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Статті в журналах з теми "Biologically Relevant Analytes"
Wu, Luling, Qingye Yang, Liyuan Liu, Adam C. Sedgwick, Alexander J. Cresswell, Steven D. Bull, Chusen Huang, and Tony D. James. "ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO−)." Chemical Communications 54, no. 61 (2018): 8522–25. http://dx.doi.org/10.1039/c8cc03717e.
Повний текст джерелаXu, Yifei, and Marco Bonizzoni. "Discrimination and Quantitation of Biologically Relevant Carboxylate Anions Using A [Dye•PAMAM] Complex." Sensors 21, no. 11 (May 24, 2021): 3637. http://dx.doi.org/10.3390/s21113637.
Повний текст джерелаDick, Jeffrey E., Adam T. Hilterbrand, Aliaksei Boika, Jason W. Upton, and Allen J. Bard. "Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring." Proceedings of the National Academy of Sciences 112, no. 17 (April 13, 2015): 5303–8. http://dx.doi.org/10.1073/pnas.1504294112.
Повний текст джерелаBaker, Gary A., Chase A. Munson, Eric J. Bukowski, Sheila N. Baker, and Frank V. Bright. "Assessment of One- and Two-Photon Excited Luminescence for Directly Measuring O2, pH, Na+, Mg2+, or Ca2+ in Optically Dense and Biologically Relevant Samples." Applied Spectroscopy 56, no. 4 (April 2002): 455–63. http://dx.doi.org/10.1366/0003702021955114.
Повний текст джерелаTerán-Alcocer, Álvaro, Francisco Bravo-Plascencia, Carlos Cevallos-Morillo, and Alex Palma-Cando. "Electrochemical Sensors Based on Conducting Polymers for the Aqueous Detection of Biologically Relevant Molecules." Nanomaterials 11, no. 1 (January 19, 2021): 252. http://dx.doi.org/10.3390/nano11010252.
Повний текст джерелаPeltomaa, Riikka, Bettina Glahn-Martínez, Elena Benito-Peña, and María Moreno-Bondi. "Optical Biosensors for Label-Free Detection of Small Molecules." Sensors 18, no. 12 (November 24, 2018): 4126. http://dx.doi.org/10.3390/s18124126.
Повний текст джерелаCrapnell, Robert, Alexander Hudson, Christopher Foster, Kasper Eersels, Bart Grinsven, Thomas Cleij, Craig Banks, and Marloes Peeters. "Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection." Sensors 19, no. 5 (March 9, 2019): 1204. http://dx.doi.org/10.3390/s19051204.
Повний текст джерелаRedy-Keisar, Orit, Einat Kisin-Finfer, Shiran Ferber, Ronit Satchi-Fainaro, and Doron Shabat. "Synthesis and use of QCy7-derived modular probes for the detection and imaging of biologically relevant analytes." Nature Protocols 9, no. 1 (December 5, 2013): 27–36. http://dx.doi.org/10.1038/nprot.2013.166.
Повний текст джерелаGonzález-Ruiz, Víctor, Jegathalaprathaban Rajesh, Ana I. Olives, Damiano Rocchi, Jorge Gómez-Carpintero, Juan F. González, Vellaisamy Sridharan, M. Antonia Martín, and J. Carlos Menéndez. "Antioxidants as Molecular Probes: Structurally Novel Dihydro-m-Terphenyls as Turn-On Fluorescence Chemodosimeters for Biologically Relevant Oxidants." Antioxidants 9, no. 7 (July 10, 2020): 605. http://dx.doi.org/10.3390/antiox9070605.
Повний текст джерелаGranzhan, Anton, Heiko Ihmels, and Maoqun Tian. "The benzo[b]quinolizinium ion as a water-soluble platform for the fluorimetric detection of biologically relevant analytes." Arkivoc 2015, no. 6 (December 1, 2015): 494–523. http://dx.doi.org/10.3998/ark.5550190.p009.339.
Повний текст джерелаДисертації з теми "Biologically Relevant Analytes"
Palisi, Angelica. "NMR-based metabolomic analysis of biological fluids to monitor relevant unsolved diseases." Doctoral thesis, Universita degli studi di Salerno, 2017. http://hdl.handle.net/10556/2565.
