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Добірка наукової літератури з теми "B ce"

Автор: Grafiati

Опубліковано: 8 листопада 2023

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Статті в журналах з теми "B ce"

Liao, P. K., K. E. Spear, and M. E. Schlesinger. "The B-Ce (Boron-Cerium) system." Journal of Phase Equilibria 18, no. 3 (June 1997): 280–83. http://dx.doi.org/10.1007/bf02647853.

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Li, Zhu-bai, Dong-shan Wang, Zhi-xin Zhang, Xue-feng Zhang, Feng-xia Hu, Ji-rong Sun, and Bao-gen Shen. "Gd substitution for Ce in preparing (Ce,Gd)-Fe-B magnets." Journal of Alloys and Compounds 729 (December 2017): 988–91. http://dx.doi.org/10.1016/j.jallcom.2017.09.243.

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Bougle, D., F. Bureau, and J. F. Duhamel. "Reply to CE Casey." American Journal of Clinical Nutrition 49, no. 6 (June 1, 1989): 1329–30. http://dx.doi.org/10.1093/ajcn/49.6.1329-b.

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QIAN, WEI, HAOTIAN CHEN, CHENQI FENG, LIYING ZHU, HUANMING WEI, SHENG HAN, GUISHENG LI, HUALIN LIN, and JIBO JIANG. "MICROSTRUCTURE AND PROPERTIES OF THE Ni–B AND Ni–B–Ce ULTRASONIC-ASSISTED ELECTROLESS COATINGS." Surface Review and Letters 25, no. 06 (August 2018): 1950006. http://dx.doi.org/10.1142/s0218625x19500069.

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We successfully obtained Ni–B and Ni–B–Ce coatings with and without sonication on low-carbon steel (Q235) through electroless plating with the deposition time of 60[Formula: see text]min. The surface morphology and elemental composition of the coatings were evaluated by scanning electron microscopy (SEM) and inductively coupled plasma (ICP). The 11[Formula: see text][Formula: see text]m thick sonicated Ni–B–Ce (Son-Ni–B–Ce) coating is uniform with the composition of Ni 87.1%, B 6.2% and Ce 6.6%. X-ray diffraction (XRD) measurements implied a typical broaden peak around 44∘, considered as amorphous structure which was confirmed by selected area electron diffraction pattern (SAED). Atomic force microscopy (AFM) showed a typical circular pit of Ni–B–Ce coating and Son-Ni–B–Ce coating. X-ray photoelectron spectroscopy (XPS) revealed the chemical status of coating components. The mechanical and corrosion resistance properties were determined by Vickers hardness tester, potentiodynamic polarization (Tafel) and electrochemical impedance spectroscopy (EIS) in 3.5[Formula: see text]wt. % NaCl solution. As a result, the Son-Ni–B–Ce coating revealed the optimum hardness (956[Formula: see text]HV), minimum roughness [Formula: see text] (92.38[Formula: see text]nm) and excellent corrosion resistance (3.65[Formula: see text][Formula: see text]Acm[Formula: see text] among all coatings.

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Wang, C. P., Y. Shi, D. Wang, Y. Lu, D. L. Zhao, and X. J. Liu. "Thermodynamic assessment of the B–Ce and B–Pr systems." Calphad 41 (June 2013): 150–55. http://dx.doi.org/10.1016/j.calphad.2013.03.001.

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Fan, Xiaodong, Shuai Guo, Kan Chen, Renjie Chen, Don Lee, Caiyin You, and Aru Yan. "Tuning Ce distribution for high performanced Nd-Ce-Fe-B sintered magnets." Journal of Magnetism and Magnetic Materials 419 (December 2016): 394–99. http://dx.doi.org/10.1016/j.jmmm.2016.06.048.

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Huang, Min, Zhiqiang Qiu, Fang Wang, Hubin Luo, Changping Yang, and Jian Zhang. "The Effects of Forming CeFe2 on Phase Structure and Magnetic Properties in Ce-Rich Nd-Ce-Fe-B Permanent Magnetic Materials." Materials 14, no. 20 (October 14, 2021): 6070. http://dx.doi.org/10.3390/ma14206070.

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The decomposition of the Nd-Ce-Fe-B phase to form CeFe2 has been usually believed to have an important positive effect on the magnetic properties of Nd-Ce-Fe-B permanent magnetic materials. In this work, a new decomposition process of the Nd-Ce-Fe-B phase on the formation of the CeFe2 phase was observed to play a negative role in its magnetic properties. It is demonstrated that the Nd-Ce-Fe-B phase decomposes into non-magnetic CeFe2, accompanied by the precipitation of Fe soft-phase. The kinks usually occurring in the demagnetization curves of Ce-rich Nd-Ce-Fe-B magnets have been determined to be related to the Fe soft-phase. Instead of using CeFe2 as a grain-boundary phase, another Ce-Cu boundary phase has been explored to efficiently improve the coercivity of Ce-rich Nd-Ce-Fe-B magnets, provided that the Ce-Cu boundary phase has an appropriate Ce to Cu ratio. The present results contribute to the mechanism comprehension and high-performance design of Nd-Ce-Fe-B permanent magnetic materials.

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Lecco, Margherita. "L’enracinement folklorique du Lai de Tydorel ." Fabula 63, no. 3-4 (November 1, 2022): 394–404. http://dx.doi.org/10.1515/fabula-2022-0022.

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Abstrait Le Lai de Tydorel (fin du XIIe siècle) porte des traces importantes d’éléments folkloriques, que l’on peut identifier à la lumière des répertoires de motifs narratifs de Thompson et de Guerreau-Jalabert. Nous lisons ici le texte en ce sens, en repérant deux motifs principaux, qui en fournissent le schéma général, ainsi que deux motifs de moindre envergure, mais tout aussi importants dans l’économie du texte.

