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Статті в журналах з теми "Age-related macular degeneration":
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SR, Bharathidevi. "Elevated Serum Hydrogen Sulfide in Age Related Macular Degeneration." Open Access Journal of Ophthalmology 8, no. 2 (July 5, 2023): 1–6. http://dx.doi.org/10.23880/oajo-16000281.
Introduction: Age related macular degeneration is one of the major causes of global blindness and vision impairment. The study was done to determine the levels of hydrogen sulfide (H2S) in AMD subjects in the study cohort. Methods: Twenty-six blood samples were collected, 12 control and 14 AMD subjects, the serum obtained from these samples were used for the measurement of H2S by Methylene blue (MB) assay and IL6 using ELISA. Results: We observed that both the levels of H2S and IL6 to be elevated in AMD subjects when compared to control and H2S and IL6 showed a positive correlation. Conclusion: We propose H2S to be a marker in both dry and wet AMD
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Bozkurt, M. K., B. T. Ozturk, H. Kerimoglu, I. Ersan, H. Arbag, and B. Bozkurt. "Association of age-related macular degeneration with age-related hearing loss." Journal of Laryngology & Otology 125, no. 3 (December 16, 2010): 231–35. http://dx.doi.org/10.1017/s0022215110002604.
AbstractObjective:To assess the association between age-related macular degeneration and age-related hearing loss in Turkish subjects aged 50 years or older.Study design and setting:Prospective, case–control study within a tertiary university hospital.Subjects and methods:Fifty subjects with age-related macular degeneration and 43 healthy subjects underwent ophthalmological and otolaryngological examination. Statistical analyses were conducted for the poorer eye and ear, comparing age-related hearing loss and pure tone average in the macular degeneration group versus controls.Results:Median pure tone average was significantly poorer in the macular degeneration group (35 dBHL) compared with controls (23 dBHL). In the macular degeneration group, hearing loss was significantly greater in dry type (43 dBHL) than wet type (32 dBHL) cases. There was a significant difference between the prevalence of varying degrees of hearing loss in the macular degeneration versus control groups, being respectively: mild, 50 and 35 per cent; moderate, 20 and 5 per cent; and severe, 6 and 0 per cent. There was a weak, but significant correlation between each patient's visual acuity and pure tone average results (rs = −0.37, p < 0.001).Conclusion:Age-related hearing loss is more common in patients with age-related macular degeneration. Such patients should be questioned regarding hearing difficulty, and referred to an otolaryngologist if appropriate.
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Thomas, Catherine J., Rukhsana G. Mirza, and Manjot K. Gill. "Age-Related Macular Degeneration." Medical Clinics of North America 105, no. 3 (May 2021): 473–91. http://dx.doi.org/10.1016/j.mcna.2021.01.003.
Starr, Christopher E., David R. Guyer, and Lawrence A. Yannuzzi. "Age-related macular degeneration." Postgraduate Medicine 103, no. 5 (May 1998): 153–64. http://dx.doi.org/10.3810/pgm.1998.05.480.
C, Christoph Richter, and Hamdy Shaban H. "Age-Related Macular Degeneration." Journal of Medical Sciences 2, no. 1 (February 10, 2009): 18–24. http://dx.doi.org/10.2174/1996327000902010018.
Apte, Rajendra S. "Age-Related Macular Degeneration." New England Journal of Medicine 385, no. 6 (August 5, 2021): 539–47. http://dx.doi.org/10.1056/nejmcp2102061.
Дисертації з теми "Age-related macular degeneration":
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Gu, Jiayin. "Biomarkers for Age-Related Macular Degeneration." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1225388164.
Renganathan, Kutralanathan. "Oxidative stress and age related macular degeneration." online version, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1193002743.