Повний текст джерелаMetabolomics and metabonomics encompass the comprehensive profiling of multiple metabolite concentrations and their cellular and systemic fluctuations in response to drugs, diet, lifestyle, environment, stimuli and genetic modulations, in order to characterize the beneficial and adverse effects of such interactions. In the context of biomedical applications, metabolomics will have a preferential role with respect to the other "Omics" sciences for its ability to detect in real time the response of the organisms to pathological stressors. The application of the NMR technique for the metabolomics analysis was applied to bio-fluids deriving from populations of patients respectively affected by salivary gland tumor, antiphospholipid autoimmune syndrome and altered lipid profile. This NMR metabolomic screening was aimed i) at the definition of a metabolomic profile that may be patognomonic of the disease under scrutiny and ii) at the identification of biomarkers to be used with diagnostic and prognostic scope. In the present work, we present a NMR-based metabolomic study of saliva of patients suffering of salivary gland tumors. Our data show that individuals suffering parotid tumor have a characteristic metabolomic profile with abnormalities associated to the metabolism of acetate, alanine, lactate, methanol, phenylalanine, propionate, succinate. We have identified for the first time the metabolomic fingerprint characterizing parotid tumor patients disease having potential application to improve timely diagnosis and appropriate therapeutic approaches. Salivary gland tumor, as many other cancers, is a complex disease, resulting from an interdependent series of biochemical alterations, rather than a single disruptive event. In this case our approach aimed at the identification of a panel of metabolite markers rather than a single biomarker, will improve the sensitivity and specificity for detection. Integrating the protocols of tumor grading and histological classification. Our NMR-based metabolomic study revealed different metabolomic profiles in saliva of male patients affected by salivary gland tumors compared with the profiles of age, gender, and sampling-date matched control individuals. Our approach provide preliminary data for the identification of metabolites that can be used as metabolomics fingerprint of salivary gland tumor. Determination of metabolomics fingerprint, rather than single metabolic biomarker, may fully reflect the multifactorial nature of oncogenesis and the heterogeneity of oncogenic pathways, providing precious elements to integrate diagnostic laboratory and clinical tests. Antiphospholipid syndrome (APS) is a rheumatic inflammatory chronic autoimmune disease inducing hypercoagulable state associated with vascular thrombosis and pregnancy loss in women. Cardiac, cerebral and vascular strokes in these patients are responsible for reduction in life expectancy. Timely diagnosis and accurate monitoring of disease is decisive to improve the accuracy of therapy. In the present work, we present a NMR-based metabolomic study of blood sera of APS patients. Our data show that individuals suffering APS have a characteristic metabolomic profile with abnormalities associated to the metabolism of methyl group donors, ketone bodies and amino acids. We have identified for the first time the metabolomic fingerprint characterizing APS disease having potential application to improve APS timely diagnosis and appropriate therapeutic approaches. The first stratification of APS patients according to the gender offers preliminary indications for the management of the disease according to the gender oriented medicinal approach. Human serum includes a large number of components which derive from endogenous metabolism and nutritional intake. Serum components vary in response to diet. Serum lipid composition is probably the most important benchmark in assessing cardiovascular risk and disease progression. Serum components, also derived from nutritional intake, can affect general metabolism and, more specifically, affect molecular mechanisms and pathways linking nutritional intake and chronic disease risk. To identify the effect exerted by altered lipid composition on the genome expression pattern, response of gene expression to serum samples from hypercholesterolemic and normocholesterolemic male subjects was previously studied. In the present part of my PhD thesis, using a NMR metabolomics approach I studied the metabolomics profile of the aforementioned hypercholesterolemic and normocholesterolemic sera to correlate the previously identified trascriptomic signature of human hepatoma cells to the relative metabolomics profile. Hypercholesterolemic sera previously proved to increase in human hepatoma cells, the mRNA expression of HMGCS2, an enzyme involved in the pathway of keton bodies. Our NMR based metabolomics analysis evidences abnormal concentrations of metabolites involved in the keton bodies pathway. This indicates a correlation between the trascriptomic profile of hepatoma cells treated with hypercholesterolemic sera, and the metabolomics profile of the same sera. [edited by author]
