objective: P:Subclinical Hypothyroidism(Age over 18); I:thyroid hormone replacement therapy; C:baseline(before-after study in the same patient); O:Cardiac diastolic function measurement by echocardiography. Condition being studied: Subclinical hypothyroidism is associated with anomalies left ventricular diastolic functions, however, there are still disputes about whether to use levothyroxine for treatment. This meta-analysis aimed to determine whether levothyroxine (LT4), commonly used to treat hypothyroidism, affects cardiovascular indices in SCH patients as measured by echocardiography.
3

LI, Peng, Junhong Ren, and Yan Li. Lung ultrasound guided therapy for heart failure: an updated meta-analyses and trial sequential analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0124.

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Review question / Objective: We aim to evaluate the effect of lung ultrasound (LU) guided therapy on the rates of adverse cardiac events (MACE) in heart failure (HF) patients. Condition being studied: Previous studies have found that B-lines assessed by lung ultrasound can be used for risk stratification in patients with HF and to predict the occurrence of adverse cardiac events. Therefore, similar to BNP, lung ultrasound has clinical value in guiding the management of patients with HF. However, the role of LU in guiding HF therapy is still controversial. Moreover, previous study's samples are too small to explain the over clinical outcomes. Besides, previous meta-analyses study did not perform meta-regression and/or subgroup analyses, or further analyze other parameters, such as heart function, quality of life and length of hospital stay.
4

Li, Xiao, Fayang Ling, Wenchuan Qi, Sanmei Xu, Bingzun Yin, Zihan Yin, Qianhua Zheng, Xiang Li, and Fanrong Liang. Preclinical Evidence of Acupuncture on infarction size of Myocardial ischemia: A Systematic Review and Meta-Analysis of Animal Studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0044.

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Review question / Objective: Whether acupuncture is effective for infarction size on myocardial ischemia rat models. Condition being studied: Myocardial ischemia is a typical pathological condition of coronary heart disease (CHD), which has been a global issue with high incidence and mortality. Myocardial infarction caused by myocardial ischemia leads to cardiac dysfunction, and the size of myocardial infarction also determines the recovery and prognosis of cardiac function. Acupuncture, a long history of traditional Chinese medicine, is widely used to treat symptoms like thoracalgia and palpitation. Many researches based on rat experiments have shown that acupuncture affects infarction size, cardiac function, myocardial enzyme or arrhythmias severity on myocardial ischemia models; nevertheless, few literatures have systematically reviewed these studies, assessing the risk of bias, quality of evidence, validity of results, and summarizing potential mechanisms. A systematic review of animal studies can benefit future experimental designs, promote the conduct and report of basic researches and provide some guidance to translate the achievements of basic researches to clinical application in acupuncture for myocardial ischemia. Therefore, we will conduct this systematic review and meta analysis to evaluate effects of acupuncture on infarction size on myocardial ischemia rat models.
5

Fukuta, Hidekatsu, Toshihiko Goto, and Takeshi Kamiya. Association of epicardial fat with cardiac structure and function and cardiovascular outcomes: a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0109.

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6

HARBI, ALI, Kim Lam Soh, Putri Yubbu, Kim Geok Soh, and Salimah Japar. The Impact of Cardiac Rehabilitation on Psychosocial Factors, Functional Capacity, and Left Ventricular Function in PatientS with Coronary Artery Disease: Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2024. http://dx.doi.org/10.37766/inplasy2024.3.0128.

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7

Zheng, Xuehui, Xiangping Ma, Yan Qi, Chang Ma, Lingxin Liu, and Peili Bu. Effects of renal denervation on cardiac structure and function in heart failure with reduced ejection fraction:a: a systematic review and meta-analysis. International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2020. http://dx.doi.org/10.37766/inplasy2020.5.0009.

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8

Carney, Nancy, Tamara Cheney, Annette M. Totten, Rebecca Jungbauer, Matthew R. Neth, Chandler Weeks, Cynthia Davis-O'Reilly, et al. Prehospital Airway Management: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), June 2021. http://dx.doi.org/10.23970/ahrqepccer243.

