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Статті в журналах з теми "Allele variances"
Wang, Jinliang. "An Estimator for Pairwise Relatedness Using Molecular Markers." Genetics 160, no. 3 (March 1, 2002): 1203–15. http://dx.doi.org/10.1093/genetics/160.3.1203.
Повний текст джерелаZeng, Z. B., D. Houle, and C. C. Cockerham. "How informative is Wright's estimator of the number of genes affecting a quantitative character?" Genetics 126, no. 1 (September 1, 1990): 235–47. http://dx.doi.org/10.1093/genetics/126.1.235.
Повний текст джерелаYi, Nengjun, and Shizhong Xu. "A Random Model Approach to Mapping Quantitative Trait Loci for Complex Binary Traits in Outbred Populations." Genetics 153, no. 2 (October 1, 1999): 1029–40. http://dx.doi.org/10.1093/genetics/153.2.1029.
Повний текст джерелаQing-Quan, Chen, Yu Si-Bin, Li Chun-Hai, and Mou Tong-Min. "QTL identification for seed setting rate of rice in various environments." Chinese Journal of Agricultural Biotechnology 4, no. 3 (December 2007): 239–45. http://dx.doi.org/10.1017/s1479236207001970.
Повний текст джерелаZeng, Z. B., and C. C. Cockerham. "Variance of neutral genetic variances within and between populations for a quantitative character." Genetics 129, no. 2 (October 1, 1991): 535–53. http://dx.doi.org/10.1093/genetics/129.2.535.
Повний текст джерелаEasteal, Simon. "THE ECOLOGICAL GENETICS OF INTRODUCED POPULATIONS OF THE GIANT TOAD BUFO MARINUS. II. EFFECTIVE POPULATION SIZE." Genetics 110, no. 1 (May 1, 1985): 107–22. http://dx.doi.org/10.1093/genetics/110.1.107.
Повний текст джерелаRuzzante, Daniel E. "A comparison of several measures of genetic distance and population structure with microsatellite data: bias and sampling variance." Canadian Journal of Fisheries and Aquatic Sciences 55, no. 1 (January 1, 1998): 1–14. http://dx.doi.org/10.1139/f97-203.
Повний текст джерелаWensch-Dorendorf, M., N. Mielenz, E. Groeneveld, M. Kovac, and L. Schüler. "Varianzkomponentenschätzung unter Berücksichtigung von Dominanz an simulierten Reinzuchtlinien." Archives Animal Breeding 47, no. 4 (October 10, 2004): 387–95. http://dx.doi.org/10.5194/aab-47-387-2004.
Повний текст джерелаJakse, Jernej, Zlatko Satovic, and Branka Javornik. "Microsatellite variability among wild and cultivated hops (Humulus lupulus L.)." Genome 47, no. 5 (October 1, 2004): 889–99. http://dx.doi.org/10.1139/g04-054.
Повний текст джерелаLynch, Michael, and Wei-Chin Ho. "The Limits to Estimating Population-Genetic Parameters with Temporal Data." Genome Biology and Evolution 12, no. 4 (March 29, 2020): 443–55. http://dx.doi.org/10.1093/gbe/evaa056.
Повний текст джерелаДисертації з теми "Allele variances"
Hummel, Matthew Aaron. "Dapsone activation of CYP2C9 allelic variants." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=2767.
Повний текст джерелаTitle from document title page. Document formatted into pages; contains vi, 42 p. : ill. Includes abstract. Includes bibliographical references (p. 35-42).
Milani, Lili. "Gene Expression in Cancer Cells : Detection of Splice Variants, Allele-specific Expression and DNA Methylation." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-99067.
Повний текст джерелаMakambwa, Edson. "The role of warfarin pharmacogenomics on the time it takes to reach stable therapeutic International Normalized Ratio (INR) and on warfarin dose required to maintain stable therapeutic INR in Black African and Mixed Ancestry South Africans: a focus on CYP2C9 and VKORC1." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31178.
Повний текст джерелаCid, Nuria Alonso Lopez. "AVALIAÇÃO DE POLIMORFISMOS DA CYP3A5 EM INDIVÍDUOS DA REGIÃO CENTRO-OESTE DO BRASIL." Pontifícia Universidade Católica de Goiás, 2016. http://localhost:8080/tede/handle/tede/2410.
