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Feoktistova, N. A., M. A. Shtarberg, E. V. Egorshina, G. K. Doroshenko, L. Ya Etmanova, and L. G. Tertychnaya. "VEGETABLE PROTEIN DECREASES BLOOD CHOLESTEROL." Amur Medical Journal, no. 4 (2017): 31–32. http://dx.doi.org/10.22448/amj.2017.3.31-32.
DR. USMAN M.S, DR USMAN M. S., and DR B. A. THOBANI DR. B.A.THOBANI. "Correlation of Fitness, Fatness, Blood Cholesterol and Blood Sugar." International Journal of Scientific Research 2, no. 9 (June 1, 2012): 383–85. http://dx.doi.org/10.15373/22778179/sep2013/134.
POLZIEN, GLADYS. "Blood Cholesterol Levels." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 25, no. 2 (February 2007): 136–39. http://dx.doi.org/10.1097/00004045-200702000-00016.
Craig, Steven R., Rupal V. Amin, Daniel W. Russell, and Norman F. Paradise. "Blood cholesterol screening." Journal of General Internal Medicine 15, no. 6 (June 2000): 395–99. http://dx.doi.org/10.1046/j.1525-1497.2000.03509.x.
Siscovick, David S. "Lowering blood cholesterol." Journal of General Internal Medicine 1, no. 3 (May 1986): 196–97. http://dx.doi.org/10.1007/bf02602337.
Hussain, Shabbir, Safdar Amir, and Naureen Naeem. "Nature and Effects of Cholesterol; Its Origin, Metabolism and Characterization." Lahore Garrison University Journal of Life Sciences 3, no. 4 (April 22, 2020): 196–203. http://dx.doi.org/10.54692/lgujls.2019.030465.
Cholesterol ((3β)-cholest-5-en-3-ol) is basically a fatty component present in blood, plasma and tissues. It belongs to the class of lipids namely steroids and is formed from squalene via lanosterol. It is present as a combination of cholesterol and cholesteryl esters in almost all types of foodstuffs. There is the direct relation between the risk of cardiovascular sicknesses and the total cholesterol amount in human blood. The bad- and good-cholesterol are types of lipoproteins. Good-cholesterol basically eliminates cholesterol from bloodstream while bad-cholesterol releases cholesterol into the blood and various part of body. Cholesterol amount can be reduced by physical activity or by use of proper diet. Cholesterol can be characterized by the SIM-selected ion monitoring, HPLC, UHPLC, GLC, GC-MS, LC-MS.
Macklin, Diana C. "A comparison of cholesterol measurements via various blood sample types." Virtual Press, 1991. http://liblink.bsu.edu/uhtbin/catkey/774768.
There has been inconsistencies in the performance of dry-chemistry analyzers using different blood sample types. Therefore, the purpose of this study was to determine precision and accuracy of both capillary and venous whole blood analyzed by the Reflotron (Boehringer Mannheim Diagnostics, Indianapolis, Indiana) and capillary plasma analyzed by the Ektachem DT60 (Eastman Kodak Company, Rochester, New York). Fifty subjects were recruited to provide a representative sample of cholesterol concentrations. One technician performed two fingerstick punctures and one venipuncture on each subject and analyzed the blood sample types in duplicate using each of the dry-chemistry analyzers. The methods and sample types utilized for comparison of total cholesterol are summarized below.ReflotronEktachem DT60Sigma2-Fingerstick whole2-Fingerstick plasma2-Venipuncture plasmablood2-Venipuncture whole2-Venipuncture plasmablood2-Veni uncture lasmaThe mean percent variation of the duplicate samples analyzed revealed all sample types, with the exception of fingerstick whole blood analyzed by theReflotron, met the LSP ideal goal for precision of 5 3% CV. Fingerstick wholeblood CV was 3.1%, meeting the current LSP standard of _5 5% CV for precision. The Sigma wet-chemistry assay for determination of total cholesterol was used as the reference for assessment of bias of each of the sample types. Fingerstick whole blood, via the Reflotron method, produced a positive 5.5% bias when compared to the reference, failing to meet the current LSP goal for acceptable accuracy (±5% bias). Venous whole blood analyzed using the Reflotron met this goal with a bias of +3.3%. Fingerstick plasma, via the Ektachem DT60 method, produced a bias of +2.1%, meeting the ideal LSP goal of ±3% bias. Venous plasma as measured by both the Reflotron and Ektachem DT60 also met this ideal goal (+2.0% and +1.8% bias, respectively). Overall, precision and accuracy of all sample types, with the exception of fingerstick whole blood, when analyzed by their respective dry-chemistry analyzer was acceptable. School of Physical Education
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Vela-Melton, Dorothy Louise. "Self-esteem and blood pressure, cholesterol, thyroxine and leukocytes." CSUSB ScholarWorks, 1991. https://scholarworks.lib.csusb.edu/etd-project/460.
