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Статті в журналах з теми "C–X bond"
Xu, Da-Zhen, Ren-Ming Hu, and Yi-Huan Lai. "Iron-Catalyzed Aerobic Oxidative Cross-Dehydrogenative C(sp3)–H/X–H (X = C, N, S) Coupling Reactions." Synlett 31, no. 18 (July 21, 2020): 1753–59. http://dx.doi.org/10.1055/s-0040-1707195.
Повний текст джерелаRobertson, Katherine N., Osvald Knop, and T. Stanley Cameron. "C-H···H-C interactions in organoammonium tetraphenylborates: another look at dihydrogen bonds." Canadian Journal of Chemistry 81, no. 6 (June 1, 2003): 727–43. http://dx.doi.org/10.1139/v03-080.
Повний текст джерелаLiu, Dong, Chao Liu, and Aiwen Lei. "Carbon-Centered Radical Addition to C=X Bonds for C−X Bond Formation." Chemistry - An Asian Journal 10, no. 10 (June 23, 2015): 2040–54. http://dx.doi.org/10.1002/asia.201500326.
Повний текст джерелаValentini, Federica, Oriana Piermatti, and Luigi Vaccaro. "Metal and Metal Oxide Nanoparticles Catalyzed C–H Activation for C–O and C–X (X = Halogen, B, P, S, Se) Bond Formation." Catalysts 13, no. 1 (December 22, 2022): 16. http://dx.doi.org/10.3390/catal13010016.
Повний текст джерелаAllwohn, Jürgen, Ralf Hunold, Monika Pilz, Rolf-Günter Müller, Werner Massa, and Armin Berndt. "Nachweis starker C – Sn-Hyperkonjugation über Kristallstruktur und NMR-Daten eines C-Stannylmethylenborans / Evidence for Strong C–Sn-Hyperconjugation by Crystal Structure and NMR Data of a C-Stannylmethyleneborane." Zeitschrift für Naturforschung B 45, no. 3 (March 1, 1990): 290–98. http://dx.doi.org/10.1515/znb-1990-0304.
Повний текст джерелаNagorny, Pavel, and Zhankui Sun. "New approaches to organocatalysis based on C–H and C–X bonding for electrophilic substrate activation." Beilstein Journal of Organic Chemistry 12 (December 23, 2016): 2834–48. http://dx.doi.org/10.3762/bjoc.12.283.
Повний текст джерелаLiu, Dong, Chao Liu, and Aiwen Lei. "ChemInform Abstract: Carbon-Centered Radical Addition to C=X Bonds for C-X Bond Formation." ChemInform 46, no. 46 (October 27, 2015): no. http://dx.doi.org/10.1002/chin.201546253.
Повний текст джерелаLuo, Tian, Shanghui Tian, Jie-Ping Wan, and Yunyun Liu. "Recent Advances in Transition Metal-Free Halogenation of C(sp2)-H Bonds." Current Organic Chemistry 25, no. 10 (June 1, 2021): 1180–93. http://dx.doi.org/10.2174/1385272825666210122094423.
Повний текст джерелаHao, Wenyan, and Yunyun Liu. "C–H bond halogenation catalyzed or mediated by copper: an overview." Beilstein Journal of Organic Chemistry 11 (November 9, 2015): 2132–44. http://dx.doi.org/10.3762/bjoc.11.230.
Повний текст джерелаLiu, Nan-nan, and Yi-hong Ding. "A metal–metal bond passing through the arene ligand: a theoretical study on inverse sandwiches X[Sc–C8H8–Sc]nX (X = F, Cl, Br; n = 1, 2)." New Journal of Chemistry 39, no. 3 (2015): 1558–62. http://dx.doi.org/10.1039/c4nj01832j.
Повний текст джерелаДисертації з теми "C–X bond"
Taylor, Dawn. "Palladium-catalysed C-X bond formations." Thesis, University of Bath, 2006. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437449.
Повний текст джерелаVuong, Khuong Quoc Chemistry Faculty of Science UNSW. "Metal complex catalysed C-X (X = S, O and N) bond formation." Awarded by:University of New South Wales. Chemistry, 2006. http://handle.unsw.edu.au/1959.4/23015.
Повний текст джерелаMata, Campaña Yvette Angela. "Screening of Modular Carbohydrate Ligand Libraries in Asymmetric Metal-catalyzed C-C and C-X Bond Formation Reactions." Doctoral thesis, Universitat Rovira i Virgili, 2007. http://hdl.handle.net/10803/9090.