La metabolomica e la metabonomica comprendono il profilo completo di numerosi metaboliti con riferimento alle varie concentrazioni e fluttuazioni sia cellulari che sistemiche in risposta a farmaci, dieta, stile di vita, influenza dell'ambiente, stimoli e modulazioni genetiche, al fine di caratterizzare gli effetti benefici e negativi di tali interazioni. Nel contesto delle applicazioni biomediche, la metabolomica avrà in futuro un ruolo preferenziale rispetto alle altre scienze 'omiche' per la possibilità di rilevare in tempo reale la risposta degli organismi agli stress patologici. L' applicazione della tecnica NMR è stata utilizzata per l' analisi metabolomica di bio-fluidi derivanti da popolazioni di pazienti affetti rispettivamente da tumore delle ghiandole salivari; da sindrome da antifosfolipidi; pazineti con profilo lipidico alterato. Questo screening metabolomico NMR è mirato i) alla definizione di un profilo metabolomico che potrebbe essere patognomonico delle malatte monitorate e ii) l'identificazione di biomarcatori da utilizzare in ambito diagnostico e prognostico. In questo studio metabolomico basato su analisi NMR della saliva di pazienti affetti dai tumori delle ghiandole salivari i nostri dati mostrano caratteristiche anomalie nel profilo metabolomico connesse con il metabolismo di acetato , alanina, lattato, metanolo, fenilalanina, propionato, succinato. Abbiamo identificato per la prima volta l'impronta digitale metabolomica che caratterizza pazienti con tumori della parotide con una potenziale applicazione per migliorare la diagnosi tempestiva ed un approccio terapeutico adeguato. I tumori alle ghiandole salivari, come molti altri tipi di cancro, sono patologie complesse, risultanti da una serie interdipendente di alterazioni biochimiche, piuttosto che un singolo evento dirompente. In questo caso, con un approccio rivolto all'identificazione di un panel di metaboliti marcatori, piuttosto che ad un singolo biomarcatore, miglioreranno ed aumenteranno la sensibilità e la specificità per il rilevament, integrando i protocolli diagnostici classici e la classificazione istologica. Il nostro studio metabolomico NMR-based ha rivelato diversi profili nella saliva di pazienti affetti da tumori delle ghiandole salivari, confrontati in base all' età e al sesso, abbinati con i controlli. Il “finger print”, piuttosto che i singoli biomarkers, può riflettere in pieno la natura multifattoriale ed etrogenea della oncogenesi , fornendo preziosi elementi per integrare i test diagnostici clinici e di laboratorio. La sindrome antifosfolipidi (APS) è una malattia autoimmune, reumatica, infiammatoria cronica associata ad uno stato di ipercoagulabilità: inducendo trombosi vascolari ed aborti spontaeni nelle donne. Ictus cerebrali e vascolari in questi pazienti sono responsabili della riduzione della aspettativa di vita: una diagnosi tempestiva ed un accurato monitoraggio della malattia è determinante per migliorare la precisione della terapia. Nel presente lavoro, vi presentiamo uno studio di metabolomica NMR su siero di pazienti affetti da APS. I nostri dati mostrano che gli individui che soffrono di APS hanno un profilo metabolomico caratteristico con anomalie del metabolismo associate ai donatori di gruppi metilici, di aminoacidi e corpi chetonici. Abbiamo identificato per la prima volta il “finger print” della sindrome da APS con la potenziale applicazione di migliorare la diagnosi tempestiva e favorire un approccio terapeutico adeguato. La prima stratificazione di pazienti APS pazienti in base al sesso offre indicazioni per la gestione della malattia secondo un approccio medico gender oriented. Il siero umano comprende un gran numero di componenti derivanti sia dal metabolismo endogeno sia dall' apporto nutrizionale i quali variano in risposta alla dieta. La composizione lipidica del siero è probabilmente il punto di riferimento più importante nella valutazione del rischio cardiovascolare e della progressione della malattia. Inoltre la composizione lipidica può influenzare il metabolismo e più in particolare, i percorsi molecolari che collegano l' apporto nutrizionale ed rischio di malattia cronica. L'effetto esercitato dalla composizione lipidica modificata sul pattern genomico in risposta all' espressione su campioni di siero da sogetti maschi ipercolesterolemici, confrontati con normocholesterolemici è stato oggetto di un precedente studio. Nell' ultimaparte di questa tesi di dottorato, utilizzando l'approccio metabolomico NMR ho studiato il profilo dei supramenzionati ipercolesterolemici e normocholesterolemici per correlare il profilo trascrittomico ottenuto dalle cellule epatiche umane con il profilo metabolomico del siero umano utilizzato per la cultura, mostrando una aumentata espressione di mRNA di HMGCS2, un enzima coinvolto nel percorso di corpi chetonici. Dall' analisi NMR sono emerse concentrazioni alterate di metaboliti coinvolti della via biosintetica dei corpi chetonici. Questo indica una correlazione tra il profilo trascriptomico di cellule epatiche trattate con sieri ipercolesterolemici, e il profilo metabolomica dei sieri stessi. [a cura dell'autore]
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Goolsby, Brian James. "Techniques for improved mass spectrometric analysis of biologically relevant molecules produced by MALDI and ESI in the quadrupole ion trap /." Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004273.
Повний текст джерелаGiacopelli, Brian John. "Global DNA methylation analysis of chronic lymphocytic leukemia and acute myeloid leukemia reveals distinct clinically relevant biological subtypes." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1591114255694166.
