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Автор: Grafiati
Опубліковано: 7 липня 2024

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Статті в журналах з теми "46L87":

1

Meng, Chaoqun, Guangxin Chen, Yue Liu, Da Wen, Jia Cui, Li Dong, Zhiqiang Yang, et al. "miR-4687-5p Affects Intracellular Survival of Mycobacterium tuberculosis through Its Regulation of NRAMP1 Expression in A549 Cells." Microorganisms 12, no. 1 (January 22, 2024): 227. http://dx.doi.org/10.3390/microorganisms12010227.

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Tuberculosis (TB), as one of the leading causes of death, poses a serious predicament to the world. MicroRNAs (miRNAs) play a role in the post-transcriptional regulation of gene expression. It has been reported that the expression of miRNAs changes upon mycobacterial infection; the screening and identification of miRNAs regulating the expression of genes could benefit our understanding of TB pathogenesis and generate effective strategies for its control and prevention. In this study, luciferase assays showed that miR-4687-5p is bound to the 3′-untranslated region of natural resistance-associated macrophage protein 1 (NRAMP1). Additionally, we found a significant increase in miR-4687-5p expression in Mycobacterium tuberculosis (Mtb)-infected A549 cells. Concomitantly, we detected a reduced level of NRAMP1 expression, suggesting that NRAMP1 is one of the targets of miR-4687-5p. Infection experiments evidenced that the transfection of miR-4687-5p induced a decrease in NRAMP1 expression and increased intracellular Mtb loads post-infection, indicating that miR-4687-5p promotes the intracellular survival of Mtb through its downregulation of the NRAMP1 protein level. We also found that the transfection of miR-4687-5p induced increased apoptosis and decreased cell proliferation post-infection with Mtb. The results presented in our study suggest that miR-4687-5p may be indicative of the susceptibility of Mtb infection to humans and could act as a potential therapeutic target for tuberculosis treatment.
2

Auguet, M., C. Favre-Guilmard, H. Zeroual-Hider, G. Prevost, and P. E. Chabrier. "332 SYNERGISTIC ANALGESIC INTERACTION BETWEEN MORPHINE AND BIM-46187." European Journal of Pain 10, S1 (September 2006): S89. http://dx.doi.org/10.1016/s1090-3801(06)60335-2.

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3

Levy, Michael J., Joseph E. Geenen, Marc F. Catalano, Michael J. Schmalz, Dan J. Geenen, and Walter J. Hogan. "4687 Pancreatic duct stent therapy for “smoldering” pancreatitis." Gastrointestinal Endoscopy 51, no. 4 (April 2000): AB203. http://dx.doi.org/10.1016/s0016-5107(00)14534-1.

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4

Favre-Guilmard, C., H. Zeroual-Hider, C. Soulard, G. Prevost, P. E. Chabrier, and M. Auguet. "333 THE NEW ANTICANCER AGENT BIM-46187 ELICITS ANALGESIC PROPERTIES." European Journal of Pain 10, S1 (September 2006): S89a—S89. http://dx.doi.org/10.1016/s1090-3801(06)60336-4.

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5

Pastrana V., Iván, Sony Reza G., Manuel Espinosa C., Emiro Suárez P, and Eliecer Díaz A. "Efecto de la fertilización nitrogenada en la dinámica del óxido nitroso y metano en Brachiaria humidicola (Rendle) Schweickerdt." Corpoica Ciencia y Tecnología Agropecuaria 12, no. 2 (November 23, 2011): 134. http://dx.doi.org/10.21930/rcta.vol12_num2_art:223.

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<p>Las actividades ganaderas causan un impacto significativo en los cambios ambientales, debido a las altas pérdidas de N que promueven procesos de nitrificación y aumento en emisiones de gases efecto invernadero (GEI). En el Centro de Investigación Turipaná de Corpoica (Cereté, Colombia), se evaluaron tres accesiones de B. humidicola (CIAT 16888, CIAT 26159 y CIAT 679) con tres niveles de aplicación de nitrógeno (0, 150 y 300 kg ha-1) con el fin de determinar la dinámica del flujo de gases de efecto invernadero y su relación con el crecimiento y la producción de forraje. Los resultados indicaron que el mejor genotipo, en términos de producción, fue CIAT 16888, con una producción de materia seca 2.075,32 kg ha-1, altura de 46,87 cm y relación hoja/tallo de 2,51, sin diferencias significativas con el genotipo CIAT 679 pero sí con el genotipo CIAT 26159 (P ≤ 0,05). El flujo de gases de efecto invernadero (metano y óxido nitroso) se incrementó con los niveles de N, lo que indica una correlación significativa entre el crecimiento del pasto y los flujos totales.</p><p> </p><p><strong>Effect of nitrogen fertilization on nitrous oxide and methane dynamics in Brachiaria humidicola (Rendle) Schweickerdt.</strong><strong></strong></p><p>Livestock activities cause a significant impact on the environment due to the release of N into the soil, which in turn results in nitrification and the emissions of greenhouse gases (GHG). At Corpoica’s Turipaná Research Center (Cereté, Colombia), we evaluated three different genotypes of B. humidicola (CIAT 16888, CIAT 26159, and CIAT 679) with three levels of nitrogen fertilization application (0, 150, and 300 kg ha-1) in order to determine the flow dynamics of GHG and their relationship to growth and forage production. The results indicated that the best genotype, in terms of production, was CIAT 16888, with an dry matter production of 2,075.32 kg ha-1, a height of 46.87 cm, and leaf/stem ratio of 2.51, with no significant differences with genotype CIAT 679, but with genotype CIAT 26159 (P ≤ 0.05). The flow of GHG (methane and nitrous oxide) increased as the N levels increased, indicating a significant correlation between the grass’s growth and total flows.</p>
6

Farsi, Carla. "SOFT C*-ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 45, no. 1 (February 2002): 59–65. http://dx.doi.org/10.1017/s0013091500000547.