Повний текст джерелаAquesta tesi s'ha centrat en la síntesi de compostos derivats de la D-(+)-glucosa, de la D-(+)-fructosa i la D-(+)-galactosa i l'aplicació com a lligands de catalitzadors homogenis quirals en quatre reaccions asimètriques: substitució al·lílica, Heck, addició 1,2 i addició conjugada 1,4. Per assolir aquest objectiu, s'ha plantejat la síntesi de tres famílies de compostos: fosfit-oxazolina (L1-L5), fosfit-fosforoamidit (L6) i monofosfit (L7-L11) (Figura 1).
Després de la introducció (Capítol 1) i els objectius (Capítol 2), al capítol 3 es discuteix la síntesi i caracterització de les tres llibreries de compostos (L1-L11) i s'estudia l'aplicació de les tres llibreries a la reacció de substitució al·lílica asimètrica catalitzades per pal·ladi.
La primera llibreria de compostos fosfit-oxazolina (L1-L5) ha mostrat altes enantioselectivitats (fins a un 99%) i bones activitats en un ampli ventall de substrats amb diferents propietats electròniques i estèriques. S'han observat importants efectes al variar els substituents de l'anell oxazolina, de la quiralitat axial i dels diferents substituents del biaril. L'estudi de diferents intermedis de reacció pal·ladi al·lil mitjançant espectroscòpia de ressonància magnètica nuclear ha permès entendre el comportament catalític d'aquests compostos. L'estudi també ha indicat que l'atac nuclèofil té lloc preferentment al carboni al·lílic terminal localitzat trans al fosfit.
Figura 1. Fosfit-oxazolina (L1-L5), fosfit-fosforamidit (L6) i monofosfit (L7-L11).
Les reaccions de substitució asimètrica utilitzant els compostos fosfit-fosforoamidit (L6) han mostrat que l'excés enantiomèric depèn preferentment dels substituents de les posicions en para dels bifenils. Aquests efectes han estat diferents segons el tipus de substrat. S'han obtingut excessos enantiomèrics fins a un 89% i altes activitats utilitzant el substrat rac-1,3-difenil-acetoxipropè, rac-(E)-etil-2,5-dimetil-3-hex-4-enilcarbonat i el rac-3-acetoxicicloheptè. Pel substrat lineal 1-(1-naftil)al·lil acetat, aquests lligands han mostrat no ser útils en termes de regioselectivitat però s'han obtingut bons excessos enantiomèrics de fins a un 72%.
Si comparem aquests resultats amb els obtinguts amb els compostos fosfit-oxazolina (L1-L5) s'observa que el canvi de la funció oxazolina per la funció fosforoamidit té un efecte negatiu en la reacció de substitució al·lílica i en general decreixen les enantioselectivitats i la versalitat d'aquests compostos.
L'aplicació de la llibreria de compostos monofosfit (L7-L11) en la reacció de substitució al·lílica asimètrica ha mostrat moderades enantioselectivitats (fins a un 46%). Els resultats en la catàlisi es veuen afectats en gran mesura per la diferència en la mida de l'anell carbohidrat, de les configuracions del carboni-3 i del carboni-4 de l'esquelet del lligand i pel tipus de substituents de l'anell biaril.
El capítol 4 descriu l'aplicació dels compostos fosfit-oxazolina (L1-L5) com a lligands en la reacció de Heck asimètrica intermolecular. Una selecció correcta dels substituents en la funció oxazolina i del fosfit han permès obtenir excel·lents activitats (fins un 100% de conversió en 10 minuts), regioselectivitats i enantioselectivitats (fins un 99%) en un ampli rang de substrats utilitzant diferents fonts de triflat.
El capítol 5 descriu l'aplicació de les tres llibreries de compostos (L1-L11) a les reaccions d'addició 1,2 a aldehids catalitzades per níquel. En primer lloc, s'ha estudiat l'aplicació dels compostos L1-L6. S'ha observat que la selectivitat del procés depèn principalment del grup funcional unit a l'esquelet del lligand, de les propietats estèriques del substituent en la funció oxazolina i de l'estructura del substrat. S'ha obtingut fins a un 59% d'excés enantiomèric utilitzant el precursor de catalitzador que conté el lligand L3a. En canvi, la utilització de la llibreria de compostos monofosfit (L7-L11) ha mostrat elevades enantioselectivitats (fins a 94%) i activitats en diferents tipus de substrat utilitzant baixes concentracions de catalitzador i sense excés de lligand.
El capítol 6 descriu l'aplicació de les tres famílies de compostos (L1-L11) com a lligands en la reacció d'addició 1,4 catalitzada per coure de compostos organometàl·lics a diferents enones amb diferents propietats estèriques.
L'ús de les llibreries de compostos fosfit-oxazolina (L1-L5) i fosfit-fosforamidit (L6) han proporcionat bones enantioselectivitats (fins a 78%) en l'addició de reactius de trialquilalumini a diferents enones. En canvi, la llibreria de compostos monofosfit (L7-L11) ha mostrat bones activitats però enantioselectivitats fins a 57%.
