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Добірка наукової літератури з теми "616.07/54/0151"

Автор: Grafiati
Опубліковано: 27 липня 2024
Оновлено: 28 липня 2024

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Статті в журналах з теми "616.07/54/0151"

1

SANTOS, Bárbara Loiola, Arthur Maynart Pereira OLIVEIRA, Hélio Araújo OLIVEIRA, and Robson Luis Oliveira de AMORIM. "Primary central nervous system tumors in Sergipe, Brazil: descriptive epidemiology between 2010 and 2018." Arquivos de Neuro-Psiquiatria 79, no. 6 (June 2021): 504–10. http://dx.doi.org/10.1590/0004-282x-anp-2020-0151.

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ABSTRACT Background: Central nervous system (CNS) tumors are a heterogeneous group with high morbidity and mortality. Objectives: To describe the epidemiology of primary CNS tumors diagnosed in the state of Sergipe from 2010 to 2018. Methods: We evaluated histopathological and immunohistochemical reports on primary CNS tumors diagnosed in Sergipe, Brazil, between 2010 and 2018 and collected data regarding age, sex, location, World Health Organization (WHO) classification and histology. Results: Altogether, 861 primary CNS tumors were found. Tumors in brain locations occurred most frequently (50.8%; n=437). The neoplasms observed were most prevalent in the age range 45‒54 years (20.4%; n=176). Grade I tumors occurred most frequently, corresponding to 38.8% of the cases (n=38) in the age group of 0‒14 years, and 44.6% (n=340) in the population ≥15 years old. Between 0 and 14 years of age, other astrocytic tumors were the most prevalent (29.6%; n=29). In the age group between 15 and 34, gliomas were the most frequent (32.7%; n=54). Meningiomas predominated in the age group of 35 years and above, comprising 47.5% of cases (n=206) in the 35‒74 age group; and 61.2% (n=30) among patients over 75 years old. Conclusion: The epidemiology of primary CNS tumors in Sergipe between 2010 and 2018 is consistent with data in other current studies on the subject. Studies on the epidemiological evolution of these entities in Sergipe are needed.
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2

Miraglia, Erica, Federico De Angelis, Elena Gazzano, Hossain Hassanpour, Angela Bertagna, Elisabetta Aldieri, Alberto Revelli, and Dario Ghigo. "Nitric oxide stimulates human sperm motility via activation of the cyclic GMP/protein kinase G signaling pathway." REPRODUCTION 141, no. 1 (January 2011): 47–54. http://dx.doi.org/10.1530/rep-10-0151.

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Nitric oxide (NO), a modulator of several physiological processes, is involved in different human sperm functions. We have investigated whether NO may stimulate the motility of human spermatozoa via activation of the soluble guanylate cyclase (sGC)/cGMP pathway. Sperm samples obtained by masturbation from 70 normozoospermic patients were processed by the swim-up technique. The kinetic parameters of the motile sperm-rich fractions were assessed by computer-assisted sperm analysis. After a 30–90 min incubation, the NO donor S-nitrosoglutathione (GSNO) exerted a significant enhancing effect on progressive motility (77, 78, and 78% vs 66, 65, and 62% of the control at the corresponding time), straight linear velocity (44, 49, and 48 μm/s vs 34, 35, and 35.5 μm/s), curvilinear velocity (81, 83, and 84 μm/s vs 68 μm/s), and average path velocity (52, 57, and 54 μm/s vs 40, 42, and 42 μm/s) at 5 μM but not at lower concentrations, and in parallel increased the synthesis of cGMP. A similar effect was obtained with the NO donor spermine NONOate after 30 and 60 min. The GSNO-induced effects on sperm motility were abolished by 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one (a specific sGC inhibitor) and mimicked by 8-bromo-cGMP (8-Br-cGMP; a cell-permeating cGMP analog); the treatment with Rp-8-Br-cGMPS (an inhibitor of cGMP-dependent protein kinases) prevented both the GSNO- and the 8-Br-cGMP-induced responses. On the contrary, we did not observe any effect of the cGMP/PRKG1 (PKG) pathway modulators on the onset of hyperactivated sperm motility. Our results suggest that NO stimulates human sperm motility via the activation of sGC, the subsequent synthesis of cGMP, and the activation of cGMP-dependent protein kinases.
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3

