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Статті в журналах з теми "Allergy Immunological aspects"
Littlewood, J. M. "Allergy. Immunological and Clinical Aspects." Archives of Disease in Childhood 60, no. 3 (March 1, 1985): 292. http://dx.doi.org/10.1136/adc.60.3.292.
Повний текст джерелаGodfrey, R. C. "Allergy: immunological and clinical aspects." British Journal of Diseases of the Chest 79 (January 1985): 409. http://dx.doi.org/10.1016/0007-0971(85)90081-6.
Повний текст джерелаDavid, T. J. "Book Review: Allergy: Immunological and Clinical Aspects." Journal of the Royal Society of Medicine 78, no. 5 (May 1985): 425. http://dx.doi.org/10.1177/014107688507800535.
Повний текст джерелаBochner, B. S., B. J. Undem, and L. M. Lichtenstein. "Immunological Aspects of Allergic Asthma." Annual Review of Immunology 12, no. 1 (April 1994): 295–335. http://dx.doi.org/10.1146/annurev.iy.12.040194.001455.
Повний текст джерелаAhmed, Syed M., Tar-Ching Aw, and Anil Adisesh. "Toxicological and Immunological Aspects of Occupational Latex Allergy." Toxicological Reviews 23, no. 2 (2004): 123–34. http://dx.doi.org/10.2165/00139709-200423020-00005.
Повний текст джерелаRoubey, Robert A. S. "Antiphospholipid antibodies: immunological aspects." Clinical Immunology 112, no. 2 (August 2004): 127–28. http://dx.doi.org/10.1016/j.clim.2004.02.010.
Повний текст джерелаČolić, Miodrag, Sergej Tomić, and Marina Bekić. "Immunological aspects of nanocellulose." Immunology Letters 222 (June 2020): 80–89. http://dx.doi.org/10.1016/j.imlet.2020.04.004.
Повний текст джерелаGarrido-Urbani, S., M. Meguenani, F. Montecucco, and B. A. Imhof. "Immunological aspects of atherosclerosis." Seminars in Immunopathology 36, no. 1 (November 9, 2013): 73–91. http://dx.doi.org/10.1007/s00281-013-0402-8.
Повний текст джерелаCorrigan, Chris J. "Immunological Aspects of Asthma." Clinical Immunotherapeutics 1, no. 1 (January 1994): 31–42. http://dx.doi.org/10.1007/bf03258489.
Повний текст джерелаBárány, Peter, and Ingela Fehrman-Ekholm. "Immunological Aspects of Haemodialysis." Clinical Immunotherapeutics 1, no. 6 (June 1994): 469–80. http://dx.doi.org/10.1007/bf03259039.
Повний текст джерелаДисертації з теми "Allergy Immunological aspects"
See, Sarah Bihui. "Outer membrane protein immunity to Pasteurella pneumotropica and the interaction of allergy." University of Western Australia. School of Paediatrics and Child Health, 2010. http://theses.library.uwa.edu.au/adt-WU2010.0103.
Повний текст джерелаNoakes, Paul Stanton. "The effects of maternal smoking on infant immune development." University of Western Australia. School of Paediatrics and Child Health, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0080.
Повний текст джерелаXiong, Yelin. "Immune modulation of allergic airways disease." Phd thesis, 1998. http://hdl.handle.net/1885/144680.
Повний текст джерелаSawant, Deepali Vijay. "Control of inflammation, helper T cell responses and regulatory T cell function by Bcl6." Thesis, 2014. http://hdl.handle.net/1805/3829.
Повний текст джерелаRegulatory T (Treg) cells represent an important layer of immune-regulation indispensible for curtailing exuberant inflammatory responses and maintaining self-tolerance. Treg cells have translational potential for autoimmunity, inflammation, transplantation and cancer. Therefore, delineating the molecular underpinnings underlying the development, suppressor function and stability of Tregs is particularly warranted. The transcriptional repressor Bcl6 is a critical arbiter of helper T cell fate, promoting the follicular helper (Tfh) lineage while repressing Th1, Th2 and Th17 differentiation. Bcl6-deficient mice develop a spontaneous and severe Th2-type inflammatory disease including myocarditis and pulmonary vasculitis, suggesting a potential role for Bcl6 in Treg cell function. Bcl6-deficient Treg cells are competent in controlling Th1 responses, but fail to control Th2 inflammation in an airway allergen model. Importantly, mice with Bcl6 deleted specifically in the Treg lineage develop severe myocarditis, thus highlighting a critical role for Bcl6 in Treg-mediated control of Th2 inflammation. Bcl6-deficient Tregs display an intrinsic increase in Th2 genes and microRNA-21 (miR-21) expression. MiR-21 is a novel Bcl6 gene target in T cells and ectopic expression of miR-21 directs Th2 differentiation in non-polarized T cells. MiR-21 is up-regulated in mouse models of airway inflammation and also in human patients with eosinophilic esophagitis and asthma. Thus, miR-21 is a clinically relevant biomarker for Th2-type pathologies. Our results define a key function for Bcl6 in repressing Gata3 function and miR-21 expression in Tregs, and provide greater understanding of the control of Th2 inflammatory responses by Treg cells.
