Добірка наукової літератури з теми "Α/β Peptide"
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Статті в журналах з теми "Α/β Peptide"
Checco, James W., Dale F. Kreitler, Nicole C. Thomas, David G. Belair, Nicholas J. Rettko, William L. Murphy, Katrina T. Forest та Samuel H. Gellman. "Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold". Proceedings of the National Academy of Sciences 112, № 15 (30 березня 2015): 4552–57. http://dx.doi.org/10.1073/pnas.1420380112.
Повний текст джерелаOppegård, Camilla, Gunnar Fimland, Lisbeth Thorbæk, and Jon Nissen-Meyer. "Analysis of the Two-Peptide Bacteriocins Lactococcin G and Enterocin 1071 by Site-Directed Mutagenesis." Applied and Environmental Microbiology 73, no. 9 (March 2, 2007): 2931–38. http://dx.doi.org/10.1128/aem.02718-06.
Повний текст джерелаFox, Robert I., and Ho-Il Kang. "Mechanism of Action of Antimalarial Drugs: Inhibition of Antigen Processing and Presentation." Lupus 2, no. 1_suppl (February 1993): 9–12. http://dx.doi.org/10.1177/0961203393002001031.
Повний текст джерелаMaruthainar, K., Y. Peng-Loh та D. G. Smyth. "The processing of β-endorphin and α-melanotrophin in the pars intermedia of Xenopus laevis is influenced by background adaptation". Journal of Endocrinology 135, № 3 (грудень 1992): 469–78. http://dx.doi.org/10.1677/joe.0.1350469.
Повний текст джерелаClark, David C., Linda J. Smith та Lesley C. Chaplin. "The Effect of Dephosphorylation on the Conformation of Peptides from β-Casein". Collection of Czechoslovak Chemical Communications 57, № 2 (1992): 425–28. http://dx.doi.org/10.1135/cccc19920425.
Повний текст джерелаOlsen, Christian A., Gitte Bonke, Line Vedel, Anne Adsersen, Matthias Witt, Henrik Franzyk та Jerzy W. Jaroszewski. "α-Peptide/β-Peptoid Chimeras". Organic Letters 9, № 8 (квітень 2007): 1549–52. http://dx.doi.org/10.1021/ol070316c.
Повний текст джерелаYin, Hang, Hua Zhu, Gaston Vilaire, Wei Li, Rustem I. Litvinov, William F. DeGrado та Joel S. Bennett. "Activation of Platelet α Iibβ 3 by Exogenous Peptides Corresponding to the Transmembrane Domains of α Iib and β 3." Blood 106, № 11 (16 листопада 2005): 384. http://dx.doi.org/10.1182/blood.v106.11.384.384.
Повний текст джерелаBerlicki, Łukasz, Ludwig Pilsl, Edit Wéber, István M. Mándity, Chiara Cabrele, Tamás A. Martinek, Ferenc Fülöp та Oliver Reiser. "Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid". Angewandte Chemie International Edition 51, № 9 (26 січня 2012): 2208–12. http://dx.doi.org/10.1002/anie.201107702.
Повний текст джерелаJin, Yi, Janet Hammer, Michelle Pate, Yu Zhang, Fang Zhu, Erik Zmuda та Jack Blazyk. "Antimicrobial Activities and Structures of Two Linear Cationic Peptide Families with Various Amphipathic β-Sheet and α-Helical Potentials". Antimicrobial Agents and Chemotherapy 49, № 12 (грудень 2005): 4957–64. http://dx.doi.org/10.1128/aac.49.12.4957-4964.2005.
Повний текст джерелаLegrand, Baptiste, та Ludovic T. Maillard. "α,β‐Unsaturated γ‐Peptide Foldamers". ChemPlusChem 86, № 4 (квітень 2021): 629–45. http://dx.doi.org/10.1002/cplu.202100045.