Bertolaccini, Maria, Giovanni Sanna, Shvaita Ralhan, Laura Gennari, Joan Merrill, Graham Hughes, and Munther Khamashta. "Antibodies directed to protein S in patients with systemic lupus erythematosus: prevalence and clinical significance." Thrombosis and Haemostasis 90, no. 10 (2003): 636–41. http://dx.doi.org/10.1160/th03-03-0151.

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SummaryAntibodies directed against protein S (anti-ProtS) may be involved in the development of thrombosis in patients with the antiphospholipid syndrome. We assessed the prevalence and clinical significance of anti-ProtS and evaluated their immunological characteristics in 184 patients with SLE and 99 healthy donors. All patients were tested for IgG anti-ProtS by an in-house ELISA. Plasma levels and functional activity of protein S were also tested.Anti-ProtS were found in 57 patients (31%) and 4 healthy controls (4%). Patients with thrombosis had anti-ProtS more frequently than controls (29% vs 4%, OR 9.5 [95% CI 3.07-29.3], p<0.0001). Anti-ProtS were more frequent in patients with venous thrombosis and in those with arterial thrombosis, than in controls (41% vs. 4%, OR 16.5 [95% CI 5-54], p< 0.0001 and 23% vs. 4%, OR 7 [95%CI 2.1-23.5], p=0.0008, respective-ly). Patients with prematurity, preeclampsia and intra-uterine growth restriction had anti-ProtS more frequently than the control group (36%, 47% and 44% vs. 4%; OR 13.6 [95% CI 2.8-66], p=0.003, OR 21 [95% CI 5-86], p<0.0001 and OR 19 [95% CI 4-99], p=0.0014, respectively). Plasma levels of free protein S were not statistically different between patients with and without anti-ProtS and controls (77.9% [20.7-100] vs. 83.7% [52.7-100] vs. 89% [62-101], respectively). Free protein S functional activity was no different between subgroups (105% [48-230] in anti-ProtS positive vs. 123% [95-283] in anti-ProtS negative vs. 136% [60-174] in controls).Anti-ProtS are frequent in SLE patients with thrombosis and pregnancy morbidity. These antibodies do not interfere with free protein S in plasma since its level and/or functional activity are not impaired.
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4

Peña, Elizabeth D., Ronald B. Gillam, and Lisa M. Bedore. "Dynamic Assessment of Narrative Ability in English Accurately Identifies Language Impairment in English Language Learners." Journal of Speech, Language, and Hearing Research 57, no. 6 (December 2014): 2208–20. http://dx.doi.org/10.1044/2014_jslhr-l-13-0151.

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Purpose To assess the identification accuracy of dynamic assessment (DA) of narrative ability in English for children learning English as a 2nd language. Method A DA task was administered to 54 children: 18 Spanish–English-speaking children with language impairment (LI); 18 age-, sex-, IQ- and language experience-matched typical control children; and an additional 18 age- and language experience-matched comparison children. A variety of quantitative and qualitative measures were collected in the pretest phase, the mediation phase, and the posttest phase of the study. Exploratory discriminant analysis was used to determine the set of measures that best differentiated among this group of children with and without LI. Results A combination of examiner ratings of modifiability (compliance, metacognition, and task orientation), DA story scores (setting, dialogue, and complexity of vocabulary), and ungrammaticality (derived from the posttest narrative sample) classified children with 80.6% to 97.2% accuracy. Conclusion DA conducted in English provides a systematic means for measuring learning processes and learning outcomes, resulting in a clinically useful procedure for identifying LIs in bilingual children who are in the process of learning English as a second language.
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5

Mor, Rahul S., Arvind Bhardwaj, Sarbjit Singh, and Anish Sachdeva. "Productivity gains through standardization-of-work in a manufacturing company." Journal of Manufacturing Technology Management 30, no. 6 (October 21, 2019): 899–919. http://dx.doi.org/10.1108/jmtm-07-2017-0151.