Повний текст джерелаMichel, Yvonne [Verfasser], and Reinhard [Akademischer Betreuer] Bredehorst. "Structural and functional analyses of IgE epitopes and their biological relevance / Yvonne Michel. Betreuer: Reinhard Bredehorst." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2012. http://d-nb.info/1024772802/34.
Повний текст джерелаKaraminkov, Rosen. "Conformations and fragmentation of biologically relevant molecules and their binary complexes with water probed by high resolution UV and mass analyzed threshold ionization spectroscopy." kostenfrei, 2009. https://mediatum2.ub.tum.de/node?id=821610.
Повний текст джерелаStevens, Anna L. (Anna Lea). "Mechanical injury and inflammatory cytokines affect cartilage integrity and tissue homeostasis : a mass spectrometric analysis of proteins with relevance to arthritis." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37956.
Повний текст джерелаIncludes bibliographical references.
Osteoarthritis is characterized by synovial joint degeneration, and its cardinal pathological feature is degeneration and loss of the articular cartilage joint surface. While the aetiology of osteoarthritis is unknown, risk factors include gender, age, obesity, and prior joint injury. Joint injuries, including tears of the anterior cruciate ligament (ACL) and meniscus, increase the risk for the development of OA and involve both mechanical damage to cartilage, meniscus and synovial tissues, and tissue degradation associated with cytokine-induced inflammation. While the role of inflammatory cytokines in OA is still controversial, their role in rheumatoid arthritis is evidenced by the successful use of anti-TNF-ca and anti-IL-1 therapies to abrogate disease symptoms and progression. In vitro, both IL-13 and TNF-ca promote chondrocyte-mediated matrix degradation and inhibit cartilage matrix synthesis, while mechanical damage causes cell death, matrix damage, and decreased cell biosynthesis. Understanding the similarities and differences in cartilage responses to inflammatory cytokines and mechanical injury is important in understanding the catabolic-anabolic shifts that typify OA progression. Therefore, the objectives of this thesis were (1) to identify the role of TNF-a and IL-1 induced nitric oxide (NO) as a mediator of cartilage tissue damage;
(cont.) (2) to characterize and compare the regulation by IL- 1 P, TNF-cc, and mechanical injury of secreted factors, matrix degradation, and mechanisms of chondrocyte cell death using an SDS-PAGE-LC/MS/MS protein profiling approach; and (3) to further quantify the effects of IL-1 3, TNF-ca and injury using an isobaric isotope labeling (iTRAQ) based 2D-LC/MS/MS approach. Together these studies were designed to provide better understanding of matrix degradation, cell death, immune response, and evidence of cell-mediated repair processes. NO is produced by chondrocytes in response to inflammatory cytokines TNF-a, IL-1 3 and IL-17, and can mediate cellular and extracellular events through cGMP signaling, protein modifications (e.g., S-nitrosation or tyrosine nitration), altered transcript stability, and altered sugar and lipid chemistry. Cartilage was treated with IL-13 or TNF-ca left untreated in the presence or absence of the NO synthase inhibitor, L-N-methylarginine (L-NMA), and changes in gene expression and matrix breakdown were measured. We found that L-NMA treatment partially inhibited TNF-a-induced, aggrecanase-mediated aggrecan degradation as indicated by a decrease in sGAG loss to the medium and by an increase in the generation of aggrecanase-specific aggrecan fragments.
(cont.) No change was observed upon addition of L-NMA to IL- 1P treated explants, but addition of L-NMA to combined IL-1 3 and TNF-a treated explants increased sGAG loss, suggesting that the effects of NO may be contextual. We hypothesized that this might be due to differences in aggrecanase expression (ADAMTS4 vs. ADAMTS5) or post-translational modification, but no aggrecanase was consistently identified in the samples. No difference in MMP expression or activation was noted following addition of L-NMA, and no change in NO chemistry between IL-1 3 and TNF-a treatment was evident by nitrate and nitrite production. Gene expression analysis was conducted on a battery of 32 genes, including matrix proteins, inflammatory mediators, proteases, cytokines and growth factors, and housekeeping proteins. While IL-113 and TNF-a both increased the expression of proteases and inflammatory mediators, addition of L-NMA did not significantly affect expression of the genes tested. We concluded that the effects of TNF-a and IL-1 p-induced NO production may depend on differences in cellular responses to each of these cytokines and possibly to differences in signaling or aggrecanase expression.
