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Добірка наукової літератури з теми "Bacteriophages"

Автор: Grafiati
Опубліковано: 4 червня 2021
Оновлено: 30 липня 2024

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Статті в журналах з теми "Bacteriophages"

1

Samir, Safia. "Bacteriophages as Therapeutic Agents: Alternatives to Antibiotics." Recent Patents on Biotechnology 15, no. 1 (May 7, 2021): 25–33. http://dx.doi.org/10.2174/1872208315666210121094311.

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Анотація:
: Bacteriophages are bacterio-specific viruses that constitute the main portion of the environment. Bacteriophages inject their genome into the targeted bacterial cells and some of them can disrupt the metabolism of bacteria and cause bacterial cell disintegration. The application of bacteriophages to kill bacteria is known as bacteriophage therapy. Since bacteriophages target bacteria and are strain-specific, every bacteriophage/bacterial host pair is unique. They are believed to cause no harm to humans. An additional advantage of the strain-specific nature of bacteriophages is that they do not disrupt the beneficial natural flora in the body. Bacteriophage therapy in the West is not a recognized medicine at this time, and no products are registered. Some clinicians are turning to bacteriophage therapy for the treatment of antibiotic-resistant infections. Lack of adverse effects makes bacteriophage therapy ideal for use. Funding research, media attention, and the increased publication of articles helped in a widespread understanding of its therapeutic potential. The first prerequisite for the use of bacteriophage therapy is simply the availability of bacteriophages for treatment, which is often complicated at this stage of bacteriophage production. This includes providing access to all biologically active bacteriophages against the bacterial isolate of the patient and meeting regulatory criteria of purity, traceability, and characterization. A monophage preparation, which is a single bacteriophage, or a phage cocktail, which consists of a number of combined bacteriophages against one or more bacterial species may be used. Accordingly, the antibiotic resistance crisis brought back bacteriophage therapy as a potential complementary or alternative treatment. Bacteriophages are promising cheap antibacterials.
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2

Putra, Ramendra Dirgantara, and Diana Lyrawati. "Interactions between Bacteriophages and Eukaryotic Cells." Scientifica 2020 (June 9, 2020): 1–8. http://dx.doi.org/10.1155/2020/3589316.

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As the name implies, bacteriophage is a bacterium-specific virus. It infects and kills the bacterial host. Bacteriophages have gained attention as alternative antimicrobial entities in the science community in the western world since the alarming rise of antibiotic resistance among microbes. Although generally considered as prokaryote-specific viruses, recent studies indicate that bacteriophages can interact with eukaryotic organisms, including humans. In the current review, these interactions are divided into two categories, i.e., indirect and direct interactions, with the involvement of bacteriophages, bacteria, and eukaryotes. We discuss bacteriophage-related diseases, transcytosis of bacteriophages, bacteriophage interactions with cancer cells, collaboration of bacteriophages and eukaryotes against bacterial infections, and horizontal gene transfer between bacteriophages and eukaryotes. Such interactions are crucial for understanding and developing bacteriophages as the therapeutic agents and pharmaceutical delivery systems. With the advancement and combination of in silico, in vitro, and in vivo approaches and clinical trials, bacteriophages definitely serve as useful repertoire for biologic target-based drug development to manage many complex diseases in the future.
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Maura, Damien, Matthieu Galtier, Chantal Le Bouguénec, and Laurent Debarbieux. "Virulent Bacteriophages Can Target O104:H4 Enteroaggregative Escherichia coli in the Mouse Intestine." Antimicrobial Agents and Chemotherapy 56, no. 12 (September 24, 2012): 6235–42. http://dx.doi.org/10.1128/aac.00602-12.

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ABSTRACTIn vivobacteriophage targeting of enteroaggregativeEscherichia coli(EAEC) was assessed using a mouse intestinal model of colonization with the O104:H4 55989Str strain and a cocktail of three virulent bacteriophages. The colonization model was shown to mimic asymptomatic intestinal carriage found in humans. The addition of the cocktail to drinking water for 24 h strongly decreased ileal and weakly decreased fecal 55989Str concentrations in a dose-dependent manner. These decreases in ileal and fecal bacterial concentrations were only transient, since 55989Str concentrations returned to their original levels 3 days later. These transient decreases were independent of the mouse microbiota, as similar results were obtained with axenic mice. We studied the infectivity of each bacteriophage in the ileal and fecal environments and found that 55989Str bacteria in the mouse ileum were permissive to all three bacteriophages, whereas those in the feces were permissive to only one bacteriophage. Our results provide the first demonstration that bacterial permissivity to infection with virulent bacteriophages is not uniform throughout the gut; this highlights the need for a detailed characterization of the interactions between bacteria and bacteriophagesin vivofor the further development of phage therapy targeting intestinal pathogens found in the gut of asymptomatic human carriers.
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Manrique, Pilar, Benjamin Bolduc, Seth T. Walk, John van der Oost, Willem M. de Vos, and Mark J. Young. "Healthy human gut phageome." Proceedings of the National Academy of Sciences 113, no. 37 (August 29, 2016): 10400–10405. http://dx.doi.org/10.1073/pnas.1601060113.