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AbstractIn this paper we consider soft group and crossed product $C^*$-algebras. In particular we show that soft crossed product $C^*$-algebras are isomorphic to classical crossed product $C^*$-algebras. We also prove that large classes of soft $C^*$-algebras have stable rank equal to infinity.AMS 2000 Mathematics subject classification: Primary 46L80; 46L55
7

Surridge, Sian. "Book Mark: Occupational Therapy Evidence in Practice for Physical Rehabilitation (2006)." Canadian Journal of Occupational Therapy 75, no. 4 (October 2008): 229. http://dx.doi.org/10.1177/000841740807500409.

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Occupational Therapy Evidence in Practice for Physical Rehabilitation (2006) Lois Addy (Ed) Blackwell Publishing Ltd., 9600 Garsington Road, Oxford, OX4 2DQ, UK, 257 pages; 26.99 pounds, ISBN: 978-1-4051-4687-6
8

Weigert, Roberto, Maria Giuseppina Silletta, Stefania Spanò, Gabriele Turacchio, Claudia Cericola, Antonino Colanzi, Silvia Senatore, et al. "CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid." Nature 402, no. 6760 (November 1999): 429–33. http://dx.doi.org/10.1038/46587.

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9

Hunter, Alison F. "Diversity in the world of bugs." Nature 401, no. 6752 (September 1999): 428. http://dx.doi.org/10.1038/46687.

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10

Lestari, Happy Budi, and David Laksamana Caesar. "EFEKTIVITAS GRADASI WARNA KUNING SEBAGAI ATRAKTAN FLY GRILL." Jurnal Kesehatan Masyarakat Indonesia 14, no. 1 (May 31, 2019): 20. http://dx.doi.org/10.26714/jkmi.v14i1.4793.

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Latar Belakang: Beberapa jenis spesies lalat berperan dalam masalah kesehatan lingkungan dan kesehatan manusia yang salah satunya berupa diare. Lalat tidak dapat diberantas habis tetapi dapat dikendalikan sampai dengan batas yang tidak membahayakan atau menimbulkan masalah bagi kesehatan masyarakat. Cara yang paling mudah dan cepat untuk mengukur tingkat kepadatan lalat yaitu dengan menggunakan fly grill. Fly grill merupakan alat berupa potongan kayu yang disusun untuk melakukan survei kepadatan lalat. Tujuan penelitian ini adalah untuk mengetahui efektivitas warna kuning fly grill dalam menarik lalat. Metode: Penelitian ini dilakukan di TPS Pasar Jepang. Metode dalam penelitian ini menggunakan metode eksperimen dengan desain Posttest Only Design. Sampel yang digunakan dalam penelitian ini menggunakan teknik sampling jenuh yang artinya semua anggota populasi dijadikan sampel. Analisa data dalam penelitian ini menggunakan uji One Way Annova. Hasil: Persentase lalat yang hinggap pada warna kuning muda sebanyak 15,16%, warna kuning kenari sebanyak 46,87% dan warna kuning tua sebanyak 37,96%. Berdasarkan uji statistik menunjukan terdapat perbedaan efektivitas warna kuning fly grill dalam menarik lalat (p=0.0001). Kesimpulan: Fly grill warna kuning kenari efektif dalam menarik lalat karena mampu menarik lalat untuk hinggap sebanyak 46,87%.
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Статті в журналах Дисертації Книги

Дисертації з теми "46L87":

1

Zeng, Kai. "Some problems in harmonic analysis on twsited crossed products." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2023. http://www.theses.fr/2023UBFCD048.

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Cette thèse a pour but d’étudier quelques problèmes dans l'analyse harmonique sur les produits croisés tordus qui sont définis par des actions tordues d'un groupe localement compact G sur une algèbre de von Neumann M. Elle se compose de deux parties. La première porte sur les produits croisés tordus et leurs multiplicateurs de Fourier et de Schur. Nous démontrons que la propriété d’être QWEP pour l’algèbre de von Neumann tordue d’un groupe G est indépendante du 2-cocycle sous-ajacent et que les Lp-multiplicateurs de Fourier complètement bornés sur cette algèbre tordue sont aussi indépendants du 2-cocycle. Sous l’hypothèse d’une action moyennable, nous établissons plusieurs résultats de transfert entre les multiplicateurs de Fourier et de Schur sur les espaces Lp non-commutatifs du produit croisé tordu.Dans la deuxième partie, nous étudions les commutateurs de multiplicateurs de Fourier sur le produit croisé tordu d’un espace euclidien. Nous caractérisons leur appartenance à la p-classes de Schatten par celle de leurs symboles à un espace de Besov associé. Cette partie contient aussi une formule sur la trace de Dixmier qui nous donne également une caractérisation de l’appartenance de ces commutateurs à une p-classe de Schatten faible par un espace de Sobolev. En particulier, nos résultats s'appliquent au cas d’un espace euclidien quantique
This thesis is devoted to the study of some problems in the harmonic analysis on twisted crossed products defined by twisted actions of a locally compact group G on a von Neumann algebra M. It consists of two parts. The first concerns twisted crossed products and their Fourier and Schur multipliers. We prove that the property of being QWEP for the twisted von Neumann algebra of a group G is independent of the underlying 2-cocycle and that the completely bounded Lp-Fourier multipliers on this twisted algebra are also independent of the 2-cocycle. Under the hypothesis of an amenable action, we establish several transference results between the Fourier and Schur multipliers on the noncommutative Lp spaces of the twisted crossed product.In the second part, we study Fourier multiplier commutators on the twisted crossed product of an Euclidean space. We characterize their Schatten p-class membership by that of their symbols in the associated Besov space. In addition, this part contains a formula on the Dixmier trace, which also gives us a characterization of the weak Schatten p-class membership of these commutators by a Sobolev space. In particular, our results apply to the case of quantum Euclidean spaces
2

Thomas, Michael. "Same-sex marriage, civil partnerships and stigma : coming in from the cold?" Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/46287/.