"Intracellular signaling mechanisms regulating the mast cell-mediated allergic inflammation." 2007. http://library.cuhk.edu.hk/record=b5893246.
Повний текст джерелаThesis (M.Phil.)--Chinese University of Hong Kong, 2007.
Includes bibliographical references (leaves 120-135).
Abstracts in English and Chinese.
Acknowledgements --- p.i
Abbreviations --- p.iii
Abstract --- p.vi
撮要 --- p.ix
Publications --- p.xi
Table of contents --- p.xiii
Chapter Chapter 1 --- General Introduction
Chapter 1.1 --- Allergic Diseases and Allergic Inflammation --- p.1
Chapter 1.1.1 --- Prevalence of Allergic Diseases --- p.1
Chapter 1.1.2 --- Common Allergic Diseases: Allergic Asthma --- p.1
Chapter 1.1.3 --- Common Allergic Diseases: Atopic Dermatitis --- p.2
Chapter 1.1.4 --- Allergic Inflammation --- p.3
Chapter 1.2 --- The Inflammatory Leukocytes: Mast Cells and Eosinophils --- p.6
Chapter 1.2.1 --- Characteristics of Mast Cells --- p.6
Chapter 1.2.2 --- Mast Cells Distribution --- p.8
Chapter 1.2.3 --- Mast Cells Subtypes --- p.8
Chapter 1.2.4 --- HMC-1 Cells --- p.9
Chapter 1.2.5 --- Characteristics of Eosinophils --- p.12
Chapter 1.3 --- Adhesion Molecules in Allergic Diseases --- p.15
Chapter 1.3.1 --- Adhesion Molecules and Leukocyte Migration --- p.15
Chapter 1.3.2 --- Selectin --- p.17
Chapter 1.3.3 --- Intermolecular Adhesion Molecules --- p.17
Chapter 1.3.4 --- Integrin --- p.18
Chapter 1.4 --- Cytokines and Chemokines in Allergic Diseases --- p.18
Chapter 1.4.1 --- IL-6 --- p.20
Chapter 1.4.2 --- CXCL1 --- p.21
Chapter 1.4.3 --- CXCL8 --- p.21
Chapter 1.4.3 --- CCL2 --- p.22
Chapter 1.5 --- Intercellular Signal Transduction Pathways in Inflammation --- p.24
Chapter 1.5.1 --- RAS-RAF-mitogen-activated Protein Kinases --- p.24
Chapter 1.5.2 --- Janus Kinase/ Signal Transducers and Activators of Transcriptions Pathway --- p.27
Chapter 1.5.3 --- Nuclear Factor-KB Pathway --- p.29
Chapter 1.5.4 --- Phosphoinositide 3-Kinase Pathway --- p.31
Chapter 1.6 --- Aims and Scope of the Study --- p.33
Chapter Chapter 2 --- Materials and Methods
Chapter 2.1 --- Materials --- p.35
Chapter 2.1.1 --- HMC-1 Cell Line --- p.35
Chapter 2.1.2 --- Human Buffer Coat --- p.35
Chapter 2.1.3 --- Human Mast Cell Chymase and TLR ligands --- p.35
Chapter 2.1.4 --- Media and Reagents for Cell Culture --- p.36
Chapter 2.1.5 --- Reagents and Buffers for Purification of Human Eosinophils --- p.37
Chapter 2.1.6 --- Reagents and Buffers for Flow Cytmetry --- p.38
Chapter 2.1.7 --- Reagents and Buffers for Total RNA Extraction --- p.41
Chapter 2.1.8 --- Reagents and Buffers for Reverse Transcription-Polymerase Chain Reaction (RT-PCR) --- p.42
Chapter 2.1.9 --- Reagents and Buffers for Agarose Gel Electrophoresis --- p.45
Chapter 2.1.10 --- Reagents and Buffers for Sodium Dodecyl Sulfate -polyacrylamide Gel Electrophoresis (SDS-PAGE) --- p.46
Chapter 2.1.11 --- Reagents and Buffers for Western Blot Analysis --- p.48
Chapter 2.1.12 --- Chemotactic Migration --- p.51
Chapter 2.1.13 --- Signaling Transduction Inhibitors and Protein Synthesis Inhibitors --- p.51
Chapter 2.2 --- Methods --- p.52
Chapter 2.2.1 --- HMC-1 Cell Cultures --- p.52
Chapter 2.2.2 --- Purification of Buffy Coat Eosinophils by MACS and Eosinophil Culture --- p.52
Chapter 2.2.3 --- Total Cellular RNA Extraction --- p.53
Chapter 2.2.4 --- RT-PCR --- p.54
Chapter 2.2.5 --- Agarose Gel Electrophoresis --- p.55
Chapter 2.2.6 --- Flow Cytometry Analysis --- p.55
Chapter 2.2.7 --- Protein Array Analysis of Cytokine Release --- p.57
Chapter 2.2.8 --- Quantitative Analysis ofCXCLl --- p.58
Chapter 2.2.9 --- Total Protein Extraction --- p.58
Chapter 2.2.10 --- SDS-PAGE --- p.58
Chapter 2.2.11 --- Western Blot Analysis --- p.59
Chapter 2.2.12 --- Chemotactic Migration Analysis --- p.60