Повний текст джерелаThe advances in Anesthesiology took place at the same time as the development of drugs that ensured greater control over pain, patient comfort, and safety during surgical anesthetic procedures. Pharmacogenetics is the science that enables enhanced healthcare, by understanding the genetic variations that may affect the different responses to treatments. CYP3A are the most important enzymes involved in the metabolism of drugs prescribed in clinical practice, showing extensive genetic variability in their expression. CYP3A5 presents the highest number of functional variants, with significant differences in the frequencies observed among different population groups around the world and in Brazil. This study aimed and at assessing the frequency of CYP3A5*3 and CYP3A5*6 genotypic and allelic variants and to estimate the metabolizing profile according to these variants, as well as any potential implications on adverse events with drugs used in anesthesia. The sample used for this study included 166 subjects users of the Laboratório da Área de Saúde da PUCGoiás (PUC Healthcare Laboratory city of Goiás). They were all born in the Brazilian Midwest, over 18 years of age, and from both genders. The blood samples were obtained from each individual and genotyped for CYP3A5*3, A>G (rs 776746) and CYP3A5*6, G>A (rs 10264272) by real time Polymerase Chain Reaction using TaqMan assays. Data analysis of the allelic frequency was conducted by calculating the percentage for the established groups, according to color or race, compared to the total sample. In individuals from the Brazilian Midwest, assessed in this study, the frequency of the allelic variant CYP3A5*3 was 40% and 2% for CYP3A5*6. The frequency observed for the CYP3A5*3 allelic variant in subjects from the Midwest was lower than that from other Brazilian studies and also lower than the frequencies observed in Europeans and Asians, however, they were similar to the frequency seen in populations from East and West Africa. The frequency of the CYP3A5*6 allelic variant, in this study, was higher than that found in European studies and similar of the subjects in the North of Africa. Based on the results, one may infer that 72% would be poor metabolizers. The higher frequency of the poor metabolizer profile shows that there is potential for a greater occurrence of adverse events when using drugs metabolized by CYP3A5 in this population from the Brazilian Midwest.
O progresso da Anestesiologia junto com o desenvolvimento de drogas garantiram maior controle da dor, conforto ao paciente e segurança durante o ato anestésicocirúrgico. A Farmacogenética é uma ciência que permite a melhora da assistência à saúde, por meio do conhecimento das variações genéticas que podem estar envolvidas com as diferenças na resposta terapêutica. As CYP3A são as enzimas mais importantes envolvidas com o metabolismo de drogas prescritas na prática clínica, apresentando grande variabilidade genética na sua expressão. A CYP3A5 é a forma que apresenta mais variantes funcionais e com diferenças expressivas nas frequências observadas em diferentes grupos populacionais do mundo. Este estudo teve como objetivo avaliar a frequência das variantes genotípicas e alélicas do CYP3A5*3 e CYP3A5*6 e inferir sobre o perfil metabolizador dos indivíduos em função destas variantes em relação a drogas usadas em anestesia. O grupo avaliado incluiu 166 indivíduos usuários do Laboratório da Área de Saúde da PUCGoiás, nascidos na região Centro-Oeste do Brasil, maiores de 18 anos e de ambos os sexos. As amostras de sangue foram obtidas de cada indivíduo e genotipados para CYP3A5*3, A>G (rs 776746) and CYP3A5*6, G>A (rs 10264272) por Reação em Cadeia de Polimerase usando sondas TaqMan. A análise dos dados das frequências alélicas foi realizada através do cálculo das porcentagens para os grupos estabelecidos, segundo a cor ou raça, em relação a amostra total. Nos indivíduos da região Centro-Oeste do Brasil avaliados neste estudo, a frequência da variante alélica CYP3A5*3 foi de 40% e da CYP3A5*6 foi de 2%. A frequência observada para a variante alélica CYP3A5*3 em indivíduos da região Centro-Oeste foi menor que a de outros estudos brasileiros e também menor que as frequências verificadas em europeus e asiáticos, porém similar à observada na população do leste e oeste da África. A frequência da variante alélica CYP3A5*6, neste estudo, foi maior que a encontrada em estudos europeus e com valores mais próximos daqueles observados no norte da África. Com base nos resultados obtidos da amostra pode-se inferir que 72% dos indivíduos seriam fracos metabolizadores. A maior frequência do perfil de fraco metabolizador mostra que existe potencial de maior ocorrência de eventos adversos no uso de fármacos metabolizados pela CYP3A5 nesta população da região Centro-Oeste do Brasil.