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Kolchugina, Nataliya, Tatiana Dobatkina, Vladimir Cheverikin, and Nikolay Dormidontov. "B-Ce-Fe Ternary Phase Diagram Evaluation." MSI Eureka 85 (October 21, 2020): 10.10264.1.5. http://dx.doi.org/10.7121/msi-eureka-10.10264.1.5.

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OGURA, SHUN-ICHIRO, YUTAKA FUJITA, TOSHIAKI KAMACHI, and ICHIRO OKURA. "Preparation of chlorin e6–monoclonal antibody conjugate and its effect for photodynamic therapy." Journal of Porphyrins and Phthalocyanines 05, no. 05 (May 2001): 486–89. http://dx.doi.org/10.1002/jpp.351.

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Chlorin e6 ( Ce 6) was conjugated with anti-tumor monoclonal antibody ( IgG 2 b ) to increase its binding affinity for tumors. The Ce 6 was activated by N -hydroxysuccinimide and directly conjugated with IgG 2 b ( IgG 2 b – Ce 6) via peptide bonds. An average of 11 Ce 6 molecules were coupled to each IgG2b molecule. IgG 2 b – Ce 6 showed high cellular uptake in tumor cells and high photocytotoxicity. These results indicate IgG 2 b – Ce 6 is a good photosensitizer with high binding affinity to tumor cells.

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Більше джерел

Дисертації з теми "B ce"

Lindon, Edward. "Qu'est-ce que la philosophie africaine?" Thesis, University of Nottingham, 2003. http://eprints.nottingham.ac.uk/13357/.

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This thesis traces the evolution of the concept of African philosophy through three phases: the cultural essentialism of Léopold Senghor, founder of Négritude, the universalist critical reaction of Paulin Hountondji and the professional philosophers, and the sophisticated particularism of Valentin Mudimbé. The three stages are contextualized with discussion of the socio-political positioning of each writer, his motives, and his particular understanding of what is at stake in the definition of African philosophy. The initial need to bring about a revalorization of African culture and a recognition of African philosophical capabilities is met by a flamboyant and highly vocal cultural movement, Négritude, which is, however, intrinsically limited in scope and lifespan, and sets up a number of persistent, dogmatic suppositions about the ‘essentially African reason’. A demonstration of the Western origins of this essentialism debunks but does not dispel its influence, since it is firmly anchored to the themes of authenticity, colonial influence, and postcolonial independence. This leads to a dilemma where any move to separate African philosophy from the notion of a distinctly African reason is perceived as a Eurocentric attempt at acculturation, or a capitulation to the false universalism of ‘Enlightenment philosophy’, and on the other hand, the view that African thought is essentially different from European thought is also criticized as deriving from the Western colonial discourse. There is no definitive answer to this problem, and even the search for such an answer is itself part of the problem, a further twist in the ruse that Mudimbé believes is inherent to the colonial discourse. The practical solution Mudimbé proposes is to introduce an écart between African scientific practice and the West, to create a new space within which Africans might investigate the field of their experience in an Afrocentric way which will preserve their cultural specificity.

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MESQUITA, Pedro Pucci de. "O Pronaf B e a Pobreza Rural no Município de Caucaia, Estado do Ceará." www.teses.ufc.br, 2009. http://www.repositorio.ufc.br/handle/riufc/5932.

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MESQUITA, Pedro Pucci de. O Pronaf B e a Pobreza Rural no Município de Caucaia, Estado do Ceará. 2009. 69f. – Dissertação (Mestrado) – Universidade Federal do Ceará, Programa de Pós-graduação em Avaliação de Políticas Públicas, Fortaleza (CE), 2009.
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This dissertation develops a perspective of the microcredit as combat instrument of the rural poverty, tends in view the experience of the Program PRONAF B as effective instrument of social inclusion of the most lacking population, through employment generation and income, necessary to the eradication of the poverty in Brazil. Such it conjectures it is based, above all, in the effectiveness of the Program PRONAF B, considered a form of fast credit, without bureaucracy and solemnity-maintainable. It is discussed the concept and dimension of the poverty in Brazil, with special prominence the Northeast area; the rural society; agricultural politics and family agriculture. It is criticized to the causes and the origin of the poverty, to the point of review as a group compound of social facts that demands a new avaliation of the State and of the society. For this road, to be reached the eradication of the poverty in the future, it is necessary, to create opportunities so that the poor population is integrated the consumption society through microcredit programs, that provide the correction of the facts social that causes of the poverty.
A presente dissertação desenvolve a perspectiva do microcrédito como instrumento de combate à pobreza rural, tendo como referência o Programa PRONAF B como mecanismo de inclusão social da população mais carente, através de geração de renda. Os objetivos deste trabalho são as identificações do perfil sócio-econômico dos beneficiários do PRONAF B, residentes em Caucaia, e das possíveis alterações nas variáveis econômicas da população local. Para a utilização da pesquisa foram utilizados dados primários e secundários, obtidos, respectivamente, através de entrevistas e levantamento nos arquivos locais dos bancos de desenvolvimento e federações de agricultores locais. Discute-se, assim, o conceito e dimensão da pobreza no Brasil, com especial destaque a região Nordeste; a sociedade rural; política agrícola e agricultura familiar. Critica-se a origem da pobreza, a ponto de reclassificá-la como um conjunto complexo de fatos sociais que exigem uma reavaliação do Estado e da sociedade. Por esta via, para se alcançar a erradicação da pobreza, é necessário que se crie oportunidades para que a população pobre seja integrada à sociedade de consumo, através de programas de microcrédito, que proporcionem a correção dos fatos sociais desencadeadores da pobreza. Tudo isso induz à conclusão de que discutir simplesmente a pobreza como um problema de renda não constituirá em solução para o problema.