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The role of bacteriophages in influencing the structure and function of the healthy human gut microbiome is unknown. With few exceptions, previous studies have found a high level of heterogeneity in bacteriophages from healthy individuals. To better estimate and identify the shared phageome of humans, we analyzed a deep DNA sequence dataset of active bacteriophages and available metagenomic datasets of the gut bacteriophage community from healthy individuals. We found 23 shared bacteriophages in more than one-half of 64 healthy individuals from around the world. These shared bacteriophages were found in a significantly smaller percentage of individuals with gastrointestinal/irritable bowel disease. A network analysis identified 44 bacteriophage groups of which 9 (20%) were shared in more than one-half of all 64 individuals. These results provide strong evidence of a healthy gut phageome (HGP) in humans. The bacteriophage community in the human gut is a mixture of three classes: a set of core bacteriophages shared among more than one-half of all people, a common set of bacteriophages found in 20–50% of individuals, and a set of bacteriophages that are either rarely shared or unique to a person. We propose that the core and common bacteriophage communities are globally distributed and comprise the HGP, which plays an important role in maintaining gut microbiome structure/function and thereby contributes significantly to human health.
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SAKMANOĞLU, Aslı, та Hasan Hüseyin HADİMLİ. "Typing of ΦSP–3 lytic Salmonella bacteriophages obtained from various fecal sources". TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES 44, № 5 (27 жовтня 2020): 1047–54. http://dx.doi.org/10.3906/vet-2005-105.

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Although several reports are available on both ΦSP–1 and ΦSP–3 lytic Salmonella bacteriophages obtained from poultry, further research is required to study the effectiveness of ΦSP–3 type on serovars isolated from other sources. In the present study, we aimed to isolate bacteriophages from 8 serovars previously obtained from 869 fecal samples (calf, dairy cow, buffalo, and camel), genotype the bacteriophages, and detect the cross-lytic activities of the bacteriophages on Salmonella enterica subsp. enterica serovar Kentucky, S.Anatum, and S.Muenchen. A total of 16 bacteriophages were detected as ΦSP–3 type via PCR. The Hunter-Gaston Discriminatory Index of SDS-PAGE was calculated to be 0.825. Determination of multiplicity of infection (MOI) values were different for each bacteriophage according to the cross-lytic activity assessment. The MOI of the most effective S. Kentucky bacteriophage was 79.11 μg/mL for 2.5×104 cells, whereas that of the most ineffective S.Muenchen bacteriophage was 1.142 μg/μL for 2.5×104 cells. In conclusion, it was assumed that owing to the high and cross-lytic activity of the S. Kentucky bacteriophage, it has a larger host range, which differs in the lytic activities of each bacteriophage, despite being the same serovar, and that calf feces is the most important source for obtaining Salmonella bacteriophages.
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Ariyanti, Tati. "The Use of Bacteriophage for Detection and Biocontrol of Foodborne Pathogen." Indonesian Bulletin of Animal and Veterinary Sciences 28, no. 1 (March 3, 2018): 33. http://dx.doi.org/10.14334/wartazoa.v28i1.1791.

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Bacteriophages are viruses that have ability to attack bacterial cells in specific receptors, infect, multiply in bacterial cells and eventually lyse bacterial cells. This unique bacteriophage character is highly beneficial because it is harmless to mammalian cells and does not interfere with natural microbes. Bacteriophages are easy to obtain because they are widespread in the environment such as soil, water, animal, and farm waste or food. This paper describes the potential use of bacteriophages to detect pathogen and foodborne pathogen biocontrol. Bacteriophages are very potential to control the growth of pathogenic bacteria both in food industry and environment. Bacteriophages act as antibiotics, detection tool for pathogenic bacteria in the food chain, food biopreservative from pathogen bacteria contamination, and foodborne disease prevention. Although research on bacteriophage in Indonesia has not been widely reported, research on bacteriophage utilization is being carried on.
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7

Moon, Choi, Jeong, Sohn, Han, and Oh. "Research Progress of M13 Bacteriophage-Based Biosensors." Nanomaterials 9, no. 10 (October 11, 2019): 1448. http://dx.doi.org/10.3390/nano9101448.