Lewington, Sarah. "Blood pressure, cholesterol and premature death : towards the real relationships." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:517a1b6c-4752-46e7-868b-48a4ea078e69.
This thesis is based on a worldwide overview (meta-analysis) of prospective observational studies of blood pressure and cholesterol, involving a centralised collection of data on over one million individuals from 59 studies, which I have co- ordinated since its inception. Analytically, the aim has been to develop and to use appropriate statistical techniques to assess the age- and sex-specific associations of usual blood pressure and of usual cholesterol with cause-specific mortality. Since the data set is uniquely large, and because appropriate methods of analysis (with full account taken of the time-dependent nature of the regression dilution bias) have been developed and used, these associations have been established more reliably. An integral part of the methodological element of the thesis has been to investigate the systematic underestimation of associations between risk factor and disease that are obtained when only a single baseline measurement is used to assess levels of such risk factors (the regression dilution bias). The extent of this bias has been investigated in each study that had repeat measurements of risk factors during follow-up. One particularly novel aspect has been the emphasis on, and methods developed to account for, the regression dilution bias in several studies simultaneously and in an appropriately time-dependent way. This thesis illustrates the extent to which random error and inappropriate statistical analysis lead to misleading conclusions concerning the importance of blood pressure and blood cholesterol, particularly in premature death. Only by studying adequate numbers of deaths (136,000 deaths among 1 million adults during 13 million person- years of follow-up) and by using appropriate statistical techniques - taking proper account of (a) the regression dilution bias; (b) the full range of blood pressure and cholesterol; (c) the opposing effects of HDL.and the remaining non-HDL cholesterol; and (d) age at death - did it become possible to provide reliable results on the true relationships between blood pressure, cholesterol fractions and vascular and other causes of death. These analyses have demonstrated reliably that, as causes of IHD death in early middle age, blood pressure and blood lipids are three to five times more important than suggested by inappropriate analyses, with no clinically relevant inverse associations with cancer or other non-vascular mortality (except, surprisingly, COPD).
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Govender, Gwensweri, University of Western Sydney, and College of Science Technology and Environment. "Fabrication and characterisation of eletrochemical biosensors for the determination of cholesterol." THESIS_CSTE_XXX_Govender_G.xml, 2001. http://handle.uws.edu.au:8081/1959.7/461.
During the course of this study, an extensive investigation was conducted into the measurement of free and total cholesterol by fabrication of cholesterol biosensors. Specific areas investigated in-depth included the immobilisation of enzymes into conducting polypyrrole (PPy) film, bovine serum albumin-glutaraldehyde (BSA-GLA) gel and a hybrid bi-layer of PPy and BSA-GLA. Key parameters for the reliable measurement of cholesterol were optimised. The optimum parameters Doctor of Philosophy (PhD)
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Huang, Tingyu Tina, and 黄亭语. "Systematic review: effect of tartary buckwheat in controlling blood cholesterol." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46937298.
Wilson, Stephanie Helen. "Pathogenesis and treatment of cholesterol-related early vascular injury." Thesis, The University of Sydney, 2000. https://hdl.handle.net/2123/28453.
This thesis describes studies into the pathogenesis of Cholesterol—related early
vascular injury. In addition, this thesis examines the potential reversibility of
this injury with 2 agents: a) simvastatin, an HMGCoA reductase inhibitor, in a
model independent of any reduction in lipids and 2) high dose aspirin.