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Maciel, Iracy Soares Ribeiro. "AvaliaÃÃo da Metodologia do Agroamigo em Caucaia-CE." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=3078.

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nÃo hÃ
A proposta desta dissertaÃÃo Ã avaliar o Programa de MicrocrÃdito Rural do BNB, o Agroamigo, sob o ponto de vista da qualificaÃÃo do processo de crÃdito do Pronaf Grupo B. Esta linha de crÃdito do Programa Nacional de Fortalecimento da Agricultura Familiar (Pronaf) destina-se aos mais pobres entre os agricultores familiares. Nesta perspectiva, a pesquisa envolveu 41 agricultores do municÃpio de Caucaia-CE, alÃm dos membros das diversas instituiÃÃes que intermedeiam essa polÃtica pÃblica. A despeito das adversidades enfrentadas na execuÃÃo do Programa, a pesquisa revela que a implementaÃÃo da referida metodologia conferiu qualidade ao processo de concessÃo de crÃdito no Ãmbito do Pronaf B. Os principais resultados percebidos relacionam-se aos seguintes aspectos: grau de compreensÃo das condiÃÃes do financiamento, adequaÃÃo do crÃdito Ãs necessidades do agricultor e da atividade desenvolvida por ele e sua famÃlia, agilidade do processo, proximidade e acompanhamento, Ãndices de adimplÃncia e de financiamento de atividades nÃo-agropecuÃrias. Complementarmente, foram investigados aspectos inerentes Ãs condiÃÃes de vida desses agricultores, Ã forma de organizaÃÃo e participaÃÃo social que desenvolvem, bem como ao inter-relacionamento entre eles e as instituiÃÃes mediadoras do crÃdito, e destas entre si.
The purpose of this dissertation is to evaluate BNBâs Rural Microcredit Program, the âAgroamigoâ, under the perspective of the qualification of Pronaf Group B process of credit. This credit line of the National Program for Strengthening Family Agriculture (Pronaf) is designed to the poorest among the family farmers. The research involved 41 farmers in the municipality of Caucaia-CE besides the members of the different institutions that intermediate this public policy. Despite the adversities faced in the execution of the Program, the research reveals that the implementation of the referred methodology has added quality to the process of credit concession regarding the Pronaf B. The main results perceived are related to the following aspects: degree of comprehension of the financing conditions, adequacy of the credit to the farmerâs needs and to the kind of activity developed by him and his family, process agility, proximity and follow-up, payment rates and financing of non-agropecuary activities rates. In addition, we have investigated some aspects inherent to these farmersâ life conditions, to their way of organization and the social participation they develop, as well as to the interrelationship between them and the institutions which mediate the credit, and these institutions among themselves.

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MACIEL, Iracy Soares Ribeiro. "Avaliação da metodologia do Agroamigo em Caucaia-Ce." www.teses.ufc.br, 2008. http://www.repositorio.ufc.br/handle/riufc/2515.

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MACIEL, Iracy Soares Ribeiro. Avaliação da metodologia do Agroamigo em Caucaia-Ce. 2008. 254 f. Dissertação (Mestrado em Avaliação de Políticas Públicas) – Universidade Federal do Ceará, Pro - Reitoria de Pesquisa e Pós-Graduação, Programa de Pós-Graduação em Avaliação de Políticas Públicas, Fortaleza-CE, 2008.
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The purpose of this dissertation is to evaluate BNB’s Rural Microcredit Program, the “Agroamigo”, under the perspective of the qualification of Pronaf Group B process of credit. This credit line of the National Program for Strengthening Family Agriculture (Pronaf) is designed to the poorest among the family farmers. The research involved 41 farmers in the municipality of Caucaia-CE besides the members of the different institutions that intermediate this public policy. Despite the adversities faced in the execution of the Program, the research reveals that the implementation of the referred methodology has added quality to the process of credit concession regarding the Pronaf B. The main results perceived are related to the following aspects: degree of comprehension of the financing conditions, adequacy of the credit to the farmer’s needs and to the kind of activity developed by him and his family, process agility, proximity and follow-up, payment rates and financing of non-agropecuary activities rates. In addition, we have investigated some aspects inherent to these farmers’ life conditions, to their way of organization and the social participation they develop, as well as to the interrelationship between them and the institutions which mediate the credit, and these institutions among themselves.
A proposta desta dissertação é avaliar o Programa de Microcrédito Rural do BNB, o Agroamigo, sob o ponto de vista da qualificação do processo de crédito do Pronaf Grupo B. Esta linha de crédito do Programa Nacional de Fortalecimento da Agricultura Familiar (Pronaf) destina-se aos mais pobres entre os agricultores familiares. Nesta perspectiva, a pesquisa envolveu 41 agricultores do município de Caucaia-CE, além dos membros das diversas instituições que intermedeiam essa política pública. A despeito das adversidades enfrentadas na execução do Programa, a pesquisa revela que a implementação da referida metodologia conferiu qualidade ao processo de concessão de crédito no âmbito do Pronaf B. Os principais resultados percebidos relacionam-se aos seguintes aspectos: grau de compreensão das condições do financiamento, adequação do crédito às necessidades do agricultor e da atividade desenvolvida por ele e sua família, agilidade do processo, proximidade e acompanhamento, índices de adimplência e de financiamento de atividades não-agropecuárias. Complementarmente, foram investigados aspectos inerentes às condições de vida desses agricultores, à forma de organização e participação social que desenvolvem, bem como ao inter-relacionamento entre eles e as instituições mediadoras do crédito, e destas entre si.