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Purpose The purpose of this paper is to identify the non-value-adding activities (NVAs) of core making process and to eliminate them through the standardization-of-work (SW) procedures in a manufacturing company. Design/methodology/approach The action-research methodology was adopted for the current study. First, various lean tools were identified through literature review, and the bottleneck area was identified in discussion with the shop-floor executives. NVAs were recorded after a continuous process study including method study and motion analysis followed by the standard operating procedure. Second, the standardized work combination tables were prepared and NVAs were eliminated using the SW procedures. SW has been opted because it is a set of actions which helps in analyzing, improving and controlling the process and it leads to continual improvement. Findings The production logbook revealed that the capacity in this particular workstation was 54 pieces per 7 h work shift against the current production of approx. 45–50 pieces (past data). SW saved 31.6 s per cycle which boosted the production up to 58 pieces per 7 h work shift. Finally, the authors came to know that the productivity of this particular process increased up to 6.5 percent which may upsurge if this action is executed continually with the support from shop-floor executives and management. These results were also compared with previous research works in this area and found significant relevance, and hence, the results appear to be reliable. Research limitations/implications This is a unique study in itself which explores the lean model by assessing NVAs of core making process. The proposed approach needs to be tested across different other core making processes of the case company so as to generalize the effectiveness of SW as well as the results obtained in the current study. Practical implications The current study illustrates an important step to give more visibility to the lean concept by addressing the problem of lack of standard procedures. This study will help the shop-floor executives and managers to focus their efforts in achieving high performance through effective implementation of SW. The study should be of the interest of researchers in the area of lean manufacturing, operations management, productivity analysis, etc. Originality/value The findings of this study are based on the problem formulation for productivity gains using SW procedures in the case company. The study introduces a new perspective for the execution of SW for core making processes. SW created transparency in workflow, enhanced the safety and eliminated the 3Ms. The outcome of the current study was discussed with the production team and management of the company to validate the productivity gains and received an optimistic response. Most importantly, these improvements were achieved with no investment in machinery or tooling.
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6

Camire. "Moving Forward." Cereal Foods World, 2009. http://dx.doi.org/10.1094/cfw-54-4-0151.

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7

Özkılıç, Anıl Çağla, Ahmet Çetin, Burcu Bayoğlu, Huriye Balcı, and Müjgan Cengiz. "Association between MTHFR C677T polymorphism and folate, vitamin B12, homocysteine, and DNA fragmentation in patients with ovarian cancer." Turkish Journal of Biochemistry 41, no. 6 (January 1, 2016). http://dx.doi.org/10.1515/tjb-2016-0151.

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AbstractObjective:Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme that regulates the metabolism of methionine and folate.Materials and methods:This case-control study was conducted in Istanbul University Cerrahpasa Medical Faculty. We studied 50 ovarian cancer patients and 54 healthy controls. TheResults:We found no correlation between theConclusion:Our findings suggest that
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8

Ortega Vega, Marta, Chris Attoe, Hannah Iannelli, Aleks Saunders, and Sean Cross. "Current perspectives on public mental health training provision: a scoping review." Journal of Public Mental Health ahead-of-print, ahead-of-print (July 31, 2021). http://dx.doi.org/10.1108/jpmh-11-2020-0151.