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Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.
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TARAKANOV, R. I., A. N. IGNATOV, and F. S. DZHALILOV. "ISOLATION OF SPECIFIC BACTERIOPHAGES - PSEUDOMONAS SAVASTANOI PV. GLYCINEA - AND THEIR USE IN SOYBEAN BACTERIAL BLIGHT CONTROL." Izvestiâ Timirâzevskoj selʹskohozâjstvennoj akademii, no. 4 (2020): 43–53. http://dx.doi.org/10.26897/0021-342x-2020-4-43-53.

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Bacterial blight is one of most harmful diseases of legumes, reducing the profitability of soybean production in Russian Federation. Among a number of Pseudomonas isolates obtained from diseased seeds and plants of soybean, 4 strains were selected and confirmed as Pseudomonas savastanoipv. glycinea (Psg). Properties of the isolated bacteria were similar to type strain of Psg CFBP 2214 in plant virulence, LOPAT tests, and PCR analysis for coronafacate ligase gene, and partly – in the phage reaction profile. Four isolates of bacteriophages specific to Psg were obtained from soil samples taken from fields with soybean crops. Virulence testing for the bacteriophages showed that bacteriophage ϕG17 infected 4 of 5 tested Psg strains, and it was chosen for further experiments with bacterial blight control. The bacteriophague effect control conducted on soybent plants inoculated by Psg experiments confirmed that 2 treatments of plants by the bacteriophage significantly reduced the disease development. Biological effect of the bacteriophage application was 74.75%, which is very close to the pesticide Strekar in a concentration of 0.5%.
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Xu, Anqi. "Draft Of Bacteriophage Therapy Review." Highlights in Science, Engineering and Technology 74 (December 29, 2023): 1105–16. http://dx.doi.org/10.54097/hfwfxj54.

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Phage therapy, which uses bacterial viruses (bacteriophages) to treat bacterial infections. In recent years, the issue of antibiotic resistance in various bacteria has become prominent, and the effectiveness of antibiotic drugs has generally declined, which has re raised people's scrutiny of bacteriophage therapy. Traditionally, bacteriophage therapy relies on the use of natural bacteriophages to infect and dissolve bacteria at the site of infection. Current research on the use of bacteriophages and their lytic proteins to combat multidrug-resistant bacterial infections suggests that bacteriophage therapy may serve as a substitute or supplement to antibiotic therapy.
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Gorshenin, Aleksandr Vladimirovich. "Participation of microbiologists Z.V. Ermolyeva and L.M. Yakobson in a scientific discussion about the fate of the production of Soviet cholera bacteriophages in 1967." Samara Journal of Science 10, no. 4 (December 1, 2021): 201–7. http://dx.doi.org/10.17816/snv2021104211.

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Since the late 1920s in the USSR, along with many countries, there has been an interest in studying the phenomenon of bacteriophagy and its use in medicine. Bacteriophages are called bacterial viruses. Significant work on the study of bacteriophages and their use for medical purposes was carried out by Soviet microbiologists Zinaida Vissarionovna Ermolyeva and Lidiya Mikhailovna Yakobson. They paid especially great attention to the study of cholera bacteriophage, which during the Great Patriotic War helped prevent the cholera epidemic in frontline Stalingrad. In the 1940s due to the advent of the era of antibiotics with a wider range of applications, research interest in bacteriophages was waning. Nevertheless, in the prevention and treatment of a number of infectious diseases of bacterial origin, phage continued to be used in the following decades. In 1967, one of the countrys largest microbiologists sent an appeal to the Chief Sanitary Doctor of the USSR with a proposal to stop or reduce the production of cholera bacteriophage in the country. In this regard, a scientific discussion in which Z.V. Ermolyeva and L.M. Yakobson played an important role unfolded. Using the materials of the State Archive of the Russian Federation and the Russian State Archive of Economics, involving published scientific works on microbiology and medicine, an attempt is made to analyze this scientific discussion and establish its significance in the fate of the production of cholera bacteriophage in the USSR.
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Дисертації з теми "Bacteriophages"

1

Cramer, Todd James Lucas. "Genetic mosaicism between the bacteriophage [phi]80 and bacteriophage [lambda]." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1223514067.