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Silva, Júlio César da Costa [UNESP]. "A poluição no rio Cocó, sub-bacia B-2, margem direita, e a expansão urbana de Fortaleza-CE." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/104411.

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A ocupação urbana sem planejamento adequado nas cidades tem causado impactos significativos sobre o meio ambiente e, este fato, afeta diretamente a população que sofre com a queda do nível das condições de qualidade da água nos recursos hídricos em áreas urbanas. Esses impactos no ambiente são facilmente identificados como impermeabilização do solo, aumento do escoamento das águas residuárias e disposição inadequada do lixo. Área selecionada para o estudo da presente pesquisa compreende a região sudeste da cidade de Fortaleza, uma zona adensável, compostas por bairros heterogêneos quanto aos aspectos socioeconômicos e ambientais, desprovida de sistema público de esgotamento sanitário e com um deficiente sistema de drenagem. Nesta região observa-se uma intensa e especulativa ocupação do espaço geográfico decorrente do crescimento da expansão urbana em Fortaleza, com as construções de diversos empreendimentos residenciais e comerciais. Esta pesquisa tem como objetivo geral, diante a problemática exposta, envolvendo a expansão urbana, a especulação imobiliária e a poluição hídrica, analisar e avaliar a qualidade das águas do rio Cocó, sub-bacia B-2, margem direita, e de seus aportes, levantando e discutindo os principais parâmetros físicos, químicos e bacteriológicos de amostras de águas coletadas diretamente no leito do rio e em alguns de seus aportes, como também propor algumas recomendações tendo em vista a sustentabilidade e a qualidade ambiental da área de estudo, a sub-bacia-B2 do rio Cocó na cidade de Fortaleza
Urban occupation without adequate planning in the cities has caused significant impacts on the environment and this directly affects the population that suffers with the decreasing quality level of the water from water resources in urban areas. These environmental impacts are easily identifiable: soil sealing, increase of wastewater drainage and inadequate waste disposal. The selected area for this research is the southeast region of Fortaleza: a densely populated area; comprising – concerning socioeconomic and environmental aspects – heterogeneous neighborhoods; devoided of sanitary sewage system; and with a poor drainage system. In this region it can be observed an intense and speculative occupation of the geographical space due to the urban growth in Fortaleza, by the building of diverse residential and commercial enterprises. This research has as objective, concerning the above-mentioned problems, involving urban expansion, real estate speculation and water pollution, to analyze and evaluate the water quality of the Cocó river, sub-basin B-2, right margin, and of its tributaries, raising and discussing main physical, chemical and bacteriological parameters of water samples collected directly from the river and some of its tributaries, as well as to propose some recommendations aiming sustainability and the environmental quality of the studied area, the Cocó river, sub-basin B2 in Fortaleza

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Silva, Júlio César da Costa. "A poluição no rio Cocó, sub-bacia B-2, margem direita, e a expansão urbana de Fortaleza-CE /." Rio Claro, 2013. http://hdl.handle.net/11449/104411.

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Orientador: João Afonso Zavattini
Banca: Mabel Calina de França Paz
Banca: Marisete Dantas de Aquino
Banca: Natale Chierice Junior
Banca: Sandra Elisa Contri Pitton
Resumo: A ocupação urbana sem planejamento adequado nas cidades tem causado impactos significativos sobre o meio ambiente e, este fato, afeta diretamente a população que sofre com a queda do nível das condições de qualidade da água nos recursos hídricos em áreas urbanas. Esses impactos no ambiente são facilmente identificados como impermeabilização do solo, aumento do escoamento das águas residuárias e disposição inadequada do lixo. Área selecionada para o estudo da presente pesquisa compreende a região sudeste da cidade de Fortaleza, uma zona adensável, compostas por bairros heterogêneos quanto aos aspectos socioeconômicos e ambientais, desprovida de sistema público de esgotamento sanitário e com um deficiente sistema de drenagem. Nesta região observa-se uma intensa e especulativa ocupação do espaço geográfico decorrente do crescimento da expansão urbana em Fortaleza, com as construções de diversos empreendimentos residenciais e comerciais. Esta pesquisa tem como objetivo geral, diante a problemática exposta, envolvendo a expansão urbana, a especulação imobiliária e a poluição hídrica, analisar e avaliar a qualidade das águas do rio Cocó, sub-bacia B-2, margem direita, e de seus aportes, levantando e discutindo os principais parâmetros físicos, químicos e bacteriológicos de amostras de águas coletadas diretamente no leito do rio e em alguns de seus aportes, como também propor algumas recomendações tendo em vista a sustentabilidade e a qualidade ambiental da área de estudo, a sub-bacia-B2 do rio Cocó na cidade de Fortaleza
Abstract: Urban occupation without adequate planning in the cities has caused significant impacts on the environment and this directly affects the population that suffers with the decreasing quality level of the water from water resources in urban areas. These environmental impacts are easily identifiable: soil sealing, increase of wastewater drainage and inadequate waste disposal. The selected area for this research is the southeast region of Fortaleza: a densely populated area; comprising - concerning socioeconomic and environmental aspects - heterogeneous neighborhoods; devoided of sanitary sewage system; and with a poor drainage system. In this region it can be observed an intense and speculative occupation of the geographical space due to the urban growth in Fortaleza, by the building of diverse residential and commercial enterprises. This research has as objective, concerning the above-mentioned problems, involving urban expansion, real estate speculation and water pollution, to analyze and evaluate the water quality of the Cocó river, sub-basin B-2, right margin, and of its tributaries, raising and discussing main physical, chemical and bacteriological parameters of water samples collected directly from the river and some of its tributaries, as well as to propose some recommendations aiming sustainability and the environmental quality of the studied area, the Cocó river, sub-basin B2 in Fortaleza
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Jagerschmidt, Alexandre. "Caractérisation des ARNm cérébraux codant pour le récepteur CCK-B de rat et étude structure/fonction de ce récepteur." Paris 5, 1995. http://www.theses.fr/1995PA05P619.