Age-related macular degeneration (AMD) affects 12.7 million people in Europe and North America (Klein et al., 1995 Klein et al. 1999). As a combination of decreasing birth rate and increasing longevity alter the demographic of the population, the impact of this disease can only increase. This places an immense burden, not only on the individuals afflicted by the condition, but on the financial resources of society as a whole. Unfortunately, treatment for AMD is still very restricted, and even our understanding of the pathogenesis of the disease is far from complete One concern in tackling the growing problem of AMD is that methods used in the assessment of the condition are limited, usually based on fundus appearance and visual acuity. The aim of this study was to develop a battery of electrophysiological tests which would be sensitive to the most subtle changes in retinal function in AMD. Such tests may aid diagnosis, provide a more sensitive measure of disease progression, and allow an early identification of phenotypic subtypes. Protocols were included for the recording of the focal rod ERG, the focal cone ERG, the S-cone ERG and the dynamic focal cone ERG, along with psychophysical tests of colour vision and dark adaptation. These tests were then applied to 31 subjects with ARM (12 with bilateral ARM, 11 with unilateral wet AMD and 8 with unilateral dry AMD), and 28 controls. In the analysis of ERG amplitudes a ratio of focal to full-field amplitude was introduced as a novel means of reducing intersubject variability in response. This was found to increase the accuracy of all tests in distinguishing between subject groups. The greatest separation between ARM and control groups was provided by the dynamic tests of visual function i.e. rod-cone break time of the dark adaptation function, and time constant of recovery of the dynamic focal cone ERG. The time to rod-cone break also showed potential in identifying subjects at increased risk of exudative retinal changes. Subjects were assigned to groups in this study on the basis of fundus appearance. However, individuals within each subject group showed a range of retinal function which belied the homogeneity of retinal signs. This raises the question of whether 'form' or 'function' should form the basis of classification and assessment of individuals with ARM and AMD.
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Evans, Jennifer Rosemary. "Age-related macular degeneration in the UK." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2003. http://researchonline.lshtm.ac.uk/682315/.
The aim of this thesis was to investigate the prevalence and impact of age-related macular degeneration (AMD) causing visual impairment in people aged 75 years and above in the UK. A secondary objective was to investigate a small number of potential risk factors for AMD. This was an add-on study to the MRC Trial of the Assessment and Management of Older People in the Community. The prevalence of AMD causing visual impairment was estimated at 3.7% (95% confidence interval 3.2% to 4.2%) in people aged 75 years and above. This prevalence increased sharply with age. There was a higher risk of AMD causing visual impairment in women. There were estimated to be approximately 192,000 people aged 75 years and above in the UK living in the community with visual impairment due to AMD (95% confidence interval 144,000 to 239,000) of whom 60,000 are aged 90 years or above. The prevalence of AMD causing visual impairment did not vary by socio-economic group or region. After controlling for appropriate confounding factors, compared to people not visually impaired, people visually impaired due to AMD were more likely to have functional difficulties, report poor health and be depressed. They were more likely to be in the worst quintile for the home management and mobility dimensions of the Sickness Impact Profile (SIP). After controlling for appropriate confounding factors including binocular acuity score, compared to people visually impaired due to other causes, people visually impaired due to AMD were more likely to have functional difficulties and report poor health and less likely to be in the worst quintile for SIP body care and movement dimension or die. There was an association between smoking status and risk of being visually impaired due to AMD. This effect was particularly strong in people aged 75-79 years of age. In these people there was a dose-response relationship between pack years of smoking and risk of AMD causing visual impairment. There were no statistically significant associations between alcohol consumption, cardiovascular disease and reproductive factors (in women) and AMD causing visual impairment.
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Goverdhan, Srinivas. "Immunogenetic pathways in age related macular degeneration." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/66006/.
Renganathan, Kutralanathan. "Oxidative Damage and Age Related Macular Degeneration." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1193002743.
Wang, Yang. "Gene Discovery for Age-related Macular Degeneration." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1228364622.
NI, JIAQIAN. "Plasma Biomarkers for Age-Related Macular Degeneration." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1236700270.
Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in older Americans. There has been a long standing interest in the role of diet in the development of AMD. As early as the first National Health and Nutrition Examination Survey in the 1970s, higher intakes of fruits and vegetables were inversely correlated with the prevalence of AMD. Carotenoids and omega3 fatty acids are the most studied dietary factors due to strong biological plausibility. However, evidence from epidemiologic studies and clinical trials on the relations has been inconsistent.