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This thesis presents a cross-national, comparative study of legal recognition for lesbian and gay couples, focusing on civil partnerships in the UK and marriage in Canada and the US State of California. The study investigates the impact of same-sex marriage and civil partnership from the perspectives of lesbian and gay couples and, in particular, addresses the social implications of couples’ new legal status. The thesis investigates the impact of marriage or civil partnership within couples’ family and friendship networks and in a range of less intimate social contexts, including the workplace, the neighbourhood and commercial settings. The thesis also analyses the impact of legal recognition on couples’ sense of citizenship and assesses the effects of the Proposition 8 referendum, which repealed existing same-sex marriage rights in California in 2008. Drawing on qualitative data gathered from in-depth interviews with married or civil partner same-sex couples in the UK, Canada and California, the study analyses couples’ narratives around legal recognition to identify the meanings they attach to their new legal status. In the context of the wider policy objectives of legal recognition with regard to tackling discrimination and acknowledging same-sex couples within family and other social networks, the thesis applies Erving Goffman’s analysis of stigma to this evolving policy context. The study concludes that couples broadly welcomed the legal entitlements that flowed from marriage or civil partnership, and often saw legal recognition as providing opportunities to seek social recognition from within their personal networks. However, legal recognition did not in itself guarantee social recognition, and sometimes revealed the continuing marginalisation of lesbian and gay couples within family networks and in other social settings. This highlights a distinction between legal and social recognition, and points towards a significant gap between the policy ambitions attached to marriage and civil partnership and their micro-social impact.
3

Burgess, Katy V. "Associative analyses of reasoning-like behaviour in rats." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/46487/.

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This thesis examines how rats represent relationships in their environment. There are currently two broad classes of account of how animals learn about such relationships: The associative account offers a relatively simple mechanistic account of behaviour; while the second account proposes that animal behaviour, like human behaviour, is underpinned by the processes of causal and deductive reasoning, that are beyond associative analyses. Chapter 1 identifies three domains in which these two classes of account provide quite different analyses of animal behaviour, which are experimentally investigated in Chapters 2, 3 and 4. Chapter 2 reports three experiments that investigated the accuracy of predictions derived from the claim that rats are capable of forming and using causal models involving their own interactions with their environment (interventions) and external events (Blaisdell, Sawa, Leising, & Waldmann, 2006). The results failed to confirm these predictions and were instead more consistent with the operation of simpler processes. The results from Chapter 2 left open two interpretations: either rats can represent causality but do not use such representations to reason, or they do not represent cause per se. Chapter 3 investigated these alternatives in three experiments using a timing task, which should be sensitive to whether rats are more likely to represent their actions as causal than external events (Buehner & Humphreys, 2009). The results provided no support for the view that causal binding occurs in rats. Chapter 3 examined the possibility that sensory preconditioning might reflect a form of deductive reasoning (Hall, 1990). However, taken together, the results from four experiments provided no support for such an analysis; but instead helped to inform the nature of the associative processes that underlie sensory preconditioning. In summary, while the results reported in this thesis provide no support for analyses of animal behaviour that rely on the processes of causal or deductive reasoning, they do help to inform the nature of the associative processes involved.
4

Taghavi, N. "Facing the conflicts and complicities between capitalist modernisation and Islamisation : a study of women's subjectivities and emancipatory struggles in Iran." Thesis, University of Salford, 2018. http://usir.salford.ac.uk/46387/.

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This thesis is concerned with understanding women’s emancipatory struggles and efforts to challenge their secondary status in Iran, but with reference to other Muslim societies in the Middle East. To explore the possibility of women’s emancipation in Iran, the thesis focuses on, firstly, the position of women in relation to the forces of capitalist modernisation and Islamisation; secondly and more importantly, on women’s main convictions and inner-conflicts, and how these are shaped by those forces. The thesis thus seeks to grasp the structure and dynamics of women’s subjective field and to identify distinct subjective patterns which would constitute different responses to their situation. The thesis is divided into two parts: first, a literature review throws light on different crucial aspects of women’s lives and possibilities for transformation in Iran and other Muslim societies in relation to the forces of capitalist modernisation and Islamisation. While showing the richness and growing sophistications of an expanding field of study, the literature review also pointed out to a few significant lacunae or gaps in current research. Two such gaps stand out and are of the greatest relevance for this thesis, namely, the fact that the issues of women’s emancipation and subjectivities are missing in most studies of Muslim women, as these studies tend to overwhelmingly focus on women’s (often imposed rather than self-attributed) identities and on the anti-Western or anti-Islamic aspects thereof. The second part of this thesis, a field study, seeks to fill in some of those gaps, particularly those concerning women’s subjectivities and struggles for emancipation. In-depth semi-structured open-ended interviews with twenty-two Iranian women in Tehran from different social classes and backgrounds were conducted. The interviews, based on an interview guide designed so as to capture crucial aspects of women’s subjective dispositions and strivings for emancipation, immediately brought out the critical importance of the opposition, missing in most studies, between capitalism and emancipation, and enabled the development of a two-dimensional framework based on two central oppositions: capitalism vs. emancipation on the horizontal axis or dimension, and modernity vs. tradition on the vertical one. A more in-depth analysis of the interviews through the lens of the new framework allowed the identification of four main subjectivities carried by women and explain their emergence in terms of interaction effects between the four subjective determinations defining the framework (capitalism, modernity, emancipation and tradition): Islamist subjectivity, a statist form of religion in strong opposition to emancipatory feminism, the subjectivity of desire for the West, a fascination for individualism and a Western lifestyle and a denial of tradition, traditionalist subjectivities, a strong tendency to preserve all forms of traditions particularly religion and nationalism, and emancipatory subjectivity, although the latter only appears in this study in the form of modern emancipatory aspects and elements (with equality at their core) rather than a full-fledged ‘emancipatory subjectivity’. Thanks to this form of analysis we have come to understand that women’s movements in Iran are more oriented towards ‘tackling Islamisation’ than ‘seeking equality’ or ‘challenging patriarchy’. It is on this basis that the thesis draws two of its main conclusions: firstly, that the opposition between capitalism and emancipation should be not only taken into account, but a major basis for any future studies on Muslim women; and, secondly, that the struggle against Islamisation cannot be separated from the struggles against social inequality and patriarchy.
5

Schmitz, Anna-Lena [Verfasser]. "Novel insights into mechanisms and selectivity of the heterotrimeric G protein inhibitors BIM-46187 and FR900359 / Anna-Lena Schmitz." Bonn : Universitäts- und Landesbibliothek Bonn, 2015. http://d-nb.info/1101575689/34.