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Ben, Haj Salah Khoubaib. "Substitution de la liaison amide par un triazole 1,4- disubstitué dans le but d’étudier l’impact de ce remplacement sur la structure secondaire et l’activité biologique de peptides." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS003/document.

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La réaction de cycloaddition entre un azoture et un alcyne catalysée par le cuivre (I) (CuAAC) pour former un 1,2,3-triazole 1,4-disubstitué est très utilisée dans de nombreux domaines de la chimie. Cette réaction a très vite été utilisée en synthèse peptidique notamment du fait du caractère isostère du noyau triazole et de la liaison amide. Toutefois l'impact de l'insertion d'un triazole sur la structure secondaire de peptides n'a été que faiblement exploré. Ainsi, pour étudier l'effet d'un tel remplacement nous avons choisi deux peptides modèles structurés le premier modèle est un peptide linéaire de la famille des peptaibols et le second est un peptide cyclique la tamandarine B. Dans un premier temps, nous avons optimisé une voie de synthèse de peptaibols que nous avons appliqué à l'alaméthicine F50/5 et à un analogue de la bergofungine D. Pour cela, nous avons utilisé une synthèse peptidique en phase solide sous irradiation micro-ondes en profitant d'un cocktail de réactifs efficaces contenant du diisopropylcarbodiimide comme agent de couplage et de l'oxyma. Cette méthode de synthèse a été étendue à l'obtention d'analogues silylés de l'alamethicine en substituant dans différentes positions l'acide aminobutyrique par un résidu hydrophobe et encombré : la bis-triethylsilyl-dipropylglycine (TES-Dpg). Dans la deuxième partie nous avons développé la synthèse de dipeptides à motif triazole. Puis nous avons défini les conditions réactionnelles nécessaires pour leur utilisation en SPPS et synthétisé des peptides contenant plusieurs motifs triazoles. Ces dipeptides ont ensuite été utilisés pour réaliser un scan triazole sur les deux peptaibols modèles. Les études structurales par dichroïsme circulaire, RMN et les tests biologiques de différents analogues nous permettent de conclure que le triazole affecte la structure secondaire des peptaibols et par conséquence induit une perte d'activité. Ainsi il apparaît que le concept de triazole comme isostère de la liaison peptidique doit être employé avec prudence. Dans l'optique de comprendre l'impact de triazole sur l'activité et la structure secondaire de peptides cycliques, nous avons généré des analogues simplifiés de la tamandarine B un depsipeptide cyclique d'origine marine. Nous rapportons les résultats préliminaires de cette étude
The cycloaddition reaction between an azide and an alkyne catalyzed by copper (I) (CuAAC) to form a 1,2,3-triazole 1,4-disubstituted is widely used in many areas of chemistry. This reaction was rapidily used in peptide synthesis because of the isosteric nature between the triazole ring and the amide bond. However, impact of the insertion of a triazole on the secondary structure of peptides was only scarcely explored. Thus, to study the effect of such a replacement we chose two models of structured peptides. The first models are linear peptides of the peptaibols family and the second is the cyclic peptide tamandarin B.First, we have optimized a peptaibols synthesis that was applied to alamethicin F50 / 5 and to an analog of bergofungin D. For this we used a solid phase peptide synthesis under microwave irradiation taking advantage of the efficient cocktail consisting of diisopropylcarbodiimide as a coupling agent and Oxyma. This synthesis has been extended to silylated analogues of alamethicin by substituting in different positions the aminobutyric acid by the hydrophobic and crowded residue: bis-triethylsilyl-dipropylglycine (Dpg-TES).In the second part we have developed the synthesis of dipeptides containing a triazole motif. Then we defined the reaction conditions necessary for their use in SPPS and synthesized peptides containing several triazoles rings. These dipeptides were then used to perform a triazole scan on the two peptaibols models. The structural studies by circular dichroism, NMR and biological tests of various analogs allow us to conclude that the triazole affect the secondary structure of peptaibols and consequently induces a loss of activity. Thus it appears that the concept of triazole as isosteric of the peptide bond should be used with caution.In order to understand the triazole impact on the activity and the secondary structure of cyclic peptides, we generated simplified cyclic analogues of tamandarin B a depsipeptide of marine origin. We report the preliminary results of this study

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Le, Nouën Cyril. "Étude de l'épidémiologie moléculaire du segment B de l'avibinavirus de la bursite infectieuse aviaire et bases moléculaires de la virulence chez ce virus." Lyon 1, 2006. http://www.theses.fr/2006LYO10022.

