Готові списки джерел за темами / Aging resistant

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Автор: Grafiati
Опубліковано: 14 березня 2023

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Статті в журналах з теми "Aging resistant"

1

Chen, Tao Ping, Biao Qiu, Na Wang, and Ru He. "Atomic Force Microscope Manifestation of Heat-Resistant Polymer Thermal Stability." Advanced Materials Research 1073-1076 (December 2014): 2267–71. http://dx.doi.org/10.4028/www.scientific.net/amr.1073-1076.2267.

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Aimed at BH heat-resistant polymer, 4500mg/L solution is compounded by oilfield sewage, and then diluted into 1500mg/L solution by oilfield sewage again under room temperature, aging in the constant temperature box of 95°C finally. Test slides are made of different aging time BH heat-resistance polymer solution, whose thermal stability is manifested by atomic force microscope. Results show the aggregation degree of BH heat-resistant polymer solution are different after aging for 30d, 60d, 90d under 95°C. They gather largely before aging, are into a loose branch distribution. After aging for 30d, their aggregation degree declines, branch length becomes shorter. After aging for 60d, their aggregation status change greatly, are into "╫╫" shape comb distribution. After aging for 90d, they gather into about 10μm in diameter short fat wafer, and are not easy to expand.
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Bleszynski, Monika, and Maciej Kumosa. "Aging resistant TiO2/silicone rubber composites." Composites Science and Technology 164 (August 2018): 74–81. http://dx.doi.org/10.1016/j.compscitech.2018.05.035.

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3

Shen, Quanjun, Shijie Ma, Yaohui Yang, Liang Fan, Yongzhen Li, and Pinhui Zhao. "Preparation and Performance Test of UV Resistant Composite-Modified Asphalt." Coatings 13, no. 2 (January 19, 2023): 239. http://dx.doi.org/10.3390/coatings13020239.

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Ultraviolet radiation is the main cause of degradation in asphalt pavement. To improve the performance of the pavement used in the strong ultraviolet (UV) region of the western plateau, China, this study explores the effects of adding nano-montmorillonite and carbon black to SBS-modified asphalt. Through conventional index detection, dynamic shear rheological tests, low-temperature bending creep tests, and UV aging tests, the high- and low-temperature performance, fatigue performance, UV aging resistance, and other aspects of the asphalt were studied. Various performance and price factors were considered in the optimization of various UV resistant composite-modified asphalt formulas. Increasing the contents of nano-montmorillonite and carbon black increases the high-temperature performance and the UV aging resistance but reduces the low-temperature and fatigue performance of asphalt; hence, their total content should be limited to < 4%. Nano-montmorillonite has a better high-temperature performance and UV aging resistance than carbon black and is also less favorable to low-temperature and fatigue performance. Hence, it is recommended that its content not exceed 3%. UV resistant composite-modified asphalt has obvious advantages in high-temperature performance and UV aging resistance compared with conventional SBS-modified asphalt, and its low-temperature performance meets the use requirements of the strong-UV areas in the western plateau.
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4

Warman, Dwina Juliana, Huijuan Jia, and Hisanori Kato. "The Potential Roles of Probiotics, Resistant Starch, and Resistant Proteins in Ameliorating Inflammation during Aging (Inflammaging)." Nutrients 14, no. 4 (February 10, 2022): 747. http://dx.doi.org/10.3390/nu14040747.

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Aging is typically accompanied by biological and physiological changes that alter cellular functions. Two of the most predominant phenomena in aging include chronic low-grade inflammation (inflammaging) and changes in the gut microbiota composition (dysbiosis). Although a direct causal relationship has not been established, many studies have reported significant reductions in inflammation during aging through well-maintained gut health and microbial balance. Prebiotics and probiotics are known to support gut health and can be easily incorporated into the daily diet. Unfortunately, few studies specifically focus on their significance in reducing inflammation during aging. Therefore, this review summarizes the scientific evidence of the potential roles of probiotics and two types of prebiotics, resistant starch and resistant proteins, in later age. Studies have demonstrated that the oral consumption of bacteria that may contribute to anti-inflammatory response, such as Bifidobacterium spp., Akkermansia munichipilla, and Faecalis praunitzii, contributes significantly to the suppression of pro-inflammatory markers in elderly humans and aged animals. Colonic fermentation of resistant starch and proteins also demonstrates anti-inflammatory activity owing to the production of butyrate and an improvement in the gut microbiota composition. Collectively, probiotics, resistant starch, and resistant proteins have the potential to promote healthy aging.
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Wang, Yongqiang, Zhuo Zeng, Meng Gao, and Ziye Huang. "Hygrothermal Aging Characteristics of Silicone-Modified Aging-Resistant Epoxy Resin Insulating Material." Polymers 13, no. 13 (June 29, 2021): 2145. http://dx.doi.org/10.3390/polym13132145.

