Добірка наукової літератури з теми "B cells"
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Статті в журналах з теми "B cells":
Tangye, Stuart G., and Kim L. Good. "Human IgM+CD27+B Cells: Memory B Cells or “Memory” B Cells?" Journal of Immunology 179, no. 1 (June 19, 2007): 13–19. http://dx.doi.org/10.4049/jimmunol.179.1.13.
MacConmara, Malcolm, and James A. Lederer. "B cells." Critical Care Medicine 33, Suppl (December 2005): S514—S516. http://dx.doi.org/10.1097/01.ccm.0000190616.15952.4b.
Dörner, Thomas, and Peter E. Lipsky. "B cells." Current Opinion in Rheumatology 26, no. 2 (March 2014): 228–36. http://dx.doi.org/10.1097/bor.0000000000000000.
Ollila, Juha, and Mauno Vihinen. "B cells." International Journal of Biochemistry & Cell Biology 37, no. 3 (March 2005): 518–23. http://dx.doi.org/10.1016/j.biocel.2004.09.007.
Haas, Karen M. "Noncanonical B Cells: Characteristics of Uncharacteristic B Cells." Journal of Immunology 211, no. 9 (November 1, 2023): 1257–65. http://dx.doi.org/10.4049/jimmunol.2200944.
Hananeh, W., R. Al Rukibat, and M. Daradka. "Primary splenic diffuse large B-cell lymphoma with multinucleated giant cells in a horse." Veterinární Medicína 66, No. 2 (February 2, 2021): 76–79. http://dx.doi.org/10.17221/61/2020-vetmed.
ANDREW, ANN. "DEVELOPMENTAL RELATIONSHIPS OF NEUROENDOCRINE CELLS ." Biomedical Research 6, no. 4 (1985): 191–96. http://dx.doi.org/10.2220/biomedres.6.191.
Yeo, Seung Geun, Joong Saeng Cho, Dong Choon Park, and Thomas L. Rothstein. "B-1 Cells Differ from Conventional B (B-2) Cells: Difference in Proliferation." Immune Network 4, no. 3 (2004): 155. http://dx.doi.org/10.4110/in.2004.4.3.155.
YANABA, Koichi. "Regulatory B cells." Japanese Journal of Clinical Immunology 32, no. 3 (2009): 135–41. http://dx.doi.org/10.2177/jsci.32.135.
Cory, Suzanne. "Masterminding B Cells." Journal of Immunology 195, no. 3 (July 17, 2015): 763–65. http://dx.doi.org/10.4049/jimmunol.1501277.
Дисертації з теми "B cells":
Carnathan, Diane Gail Vilen Barbara J. "Dendritic cell regulation of B cells." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1200.
Title from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Master of Science in the Department of Microbiology and Immunology, School of Medicine." Discipline: Microbiology and Immunology; Department/School: Medicine.
Crawford, A. "How B cells influence T cell responses." Thesis, University of Edinburgh, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.645118.
Memon, Azka. "The function of CD180 toll like receptor(TLR) on control B cells and B cell chronic lymphocytic leukaemia (B-CLL) cells." Thesis, University of Westminster, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507859.
Snell, Daniel C. "Cell-surface molecules of developing chicken B cells." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326977.
Mahajan, Simmi. "Development of T cell help for B cells." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/12548.
Ke, Chyan Ying. "Nanoscale antigen organization regulates binding to specific B-cells and B-cell activation." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/97825.
Cataloged from PDF version of thesis. "February 2015."
Includes bibliographical references.