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La bursite infectieuse est une maladie du poulet (Gallus gallus) causée par un virus (noté IBDV) de la famille des Birnaviridae, genre Avibirnavirus. Certaines souches d'IBDV dites hypervirulentes (vvIBDV) induisent une mortalité supérieure à 30 %. Il n'y a pas de marqueur génétique de virulence pour les caractériser. Afin de comparer l'épidémiologie moléculaires des deux segments génomiques de l'IBDV, notés A et B, de courtes régions génomiques phylogénétiquement représentatives de chacun des segments ont été identifiées, en comparant les phylogénies dérivées de séquences nucléotidiques complètes ou partielles déjà publiées. Ces régions correspondent au tiers moyen du gène VP2 (segment A) et aux deux tiers 5' du gène VP1 (segment B). Ces régions ont été amplifiées et séquencées chez 50 souches virales d'origines et de phénotypes variés. Leur étude phylogénétique suggère que les segments génomiques ont co-évolué chez 70 % des virus étudiés (dont les vvIBDV), mais que des phénomènes de réassortiment pourraient avoir affecté 13 % des souches virales. Un des virus potentiellement réassortant (segment A apparenté aux vvIBDV, segment B non vvIBDV), inoculé expérimentalement à des poulets sensibles, avait un pouvoir pathogène réduit sans que la réplication virale apparaisse modifiée. Les bases moléculaires de la pathogénicité de l'IBDV ont finalement été recherchées chez deux souches virales apparentées aux vvIBDV identifiées lors de l'étude phylogénétique, l'une issue d'une lignée particulière de virus pathogènes (88180), l'autre apparentée aux vvIBDV typiques mais dotée d'un pouvoir pathogène réduit (94432). Un système de génétique inverse a été développé pour chacune. Le pouvoir pathogène in vivo des clones moléculaires correspondants s'est avéré comparable à celui des virus parentaux. Onze virus génétiquement modifiés dérivés des clones moléculaires ont été construits et caractérisés in vivo. Le pouvoir pathogène de 88180 semble lié au segment A et à plusieurs régions du segment B, alors que l'atténuation de 94432 s'avère liée à trois mutations peptidiques codées par le segment A.

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Mancini, Bourgine Maryline. "Evaluation de l'immunogénicité d'un vaccin thérapeutique dans un modèle de souris humanisées et transgéniques pour l'antigène de surface du virus de l'hépatite B : application pour le traitement des porteurs chroniques de ce virus." Paris 7, 2007. http://www.theses.fr/2007PA077109.

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Des lignées de souris transgéniques (Tg) pour les protéines d'enveloppe du VHB et les molécules de classe I (HLA-A2) et II (DRB1) du complexe majeur d'histocompatibilité humain ont été créées dans le but de caractériser l'implication de l'antigène HBs (AgHBs) porté par les protéines d'enveloppe lors l'infection chronique par le VHB. Ces souris expriment de manière constitutive l'AgHBs à des taux élevés dans le foie. L'AgHBs est sécrété dans le sérum en l'absence de toute production d'anticorps anti-HBs et de pathologie hépatique. Le statut immunologique des souris triple Tg (AgHBs/HLA-A2/HLA-DRBl) est comparable par plusieurs aspects à celui des porteurs chroniques du VHB infectés à la naissance chez lesquels le virus se multiplie à bas bruit. L'injection d'un plasmide (pCMV-S2. S) codant pour deux des protéines d'enveloppe du VHB permet de rompre la tolérance au niveau des cellules T CD8+. Par contre, le compartiment T CD4+ est tolérisé. La présence mutuellement exclusive des lymphocytes T CD4+ et de F AgHBs souligne le rôle de ce dernier dans le maintien de la tolérance vis à vis des lymphocytes T CD4+. Parrallélement à cette étude, la sécurité et l'immunogénicité d'un vaccin à base d'ADN a été apprécié chez dix porteurs chroniques du VHB dans un essai de phase I de vaccination thérapeutique. Les injections de pCMV-S2. S ont entraîné une diminution marquée de la charge virale chez deux patients et une baisse transitoire de la charge virale de plus de 50% chez quatre autres patients. Des cellules T CD8+ et CD4+ mémoires spécifiques de l'enveloppe du VHB ont été mises en évidence chez tous les patients après vaccination
By using HLA-A2-/HLA-DRl-transgenic H-2 class Wclass II-knockout mice, we have generated transgenic (Tg) mouse lineages expressing the HBV enveloppe proteins in a context of human MHC molecules. The Tg mice express high amount of hepatitis B surface antigen (HBsAg) carried by the envelope proteins in the liver. The HBsAg is secreted and present in the serum of mice during the animal's lifetime. This preclinical humanized mice model mimics in some aspects the tolerance to HBsAg observed in chronic HBV carriers. As a therapeutic tool, a DNA plasmid encoding the small and the middle protein of HBV was used to immunize Tg mice. Despite a high concentration of HBsAg in sera, injection of this DNA induced a high frequency of CD8+ T cells secreting IFNgamma. Nevertheless, the DNA-based immunization elicited no CD4+ T cell responses. However, when pro-inflammatory stimuli were given before or after DNA-based immunization, the HBsAg was cleared from the serum. This model provides evidence that HBsAg displayed a strong tolerogenic effect on the CD4+ T cell compartment. We also carried out a phase I trial evaluating tolerance to vaccination with a naked DNA vaccine encoding the small and middle envelope proteins in ten patients chronically infected with HBV who did not respond to existing treatments. This vaccination was well tolerated. In two patients a decrease in viral DNA levels accompanied by an HBe/anti-HBe seroconversion was observed. In four other patients the decrease was only transient, even if a fourth injection was given. However, after genetic vaccination, we demonstrated the induction or reactivation of IFNgamma-secreting envelope-specific T-cells in ail patients

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Книги з теми "B ce"

Naus, D. SEN wide-plate crack-arrest tests using A 533 grade B class 1 material: WP-CE test series. Washington, DC: Division of Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, 1989.

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Zāhī, ʻAlī ibn Isḥaq, 930 or 31-963 or 4., ред. A poet of the Abbasid period: Abū al-Qāsim al-Zāhi (ʻAlī b. Isḥāq b. Khalaf al-Zāhī) 313-352 AH/925-963 CE : his life and poetry. Wiesbaden: Harrassowitz, 2010.