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6

Reeve, Jonathan Mark. "Learning algorithms for the control of routing in integrated service communication networks." Thesis, Durham University, 1998. http://etheses.dur.ac.uk/4687/.

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There is a high degree of uncertainty regarding the nature of traffic on future integrated service networks. This uncertainty motivates the use of adaptive resource allocation policies that can take advantage of the statistical fluctuations in the traffic demands. The adaptive control mechanisms must be 'lightweight', in terms of their overheads, and scale to potentially large networks with many traffic flows. Adaptive routing is one form of adaptive resource allocation, and this thesis considers the application of Stochastic Learning Automata (SLA) for distributed, lightweight adaptive routing in future integrated service communication networks. The thesis begins with a broad critical review of the use of Artificial Intelligence (AI) techniques applied to the control of communication networks. Detailed simulation models of integrated service networks are then constructed, and learning automata based routing is compared with traditional techniques on large scale networks. Learning automata are examined for the 'Quality-of-Service' (QoS) routing problem in realistic network topologies, where flows may be routed in the network subject to multiple QoS metrics, such as bandwidth and delay. It is found that learning automata based routing gives considerable blocking probability improvements over shortest path routing, despite only using local connectivity information and a simple probabilistic updating strategy. Furthermore, automata are considered for routing in more complex environments spanning issues such as multi-rate traffic, trunk reservation, routing over multiple domains, routing in high bandwidth-delay product networks and the use of learning automata as a background learning process. Automata are also examined for routing of both 'real-time' and 'non-real-time' traffics in an integrated traffic environment, where the non-real-time traffic has access to the bandwidth 'left over' by the real-time traffic. It is found that adopting learning automata for the routing of the real-time traffic may improve the performance to both real and non-real-time traffics under certain conditions. In addition, it is found that one set of learning automata may route both traffic types satisfactorily. Automata are considered for the routing of multicast connections in receiver-oriented, dynamic environments, where receivers may join and leave the multicast sessions dynamically. Automata are shown to be able to minimise the average delay or the total cost of the resulting trees using the appropriate feedback from the environment. Automata provide a distributed solution to the dynamic multicast problem, requiring purely local connectivity information and a simple updating strategy. Finally, automata are considered for the routing of multicast connections that require QoS guarantees, again in receiver-oriented dynamic environments. It is found that the distributed application of learning automata leads to considerably lower blocking probabilities than a shortest path tree approach, due to a combination of load balancing and minimum cost behaviour.
7

Katikireddi, Srinivasa Vittal. "The relationship between evidence and public health policy : case studies of the English public health white paper and minimum unit pricing of alcohol in Scotland." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4687/.

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Background: Public health researchers and practitioners have repeatedly called for policy to be informed by academic evidence. The rise of the evidence-based medicine movement has demonstrated the potential benefits of using evidence for clinical decision-making. Recently, politicians and policy documents have echoed these calls for increased use of evidence in policymaking by drawing upon the discourse of evidence-based policy. However, efforts to understand the relationship between evidence and public health policy are underdeveloped and often make limited use of knowledge from other fields, including political science and sociology. This thesis aims to explore the relationship between evidence and public health policy in the UK using two contemporary case studies: the English public health White Paper, ‘Healthy Lives, Healthy People’; and the development of minimum unit pricing of alcohol in Scotland. Methods: The first case study: ‘Healthy Lives, Healthy People’ case study investigates the extent that three prominent discourses that draw upon academic work are reflected by the policy statements contained within the White Paper. The three areas examined include evidence on ‘what works’, the Nuffield framework on public health ethics and insights from behavioural science (‘nudge’). These discourses were chosen as they are not only rhetorically prominent in the White Paper, but also because they reflect the range of direct use of specific research findings and more conceptual use of research-derived ideas. To examine the extent that evidence on ‘what works’ has been incorporated into ‘Healthy Lives, Healthy People’, the research evidence for each of 51 specific policy actions described in the White Paper was reviewed. A critical analysis of ‘nudge’ and the Nuffield framework was conducted by contrasting their application with the authors’ original articulation. The second case study explores the development of the high-profile public health policy of minimum unit pricing of alcohol by drawing upon three different sources of data. First, a review of policy documents was conducted. Second, a systematic document analysis of evidence submissions that were received by the Scottish Parliament’s Health and Sport Committee in response to its consultation on minimum unit pricing was performed. This analysis drew specifically on a framework for analysing political argumentation. Third, 36 semi-structured interviews were carried out with a broad range of policy stakeholders. Interviewees were purposively chosen to obtain diversity in supportiveness for minimum unit pricing, as well as by professional position (academic, advocate, civil servant, politician, industry representative). The evidence submissions and interview data were thematically coded and organised using NVivo 9. Results: By systematically assessing the evidence underpinning the English public health White Paper, the study empirically established that public health policy does not meet conventional public health standards for being evidence-based. Similarly, the prominence of ‘nudge’ and the Nuffield framework in the text of ‘Healthy Lives, Healthy People’ do not appear to be matched by the actions suggested. However, this first case study finds that while evidence does have an influence, it does not determine policy. This relationship appears complex, partial and contingent rather than direct and instrumental, therefore necessitating a more detailed and focused case study. The second case study begins by providing a detailed description of the process by which minimum unit pricing developed in Scotland. It then draws on the analysis of evidence submission documents combined with interview data to identify a crucial role of public health advocates, who reframed the alcohol policy debate to bring about policy change. Epidemiological concepts were important in helping to achieve this shift in policy framing. Having investigated more conceptual influences of evidence, econometric modelling carried out by a team at the University of Sheffield is focused on as an example of a specific piece of research evidence that was perceived by interviewees to be influential in the policy debate. The different types of influence that the modelling study had on the policy process are determined and reasons for its influence investigated. The study also finds that interviewees believed econometric modelling could be more widely used to inform future public health policymaking. Lastly, a ‘multiple lenses’ approach builds upon these findings and political science theory to produce a comprehensive explanation of the policy process and describe the roles of evidence on the minimum unit pricing policy process. Discussion: Analysis of the ‘Healthy Lives, Healthy People’ White Paper shows that despite the prominent rhetoric for evidence-based policy, this is not reflected by the reality of current public health policy in the UK. The investigation of the development of minimum unit pricing of alcohol in Scotland demonstrates that evidence influences the policy process in a number of ways but these influences are heavily context-dependent. The role of evidence in changing the framing of the policy debate has been identified as of particular importance for this case study. The devolution process and evolving nature of political institutions also raises particular opportunities, but also challenges, for public health professionals. The strengths of the thesis include its use of two case studies to investigate the relationship between evidence and public health policy, the analysis of multiple sources of data in relation to minimum unit pricing policy and the application of political science theories that are typically underused in public health research. Limitations include the caution required when making generalisations from these data, particularly since these case studies have been purposively chosen. Drawing upon the two case studies, a conceptual model for the relationship between evidence and public health policy is articulated. The model suggests that evidence is likely to be used in different ways depending on the extent that the political values underpinning an issue are contested, with the importance of evidence for rhetorical purposes being a legitimate and helpful means of highlighting the health aspects of public policy issues. Lessons for public health researchers and practitioners, as well as directions for future research and theoretical implications, are considered and discussed.
8