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Maillard, Jean-Yves Maillard. "Bacteriophages and biocides." Thesis, Cardiff University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274316.

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Wells, Llyd Ewan. "Viral adaptations to life in the cold /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/11056.

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Dueñas, Marta. "Phage display and bacterial expression of antibody fragments." Lund : Dept. of Immunotechnology, Lund University, 1995. http://catalog.hathitrust.org/api/volumes/oclc/38164515.html.

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Cockburn, Joseph John Berry. "Structural studies on bacteriophages." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442832.

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Chan, Jacqueline. "Bacteriophages of marine Roseobacter." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/4512/.

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The oceans cover ca. 70% of the Earth’s surface and due to their depth encompass around 300 times the habitable volume of the terrestrial environment. The exact proportion of life on Earth that exists in the oceans is unknown as many ocean species remain undiscovered; in particular this holds true for the viruses that infect marine bacterioplankton. It is currently thought that viruses that infect bacteria, bacteriophages or phages, can numerically exceed their hosts by a factor of ten, however, this abundant and diverse group of organisms is still poorly understood. This is especially true of phages that infect members of the Roseobacter clade. Globally, members of the Roseobacter lineage can comprise up to a quarter of the marine microbial community and often dominate the alga-associated bacterial community. In this study phages capable of infecting species of Roseobacter were isolated and characterised. Two Roseovarius-specific phages, RLP1 and RPP1, were isolated from UK coastal waters; morphological and sequence data identified them as belonging to the N4-like genus of Podoviridae. Comparative genomic analysis of both Roseovarius phages to other N4-like phages such as Escherichia coli phage N4 and Sulfitobacter sp. EE-36 phage EE36Φ1, revealed a number of conserved core genes involved in DNA metabolism, transcription control and virion structure. Comparison of N4-like Roseobacter phages (RLP1, RPP1, EE36Φ1 and Ruegeria pomeroyi DSS-3 phage DSS3Φ2) also revealed a number of peripheral genes which are likely to interact directly with host proteins/machinery specific to the Roseobacter group. Unusually, both RLP1 and RPP1 appeared to only infect host cells when in semi-solid agar matrix, but not in liquid culture. Comparison of the outer surface of agar-embedded and planktonic cells revealed different outer-membrane protein and lipopolysaccharide expression profiles. This suggests that some Roseobacter species (spp.) change components of their bacterial cell surface according to their physiological state: agar-embedded/sessile or planktonic and RLP1 and RPP1 exploit this by binding to (a) receptor(s) only expressed during sessile conditions. A number of prophage-like elements were also induced from three Roseobacter spp. by exposure of growing cultures to the DNA-damaging chemical Mitomycin C. These were identified by electron microscopy as belonging to the Siphoviridae family. The results of this project suggest that within the marine environment there remain many uncharacterised phages with peculiar biochemical properties and a wealth of genomic information.
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Xu, Zinan. "Isolation, characterisation and application of bacteriophages in aquaculture." Thesis, University of Stirling, 2016. http://hdl.handle.net/1893/23740.