The growing demand for enantiomerically pure compounds for the development of pharmaceuticals, agrochemicals and flavors has captured the interest of the chemist in the last few decades. Of the various methods for producing enantiopure compounds, enantioselective homogeneous metal catalysis is an attractive one. In this context, carbohydrates have many advantages: they are readily available, are highly functionalized and have several stereogenic centers. This enables series of chiral ligands to be synthesized and screened in the search for high activities and selectivities for each particular reaction.
In this context, this thesis focuses on the development of new chiral ligand libraries derived from carbohydrates, the synthesis of new catalyst precursors and their application in the Pd-catalyzed asymmetric allylic substitution, Pd-catalyzed asymmetric Heck reactions, Ni-catalyzed asymmetric addition of trialkylaluminium to aldehydes, and Cu-catalyzed asymmetric 1,4-conjugated addition of trialkylaluminium reagents to enones.
For this porpose, we have designed and syntezied 3 new sugar based ligand libraries: phosphite-oxazoline (L1-L5), phosphite-phosphoroamidite (L6) i monophosphite (L7-L11) (Figure 1).
After introduction (Chapter 1) and objectives (Chapter 2), in chapter 3 is discussed the synthesis and characterization of the ligand libraries (L1-L11) and and their application in the asymetric Pd-catalyzed allylic substituion reactions.
Using phosphite-oxazoline ligands (L1-L5) we observed important effects of the oxazoline substituents and the axial chirality and the substituents of the biaryl moieties. However, the effects of these parameters depended on each substrate. High enantioselectivities (up to 99%) and good activities have been achieved in a wide range of substrates with different steric and electronic properties.
The study of the Pd-1,3-diphenyl, 1,3-dimethyl and 1,3-cyclohexenyl allyl intermediates by NMR spectroscopy made it possible to understand the catalytic behaviour observed. This study also indicated that the nucleophilic attack takes place predominantly at the allylic terminal carbon atom located trans to the phosphite moiety.
Figura 1. Fosfit-oxazolina (L1-L5), fosfit-fosforamidit (L6) i monofosfit (L7-L11).
Asymmetric substitution reactions with catalyst precursors containing the phosphite-phosphoroamidite ligands showed that enantiomeric excesses depend strongly on the substituents at the para positions of the biphenyl moieties. However, these effects were different depending on the substrate in study. Enantiomeric excesses of up to 89% with high activities were obtained for rac-1,3-diphenyl-3-acetoxyprop-1-ene, rac-(E)-ethyl-2,5-dimethyl-3-hex-4-enylcarbonate and rac-3-acetoxycycloheptene. For the monosubstituted linear substrate 1-(1-naphthyl)allyl acetate, these ligands proved to be inadequate in terms of regioselectivities. However, we obtained good enantioselectivity by carefully selecting the substituents on the para position of the biphenyl moieties (ee's up to 72%).
If we compare these results with those from the catalyst precursors containing the previous phosphite-oxazoline ligands (L1-L5), we found that the replacement of the oxazoline moiety by a phosphoroamidite group decreased enantioselectivities and versatibility.
Asymmetric allylic alkylation with catalyst precursors containing the sugar-based monophosphite ligand library showed that the catalytic performance is highly affected by the size of the sugar backbone, the configurations at C-3 and C-4 of the ligand backbone and the type of substituents/configurations in the biaryl phosphite moiety. Low-to-moderate enantioselectivities (up to 46%) were obtained.
In the asymmetric Pd-catalyzed Heck reactions (Chapter 4) with catalysts precursors based on phosphite-oxazoline ligands, we obtained excellent activities (up to 100% conversion in 10 minutes), regio- (up to >99%) and enantioselectivities (up to 99%) were obtained in a wide range of substrates and triflate sources.
In the asymmetric Ni-catalyzed 1,2-addition of trialkylaluminium to aldehydes (Chpater 5) with catalysts precursors based on phosphite-oxazoline and phosphite-phosphoroamidite ligands, we found that the selectivity depends strongly on the type of functional group attached to the carbohydrate backbone, on the steric properties of the oxazoline substituents and on the substrate structure. Enantioselectivities up to 59% were obtained using the catalyst precursor containing the phosphite-oxazoline ligand L3a. In contrast to what we observed with the previous two ligand libraries, using sugar-based monophosphite ligands (L7-L11) provides high enantioselectivities (up to 94% ee) and activities in different substrate types, with low catalysts loadings and without excess of ligand.
In Chapter 6, we described the phosphite-oxazoline and phosphite-phosphoroamidite ligands as chiral auxiliaries in the asymmetric Cu-catalyzed 1,4-conjugated addition of trialkylaluminium reagents to several enones provides good enantioselectivities (up to 80% ee).