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To study the improvement effect of silicone materials on the hygrothermal resistance of epoxy resin and the aging mechanism of silicone-modified insulation materials under hygrothermal conditions, diphenylsilanediol was added to epoxy resin as a modifier in various quantities to synthesize silicone-modified epoxy resin, and a hygrothermal aging test was carried out. Water sorption, surface contact angles and dielectric properties of the insulation material were measured, and scanning electron microscope (SEM), Fourier-transform infrared spectrometry (FT-IR) and frequency domain spectroscopy (FDS) were used to analyze the results. The results showed that under 10 wt%, the silicone-modified insulation materials exhibited lower absorption rate and better dielectric properties, including lower dissipation factors and lower dielectric constant during the hygrothermal aging process, while epoxy resin modified with excessive silicone material tend to show worse dielectric performance. Closer analysis found that diphenylsilanediol decreases the size of the cracks within the material during hygrothermal aging, indicating that cracks generated during the hygrothermal aging process may be the reason for the worse dielectric performance, and diphenylsilanediol improves the hygrothermal aging resistance mainly by slowing down the generation and growth rate of cracks. FT-IR results confirmed the existence of hydrolysis and found that the rate of hydrolysis does not change with the content of diphenylsilanediol. FDS results also indicated that modified materials contain less dipoles after hygrothermal aging.
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6

Tecer, Hicran, Emine Acer, Harun Erol, and Mehmet Gündüz. "Effect of Aging on Conductivity of Heat Resistant Overhead Line Conductors." Materials Science Forum 765 (July 2013): 783–87. http://dx.doi.org/10.4028/www.scientific.net/msf.765.783.

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Different kinds of Al and Al alloys are used for all bare overhead energy transmission lines. In the present work, the effect of heat treatments on the conductivity of Al-0.25wt.%Zr alloy has been investigated. Al-0.25wt.%Zr samples were prepared in cold graphite crucibles by using a vacuum furnace and a continuous casting line. The samples were aged isothermally and isochronally in muffle and tube furnaces. Aging was carried out at a wide range of temperatures (350-600 °C) at constant aging times (75 h, 100 h) and a wide range of aging times (25-500 h) at constant temperatures (425 °C, 450 °C). According to the experimental results, conductivities of aged samples increase up to a certain aging temperature and aging time and reach peak values, then decrease with increasing aging temperature and aging time.
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7

ZHU, Shi-Yang. "Genetic analysis on aging-resistant in rice seed." Hereditas (Beijing) 30, no. 2 (February 10, 2008): 217–24. http://dx.doi.org/10.3724/sp.j.1005.2008.00217.

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Stern, Matthew M., and Jackie R. Bickenbach. "Epidermal stem cells are resistant to cellular aging." Aging Cell 6, no. 4 (August 2007): 439–52. http://dx.doi.org/10.1111/j.1474-9726.2007.00318.x.

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9

Bartke, Andrzej, Liou Y. Sun, and Valter Longo. "Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity." Physiological Reviews 93, no. 2 (April 2013): 571–98. http://dx.doi.org/10.1152/physrev.00006.2012.

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Growth hormone (GH) is a key determinant of postnatal growth and plays an important role in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling delays aging and remarkably extends longevity in laboratory mice. In GH-deficient and GH-resistant animals, the “healthspan” is also extended with delays in cognitive decline and in the onset of age-related disease. The role of hormones homologous to insulin-like growth factor (IGF, an important mediator of GH actions) in the control of aging and lifespan is evolutionarily conserved from worms to mammals with some homologies extending to unicellular yeast. The combination of reduced GH, IGF-I, and insulin signaling likely contributes to extended longevity in GH or GH receptor-deficient organisms. Diminutive body size and reduced fecundity of GH-deficient and GH-resistant mice can be viewed as trade-offs for extended longevity. Mechanisms responsible for delayed aging of GH-related mutants include enhanced stress resistance and xenobiotic metabolism, reduced inflammation, improved insulin signaling, and various metabolic adjustments. Pathological excess of GH reduces life expectancy in men as well as in mice, and GH resistance or deficiency provides protection from major age-related diseases, including diabetes and cancer, in both species. However, there is yet no evidence of increased longevity in GH-resistant or GH-deficient humans, possibly due to non-age-related deaths. Results obtained in GH-related mutant mice provide striking examples of mutations of a single gene delaying aging, reducing age-related disease, and extending lifespan in a mammal and providing novel experimental systems for the study of mechanisms of aging.
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Xu, Liang, Yi He, Shaohua Ma, Li Hui, Yaoxiong Jia, and Yiming Tu. "Effects of aging process and testing temperature on the open-hole compressive properties of a carbon fiber composite." High Performance Polymers 32, no. 6 (January 8, 2020): 693–701. http://dx.doi.org/10.1177/0954008319897291.

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The properties of T800 carbon fiber–epoxy composite specimens with a hole were studied in terms of mass change, scanning electron microscopy, glass transition temperature ( T g), heat-resistant temperature, Fourier-transform infrared (FTIR) spectroscopy, open-hole compressive strength at different temperatures, and stereomicroscopic observations after being subjected to hygrothermal aging and thermal-oxidative aging processes. FTIR spectra indicated that after hygrothermal aging at 70°C and 85% relative humidity (RH), chemical aging did not occur, whereas after thermal-oxidative aging at 190°C, the specimens exhibited chemical aging. The unaged specimens had a T g of 229°C and an extreme heat-resistant temperature T gmod of 184°C; after hygrothermal aging, the specimens had a T g and T gmod of 207°C and 143°C, respectively; and after thermal-oxidative aging, the specimens had a T g and T gmod of 252°C and 215°C, respectively. The effects of temperature on open-hole compressive strength were evaluated at room temperature of 23°C, 50°C, 100°C, 150°C, and 200°C. The compressive strengths of the specimens decreased after aging and with the increasing test temperature. At the highest test temperature, the unaged specimens, hygrothermal-aged, and thermal-oxidative-aged specimens retained over 73.7%, 65.5%, and 67.9%, respectively, of their compressive strength. Thus, the T800 carbon fiber–epoxy composite evaluated in this study exhibited good resistance to the effects of aging and high temperature. These results should be beneficial to the understanding of the long-term performance of composites.
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Дисертації з теми "Aging resistant"

1

Parthasarathy, Krupa. "Aging Analysis and Aging-Resistant Design for Low-Power Circuits." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1415615574.