Hypercholesterolaemia led to a decrease in NO bioavailability, in association
with a decrease in the enzyme, endothelial nitric oxide synthase and increased
oxidative stress. In addition, there was an increase in the pro—inflammatory
transcription factor, NF—KB, in the intima of the epicardial coronary arteries.
Moreover, activated NF—KB was present in macrophages, foam cells and
vascular smooth muscle cells in coronary atheromatous plaque and its
expression increased in unstable coronary syndromes. These data support a
role for NF—KB in the pathogenesis of early atherosclerosis and the
development of unstable coronary syndromes.
In addition, this thesis demonstrated for the first time that simvastatin, an
HMGCoA reductase inhibitor, preserves endothelium—dependent
vasorelaxation in both large and small coronary vessels in porcine
experimental HC, despite no reduction in plasma lipids. This effect was
associated with normalisation of eNOS protein levels. Furthermore, in vivo
plasma markers of oxidative stress were attenuated by treatment with
simvastatin. However, there was no attenuation in the activation of the
proinflammatory transcription factor, NF—KB. These studies suggest a role for
the HMGCoA reductase inhibitors in reducing cardiac morbidity and
mortality, beyond their effect on cholesterol levels.
The current studies also demonstrated that high dose aspirin therapy preserved
endothelial function in large coronary vessels. This alteration in the
generation of prostanoids in favour of vasodilatation may be an important
component of the therapeutic benefit of aspirin in HC-induced atherosclerosis.
In summary, results of studies described in this thesis provide insights into the
molecular mechanisms that may be responsible for early vascular injury in
hypercholesterolaemia and its reversibility with the therapeutic agents, simvastatin
and high dose aspirin.
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Neubauer, Tamara E. "Cholesterol reduction in men : an experimental investigation of intensive treatment with frequent feedback versus a simple educational treatment /." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-03122009-040807/.
Lee, Sun Min. "Studies of the Mechanism of Plasma Cholesterol Esterification in Aged Rats." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc331051/.
The study was performed to determine factors influencing the esteriflcation of plasma cholesterol in young and aged rats. The distribution of LCAT activity was determined following gel nitration chromatography and ultracentrifugation of whole plasma respectively. When rat plasma was fractionated on a Bio-Gel A-5 Mcolumn, LCAT activity was found to be associated with the HDL fraction. A similar result was observed upon 24 hr density gradient ultracentrifugation of the plasma. However, following prolonged 40 hr preparative ultracentrifugation, the majority of the LCAT activity was displaced into the lipoprotein-free infranatant fraction (d> 1.225 g/ml). The dissociation of LCAT from the HDL fraction occured to a smaller extent in aged rat plasma than in young rat plasma. Plasma incubation (37°C) experiments followed by the isolation of lipoproteins and the subsequent analysis of their cholesterol content revealed that in vitro net esteriflcation of free cholesterol (FC) by LCAT as well as the fractional ufilization of HDL-FC as substrate were lower in the plasma of the aged animal as compared to that of the young animal despite the fact that the total pool of FC was higher in the former. The net transfer of FC from lower density lipoproteins (d<1.07 g/ml) to HDL provided the FC (in addition to HDL-FC) for esteriflcation in the plasma of both young and aged rats, and this process was not substantially affected by aging. Substrate specificity studies indicated that HDL from young rats was a better substrate for LCAT than the HDL from aged rats. The HDL isolated from the plasma of aged rats was enriched with apo E and had a considerably higher molecular weight than the HDL from young rat plasma. The ratio of phosphatidyl choline/sphingomyelin was lower in the HDL of aged rats. These data suggest that the decreased plasma cholesterol esteriflcation in aged rats is due to changes in the composition and size of the lipoprotein substrate (HDL).
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Govender, Gwensweri. "Fabrication and characterisation of eletrochemical biosensors for the determination of cholesterol." Thesis, View thesis, 2001. http://handle.uws.edu.au:8081/1959.7/461.