(cont.) In the second study, newborn bovine calf cartilage explants were treated with 10 ng/ml IL-1 p, 100 ng/ml TNF-a, radially-unconfined injurious compression (strain: 50%; strain rate 1000/o/sec), or no treatment, and cultured for five days. Pooled medium was subjected to SDS-PAGE-LC/MS/MS, and data were analyzed by Spectrum Mill proteomics software, focusing on protein identification, differences between treatments and matrix protein proteolysis. Over 250 proteins were identified among the four protein groups including CD 109, platelet derived growth factor like protein, and scrapie responsive protein, which have not been previously identified in cartilage. IL-13 and TNF-a caused an increase in YKL39, YKL40, complement factor B, MMP-3, ECM-1, haptoglobin, serum amyloid A3, and clusterin. Injurious compression caused the release of intracellular proteins including GRP58, GRP78, alpha 4 actinin, pyruvate kinase, and vimentin, suggesting a loss of membrane integrity in a population of chondrocytes. Data on actin release within the first 24 hours suggested that this loss of membrane integrity occurred by mechanical cell disruption. Injurious compression also caused proteolysis of collagen type VI subunits, collagen type II, and COMP. Thrombospondin 1 fragments were seen in all treatment groups, and aggrecan proteolysis was predominant with cytokine treatment.
(cont.) Cartilage explants subjected to injurious compression released intracellular proteins and showed enhanced degradation of matrix proteins, while explants subjected to IL- 13 or TNF-ct released proteins involved in innate immunity and stress response. In the third study, cartilage explants were subjected to injurious compression, TNF-a (100 ng/ml) or IL-13 (10 ng/ml), or no treatment, cultured in equal volumes of medium, and the medium was collected, pooled and the proteins deglycosylated by treatment with chondroitinase ABC. The proteins were subjected to trypsinization, and the peptides were labeled with one of four iTRAQ labels each containing a unique signature ion. The labeled peptides were subjected to nano-2D-LC/MS/MS on a QStar, quadrupole time of flight instrument. The study was done in analytical replicate on a pooled sample of greater than 70 explants from a total of 6-12 different animals. Data were analyzed by ProQuant to obtain a ProGroup peptide report containing identified spectra, which were combined to achieve a peptide, and then a protein level output of mean ratios, standard deviations of those ratios, and significance based on either Wilcoxan sign rank or Student's t-test both corrected for multiple comparisons.
(cont.) Because of our interest in catabolic and anabolic shifts, a targeted data analysis approach was taken in addition to a systems level PCA and K-means clustering approach. By focusing on particular protein domains, we identified a decrease in the synthesis of most fibrillar collagen subunits (p<0.05), and an increase in the release of the aggrecan G2 and G3 domains with IL-13 and TNF-ta treatment (p<0.05). We also noted a significant increase in MMP-1, MMP-3, MMP-9, and MMP-13 in at least one condition and, in most cases, all conditions compared to the untreated sample. Increases in proteins involved in innate immunity and immune cell recruitment were noted with IL-1 [3 and TNF-a treatment, while an increase in intracellular protein release was seen most dramatically with mechanical compression injury. Since anabolic effects are often driven by the insulin-like growth factor family and the TGF-[3 superfamily, we specifically identified members of these pathways to understand which factors may mediate early repair processes.
(cont.) At the systems level, 2 principal components were sufficient to describe 97% of the covariance in the data. IL- 1 and TNF-a caused a similar response in proteins identified; in contrast, a 'Y'-shaped distribution was observed upon projection of proteins based on their response injury vs. cytokine treatment. K-means clustering revealed six main clusters to further characterize the biology of mechanical injury versus cytokine effects on cartilage.
by Anna L. Stevens.
Ph.D.
Georgiev, Stoyan G. [Verfasser], Hans Jürgen [Akademischer Betreuer] Neusser, and Klaus [Akademischer Betreuer] Köhler. "Mass Analyzed Threshold Ionization Studies and Quantum-Chemical Calculations of Biologically Relevant Molecules and Hydrogen-Bonded Complexes / Stoyan Georgiev. Gutachter: Klaus Köhler. Betreuer: Hans Jürgen Neusser." München : Universitätsbibliothek der TU München, 2011. http://d-nb.info/101959005X/34.
Повний текст джерелаFerhatosmanoglu, Nilgun. "Optimal design of experiments for emerging biological and computational applications." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1179177867.
Повний текст джерелаMartins, Joana Mafalda Nunes Paulo Silva. "Supramolecular Sensors and Actuators for Biologically Relevant Analytes." Master's thesis, 2020. http://hdl.handle.net/10362/111125.