Yang, Su jeong. "Biochemical and biophysical characterisation of allelic variants of ovine prion protein." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611255.
Повний текст джерелаWalton, Esther, Daniel Geisler, Johannes Hass, Jingyu Liu, Jessica Turner, Anastasia Yendiki, Michael N. Smolka, et al. "The Impact of Genome-Wide Supported Schizophrenia Risk Variants in the Neurogranin Gene on Brain Structure and Function." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-132122.
Повний текст джерелаJin, Huilin. "Mechanisms of osteoporosis associated with common allelic variants of the COL1A1 gene." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/29182.
Повний текст джерелаAlbers, Patrick K. "Rare and low-frequency variants and predisposition to complex disease." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:2d569297-5d2a-49c8-a1ca-32a978aec49d.
Повний текст джерелаGréard, Camille. "La détection des variants alléliques comme voie d'amélioration génétique des plantes fourragères : exemple de la luzerne." Thesis, Poitiers, 2019. http://www.theses.fr/2019POIT2261.
Повний текст джерелаLucerne (Medicago sativa) is an autotetraploid forage legume, whose breeding could beneficiate from allele mining. This strategy is based on the natural diversity and consists in seeking alleles with a potential effect on the phenotype. The interest of this approach was evaluated by studying five genes of agronomic interest: CAD1 and CCoaOMT (digestibility), CONSTANS-like (forage yield), NHX1 (salt tolerance) and WXP1 (drought tolerance). The diversity of these five genes was evaluated by sequencing 387 genotypes of cultivated accessions and 20 genotypes of wild accessions. The results confirmed a bottleneck during lucerne domestication and selection. CONSTANS-like and WXP1 were very variable whereas CAD1, CCoaOMT and NHX1 contained very few variants. Variants with a potential strong impact on the phenotype were identified in conserved parts of protein sequence within the Faboideae. The impact on phenotype was studied for two mutations of the CONSTANS-like gene: constans-634, causing a premature stop codon and constans-4111, located in a conserved region of the gene. Genotypes carrying one to three doses of the mutations (AAAB, AABB and ABBB) were polycrossed in order to obtain offsprings with every allele combination (AAAA, AAAB, AABB, ABBB and BBBB). KASPar markers were developed to determine the mutation doses in offspring progeny. No homozygous genotype was found for constans-634 in the 1505 offspring progeny. This mutation induced a premature flowering of three days for the genotypes carrying three doses of the mutation. The mutation constans-4111 induced an additive effect on stem height and the homozygous genotypes without the variant where on average 11.8 cm shorter than homozygous genotypes carrying three or four doses of the variant. The application of allele mining strategy in plant schemes of heterozygous autotetraploid species was discussed
Johnson, Andrew Danner. "Search for functional alleles in the human genome with focus on cardiovascular disease candidate genes." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1187018497.
Повний текст джерелаКниги з теми "Allele variances"
Walsh, Bruce, and Michael Lynch. Short-term Changes in the Variance: 1. Changes in the Additive Variance. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198830870.003.0016.
Повний текст джерелаWalsh, Bruce, and Michael Lynch. Analysis of Short-term Selection Experiments: 2. Mixed-model and Bayesian Approaches. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198830870.003.0019.
Повний текст джерелаApolipoprotein E (ApoE) allelic variants: Involvement in type 2 dibetes. Ottawa: National Library of Canada, 2003.
Знайти повний текст джерелаHaiman, Christopher, and David J. Hunter. Genetic Epidemiology of Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0004.
Повний текст джерелаWalsh, Bruce, and Michael Lynch. The Infinitesimal Model and Its Extensions. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198830870.003.0024.
Повний текст джерелаCazeneuve, Cécile, and Alexandra Durr. Genetic and Molecular Studies. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0006.
Повний текст джерелаHegel, Georg Wilhelm Friedrich. Vorlesungen über die Philosophie der Religion und Vorlesungen über die Beweise vom Dasein Gottes II. Felix Meiner Verlag, 2021. http://dx.doi.org/10.28937/978-3-7873-3735-4.