In the asymmetric Cu-catalyzed asymmetric 1,4-conjugated addition of trialkylaluminium reagents to several enones with catalysts precursors based on sugar monophosphite ligands, we found good activites and enantioselectivities up to 57% ee.
Borràs, Noguera Carlota. "Sustainable and cost-effective development of chiral metal-catalysts for C-H and C-X bond forming reactions." Doctoral thesis, Universitat Rovira i Virgili, 2018. http://hdl.handle.net/10803/664741.
Повний текст джерелаLa obtención de compuestos enantioméricamente puros se ha convertido una necesidad que ha conducido a un importante progreso en la catálisis asimétrica, principalmente usando compuestos organometalicos quirales. Entre las diferentes estrategias en la optimización de los catalizadores para conseguir elevadas selectividades y actividades, el diseño y la correcta selección de ligandos quirales, modificando sus propiedades es fundamental y la más utilizada. Que un ligando sea fácil de sintetizar a partir de compuestos de partida accesibles y que estos ligandos sean estables y fáciles de manipular, tienen un elevado interés en la industria. En este contexto, el principal objetivo de esta tesis es la síntesis de distintas familias de ligandos quirales, cumpliendo con los requisitos previamente mencionados, y su posterior aplicación en distintas reacciones asimétricas de alto interés industrial: hidrogenación de alquenos funcionalizados y no funcionalizados catalizados por Rh y Ir, hidrogenación de cetonas catalizada por Ir, reacciones de substitución alílica catalizada por Pd y reacciones de substitución propargílica catalizada por Cu. Se han sintetizado diferentes familias de ligandos Fosfito/fosfinito-tioéter/selenoéter, carbeno-tioéter, amino-fosfito/fosfinito/fosfina, y varias familias de ligandos tridentados.
The obtaining of enantiomerically pure compounds has become a need that led to an important progress in asymmetric catalysis, mainly using organometallic chiral compounds. Among different strategies to optimize catalysts in order to obtain high selectivities and activities, the design and the correct selection of chiral ligands, modifying their properties, is fundamental and the most used strategy. Ligands easy to synthesize from readily accessible starting material and stable and easy to manipulate ligands, have a high interest in the industry. In this context, the main objective of this thesis is the synthesis of different chiral ligand families, according to the previously mentioned requirements, and their application in different asymmetric reactions with high industrial interest: Rh- and Ir-catalyzed hydrogenation of functionalized and minimally functionalized olefins; Ir-catalyzed hydrogenation of simple ketones; Pd-catalyzed asymmetric substitution of allylic acetates and Cu-catalyzed propargylic substitution. There have been synthesized different phosphite/phosphinite-thioether/selenoether, carbene-thioether, amino-phosphite/phosphinite/phosphine and various tridentated ligand families.
Mazuela, Aragón Javier. "Design and screening of biaryl phosphite-based ligand libraries for asymmetric reduction and c-c and c-x bond forming reactions." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/96665.
Повний текст джерелаDuring the last years, phosphite-containing compounds have proved to be efficient ligands for several metal-catalyzed transformations. In this context, we have developed several phosphite-containing ligand libraries for their application in reactions leading to enantiomerically pure products. More concretely we have studied: (a) the synthesis and screening of 9 phosphite-nitrogen ligand libraries in the Ir-catalyzed hydrogenation of minimally functionalized olefins, Pd-catalyzed allylic substitution and Heck reactions. These ligand libraries have been designed by systematic modification of several ligand parameters. In all cases excellent activities, regio- and enantioselectivities (ee’s up to >99%) have been obtained for a broad range of substrates. These results compete favorably with those reported previously in the literature. (b) the screening of several types of phosphite containing ligand libraries in the Rh-catalyzed hydroformylation of vinylarenes, heterocyclic olefins and 1,1’-terminal enol esters obtaining promising results (ee’s up to 76%).
Esswein, Arthur J. "Late transition metal bimetallics for photocatalytic hydrogen production, M-X and C-H bond activation." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/40970.
Повний текст джерелаVita.
Includes bibliographical references.
Broadly defined this thesis has focused on the design and study of molecular catalysts that engender multi-electron reactions and photoreactions on small molecule substrates relevant to solar energy conversion. Specifically the molecular design elements employed have focused on bimetallic complexes of late transition metals that exhibit an unusual two-electron mixed valence ground state. Initial studies focused on the mechanistic elucidation of the reported photocatalytic production of hydrogen from homogeneous hydrohalic acid solution using a two-electron mixed valence dirhodium complex. Studies aimed at understanding and improving the photochemical quantum efficiency for challenging M-X (X = CI, Br-) bond photoactivations were undertaken by incorporating gold into a heterobimetallic rhodium-gold construct. Additionally the organometallic reactivity of two-electron mixed valence diiridium cores was explored with a specific emphasis on C-H bond activations in order to extend the cooperative bimetallic reactivity observed in the dirhodium systems beyond HX and H2 substrates to alkanes and arenes.
by Arthur J. Esswein.