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The increasing incidence of infections due to antibiotic resistant bacteria has led to renewed interest in bacteriophages (= phages) and phage therapy. Although phage therapy has been applied to control bacterial diseases in plants, poultry, livestock and humans, its application in aquaculture is still relatively limited. The emergence of phage-resistant bacterial mutants has been considered to be one of the major limitations of phage therapy. This study aimed to (i) isolate and characterise phages; (ii) select phages and their bacterial hosts to set up in vivo phage therapy models with aquaculture animals, and estimate the efficiency of phage therapy; (iii) investigate the generation and characteristics of phage-resistant mutants, and thus estimate the consequence of applying phage therapy when phage-resistant mutants emerge; and (iv) discuss the prospects for application of phages in aquaculture. Two Vibrio isolates and their phages were isolated from a Scottish marine fish farm. Based on the results of conventional phenotype testing and 16S rRNA gene sequencing analysis, the two vibrios, V9 and V13, were identified as Vibrio splendidus and Vibrio cyclitrophicus, respectively. The bacterial characteristics including morphology, temperature and salinity range of growth, production of extracellular enzymes, and the possession of virulence genes were examined. According to the morphological characteristics observed using transmission electron microscopy by negative staining, phage PVS9 of V. splendidus V9 was identified as a myophage, while phage PVC13 of V. cyclitrophicus V13 was identified as a siphophage. The phages could only lyse one bacterial host strain and their genomic DNA was double stranded with a size of ~46 kb. The two Vibrio isolates were found to be non- or of low virulence to rainbow trout, goldsinny wrasse and Artemia in pathogenicity experiments. Thus an in vivo phage therapy model could not be set up using these Vibrio isolates and their phages. Two phages pAS-3 and pAS-6 were isolated using the Aeromonas salmonicida subsp. salmonicida Hooke strain as the host. Phages pAS-3 and pAS-6 had a similar genome size of ~50 kb, and the same relatively narrow host range within A. salmonicida subsp. salmonicida strains. The siphophage pAS-3 formed clear plaques and inhibited A. salmonicida Hooke growth in vitro completely for at least 18 hours when using MOI = 1,000, whereas the podophage pAS-6 formed turbid plaques and weakly inhibited Hooke growth. Rainbow trout exposed by intraperitoneal injection with 0.1 mL of the raw phage preparations at a concentration of 108 PUF mL-1 showed no adverse effects over 14 days. In the phage therapy trial, fish were firstly injected with 1 x 102 CFU fish-1 of A. salmonicida Hooke, then immediately injected with phage preparations of pAS-3 and pAS-6, respectively, using MOI = 10,000. Compared with the control group (which did not receive phage treatment), phage treated groups showed a delay in the time to death, and lower mortalities. However, the mortalities and time to death between phage treated and non-treated groups were not significantly different. Phage-resistant mutants of pathogenic A. salmonicida strain Hooke were induced by repeatedly challenging with phage pAS-3. One of the mutants, termed HM, was chosen to compare the characteristics with the parental wild-type strain Hooke. Test results including the formation of ‘smooth’ colonies on TSA, autoagglutination negative, the formation of creamy colonies on Coomassie Brilliant Blue agar, and the degradation of a thick/furry layered structure on the cell surface indicated a deficiency of the A-layer in the phage-resistant mutant HM. Therefore, it was deduced that the A-layer either directly acted as the receptor of A. salmonicida phage pAS-3, or was affected indirectly by the change of an unknown phage receptor. The greater wax moth larvae model was used to compare the virulence of the phage-resistant mutant HM and the parental wild-type strain Hooke, as it is an ethically acceptable animal model, which has the advantages of being low cost and convenient for injection, and is also a recognised alternative model for bacterial pathogens of fish. The results showed that virulence of the phage-resistant mutant HM did not decline in the greater wax moth larvae model compared with that of the parental wild-type strain Hooke. In conclusion, different approaches were used to isolate and characterise phages from different aquaculture environments for potential use in phage therapy. A rainbow trout model was set up using pathogenic A. salmonicida strain Hooke and two A. salmonicida phages pAS-3 and pAS-6. The use of phage treatment led to lower cumulative mortalities and delay to the time of death, although the differences between the groups were not significant, futher work is required to determine if these phages have potential in phage therapy. The consequence of applying phage therapy when phage-resistant mutants emerge was estimated based on their characteristics and virulence, and no decline in virulence of the phage-resistant mutant from this study indicates the importance of fully testing the virulence of phage-resistant mutants before carrying out large scale field trials of phage therapy. It appears feasible to use phage therapy as an alternative approach to control bacterial infections in aquaculture, but further studies are required to focus on improving effectiveness, and also to overcome the concrete limitations and hurdles in application and commercialisation. Moreover, a broader range of applications of phages in aquaculture should be explored.
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Sandegren, Linus. "Group I Introns and Homing Endonucleases in T-even-like Bacteriophages." Doctoral thesis, Stockholm : Institutionen för molekylärbiologi och funktionsgenomik, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-211.

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Varlakova, A., Нiна Володимирiвна Мальована, Нина Владимировна Малеванная, and Nina Volodymyrivna Malovana. "Bacteriophages as alternatives to antibiotics." Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/77972.

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The history of the discovery of bacteriophages began almost a century ago. In spite of the appearance of antibiotics, bacteriophages are still extremely promising. Bacterial infections are an urgent public health problem, due to the increasing of antibiotic resistance and negative health consequences. Thus, phages are currently considered as an alternative treatment, which are going to replace antibiotics.
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Lymer, David. "Significance and Diversity of Lake Bacteriophages." Doctoral thesis, Uppsala : Uppsala universitet, Universitetsbiblioteket, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9499.