Berardi, Giuseppe. "Caratterizzazione neurofisiologica e analisi del segnale neuronale dopaminergico in un modello animale di schizofrenia." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4687/.

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9

Biller, Patrick. "Hydrothermal processing of microalgae." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/4687/.

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Microalgae are regarded as a promising biomass resource for the production of biofuels and chemicals which does not compete with food production. Microalgae contain large amounts of lipids and have faster growth rates than terrestrial biomass. One of the current technological bottlenecks of biofuels conversion is the economic extraction and processing of microalgae components. Due to their aquatic nature microalgae contain large amounts of water when harvested. Hydrothermal liquefaction (HTL) involves processing the algae as a slurry in hot compressed water, avoiding drying of the wet feedstock. This is a major energy benefit compared to dry microalgae processing methods. A detailed characterisation of the microalgae feedstocks investigated for the current work is provided. The main differences between marine, fresh water and cyanobacteria strains are presented. The microalgae strains are investigated for biochemical composition, proximate and ultimate analysis, thermo-gravimetrical analysis, pyrolysis GC-MS, metal content, pigment analysis and by scanning electron microscopy. The results from the characterisation work are employed throughout the thesis for mass balance calculations and investigation of reaction chemistry. HTL for bio-crude production is investigated both on laboratory batch systems and a continuous pilot scale facility. Processing at mild conditions results in mainly the lipids of microalgae being extracted resulting in a high quality bio-crude. Higher temperatures are shown to result in higher yields of bio-crude as carbohydrates and proteins increasingly contribute to bio-crude formation. This allows processing of low lipid containing microalgae which are associated with higher growth rates. Maximum bio-crude yields of around 50 wt.% can be achieved but can contain significant amounts of nitrogen and oxygen. A total of 11 microalgae strains is investigated leading to an average bio-crude yield of 34 %, a heating value of 36 MJ/kg, a nitrogen content of 4.7 wt.% and an oxygen content of 13.6 wt.%. The use of homogeneous and heterogeneous catalysts is investigated to increase bio-crude quality and yields. Model compounds of protein, lipid and carbohydrates are processed individually to shed light on the HTL behaviour of microalgae components and the reaction pathways involved in bio-crude formation. The effect of sodium carbonate and formic acid as homogeneous catalysts is investigated on various microalgae strains with changing biochemical composition and on model compounds separately. It is shown that biochemical components of microalgae behave additively in respect to bio-crude formation. The trends of bio-crude formation follow lipids>protein>carbohydrates. It is further shown that carbohydrates are best processed in alkali conditions while protein and lipids are best processed without the use of catalysts. The same effect is demonstrated for algae high in carbohydrates or proteins and lipids respectively. Heterogeneous catalysts are shown not to increase the bio-crude significantly but result in additional decarboxylation of the bio-crude to reduce the oxygen level by a further 10%. The process water composition from HTL is investigated for common nutrients required for algae cultivation. It is shown that nutrients are present in higher concentrations than comparable standard algae growth media. The process water also contains large amounts of organic carbon which is considered a loss, unavailable for bio-crude formation. Growth trials in dilutions of the process water to grow fresh algae demonstrate that growth is sustainable. The organic carbon in the process water is shown to act as a substrate for mixotrophic growth resulting in increased growth rates and carbon efficiency. For analysis of the algae obtained from small scale growth trials a new analysis technique for microalgae composition analysis is introduced. This involves Py-GC-MS of model compounds and comparisons to algae pyrolysis products. Promising results are presented, showing the feasibility of detecting protein, carbohydrate and lipid levels of microalgae directly from growth cultures. Additionally the methodology is expanded to detect phytochemical concentrations such as astaxanthin and chlorophyll a. An alternative to direct hydrothermal liquefaction involving removal of valuable compounds from microalgae by hydrothermal microwave processing (HMP) is investigated. HMP is shown to remove protein and large amounts of nutrients from the algae biomass which could be used as a source of nutrients for microalgae cultivation. The cells walls are shown to be disrupted, leading to increased recovery of lipids by solvent extraction while the lipids‟ degree of saturation is not affected. This allows effective extraction of high value poly-unsaturated fatty acids. The residue form HMP is processed using flash pyrolysis and HTL for bio-crude production. The results show that bio-crudes of increased quality are produced. The technique appears especially suitable for marine microalgae strains as the salt content acts as microwave absorbers, reducing energy consumption and increasing reaction rates. Overall, the experimental work shows that hydrothermal processing is a low energy intensive wet processing technique for microalgae to produce bio-fuels and chemicals.
10

Edwards, Alison A. "Tetrahydrofuran based sugar amino acids as foldamers and library scaffolds." Thesis, University of Kent, 2003. https://kar.kent.ac.uk/4687/.