Ph.D.
Margalef, Pallarès Jèssica. "Screening of modular and readily available ligand libraries for C-X (X=H, C, N and O) bond forming reactions. The use of DFT studies for catalysts optimization." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/386578.
Повний текст джерелаEl creciente interés para la obtención de compuestos enantioméricamente puros para la obtención de compuestos enantioméricamente puros, ha conducido a un importante desarrollo de la catálisis asimétrica. En este contexto, esta tesis se centra en la síntesis de varias familias de ligandos quirales altamente modulares a partir de compuestos de fácil disponibilidad. Concretamente, se ha trabajado en la síntesis de ligandos fosfito-tioéter, fosfito-piridina, fosfito-triazoles y ligandos hidroaximida y tioamida. Todos ellos tienen en común que son sólidos, estables y por lo tanto de fácil manipulación. Estos ligandos se han aplicado en la hidrogenación de olefinas funcionalizadas y no funcionalizadas catalizada por Rh e Ir, en la reducción de cetonas mediante transferencia de hidrógeno catalizada por Rh y Ru, en reacciones de sustitución alílica catalizada por Pd y en el adición de organoaluminiatos a aldehídos catalizada por Ni. Además, en algunos casos se han realizado estudios DFT para agilizar el proceso de optimización de los ligandos. Así pues, se ha logrado la obtención de diferentes compuestos químicos quirales de alto interés sintético (ej. alcoholes, alcanos funcionalizados y no funcionalizados, alilos sustituidos) en grandes enantioselectividades y en el mejor de los casos se han conseguido los productos en su forma enantioméricamente pura (> 99% ee).
The growing interest in obtaining enantiomerically pure compounds in obtaining enantiomerically pure compounds has led to a significant development in the field of asymmetric catalysis. In this context, this thesis is focused on the synthesis of several families of highly modular chiral ligands from readily available compounds. Specifically, we worked on the synthesis of thioether-phosphite ligands, phosphite-pyridine, phosphite-triazole and hidroaximide and thioamide ligands. They all have in common that are solid, stable and therefore easy to handle. These ligands have been applied in the Rh- and Ir-catalyzed hydrogenation of functionalized and unfunctionalized olefins, in the Ru- and Rh-catalyzed asymmetric transfer hydrogenation of ketones, in Pd-catalyzed allylic substitution reactions and in the Ni-catalyzed addition of organoalumininum to aldehydes. Moreover, in some cases DFT studies have been performed to speed up the optimization of ligands. Hence, a variety of chiral chemical compounds of high synthetic interest (i. e. alcohols, functionalized and non-functionalized alkanes, substituted allyl) lhigh enantioselectivities were achieved and in some cases the products were obtained in their enantiomerically pure form(> 99% ee).
Mazloomi, Zahra. "New approaches to perfluoroalkylation of aromatic compounds, and tailor-made catalysts for C-X bond forming and water oxidation reactions. Mechanistic insights." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/450517.
Повний текст джерелаEsta tesis está dividida en dos partes: la primera parte se realizó en el Instituto Catalán de Investigación Química (ICIQ) desde 2012 hasta 2015, esta parte trata sobre la perfluoroalquilación de sustratos aromáticos e incluye dos proyectos principales. El objetivo del primer proyecto era la producción en flujo continuo de CuCF3 como reactivo trifluorometilado y la confirmación de su eficacia en la trifluorometilación de algunos haluros aromáticos, los cuales fueron tratados con CuCF3 y se convirtieron selectivamente en compuestos trifluorometilados. En el segundo proyecto, el objetivo era transformar varios haluros vinílicos a análogos trifluorometilados y pentafluoroetilados usando los reactivos nucleófilos CuCF3 y CuC2F5, los cuales habían sido utilizados previamente en el mismo grupo. La segunda parte se ha llevado a cabo en la Universidad de Rovira i Virgili (URV) a partir de 2015 hasta 2017. Esta parte trata sobre diferentes reacciones catalíticas de formación de enlaces C-X y estudios mecanísticos sobre de estas. Esta parte contiene 4 proyectos de investigación. Tres de ellos tratan sobre la síntesis y aplicación en varias reacciones catalíticas de gran relevancia de varios complejos de carbeno anormales con Ir (I), Ir (III) y Ru (II). Estos catalizadores altamente eficaces se aplicaron con éxito en la hidrogenación por transferencia de enlaces C = O, C = N y C = C, también en la deshidrogenación de alcoholes y la oxidación con agua. El último proyecto trata sobre la formación catalítica asimétrica de enlaces C-C con una nueva y versátil biblioteca de ligandos P-N quirales. Todos los objetivos de la segunda parte de la tesis se realizaron con éxito. En resumen, en esta tesis se han realizado diversas transformaciones químicas importantes, todas ellas de gran interés en la formación de productos farmacéuticos, agroquímicos, naturales, de química fina y en la producción de energía limpia. El trabajo hecho en esta tesis contiene aspectos fundamentales de la química y desde el punto de vista químico e industrial existe una gran demanda en el desarrollo y mejora de los procesos mencionados.