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Sindāwī, Khālid. A poet of the Abbasid period: Abū al-Qāsim al-Zāhi (ʻAlī b. Isḥāq b. Khalaf al-Zāhī) 313-352 AH/925-963 CE : his life and poetry. Wiesbaden: Harrassowitz, 2010.

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Fan, Xianrui, and Zhifu Shi. Guo jia gong wu yuan lu yong kao shi gong gong ke mu zhuan yong jiao cai: Xing zheng zhi ye neng li ce yan(A, B)Lei jing dian fu xi fang an. Beijing: Zhong guo tie dao chu ban she, 2004.

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Boularbah, Hakim, and Michel Binard. Le nouveau droit de l'expertise judiciaire en pratique : $b commentaire de la loi du 15 mai 2007 modifiant le Code judiciaire en ce qui concerne l'expertise et de sa loi de "réparation" du 30 décembre 2009. 2nd ed. Bruxelles: Larcier, 2010.

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B-Ce-Abs-NT 106321. Not Avail, 1999.

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B-Ce-Abs-NT 106270. Not Avail, 1999.

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Scourfield, J. H. D. Claudian, poet, b. c. 370 CE. Oxford University Press, 2015. http://dx.doi.org/10.1093/acrefore/9780199381135.013.1607.

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Norman, Mailer. Ce Marilyn Monroe Art Ed. B. Taschen Benedikt Verlag Gmbh., 2011.

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Частини книг з теми "B ce"

Predel, B. "B - Ce (Boron - Cerium)." In B - Ba … Cu - Zr, 28–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_7.

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Predel, B. "Ca - Ce (Calcium - Cerium)." In B - Ba … Cu - Zr, 156. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_107.

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Predel, B. "Cd - Ce (Cadmium - Cerium)." In B - Ba … Cu - Zr, 174. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_120.

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Predel, B. "Ce - Co (Cerium - Cobalt)." In B - Ba … Cu - Zr, 190–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_134.

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Predel, B. "Ce - Cu (Cerium - Copper)." In B - Ba … Cu - Zr, 193. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_135.

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Predel, B. "Ce - Fe (Cerium - Iron)." In B - Ba … Cu - Zr, 194. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_136.

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Predel, B. "Ce - Ga (Cerium - Gallium)." In B - Ba … Cu - Zr, 195–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_137.

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Predel, B. "Ce - In (Cerium - Indium)." In B - Ba … Cu - Zr, 197. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_138.

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Predel, B. "Ce - Ir (Cerium - Iridium)." In B - Ba … Cu - Zr, 198. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_139.

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Predel, B. "Ce - Li (Cerium - Lithium)." In B - Ba … Cu - Zr, 199. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-44756-6_140.

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Тези доповідей конференцій з теми "B ce"

Chen, Z., Y. Lim, and D. Brown. "Substitution of Ce for NdPr in melt-spun (NdPr)-Fe-B powders." In 2015 IEEE International Magnetics Conference (INTERMAG). IEEE, 2015. http://dx.doi.org/10.1109/intmag.2015.7156671.

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Zhang, J., L. Zhao, X. Liao, H. Zeng, and Z. Liu. "Effects of Ta doping and Ce reduction on the magnetic proper-ties and thermal stability of Ce-Fe-B alloys." In 2018 IEEE International Magnetic Conference (INTERMAG). IEEE, 2018. http://dx.doi.org/10.1109/intmag.2018.8508068.

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Hajek, Karel. "Efficiency of the class B-CE and class B-CC high-voltage wideband amplifiers with a capacitive load." In 2011 21st International Conference Radioelektronika (RADIOELEKTRONIKA 2011). IEEE, 2011. http://dx.doi.org/10.1109/radioelek.2011.5936430.

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Li, A., W. Li, S. Huang, J. Wang, H. Feng, and M. Zhu. "The study on grain-boundary microstructure of sintered (Ce, Nd)-Fe-B magnets." In 2015 IEEE International Magnetics Conference (INTERMAG). IEEE, 2015. http://dx.doi.org/10.1109/intmag.2015.7156666.

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Peng, B., Y. Liu, J. Jin, and M. Yan. "Enhanced coercivity of Nd-Ce-Y-Fe-B sintered magnets by adding (Pr, Nd)-H powders." In 2018 IEEE International Magnetic Conference (INTERMAG). IEEE, 2018. http://dx.doi.org/10.1109/intmag.2018.8508075.

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Pandey, Abhishek, C. Mazumdar, R. Ranganathan, S. Dattagupta, V. R. Reddy, A. Gupta, Amitabha Ghoshray, and Bilwadal Bandyopadhyay. "Intermediate Valence Behavior In Ce[sub 0.5]Eu[sub 0.5]Pd[sub 3]B[sub x]." In MAGNETIC MATERIALS: International Conference on Magnetic Materials (ICMM-2007). AIP, 2008. http://dx.doi.org/10.1063/1.2928948.

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Kolber, Michael. "Soft Tissue Fixation and Implant Development: Regulatory." In ASME 2009 4th Frontiers in Biomedical Devices Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/biomed2009-83074.

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OVERVIEW: a. The Art of Regulatory Science. What engineers should know about the regulatory process. Getting your class 1 or 2 device market cleared in the US. b. What about Europe. CE mark, Notified Bodies, Competent Authorities and other interesting facts. c. Regulatory pitfalls.

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Rojas Kolomiets, Ekaterina, Michael Bizimis, Gene Yogodzinski, Jeffrey Ryan, Owen Jensen, and Lukáš Ackerman. "Heavy Mo isotope signatures and high B/Ce reveal a serpentinite source in the Aleutian arc lavas." In Goldschmidt2022. France: European Association of Geochemistry, 2022. http://dx.doi.org/10.46427/gold2022.12292.

