Готові списки джерел за темами / Anti-novel

Добірка наукової літератури з теми "Anti-novel"

Автор: Grafiati
Опубліковано: 10 грудня 2022
Оновлено: 29 січня 2023

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Статті в журналах з теми "Anti-novel"

1

Tadd Adcox, James. "The Anti-Novel." American Book Review 37, no. 4 (2016): 24–25. http://dx.doi.org/10.1353/abr.2016.0060.

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2

Anil Castelino, Prakash, Dr Jagadeesh Prasad Dasappa, Dr Prashantha Naik, Sharath Chandra K., and Anusha Kumari G. Y. "Mosquito-Larvicidal, Anti-Bacterial and Anti-Fungal Properties of Novel 2, 4-Disubstituted-[1, 3] - Thiazoles." Indian Journal of Applied Research 4, no. 3 (October 1, 2011): 25–31. http://dx.doi.org/10.15373/2249555x/mar2014/9.

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3

Chaban, T. I., V. S. Matiychuk, V. V. Ogurtsov, I. G. Chaban, and I. A. Nektegayev. "Development of effective anti-inflammatory drug candidates among novel thiazolopyridines." Ukrainian Biochemical Journal 92, no. 2 (April 17, 2020): 132–39. http://dx.doi.org/10.15407/ubj92.02.132.

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4

Chang, M. H., H. Y. Koh, Y. S. Cho, and K. I. Choi. "Novel Anti-Pseudomonas Cephalosporins." Current Pharmaceutical Design 3, no. 2 (April 1997): 209–26. http://dx.doi.org/10.2174/138161280302221006120722.

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Abstract: Since the catechol type cephalosporins having a potent activity against P. aeruginosa strain were introduced, many kinds of derivatives have been developed. These cephalosporins adopted various substituents as siderophores such as catechol or pyridone type derivatives at C-7 or C-3 position to facilitate their penetration through the bacterial cell membrane. In this review, the structural specifications of the recently developed cephalosporins and their biological activity against P. aeruginosa bacterial strain would be overviewed.
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5

Kitto, GB. "Novel anti-AIDS immunotoxins." Biofutur 1997, no. 163 (January 1997): 44. http://dx.doi.org/10.1016/s0294-3506(97)89240-x.

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6

Naher, Prof Dr Habeeb Sahib, and Prof Anwar Kadhim AL-Saffar. "Novel Anti- tuberculosis Compound." IOSR Journal of Pharmacy and Biological Sciences 9, no. 5 (2014): 01–05. http://dx.doi.org/10.9790/3008-09510105.

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7

Lohray, Vidya B., Braj B. Lohray, and Brijesh Kumar Srivastava. "Novel anti-infective compounds." Pure and Applied Chemistry 77, no. 1 (January 1, 2005): 195–200. http://dx.doi.org/10.1351/pac200577010195.

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A set of substituted piperazinyloxazolidinone derivatives has been studied for their antibacterial activity in a few gram-positive bacteria. The structural modifications have provided a superior compound than linezolid, the only drug of this class in the market at present.
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8

Proietto, Joseph, Barbara C. Fam, Deborah A. Ainslie, and Anne W. Thorburn. "Novel anti-obesity drugs." Expert Opinion on Investigational Drugs 9, no. 6 (June 2000): 1317–26. http://dx.doi.org/10.1517/13543784.9.6.1317.

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Chandraprabha, V. J. "Novel Thiazoles Derivatives Containing Methoxy-Napthyl Moiety as Potent Anti-Bacterial and Anti-Tubercular Agents and Its Characterization." Journal of Medical Science And clinical Research 04, no. 11 (November 10, 2016): 13759–68. http://dx.doi.org/10.18535/jmscr/v4i11.42.

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Guan, Y. J., J. C. Wang, J. Hu, Y. X. Tian, W. M. Hu, and S. J. Zhu. "A novel fluorescent dual-labeling method for anti-counterfeiting pelleted tobacco seeds." Seed Science and Technology 41, no. 1 (April 1, 2013): 158–63. http://dx.doi.org/10.15258/sst.2013.41.1.18.

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Дисертації з теми "Anti-novel"

1

Gunnam, Mallikarjunareddy. "Novel anti-norovirus therapeutics." Thesis, Wichita State University, 2013. http://hdl.handle.net/10057/6818.