Chapter I prospectively examined the intakes of lutein/zeaxanthin and other common carotenoids in relation to the risk of AMD over more than two decades of follow-up among two large US cohorts, the Nurses’ Health Study and Health Professionals Follow-Up Study. We assessed nutrient intakes by repeated food frequency questionnaires. We also computed bioavailable plasma carotenoid scores directly from food intake using validated regression models. Cox proportional hazards models were used to compute the associations. Higher intakes of bioavailable carotenoids (except lycopene) were inversely associated with advanced AMD but not intermediate AMD. Analyses based on bioavailable intakes resulted in stronger associations than conventional nutrient intakes.
Chapter II prospectively evaluated the marine long-chain omega3 fatty acids. We found that long-chain omega3 fatty acids were inversely associated with visually significant intermediate AMD. There was no association with advanced AMD; however, the totality of current evidence for advanced AMD is also discordant.
Chapter III further investigated the plant-derived omega3 fatty acids, α-linolenic acid (ALA). We found that higher intake of ALA was associated with intermediate AMD before 2002 but not after. This coincides with the same time period when trans ALA was found in our participants’ blood and in mayonnaise, a primary food source of ALA. Whether trans ALA mediates this positive association warrants further studies.
Although randomized trials are usually believed as the “gold standard”, dietary factors are hard to be adequately studied by randomized trials due to the complexities of diet and disease relations. Thus, findings in this thesis from large long-term prospective cohort studies provide the next best form of evidence.
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Wang, Yang. "Gene discovery of age-related macular degeneration." Cleveland, Ohio : Case Western Reserve University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1228364622.
Holz, Frank G., Daniel Pauleikhoff, Richard F. Spaide, and Alan C. Bird, eds. Age-related Macular Degeneration. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-22107-1.
Wykoff, Charles, Mariam Hussain, T. Ashwini Kini, and Bayan Al Othman. Age-Related Macular Degeneration. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-36973-6.
Alberti, Winfried E., Gisbert Richard, and Robert H. Sagerman, eds. Age-Related Macular Degeneration. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56439-0.
Holz, Frank G., Daniel Pauleikhoff, Richard F. Spaide, and Alan C. Bird. Age-related macular degeneration. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-05199-3.
Institute, National Eye, ed. Age-related macular degeneration. Bethesda, Md: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Eye Institute, 1985.
Частини книг з теми "Age-related macular degeneration":
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Penfold, Philip L., James Wong, Diana van Driel, Jan M. Provis, and Michele C. Madigan. "Immunology and Age-Related Macular Degeneration." In Macular Degeneration, 25–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-26977-0_2.
Theisler, Charles. "Macular Degeneration/ Age Related Macular Degeneration (AMD)." In Adjuvant Medical Care, 208–10. New York: CRC Press, 2022. http://dx.doi.org/10.1201/b22898-213.
Rabina, Gilad, and Anat Loewenstein. "Age-Related Macular Degeneration." In Encyclopedia of Ophthalmology, 1–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-35951-4_984-1.
Khandhadia, Sam, Jocelyn Cherry, and Andrew John Lotery. "Age-Related Macular Degeneration." In Advances in Experimental Medicine and Biology, 15–36. New York, NY: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-0653-2_2.
Yoshimura, Nagahisa, and Masanori Hangai. "Age-related macular degeneration." In OCT Atlas, 149–228. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-38625-1_6.
Rabina, Gilad, and Anat Loewenstein. "Age-Related Macular Degeneration." In Encyclopedia of Ophthalmology, 50–56. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_984.
Hellman, Justin, and Glenn Yiu. "Age-Related Macular Degeneration." In Current Practices in Ophthalmology, 35–70. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8545-1_2.
Тези доповідей конференцій з теми "Age-related macular degeneration":
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Sunness, Janet S., and Robert W. Massof. "The Focal EOG in Age-Related Macular Degeneration." In Noninvasive Assessment of Visual Function. Washington, D.C.: Optica Publishing Group, 1985. http://dx.doi.org/10.1364/navf.1985.tub1.
Studies of electrooculogram testing of patients with age-related drusen and macular degeneration (aka senile macular degeneration, or SMD) have shown differing results. Of the two largest studies, one1 showed most patients with severe SMD to have low Arden ratios and most patients with drusen to have normal Arden ratios, and the other2 showed one-third of patients with drusen and SMD to have abnormal EOGs, with no correlation to severity of the clinical picture. These studies were performed using a non-ganzfeld type of stimulation. A recent study by us3 of twenty-one patients with drusen and SMD, using ganzfeld EOG testing, found that all patients had normal Arden ratios.