During the course of this study, an extensive investigation was conducted into the measurement of free and total cholesterol by fabrication of cholesterol biosensors. Specific areas investigated in-depth included the immobilisation of enzymes into conducting polypyrrole (PPy) film, bovine serum albumin-glutaraldehyde (BSA-GLA) gel and a hybrid bi-layer of PPy and BSA-GLA. Key parameters for the reliable measurement of cholesterol were optimised. The optimum parameters
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Donckers-Roseveare, Kathryn. "Periodic feedback to reduce cholesterol levels." Thesis, Virginia Tech, 1990. http://hdl.handle.net/10919/41912.
National Heart, Lung, and Blood Institute, ed. Facts about blood cholesterol. [Bethesda, Md.?: National Heart, Lung, and Blood Institute, National Institutes of Health], 1994.
National Heart, Lung, and Blood Institute, ed. Facts about--: Blood cholesterol. [Bethesda, Md.?: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health], 1987.
National Heart, Lung, and Blood Institute., ed. Facts about--: Blood cholesterol. [Bethesda, Md.?: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health], 1987.
Laker, Michael F. Understanding cholesterol. Poole, Dorset [England]: Family Doctor Publications in association with the British Medical Association, 2003.
Nicholson, Butkus Sue, Washington State University. Cooperative Extension., and United States. Dept. of Agriculture., eds. Eating to lower your blood cholesterol. Pullman [Wash.]: Cooperative Extension, College of Agriculture and Home Economics, Washington State University, 1989.
Central Health Services Council. Standing Medical Advisory Committee. Blood cholesterol testing: The cost-effectiveness of opportunistic cholesterol testing. [London]: Standing Medical Advisory Committee, 1990.
Jaranilla, Jawali, and Thomas E. Kottke. "Blood Cholesterol." In Encyclopedia of Immigrant Health, 284–88. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-5659-0_84.
Cohen Tervaert, Jan Willem. "Cholesterol and Modifications of Cholesterol in Rheumatic Disorders." In Inflammatory Diseases of Blood Vessels, 473–83. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118355244.ch43.
Heller, Lois Jane, Celette Sugg Skinner, A. Janet Tomiyama, Elissa S. Epel, Peter A. Hall, Julia Allan, Lara LaCaille, et al. "Total Cholesterol in the Blood." In Encyclopedia of Behavioral Medicine, 1985. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101802.
McNamara, Donald J. "Dietary Cholesterol and Blood Cholesterolemia: A Healthy Relationship." In World Review of Nutrition and Dietetics, 55–62. Basel: KARGER, 2009. http://dx.doi.org/10.1159/000235711.
Hulley, Stephen B. "Screening for High Blood Cholesterol: A Risky Business." In Cardiovascular Disease 2, 341–46. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1959-1_43.
Takano, T., C. Mineo, R. Hashida, Y. Yagyu-Mizuno, K. Nakagami, and S. Ohkuma. "Endothelial Injury and Accumulation of Cholesterol Ester Derived from Circulating Lipoproteins." In Role of Blood Flow in Atherogenesis, 231–36. Tokyo: Springer Japan, 1988. http://dx.doi.org/10.1007/978-4-431-68399-5_36.
Ogushi, Yoichi, Tomohito Hamazaki, and Yuko Kirihara. "Blood Cholesterol as a Good Marker of Health in Japan." In World Review of Nutrition and Dietetics, 63–70. Basel: KARGER, 2009. http://dx.doi.org/10.1159/000235712.
Crosby, Guy. "Managing healthy levels of blood glucose and cholesterol with konjac flour." In Gums and Stabilisers for the Food Industry 11, 338–41. Cambridge: Royal Society of Chemistry, 2007. http://dx.doi.org/10.1039/9781847551016-00338.
Тези доповідей конференцій з теми "Blood cholesterol":
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Prasad, D. N., Sumaya Al-Maadeed, Asan Abdul Muthalif, and Kishor Kumar Sadasivuni. "Optical Non-invasive Technique for Cholesterol Detection in Blood." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0076.
The aim of this research is to design and develop a non-invasive cholesterol sensor based on the principle of light absorption. The current existing invasive methods can be replaced with non-invasive techniques. The interaction of light with matter has been utilized to design a smart device that measures blood cholesterol without collecting blood samples. It requires developing an optical sensor that focuses on the use of near infrared (NIR)-LED.