Chapter 2.2.13 --- Statistical Analysis --- p.60
Chapter Chapter 3 --- Effects of Mast Cell Derived Chymase on Human Eosinophils and the Signaling Mechanisms: Implication in Allergic Inflammation
Chapter 3.1 --- Introduction --- p.61
Chapter 3.2 --- Results --- p.65
Chapter 3.2.1 --- Effects of Chymase on Eosinophil Survival --- p.65
Chapter 3.2.2 --- Effects of Chymase on the Adhesion Molecule Expression of Eosinophils --- p.68
Chapter 3.2.3 --- Effects of Chymase on the Chemokinetic Properties on Eosinophils --- p.71
Chapter 3.2.4 --- Effects of Chymase on the Release of Chemokines and IL-6 from Eosinophils --- p.73
Chapter 3.2.5 --- Signal Transduction Mechanism Involved in Regulating Chymase-induced Effects on Eosinophils --- p.78
Chapter 3.3 --- Discussion --- p.71
Chapter Chapter 4 --- TLR-mediated Effects and Signal Transduction Mechanism of HMC-1 Cells
Chapter 4.1 --- Introduction --- p.92
Chapter 4.2 --- Results --- p.97
Chapter 4.2.1 --- Expression of Adhesion Molecules on HMC-1 Cells --- p.95
Chapter 4.2.2 --- TLR Expression Profile on HMC-1 Cells --- p.97
Chapter 4.2.3 --- Effects of TLR ligands on HMC-1 Cell Adhesion Molecule Expressions --- p.99
Chapter 4.2.4 --- TLR7-induced Phosphorylation of ERK and Effects of PD98059 on TLR7-induced ERK Phosphorylation --- p.104
Chapter 4.2.5 --- Effect of TLR7 Ligand on HMC-1 Cells Cytokine Release --- p.108
Chapter 4.3 --- Discussion --- p.110
Chapter Chapter 5 --- Conclusions and Future Perspectives
Chapter 5.1 --- Conclusions --- p.115
Chapter 5.2 --- Future Perspectives --- p.117
References --- p.120
Appendix --- p.136
Glosson, Nicole L. "Development and stability of IL-17-secreting T cells." Thesis, 2014. http://hdl.handle.net/1805/5902.
Повний текст джерелаIL-17-producing T cells are critical to the development of pathogen and tumor immunity, but also contribute to the pathology of autoimmune diseases and allergic inflammation. CD8+ (Tc17) and CD4+ (Th17) IL-17-secreting T cells develop in response to a cytokine environment that activates Signal Transducer and Activator of Transcription (STAT) proteins, though the mechanisms underlying Tc17/Th17 development and stability are still unclear. In vivo, Tc17 cells clear vaccinia virus infection and acquire cytotoxic potential, that is independent of IL-17 production and the acquisition of IFN-γ-secreting potential, but partially dependent on Fas ligand, suggesting that Tc17-mediated vaccinia virus clearance is through cell killing independent of an acquired Tc1 phenotype. In contrast, memory Th cells and NKT cells display STAT4-dependent IL-23-induced IL-17 production that correlates with Il23r expression. IL-23 does not activate STAT4 nor do other STAT4-activating cytokines induce Il23r expression in these populations, suggesting a T cell-extrinsic role for STAT4 in mediating IL-23 responsiveness. Although IL-23 is important for the maintenance of IL-17-secreting T cells, it also promotes their instability, often resulting in a pathogenic Th1-like phenotype in vitro and in vivo. In vitro-derived Th17 cells are also flexible when cultured under polarizing conditions that promote Th2 or Th9 differentiation, adopting the respective effector programs, and decreasing IL-17 production. However, in models of allergic airway disease, Th17 cells do not secrete alternative cytokines nor adopt other effector programs, and remain stable IL-17-secretors. In contrast to Th1-biased pro-inflammatory environments that induce Th17 instability in vivo, during allergic inflammatory disease, Th17 cells are comparatively stable, and retain the potential to produce IL-17. Together these data document that the inflammatory environment has distinct effects on the stability of IL-17-secreting T cells in vivo.