Повний текст джерелаIn the field of biochemistry, the study of peptides is of great interest, not only due to the variety of functions these molecules present in biological systems (e.g. in signalling, neuromodulation, immune response and metabolism) but also as tools in biotechnology and as pharmaco-logical agents, as is the case of antimicrobial cell-penetrating peptides. Supramolecular receptors have had a rising application in the transport, modulation and sensing of these biomolecules, due to the strong interactions they can establish with affinities up to the nM range. In this thesis, a group of supramolecular dual emission sensors and a light-controlled transporter for cationic peptides were synthesized and characterized. These consist of a modular amphiphilic system based on a p-sulfonatocalix[4]arene receptor, monosubstituted in its lower rim with different functional groups, depending on the target application. The sensors SCnPy present an aliphatic chain of variable size (n = 4, 6), with a pyrene fluorescent moiety at its end, while the transporter SC6Azo presents a six-carbon aliphatic chain with an azobenzene moiety. SCnPy have shown to have the pyrene’s characteristic monomer emission at low concentration and, when at high enough concentrations or in the presence of organic cations, they can form ground state dimers that emit at higher wavelengths. The variation of chain length successfully modulated the capacity of the SCnPy sensors to aggregate. SC4Py showed this dual emission for polyarginines of four or more residues, presenting a critical aggregation concentration (CAC) of 9.8 μΜ for a 1:2 molar ratio of sensor to a six-residue polyarginine. SC6Py is able to aggregate in the presence of peptides with only 3 cationic residues, with CAC of 0.11 μM, with the same peptide and in the same conditions as for SC4Py. Furthermore, SC6Py showed selectivity for a fragment of the peptide Humanin, over a similar sequence of another mitochondrial signaling peptide, SHLP4, all the while presenting a dual emission that enables the correction of the measurement for instrumental factors and sensor concentration variations. Other phenomena and modes of detection (resonance energy transfer and dye displacement assays) were also explored for the SCnPy system. The light-controlled transporter, SC6Azo, also binds to polyarginines and presents an efficient light induced isomerization, with quantitative photochemical conversion from trans to cis, when irradiated at 382 nm, and reaching 73% of maximum conversion for the reverse reaction, upon irradiation at 500 nm. This enabled a great decrease in polarity of the tail, when irradiating the cis isomer and converting it to trans, showing a maximum increase of peptide transport in phosphatidylcholine liposomes of, approximately, 30%.
Dey, Nilanjan. "Engaging Small Organic Molecules and Self-Assemblies for ‘Label-Free’ Recognition of Biologically Relevant Analytes." Thesis, 2016. https://etd.iisc.ac.in/handle/2005/4908.
Повний текст джерелаКниги з теми "Biologically Relevant Analytes"
E, Merian, ed. Metals and their compoundsin the environment: Occurrence, analysis, and biological relevance. Weinheim: VCH, 1991.
Знайти повний текст джерелаE, Merian, and Clarkson Thomas W, eds. Metals and their compounds in the environment: Occurrence, analysis, and biological relevance. Weinheim: VCH, 1991.
Знайти повний текст джерелаAnke, M. Elements and their compounds in the environment: Occurrence, analysis and biological relevance. 2nd ed. Weinheim: Wiley-VCH, 2004.
Знайти повний текст джерелаM, Anke, Ihnat M, and Stoeppler M. 1927-, eds. Elements and their compounds in the environment: Occurence, analysis and biological relevance. 2nd ed. Weinheim: Wiley-VCH, 2004.
Знайти повний текст джерелаDovigi, Stephanie. An Analysis of the performance of molecular mechanics methods in the study of some biologically relevant hydrogen-bonded systems. Sudbury, Ont: Laurentian University, 1993.
Знайти повний текст джерелаSmetanin, Anatoliy. Formation and structure of the biota of Kamchatka's natural ecosystems. ru: INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1316649.
Повний текст джерелаAgafonov, Vyacheslav, Sergey Bogolyubov, Liya Vasil'eva, Galina Vyphanova, Dmitriy Gorohov, Natal'ya Zhavoronkova, Inna Ignat'eva, et al. Sources of environmental law. ru: INFRA-M Academic Publishing LLC., 2022. http://dx.doi.org/10.12737/1913253.
Повний текст джерелаMerian, Ernest. Metals and Their Compounds in the Environment: Occurrence, Analysis, and Biological Relevance. Wiley-VCH, 1990.
Знайти повний текст джерела(Editor), Ernest Merian, Manfred Anke (Editor), Milan Ihnat (Editor), and Markus Stoeppler (Editor), eds. Elements and their Compounds in the Environment: Occurrence, Analysis and Biological Relevance. 2nd ed. Wiley-VCH, 2004.
Знайти повний текст джерелаLentzos, Filippa. Genetic Engineering and Biological Risks. Edited by Roger Brownsword, Eloise Scotford, and Karen Yeung. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199680832.013.66.