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2

Fox, Bronwyn Louise. "The manufacture, characterization and aging of novel high temperature carbon fibre composites." View thesis entry in Australian Digital Theses Program, 2001. http://thesis.anu.edu.au/public/adt-ANU20011207.114246/index.html.

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3

Nakamura, Yusuke, Hiroshi Inano, Satoshi Hiroshima, Tatsuya Hirose, Masahiro Hamaguchi, and Hitoshi Okubo. "Partial Discharge Resistant Aging Mechanism of Nanocomposite Enamel Wires under Repetitive Surge Voltage Condition." IEEE, 2008. http://hdl.handle.net/2237/12130.

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4

Lundberg, Daniel, Filip Wilson, Hjalmar Gunnarsson, Leo Sjörén, Robin Xu, and Erik Djurberg. "Long term aging and creep exposure for advanced heat resistant alloys : A phase analysis." Thesis, Uppsala universitet, Institutionen för materialvetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-446407.

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This project was ordered by Sandvik Materials Technology and was performed by a group of students at Uppsala university. The purpose of the project was to study precipitation behavior and structure stability in six advanced heat resistant alloys. Each sample were subjected to a creep rupture test in 600 or 700°C depending on the alloy type. Two parts of each alloy where examined; one part which had been affected by creep and another part which was unaffected by creep. A literature study was performed first to gain knowledge of the scientific theory utilized in this project, namely creep, precipitation hardening, and about the different materials which were analyzed. Preliminary results for the phase composition of the materials were obtained from a Thermo-Calc (TC) simulation. The SEM-images showed nothing noteworthy for any sample due to the roughness of the sample surfaces. The EDS-analysis showed chromium depletion in the centers of the aged samples of HT9 and Sanicro® 75X. Other minority phases such as Cr23C6 in Sanicro®70, P-phase and a titanium nitride phase in sanicro® 60X, VB in Esshete 1250 and Sigma-phase in 4C54 were identified using EDSmapping. It was found that when using XRD to analyze the phase compositions of small samples it is impractical to have the samples cast in bakelite beforehand. The XRD-results obtained in this project showed that more than 90% of the XRD diffractogram for every sample was graphite, which made the identification of minority phases impossible. The quality of the LOM-images varied greatly between samples, for 4C54 grain sizes were measured in all images, for Esshete 1250 grain sizes were measured for the crept sample, and for Sanicro® 60X measurements could only be taken from one image. Most of the sample preparation was insufficient to achieve the test results necessary for complete microstructural analysis and phase analysis of the samples. The mistakes in the practical steps of the project were noted and improvements for these mistakes are presented in the conclusion.
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5

Baxter, Christopher David Price. "An Experimental Study on the Aging of Sands." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/28450.

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There are numerous examples in the literature of time-dependent changes in the proper-ties of sands, or aging effects. Most of these aging effects are of increases in the cone penetration resistance. Time-dependent increases in penetration resistance have been measured in hydraulically placed fills and freshly densified deposits, with the largest in-creases following the use of ground modification techniques such as vibrocompaction, dynamic compaction, and blast densification. It is not known what causes these increases in penetration resistance to occur. The objective of this research was to gain an understanding of the possible mechanisms responsible for aging effects in sands. Current hypotheses to explain what causes aging effects in sands include increased interlocking of particles, internal stress arching, and precipitation of silica or carbonate minerals at the contacts between grains. To date, no unambiguous evidence has been presented to support these hypotheses. A laboratory testing program was developed to study the influence of different variables on the pres-ence and magnitude of aging effects. Three different sands were tested in rigid wall cells and buckets. Samples were aged under different effective stresses, densities, tempera-tures, and pore fluids. In every rigid wall cell, three independent measurements were made to monitor property changes during the aging process: small strain shear modulus using bender elements, electrical conductivity, and mini-cone penetration resistance. At the end of each test, detailed mineralogical tests were performed to assess changes in the chemistry of the samples and pore fluids. A total of 22 tests in rigid wall cells were per-formed with periods of aging ranging from 30 to 118 days. Mini-cone penetration resis-tances were measured in the buckets before and at various times during the aging process. Increases in the small strain shear modulus were measured with time. It was found that sand type and pore fluid composition greatly influenced the amount of increase in small strain shear modulus. Density was also found to influence the amount of increase in small strain shear modulus. Temperature was found to have little influence on the in-crease in small strain shear modulus with time. Changes in the chemistry of the samples were also measured with time. The dissolution and precipitation of minerals in solution was monitored with electrical conductivity measurements. In most of the tests, there was continual dissolution of minerals with time. Mineralogical studies and conductivity measurements indicated precipitation of carbonates and silica in two of the tests; however, scanning electron micrographs showed no visible evidence of precipitation. Despite the measured increases in small strain shear modulus and evidence of mineral precipitation, there were no increases in the mini-cone penetration resistance with time. This finding is significant and suggests that small-scale laboratory experiments do not capture the mechanism(s) that are responsible for time-dependent increases in penetration resistance in the field.
Ph. D.
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6

Harris, Nicholas Lionel. "Stress resistance and ageing in Saccharomyces cerevisiae." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400596.

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7

Macedo, Tânia Sofia Oliveira. "Improvement of the ageing resistance of 2YSZ ceramic." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/21896.