Повний текст джерелаДисертації з теми "Α/β Peptide"
Das, Chittaranjan. "Designed β-Hairpin, β-Sheet And Mixed α-β Structures In Synthetic Peptides". Thesis, Indian Institute of Science, 2000. http://hdl.handle.net/2005/263.
Повний текст джерелаKil, Hyun Joo. "Design & Synthesis of Peptidomimetics Adopting Secondary Structures for Inhibition of p53/MDM2 Protein-protein Interaction and Multiple Myeloma Cell Adhesion." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5051.
Повний текст джерелаLopez-Perez, Elvira. "La voie α-sécrétase de maturation de la protéine précurseur du peptide β-amyloi͏̈de dans la maladie d'Alzheimer : activités protéolytiques et régulation". Nice, 2000. http://www.theses.fr/2000NICE5459.
Повний текст джерелаSaraiva, rosa Nathalie. "Synthèse diastéréosélective de molécules azotées α-trifluorométhylées - Élaboration et études conformationnelles de petits peptides incorporant des acides β-aminés trifluorométhylés". Thesis, Reims, 2017. http://www.theses.fr/2017REIMS013.
Повний текст джерелаChiral N-tert-butansulfinamides, developped by Ellman 20 years ago, have been increasingly applied for the preparation of chiral functionnalized amines, because of the affordability of both enantiomers and of their mild conditions of cleavage. However, the use of theses auxiliaries for the synthesis of quaternary trifluoromethyl derivatives remains quite limited, the corresponding trifluoromethyl ketoimines being highly unstable.Chiral N-tert-butanesulfinyl alkyl(aryl) trifluoromethyl hemiaminal ethers have been developped to be used as bench-stable surrogates of these ketoimines : once under reaction conditions, they afford the corresponding ketoimine in situ, which can be subject to a nucleophilic addition.In this manuscript, different reactions led on these hemiaminal ethers are described, affording valuable and optically pure trifluoromethylated quaternary building-blocks : on the one hand, homoallylic amines, obtained by the addition of allylalane species, and which can afford, after a few steps, teh corresponding trifluoromethyl azetidines, and on the other hand, chiral trifluoromethyl β3,3-amino acids, afforded by a highly diastereoselective Reformatsky reaction.These β 3,3-amino acids have been then involved in solution-phase peptide couplings in order to synthetise a wide range of α/β- and β-di- and tripeptides, whose conformation have been the object of preliminary studies in the solid state and/or in solution.Key-words : Ellman auxiliary, Nucleophilic addition, Solution-phase peptide coupling, α-trifluoromethylated nitrogen derivative, Hemiaminal ether, asymmetric synthesis
Attal, Sandra. "Utilisation des enzymes en chimie organique : application à la synthèse d'esters de dipeptides par la papai͏̈ne et de galactosyl-sérines par les α-et β-galactosidases". Paris 5, 1992. http://www.theses.fr/1992PA05P614.
Повний текст джерелаCollet, Magalie. "Peptidonucléoside polyoxine J, inhibiteur de la chitine synthase : approches vers la synthèse du nucléoside C2' - désoxy -C2' fluoré, et synthèse de l'acide 5-O-carbamoyle polyoxamique." Toulouse 3, 2004. http://www.theses.fr/2004TOU30198.
Повний текст джерелаPolyoxins, which form an important class of peptidyl nucleosidic antibiotics that selectively and competitively inhibit chitin synthase, are very active components in vitro, but weakly bioavailable in vivo. The subject of this thesis has been to found new synthetic methods to access to C2'-fluoro-C2'-deoxy analogues of thymine polyoxine C, nucleosidic part of polyoxine J (the more active one), and to obtain, by an original way, the non natural peptidic moiety of polyoxine J, which is the 5-O-carbamoyl polyoxamic acid. After a presentation of the biological target and the interest of the introduction of a fluorine atom, this work is divided into two parts. Fisrt, two approaches of the fluorinated nucleosodic part using 2-deoxy-2-fluorobutyrolactones as intermediates, and then, an optimization of the synthesis of the peptidic part using the formation of an oxazolidonone intermediate
Norgren, Anna S. "Conformational Stability!? : Synthesis and Conformational Studies of Unnatural Backbone Modified Peptides." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7420.