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Sugar amino acids (SAAs) have been extensively prepared in literature and utilised as dipeptide isosteres. The secondary structural preferences of delta-amino acids based upon tetrahydrofuran (THF) rings were ascertained by study of the corresponding homooligomers. Many of these were found to exhibit compact secondary structures (such as a repeating beta-turn and a left-handed 16-helix) in short sequences - foldamers. Pyranose SAAs have also been utilised as library scaffolds. Chapter 2 describes the preparation of simplified delta-amino acid analogues of the existing SAA systems that adopt rigid secondary structures. Removal of the hydroxyl function at C-3 of L-gulonolactone and D-mannonolactone prior to THF formation gave efficient access to 3-deoxy THFs. The deoxygenated THFs of D-ribo and L-lyxo stereochemistry were utilised to provide access to the desired D-ribo, L-arabino and L-lyxo delta-amino acid precursors which contained the acid and amine functions orthogonally protected as an ester and azide respectively. Selective deprotection with solution phase coupling afforded the desired homooligomers. Information regarding the secondary structural preferences of these homooligomers was obtained by NMR (nOe, DMSO titrations, H/D exchange and variable temperature experiments), by solution IR and by circular dichroism (CD). The homooligomers were prepared in both protected and unprotected forms and two types of hydroxyl protection (silyl and acetyl) employed to allow investigation of any effects arising from different solvents and protecting groups. The homooligomers of the delta-amino acids with the 2,5-cis relationship adopted intramolecularly hydrogen bonded structures (by NMR and solution IR) which contained the nOes characteristic for the repeating beta-turn conformation. The removal of the hydroxyl function at C-3, the use of different solvents and different protecting groups did not perturb the conformation adopted by the 2,5-cis 3-deoxy homoligomers. By contrast, the 2,5-trans homooligomers did not adopt hydrogen bonded secondary structures (by solution IR) although poor signal dispersion by NMR restricted nOe study of the tetramers. CD spectra (in both TFE and water) showed that despite the absence of hydrogen bonding, a rigid conformation could be adopted by these homooligomers which was favoured when the bulky triethylsilyl group was present. In chapter 3, the 3-deoxy D-ribo and L-lyxo THFs were utilised to prepare D-xylo, L-arabino and L-lyxo gamma-amino acids based on the 3-deoxy THF scaffold. Subsequent preparation of the corresponding unprotected and triethylsilyl protected tetramers allowed investigation of the secondary structural preferences of the cyclically rigidified gamma-amino acid homooligomers. No evidence was obtained for the formation of hydrogen bonded secondary structures. However, the observed dispersion of the amide protons of the protected oligomers in CDCl3, the presence of a broad peak by solution IR and partial rigidity by CD (in both TFE and water) lends hope that the formation of longer oligomers may lead to the formation of rigid structures, although not necessarily stabilised by hydrogen bonding interactions. The L-lyxo and L-arabino TBDPS protected azides were validated as library scaffolds. Due to time restrictions only the L-lyxo azide was used as a scaffold and a 99-member library was successfully prepared. The library was screened for antimicrobial activity. Subsequent analysis of the five active library members showed that the active compounds were not the library members but impurities. A possible reaction side product was proposed but despite further testing of this compound (and several analogues), the compound(s) responsible for the biological activity were not identified.
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Книги з теми "46L87":

1

United States. Congress. House. Committee on Rules. National Construction Safety Team Act: Report (to accompany H.R. 4687) (including cost estimate of the Congressional Budget Office). [Washington, D.C: U.S. G.P.O., 2002.

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2

Renaville, R., and A. Burny, eds. Biotechnology in Animal Husbandry. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/0-306-46887-5.

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3

Leibe, Bastian, Jiri Matas, Nicu Sebe, and Max Welling, eds. Computer Vision – ECCV 2016. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-46487-9.

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4

Hirose, Akira, Seiichi Ozawa, Kenji Doya, Kazushi Ikeda, Minho Lee, and Derong Liu, eds. Neural Information Processing. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-46687-3.

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5

Michette, Alan G., Graeme R. Morrison, and Chistopher J. Buckley, eds. X-Ray Microscopy III. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-540-46887-5.

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6

Vidal, René V. V., ed. Applied Simulated Annealing. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5.

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7

Theurillat, Michael J. Der Schweizer Aktienmarkt. Heidelberg: Physica-Verlag HD, 1996. http://dx.doi.org/10.1007/978-3-642-46987-9.

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8

Brandt, Siegmund, and Hans Dieter Dahmen. Quantenmechanik in Bildern. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-46387-1.

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9

Han, Seung-Kyu. Innovations and Advances in Wound Healing. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46587-5.

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10

Woernle, Christoph. Mehrkörpersysteme. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46687-2.

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Частини книг з теми "46L87":

1

Remacle, C., L. De Clercq, J. Mourot, and C. Boone. "Anti-Adipocyte Monoclonal Antibodies: A New Technology for Regulating Adipose Conversion." In Focus on Biotechnology, 159–67. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/0-306-46887-5_9.

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2

Vidal, René V. V. "Introduction." In Lecture Notes in Economics and Mathematical Systems, 1–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_1.

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3

Andersen, Klaus, René Victor Valqui Vidal, and Villy Bæk Iversen. "Design of a Teleprocessing Communication Network Using Simulated Annealing." In Lecture Notes in Economics and Mathematical Systems, 201–15. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_10.

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4

Hansen, Torben Dyhr. "Location of Civil Defence Sirens." In Lecture Notes in Economics and Mathematical Systems, 217–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_11.