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Mestrado em Materiais e Dispositivos Biomédicos
Zirconia is a widely studied ceramic and it is applied in several areas such as engineering (solid oxide fuel cells, thermal barrier coatings) and biomedicine, in areas such as orthopedic and odontology. This material can be applied with the purpose to restore a body function that was compromised by a degenerative disease (orthopedic implants), in dental area and sensors due to its excellent mechanical properties, aesthetic characteristics and biocompatibility. However, this ceramic is sensitive to ageing and has a low hardness. To overcome these limitations, samples of Yttria Stabilized Zirconia doped with different oxides were developed and the goal was to improve the ageing resistance and mechanical properties of un-doped 2 mol% Yttria Stabilized Zirconia (2YSZ). A careful selection of the dopants and respective concentrations was performed. According to the literature, ceria (CeO2), silica (SiO2), alumina (Al2O3), lanthana (La2O3), ytterbia (Yb2O3) and manganese oxide (MnO2) improve the ageing resistance and/or the mechanical properties of Yttria Stabilized Zirconia (YSZ). In this study, thirteen different doped 2YSZ compositions were developed. For each selected dopant, three to four compositions were performed with different dopant concentrations. After a wet milling stage, the doped stabilized zirconia powders were obtained by spray-drying, from stabilized suspensions with a controlled nanometric particle size distribution. The obtained doped sprayed powders were characterized through several techniques, such as scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray fluorescence (XRF), density and specific surface area (SSA). Green bodies of all doped compositions were obtained by uniaxial pressing (70 MPa). High density ceramics (with relative density between 90% and approximately 99%) were achieved at low sintering temperatures (1350 °C and 1400 °C). The grain size of the sintered samples was measured by SEM images, and a dispersed microstructure with a nanometric grain size was observed for all 2YSZ doped samples. The crystallographic phases present in the doped samples were identified by XRD. In order to assess their thermal ageing resistance, the samples were subjected to a thermal treatment at low temperatures (200 °C) during a period of 36 hours. After this treatment, the fracture toughness of the aged samples was evaluated. From all the starting samples, those with better resistance to thermal ageing and fracture toughness were afterwards selected: samples of 2YSZ doped with CeO2 (0.50 wt%) and with SiO2 (0.25 wt%) and La2O3 (1.07 wt%). Cylindrical bodies of the selected doped 2YSZ compositions were obtained by two pressing stages - uniaxial and cold isostatic pressing - and sintered at 1350 ºC for 3 hours. The behaviour of the sintered samples was investigated in terms of hydrothermal ageing resistance, according to the specifications mentioned in ISO 13356:2008 (134 ± 2 ºC and 0.2 MPa), and mechanical properties: Vickers’ hardness along with fracture toughness and flexural strength. The amount of monoclinic zirconia, indicative of degradation, was determined by XRD after 5 hours of ageing test. Afterwards the mechanical behaviour (Vickers hardness, fracture toughness and flexural strength) of the aged samples was assessed. The results obtained in the present study demonstrate that adequate doped 2YSZ samples, with improved hydrothermal degradation resistance (9.87 % of monoclinic zirconia for SiO2 with La2O3 doped 2YSZ sample while un-doped 2YSZ presented a monoclinic phase higher than 15 %) can be obtained. The mechanical properties of the sample of 2YSZ doped with both oxides (SiO2 and La2O3), before and after the hydrothermal ageing, were practically maintained (1159 vs 1141 HV (hardness), 9.68 vs 9.15 MPa.m1/2 (fracture toughness) and 700 vs 698 MPa (flexural strength)). Nevertheless, a decrease of the mechanical properties was observed for both selected doped 2YSZ samples in relation to un-doped sample.
A zircónia é um cerâmico amplamente estudado e aplicado em diversas áreas da engenharia (células de combustível, revestimentos de barreiras térmicas) e biomedicina, em áreas como a ortopedia e a odontologia. Este material tem sido aplicado com o propósito de restaurar funções corporais que foram comprometidas por uma doença degenerativa (implantes ortopédicos), na área dentária e em sensores, devido às suas excelentes propriedades mecânicas, características estéticas e biocompatibilidade. Atualmente, existe a necessidade de desenvolver novos dispositivos com elevadas taxas de sucesso para as aplicações médicas mencionadas. O aumento da longevidade dos dispositivos protéticos para uma população jovem, mais ativa, com maior esperança de vida, requer o desenvolvimento de novos produtos, com desempenhos e designs fiáveis. O uso de Yttria Tetragonal Zirconia Polycrystal (Y-TZP) abriu possibilidades para desenvolver novos e promissores implantes, com novas e mais complexas geometrias, que não eram possíveis com outros cerâmicos, como por exemplo a alumina (mais frágil). Contudo, a zircónia cerâmica apresenta algumas limitações de trabalho: é sensível ao envelhecimento e apresenta baixa dureza. Devido a estas limitações, foram desenvolvidas várias amostras de zircónia estabilizada com 2 mol% de ítria (2YSZ), dopadas com diferentes óxidos, com o objetivo de avaliar e melhorar a resistência ao envelhecimento e propriedades mecânicas, quando comparadas com as amostras não dopadas. Para este efeito, foi realizada uma seleção criteriosa dos dopantes e respetivas concentrações. De acordo com a literatura, a céria (CeO2), sílica (SiO2), alumina (Al2O3), lantana (La2O3), íterbia (Yb2O3) e óxido de manganês (MnO2) melhoram a resistência ao envelhecimento e/ou as propriedades mecânicas da zircónia estabilizada com ítria (YSZ).Neste estudo, foram desenvolvidas treze diferentes composições dopadas, de zircónia estabilizada com 2 mol% de ítria (2YSZ). Por cada dopante selecionado foram preparadas três a quatro composições. Após uma etapa de moagem, os pós dopados de zircónia foram obtidos por atomização, a partir de suspensões estabilizadas, com uma distribuição de tamanho de partícula nanométrico controlado. Os pós atomizados foram caracterizados recorrendo a várias técnicas tais como microscopia eletrónica de varrimento (SEM), difração de raios-X (DRX), fluorescência de raios-X (FRX), densidade real, e área superficial específica (SSA). Os corpos em verde de todas as composições foram obtidos por prensagem uniaxial (70 MPa). Foram obtidos corpos cerâmicos com densidade elevada (com densidade relativa entre 90% e aproximadamente 99%) a uma temperatura de sinterização relativamente baixa (1350 ºC e 1400 ºC). O tamanho de grão das amostras sinterizadas foi medido através de imagens SEM, sendo verificado em todas as amostras de 2YSZ dopadas, uma microestrutura dispersa, com um tamanho de grão nanométrico. As fases cristalográficas presentes nas amostras dopadas foram identificadas por DRX. A fim de avaliar a resistência ao envelhecimento, as amostras sinterizadas foram submetidas a um tratamento térmico a baixas temperaturas (200 ºC) durante um período de 36 horas. Após este tratamento foi avaliada a tenacidade à fratura das amostras envelhecidas. Com base nestes resultados selecionaram-se as amostras que apresentavam melhor resistência ao envelhecimento térmico e tenacidade à fratura: 2YSZ dopada com CeO2 (0.50 wt%) e SiO2 (0.25 wt%) com La2O3 (1.07 wt%). Os pós das composições selecionadas foram sujeitos a prensagem uniaxial seguida de prensagem isostática a frio e sinterizadas a 1350 ºC durante 3 horas. Após sinterização, o comportamento destas amostras foi investigado em termos de resistência ao envelhecimento hidrotérmico e propriedades mecânicas: dureza de Vickers, tenacidade à fratura e resistência à flexão. Os testes de envelhecimento hidrotérmico foram realizados de acordo com as especificações mencionadas na norma ISO 13356:2008 (134 ± 2 ºC e 0.2 MPa). A percentagem de zircónia monoclínica, indicador de degradação, foi determinada por difração de raios-X após 5 horas de teste de envelhecimento hidrotérmico. Posteriormente, avaliou-se o comportamento mecânico (dureza de Vickers, a tenacidade à fratura e resistência à flexão) das amostras envelhecidas. O presente estudo demonstra que podem ser obtidas amostras cerâmicas de 2YSZ dopadas adequadas, com resistência à degradação hidrotérmico melhoradas (9.87 % de zircónia monoclínica para a amostra de 2YSZ dopada com SiO2 e La2O3, enquanto que a amostra de zircónia não dopada apresenta uma percentagem de fase monoclínica superior a 15 %). As propriedades mecânicas da amostra dopada com ambos os óxidos (SiO2 e La2O3), antes e após o envelhecimento hidrotérmico, foram praticamente mantidas (1159 vs 1141 HV (dureza), 9.68 vs 9.15 MPa.m1/2 (tenacidade à fratura) e 700 vs 698 MPa (resistência à flexão)). Porém, uma diminuição das propriedades mecânicas foi observada para ambas as amostras dopadas de 2YSZ selecionadas em relação à amostra de zircónia não dopada.
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8