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Книги з теми "Bacteriophages"

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Clokie, Martha R. J., Andrew Kropinski, and Rob Lavigne, eds. Bacteriophages. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8940-9.

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Harper, David R., Stephen T. Abedon, Benjamin H. Burrowes, and Malcolm L. McConville, eds. Bacteriophages. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-40598-8.

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Clokie, Martha R. J., and Andrew M. Kropinski, eds. Bacteriophages. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-565-1.

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Clokie, Martha R. J., and Andrew M. Kropinski, eds. Bacteriophages. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-164-6.

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Clokie, Martha R. J., Andrew M. Kropinski, and Rob Lavigne, eds. Bacteriophages. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7343-9.

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Kurtböke, Ipek. Bacteriophages. Rijeka, Croatia: InTech, 2012.

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7

Tumban, Ebenezer, ed. Bacteriophages. New York, NY: Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3549-0.

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Calendar, Richard, ed. The Bacteriophages. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5424-6.

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Calendar, Richard, ed. The Bacteriophages. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5490-1.

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Richard, Calendar, ed. The Bacteriophages. New York: Plenum Press, 1988.

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Частини книг з теми "Bacteriophages"

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Klaenhammer, T. R., and G. F. Fitzgerald. "Bacteriophages and bacteriophage resistance." In Genetics and Biotechnology of Lactic Acid Bacteria, 106–68. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-1340-3_3.

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Sanz-Gaitero, Marta, Mateo Seoane-Blanco, and Mark J. van Raaij. "Structure and Function of Bacteriophages." In Bacteriophages, 1–73. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-40598-8_1-1.

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Harper, David R. "Bacteriophage as Biocontrol Agents." In Bacteriophages, 1–16. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-40598-8_10-1.

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Summers, William C. "The Discovery of Bacteriophages and the Historical Context." In Bacteriophages, 1–15. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-40598-8_11-1.

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Chanishvili, Nina, and Zemphira Alavidze. "Early Therapeutic and Prophylactic Uses of Bacteriophages." In Bacteriophages, 1–30. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-40598-8_12-1.

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van Charante, Frits, Dominique Holtappels, Bob Blasdel, and Ben Burrowes. "Isolation of Bacteriophages." In Bacteriophages, 1–32. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-40598-8_14-1.

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Brown, Nathan, and Chris Cox. "Bacteriophage Use in Molecular Biology and Biotechnology." In Bacteriophages, 1–42. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-40598-8_15-1.

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Abedon, Stephen T. "Detection of Bacteriophages: Phage Plaques." In Bacteriophages, 1–32. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-40598-8_16-1.

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Abedon, Stephen T., and Tena I. Katsaounis. "Detection of Bacteriophages: Statistical Aspects of Plaque Assay." In Bacteriophages, 1–23. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-40598-8_17-1.

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Belnap, David M. "Detection of Bacteriophages: Electron Microscopy and Visualisation." In Bacteriophages, 1–61. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-40598-8_18-1.

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Тези доповідей конференцій з теми "Bacteriophages"

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Shydlovska, Olga, and Yuliia Khmelnytska. "L. lactis Bacteriophages and Methods of Their Elimination from Dairy Products." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.ii.23.

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Dairy products are important in human diet and nutrition. That is why dairy production is critical not only economically, but also socially and medically. In recent decades, dairy production has had problems with disturbances in fermentation processes caused by bacteriophage contamination. It is important to note that every year there are new reports about newly discovered bacteriophages that disrupt fermentation processes in the production of kefir, yogurt, and various types of cheese. Lactococcus lactis strains are of particular importance in dairy technology, as they are used for the production of various yogurts and cheeses. The study of the spectrum of bacteriophages infecting this strain can help to monitor the evolutionary changes of viruses and the horizontal transfer of genes. In this paper, an analysis of phages infecting L. lactis was carried out. Most bacteriophages belong to the Siphoviridae and Podoviridae families. Moreover, the authors analyzed approaches that can be used to reduce bacteriophage contamination in the production of dairy products. It has been shown that the use of disinfectants, such as ethanol on sodium hypochlorite, can reduce the titer of bacteriophages and protect products from the development of viral infection. It is also possible to use membrane filtration with UV irradiation. Moreover, all these approaches can be combined to achieve the most effective result.
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Orynbayev, A. T., K. A. Miroshnikov, A. N. Ignatov, and F. S. Dzhalilov. "Evaluation of effectiveness of bacteriophage agent for cabbage black rot control." In Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-113.