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5

Vidal, Renè Victor Valqui. "Solving the Afforestation Problem." In Lecture Notes in Economics and Mathematical Systems, 239–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_12.

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6

Oliveira, José Fernando C., and José A. Soeiro Ferreira. "Algorithms for Nesting Problems." In Lecture Notes in Economics and Mathematical Systems, 255–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_13.

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7

Liégeois, B., M. Pirlot, J. Teghem, E. Trauwaert, and D. Tuyttens. "Balanced Grouping through Simulated Annealing." In Lecture Notes in Economics and Mathematical Systems, 275–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_14.

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8

Vidal, René Victor Valqui. "Optimal Partition of an Interval — The Discrete Version." In Lecture Notes in Economics and Mathematical Systems, 291–312. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_15.

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9

Olsson, Carsten Kruse. "Simulated Annealing in Image Processing." In Lecture Notes in Economics and Mathematical Systems, 313–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_16.

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10

Iversen, V. B., J. M. Rygaard, and R. V. V. Vidal. "Optimal Pallet Capacity For A FMS." In Lecture Notes in Economics and Mathematical Systems, 335–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-46787-5_17.

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Тези доповідей конференцій з теми "46L87":

1

Mukherjee, Arpan, Rahul Rai, Puneet Singla, Tarunraj Singh, and Abani Patra. "Non-Negative Matrix Factorization Based Uncertainty Quantification Method for Complex Networked Systems." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46087.

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The behavior of large networked systems with underlying complex nonlinear dynamic are hard to predict. With increasing number of states, the problem becomes even harder. Quantifying uncertainty in such systems by conventional methods requires high computational time and the accuracy obtained in estimating the state variables can also be low. This paper presents a novel computational Uncertainty Quantifying (UQ) method for complex networked systems. Our approach is to represent the complex systems as networks (graphs) whose nodes represent the dynamical units, and whose links stand for the interactions between them. First, we apply Non-negative Matrix Factorization (NMF) based decomposition method to partition the domain of the dynamical system into clusters, such that the inter-cluster interaction is minimized and the intra-cluster interaction is maximized. The decomposition method takes into account the dynamics of individual nodes to perform system decomposition. Initial validation results on two well-known dynamical systems have been performed. The validation results show that uncertainty propagation error quantified by RMS errors obtained through our algorithms are competitive or often better, compared to existing methods.
2

Joshi, Shreyash, and Bo Chen. "Modeling and Hardware-in-the-Loop Simulation of Power-Split Device for Hybrid Electric Vehicles." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46187.

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Conventional vehicles are creating pollution problems, global warming and the extinction of high density fuels. To address these problems, automotive companies and universities are researching on hybrid electric vehicles where two different power devices are used to propel a vehicle. This research studies the development and testing of a dynamic model for Prius 2010 Hybrid Synergy Drive (HSD), a power-split device. The device was modeled and integrated with a hybrid vehicle model. To add an electric only mode for vehicle propulsion, the hybrid synergy drive was modified by adding a clutch to carrier 1. The performance of the integrated vehicle model was tested with UDDS drive cycle using rule-based control strategy. The dSPACE Hardware-In-the-Loop (HIL) simulator was used for HIL simulation test. The HIL simulation result shows that the integration of developed HSD dynamic model with a hybrid vehicle model was successful.
3

Chen, Guimin, and Ruiyu Bai. "Modeling Large Spatial Deflections of Slender Bisymmetric Beams in Compliant Mechanisms Using Chained Spatial-Beam-Constraint-Model (CSBCM)." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46387.

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Modeling large spatial deflections of flexible beams has been one of the most challenging problems in the research community of compliant mechanisms. This work presents a method called chained spatial-beam-constraint-model (CSBCM) for modeling large spatial deflections of flexible bisymmetric beams in compliant mechanisms. CSBCM is based on the spatial beam constraint model (SBCM), which was developed for the purpose of accurately predicting the nonlinear constraint characteristics of bisymmetric spatial beams in their intermediate deflection range. CSBCM deals with large spatial deflections by dividing a spatial beam into several elements, modeling each element with SBCM, and then assembling the deflected elements using the transformation defined by Tait-Bryan angles to form the whole deflection. It is demonstrated that CSBCM is capable of solving various large spatial deflection problems whether the tip loads are known or the tip deflections are known. The examples show that CSBCM can accurately predict the large spatial deflections of flexible beams, as compared to the available nonlinear FEA results obtained by ANSYS. The results also demonstrated the unique capabilities of CSBCM to solve large spatial deflection problems that are outside the range of ANSYS.
4

Kahrobaiyan, M. H., I. Vardi, M. T. Ahmadian, and S. Henein. "Investigating the Size-Dependent Static and Dynamic Behavior of Circular Micro-Plates Subjected to Capillary Force." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46487.

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The size-dependent static deflection, pull-in instability and resonant frequency of a circular microplate under capillary force have been studied using modified couple stress elasticity theory. Size-dependency is a phenomenon in which the normalized quantities that classical elasticity theory predicts to be independent of the structure size, such as normalized deflection or normalized frequency, vary significantly as the structure size changes. This phenomenon has been observed in micro-scale structures such as micro-electro-mechanical-systems (MEMS). Since classical elasticity theory is unable to predict the size-dependency, non-classical elasticity theories such as modified couple stress theory have been developed recently. In this paper, modified couple stress theory is used for the first time to develop the governing equation and boundary conditions of circular microplates when subjected to capillary force. Consideration of capillary force is important since it is has a significant role in the mechanical behavior and stability of micro-scale structures in the presence of a liquid bridge. We investigated the static deflection and pull-in instability of microplates using the Galerkin method to assess the effect of size-dependency for static deflection. We observed that, as the ratio of the microplate thickness to length scale parameter (an additional material property suggested in modified couple stress theory to capture the size-dependency) decreases, the normalized deflection of the microplate also decreases. We further observed that the difference between the normalized deflection predicted by classical elasticity theory and the one evaluated using modified couple stress theory is significant when thickness of the microplate is small, but diminishes as thickness increases. Furthermore, we defined a dimensionless number called the dimensionless capillary tension (DCT) as a function of the mechanical, geometrical and size-dependent properties of the microplate as well as the characteristics of the liquid bridge such as the contact angle and the interfacial tension. We showed that for DCT values greater than a threshold evaluated in this paper, pull-in instability happens and the microplate collapses to the substrate. Moreover, we evaluated the size-dependent resonant frequency of the microplate under capillary force as a function of the DCT and obtained the result that the frequency decreases as DCT increases. In addition, our investigation of size-dependency revealed that as the ratio of the microplate thickness to length scale parameter increases, the frequency decreases in a way that for large values of the ratio, it asymptotically approaches the value predicted by classical elasticity theory.
5