Clark, Kristopher. "Eosinophil activation in a mouse model of allergic airways disease." Thesis, 2003. http://hdl.handle.net/1885/148528.
Повний текст джерелаКниги з теми "Allergy Immunological aspects"
Pawankar, Ruby. Allergy frontiers. New York: Springer, 2009.
Знайти повний текст джерелаInternational Conference on Immunopharmacology (4th 1988 Osaka, Japan). Abstracts of workshop presentations. Oxford: Pergamon Press, 1988.
Знайти повний текст джерелаPawankar, Ruby. Allergy Frontiers: Diagnosis and Health Economics. Tokyo: Springer Japan, 2009.
Знайти повний текст джерела1947-, Moqbel Redwan, ed. Allergy and immunity to helminths: Common mechanisms or divergent pathways? London: Taylor & Francis, 1992.
Знайти повний текст джерелаAllergy and immunology of the eye. 2nd ed. New York: Raven Press, 1993.
Знайти повний текст джерелаCh'oe, Min-hŭi. Gutpai at'op'i. Sŏul-si: 21-segi Buksŭ, 2009.
Знайти повний текст джерелаH, Dunn Denise, ed. Allergies and autism. New York: Nova Science, 2010.
Знайти повний текст джерелаDochniak, Michael J. Allergies and autism. Hauppauge, N.Y: Nova Science, 2009.
Знайти повний текст джерелаDochniak, Michael J. Allergies and autism. Hauppauge, N.Y: Nova Science, 2009.
Знайти повний текст джерелаA, Clark D., and Croy B. A, eds. Reproductive immunology 1986: Proceedings of the 3rd International Congress of Reproductive Immunology held in Toronto, Canada, 1-5 July 1986. Amsterdam: Elsevier Science Publishers, 1986.
Знайти повний текст джерелаЧастини книг з теми "Allergy Immunological aspects"
Scheynius, Annika. "Immunological Aspects." In Allergic Contact Dermatitis, 4–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80331-4_2.
Повний текст джерелаNally, F. F., and J. J. H. Gilkes. "Mucocutaneous Allergic Reactions." In Immunological Aspects of Oral Diseases, 257–74. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4167-0_12.
Повний текст джерелаElsner, Jörn, and Alexander Kapp. "Immunological aspects of allergic inflammation: eosinophils." In Immunology and Drug Therapy of Allergic Skin Diseases, 49–71. Basel: Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8464-8_4.
Повний текст джерелаDubois, Gerald R., Paul J. Baselmans, and Geert C. Mudde. "Immunological aspects of allergic inflammation: IgE regulation." In Immunology and Drug Therapy of Allergic Skin Diseases, 15–28. Basel: Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8464-8_2.
Повний текст джерелаBrauer, David Lawrence, and Katharine Margaret Woessner. "Non-pharmacologic Aspects of Management: “Asthma and Allergic and Immunologic Diseases During Pregnancy – A Guide to Management”." In Asthma, Allergic and Immunologic Diseases During Pregnancy, 1–14. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-03395-8_1.
Повний текст джерелаMartin, R. "Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis and their application for new therapeutic strategies." In Advances in Research on Neurodegeneration, 53–67. Vienna: Springer Vienna, 1997. http://dx.doi.org/10.1007/978-3-7091-6844-8_6.
Повний текст джерелаAalberse, Rob C., and Paolo M. Matricardi. "Immunological Aspects of the Atopic March." In Allergy, Immunity and Tolerance in Early Childhood, 19–31. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-420226-9.00002-4.
Повний текст джерела"Food Allergy: Immunological Aspects and Approaches to Safety Assessment." In Immunotoxicology and Immunopharmacology, 631–46. CRC Press, 2006. http://dx.doi.org/10.1201/9781420005448-50.
Повний текст джерелаLorenz, Anne-Regine, Stephan Scheurer, and Stefan Vieths. "Food Allergens: Molecular and Immunological Aspects, Allergen Databases and Cross-Reactivity." In Food Allergy: Molecular Basis and Clinical Practice, 18–29. S. Karger AG, 2015. http://dx.doi.org/10.1159/000371647.
Повний текст джерелаMa, Songhui. "Immunologic Aspects of Rhinosinusitis." In Sataloff’s Comprehensive Textbook of Otolaryngology: Head and Neck Surgery (Rhinology/Allergy and Immunology) -Volume 2, 391. Jaypee Brothers Medical Publishers (P) Ltd., 2016. http://dx.doi.org/10.5005/jp/books/12714_27.
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