The successes of vaccines in modern medicine diminished the morbidity and mortality of many pathogenic infections. Yet, difficulties remain in improving the immunogenicity of modern subunit vaccines. In addition, isolation of antigen-specific memory B cells that would elucidate the long-term efficacy of vaccines beyond using antibody titers as surrogates has been challenging due to the lack of specific and sensitive detection reagent. We sought to improve the binding and activation of B cells by presenting antigens in a multivalent manner on the surface of liposomes. Motivated by structural requirements originally defined for haptens triggering T-cell-independent stimulation of B cells, we investigated how the mode of antigen presentation, antigen density, particle size, and lipid mobility influence B cell receptor (BCR) crosslinking by multivalent antigen-bearing liposomes, and found that BCR binding is not only a function of antigen density, but also the spacing of antigens on a nanoscale- even for highly multivalent particles. We demonstrated high sensitivity in detecting antigen-specific B cells in vitro, as well as in detecting antigenspecific memory B cells in immunized mice. We first present a novel method of nanoclustering biotinylated antigens conjugated on liposomes with streptavidin, and examine the effect of nanoclustering on BCR binding and B cell response. The mere addition of streptavidin to otherwise 'unclustered' antigens displayed on liposomes increased binding of these particles to antigen-specific B-cells twofold and upregulated activation markers six fold while demonstrating a dose-sparing effect. A three-fold increase in the expression of the activation marker CD86 over soluble tetrameric antigen indicated that surface presentation on liposomes enhances the recognition of nanoclustered antigen by B cells. We then examined how nanoscale organization of antigens influences B cell responses for application to subunit vaccines, using well-defined peptide antigen multimers. Our experiments revealed that B cells bind to and respond to antigens in a valency-dependent manner, with a end-to-end distance spacing of approximately 11.8 nm required between antigens. In vivo immunization experiments demonstrated that higher antigen valencies elicited increased antigen titers and antibody avidity, as well as a responsive memory B cell population that proliferated more rapidly during secondary challenge, indicating a promising strategy for designing subunit vaccines of high immunogenicity. In conclusion, we demonstrated that multivalent presentation of antigens on liposomes enhanced BCR crosslinking and subsequent B cell activation. In addition, we showed that by systematically optimizing the structural requirements of nanoscale antigen organization, we are able to elicit robust B cell responses to low-affinity antigens.
by Chyan Ying Ke.
Ph. D.
Jo, Tomoyasu. "LUBAC accelerates B-cell lymphomagenesis by conferring B cells resistance to genotoxic stress." Kyoto University, 2020. http://hdl.handle.net/2433/259010.
Kobert, Antonia. "CNS-resident cells support MS-relevant B-cell responses." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114274.
L'appauvrissement des cellules B en périphérie est un traitement effectif chez les patients atteints de la SP et ce type cellulaire semblerait être un important médiateur lors des rechutes associés à la maladie. Toutefois, ils peuvent aussi induire les réactions inflammatoires compartimentées dans le SNC qui semblent être à la base des stades chroniques-progressifs de la maladie. La persistance des plasmocytes dans le SNC et les agrégations cellulaires riche en cellules B, cellules T et en cellules ressemblant aux CDFs dans les méninges des patients suggèrent que le SNC inflammé lors de la SP fonctionne comme étant un environnement favorisant les cellules B. Les facteurs qui contribuent à cet environnement permissif sont restés faiblement compris.Nous démontrons que les cellules gliales et leurs produits solubles peuvent supporter la survie des cellules B ainsi que les fonctions pertinentes à la SP, incluant l'expression des molécules co-stimulatrices et l'activation des cellules T, la sécrétion des cytokines effectrices et la production des immunoglobulines. Les produits solubles gliaux sont anormalement élevés dans la FCS des patients, nous avons donc supposé que le FCS de la SP pourrait supporter la survie des cellules B. Nous démontrons que le FCS seul, en isolement de l'environnement cellulaire complexe du SNC de la SP inflammé, n'est pas capable de supporter la survie des cellules B in-vitro. Nous démontrons aussi que les produits solubles sécrétés par les CEs de la BHE et des méninges peuvent augmenter ou modérer la survie des cellules B et peuvent aussi augmenter l'expression de la molécule co-stimulatrice CD86.Nos observations suggèrent que les cellules gliales et les CEs résidants dans le SNC ainsi que leur produits solubles peuvent significativement contribuer à un environnement permissif pour les cellules B et peuvent aussi supporter leurs fonctions effectrices pertinentes à la SP dans le SNC inflammé de patients.
Bansal, Raj Rani. "B cell help provided by human γδ T cells". Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/36649/.
Crawford, Alison. "Role of B cells in influencing T cell responses." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/13483.
Книги з теми "B cells":
Vitale, Gaetano, and Francesca Mion, eds. Regulatory B Cells. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1161-5.