Повний текст джерелаPatino, Nadia. "Peptides fluorés : intérêt et synthèse de peptides incorporant dans leur structure un acide α-aminé β-fluoré". Nice, 1989. http://www.theses.fr/1989NICE4274.
Повний текст джерелаWillems, Hendrika Maria Gerarda. "The design and synthesis of non-peptidic α-helix and β-turn mimetics". Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627463.
Повний текст джерелаClaudel, Stéphanie. "Les peptides Vinylogues : des nouveaux outils pour la préparation d'analogues contraints de la substance P, de γ-aminoacides α, β-hydroxylés et de dihydroxylactames". Nancy 1, 2004. http://www.theses.fr/2004NAN10039.
Повний текст джерелаThis work concerns conception and synthesis of modified peptides and is divided in two parts. Firstly, it's the insertion of vinylogous amino acids with cis and trans conformation in neuropeptide of eleven amino acids which is substance P in order to understand its interaction with NK-1 receptor. A second study has been oriented on the preparation of g-amino peptides by hydrogenation of previous vinylogous amino acids. This structural modification has given a new SP's analog which has been tested. The second part is the methodology of synthesis using vinylogous peptides and is divided in three chapters. First one presents dihydroxylation's results of these residues with an asymmetric induction using chiral catalyst to obtain dihydroxylated g-amino acids. Second one is an application of these studies with a total synthesis of natural product extracted from nyctinastic plant. And the last one deals with preparation of dihydroxylated lactams leading to the synthesis of new azasugars
Частини книг з теми "Α/β Peptide"
Hartsock, Wendy J., and Robert S. Hodges. "Rational Design of Amphipathic α-Helical and Cyclic β-Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential." In Peptide Drug Discovery and Development, 91–117. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527636730.ch4.
Повний текст джерелаSingh, T. P., B. Padmanabhan, P. Narula, A. K. Saxena, C. Betzel, P. Sharma, and S. Dey. "Design of Specific Peptide Structures and Subtilisin Enzyme Inhibitors Using α, β-Dehydro-Residues." In Advances in Experimental Medicine and Biology, 11–20. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0319-0_3.
Повний текст джерелаBlaskovich, M. A., and G. A. Lajoie. "Stereoselective synthesis of β-substituted-β-hydroxy α-amino acids and β,γ-unsaturated α-amino acids from serine and threonine." In Peptides, 167–69. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_52.
Повний текст джерелаBoitel, Brigitte, Myriam Ermonval, Ulrich Blank, and Oreste Acuto. "T-Cell Antigen and MHC Recognition: Molecular Analysis of Human α/β TCR Specific for a Tetanus Toxin-Derived Peptide." In T Lymphocytes, 1–16. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3054-1_1.
Повний текст джерелаLong, Yi-cheng, Fei-ning Ye, Yun-hua Ye, and Qi-yi Xing. "Studies on the interconversions of the neuroexcitotoxin β-N-oxalo-L-α, β-diaminopropionic acid from Panax species and its isomer α-N-oxalo-L-α, β-diaminopropionic acid." In Peptides, 189–90. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_55.
Повний текст джерелаBlaskovich, M. A., A. W. Wong, and G. A. Lajoie. "Synthesis of optically enriched β,γ-unsaturated α-amino acids." In Peptides 1994, 205–6. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_85.
Повний текст джерелаTung, Roger D., Chong-Qing Sun, Don Deyo, and Daniel H. Rich. "Asymmetric syntheses of β-OH and β-OH, γ-alkyl α-amino acids: Analogs of the unusual cyclosporin amino acid MeBmt." In Peptides, 149–51. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_43.
Повний текст джерелаDiaz-Diaz, M., S. Mzengeza, O. P. Ward, J. F. Honek, and G. Lajoie. "Asymmetric synthesis of β-hydroxy L-α-amino acids using aldolase from Pseudomonas sp." In Peptides, 517–18. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_198.