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Noroviruses are the most common cause of acute gastroenteritis, accounting for over 23 million cases annually in the U.S. alone. Norovirus infections constitute an important health problem for which there are no specific antiviral therapeutics or vaccines. In this thesis, (a) structure-activity relationship studies were carried out using the acyclic sulfamide scaffold. Several derivatives based on this scaffold were found to inhibit norovirus in a cell-based replicon system and, (b) a series of bisulfite adducts derived from representative transition state inhibitors (dipeptidyl aldehydes and ?-ketomides) was synthesized and shown to exhibit anti-norovirus activity in a cell-based replicon system. The ED50 of the most effective inhibitor was 60 nM. This study demonstrates for the first time the utilization of bisulfite adducts of transition inhibitors in the inhibition of norovirus 3CL protease in vitro and in a cell-based replicon system. The approach described herein can be extended to the synthesis of the bisulfite adducts of other classes of transition state inhibitors of serine and cysteine proteases, such as ?-ketoheterocycles and ?-ketoesters. Taken together, this thesis describes the discovery of two novel classes of inhibitors of noroviruses.
Thesis (M.S.)--Wichita State University, Fairmount College of Liberal Arts and Sciences, Dept. of Chemistry
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2

Calhoun, McKenzie L. "Novel Anti-Diabetic Medications." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/6885.

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Di, Francesco Angela Maria. "Anti-tumour properties of novel diaziridinylquinones." Thesis, University of Salford, 2001. http://usir.salford.ac.uk/26638/.

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This work is concerned with the synthesis and potential anti-tumour properties of novel Diaziridinylquinones. These types of compounds are usually activated by bioreduction to form cytotoxic species, which alkylate DNA and block cells in the G 2 /M phase of the cell cycle. However, the present studies have concentrated on compounds which appear to function by other mechanisms. Certain phenol/ester derivatives of PDZQ (2,5-diaziridinyl-3-phenyl-l,4-benzoquinone) were significantly more cytotoxic than PDZQ in all of the cell lines investigated (Chapter 3). The esters were cleaved by esterases to form a highly cytotoxic stable meta-phenol or an unstable para-phenol. The compounds were studied in detail using DNA cross-linking, clonogenic, apoptosis and flow cytometry assays. Preliminary studies on the protein tyrosine kinase (PTK) activity of the epidermal growth factor receptor (EGF-R) showed that the |iM concentrations of the meta-phenol can reduce the PTK activity of purified EGF-R by 50%. The overall proposed mechanism is that the cytotoxic esters are cleaved by esterases to form reactive phenols. However, the enhanced toxicities of these compounds are not simply due to the differences in DNA cross-linking efficiencies. It is proposed that the phenols cross-link DNA and inhibit one or more tyrosine kinases. Preliminary tumour xenograft studies suggest that some acridine derivatives of PDZQ have a very high therapeutic index (Chapter 4). These compounds cross-link DNA but there is no DNA-intercalation (from fluorescence, absorbance, DNA-unwinding and T m studies). It is proposed that these compounds can be reduced within a cell and interact with Topoisomerases. RH1 is scheduled for Phase I/II clinical trials and the final chapter of this thesis reports on the induction of apoptosis by this diaziridinylquinone. These studies used many different biochemical/visual techniques to measure apoptosis. The general conclusion from this study is that although RH1 can induce apoptosis, the extent is strongly dependent on the cell line and it is only significant at relatively high concentrations of drug.
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Altaie, Ala. "Novel anti-oxidant properties of cobalamin." Thesis, University of Chester, 2009. http://hdl.handle.net/10034/128965.