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van Grinsven, Mark J. J. P., Yara T. E. Lechanteur, Johannes P. H. van de Ven, Bram van Ginneken, Thomas Theelen, and Clara I. Sánchez. "Automatic age-related macular degeneration detection and staging." In SPIE Medical Imaging, edited by Carol L. Novak and Stephen Aylward. SPIE, 2013. http://dx.doi.org/10.1117/12.2007563.
Chou, Jim-Son, and Albert C. Ting. "AMO® TeledioptricTMSystem for age-related macular degeneration." In OE/LASE '94, edited by Donn M. Silberman. SPIE, 1994. http://dx.doi.org/10.1117/12.176834.
Mohaghegh, N., E. Ghafar Zadeh, and S. Magierowski. "Wearable diagnostic system for age-related macular degeneration." In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2016. http://dx.doi.org/10.1109/embc.2016.7592097.
Miura, Masahiro, and Ann E. Eisner. "Three Dimensional Imaging in Age-Related Macular Degeneration." In Vision Science and its Applications. Washington, D.C.: OSA, 2001. http://dx.doi.org/10.1364/vsia.2001.fb3.
Hijazi, Mohd Hanafi Ahmad, Frans Coenen, and Yalin Zheng. "Age-Related Macular Degeneration Screening Using Data Mining Approaches." In 2013 1st International Conference on Artificial Intelligence, Modelling & Simulation (AIMS). IEEE, 2013. http://dx.doi.org/10.1109/aims.2013.55.
Elsner, Ann E., Mariane B. M. Kairala, Michael C. Cheney, Stephen A. Burns, and Masahiro Miura. "Imaging with polarization analysis in age-related macular degeneration." In Frontiers in Optics. Washington, D.C.: OSA, 2003. http://dx.doi.org/10.1364/fio.2003.mc4.
Lipshitz, Isaac. "Intraocular Implanted Mirror Telescope For Age- Related Macular Degeneration." In Bio-Optics: Design and Application. Washington, D.C.: OSA, 2011. http://dx.doi.org/10.1364/boda.2011.btud1.
Ting, Albert C., Donald G. Koch, and Jim-Son Chou. "Diffractive-refractive lens system for age-related macular degeneration." In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, edited by Jean-Marie A. Parel and Qiushi Ren. SPIE, 1993. http://dx.doi.org/10.1117/12.147526.
Burlina, P., D. E. Freund, N. Joshi, Y. Wolfson, and N. M. Bressler. "Detection of age-related macular degeneration via deep learning." In 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016). IEEE, 2016. http://dx.doi.org/10.1109/isbi.2016.7493240.
Liu, Yunjie, Mengmei Ni, Rui Wu, Zhirui Yang, Xuejiao Zhu, and Jinyao Chen. Lutein and age-related macular degeneration: a comprehensive systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0091.
Wang, Xiaoqin, Liuzhi Zeng, Ming Chen, and LongQian Liu. Choroidal vascular changes in age-related macular degeneration: a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2020. http://dx.doi.org/10.37766/inplasy2020.10.0041.
Kyosseva, Svetlana V., Sudipta Seal, and James F. McGinnis. Cerium Oxide Nanoparticles Inhibit Map Kinases Activation in the Retina of VLDLR Mouse Model of Age-related Macular Degeneration. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, November 2018. http://dx.doi.org/10.7546/crabs.2018.11.07.
SHI, Suisui, Lei YANG, Guohui Yang, Baoyu QI, and Guojun CHAO. Efficacy of traditional Chinese medicine combined with ranibizumab in patients with neovascular age-related macular degeneration: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2022. http://dx.doi.org/10.37766/inplasy2022.10.0077.
Zhang, Yun, Zhaolun Cai, Xueting Liu, Tiancong Chang, Xun Li, You Tang, Bo Zhang, and Meixia Zhang. Comparative efficacy and safety of anti-vascular endothelial growth factor monotherapies for neovascular age-related macular degeneration: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0007.
Regular monthly and “as needed” injections for wet age-related macular degeneration are similar in effect. National Institute for Health Research, January 2016. http://dx.doi.org/10.3310/signal-000185.