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"The effect of cholesterol lowering drugs on vitamin D in people with family high blood cholesterol." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.83.
Gul, Burak Kursat, and Cetin Kurnaz. "Detection of high level cholesterol in blood with iris analysis." In 2016 20th National Biomedical Engineering Meeting (BIYOMUT). IEEE, 2016. http://dx.doi.org/10.1109/biyomut.2016.7849389.
Shen, Jiatong. "Research on the Correlation between Cholesterol Level, Diet, and Blood Pressure." In International Conference on Health Big Data and Intelligent Healthcare. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0011373400003438.
Martinakova, Z., J. Horilova, I. Lajdova, and A. Marcek Chorvatova. "Time-resolved fluorescence monitoring of cholesterol in peripheral blood mononuclear cells." In XIX Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics, edited by Agnieszka Popiolek-Masajada and Waclaw Urbanczyk. SPIE, 2014. http://dx.doi.org/10.1117/12.2074288.
Heiremans, J., M. Claeys, and A. G. Herman. "DETERMINATION OF CHOLESTERYL HYDROXYOCTADBCADIENOATES IN VASCULAR TISSUE BY HPLC AND ITS RELEVANCE TO ATHEROSCLEROSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643084.
Accumulation of lipids in the intimal arterial layer, and of cholesterol esters in particular, has been recognised as an early and prominent phenomenon in atherogenesis. Several attempts have been made to link putative peroxidation of these lipids in vivo to causal or deteriorating etiological determinants of plaque formation. The occurrence in advanced human atheromata of oxidized derivatives of cholesteryl linoleate -a major polyunsaturated cholesterol ester species in plasma and vessel wall - has been described by Brooks et al. (Atherosclerosis, 1970,13,223) and a positive correlation between the amount of cholesteryl hydroxyoctadecadienoates (CHODES) and the stage of the lesion has also been reported. In addition Funk and Powell (J. Biol. Chem., 1985,260,7481) have found hydroxyoctadecadienoic acids in normal aorta of different species, wich were strikingly increased after alkaline hydrolysis of total lipids, and this in contrast with the arachidonic acid analogs. The aim of this study was to develop a sensitive and practical method for specific assay of CHODES, without resorting to laborious saponification and derivatisation procedures required for gas chromatographic analysis, which could moreover augment the risk for artefacts.Dog thoracal aorta was homogenised and lipids were extracted using the Folch method with CHCl3/CH30H;2/l containing 0.05mM butylated hydroxytoluene. Fractionation of CHODES from neutral lipids was carried out by thin-layer chromatography. For detection and quantification a high-performance liquid chromatography (HPI/2) assay method was developed, with UV monitoring at 232nm , a wavelength characteristic for conjugated dienes with vicinal hydroxyl function. Reference compounds and the internal standard for HPLC analysis were synthesized from linoleic acid and 10,13,16-docosatrienoic acid, respectively, by preparation of hydroxy fatty acids with soybean lipoxygenase and subsequent esterification to cholesterol esters with pancreas cholesterol esterase. Confirmation of the structural identity was obtained by mass spectrometry. Artefactual formation of CHODES ex vivo was investigated by subjecting radiolabeled cholesteryl linoleate through the analysis procedure. This method allows the specific detection of CHODES in non-atherosclerotic arteries which was hitherto only reported for human advanced atherosclerotic lesions and is proposed as a sensitive and specific probe for prospective survey of lipid peroxidation in atherosclerotic blood vessels.
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Chang, Hsueh-Chia. "Micro-Fluidic Technologies for Blood Diagnostics." In ASME 2004 2nd International Conference on Microchannels and Minichannels. ASMEDC, 2004. http://dx.doi.org/10.1115/icmm2004-2315.
There is considerable market interest for miniature blood diagnostic kits for cholesterol, ovulation, glucose, bacteria, leukemia cells, coagulation tests, drugs etc. However, the presence of blood cells in the blood samples introduces an array of micro-fluidic issues that have become main obstacles to commercialization of these products. We discuss some of these anomalous micro-fluidic features of blood here. Some devices and designs developed at the Notre Dame Center for Micro-fluidics and Medical Diagnostics will be presented as solutions to these micro-fluidic challenges.