Повний текст джерелаЧастини книг з теми "Biologically Relevant Analytes"
Głowacki, Rafał, Justyna Piechocka, Edward Bald, and Grażyna Chwatko. "Application of Separation Techniques in Analytics of Biologically Relevant Sulfur Compounds." In Handbook of Bioanalytics, 233–56. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-95660-8_11.
Повний текст джерелаGłowacki, Rafał, Justyna Piechocka, Edward Bald, and Grażyna Chwatko. "Application of Separation Techniques in Analytics of Biologically Relevant Sulfur Compounds." In Handbook of Bioanalytics, 1–24. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-63957-0_11-1.
Повний текст джерелаOoi, Chia Huey, Madhu Chetty, and Shyh Wei Teng. "Relevance, Redundancy and Differential Prioritization in Feature Selection for Multiclass Gene Expression Data." In Biological and Medical Data Analysis, 367–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11573067_37.
Повний текст джерелаTashiro, Hironori, Manabu Fukumoto, Kohji Miyazaki, and Hitoshi Okamura. "Biological Relevance and Analysis of c-myc Gene Expression in Normal Human Ovary." In Molecular Basis of Reproductive Endocrinology, 243–49. New York, NY: Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-9260-6_20.
Повний текст джерелаWang, Yajie, Lufeng Wang, Chuanjiang Dong, Li Li, Mengqi Tang, Weizhong Sun, and Yao Wu. "Evaluation of Uncertainty for Determination of Trace Uranium in Biology by Laser Fluorescence Method." In Springer Proceedings in Physics, 549–66. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-1023-6_48.
Повний текст джерелаKodali, Surya T., Philip Kauffman, Sainath R. Kotha, Anita Yenigalla, Rengasayee Veeraraghavan, Sonal R. Pannu, Thomas J. Hund, et al. "Oxidative Lipidomics: Analysis of Oxidized Lipids and Lipid Peroxidation in Biological Systems with Relevance to Health and Disease." In Measuring Oxidants and Oxidative Stress in Biological Systems, 61–92. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-47318-1_5.
Повний текст джерелаDissmeyer, Nico, and Arp Schnittger. "Use of Phospho-Site Substitutions to Analyze the Biological Relevance of Phosphorylation Events in Regulatory Networks." In Methods in Molecular Biology, 93–138. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-264-9_6.
Повний текст джерелаJamrozik, Euzebiusz, and Michael J. Selgelid. "Drug-Resistant Infection: Causes, Consequences, and Responses." In Ethics and Drug Resistance: Collective Responsibility for Global Public Health, 3–18. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-27874-8_1.
Повний текст джерелаMoosavi, Sanaz Rahimi, and Arman Izadifar. "End-to-End Security Scheme for E-Health Systems Using DNA-Based ECC." In Silicon Valley Cybersecurity Conference, 77–89. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-96057-5_6.
Повний текст джерелаHale, Robert C., Meredith E. Seeley, Ashley E. King, and Lehuan H. Yu. "Analytical Chemistry of Plastic Debris: Sampling, Methods, and Instrumentation." In Microplastic in the Environment: Pattern and Process, 17–67. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78627-4_2.
Повний текст джерелаТези доповідей конференцій з теми "Biologically Relevant Analytes"
Quesada-Moreno, María, Melanie Schnell, and Anna Krin. "CHIRAL ANALYSIS OF BIOLOGICALLY RELEVANT SAMPLES USING BROADBAND ROTATIONAL SPECTROSCOPY." In 73rd International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2018. http://dx.doi.org/10.15278/isms.2018.tc05.
Повний текст джерелаVattam, Swaroop S., and Ashok K. Goel. "Foraging for Inspiration: Understanding and Supporting the Online Information Seeking Practices of Biologically Inspired Designers." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48238.
Повний текст джерелаCelli, Jonathan P., Imran Rizvi, Adam R. Blanden, Adnan O. Abu-Yousif, Bryan Q. Spring, and Tayyaba Hasan. "Biologically relevant 3D tumor arrays: imaging-based methods for quantification of reproducible growth and analysis of treatment response." In SPIE BiOS, edited by David H. Kessel and Tayyaba Hasan. SPIE, 2011. http://dx.doi.org/10.1117/12.876149.
Повний текст джерелаSevinsky, Chris, Alberto Santamaria-Pang, Jingyu Zhang, Christina Lowes, Dipen Sangurdekar, Beverly Falcon, Qing Li, et al. "Abstract 1709: Quantification of biologically relevant vascular phenotypes in human prostate cancer: automated image analysis using hyperplexed immunofluorescence." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1709.
Повний текст джерелаSemenov, V. G. "THE RELEVANCE OF THE APPLICATION OF BIOLOGICALLY ACTIVE COMPLEXES IN THE NEONATAL PERIOD IN CALVES GROWING." In DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE: EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-21.