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Twenty-one isolates of bacteriophages specific to eleven target strains of Xanthomonas campestris pv. campestris were isolated from soil samples collected under black rot-infected cabbage plants. After the analysis of phagotyping for seventy-three phytopathogen strains against newly isolated isolates and four collection strains of bacteriophages, it was proposed to construct a phage cocktail including 6 isolates In vitro screening of protective from ultraviolet radiation substances under the UV-B range showed that skim milk (0.75%), Riboflavin (0.5%) and ascorbic acid (0.1%) showed the highest effect for bacteriophages. Under the conditions of a film greenhouse, the best protective effect from solar UV radiation on the 8th day after spraying cabbage was shown by the option with the addition of skimmed milk (0.75%) and Riboflavin (0.5%). According to our data, these substances can provide a long-term photoprotective effect of the bacteriophage preparation..
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Besarab, N. V., A. K. Golomidova, E. E. Kulikov, A. V. Letarov, A. L. Lagonenko, and A. N. Evtushenkov. "Characterization of Erwinia amylovora bacteriophages isolated in Belarus." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.042.

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Erwinia amylovora bacteriophages from the Myoviridae and Podoviridae families were isolated in Belarus. The E. amylovora growth rate was 1.6-7.8 times decreased in the presence of investigated bacteriophages.
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Самойлова, Анна. "Бактериофаги Pseudomonas syringae pv. syringae перспективные в подавлении развития бактериального рака плодовых". У VIIth International Scientific Conference “Genetics, Physiology and Plant Breeding”. Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, 2021. http://dx.doi.org/10.53040/gppb7.2021.88.

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Five Pseudomonas syringae pv. syringae bacteriophages were isolated from the quince, apple and pear. After a detailed study, the isolated bacteriophages could be used for biocontrol of the bacterial canker patho-gen. One of the isolated phages was active against the causative agents of bacterial canker and fire blight.
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Jdeed, G., V. Morozova, T. Ushakova, Yu Kozlova, A. Tikunov, A. Bardasheva, and N. Tikunova. "STM171, A STENOTROPHOMONAS BACTERIOPHAGE WITH EFFECTS ON ANTIBIOTIC ACTIVITY AGAINST BIOFILM FORMATION." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-225.

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Stenotrophomonas maltophilia is associated with high mortality rates for immunocompromised patients. Bacteriophages appear as a promising therapeutic tool to be used as a replacement or in addition to antibiotics, currently around 63 S. maltophilia bacteriophages are known, and their effects when used with antibiotics and against biofilm are poorly studied.
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Kulikov, V. V., D. N. Shcherbakov, and N. V. Volkova. "DEVELOPMENT OF RECOMBINANT BACTERIOPHAGES FOR THE PRODUCTION OF REINFORCED RNA." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-94.

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We have developed a system for the construction of recombinant bacteriophages MS2, this technology makes it possible to obtain bacteriophages with specified RNA sequences, which allows us to produce stably stored, RNAse-resistant RNA for further use in highly sensitive analytical methods, as control samples, or in other tasks requiring protected RNA.
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Ferreira, A. A., R. C. S. Mendonça, H. M. Hungaro, M. M. Carvalho, and J. A. M. Pereira. "Bacteriophages actions on Salmonella Enteritidis biofilm." In Proceedings of the International Conference on Antimicrobial Research (ICAR2010). WORLD SCIENTIFIC, 2011. http://dx.doi.org/10.1142/9789814354868_0026.

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Acharya, Dipti, Alok Bhardwaj, and Kundan Kumar Chaubey. "Bacteriophages and lysins: Novel potential antimicrobials." In RECENT ADVANCES IN SCIENCES, ENGINEERING, INFORMATION TECHNOLOGY & MANAGEMENT. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0154209.

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Działak, Paweł, Andrzej Borkowski, Artur Błachowski, and Mirosław Słowakiewicz. "Bacteriophages affect precipitation of iron minerals." In Goldschmidt2023. France: European Association of Geochemistry, 2023. http://dx.doi.org/10.7185/gold2023.17630.

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Dichelmüller, H., та W. Stephan. "ROUTINE MONITORING OF THE β-PROPIOLACTONE/UV STERILIZATION PROCEDURE USING BACTERIOPHAGES". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644058.