Drake, Derek. "REST and the regulation of stress resistance, brain aging, and Alzheimer’s disease." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493396.

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Understanding how age-related stress in the brain is managed over a lifetime to maintain neuronal and cognitive function and prevent neurodegeneration will be critical for developing therapies to promote healthy aging. Here we show that repressor element 1-silencing transcription factor (REST) is induced in neurons of cognitively-intact aged individuals, but not those with Alzheimer’s disease (AD). REST protects against factors associated with AD, such as neuronal apoptosis and AD neuropathology, through direct binding and repression of pro-apoptotic genes and genes that contribute to AD neuropathology. REST nuclear levels in prefrontal cortex pyramidal neurons also correlate with increased AD age of onset and decreased AD neuropathology. REST protects against toxic insults associated with aging, such as oxidative stress. Moreover, REST regulates FOXO1, a fundamental regulator of the response to oxidative stress, to provide oxidative stress protection. REST and FOXO1 nuclear levels correlate in aging human cortical neurons. Furthermore, REST and FOXO1 expression are correlated with the expression of FOXO1-regulated genes that protect against oxidative stress in aged prefrontal cortex. REST also downregulates miR- 132 and miR-212, microRNAs that repress FOXO1 expression, and sensitize to oxidative stress. High levels of REST in the nucleus correlate with reduced longitudinal cognitive decline during aging. Moreover, REST nuclear levels account for a significant fraction of the variability of cognitive decline in the aging human population by a mixed model analysis. These results suggest that the neuroprotective function of REST is mediated, at least in part, through regulation of FOXO1 and miR-132/miR-212, and that REST is a critical determinant of stress resistance and cognitive preservation during aging.
Medical Sciences
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Platt, Thomas. "LEPTIN RESISTANCE INDUCED OBESITY AND DIABETES PROMOTE NEUROPATHOLOGICAL CHANGES IN THE AGING BRAIN." UKnowledge, 2014. http://uknowledge.uky.edu/biochem_etds/18.