Повний текст джерелаShen, Zhuohua, and Justin Seipel. "A Simple Analytical Tool for Legged Robot Design." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-71452.
Повний текст джерелаHolt, Jeremiah R., Heejoon Jo, Vonn Walter, Xiaobei Zhao, David Neil Hayes, and Yoon Ho Ko. "Abstract 5448: Integrative analysis of microRNA expression identifies two biologically distinct and clinically relevant subtypes of head and neck squamous cell carcinoma." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-5448.
Повний текст джерелаJames, Angela. "BIOLOGICAL SCIENCES PRE-SERVICE TEACHERS' EXPERIENCES OF COVID-19 AS AN ENABLER FOR THEIR SERVICE-LEARNING PROJECTS." In SCIENCE AND TECHNOLOGY EDUCATION: DEVELOPING A GLOBAL PERSPECTIVE. Scientia Socialis Ltd., 2021. http://dx.doi.org/10.33225/balticste/2021.86.
Повний текст джерелаCooper, Kathryn, Prasuna Vemuri, and Hesham Ali. "On the comparison of state- and transition-based analysis of biological relevance in gene co-expression networks." In 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2015. http://dx.doi.org/10.1109/bibm.2015.7359852.
Повний текст джерелаAlmeida, Henrique A., and Paulo J. Ba´rtolo. "The Use of Schwartz Geometries for Scaffold Design in Tissue Engineering Applications." In ASME 2010 10th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2010. http://dx.doi.org/10.1115/esda2010-25385.
Повний текст джерелаЗвіти організацій з теми "Biologically Relevant Analytes"
Jones, Robert, Molly Creagar, Michael Musty, Randall Reynolds, Scott Slone та Robyn Barbato. A 𝘬-means analysis of the voltage response of a soil-based microbial fuel cell to an injected military-relevant compound (urea). Engineer Research and Development Center (U.S.), листопад 2022. http://dx.doi.org/10.21079/11681/45940.
Повний текст джерелаWang, Xiaoyue, Hui Lu, Zhihao Liang, Liang Wang, and Ji Ma. Ixazomib combined with autologous stem cell transplantation for POEMS syndrome: a case report and meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2022. http://dx.doi.org/10.37766/inplasy2022.7.0061.
Повний текст джерелаSavosko, V., I. Komarova, Yu Lykholat, E. Yevtushenko, and T. Lykholat. Predictive model of heavy metals inputs to soil at Kryvyi Rih District and its use in the training for specialists in the field of Biology. IOP Publishing, 2021. http://dx.doi.org/10.31812/123456789/4511.
Повний текст джерелаСавосько, Василь Миколайович, Ірина Олександрівна Комарова, Юрій Васильович Лихолат, Едуард Олексійович Євтушенко,, and Тетяна Юріївна Лихолат. Predictive Model of Heavy Metals Inputs to Soil at Kryvyi Rih District and its Use in the Training for Specialists in the Field of Biology. IOP Publishing, 2021. http://dx.doi.org/10.31812/123456789/4266.
Повний текст джерелаBelkin, Shimshon, Sylvia Daunert, and Mona Wells. Whole-Cell Biosensor Panel for Agricultural Endocrine Disruptors. United States Department of Agriculture, December 2010. http://dx.doi.org/10.32747/2010.7696542.bard.
Повний текст джерелаMawassi, Munir, and Valerian Dolja. Role of RNA Silencing Suppression in the Pathogenicity and Host Specificity of the Grapevine Virus A. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7592114.bard.
Повний текст джерелаGottlieb, Yuval, Bradley Mullens, and Richard Stouthamer. investigation of the role of bacterial symbionts in regulating the biology and vector competence of Culicoides vectors of animal viruses. United States Department of Agriculture, June 2015. http://dx.doi.org/10.32747/2015.7699865.bard.
Повний текст джерелаLers, Amnon, Majid R. Foolad, and Haya Friedman. genetic basis for postharvest chilling tolerance in tomato fruit. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7600014.bard.
Повний текст джерелаAvni, Adi, and Gitta L. Coaker. Proteomic investigation of a tomato receptor like protein recognizing fungal pathogens. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600030.bard.
Повний текст джерелаShmulevich, Itzhak, Shrini Upadhyaya, Dror Rubinstein, Zvika Asaf, and Jeffrey P. Mitchell. Developing Simulation Tool for the Prediction of Cohesive Behavior Agricultural Materials Using Discrete Element Modeling. United States Department of Agriculture, October 2011. http://dx.doi.org/10.32747/2011.7697108.bard.
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