Mion, Francesca, and Silvia Tonon, eds. Regulatory B Cells. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1237-8.
J, Paige C., and Gisler R. H, eds. Differentiation of B lymphocytes. Berlin: Springer-Verlag, 1987.
Petrov, R. V. Suppressor B lymphocytes. Chur, Switzerland: Harwood Academic Publishers, 1988.
1942-, Honjo T., Alt Frederick W, and Neuberger M. S, eds. Molecular biology of B cells. Amsterdam: Elsevier, 2004.
1948-, Cambier John C., ed. B-lymphocyte differentiation. Boca Raton, Fla: CRC Press, 1986.
Vitale, Gaetano, and Francesca Mion. Regulatory B cells: Methods and protocols. New York: Humana Press, 2014.
Klaus, G. G. B. B lymphocytes. Oxford: IRL Press at Oxford University Press, 1990.
1952-, Zouali Moncef, ed. Human B-cell superantigens. Austin: Landes, 1996.
A, Herzenberg Leonore, Haughton Geoffrey, and Rajewsky K. 1936-, eds. CD5 B cells in development and disease. New York, N.Y: New York Academy of Sciences, 1992.
Частини книг з теми "B cells":
Mehlhorn, Heinz. "B Cells." In Encyclopedia of Parasitology, 251. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_370.
Mehlhorn, Heinz. "B Cells." In Encyclopedia of Parasitology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-642-27769-6_370-2.
Srinivasan, Ramachandran. "B Cells." In Encyclopedia of Systems Biology, 67–68. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_960.
Fujimoto, Manabu. "B Cells." In Immunology of the Skin, 113–30. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55855-2_7.
Sharma, Sanjeev Kumar. "B Cells." In Basics of Hematopoietic Stem Cell Transplant, 87–120. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-5802-1_10.
Ward, Siobhan, Zeynep Celebi Sözener, and Mübeccel Akdis. "B Cells and Plasma Cells." In Chronic Rhinosinusitis, 47–55. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-0784-4_7.
Wang, Luman, Ying Fu, and Yiwei Chu. "Regulatory B Cells." In Advances in Experimental Medicine and Biology, 87–103. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3532-1_8.
Troilo, Arianna, Nagaja Capitani, Laura Patrussi, Cosima T. Baldari, and Mario Milco D’Elios. "Mucosal B Cells." In Humoral Primary Immunodeficiencies, 21–34. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91785-6_2.
Mauri, Claudia, and Paul Blair. "Regulatory B Cells." In Encyclopedia of Medical Immunology, 949–55. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-0-387-84828-0_551.
Jacobs, Jonathan P. "Innate B Cells." In Molecular Life Sciences, 1–6. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_121-2.
Тези доповідей конференцій з теми "B cells":
Lommatzsch, M., M. Dost, N. Jaishankar, M. Weise, P. Stoll, J. C. Virchow, and K. Bratke. "Dupilumab treatment increases transitional B-cells (regulatory B-cells) in severe asthma." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.3281.
"02 Targeting B cells and plasma cells." In 8th ANNUAL MEETING OF THE LUPUS ACADEMY, Warsaw, Poland, September 6–8, 2019. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-la.14.
Craft, Joe. "AI-10 Tfh cells and B-cell selection." In LUPUS 21ST CENTURY 2018 CONFERENCE, Abstracts of the Fourth Biannual Scientific Meeting of the North and South American and Caribbean Lupus Community, Armonk, New York, USA, September 13 – 15, 2018. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-lsm.10.
Davidson, Anne. "20 Cells involved in SLE: beyond B cells." In 11th Annual Meeting of the Lupus Academy, Hybrid meeting held 8–10th April 2022 in Florence, Italy. Lupus Foundation of America, 2022. http://dx.doi.org/10.1136/lupus-2022-la.20.
Sahin, Osman, Ali Kosar, and Murat Kaya Yapici. "Modeling the Dielectrophoretic Separation of Red Blood Cells (RBCs) from B-Lymphocytes (B-Cells)." In 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2021. http://dx.doi.org/10.1109/embc46164.2021.9631013.