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The aging brain is prone to the development of pathology and dementia. With a rapidly growing elderly population diagnoses of neurodegenerative diseases, such as Alzheimer’s disease (AD), frontotemporal dementia (FTD), and Parkinson’s disease are on the rise. Additionally, diabetes and obesity are linked to an increased risk of dementia. The convergence of this increasingly aged population with the obesity and diabetes epidemic give rise to new concerns regarding the future of prevention and treatment of neurodegenerative diseases. Our lab has previously shown that leptin, an adipokine involved in signaling satiety to the hypothalamus, can modulate the generation of the amyloid beta (Aβ) peptide (a toxic peptide associated with neurologic disease) and attenuate hyperphosphorylation of the tau protein (another peptide prone to forming large insoluble structures causing neurodegeneration). From these studies we have elucidated that leptin resistant mice (which develop severe obesity and type-2 diabetes mellitus) with knock-in mutations for the amyloid precursor protein (APP) and presenilin-1 (PS1) genes develop extensive vascular pathology and cognitive impairments. Interestingly, these mice do not display increased levels of amyloid deposition in the brain. Additionally, increased tau phosphorylation occurs in these mice with leptin resistance. As a follow up to this study db mice were transduced, via adeno-associated virus, with the tau P301L mutant to induce the development of tangle pathology. These mice displayed no cognitive deficits, yet they displayed increases in both tau phosphorylation and tangle count within the hippocampus. Collectively, these studies indicate leptin resistance, obesity, and type-2 diabetes mellitus promote the development of cerebrovascular and neurofibrillary tangle pathologies associated with neurodegeneration and dementia. These observations open many previously unexplored avenues for developing novel therapeutics to treat these devastating diseases.
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Li, Zhuo. "Modulation of IGFBP2 upon aging, obesity and insulin resistance in mice and humans." Thesis, Université Laval, 2011. http://www.theses.ulaval.ca/2011/28371/28371.pdf.

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Книги з теми "Aging resistant"

1

Stephens, Joseph R. Thermal aging effects in refractory metal alloys. [Cleveland, Ohio: National Aeronautics and Space Administration, Lewis Research Center, 1986.

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2

Nina, Anderson. Over 50 looking 30!: The secrets of staying young : the latest information on how to become wrinkle resistant and fight the signs of aging. East Canaan, Conn: Safe Goods, 1996.

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3

Dienstbier, Richard A. Building Resistance to Stress and Aging. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137454850.

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Malley, Gemma. The resistance. New York: Bloomsbury, 2008.

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5

M, Hashemian H., U.S. Nuclear Regulatory Commission. Office of Nuclear Regulatory Research. Division of Engineering., and Analysis and Measurement Services Corporation., eds. Aging of nuclear plant resistance temperature detectors. Washington, DC: Division of Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, 1990.

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6

The Resistance. New York: Bloomsbury U.S.A. Children's Books, 2008.

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7

Moss, Charles. Power of the five elements: The Chinese medicine path to healthy aging and stress resistance. Berkeley: North Atlantic Books, 2010.

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Moss, Charles. Power of the five elements: The Chinese medicine path to healthy aging and stress resistance. Berkeley: North Atlantic Books, 2010.

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9

Moss, Charles. Power of the five elements: The Chinese medicine path to healthy aging and stress resistance. Berkeley: North Atlantic Books, 2010.

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10

Minami, Kazutomo. Oiruhodo kekkan ga tsuyoku naru kenkōhō. Tōkyō: Achībumento Shuppan, 2016.

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Частини книг з теми "Aging resistant"

1

Barzilay, Joshua. "The Pre-Diabetic, Insulin-Resistant State." In The Epidemiology of Aging, 433–52. Dordrecht: Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5061-6_25.

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2

Bonomo, Robert A., and Louis B. Rice. "Multi-Drug Resistant Organisms in Long-Term Care Facilities." In Infectious Disease in the Aging, 257–75. Totowa, NJ: Humana Press, 2001. http://dx.doi.org/10.1007/978-1-59259-026-1_21.

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3

Donskoi, A. A., M. A. Shashkina, and G. E. Zaikov. "Climatic natural and artificial aging of materials." In Fire Resistant and Thermally Stable Materials Derived from Chlorinated Polyethylene, 170–75. London: CRC Press, 2023. http://dx.doi.org/10.1201/9780429070723-10.

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4

Koyama, Motomichi, Hiroshi Noguchi, and Kaneaki Tsuzaki. "Microstructural Crack Tip Plasticity Controlling Small Fatigue Crack Growth." In The Plaston Concept, 213–34. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7715-1_10.

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AbstractIn this chapter, we present a metallurgical–mechanical mechanism-based strategy for the design of fatigue-resistant metals. Specifically, we elucidate the importance of the metallurgical microstructure in a mechanical singular field (crack tip). The fatigue crack growth resistance is controlled through the crack tip “plasticity”, and the effect of the associated microstructure becomes significant when the crack is “small (or short)”. More importantly, the resistance to small crack growth determines a major portion of fatigue life and strength. Therefore, the microstructural crack tip plasticity is a key breakthrough to the development of fatigue-resistant metals. As successful examples of this concept, we introduce the effects of grain refinement, martensitic transformation, strain aging, dislocation planarity enhancement, and microstructure heterogeneity on small fatigue crack growths.
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Costa, Bruna, Joana Barros, and Fabíola Costa. "Antibiotic-Free Solutions for the Development of Biofilm Prevention Coatings." In Urinary Stents, 259–72. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04484-7_21.

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AbstractStents and urinary catheters are commonly used medical devices, whose need is forecasted to grow considering not only the world population increase but also its aging and sedentary lifestyle.Independently of the great development on biomaterials and device design, infection represents still a major cause of failure of these devices, with undeniable humane and economical costs. Different antibiotic-based solutions have appeared in the market to try to address the matter. However, there is growing evidence on the impact of antibiotic-resistant microorganisms on urinary tract medical-devices infections, and respective outcomes. A broad number of alternatives have been proposed, however, given the wide variability of results for different strategies, there remains a tremendous need to validate their clinical significance, particularly assuring patient safety. Additionally, most of these strategies might be advantageous while in combination with current therapies, so further studies are needed.
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Ehrenstein, Gottfried W., and Sonja Pongratz. "Principles of Aging." In Resistance and Stability of Polymers, 1–138. München: Carl Hanser Verlag GmbH & Co. KG, 2013. http://dx.doi.org/10.3139/9783446437098.001.