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Nishizawa, E. E., and D. J. Williams. "PERIVASCULAR CAROTID ARTERY INJURY LEAD TO ATHEROSCLEROSIS IN HYPERCHOLESTEROLEMIC RABBITS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643085.
We have previously shown that endothelial injury results when clotted blood is placed perivascularly around a rabbit carotid artery. This injury was manifested by loss of endothelial cells and adherence of leukocytes and platelets. When similar injury was induced in hypercholesterolemic rabbits, medial lesions as well as intimal proliferation was observed. We have extended these studies and have found that these lesions contain high concentrations of cholesterol (200-300 mg/gm protein compared to 40-80 mg/gm protein in controls) suggesting lipid infiltration. The uniformity of lipid accumulation along the injured tissue segment, which was measured as intimal thickening of serial sections, suggests that these lesions are not focal and that the injury was initiated by the perivascular blood rather than by mechanical injury. The contralateral non-injured vessels showed no lesions (0-2% of the total intima + media area) and normal cholesterol content. When the serum cholesterol level was decreased from about 1200 mg/dl to 450 mg/dl by use of drugs such as Colestid, the intimal proliferation was 8.9% compared to the untreated controls, which were around 36%. Aspirin, which did not lower serum cholesterol, had no effect on intimal proliferation and arterial cholesterol accumulation. These studies suggest that this model might be useful for evaluating antiatherosclerotic drugs.
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Schaub, R. G., and F. P. Bell. "LIPID ACCUMULATION AND METABOLISM IN CARRAGEENAN-INDUCED GRANULOMAS COMPARED TO BLOOD MONOCYTES AND THE AORTA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643410.
Arteries undergoing atherogenic change show an increase in cholesteryl esterifying activity by acylCoA:cholesterol acetyl-transferase (ACAT) and a progressive accumulation of cholesterol esters within monocyte derived foam cells. The study of these factors, however, is limited by the necessity of obtaining artery tissues for analysis. In this study, an in vivo model (Am J Path 118:134 and 120:391, 1985) which permits the analysis of foam cell development without requiring collection of aortas was examined in more detail. New Zealand rabbits (6 each) were either maintained on a 1% cholesterol/peanut oil diet (HD) or a regular chow diet (RD) for 2 weeks after which each had 15 ml of a 1% carra-geenan gel (Marine Colloids) injected subcutaneously into the mid-abdominal area. The rabbits were maintained on their respective diets for an additional 4 weeks. At sacrifice, blood was collected for both serum and monocyte isolation. Granulomas and aortic arches were also excised. Tissues were assayed for lipid accumulation and metabolism. Electron and light microscopy was also performed on immersion fixed (1% glutaraldehyde) granuloma tissue. Granulomas of HD rabbits were pale yellow and averaged 36 grams, while RD granulomas were a pale red and averaged 11 grams (p less than 0.05). RD granulomas did not stain with oil red 0. HD granulomas had homogenous oil red 0 staining which indicated lipid accumulation. Both RD and HD granulomas had large numbers of macrophages. RD macrophages accumulated follicular carrageenan, but not lipid. In HD granulomas, foam cell development was observed. Granuloma lipid content and metabolism paralleled the aorta and blood monocytes. The HD tissue had increased ACAT activity and lipid composition changes indicative of atherosclerosis. RD granulomas had no elevation of lipid content or ACAT activity. The results suggest that the carrageenan-induced granulomas provides a useful model for studying the biochemical and morphologic changes characteristic of aortic monocyte-derived foam cells and the early arterial atherosclerotic process.
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Jiang, Jingying, Lingling Zhang, Qiliang Gong, and Kexin Xu. "Influence of cholesterol on non-invasive blood glucose sensing studied with NIR spectroscopy." In SPIE BiOS. SPIE, 2011. http://dx.doi.org/10.1117/12.876191.