Повний текст джерелаBarr, Christina S. Gene-by-Environment Interactions in Primates. Edited by Turhan Canli. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199753888.013.006.
Повний текст джерелаCollin, Peter, Gert Bender, Stefan Ruppert, Margrit Seckelmann, and Michael Stolleis, eds. Selbstregulierung im 19. Jahrhundert – zwischen Autonomie und Steuerungsansprüchen. Klostermann, 2013. http://dx.doi.org/10.5771/9783465141228.
Повний текст джерелаJohansson, Ann-Sofie. Exploring the Functional Plasticity of Human Glutathione Transferases: Allelic Variants, Novel Isoenzyme & Enzyme Redesign (Comprehensive Summaries of ... the Faculty of Science and Technology, 695). Uppsala Universitet, 2002.
Знайти повний текст джерелаЧастини книг з теми "Allele variances"
Lefferts, Juliet W., Vera Boersma, Marne C. Hagemeijer, Karima Hajo, Jeffrey M. Beekman, and Erik Splinter. "Targeted Locus Amplification and Haplotyping." In Methods in Molecular Biology, 31–48. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2819-5_2.
Повний текст джерелаHakomori, Sen-Itiroh. "Histoblood Group A Variants, O Variants, and Their Alleles." In Handbook of Glycosyltransferases and Related Genes, 189–96. Tokyo: Springer Japan, 2002. http://dx.doi.org/10.1007/978-4-431-67877-9_25.
Повний текст джерелаAbraham, Jashan P., Dominic J. Barker, James Robinson, Giuseppe Maccari, and Steven G. E. Marsh. "The IPD Databases: Cataloguing and Understanding Allele Variants." In Methods in Molecular Biology, 31–48. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8546-3_3.
Повний текст джерелаHakomori, Sen-itiroh, and Monica Palcic. "Histo-Blood Group A Variants, O Variants, and Their Alleles." In Handbook of Glycosyltransferases and Related Genes, 479–93. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54240-7_159.
Повний текст джерелаBelt, Peter B. G. M., Alex Bossers, Bram E. C. Schreuder, and Mari A. Smits. "PrP Allelic Variants Associated with Natural Scrapie." In Bovine Spongiform Encephalopathy, 294–305. New York, NY: Springer New York, 1996. http://dx.doi.org/10.1007/978-1-4612-2406-8_21.
Повний текст джерелаSerrano, Ezequiel, Pablo G. Sanz, and Francisco J. Barrantes. "The Impact of Apolipoprotein E Allelic Variants on Alzheimer’s Disease." In Psychiatry and Neuroscience Update, 397–418. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-61721-9_29.
Повний текст джерелаGeng, Yu, Zhongmeng Zhao, Jing Xu, Ruoyu Liu, Yi Huang, Xuanping Zhang, Xiao Xiao, Maomao, and Jiayin Wang. "Identifying Heterogeneity Patterns of Allelic Imbalance on Germline Variants to Infer Clonal Architecture." In Intelligent Computing Theories and Application, 286–97. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-63312-1_26.
Повний текст джерелаBrammli-Greenberg, Shuli, Inon Buda, and Yoram Weiss. "Stationäre Versorgung und Patientensteuerung während der Covid-19-Pandemie in Israel." In Krankenhaus-Report 2022, 235–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-64685-4_13.
Повний текст джерелаLuu, Alice, Brian C. Foster, Kristina L. McIntyre, Teresa W. Tam, and John T. Arnason. "Pharmacogenetics in Potential Herb–Drug Interactions: Effects of Ginseng on CYP3A4 and CYP2C9 Allelic Variants." In The Biological Activity of Phytochemicals, 59–65. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7299-6_5.
Повний текст джерелаKrüger, Timmo. "Mehr Fortschritt wagen? Eine essayistische Kritik der Wette auf grünes Wachstum." In Soziale Bewegung und Protest, 63–80. Bielefeld, Germany: transcript Verlag, 2022. http://dx.doi.org/10.14361/9783839463000-004.
Повний текст джерелаТези доповідей конференцій з теми "Allele variances"
Makey, T. V., and P. M. Marozik. "GENETIC FACTORS OF PREPOSITION TO BONE FRACTURES IN ATHLETES." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute, 2021. http://dx.doi.org/10.46646/sakh-2021-1-287-290.