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Oxidative stress has been associated with a wide range of diseases, including cardiovascular diseases, Alzheimer's disease, atherosclerosis, Parkinson's disease and cancer. It also plays a role in the ageing process. Hyperhomocysteimia is commonly found to be associated with these diseases. The hyperhomocysteimia is a result of a deficiency in both folate and cobalamin Folate is known to reduce Hey and protect cells from apoptosis, but there are no studies investigating the impact of cobalamin on apoptosis induced by oxidative stress or the mechanism(s) of the protection. The aims of the research are to investigate the protective role of cobalamin and the possible mechanism(s) for this protection. It also examines the protective role of novel cobalamin and investigates their superior protection. The methods used in this research for apoptosis detection we used caspase-3 and the annexin-V, while for necrosis we used PI staining, where cell viability were detected using MTS assay. We also measured the generation of superoxide by Lucigenin-enhanced chemiluminescence and reactive oxygene species by using the redox active prob DCFH-DA. Moreover, the intracellular proteins were measured via staining with specific fluorescent-conjugated antibodies were detected using flowcytometry. Our result demonstrated that 25|iM of cobalamin protects cells from apoptosis. The protection by cobalamin was associated with induction of iHsp72 and iHO-1, and these are shown to be essential for the protection. Furthermore, our research demonstrated a novel mechanism of cobalamin-apoptosis protection involving induction of NfkB, ERK1/2 and AKT signal transduction pathways. In order to protect cells from apoptosis induced by oxidative stress, cobalamin induces the pNfkB which in turn regulate the iNOS and HO-1 induction. Cobalamin also induces thepERK1/2 which regulates the induction of Hps72 and Nrf2. And finally, pAKT induced by cobalamin which regulate the Nrf2 and HO-1 induction. The inhibition of any of theses pathways leads to loss the protection. The GSCbl and NACCbl provide a superior protection against oxidative stress, this protection involved induction of the signal transduction pathways and Hsps. To conclude; cobalamin provides protection against cells death induced by oxidative stress. Cobalamin achieves this by multiple pathways which include direct antioxidant stimulation and induction of signal transduction pathways. Different cobalamin derivatives have superior protections. These finding are a useful pharmaceutical tool in the treatment of the oxidative stress related diseases.
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5

Fu, Yu. "Baicalein, a novel anti-diabetic compound." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/76854.

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Both in type 1 (T1D) and type 2 diabetes (T2D), the deterioration of glycemic control over time is primarily caused by an inadequate mass and progressive dysfunction of ?-cells, leading to the impaired insulin secretion. Thus, the search for agents to protect b-cell and enhance its function is important for diabetes treatment. Studies have reported that baicalein, a flavone originally isolated from the roots of Chinese herb Scutellaria baicalensis, has various claimed beneficial effects on health, such as anti-oxidant, anti-viral, anti-thrombotic, and anti-inflammatory effects. However, it is unclear whether it exerts an anti-diabetic action. Here, we present evidence that baicalein may be a novel anti-diabetic agent. Specifically, dietary intake of baicalein significantly improved hyperglycemia, glucose tolerance, and blood insulin levels in high-fat diet (HFD)-fed middle-aged diabetic mice, which was associated with the improved isle t?-cell survival and mass. Baicalein treatment had no effect on food intake, body weight gain, circulating lipid profile, and insulin sensitivity in HFD-fed mice. In in-vitro studies, baicalein significantly augmented glucose-stimulated insulin secretion in insulin-secreting cells (INS1) and promotes viability of INS1 cells and human islets. These results demonstrate that baicalein may be a naturally occurring anti-diabetic agent by directly modulating pancreatic?-cell function.
Master of Science
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6

Bennett, Andrew Richard. "Novel anti-corrosion coatings on steel." Thesis, Swansea University, 2009. https://cronfa.swan.ac.uk/Record/cronfa42310.

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The primary objective of the work detailed in this thesis was to further explore the inhibitory performance of polyaniline for the prevention of corrosion-driven cathodic disbondment on steels and zinc-alloy coated steels. Polyaniline was investigated under atmospheric conditions so as to make possible further elucidation of the mechanisms by which it would provide this inhibition. Accordingly it is suggested that the positive performance of polyaniline indicated within this report, in addition to further mechanistic understanding, paves the way for industrial use of polyaniline as an inhibitor. To provide further mechanistic support to the inhibitory performance of polyaniline, polyaniline micro-films were applied to the metal substrate surfaces, allowing the visualisation of electrochemical and acid-base state changes resulting from substrate contact and corrosion. Due to industrial concerns over the current cost associated with polyaniline inhibitor pigments, the inhibitory properties of novel organic acid etch primers were explored on both iron and zinc substrates. The findings of this study led to the proposition that the presence of polyaniline may not be required within the model organic coating system in order to provide a similar level of inhibition. Alongside the investigations of inhibitory organic coating systems, attention was directed towards novel Mg-Al-Zn metallic coatings. These are shown to provide inhibition of cathodic disbondment of organic coatings where no form of in-coating inhibition is present. These alloy-coated steels were found to suffer from a novel form of corrosion and full mechanistic proposition is provided, as well as important initiation factors. Finally, the photovoltaic possibilities of polyaniline were explored in order to find novel, high value coating systems for the pre-painted steel industry. Accordingly the photovoltaic properties of polyaniline are compared to established photovoltaic polymers.
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7

Mizuhara, Tsukasa. "Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives." 京都大学 (Kyoto University), 2013. http://hdl.handle.net/2433/174545.