This dissertation divided into two main parts: the first part which had been done from 2012 until 2015 in Institute of chemical research of Catalonia (ICIQ) is about perfluoroalkylation of aromatic substrate including two main works. In the first project the goal was continuous flow production of CuCF3 as a trifluoromethylated reagent and confirming its efficiency in trifluoromethylation of some aromatic halides which were treated with batch made CuCF3 reagent and selectively converted to trifluoromethylated conterparts. In the second project the target was transforming several vinylic halides to trifluoromethylated and pentafluoroethylated analoges with nucleophilic CuCF3 and CuC2F5 reagents which were demonstrated previously in the same group. The later part has been carried out in the University of Rovira I Virgili (URV) from 2015 until 2017. Generally this part is about different catalytic C-X bond forming reactions with mechanistic insights which contains 4 research projects. Three of them are about synthesis and catalytic application of several Ir(I), Ir(III) and Ru(II) abnormal carbene complexes in several important and challenging catalytic reactions. These highly efficient catalysts successfully applied in transfer hydrogenation of C=O, C=N and C=C functionalities, alcohol dehydrogenation and water oxidation. The last project is asymmetric catalytic formation of C-C bond with a new and versatile chiral P-N ligand library. All of the objectives for the second part of thesis were performed successfully. In conclusion, various important chemical transformation were made in this thesis which all of them are vital in pharmaceuticals, agrochemicals, fine and natural products and the production of clean energy. The total works in this thesis are so important in chemistry and there is a huge demand about developing and improving the mentioned processes from the chemical and industrial point of view.
Smith, Daniel L. "Selective incorporation of the C-F bond as a conformational tool in quadruplex DNA ligand design." Thesis, University of St Andrews, 2012. http://hdl.handle.net/10023/3169.
Повний текст джерелаBiosca, Brull Maria. "Fitting the catalysts for effective enantioselective C-X bond forming reactions. Theoretically guided ligand design and mechanistic investigations." Doctoral thesis, Universitat Rovira i Virgili, 2018. http://hdl.handle.net/10803/665121.
Повний текст джерелаLa creciente demanda de compuestos enantioméricamente puros, ha incrementado el interés por el desarrollo de metodologías para la obtención de dichos compuestos. Entre ellas, la catálisis asimétrica es la técnica mas utilizada. En dicha metodología, la elección del ligando quiral es clave para la obtención de elevada actividades i enantioselectividades. En este contexto, esta tesis se centra en la síntesis de diferentes familias de ligandos quirales altamente modulares a partir de productos de partida de elevada disponibilidad. Más concretamente, se ha trabajado en la síntesis de ligandos heterodadores P-oxazoline (P= fosfina, fosfinito, fosfito, fosforamidito), P-otros grupos N-dadores (P= fosfito, fosforamidito, fosfonito y N= tiazol, sulfoximina, hidrazona, amina, piridina), P-tioéter (P= fosfina, fosfinito, fosfito) i una familia de ligandos fosfina quiral-fosfito. Estos ligandos se han aplicado en la reacción de hidrogenación de olefinas funcionalitzadas i mínimamente funcionalitzadas catalizada por Rh i Ir, la reacción de substitución alílica y la reacción de protonación descarboxilativa de oxindolas ambas catalizadas por Pd. Además, en algunos casos, se han realizado cálculos computacionales en combinación con ensayos experimentales para estudiar el origen de las enantioselectividades obtenidas o bien para guiar la optimización de los ligandos.
The growing demand on enantiomerically pure compounds has stimulated the interest for the development of methodologies to obtain these compounds. Among them, asymmetric catalysis is one of the most employed tools. In this technic, the choice of the chiral ligand is fundamental to obtain high levels of activity and enantioselectivity. In this context, this thesis is focused on the synthesis of several families of highly modular chiral ligands from readily available starting materials. Particularly, we worked on the synthesis of P-oxazoline (P= phosphine, phosphinite, phosphite, phosphoroamidite), P-other N-donor groups (P= phosphite, phosphoroamidite, phosphonite and N= thiazole, sulfoximine, hydrazone, amine, pyridine), P-thioether (P= phosphine, phosphinite, phosphite) and a family of P*-stereogenic phosphine-phosphite ligands. These ligands have been applied in the Rh- and Ir-catalyzed hydrogenation of functionalized and minimally functionalized olefins, Pd-catalyzed allylic substitution reaction and Pd-catalyzed decarboxylative protonation. Furthermore, in some cases, DFT studies in combination with experimental ones have been performed to better understand the origin of the obtained enantioselectivities or in order to guide the ligand optimization.