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Naiman, Tiffany. "Resisting the Politics of Aging." In Popular Music and the Politics of Hope, 267–82. New York : Routledge, 2019.: Routledge, 2019. http://dx.doi.org/10.4324/9781315165677-19.

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Yan, Wei, Wei Wang, Yiyin Shan, Ke Yang, and Wei Sha. "Thermal Ageing of Heat-Resistant Steels." In 9-12Cr Heat-Resistant Steels, 113–33. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14839-7_6.

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9

Ostry, M. E., D. D. Skilling, O. Y. Lee-Stadelmann, and W. P. Hackett. "Recovery of Somatic Variation in Resistance of Populus to Septoria Musiva." In Plant Aging, 113–16. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5760-5_13.

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Albright, Joseph F., and Julia W. Albright. "Aging and Altered Resistance to Infection." In Aging, Immunity, and Infection, 19–59. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1007/978-1-59259-402-3_2.

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Тези доповідей конференцій з теми "Aging resistant"

1

McCarthy, Roger L., and Stuart B. Brown. "Child Resistant Closure Performance Aging Study." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53370.

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Child poisoning has been dramatically reduced by the introduction of child resistant (CR) closures on some common home chemicals and pharmaceuticals. However, “child resistance” (often mischaracterized as “child proof”) is a mechanical design property that is neither well understood nor supported by a body of theory, nor that can be specified from engineering first principles. Instead, child resistance is an empirically developed and verified closure mechanical property derived from closure testing with child subjects, as specified by regulations under the Poison Prevention Packing Act (PPPA). The authors report their longitudinal study of a specific Type III CR closure over a period of decades made with materials from different suppliers over time and using different injection molding tools. The study examines if the property of “child resistance” persisted and if it correlated with the mechanical specifications of the closure actually measured and controlled in the closure manufacturing process. This data is combined with the authors’ mechanical measurements of closure performance. Child resistance, being a complex, empirically tested property, cannot be regularly tested in the normal manufacturing environment. Despite minor manufacturing process and specification changes, if the mechanical specifications are appropriate (e.g. not intended to produce changes in CR mechanical properties) and with adequate quality control, the property of child resistance persists.
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Ahmed, Sudan, Jeffrey C. Suhling, and Pradeep Lall. "The anand parameters of aging resistant doped solder alloys." In 2017 16th IEEE Intersociety Conference on Thermal and Thermomechanical Phenomena in Electronic Systems (ITherm). IEEE, 2017. http://dx.doi.org/10.1109/itherm.2017.7992647.

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3

Rahman, Md Tauhidur, Domenic Forte, Jim Fahrny, and Mohammad Tehranipoor. "ARO-PUF: An aging-resistant ring oscillator PUF design." In Design Automation and Test in Europe. New Jersey: IEEE Conference Publications, 2014. http://dx.doi.org/10.7873/date.2014.082.

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Rahman, Md Tauhidur, Domenic Forte, Jim Fahrny, and Mohammad Tehranipoor. "ARO-PUF: An aging-resistant ring oscillator PUF design." In Design Automation and Test in Europe. New Jersey: IEEE Conference Publications, 2014. http://dx.doi.org/10.7873/date2014.082.

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Yin, Fengshi, Zhen Xu, Bing Xue, Li Zhou, and Xuebo Jiang. "Precipitation of Nano-Sized Z-Phase in HR3C Austenitic Heat Resistant Steel." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-62075.

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Effect of heat treatment on the precipitation behavior of secondary phases in a HR3C austenitic heat resistant steel was investigated. The microstructure of the steel in solution-treated state consists of austenitic matrix and coarse Z-phase particles. After aging treatment at 650–950°C for 1h, M23C6-type carbide precipitates along random grain boundaries. Dense and homogeneous nanosized Z-phase precipitates within austenite grains are obtained by an aging treatment at a temperature between 800 and 900°C for 1h. The high density of dislocation walls produced during the water-cooling process after solution treatment facilitate the precipitation of the nanosized Z-phase. With increasing the aging temperature, the hardness initially drops, then increases and reaches a peak when the aging temperature is at 850°C due to the precipitation of the nanosized Z-phase.
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Han, Jun, Shaopeng Wu, Zhiyi Huang, Dehong Zhou, and Fujian Li. "Research on Low Temperature Rheological Behavior of Aging Resistant Bitumen and Mixture." In Second International Conference on Sustainable Construction Materials: Design, Performance, and Application. Reston, VA: American Society of Civil Engineers, 2012. http://dx.doi.org/10.1061/9780784412671.0029.

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7

Lakshminarayanan, V., S. Aziz, and J. M. Enoch. "Aging and the Hyperacuity Gap Function." In Noninvasive Assessment of the Visual System. Washington, D.C.: Optica Publishing Group, 1991. http://dx.doi.org/10.1364/navs.1991.md21.