Gao, Hui, Chen Gong, Shi-chun Shen, Jia-ying Zhao, Dou-dou Xu, Fang-biao Tao, Yang Wang, and Xiao-chen Fan. A systematic review on the associations between prenatal phthalate exposure and childhood glycolipid metabolism and blood pressure: evidence from epidemiological studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0111.
Review question / Objective: The present systematic review was performed to obtain a summary of epidemiological evidence on the relationships of in utero exposure to phthalates with childhood glycolipid metabolism and blood pressure. Condition being studied: Childhood cardiovascular risk factors including blood pressure, lipid profile (e.g., triglycerides, total cholesterol, HDL−C, LDL−C) and glucose metabolism (e.g., insulin, insulin resistance, insulin sensitivity, glucose) were the interested outcomes. Eligibility criteria: In brief, epidemiological studies including cohort study, case-control study and cross-sectional survey were screened. Studies regarding relationships between human exposure to organophosphate esters and neurotoxicity were possible eligible for the present systematic review. The adverse neurodevelopmental outcomes included development of cognition, behavior, motor, brain change, emotion, etc. Studies that did not meet the above criteria were not included in this systematic review.
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Chen, Jiankun, Yingming Gu, Lihong Yin, Minyi He, Na Liu, Yue Lu, Changcai Xie, Jiqiang Li, and Yu Chen. Network meta-analysis of curative efficacy of different acupuncture methods on obesity combined with insulin resistance. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0075.
Review question / Objective: Population：Patients diagnosed as obesity with insulin resistance. Obesity reference: Consensus of experts on the Prevention and treatment of adult obesity in China in 2011 and Consensus of Chinese experts on medical nutrition therapy for overweight/obesity in 2016 were developed by the Obesity Group of Chinese Society of Endocrinology(CSE); BMI≥28. IR reference: According to the Expert opinions on insulin resistance evaluation published by Chinese Diabetes Society, HOMA-IR≥2.68 is regarded as the standard for the diagnosis of IR. Regardless of age, gender and course of disease. Patients diagnosed as obesity with insulin resistance. Intervention：Any kind of acupuncture, moxibustion, acupuncture+moxibustion, warm acupuncture, electropuncture, auricular point, acupoint application and acupoint catgut embedding. Comparison：Other acupuncture treatments, Drug therapy or blank control. Outcome：Primary outcomes: ①Fasting blood-glucose (FBG); ②Fasting serum insulin (FINS); ③Homeostasis model assessment-IR (HOMA-IR); ④Body Mass Index (BMI). Secondary outcomes: ①Waistline; ②Waist-hip ratio;③Triglyceride (TG); ④Total cholesterol (TC); ⑤High-density lipoprotein (HDL); ⑥Low-density lipoprotein (LDL). Study: Randomized controlled trials (RCTs) of different acupuncture methods in the treatment on obesity with insulin resistance, blind method and language are not limited. Randomized controlled trials (RCTs).
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The benefits of commonly used blood pressure and cholesterol lowering treatment can last 16 years. National Institute for Health Research, January 2019. http://dx.doi.org/10.3310/signal-000710.
Best Practices for Cardiovascular Disease Prevention Programs. National Center for Chronic Disease Prevention and Health Promotion, November 2022. http://dx.doi.org/10.15620/cdc:122281.
The Best Practices Guide for CVD Prevention describes and summarizes scientific evidence behind 8 effective strategies for lowering high blood pressure and cholesterol levels that can be implemented in health care systems and that involve community-clinical links. The guide is a resource for state and local health departments, decision makers, public health professionals, and other stakeholders interested in using proven strategies to improve cardiovascular health.
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Best Practices for Cardiovascular Disease Prevention Programs. National Center for Chronic Disease Prevention and Health Promotion (U.S.)., November 2022. http://dx.doi.org/10.15620/cdc:122290.
The Best Practices Guide for CVD Prevention describes and summarizes scientific evidence behind 8 effective strategies for lowering high blood pressure and cholesterol levels that can be implemented in health care systems and that involve community-clinical links. The guide is a resource for state and local health departments, decision makers, public health professionals, and other stakeholders interested in using proven strategies to improve cardiovascular health.