Книги з теми "C–X bond"
Vigalok, Arkadi, ed. C-X Bond Formation. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2.
Повний текст джерелаC-X bond formation. Heidelberg: Springer, 2010.
Знайти повний текст джерелаRibas, Xavi, ed. C-H and C-X Bond Functionalization. Cambridge: Royal Society of Chemistry, 2013. http://dx.doi.org/10.1039/9781849737166.
Повний текст джерелаVigalok, Arkadi. C-X Bond Formation. Springer, 2012.
Знайти повний текст джерелаMa, Dawei, Ian J. S. Fairlamb, Guosheng Liu, Xavi Ribas, and Livi Mirica. C-H and C-X Bond Functionalization: Transition Metal Mediation. Royal Society of Chemistry, The, 2013.
Знайти повний текст джерелаAndersson, Pher G. Innovative Catalysis in Organic Synthesis: Oxidation, Hydrogenation, and C-X Bond Forming Reactions. Wiley & Sons, Incorporated, John, 2012.
Знайти повний текст джерелаAndersson, Pher G. Innovative Catalysis in Organic Synthesis: Oxidation, Hydrogenation, and C-X Bond Forming Reactions. Wiley & Sons, Limited, John, 2012.
Знайти повний текст джерелаAndersson, Pher G. Innovative Catalysis in Organic Synthesis: Oxidation, Hydrogenation, and C-X Bond Forming Reactions. Wiley & Sons, Incorporated, John, 2012.
Знайти повний текст джерелаAndersson, Pher G. Innovative Catalysis in Organic Synthesis: Oxidation, Hydrogenation, and C-X Bond Forming Reactions. Wiley & Sons, Incorporated, John, 2012.
Знайти повний текст джерелаTrost, Barry M. Additions to C-X ?-Bonds. Elsevier Science & Technology Books, 1992.
Знайти повний текст джерелаЧастини книг з теми "C–X bond"
Eisen, Moris S. "Catalytic C–N, C–O, and C–S Bond Formation Promoted by Organoactinide Complexes." In C-X Bond Formation, 157–84. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_7.
Повний текст джерелаMuñiz, Kilian. "Transition Metal Catalyzed Electrophilic Halogenation of C–H Bonds in Alpha-Position to Carbonyl Groups." In C-X Bond Formation, 1–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_1.
Повний текст джерелаVigalok, Arkadi, and Ariela W. Kaspi. "Late Transition Metal-Mediated Formation of Carbon–Halogen Bonds." In C-X Bond Formation, 19–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_2.
Повний текст джерелаBichler, Paul, and Jennifer A. Love. "Organometallic Approaches to Carbon–Sulfur Bond Formation." In C-X Bond Formation, 39–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_3.
Повний текст джерелаGlueck, David S. "Recent Advances in Metal-Catalyzed C–P Bond Formation." In C-X Bond Formation, 65–100. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_4.
Повний текст джерелаVedernikov, Andrei N. "C–O Reductive Elimination from High Valent Pt and Pd Centers." In C-X Bond Formation, 101–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_5.
Повний текст джерелаHintermann, Lukas. "Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes." In C-X Bond Formation, 123–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12073-2_6.
Повний текст джерелаMani, Devendra, and E. Arunan. "The X-C…Y Carbon Bond." In Challenges and Advances in Computational Chemistry and Physics, 323–56. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14163-3_11.
Повний текст джерелаOhno, Hiroaki. "Intramolecular CX Bond Formation between CX or XH and Alkynes." In Transition-Metal-Mediated Aromatic Ring Construction, 485–536. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118629871.ch19.
Повний текст джерелаDeuss, Peter J., Megan V. Doble, Amanda G. Jarvis, and Paul C. J. Kamer. "Hybrid Catalysts for Other CC and CX Bond Formation Reactions." In Artificial Metalloenzymes and MetalloDNAzymes in Catalysis, 285–319. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527804085.ch10.
Повний текст джерелаТези доповідей конференцій з теми "C–X bond"
Nakrachi, Aziz, and Genevieve Dauphin-Tanguy. "A Distributed Parameter Pseudo Bond Graph for Heat Conduction Modelling: Notion of Cellular Bond Graph." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-41751.
Повний текст джерелаSubramanian, Raghavendran, and Kazem Kazerounian. "Improved Molecular Model of a Peptide Unit for Proteins." In ASME 2006 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/detc2006-99315.