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Purpose Public mental health training can effectively support well-being at a population level. The application of this type of training is increasingly prevalent, however, training evaluation is currently limited and inconsistent. This paper aims to summarise the characteristics of public mental health training available in England, presents key quality criteria for this training and identifies gaps in training provision. Design/methodology/approach This paper uses a pragmatic mixed-methods approach including database and Google Searches, focus groups and survey methods. The data analysis included a structured data extraction template for the training availability scoping and thematic analysis of the survey and focus groups. Findings This paper identifies a total of 74 training courses targeting workplace employees, young people and the general population. Most courses were delivered face-to-face (54), followed by e-learning (16) and blended modalities (4). This paper derives four core quality principles, focussing on the training approach, key features of training, trainer attributes and evaluation. There were no significant gaps in training provision, although areas for future development included consistency in public mental health terminology, systems and populations requiring additional training and the logistics of training delivery, etc. Originality/value The results contribute to the evidence base of interventions that are currently available, supporting the efforts to evaluate the impact of training provision in this area. This paper provides a novel approach to assessing training quality and discuss areas for development and innovation in this field.
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9

Nath, Ratnadeep, and Krishnan Murugesan. "Numerical investigation of double-diffusive mixed convection of Fe3O4/Cu/Al2O3-water nanofluid flow through a backward-facing-step channel subjected to magnetic field." International Journal of Numerical Methods for Heat & Fluid Flow ahead-of-print, ahead-of-print (June 8, 2021). http://dx.doi.org/10.1108/hff-02-2021-0151.

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Purpose This study aims to investigate the buoyancy-induced heat and mass transfer phenomena in a backward-facing-step (BFS) channel subjected to applied magnetic field using different types of nanofluid. Design/methodology/approach Conservation equations of mass, momentum, energy and concentration are used through velocity-vorticity form of Navier–Stokes equations and solved using Galerkin’s weighted residual finite element method. The density variation is handled by Boussinesq approximation caused by thermo-solutal buoyancy forces evolved at the channel bottom wall having high heat and concentration. Simulations were carried out for the variation of Hartmann number (0 to 100), buoyancy ratio (−10 to +10), three types of water-based nanofluid i.e. Fe3O4, Cu, Al2O3 at χ = 6%, Re = 200 and Ri = 0.1. Findings The mutual interaction of magnetic force, inertial force and nature of thermal-solutal buoyancy forces play a significant role in the heat and mass transport phenomena. Results show that the size of the recirculation zone increases at N = 1 for aiding thermo-solutal buoyancy force, whereas the applied magnetic field dampened the fluid-convection process. With an increase in buoyancy ratio, Al2O3 nanoparticle shows a maximum 54% and 67% increase in convective heat and mass transfer, respectively at Ha = 20 followed by Fe3O4 and Cu. However, with increase in Ha the Nuavg and Shavg diminish by maximum 62.33% and 74.56%, respectively, for Fe3O4 nanoparticles at N = 5 followed by Al2O3 and Cu. Originality/value This research study numerically examines the sensitivity of Fe3O4, Cu and Al2O3 nanoparticles in a magnetic field for buoyancy-induced mixed convective heat and mass transfer phenomena in a BFS channel, which was not analyzed earlier.
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Книги з теми "616.07/54/0151"

1

F, Watkinson A., and Adam Andy, eds. Interventional radiology: A practical guide. Oxford: Radcliffe Medical Press, 1996.

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2

S, Bickley Lynn, and Hoekelman Robert A, eds. Bates' guide to physical examination and history taking / Lynn S. Bickley, Robert A. Hoekelman. 7th ed. Philadelphia: Lippincott, 1999.

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3

M, Links Jonathan, ed. Medical imaging signals and systems. Upper Saddle River, NJ: Pearson Prentice Hall, 2006.

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4

Introduction to the mathematics of medical imaging. 2nd ed. Philadelphia, PA: Society for Industrial and Applied Mathematics, 2008.

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5

Introduction to the Mathematics of Medical Imaging. 2008.

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6

Introduction to the Mathematics of Medical Imaging. Prentice Hall, 2003.

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7

Webb's physics of medical imaging. 2nd ed. Boca Raton: Taylor & Francis, 2012.

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8

The Essential Physics of Medical Imaging (2nd Edition). 2nd ed. Lippincott Williams & Wilkins, 2001.

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9

DeGowins Diagnostic Examination (Degowin's Diagnostic Examination). 9th ed. McGraw-Hill Medical Publishing, 2008.

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10

Applied Medical Image Processing: A Basic Course. Taylor & Francis Group, 2014.

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