Sauer, Karsten, Claire Conche, Hyun-Yong Jin, Kelly Bethel, Stephanie Rigaud, Luise Westernberg, Sabine Siegemund, and Changchun Xiao. "Abstract LB-020: IP3 3-kinase B suppresses B-cell lymphoma by antagonizing PI3K/mTOR in B cells." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-020.
Bao, Jiantong, Sandra Stanojevic, Jens Greve, J. Patrick Schuler, Marie-Nicole Theodoraki, Simon Laban, K. Thomas Hoffmann, and Cornelia Brunner. "Human germinal center B cells and marginal zone B cells associate with clinical features in head and neck squamous cell carcinoma." In 94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1767147.
Costa, Leonardo, Jürgen Haas, Henriette Rudolph, Saskia Libicher, Sven Jarius, Tobias Tenenbaum, Horst Schroten, and Brigitte Brigitte Wildemann. "The Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B Cell Subset in Multiple Sclerosis." In Building Bridges in Medical Science 2021. Cambridge Medicine Journal, 2021. http://dx.doi.org/10.7244/cmj.2021.03.001.2.
Graver, J., M. Sandovici, E. Haacke, A. Boots, and E. Brouwer. "THU0026 Organised b cells and plasma cells in the aorta of giant cell arteritis patients." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.3243.
Xu, L., F. Hu, X. Liu, L. Zhu, L. Ren, H. Liu, H. Zhu, and Y. Su. "AB0102 Impairment of granzyme b-producing regulatory b cells exacerbated rheumatoid arthritis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2269.
Звіти організацій з теми "B cells":
Moran, Nava, Richard Crain, and Wolf-Dieter Reiter. Regulation by Light of Plant Potassium Uptake through K Channels: Biochemical, Physiological and Biophysical Study. United States Department of Agriculture, September 1995. http://dx.doi.org/10.32747/1995.7571356.bard.
Author, Not Given. Appendix B: GPRA07 Hydrogen, Fuel Cells, and Infrastructure Technologies (HFCIT) program documentation. Office of Scientific and Technical Information (OSTI), January 2009. http://dx.doi.org/10.2172/1216620.
Menlove, Howard Olsen, and Daniela Henzlova. High-Dose Neutron Detector Development Using 10B Coated Cells. Office of Scientific and Technical Information (OSTI), November 2016. http://dx.doi.org/10.2172/1331305.
Catalano, A., R. Ayra, M. Bennett, C. Dickson, B. Fieselmann, B. Goldstein, J. Morris, et al. Task B: Research on stable high-efficiency, large area, amorphous silicon-based solar cells. Office of Scientific and Technical Information (OSTI), October 1989. http://dx.doi.org/10.2172/5206295.
Banai, Menachem, and Gary Splitter. Molecular Characterization and Function of Brucella Immunodominant Proteins. United States Department of Agriculture, July 1993. http://dx.doi.org/10.32747/1993.7568100.bard.
Author, Not Given. Appendix B: Hydrogen, Fuel Cells, and Infrastructure Technologies Program inputs for FY 2008 benefits estimates. Office of Scientific and Technical Information (OSTI), January 2009. http://dx.doi.org/10.2172/1216637.
Patz, Jr, and Edward F. Antibodies Expressed by Intratumoral B Cells as the Basis for a Diagnostic Test for Lung Cancer. Fort Belvoir, VA: Defense Technical Information Center, June 2015. http://dx.doi.org/10.21236/ada621368.
Cooper, Carlton R., and Kenneth Pienta. Induced Expression of Androgen Receptor in Androgen Independent Prostate Cancer Cells Using an I kappa B alpha Super Repressor"". Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada410579.
Yen, Timothy J. Suppression of Chromosome Instability (CIN) to Enhance Chemosensitivity of Ovarian Tumor Cells by Modulating the Aurora B Pathway at Kinetochores. Fort Belvoir, VA: Defense Technical Information Center, February 2013. http://dx.doi.org/10.21236/ada585095.
Zhu, Jun, Yuqin Song, and Zhitao Ying. Efficacy and safety of anti-CD19 chimeric antigen receptor-T cells immunotherapy in patients with relapsed or refractory large B-cell lymphoma: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2021. http://dx.doi.org/10.37766/inplasy2021.9.0045.