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8

Errey, James C. "Mechanistic studies of novel anti-tuberculosis targets." Thesis, University of East Anglia, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398794.

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9

Seaton, Angela. "Anti-tumour activity of novel phenolic compounds." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324524.

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Gorsuch, Stephen. "Synthetic approaches towards novel anti-HIV agents." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265108.

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Книги з теми "Anti-novel"

1

Gallatin, Michael. Found time: An anti-novel. Ann Arbor, Mich: ProForma Books, 1988.

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2

Colp, Norman. The great American anti-novel. [New York: Norman Colp, 1990.

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3

The great anti-American novel. Henderson, Nevada: H.H.B. Publishing, LLC, 2013.

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4

Marzoeki, Achmad. Pil anti bohong: Novel penggugah inspirasi. Kebumen: Majelis Kajian Peradaban dan Budaya, 2011.

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5

Kahn, Michael, ed. High Throughput Screening for Novel Anti-Inflammatories. Basel: Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8462-4.

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6

Mizuhara, Tsukasa. Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54445-6.

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7

Simmons, David. The Anti-Hero in the American Novel. New York: Palgrave Macmillan US, 2008. http://dx.doi.org/10.1057/9780230612525.

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Pruzanski, Waldemar, and Peter Vadas, eds. Novel Molecular Approaches to Anti-Inflammatory Therapy. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8.

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9

Glynn, Ruth Sarah. Contesting the monument: The anti-illusionist Italian historical novel. Birmingham: University of Birmingham, 1998.

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10

Contesting the monument: The anti-illusionist Italian historical novel. Leeds, England: Northern Universities Press, 2005.

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Частини книг з теми "Anti-novel"

1

Fordham, Finn. "Finnegans Wake: Novel and Anti-novel." In A Companion to James Joyce, 71–89. Oxford, UK: Blackwell Publishing Ltd, 2017. http://dx.doi.org/10.1002/9781405177535.ch5.

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2

Barnes, P. J., and C. P. Page. "Novel Anti-inflammatory Therapies." In Handbook of Experimental Pharmacology, 349–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-09264-4_13.

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Drazen, Jeffrey M. "Anti-Leukotrienes as Novel Anti-Inflammatory Treatments in Asthma." In Advances in Experimental Medicine and Biology, 217–21. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0193-0_33.

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4

Jarman, Michael. "Design of Novel Anti-Endocrine Agents." In New Approaches in Cancer Pharmacology: Drug Design and Development, 47–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77874-2_6.

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5

Abuzzahab, F. S. "Ondansetron: A Novel Anti-anxiety Agent." In New Concepts in Anxiety, 185–89. London: Macmillan Education UK, 1991. http://dx.doi.org/10.1007/978-1-349-11847-2_13.

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6

Rothlein, Robert. "ANTI-ICAM In Inflammatory Disease." In Novel Molecular Approaches to Anti-Inflammatory Therapy, 97–108. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8_10.

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Perretti, Mauro, and Roderick J. Flower. "Anti-Inflammatory Lipocortin-Derived Peptides." In Novel Molecular Approaches to Anti-Inflammatory Therapy, 131–38. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8_13.

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8

Simmons, David. "Individualism and the Anti-Capitalist, Anti-Heroic Figure in American Fiction of the 1960s." In The Anti-Hero in the American Novel, 43–79. New York: Palgrave Macmillan US, 2008. http://dx.doi.org/10.1057/9780230612525_2.

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Fink, M. P. "Ethyl Pyruvate: A Novel Anti-inflammatory Agent." In Intensive Care Medicine, 604–14. New York, NY: Springer New York, 2003. http://dx.doi.org/10.1007/978-1-4757-5548-0_57.

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10

Sankhwar, Shweta, Dhirendra Pandey, and R. A. Khan. "A Novel Anti-phishing Effectiveness Evaluator Model." In Information and Communication Technology for Intelligent Systems (ICTIS 2017) - Volume 2, 610–18. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-63645-0_68.

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Тези доповідей конференцій з теми "Anti-novel"

1

Chen, Tung-Shou, Jeanne Chen, Yuan-Hung Kao, and Tsang-Chou Hsieh. "A Novel Anti-data Mining Technique Based On Hierarchical Anti-clustering (HAC)." In 2008 Eighth International Conference on Intelligent Systems Design and Applications (ISDA). IEEE, 2008. http://dx.doi.org/10.1109/isda.2008.155.