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Cold sterilization of plasma or plasma derivatives such as the serum preserve Biseko® and coagulation factor concentrates by β-Propiolactone (β-PL)/UV has been demonstrated in various studies to be effective in inactivation of Hepatitis viruses and HIV. The methods used in these studies are not applicable in routine monitoring of sterilization processes, as chimpanzees must be involved in the titration of Hepatitis B or NANB viruses.For routine monitoring of the sterilization efficacy we therefore developed a test system using four types of bacteriophages: Øx 174, Øe, Kappa and f2. Using these bacteriophages in 88 single tests, sterilization efficacy was regularly monitored during the period fran 1981 to 1986. For these tests samples were drawn from pooled human plasma, spiked with bacteriophages and subjected to the cold sterilization procedure under identical conditions and apparative equipenent, but strictly separated fran the production process. By treatment with β-Propiolactone and UV all bacteriophages were inactivated by more than 6.7 log10, independent from size or genom structure. This inactivation is in the range of inactivation of Hepatitis B virus by β-PL/UV as a relevant pathogenic virus. During this six year period of monitoring no significant alternations in sterilization efficacy were observed, indicating a constantly safe inactivation rate for numerous production lots and for many years of production.
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Звіти організацій з теми "Bacteriophages"

1

Ireland, Tom. Scaling Phage Therapy. Asimov Press, February 2024. http://dx.doi.org/10.62211/82rs-14tp.

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Nasser, Abidelfatah, Charles Gerba, Badri Fattal, Tian-Chyi Yeh, and Uri Mingelgrin. Biocolloids Transport to Groundwater. United States Department of Agriculture, December 1997. http://dx.doi.org/10.32747/1997.7695834.bard.

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The first phase of the study was designed to determine the adsorption rate of viruses and microspheres to sandy and loamy soils and determine the adsorption efficiency of various viruses to soil. The adsorption of viruses to sandy and loamy soils has been found virus type dependent. The poorest adsorption was observed for MS2 bacteriophage while the greatest adsorption was observed for PRD-1. Adsorption sites on the soil material were not found as limiting factors for adsorption of viruses on soil material. The effect of water quality on adsorption has been found as virus type dependent. The adsorption process of microspheres to soil material has been found to be similar to that of viruses and occurs within a very short period of time. Carboxylated (negatively charged) microspheres seems to adsorb more efficiently than plain microspheres to soil material. At low temperatures (10oC), and under saturated conditions no virus die-off was observed, therefore under these conditions virus can survive for long period of time. At 23oC, and saturated conditions, the greatest die-off was observed for MS2 bacteriophage, whereas, negligible die-off was for PRD-1 bacteriophage and hepatitis A virus. Considering the survival results MS2 bacteriophages is not suitable as indicator for pathogenic viruses persistence in soil material. Furthermore, temperature, is more important than any other factor for the inactivation of viruses.
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Torok, Tamas, and Romy Chakraborty. Application of Bacteriophages of Sulfate-Reducing Bacteria in Science and Technology. Office of Scientific and Technical Information (OSTI), May 2017. http://dx.doi.org/10.2172/1426501.

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Garcia, Emilio, and Alexander Sulakvelidze. Investigation of Polymetric Biofilms Formed by Dangerous Pathogens, and the Prevention of Their Formation by Disinfectants and Bacteriophages Final Report CRADA No. TC02145.0. Office of Scientific and Technical Information (OSTI), March 2018. http://dx.doi.org/10.2172/1432979.

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Garcia, Emilio. Investigation of Polymetric Biofilms Formed by Dangerous Pathogens, and the Prevention of Their Formation by Disinfectants and Bacteriophages Final Report CRADA No. TC02145.0. Office of Scientific and Technical Information (OSTI), April 2013. http://dx.doi.org/10.2172/1084462.

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Gindt, Alexander. Bacteriophage Therapy: A Fight Against Antimicrobial Resistance. Ames (Iowa): Iowa State University, May 2023. http://dx.doi.org/10.31274/cc-20240624-277.

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Schnider, Shirley. The biological properties of Pseudomonas aeruginosa bacteriophage 7V. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.771.

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Wick, Charles H., and Patrick E. McCubbin. Removing Complex Growth Media from MS2 Bacteriophage Cultures. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada368537.

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Wick, Charles H., and Patrick E. McCubbin. Filtration Characteristics of MS2 Bacteriophage Using Various Molecular Weight Filters. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada368535.

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Benson, Deanne. A study of RNA bacteriophage 7s infection of Pseudomonas aeruginosa. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.2139.

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