Повний текст джерела"AD ASTRA: the database of Allelic Dosage-corrected Allele-Specific TRAnscription factor binding suggests causal regulatory sequence variants of pathologies." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-001.
Повний текст джерелаElrayess, Mohamed, Fatima Al-Khelaifi, Noha Yousri, and Omar Al-Bagha. "Genome-Wide Association study Identifies a Novel Association Between a Cardiovascular Gene Polymorphism and Superior Athletic Performance." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0111.
Повний текст джерелаSmatti, Maria K., Yasser Al-Sarraj, Omar Albagha, and Hadi M. Yassine. "Host Genetic Variants Potentially Associated with SARS-Cov-2: A Multi-Population Analysis." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0298.
Повний текст джерела"Complex alleles of splicing variants in Mendelian diseases." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-246.
Повний текст джерелаAffenzeller, Michael, Stefan Wagner, Stephan Winkler, and Andreas Beham. "Analysis of the dynamics of allele distribution for some selected GA-variants." In 2010 IEEE 14th International Conference on Intelligent Engineering Systems. IEEE, 2010. http://dx.doi.org/10.1109/ines.2010.5483852.
Повний текст джерелаLee, Joyce, Andy Wing Chun PANG, Caspar Groß, Jakob Admard, Elena Buena-Atienza, Stephan Ossowski, Thomas Anantharaman, Mark Oldakowski, Sven Bocklandt, and Alex Hastie. "Abstract 1329: Identifying low allele frequency somatic variants using the Saphyr System." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-1329.
Повний текст джерелаSmatti, Maria Khalid, Yasser Al-Sarraj, Omar Albagha, and Hadi Yassine. "Genetic Susceptibility to Infectious Diseases in the Qatari Population." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0092.
Повний текст джерелаAlexiadis, Vassilios, Tim Watanaskul, Karena Kosco, and Lyle Arnold. "Abstract 3198: The CEE-Selector Assay: A tool for the identification of rare allele variants." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3198.
Повний текст джерелаde Oliveira Junior, G. A., M. Spehar, F. S. Schenkel, C. F. Baes, and G. Gorjanc. "198. Long-term changes in genetic mean and genic variance and underlying allele frequencies in breeding programmes." In World Congress on Genetics Applied to Livestock Production. The Netherlands: Wageningen Academic Publishers, 2022. http://dx.doi.org/10.3920/978-90-8686-940-4_198.
Повний текст джерелаЗвіти організацій з теми "Allele variances"
Brayton, Kelly A., Varda Shkap, Guy H. Palmer, Wendy C. Brown, and Thea Molad. Control of Bovine Anaplasmosis: Protective Capacity of the MSP2 Allelic Repertoire. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7699838.bard.
Повний текст джерелаDöring, Thomas. Öffentliche Verschuldung (finanz-)psychologisch betrachtet. Sonderforschungsgruppe Institutionenanalyse, 2019. http://dx.doi.org/10.46850/sofia.9783941627734.
Повний текст джерелаWeller, Joel I., Derek M. Bickhart, Micha Ron, Eyal Seroussi, George Liu, and George R. Wiggans. Determination of actual polymorphisms responsible for economic trait variation in dairy cattle. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600017.bard.
Повний текст джерелаSela, Hanan, Eduard Akhunov, and Brian J. Steffenson. Population genomics, linkage disequilibrium and association mapping of stripe rust resistance genes in wild emmer wheat, Triticum turgidum ssp. dicoccoides. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7598170.bard.
Повний текст джерелаBennett, Alan B., Arthur A. Schaffer, Ilan Levin, Marina Petreikov, and Adi Doron-Faigenboim. Manipulating fruit chloroplasts as a strategy to improve fruit quality. United States Department of Agriculture, January 2013. http://dx.doi.org/10.32747/2013.7598148.bard.
Повний текст джерелаChamovitz, Daniel A., and Albrecht G. Von Arnim. eIF3 Complexes and the eIF3e Subunit in Arabidopsis Development and Translation Initiation. United States Department of Agriculture, September 2009. http://dx.doi.org/10.32747/2009.7696545.bard.
Повний текст джерелаHansen, Peter J., Zvi Roth, and Jeremy J. Block. Improving oocyte competence in dairy cows exposed to heat stress. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7598163.bard.
Повний текст джерела