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Tran, Phong, and Thomas J. Webster. "Novel anti-cancer orthopedic materials: Nanostructured selenium." In 2007 IEEE 33rd Annual Northeast Bioengineering Conference. IEEE, 2007. http://dx.doi.org/10.1109/nebc.2007.4413367.

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Azadegan, S., W. Yu, H. Liu, M. Sistani, and S. Acharya. "Novel Anti-forensics Approaches for Smart Phones." In 2012 45th Hawaii International Conference on System Sciences (HICSS). IEEE, 2012. http://dx.doi.org/10.1109/hicss.2012.452.

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Aref, Mohamed A., and Sudharman K. Jayaweera. "A novel cognitive anti-jamming stochastic game." In 2017 Cognitive Communications for Aerospace Applications Workshop (CCAA). IEEE, 2017. http://dx.doi.org/10.1109/ccaaw.2017.8001605.

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Xiong, Ying, and Qiang Liu. "Novel Lorentz Anti-Roll Inertially Stabilized Platform." In 2022 6th International Conference on Robotics, Control and Automation (ICRCA). IEEE, 2022. http://dx.doi.org/10.1109/icrca55033.2022.9828887.

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Yang, Chi-Yea, Yu-Hsin Kao, and Tan-Yi Huang. "A Novel Anti Nano-Silver Particle Bacteria." In 2008 8th IEEE Conference on Nanotechnology (NANO). IEEE, 2008. http://dx.doi.org/10.1109/nano.2008.266.

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Yemelyanov, Alexander, and Irina Budunova. "Abstract 2625: Proteasome inhibitor Bortezomib increases anti-cancer activity of novel anti-inflammatory anti-androgen Compound A." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2625.

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Chung-Liang Chang. "Novel multiplexing technique in anti-jamming GNSS receiver." In 2011 American Control Conference. IEEE, 2011. http://dx.doi.org/10.1109/acc.2011.5990642.

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Murano, Tomomitsu. "A novel anti-collision protocol for RFID systems." In 2007 IEEE Workshop on Automatic Identification Advanced Technologies. IEEE, 2007. http://dx.doi.org/10.1109/autoid.2007.380604.

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Hu, Jianguo, Ke Lin, Deming Wang, Yanyu Ding, and Hongzhou Tan. "A novel anti-collision algorithm for RFID system." In 2010 IEEE International Conference on Rfid-Technology and Applications (RFID-TA). IEEE, 2010. http://dx.doi.org/10.1109/rfid-ta.2010.5529914.

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Звіти організацій з теми "Anti-novel"

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Author, Not Given. Discovery and Development of Novel Anti-Arthritic Agents. Office of Scientific and Technical Information (OSTI), September 2009. http://dx.doi.org/10.2172/971998.

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2

Baskar, Sivasubramanian. Novel Gene Therapy for Enhancing Anti-Tumor Immunity. Fort Belvoir, VA: Defense Technical Information Center, July 1995. http://dx.doi.org/10.21236/ada300057.

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Zhang, Yan. Anibamine and its Analogues as Novel Anti-Prostate Cancer Agents. Fort Belvoir, VA: Defense Technical Information Center, June 2009. http://dx.doi.org/10.21236/ada505201.

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Liu, Xuedong. Largazole as a Novel and Selective Anti-Breast Cancer Agent. Fort Belvoir, VA: Defense Technical Information Center, October 2012. http://dx.doi.org/10.21236/ada569378.

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Phillips, Andrew. Largazole as a Novel and Selective Anti-Breast Cancer Agent. Fort Belvoir, VA: Defense Technical Information Center, October 2012. http://dx.doi.org/10.21236/ada573822.

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Liu, Xuedong. Largazole as a Novel and Selective Anti-Breast Cancer Agent. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada599217.

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Liu, Xuedong. Largazole as a Novel and Selective Anti-Breast Cancer Agent. Fort Belvoir, VA: Defense Technical Information Center, October 2011. http://dx.doi.org/10.21236/ada555744.

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Richards, Talmesha. Polyamine Analogues as Novel Anti-HER Family Agents in Human Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada513832.

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Richards, Talmesha. Polyamine Analogues as Novel Anti-HER Family Agents in Human Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2007. http://dx.doi.org/10.21236/ada477006.

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DeFreest, Lori A., and James A. Bennett. Identification of Cellular Binding Sites for a Novel Human Anti-Breast Cancer Peptide. Fort Belvoir, VA: Defense Technical Information Center, May 2003. http://dx.doi.org/10.21236/ada416487.

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