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Daleyev, Dalel, Shervin Rasoulzadeh, and Iva Kovacic. "A Novel Approach of Structural FE Modelling Using 4D Architectural Design Sketches." In 6th IPMA SENET Project Management Conference “Digital Transformation and Sustainable Development in Project Management”. International Project Management Association, IPMA Publications, and Faculty of Civil Engineering, University of Zagreb, Croatia, 2023. http://dx.doi.org/10.5592/ce/senet.2022.23.

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This paper describes a novel methodology for a quick structural finite element (FE) modelling of free-form and high-rise structures sketched within a developed 4D semantic, mixed reality sketching application, targeted for early stages of architectural design, followed by a shape inference pipeline. The novel approach presented in this paper intends to estimate structural viability for the architectural concept in the early preliminary draft. A fast collaborative export of geometrical data from the sketching app to the generative algorithm for the assembling of structural topology will be used to define analytical FE model. With pre-defined data, such as material information and the type of load-bearing system, a simple linear-elastic FE calculation will be conducted in order to analyse the structural parts in ultimate (ULS) and serviceability limit states (SLS) and point out the problematic places. Once the decision regarding the architectural design of the sketched structure is made, the compiled FE model will be afterwards transferred to a commercial FE software in order to undergo further, more detailed structural analysis. The advantage of the described modelling method is a) time saving as it generates a model directly upon architectural design, and b) by generation of the plausible FE model in the very early stages of planning and post-editing it during the process.

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Jin, J., Z. Qian, G. Bai, B. Peng, Y. Liu, and M. Yan. "Effects of (Nd,Pr)Hx intergranular addition on the mechanical properties of Nd-Pr-Ce-Fe-B sintered magnets." In 2018 IEEE International Magnetic Conference (INTERMAG). IEEE, 2018. http://dx.doi.org/10.1109/intmag.2018.8508619.

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Звіти організацій з теми "B ce"

Naus, D., J. Keeney-Walker, B. Bass, S. Iskander, R. Fields, R. deWit, and S. Low, III. SEN wide-plate crack-arrest tests using A 533 grade B class 1 material: WP-CE test series. Office of Scientific and Technical Information (OSTI), November 1989. http://dx.doi.org/10.2172/5441776.

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De Varela, Ana Lorena, and Silvia Martínez Álvarez. Aprendamos todos a leer: fascículo 35: toda la familia lee y escribe conmigo. Banco Interamericano de Desarrollo, April 2022. http://dx.doi.org/10.18235/0004022.

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Aprendamos Todos a Leer es la iniciativa para la enseñanza de lectura y escritura inicial del BID, donde a través de materiales para el alumno, el maestro y el aula de clase, pretende brindar herramientas para apoyar el proceso de alfabetización inicial. El programa se organiza a partir de una cartelera fonológica presentando para cada fonema (sonido de letra) un personaje caracterizado por un animal. En respuesta al COVID-19, se desarrollaron fascículos para apoyar el trabajo en casa. Este fascículo los niños podrán realizar diferentes actividades para conocer el sonido /S-s/ de la letra C cuando se escribe con las vocales e, i: Ce-ce y Ci-ci. Les ayudaremos a combinarlas con las vocales a, o, u y las consonantes y las consonantes M-m, P-p, N-n, L-l, S-s, F-f, T-t, B-b, D-d, C-c, QU-qu, Y-y, Ll-ll, H-h, Ch-ch, R-r, G-g, J-j.

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Choudhary, Ruplal, Victor Rodov, Punit Kohli, John D. Haddock, and Samir Droby. Antimicrobial and antioxidant functionalized nanoparticles for enhancing food safety and quality: proof of concept. United States Department of Agriculture, September 2012. http://dx.doi.org/10.32747/2012.7597912.bard.

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General concept. The reported 1-year study tested the feasibility ofpreparing antimicrobial and antioxidant nanoparticlesfunctionalized with natural phenolic compounds, as a first step to reach the ultimate goal - improving safely and quality of foods by developing novel antimicrobial and antioxidant food-contacting materials. The secondary objectives of the study were (a) selecting the most promising phenoliccompounds, (b) building nanoparticles with the selected phenolicgrafted on their Surface, and (c) testing antimicrobial and antioxidant properties of these particles. The study was expected to provide a " go/no go" decision as concerning the prospects of phenolic- bound nanoparticles as antimicrobial and antioxidant agents. Results. In course of the feasibility study, curucminwas chosen as the most promising phenoliccompound due to its high antibacterial activity exceeding other tested compounds by at leas one order of magnitude. Lipsome-typephospholipid/polydiacetylene(PDA) nanoparticlesfunctionalizedwith curcuminwere successfully built. The pitfall of limited curcumin amount that could be covalently bound to theparticle surface was circumvented by inclusion of curcunun in the liposome body. It was suggested onthe basis of fluorescence spectroscopy that curcuminwas bound by hydrophobic forces in the bi1ayer periphery of the Liposomesand therefore mightexert a contact effect on microorganisms. The curcumin functionalizednanoparticles(CFN) were shown to have a strong bactericidal activity towards both Gram-negative (E. coli) and Gram-positive (B. ce,·e11s) bacteria, but only limited effect against yeast. Furthermore, beyond the originallyplanned objectives, preliminary trials showed that CFN could be bound to silanized glass surface rendering aנבtiנnicrobial activity to the glass. Tnaddition, the particles showed antioxidantcapacity. Tberefore, it ,vas co11cluded tlוattlוeaims of tlוefeasibility study bad been successfully reached an

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