Повний текст джерелаViso, Alma, and Roberto Fernández de la Pradilla. "Synthetic Approaches to α,β-Diamino Acids." In Amino Acids, Peptides and Proteins in Organic Chemistry, 411–40. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527631766.ch9.
Повний текст джерелаIbuka, T., K. Nakai, H. Habashita, Y. Hotta, A. Otaka, N. Fujii, N. Mimura, Y. Miwa, T. Taga, and Y. Yamamoto. "A new route to stereochemically pure (E)-alkene dipeptide isosteres from β-aziridino-α,β-enoates via organocopper reaction." In Peptides 1994, 674–75. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_309.
Повний текст джерелаТези доповідей конференцій з теми "Α/β Peptide"
Lasota, Anika, Oliwia Fraczak, Adriana Muchowska, Aleksandra Misicka, Michal Nowakowski, Maciej Maciejczyk, Andrzej Ejchart та Aleksandra Olma. "Structure-Activity Relationships of Constrained Dermorphin Analogues Containing an α-Alkyl-β-Substituted Alanines". У The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.073.
Повний текст джерелаBezeaud, A., та M. C. Guillin. "FUNCTIONAL CHARACTERIZATION OF HUMAN β-THROMBIN". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644665.
Повний текст джерелаBacon-Baguley, Theresa, Suzanne Kendra-Franczak та Daniel Walz. "THROMBOSPONDIN SPECIFICALLY INTERACTS WITH AMINO ACID SEQUENCES WITHIN THE A α- AND B β- CHAINS OF FIBRINOGEN". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643822.
Повний текст джерелаDejana, E., F. Breviario, F. Bussolino, L. Mussoni, and A. Mantovani. "PLEIOTROPIC EFFECT OF INTERLEUKIN-1 ON ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643984.
Повний текст джерелаBerndt, M. C., X. Du, L. Beutler, W. J. Booth, and P. A. Castaldi. "LOCALIZATION OF FUNCTIONAL DOMAINS ON HUMAN PLATELET GP Ib-IX COMPLEX BY EPITOPE ANALYSIS WITH MONOCLONAL ANTIBODIES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642923.
Повний текст джерелаBlodgett, Karl, Timothy Zwier та Patrick Walsh. "SINGLE-CONFORMATION IR AND UV SPECTROSCOPY OF A PROTOTYPICAL HETEROGENEOUS α/β-PEPTIDE: IS IT A MIXED-HELIX FORMER?" У 71st International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2016. http://dx.doi.org/10.15278/isms.2016.mi12.
Повний текст джерелаKwon, Sunkuk, Shi Ke, Jessica P. Houston, Wei Wang, Qingping Wu, Chun Li та Eva M. Sevick Muraca. "In vivo pharmacokinetic analysis for fluorescently labeled RGD peptide targeted to the α v β 3 integrin in Kaposi"s sarcoma". У Biomedical Optics 2005, редактор David Kessel. SPIE, 2005. http://dx.doi.org/10.1117/12.589399.
Повний текст джерелаHantgan, R. R. "LOCALIZATION OF THE DOMAINS OF FIBRIN INVOLVED IN BINDING TO PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643773.
Повний текст джерелаValensin, Daniela, Henryk Kozlowski, Isabella Tessari, Simone Dell'Acqua, Luigi Bubacco, Luigi Casella, Elena Gaggelli та Gianni Valensin. "Interactions of metal ions with α synuclein and amyloid β peptides". У INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2014 (ICCMSE 2014). AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4897691.
Повний текст джерелаHan, Zhihao, Shuaishuai Gong, Zhiyu Qian та Yueqing Gu. "Virtual screened peptides with high affinity to integrin α 5 β 1 for precise tumor identification and treatment". У Biophotonics and Immune Responses XV, редактор Wei R. Chen. SPIE, 2020. http://dx.doi.org/10.1117/12.2544502.
Повний текст джерела