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Objective. To assess the comparative benefits and harms across three airway management approaches (bag valve mask [BVM], supraglottic airway [SGA], and endotracheal intubation [ETI]) by emergency medical services in the prehospital setting, and how the benefits and harms differ based on patient characteristics, techniques, and devices. Data sources. We searched electronic citation databases (Ovid® MEDLINE®, CINAHL®, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and Scopus®) from 1990 to September 2020 and reference lists, and posted a Federal Register notice request for data. Review methods. Review methods followed Agency for Healthcare Research and Quality Evidence-based Practice Center Program methods guidance. Using pre-established criteria, studies were selected and dual reviewed, data were abstracted, and studies were evaluated for risk of bias. Meta-analyses using profile-likelihood random effects models were conducted when data were available from studies reporting on similar outcomes, with analyses stratified by study design, emergency type, and age. We qualitatively synthesized results when meta-analysis was not indicated. Strength of evidence (SOE) was assessed for primary outcomes (survival, neurological function, return of spontaneous circulation [ROSC], and successful advanced airway insertion [for SGA and ETI only]). Results. We included 99 studies (22 randomized controlled trials and 77 observational studies) involving 630,397 patients. Overall, we found few differences in primary outcomes when airway management approaches were compared. • For survival, there was moderate SOE for findings of no difference for BVM versus ETI in adult and mixed-age cardiac arrest patients. There was low SOE for no difference in these patients for BVM versus SGA and SGA versus ETI. There was low SOE for all three comparisons in pediatric cardiac arrest patients, and low SOE in adult trauma patients when BVM was compared with ETI. • For neurological function, there was moderate SOE for no difference for BVM compared with ETI in adults with cardiac arrest. There was low SOE for no difference in pediatric cardiac arrest for BVM versus ETI and SGA versus ETI. In adults with cardiac arrest, neurological function was better for BVM and ETI compared with SGA (both low SOE). • ROSC was applicable only in cardiac arrest. For adults, there was low SOE that ROSC was more frequent with SGA compared with ETI, and no difference for BVM versus SGA or BVM versus ETI. In pediatric patients there was low SOE of no difference for BVM versus ETI and SGA versus ETI. • For successful advanced airway insertion, low SOE supported better first-pass success with SGA in adult and pediatric cardiac arrest patients and adult patients in studies that mixed emergency types. Low SOE also supported no difference for first-pass success in adult medical patients. For overall success, there was moderate SOE of no difference for adults with cardiac arrest, medical, and mixed emergency types. • While harms were not always measured or reported, moderate SOE supported all available findings. There were no differences in harms for BVM versus SGA or ETI. When SGA was compared with ETI, there were no differences for aspiration, oral/airway trauma, and regurgitation; SGA was better for multiple insertion attempts; and ETI was better for inadequate ventilation. Conclusions. The most common findings, across emergency types and age groups, were of no differences in primary outcomes when prehospital airway management approaches were compared. As most of the included studies were observational, these findings may reflect study design and methodological limitations. Due to the dynamic nature of the prehospital environment, the results are susceptible to indication and survival biases as well as confounding; however, the current evidence does not favor more invasive airway approaches. No conclusion was supported by high SOE for any comparison and patient group. This supports the need for high-quality randomized controlled trials designed to account for the variability and dynamic nature of prehospital airway management to advance and inform clinical practice as well as emergency medical services education and policy, and to improve patient-centered outcomes.
9

Zhang, Yue, Pengna Re, Ailing Tang, Li Dong, Xiaoyi Hu, Hong Wang, and Fanglei Xu. Effect of exercise training for patients with atrial fibrillation after radiofrequency ablation on exercise endurance and cardiac function: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0122.

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Fukuta, Hidekatsu, Hiromi Hagiwara, and Takeshi Kamiya. Effects of angiotensin-receptor neprilysin inhibitor on exercise capacity, quality of life, and cardiac function in heart failure with preserved ejection fraction: a protocol for meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2021. http://dx.doi.org/10.37766/inplasy2021.7.0076.

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