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Hyperacuity is defined as the ability to perceive a difference in relative spatial localization of 2 or more visual stimuli to the order of 3 - 8 seconds of arc (Westheimer, 1979). The two dot vernier task is an example of a hyperacuity task. Hyperacuity stimuli are highly resistant to retinal image degradation and are, therefore, of clinical importance as a test of visual function in patients with partially opaque media or scattering bodies (see Enoch, et al., 1985 for a review). Hyperacuity techniques do not require a window through the anomalous media.
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Nakamura, Yusuke, Hiroshi Inano, Satoshi Hiroshima, Tatsuya Hirose, Masahiro Hamaguchi, and Hitoshi Okubo. "Partial Discharge Resistant Aging Mechanism of Nanocomposite Enamel Wires under Repetitive Surge Voltage Condition." In 2008 Annual Report Conference on Electrical Insulation and Dielectric Phenomena (CEIDP). IEEE, 2008. http://dx.doi.org/10.1109/ceidp.2008.4772764.

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MAKAREVIČIUS, Vidas, Arūnas BALTUŠNIKAS, Irena LUKOŠIŪTĖ, Rita KRIŪKIENĖ, and Albertas GRYBĖNAS. "EFFECT OF THERMAL AGING ON STRUCTURAL CHANGES IN P91 AND P5 HEAT RESISTANT STEELS." In METAL 2020. TANGER Ltd., 2020. http://dx.doi.org/10.37904/metal.2020.3521.

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Kim, Youngsam, and Soohyung Kim. "Design of aging-resistant Wi-Fi fingerprint-based localization system with continuous active learning." In 2018 20th International Conference on Advanced Communications Technology (ICACT). IEEE, 2018. http://dx.doi.org/10.23919/icact.2018.8323933.

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Звіти організацій з теми "Aging resistant"

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Hashemian, H., D. Beverly, D. Mitchell, and K. Petersen. Aging of nuclear plant resistance temperature detectors. Office of Scientific and Technical Information (OSTI), June 1990. http://dx.doi.org/10.2172/7072109.

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Bradford, Joe, Itzhak Shainberg, and Lloyd Norton. Effect of Soil Properties and Water Quality on Concentrated Flow Erosion (Rills, Ephermal Gullies and Pipes). United States Department of Agriculture, November 1996. http://dx.doi.org/10.32747/1996.7613040.bard.

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Concentrated flow erosion in rills, pipes, ephermal gullies, and gullies is a major contributor of downstream sedimentation. When rill or gullies form in a landscape, a 3- to 5-fold increase in soil loss commonly occurs. The balance between the erosive power of the flow and the erosion resistance of the bed material determines the rate of concentrated flow erosion. The resistance of the bed material to detachment depends primarily on the magnitude of the interparticle forces or cohesion holding the particles and aggregates together. The effect of soil properties on bed material resistance and concentrated flow erosion was evaluated both in the laboratory and field. Both rill erodibility and critical hydraulic shear were greater when measured in 9.0 m long rills under field conditions compared with laboratory mini-flumes. A greater hydraulic shear was required to initiate erosion in the field compared to the mini-flume because of the greater aggregate and clod size and stability. Once erosion was initiated, however, the rate of erosion as a function of hydraulic shear was greater under field conditions because of the greater potential for slaking upon wetting and the greater soil surface area exposed to hydraulic shear. Erosion tests under controlled laboratory conditions with the mini-flume allowed individual soil variables to be studied. Attempts to relate rill erosion to a group soil properties had limited success. When individual soil properties were isolated and studied separately or grouped separately, some trends were identified. For example, the effect of organic carbon on rill erodibility was high in kaolinitic soils, low in smectitic soils, and intermediate in the soils dominated by illite. Slow prewetting and aging increased the cohesion forces between soil particles and decreased rill erodibility. Quick prewetting increased aggregate slaking and increased erodibility. The magnitude of the effect of aging depended upon soil type. The effect of clay mineralogy was evaluated on sand/clay mixtures with montmorillonite (M), Illite (I), and kaolinite (K) clays. Montmorillonite/sand mixtures were much less erodible than either illite or kaolonite sand mixtures. Na-I and Na-K sand mixtures were more erodible than Ca-I and Ca-K due to increased strength from ionic bonding and suppression of repulsive charges by Ca. Na-M was less erodiblethan Ca-M due to increased surface resulting from the accessibility of internal surfaces due to Na saturation. Erodibility decreased when salt concentration was high enough to cause flocculation. This occurred between 0.001 mole L-1 and 0.01 mole L-1. Measuring rill erodibility in mini-flumes enables the measurement of cohesive forces between particles and enhances our ability to learn more about cohesive forces resisting soil detachment under concentrated water flow.
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Moghtadernejad, Sara, Ehsan Barjasteh, Ren Nagata, and Haia Malabeh. Enhancement of Asphalt Performance by Graphene-Based Bitumen Nanocomposites. Mineta Transportation Institute, June 2021. http://dx.doi.org/10.31979/mti.2021.1918.

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As the State of California continues to grow, demand for enhanced infrastructure such as roadways and highways escalates. In view of the current average highway lifespan of 15–20 years, the improvement of asphalt binders leads to material sustainability by decreasing required maintenance and increasing the lifespan of roadways. In the present investigation, enhancement of asphalt binder properties was achieved by different methods of mixing varying compositions of graphene nanoparticles with an SBS polymer and asphalt binder. Additionally, experimental evaluation and comparison of the rheological and mechanical properties of each specimen is presented. Graphene nanoparticles have attracted great curiosity in the field of highway materials due to their incredible rigidity, even in small quantities. Addition of as little as 1.0%nanoparticles in combination with polymers in an asphalt binder is expected to increase the rigidity of the material while also maintaining the beneficial polymer characteristics. Evaluation of the effect of the mixing design established that the methods for application of graphene to the polymer-modified asphalt binder are critical in the improvement of a roadway, resulting in resistance to premature aging and strain from constant road operation.
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