Повний текст джерелаJay, Raphael M., Ambar Banerjee, Torsten Leitner, Robert Stefanuik, Ru-Pan Wang, Jessica Harich, Emma Beale, et al. "From Femtosecond Excited-State and Dissociation Dynamics to Nanosecond Reaction Kinetics: Following C-H Bond Activation with X-rays." In International Conference on Ultrafast Phenomena. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/up.2022.tu1a.2.
Повний текст джерелаMusalek, Radek, Jan Medricky, Zdenek Pala, Ondrej Kovarik, Libor Tomek, Nicholas Curry, and Stefan Bjorklund. "Fatigue Performance of TBCs on Hastelloy X Substrate during Cyclic Bending." In ITSC2015, edited by A. Agarwal, G. Bolelli, A. Concustell, Y. C. Lau, A. McDonald, F. L. Toma, E. Turunen, and C. A. Widener. ASM International, 2015. http://dx.doi.org/10.31399/asm.cp.itsc2015p0406.
Повний текст джерелаYuan, K., K. P. Jonnalagadda, Y. Yu, R. L. Peng, X. H. Li, X. Ji, and J. Shen. "Thermal Fatigue Failure of Thermal Barrier Coatings with a High-Cr MCrAlY Bond Coat." In ITSC 2016, edited by A. Agarwal, G. Bolelli, A. Concustell, Y. C. Lau, A. McDonald, F. L. Toma, E. Turunen, and C. A. Widener. DVS Media GmbH, 2016. http://dx.doi.org/10.31399/asm.cp.itsc2016p0273.
Повний текст джерелаTiwari, Santosh K., and Brian K. Paul. "Application of Nickel Nanoparticles in Diffusion Bonding of Stainless Steel Surfaces." In ASME 2008 International Manufacturing Science and Engineering Conference collocated with the 3rd JSME/ASME International Conference on Materials and Processing. ASMEDC, 2008. http://dx.doi.org/10.1115/msec_icmp2008-72151.
Повний текст джерелаZhang, Q., C. J. Li, C. X. Li, G. J. Yang, X. R. Wang, H. T. Wang, and S. C. Lui. "Preliminary Study of Oxidation Behavior of Cold Sprayed Nanostructured NiCrAlY Bond Coatings." In ITSC2007, edited by B. R. Marple, M. M. Hyland, Y. C. Lau, C. J. Li, R. S. Lima, and G. Montavon. ASM International, 2007. http://dx.doi.org/10.31399/asm.cp.itsc2007p0457.
Повний текст джерелаFernández, J., M. Gaona, and J. M. Guilemany. "The Influence of Thermal Treatment on Hydroxyapatite Coatings Obtained by HVOF." In ITSC2006, edited by B. R. Marple, M. M. Hyland, Y. C. Lau, R. S. Lima, and J. Voyer. ASM International, 2006. http://dx.doi.org/10.31399/asm.cp.itsc2006p0011.
Повний текст джерелаSuzuki, Koji, Yoshihiro Deyashiki, Junji Nishioka, Kazunori Toma, and Shuji Yamamoto. "THE INHIBITOR OF ACTIVATED PROTEIN C: STRUCTURE AND FUNCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642963.
Повний текст джерелаKaraoglanli, A. C., A. Turk, Ð. Ozdemir, and F. Ustel. "Oxidation Behavior of Thermal Barrier Coatings With Cold Gas Dynamic Sprayed CoNiCrAlY Bond Coats." In 13th International Conference on Plasma Surface Engineering September 10 - 14, 2012, in Garmisch-Partenkirchen, Germany. Linköping University Electronic Press, 2013. http://dx.doi.org/10.3384/wcc2.420-423.
Повний текст джерелаЗвіти організацій з теми "C–X bond"
McFarland, Eric, Horia Metiu, and Michael Gordon. Fundamental Mechanisms of C-X bond Transformations on Complex Molten Surfaces. Office of Scientific and Technical Information (OSTI), July 2019. http://dx.doi.org/10.2172/1580080.
Повний текст джерелаLitaor, Iggy, James Ippolito, Iris Zohar, and Michael Massey. Phosphorus capture recycling and utilization for sustainable agriculture using Al/organic composite water treatment residuals. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600037.bard.
Повний текст джерелаRafaeli, Ada, Russell Jurenka, and Chris Sander. Molecular characterisation of PBAN-receptors: a basis for the development and screening of antagonists against Pheromone biosynthesis in moth pest species. United States Department of Agriculture, January 2008. http://dx.doi.org/10.32747/2008.7695862.bard.
Повний текст джерелаShomer, Ilan, Ruth E. Stark, Victor Gaba, and James D. Batteas. Understanding the hardening syndrome of potato (Solanum tuberosum L.) tuber tissue to eliminate textural defects in fresh and fresh-peeled/cut products. United States Department of Agriculture, November 2002. http://dx.doi.org/10.32747/2002.7587238.bard.
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