Andulkar, Mayur V., and Shital S. Chiddarwar. "Automated CAD Based Trajectory for Spray Painting Robot: Variable Velocity Approach." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46587.

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This paper proposes a new automated offline trajectory generation approach for free form surfaces targeted towards spray painting application. The spray gun trajectory is generated from the computer aided design (CAD) model of the surface to be painted for a structured environment. A variable velocity approach is proposed to overcome the effect of surface curvature on the desired paint thickness. The proposed approach is divided into three problems: paint pass generation, optimal gun velocity and overlap distance computation. These problems are solved independently of each other using standard optimization techniques. The paint passes consisting of points and corresponding normals are generated using a ‘section’ based approach. An optimal variable spray gun velocity depending on the surface curvature is calculated based on the paint thickness function using genetic algorithm and curve fitting technique. The overlap distance is calculated depending on paint thickness of every paint pass. The approach was implemented on test surfaces and the simulation and experimental results reveal that minimal paint thickness deviation is obtained for simple as well as highly curved surfaces.
6

Pirmoradi, Zhila, and G. Gary Wang. "Sensitivity and Correlation Analysis and Implications in Scalable Product Family Design for Plug-In Hybrid Electric Vehicles." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46687.

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Plug-in Hybrid Electric Vehicles (PHEVs) bear great promises for increasing fuel economy and decreasing greenhouse gas emissions by the use of advanced battery technologies and green energy resources. The design of a PHEV highly depends on several factors such as the selected powertrain configuration, control strategy, sizes of drivetrain components, expected range for propulsion purely by electric energy, known as AER, and the assumed driving conditions. Accordingly, design of PHEV powertrains for diverse customer segments requires thorough consideration of the market needs and the specific performance expectations of each segment. From the manufacturing perspective, these parameters provide the opportunity of mass customization because of the high degree of freedom, especially when the component sizes and control parameters are simultaneously assessed. Based on a nonconventional sensitivity and correlation analysis performed on a simulation model for power-split PHEVs in this study, the product family design (PFD) concept and its implications will be investigated, and limitations of PFD for such a complex product along with directions for efficient family design of PHEVs will be discussed.
7

Hogan, François Robert, James Richard Forbes, and Alex Walsh. "Dynamic Modeling of a Rolling Flexible Sphere." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46787.

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The motion equations of a rolling flexible spherical shell are derived using a Lagrangian formulation. The motion equations developed capture the nonholonomic nature of the flexible sphere rolling without slip on a flat surface. The free vibrations of the spherical shell are modeled using the Rayleigh-Ritz discretization method. Numerical simulations are performed to validate the dynamic model developed and to investigate the effect of the flexibility of the spherical shell on its trajectory.
8

Layeghi, Mohammad. "Analysis of Fluid Flow in Cylindrical Microchannels Subjected to Uniform Wall Injection." In ASME 2004 3rd Integrated Nanosystems Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/nano2004-46087.

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Analytical analysis of fluid flow in cylindrical microchannels subjected to uniform wall injection at various Reynolds numbers is presented. The classical Navier-Stokes equations are used in the present study. Mathematically, using an appropriate change of variable, Navier-Stokes equations are transformed to a set of nonlinear ordinary differential equations. The governing equations are solved analytically using series solution method. The presented analytical results can be used for the prediction of velocity profiles and pressure drops in the cylindrical micro channels. The results are validated against available data in the literature and have shown good agreement.
9

Ferrari, C., M. Pinelli, P. R. Spina, P. Bolognin, and L. Borghi. "Fluid Dynamic Design and Optimization of Two Stage Centrifugal Fan for Industrial Burners." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-46087.

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In this paper, the fluid dynamic design of a two-stage centrifugal fan for industrial burner application is presented. The design is carried out by means of an integrated 1D/3D numerical procedure based on the use of CFD simulations. The CFD simulations are used either at the preliminary design stage to choose among competitive one- or two-dimensional geometries and then to test the generated three-dimensional geometries. The results show how the different design choices could impact on the performance parameters and, finally, how the analysis of the various alternatives allows the determination of the overall geometry of a complete and performing two-stage centrifugal fan.
10

Kobayashi, M., H. Ogata, T. Oda, R. Matsuyama, A. Horikawa, Y. Kinoshita, and Hitoshi Fujiwara. "Improvement on Ignition Performance for a Lean Staged Low NOx Combustor." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-46187.

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KHI (Kawasaki heavy industries Ltd, Japan) and JAXA (Japan Aerospace Exploration Agency) have been working together since 2004 to improve lean staged concentric fuel injector technologies. One of the weak points of a lean staged fuel injector is said to be ignition / light around performance. Ignition characteristics were assessed on several fuel injector configurations in burner tests. Laser diagnosis, CFD analysis and high-speed video camera recording were used to understand the effect of fuel injector geometry on fuel spray distribution and ignition characteristics. They showed a clear relationship between the burner geometry and ignition characteristics. Light around characteristics was evaluated with the burner configuration optimized in burner tests. Light around performance deteriorated in multi sector unit compared to that in burner test. CFD analysis and some ignition tests with different configuration of combustor gave a clue to restore the light around characteristics deteriorated in multi sector unit.

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